akufeldt/covid_qa_ak_203 · Datasets at Hugging Face

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Frontiers in antiviral therapy and immunotherapy https://doi.org/10.1002/cti2.1115 SHA: facbfdfa7189ca9ff83dc30e5d241ab22e962dbf Authors: Heaton, Steven M Date: 2020 DOI: 10.1002/cti2.1115 License: cc-by Abstract: nan Text: Globally, recent decades have witnessed a growing disjunction, a 'Valley of Death' 1,2 no l...	2,669	What growing dysjunction has been witnessed?	{ "answer_start": [ 292 ], "text": [ "a 'Valley of Death' 1,2 no less, between broadening strides in fundamental biomedical research and their incommensurate reach into the clinic. " ] }	4123	[ 0, 2264, 1197, 25599, 267, 38665, 34, 57, 6957, 116, 2, 2, 35985, 4733, 11, 33561, 24811, 5804, 8, 13998, 18189, 50118, 50118, 13082, 640, 39159, 4, 1957, 73, 698, 4, 1866, 176, 73, 3894, 118, 176, 4, 1225, 996, 50118, 50118, 45004,...	[ 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1...	[ [ 0, 0 ], [ 0, 4 ], [ 5, 12 ], [ 13, 16 ], [ 16, 17 ], [ 17, 24 ], [ 25, 28 ], [ 29, 33 ], [ 34, 43 ], [ 43, 44 ], [ 0, 0 ], [ 0, 0 ], [ 0, 5 ], [ 5, 9 ...	292	313
Frontiers in antiviral therapy and immunotherapy https://doi.org/10.1002/cti2.1115 SHA: facbfdfa7189ca9ff83dc30e5d241ab22e962dbf Authors: Heaton, Steven M Date: 2020 DOI: 10.1002/cti2.1115 License: cc-by Abstract: nan Text: Globally, recent decades have witnessed a growing disjunction, a 'Valley of Death' 1,2 no l...	2,669	What is aiming to incorporate pathways to translation at the earliest stages?	{ "answer_start": [ 502 ], "text": [ " recent changes in the structure of government funding, 2 new public and private joint ventures and specialist undergraduate and postgraduate courses" ] }	4124	[ 0, 2264, 16, 9998, 7, 14518, 25019, 7, 19850, 23, 5, 13342, 5612, 116, 2, 2, 35985, 4733, 11, 33561, 24811, 5804, 8, 13998, 18189, 50118, 50118, 13082, 640, 39159, 4, 1957, 73, 698, 4, 1866, 176, 73, 3894, 118, 176, 4, 1225, 996, ...	[ 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1...	[ [ 0, 0 ], [ 0, 4 ], [ 5, 7 ], [ 8, 14 ], [ 15, 17 ], [ 18, 29 ], [ 30, 38 ], [ 39, 41 ], [ 42, 53 ], [ 54, 56 ], [ 57, 60 ], [ 61, 69 ], [ 70, 76 ], [ 76, ...	502	523
Frontiers in antiviral therapy and immunotherapy https://doi.org/10.1002/cti2.1115 SHA: facbfdfa7189ca9ff83dc30e5d241ab22e962dbf Authors: Heaton, Steven M Date: 2020 DOI: 10.1002/cti2.1115 License: cc-by Abstract: nan Text: Globally, recent decades have witnessed a growing disjunction, a 'Valley of Death' 1,2 no l...	2,669	How much have the number of biomedical research publications targeting 'translational' concepts has increased ?	{ "answer_start": [ 842 ], "text": [ "exponentially, up 1800%" ] }	4125	[ 0, 6179, 203, 1437, 33, 1437, 5, 346, 9, 35241, 557, 16043, 5551, 128, 9981, 462, 5033, 108, 14198, 34, 1130, 17487, 2, 2, 35985, 4733, 11, 33561, 24811, 5804, 8, 13998, 18189, 50118, 50118, 13082, 640, 39159, 4, 1957, 73, 698, 4, ...	[ 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1...	[ [ 0, 0 ], [ 0, 3 ], [ 4, 8 ], [ 9, 9 ], [ 10, 14 ], [ 15, 15 ], [ 16, 19 ], [ 20, 26 ], [ 27, 29 ], [ 30, 40 ], [ 41, 49 ], [ 50, 62 ], [ 63, 72 ], [ 73, ...	842	845
Frontiers in antiviral therapy and immunotherapy https://doi.org/10.1002/cti2.1115 SHA: facbfdfa7189ca9ff83dc30e5d241ab22e962dbf Authors: Heaton, Steven M Date: 2020 DOI: 10.1002/cti2.1115 License: cc-by Abstract: nan Text: Globally, recent decades have witnessed a growing disjunction, a 'Valley of Death' 1,2 no l...	2,669	What ways to solve the issues are outlined?	{ "answer_start": [ 2042 ], "text": [ "by creatively leveraging the so-called 'strengths' of viruses. Viral RNA polymerisation and reverse transcription enable resistance to treatment by conferring extraordinary genetic diversity. " ] }	4126	[ 0, 2264, 1319, 7, 1437, 6136, 5, 743, 32, 10634, 116, 2, 2, 35985, 4733, 11, 33561, 24811, 5804, 8, 13998, 18189, 50118, 50118, 13082, 640, 39159, 4, 1957, 73, 698, 4, 1866, 176, 73, 3894, 118, 176, 4, 1225, 996, 50118, 50118, 450...	[ 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1...	[ [ 0, 0 ], [ 0, 4 ], [ 5, 9 ], [ 10, 12 ], [ 13, 13 ], [ 14, 19 ], [ 20, 23 ], [ 24, 30 ], [ 31, 34 ], [ 35, 43 ], [ 43, 44 ], [ 0, 0 ], [ 0, 0 ], [ 0, 5...	2,042	2,065
Frontiers in antiviral therapy and immunotherapy https://doi.org/10.1002/cti2.1115 SHA: facbfdfa7189ca9ff83dc30e5d241ab22e962dbf Authors: Heaton, Steven M Date: 2020 DOI: 10.1002/cti2.1115 License: cc-by Abstract: nan Text: Globally, recent decades have witnessed a growing disjunction, a 'Valley of Death' 1,2 no l...	2,669	How do these exact processes ultimately restrict viral infectivity?	{ "answer_start": [ 2302 ], "text": [ " by strongly limiting virus genome sizes and their incorporation of new information. " ] }	4127	[ 0, 6179, 109, 209, 6089, 5588, 3284, 14058, 7696, 27802, 9866, 116, 2, 2, 35985, 4733, 11, 33561, 24811, 5804, 8, 13998, 18189, 50118, 50118, 13082, 640, 39159, 4, 1957, 73, 698, 4, 1866, 176, 73, 3894, 118, 176, 4, 1225, 996, 50118...	[ 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1...	[ [ 0, 0 ], [ 0, 3 ], [ 4, 6 ], [ 7, 12 ], [ 13, 18 ], [ 19, 28 ], [ 29, 39 ], [ 40, 48 ], [ 49, 54 ], [ 55, 61 ], [ 61, 66 ], [ 66, 67 ], [ 0, 0 ], [ 0, ...	2,302	2,314
Frontiers in antiviral therapy and immunotherapy https://doi.org/10.1002/cti2.1115 SHA: facbfdfa7189ca9ff83dc30e5d241ab22e962dbf Authors: Heaton, Steven M Date: 2020 DOI: 10.1002/cti2.1115 License: cc-by Abstract: nan Text: Globally, recent decades have witnessed a growing disjunction, a 'Valley of Death' 1,2 no l...	2,669	What does the author coin this evolutionary dilemma as?	{ "answer_start": [ 2424 ], "text": [ "'information economy paradox'." ] }	4128	[ 0, 2264, 473, 5, 2730, 12911, 42, 29832, 21949, 25, 116, 2, 2, 35985, 4733, 11, 33561, 24811, 5804, 8, 13998, 18189, 50118, 50118, 13082, 640, 39159, 4, 1957, 73, 698, 4, 1866, 176, 73, 3894, 118, 176, 4, 1225, 996, 50118, 50118, ...	[ 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1...	[ [ 0, 0 ], [ 0, 4 ], [ 5, 9 ], [ 10, 13 ], [ 14, 20 ], [ 21, 25 ], [ 26, 30 ], [ 31, 43 ], [ 44, 51 ], [ 52, 54 ], [ 54, 55 ], [ 0, 0 ], [ 0, 0 ], [ 0, 5...	2,424	2,427
Frontiers in antiviral therapy and immunotherapy https://doi.org/10.1002/cti2.1115 SHA: facbfdfa7189ca9ff83dc30e5d241ab22e962dbf Authors: Heaton, Steven M Date: 2020 DOI: 10.1002/cti2.1115 License: cc-by Abstract: nan Text: Globally, recent decades have witnessed a growing disjunction, a 'Valley of Death' 1,2 no l...	2,669	How do many viruses resolve this ?	{ "answer_start": [ 2492 ], "text": [ "by manipulating multifunctional or multitasking host cell proteins (MMHPs), thereby maximising host subversion and viral infectivity at minimal informational cost." ] }	4129	[ 0, 6179, 109, 171, 21717, 5728, 42, 17487, 2, 2, 35985, 4733, 11, 33561, 24811, 5804, 8, 13998, 18189, 50118, 50118, 13082, 640, 39159, 4, 1957, 73, 698, 4, 1866, 176, 73, 3894, 118, 176, 4, 1225, 996, 50118, 50118, 45004, 35, 11778...	[ 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1...	[ [ 0, 0 ], [ 0, 3 ], [ 4, 6 ], [ 7, 11 ], [ 12, 19 ], [ 20, 27 ], [ 28, 32 ], [ 33, 34 ], [ 0, 0 ], [ 0, 0 ], [ 0, 5 ], [ 5, 9 ], [ 10, 12 ], [ 13, 18 ...	2,492	2,512
Frontiers in antiviral therapy and immunotherapy https://doi.org/10.1002/cti2.1115 SHA: facbfdfa7189ca9ff83dc30e5d241ab22e962dbf Authors: Heaton, Steven M Date: 2020 DOI: 10.1002/cti2.1115 License: cc-by Abstract: nan Text: Globally, recent decades have witnessed a growing disjunction, a 'Valley of Death' 1,2 no l...	2,669	How may this "Achilles Heel" be safely targeted?	{ "answer_start": [ 2725 ], "text": [ " via host-oriented therapies to impose devastating informational and fitness barriers on escape mutant selection." ] }	4130	[ 0, 6179, 189, 42, 22, 250, 611, 22244, 91, 523, 113, 28, 7385, 3656, 116, 2, 2, 35985, 4733, 11, 33561, 24811, 5804, 8, 13998, 18189, 50118, 50118, 13082, 640, 39159, 4, 1957, 73, 698, 4, 1866, 176, 73, 3894, 118, 176, 4, 1225, ...	[ 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1...	[ [ 0, 0 ], [ 0, 3 ], [ 4, 7 ], [ 8, 12 ], [ 13, 14 ], [ 14, 15 ], [ 15, 17 ], [ 17, 22 ], [ 23, 25 ], [ 25, 27 ], [ 27, 28 ], [ 29, 31 ], [ 32, 38 ], [ 39, ...	2,725	2,739
Frontiers in antiviral therapy and immunotherapy https://doi.org/10.1002/cti2.1115 SHA: facbfdfa7189ca9ff83dc30e5d241ab22e962dbf Authors: Heaton, Steven M Date: 2020 DOI: 10.1002/cti2.1115 License: cc-by Abstract: nan Text: Globally, recent decades have witnessed a growing disjunction, a 'Valley of Death' 1,2 no l...	2,669	Why may MMHP-targeting therapies exhibit both robust and broadspectrum antiviral efficacy?	{ "answer_start": [ 2852 ], "text": [ "since MMHPs are often conserved targets within and between virus families," ] }	4131	[ 0, 7608, 1437, 189, 24537, 7331, 12, 23976, 154, 17094, 8483, 258, 6295, 8, 4007, 25594, 10904, 33561, 24811, 22081, 116, 2, 2, 35985, 4733, 11, 33561, 24811, 5804, 8, 13998, 18189, 50118, 50118, 13082, 640, 39159, 4, 1957, 73, 698, 4...	[ 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1...	[ [ 0, 0 ], [ 0, 3 ], [ 4, 4 ], [ 5, 8 ], [ 9, 11 ], [ 11, 13 ], [ 13, 14 ], [ 14, 20 ], [ 20, 23 ], [ 24, 33 ], [ 34, 41 ], [ 42, 46 ], [ 47, 53 ], [ 54, ...	2,852	2,863
Frontiers in antiviral therapy and immunotherapy https://doi.org/10.1002/cti2.1115 SHA: facbfdfa7189ca9ff83dc30e5d241ab22e962dbf Authors: Heaton, Steven M Date: 2020 DOI: 10.1002/cti2.1115 License: cc-by Abstract: nan Text: Globally, recent decades have witnessed a growing disjunction, a 'Valley of Death' 1,2 no l...	2,669	What will achieving this through drug repurposing do?	{ "answer_start": [ 3058 ], "text": [ " break the vicious cycle of escalating therapeutic development costs and trivial escape mutant selection, both quickly and in multiple places. " ] }	4132	[ 0, 2264, 40, 1437, 9499, 42, 149, 1262, 2851, 710, 29105, 109, 116, 2, 2, 35985, 4733, 11, 33561, 24811, 5804, 8, 13998, 18189, 50118, 50118, 13082, 640, 39159, 4, 1957, 73, 698, 4, 1866, 176, 73, 3894, 118, 176, 4, 1225, 996, 501...	[ 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1...	[ [ 0, 0 ], [ 0, 4 ], [ 5, 9 ], [ 10, 10 ], [ 11, 20 ], [ 21, 25 ], [ 26, 33 ], [ 34, 38 ], [ 39, 42 ], [ 42, 44 ], [ 44, 50 ], [ 51, 53 ], [ 53, 54 ], [ 0, ...	3,058	3,078
Frontiers in antiviral therapy and immunotherapy https://doi.org/10.1002/cti2.1115 SHA: facbfdfa7189ca9ff83dc30e5d241ab22e962dbf Authors: Heaton, Steven M Date: 2020 DOI: 10.1002/cti2.1115 License: cc-by Abstract: nan Text: Globally, recent decades have witnessed a growing disjunction, a 'Valley of Death' 1,2 no l...	2,669	What are also discussed by the author?	{ "answer_start": [ 3215 ], "text": [ " alternative posttranslational and RNA-based antiviral approaches, designer vaccines, immunotherapy and the emerging field of neo-virology." ] }	4133	[ 0, 2264, 32, 67, 3373, 30, 5, 2730, 116, 2, 2, 35985, 4733, 11, 33561, 24811, 5804, 8, 13998, 18189, 50118, 50118, 13082, 640, 39159, 4, 1957, 73, 698, 4, 1866, 176, 73, 3894, 118, 176, 4, 1225, 996, 50118, 50118, 45004, 35, 11778...	[ 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1...	[ [ 0, 0 ], [ 0, 4 ], [ 5, 8 ], [ 9, 13 ], [ 14, 23 ], [ 24, 26 ], [ 27, 30 ], [ 31, 37 ], [ 37, 38 ], [ 0, 0 ], [ 0, 0 ], [ 0, 5 ], [ 5, 9 ], [ 10, 12 ...	3,215	3,230

Frontiers in antiviral therapy and immunotherapy https://doi.org/10.1002/cti2.1115 SHA: facbfdfa7189ca9ff83dc30e5d241ab22e962dbf Authors: Heaton, Steven M Date: 2020 DOI: 10.1002/cti2.1115 License: cc-by Abstract: nan Text: Globally, recent decades have witnessed a growing disjunction, a 'Valley of Death' 1,2 no l...

2,669

What growing dysjunction has been witnessed?

{ "answer_start": [ 292 ], "text": [ "a 'Valley of Death' 1,2 no less, between broadening strides in fundamental biomedical research and their incommensurate reach into the clinic. " ] }

4123

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Frontiers in antiviral therapy and immunotherapy https://doi.org/10.1002/cti2.1115 SHA: facbfdfa7189ca9ff83dc30e5d241ab22e962dbf Authors: Heaton, Steven M Date: 2020 DOI: 10.1002/cti2.1115 License: cc-by Abstract: nan Text: Globally, recent decades have witnessed a growing disjunction, a 'Valley of Death' 1,2 no l...

2,669

What is aiming to incorporate pathways to translation at the earliest stages?

{ "answer_start": [ 502 ], "text": [ " recent changes in the structure of government funding, 2 new public and private joint ventures and specialist undergraduate and postgraduate courses" ] }

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Frontiers in antiviral therapy and immunotherapy https://doi.org/10.1002/cti2.1115 SHA: facbfdfa7189ca9ff83dc30e5d241ab22e962dbf Authors: Heaton, Steven M Date: 2020 DOI: 10.1002/cti2.1115 License: cc-by Abstract: nan Text: Globally, recent decades have witnessed a growing disjunction, a 'Valley of Death' 1,2 no l...

2,669

How much have the number of biomedical research publications targeting 'translational' concepts has increased ?

{ "answer_start": [ 842 ], "text": [ "exponentially, up 1800%" ] }

4125

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Frontiers in antiviral therapy and immunotherapy https://doi.org/10.1002/cti2.1115 SHA: facbfdfa7189ca9ff83dc30e5d241ab22e962dbf Authors: Heaton, Steven M Date: 2020 DOI: 10.1002/cti2.1115 License: cc-by Abstract: nan Text: Globally, recent decades have witnessed a growing disjunction, a 'Valley of Death' 1,2 no l...

2,669

What ways to solve the issues are outlined?

{ "answer_start": [ 2042 ], "text": [ "by creatively leveraging the so-called 'strengths' of viruses. Viral RNA polymerisation and reverse transcription enable resistance to treatment by conferring extraordinary genetic diversity. " ] }

4126

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Frontiers in antiviral therapy and immunotherapy https://doi.org/10.1002/cti2.1115 SHA: facbfdfa7189ca9ff83dc30e5d241ab22e962dbf Authors: Heaton, Steven M Date: 2020 DOI: 10.1002/cti2.1115 License: cc-by Abstract: nan Text: Globally, recent decades have witnessed a growing disjunction, a 'Valley of Death' 1,2 no l...

2,669

How do these exact processes ultimately restrict viral infectivity?

{ "answer_start": [ 2302 ], "text": [ " by strongly limiting virus genome sizes and their incorporation of new information. " ] }

4127

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Frontiers in antiviral therapy and immunotherapy https://doi.org/10.1002/cti2.1115 SHA: facbfdfa7189ca9ff83dc30e5d241ab22e962dbf Authors: Heaton, Steven M Date: 2020 DOI: 10.1002/cti2.1115 License: cc-by Abstract: nan Text: Globally, recent decades have witnessed a growing disjunction, a 'Valley of Death' 1,2 no l...

2,669

What does the author coin this evolutionary dilemma as?

{ "answer_start": [ 2424 ], "text": [ "'information economy paradox'." ] }

4128

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Frontiers in antiviral therapy and immunotherapy https://doi.org/10.1002/cti2.1115 SHA: facbfdfa7189ca9ff83dc30e5d241ab22e962dbf Authors: Heaton, Steven M Date: 2020 DOI: 10.1002/cti2.1115 License: cc-by Abstract: nan Text: Globally, recent decades have witnessed a growing disjunction, a 'Valley of Death' 1,2 no l...

2,669

How do many viruses resolve this ?

{ "answer_start": [ 2492 ], "text": [ "by manipulating multifunctional or multitasking host cell proteins (MMHPs), thereby maximising host subversion and viral infectivity at minimal informational cost." ] }

4129

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Frontiers in antiviral therapy and immunotherapy https://doi.org/10.1002/cti2.1115 SHA: facbfdfa7189ca9ff83dc30e5d241ab22e962dbf Authors: Heaton, Steven M Date: 2020 DOI: 10.1002/cti2.1115 License: cc-by Abstract: nan Text: Globally, recent decades have witnessed a growing disjunction, a 'Valley of Death' 1,2 no l...

2,669

How may this "Achilles Heel" be safely targeted?

{ "answer_start": [ 2725 ], "text": [ " via host-oriented therapies to impose devastating informational and fitness barriers on escape mutant selection." ] }

4130

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Frontiers in antiviral therapy and immunotherapy https://doi.org/10.1002/cti2.1115 SHA: facbfdfa7189ca9ff83dc30e5d241ab22e962dbf Authors: Heaton, Steven M Date: 2020 DOI: 10.1002/cti2.1115 License: cc-by Abstract: nan Text: Globally, recent decades have witnessed a growing disjunction, a 'Valley of Death' 1,2 no l...

2,669

Why may MMHP-targeting therapies exhibit both robust and broadspectrum antiviral efficacy?

{ "answer_start": [ 2852 ], "text": [ "since MMHPs are often conserved targets within and between virus families," ] }

4131

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Frontiers in antiviral therapy and immunotherapy https://doi.org/10.1002/cti2.1115 SHA: facbfdfa7189ca9ff83dc30e5d241ab22e962dbf Authors: Heaton, Steven M Date: 2020 DOI: 10.1002/cti2.1115 License: cc-by Abstract: nan Text: Globally, recent decades have witnessed a growing disjunction, a 'Valley of Death' 1,2 no l...

2,669

What will achieving this through drug repurposing do?

{ "answer_start": [ 3058 ], "text": [ " break the vicious cycle of escalating therapeutic development costs and trivial escape mutant selection, both quickly and in multiple places. " ] }

4132

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Frontiers in antiviral therapy and immunotherapy https://doi.org/10.1002/cti2.1115 SHA: facbfdfa7189ca9ff83dc30e5d241ab22e962dbf Authors: Heaton, Steven M Date: 2020 DOI: 10.1002/cti2.1115 License: cc-by Abstract: nan Text: Globally, recent decades have witnessed a growing disjunction, a 'Valley of Death' 1,2 no l...

2,669

What are also discussed by the author?

{ "answer_start": [ 3215 ], "text": [ " alternative posttranslational and RNA-based antiviral approaches, designer vaccines, immunotherapy and the emerging field of neo-virology." ] }

4133

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Datasets:

akufeldt
/

covid_qa_ak_203

Dataset Card for "covid_qa_ak_203"