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. O
The O
present O
method O
also O
identified O
the O
structural O
members O
that O
did O
not O
contribute O
to O
strength S-PRO
and O
rigidity O
, O
which O
in O
turn O
realized O
the O
appropriate O
weight S-PARA
savings O
and O
increased O
the O
specific B-PRO
strength E-PRO
and O
specific B-PRO
stiffness E-PRO
. O
Microstructures S-MATE
with O
spatially-varying O
properties S-CONPRI
such O
as S-MATE
trabecular O
bone S-BIOP
are O
widely O
seen O
in O
nature O
. O
These O
functionally B-MATE
graded I-MATE
materials E-MATE
possess O
smoothly O
changing O
microstructural S-CONPRI
topologies O
that O
enable O
excellent O
micro O
and O
macroscale S-CONPRI
performance O
. O
The O
fabrication S-MANP
of O
such O
microstructural B-CONPRI
materials E-CONPRI
is O
now O
enabled O
by O
additive B-MANP
manufacturing E-MANP
( O
AM S-MANP
) O
. O
A O
challenging O
aspect O
in O
the O
computational O
design S-FEAT
of O