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10036953_participants
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract participant-related spans from the abstract.\n\nInclude spans that describe the patient/population, such as:\n- disease/condition population terms\n- demographic descriptors (for example age/sex g...
[ { "role": "assistant", "content": "**Answer:** 99\nH. pylori infection\n" } ]
99 H. pylori infection
10036953_interventions
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract intervention/comparator-related spans from the abstract.\n\nInclude spans that describe treatment arms or comparators, such as:\n- drug/device/procedure/intervention names\n- comparator/control/pl...
[ { "role": "assistant", "content": "**Answer:** H2 blockaders\nranitidine\nlansoprazole\nantisecretory drugs\nlansoprazole\nranitidine\nclarithromycin ( CAM )\nmetrinidazole ( MTZ )\nLPZ\nCAM\nMTZ\nranitidine\nRNT\nCAM\nMTZ\nLCM\nRCM\n" } ]
H2 blockaders ranitidine lansoprazole antisecretory drugs lansoprazole ranitidine clarithromycin ( CAM ) metrinidazole ( MTZ ) LPZ CAM MTZ ranitidine RNT CAM MTZ LCM RCM
10036953_outcomes
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract outcome-related spans from the abstract.\n\nInclude spans that describe measured endpoints/results concepts, such as:\n- named outcomes/endpoints\n- symptom scores or clinical measures\n- adverse ...
[ { "role": "assistant", "content": "**Answer:** Helicobacter pylori infections ]\nComparison\nefficacy and safety\ncure rate of H.\npylori infection\n" } ]
Helicobacter pylori infections ] Comparison efficacy and safety cure rate of H. pylori infection
10037531_participants
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract participant-related spans from the abstract.\n\nInclude spans that describe the patient/population, such as:\n- disease/condition population terms\n- demographic descriptors (for example age/sex g...
[ { "role": "assistant", "content": "**Answer:** acute otitis media .\n" } ]
acute otitis media .
10037531_interventions
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract intervention/comparator-related spans from the abstract.\n\nInclude spans that describe treatment arms or comparators, such as:\n- drug/device/procedure/intervention names\n- comparator/control/pl...
[ { "role": "assistant", "content": "**Answer:** Xylitol\n" } ]
Xylitol
10037531_outcomes
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract outcome-related spans from the abstract.\n\nInclude spans that describe measured endpoints/results concepts, such as:\n- named outcomes/endpoints\n- symptom scores or clinical measures\n- adverse ...
[ { "role": "assistant", "content": "**Answer:** None\n" } ]
None
10052279_participants
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract participant-related spans from the abstract.\n\nInclude spans that describe the patient/population, such as:\n- disease/condition population terms\n- demographic descriptors (for example age/sex g...
[ { "role": "assistant", "content": "**Answer:** Forty-five\n" } ]
Forty-five
10052279_interventions
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract intervention/comparator-related spans from the abstract.\n\nInclude spans that describe treatment arms or comparators, such as:\n- drug/device/procedure/intervention names\n- comparator/control/pl...
[ { "role": "assistant", "content": "**Answer:** Pre-operative short-term pulmonary rehabilitation for\ncoronary artery bypass graft surgery\npre-operative short-term pulmonary rehabilitation\ncoronary artery\nshort-term pulmonary rehabilitation\nno such programme\n" } ]
Pre-operative short-term pulmonary rehabilitation for coronary artery bypass graft surgery pre-operative short-term pulmonary rehabilitation coronary artery short-term pulmonary rehabilitation no such programme
10052279_outcomes
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract outcome-related spans from the abstract.\n\nInclude spans that describe measured endpoints/results concepts, such as:\n- named outcomes/endpoints\n- symptom scores or clinical measures\n- adverse ...
[ { "role": "assistant", "content": "**Answer:** Pre-operative and post-operative peak expiratory flow rate\ninspiratory capacity\npost-operative ventilation time\npost-operative pulmonary complication\nhospital stay\nPeak expiratory flow rate\ninspiratory capacity\nrise in post-operative peak expiratory flow...
Pre-operative and post-operative peak expiratory flow rate inspiratory capacity post-operative ventilation time post-operative pulmonary complication hospital stay Peak expiratory flow rate inspiratory capacity rise in post-operative peak expiratory flow rate inspiratory capacity after surgery post-operative peak expir...
10071998_participants
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract participant-related spans from the abstract.\n\nInclude spans that describe the patient/population, such as:\n- disease/condition population terms\n- demographic descriptors (for example age/sex g...
[ { "role": "assistant", "content": "**Answer:** in vitro fertilization :\nwomen\nultrasonically guided oocyte retrieval\nSeventy-eight\nwomen\n" } ]
in vitro fertilization : women ultrasonically guided oocyte retrieval Seventy-eight women
10071998_interventions
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract intervention/comparator-related spans from the abstract.\n\nInclude spans that describe treatment arms or comparators, such as:\n- drug/device/procedure/intervention names\n- comparator/control/pl...
[ { "role": "assistant", "content": "**Answer:** fentanyl\nlidocaine .\nSpinal anesthesia\n45 mg of hyperbaric 1.5 % lidocaine with or without 10 microg of fentanyl .\n" } ]
fentanyl lidocaine . Spinal anesthesia 45 mg of hyperbaric 1.5 % lidocaine with or without 10 microg of fentanyl .
10071998_outcomes
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract outcome-related spans from the abstract.\n\nInclude spans that describe measured endpoints/results concepts, such as:\n- named outcomes/endpoints\n- symptom scores or clinical measures\n- adverse ...
[ { "role": "assistant", "content": "**Answer:** Visual analog scale ( VAS ) pain scores\namount of narcotic required\nVAS scores\namount of analgesics and narcotics required after discharge\nTimed variables , such as\ntime to urination\n,\nambulation\n, and discharge\n" } ]
Visual analog scale ( VAS ) pain scores amount of narcotic required VAS scores amount of analgesics and narcotics required after discharge Timed variables , such as time to urination , ambulation , and discharge
10075386_participants
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract participant-related spans from the abstract.\n\nInclude spans that describe the patient/population, such as:\n- disease/condition population terms\n- demographic descriptors (for example age/sex g...
[ { "role": "assistant", "content": "**Answer:** hypertensive patients :\n36 never-treated mild to moderate hypertensive patients .\n" } ]
hypertensive patients : 36 never-treated mild to moderate hypertensive patients .
10075386_interventions
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract intervention/comparator-related spans from the abstract.\n\nInclude spans that describe treatment arms or comparators, such as:\n- drug/device/procedure/intervention names\n- comparator/control/pl...
[ { "role": "assistant", "content": "**Answer:** insufficient sleep\n24-h blood pressure monitoring\nsleep deprivation\nfull night 's sleep\nsleep-deprivation\nsleep deprivation\nsleep-insufficient\n" } ]
insufficient sleep 24-h blood pressure monitoring sleep deprivation full night 's sleep sleep-deprivation sleep deprivation sleep-insufficient
10075386_outcomes
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract outcome-related spans from the abstract.\n\nInclude spans that describe measured endpoints/results concepts, such as:\n- named outcomes/endpoints\n- symptom scores or clinical measures\n- adverse ...
[ { "role": "assistant", "content": "**Answer:** blood pressure\nblood pressure\nexcretion of norepinephrine\nblood pressure\nUrinary excretion of norepinephrine\nBlood pressure\nheart rate\nsympathetic nervous activity\nblood pressure\nheart rate\nrisk for both target organ damage and acute cardiovascular di...
blood pressure blood pressure excretion of norepinephrine blood pressure Urinary excretion of norepinephrine Blood pressure heart rate sympathetic nervous activity blood pressure heart rate risk for both target organ damage and acute cardiovascular diseases
10077140_participants
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract participant-related spans from the abstract.\n\nInclude spans that describe the patient/population, such as:\n- disease/condition population terms\n- demographic descriptors (for example age/sex g...
[ { "role": "assistant", "content": "**Answer:** None\n" } ]
None
10077140_interventions
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract intervention/comparator-related spans from the abstract.\n\nInclude spans that describe treatment arms or comparators, such as:\n- drug/device/procedure/intervention names\n- comparator/control/pl...
[ { "role": "assistant", "content": "**Answer:** hydrofluoroalkane-134a ( HFA ) albuterol .\nHydrofluoroalkane-134a ( HFA )\nswitched from CFC albuterol to HFA albuterol\neither continue receiving\nCFC albuterol\nto be switched to receive\nHFA albuterol\nin a yearlong safety and efficacy trial\nHFA albuterol\...
hydrofluoroalkane-134a ( HFA ) albuterol . Hydrofluoroalkane-134a ( HFA ) switched from CFC albuterol to HFA albuterol either continue receiving CFC albuterol to be switched to receive HFA albuterol in a yearlong safety and efficacy trial HFA albuterol HFA albuterol
10077140_outcomes
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract outcome-related spans from the abstract.\n\nInclude spans that describe measured endpoints/results concepts, such as:\n- named outcomes/endpoints\n- symptom scores or clinical measures\n- adverse ...
[ { "role": "assistant", "content": "**Answer:** Safety and efficacy\nBronchodilator efficacy\nserial spirometry\nSafety\nchanges in\npulse rate\n,\nblood pressure\n, and\nelectrocardiogram ( ECG )\nintervals\nmonitoring adverse events\nlaboratory testing and physical examinations\n.\nbronchodilator efficacy\...
Safety and efficacy Bronchodilator efficacy serial spirometry Safety changes in pulse rate , blood pressure , and electrocardiogram ( ECG ) intervals monitoring adverse events laboratory testing and physical examinations . bronchodilator efficacy pulse rate , blood pressure , and ECG intervals . Adverse event profiles ...
10078672_participants
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract participant-related spans from the abstract.\n\nInclude spans that describe the patient/population, such as:\n- disease/condition population terms\n- demographic descriptors (for example age/sex g...
[ { "role": "assistant", "content": "**Answer:** healthy\nnon-drug-abusing\nTen\n" } ]
healthy non-drug-abusing Ten
10078672_interventions
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract intervention/comparator-related spans from the abstract.\n\nInclude spans that describe treatment arms or comparators, such as:\n- drug/device/procedure/intervention names\n- comparator/control/pl...
[ { "role": "assistant", "content": "**Answer:** remifentanil\nalfentanil\nremifentanil\nremifentanil\nplacebo-controlled\nsaline\nremifentanil\nalfentanil\nSTANPUMP\ncomputer modeling software package\nremifentanil\nRemifentanil\nremifentanil\n" } ]
remifentanil alfentanil remifentanil remifentanil placebo-controlled saline remifentanil alfentanil STANPUMP computer modeling software package remifentanil Remifentanil remifentanil
10078672_outcomes
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract outcome-related spans from the abstract.\n\nInclude spans that describe measured endpoints/results concepts, such as:\n- named outcomes/endpoints\n- symptom scores or clinical measures\n- adverse ...
[ { "role": "assistant", "content": "**Answer:** Behavioral and physiological effects\nsubjective and psychomotor effects\nprototypic micro-like opioid subjective effects , impaired psychomotor performance , and produced analgesia\nanalgesia\npharmacodynamic effects\npsychomotor effects\n" } ]
Behavioral and physiological effects subjective and psychomotor effects prototypic micro-like opioid subjective effects , impaired psychomotor performance , and produced analgesia analgesia pharmacodynamic effects psychomotor effects
10078673_participants
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract participant-related spans from the abstract.\n\nInclude spans that describe the patient/population, such as:\n- disease/condition population terms\n- demographic descriptors (for example age/sex g...
[ { "role": "assistant", "content": "**Answer:** postoperative patient-controlled epidural analgesia .\nThirty patients undergoing lower abdominal surgery were randomized\n" } ]
postoperative patient-controlled epidural analgesia . Thirty patients undergoing lower abdominal surgery were randomized
10078673_interventions
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract intervention/comparator-related spans from the abstract.\n\nInclude spans that describe treatment arms or comparators, such as:\n- drug/device/procedure/intervention names\n- comparator/control/pl...
[ { "role": "assistant", "content": "**Answer:** ropivacaine/fentanyl\nRopivacaine\nfentanyl\nropivacaine-fentanyl\n0.2 % ropivacaine-4 microg fentanyl 0.1 % ropivacaine-2 microg fentanyl\n0.05 % ropivacaine-1 microg fentanyl\nropivacaine-4\nropivacaine-4\nropivacaine-2\nropivacaine\nfentanyl\nropivacaine\nfe...
ropivacaine/fentanyl Ropivacaine fentanyl ropivacaine-fentanyl 0.2 % ropivacaine-4 microg fentanyl 0.1 % ropivacaine-2 microg fentanyl 0.05 % ropivacaine-1 microg fentanyl ropivacaine-4 ropivacaine-4 ropivacaine-2 ropivacaine fentanyl ropivacaine fentanyl
10078673_outcomes
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract outcome-related spans from the abstract.\n\nInclude spans that describe measured endpoints/results concepts, such as:\n- named outcomes/endpoints\n- symptom scores or clinical measures\n- adverse ...
[ { "role": "assistant", "content": "**Answer:** side effects .\nPain scores ( rest , cough , and ambulation ) , side effects ( nausea , pruritus , sedation , motor block , hypotension , and orthostasis ) , and patient-controlled epidural analgesia consumption\nMotor block\nseverity .\nmotor block\ndeterminan...
side effects . Pain scores ( rest , cough , and ambulation ) , side effects ( nausea , pruritus , sedation , motor block , hypotension , and orthostasis ) , and patient-controlled epidural analgesia consumption Motor block severity . motor block determinant of motor block
10080319_participants
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract participant-related spans from the abstract.\n\nInclude spans that describe the patient/population, such as:\n- disease/condition population terms\n- demographic descriptors (for example age/sex g...
[ { "role": "assistant", "content": "**Answer:** implant-retained mandibular overdentures .\nimplant-retained overdentures\n" } ]
implant-retained mandibular overdentures . implant-retained overdentures
10080319_interventions
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract intervention/comparator-related spans from the abstract.\n\nInclude spans that describe treatment arms or comparators, such as:\n- drug/device/procedure/intervention names\n- comparator/control/pl...
[ { "role": "assistant", "content": "**Answer:** implant-retained overdentures\nmasticatory performance , and the subjective chewing experience\nimplant-supported mandibular overdenture\ntransmandibular implant ( TMI )\n" } ]
implant-retained overdentures masticatory performance , and the subjective chewing experience implant-supported mandibular overdenture transmandibular implant ( TMI )
10080319_outcomes
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract outcome-related spans from the abstract.\n\nInclude spans that describe measured endpoints/results concepts, such as:\n- named outcomes/endpoints\n- symptom scores or clinical measures\n- adverse ...
[ { "role": "assistant", "content": "**Answer:** masticatory performance , and the subjective chewing experience .\nMasticatory performance as well as chewing experience\nmasticatory performance and the variables of chewing experience .\nmasticatory performance and\nfunctional complaints mandibular denture\n....
masticatory performance , and the subjective chewing experience . Masticatory performance as well as chewing experience masticatory performance and the variables of chewing experience . masticatory performance and functional complaints mandibular denture .
10084579_participants
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract participant-related spans from the abstract.\n\nInclude spans that describe the patient/population, such as:\n- disease/condition population terms\n- demographic descriptors (for example age/sex g...
[ { "role": "assistant", "content": "**Answer:** neonatal\ncongenital adrenal hyperplasia\nneonatal\nneonates\nAnother 50 samples\nnewborn\n" } ]
neonatal congenital adrenal hyperplasia neonatal neonates Another 50 samples newborn
10084579_interventions
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract intervention/comparator-related spans from the abstract.\n\nInclude spans that describe treatment arms or comparators, such as:\n- drug/device/procedure/intervention names\n- comparator/control/pl...
[ { "role": "assistant", "content": "**Answer:** Genotyping of CYP21\ngenotyping 9 CYP21\nBlood-impregnated filter papers\n17-hydroxyprogesterone\nCYP21 PCR\nCYP21\nCYP21\n" } ]
Genotyping of CYP21 genotyping 9 CYP21 Blood-impregnated filter papers 17-hydroxyprogesterone CYP21 PCR CYP21 CYP21
10084579_outcomes
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract outcome-related spans from the abstract.\n\nInclude spans that describe measured endpoints/results concepts, such as:\n- named outcomes/endpoints\n- symptom scores or clinical measures\n- adverse ...
[ { "role": "assistant", "content": "**Answer:** feasibility\ndiagnostic utility\nheterozygote rate\n17-OHP levels\n17-OHP\nGenetic linkage disequilibrium\nCYP21\nspecificity\nsensitivity\nCYP21 heterozygote frequency for classic mutations\n" } ]
feasibility diagnostic utility heterozygote rate 17-OHP levels 17-OHP Genetic linkage disequilibrium CYP21 specificity sensitivity CYP21 heterozygote frequency for classic mutations
10089089_participants
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract participant-related spans from the abstract.\n\nInclude spans that describe the patient/population, such as:\n- disease/condition population terms\n- demographic descriptors (for example age/sex g...
[ { "role": "assistant", "content": "**Answer:** fever in neutropenic patients .\n" } ]
fever in neutropenic patients .
10089089_interventions
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract intervention/comparator-related spans from the abstract.\n\nInclude spans that describe treatment arms or comparators, such as:\n- drug/device/procedure/intervention names\n- comparator/control/pl...
[ { "role": "assistant", "content": "**Answer:** Piperacillin/tazobactam\ntobramycin\nceftazidime plus tobramycin\npiperacillin and tazobactam\nceftazidime\ntobramycin\npiperacillin\ntazobactam\ntobramycin\nVancomycin\nceftazidime\npiperacillin/tazobactam\nantibacterial therapy\npiperacillin/tazobactam\ncefta...
Piperacillin/tazobactam tobramycin ceftazidime plus tobramycin piperacillin and tazobactam ceftazidime tobramycin piperacillin tazobactam tobramycin Vancomycin ceftazidime piperacillin/tazobactam antibacterial therapy piperacillin/tazobactam ceftazidime piperacillin/ tazobactam ceftazidime glycopeptide piperacillin/taz...
10089089_outcomes
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract outcome-related spans from the abstract.\n\nInclude spans that describe measured endpoints/results concepts, such as:\n- named outcomes/endpoints\n- symptom scores or clinical measures\n- adverse ...
[ { "role": "assistant", "content": "**Answer:** fever\nfever\nsuccessful\ninfectious death or delay in treatment of underlying disease due to infection\nglycopeptide addition\nefficacy\nempiric glycopeptide antibiotic administration\n" } ]
fever fever successful infectious death or delay in treatment of underlying disease due to infection glycopeptide addition efficacy empiric glycopeptide antibiotic administration
10091821_participants
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract participant-related spans from the abstract.\n\nInclude spans that describe the patient/population, such as:\n- disease/condition population terms\n- demographic descriptors (for example age/sex g...
[ { "role": "assistant", "content": "**Answer:** left ventricular dysfunction\n6,781\n" } ]
left ventricular dysfunction 6,781
10091821_interventions
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract intervention/comparator-related spans from the abstract.\n\nInclude spans that describe treatment arms or comparators, such as:\n- drug/device/procedure/intervention names\n- comparator/control/pl...
[ { "role": "assistant", "content": "**Answer:** sphygmomanometrically determined pulse pressure and mean arterial pressure\ncalcium channel blocking agent\n,\ndigoxin\ndiuretic\ncalcium channel blocker\ndigoxin\nnoninvasive blood pressure measurement\n" } ]
sphygmomanometrically determined pulse pressure and mean arterial pressure calcium channel blocking agent , digoxin diuretic calcium channel blocker digoxin noninvasive blood pressure measurement
10091821_outcomes
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract outcome-related spans from the abstract.\n\nInclude spans that describe measured endpoints/results concepts, such as:\n- named outcomes/endpoints\n- symptom scores or clinical measures\n- adverse ...
[ { "role": "assistant", "content": "**Answer:** pulse pressure\narterial pressure\nmortality\nPulse and mean arterial pressure\nHigher pulse pressure\nHigher mean arterial pressure\ndeaths\npulse pressure\ntotal and cardiovascular mortality\nMean arterial pressure\ntotal and cardiovascular mortality\nsurviva...
pulse pressure arterial pressure mortality Pulse and mean arterial pressure Higher pulse pressure Higher mean arterial pressure deaths pulse pressure total and cardiovascular mortality Mean arterial pressure total and cardiovascular mortality survival Increased conduit vessel stiffness mortality
10093945_participants
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract participant-related spans from the abstract.\n\nInclude spans that describe the patient/population, such as:\n- disease/condition population terms\n- demographic descriptors (for example age/sex g...
[ { "role": "assistant", "content": "**Answer:** typhoid fever\nchildren\nmultidrug-resistant typhoid fever\nchildren\ntyphoid fever\n82\n70\nuncomplicated typhoid fever\nchildren\n" } ]
typhoid fever children multidrug-resistant typhoid fever children typhoid fever 82 70 uncomplicated typhoid fever children
10093945_interventions
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract intervention/comparator-related spans from the abstract.\n\nInclude spans that describe treatment arms or comparators, such as:\n- drug/device/procedure/intervention names\n- comparator/control/pl...
[ { "role": "assistant", "content": "**Answer:** ofloxacin\ncefixime\nfluoroquinolone antibiotics\nCefixime\ncephalosporin\nofloxacin\nofloxacin\ncefixime\ncefixime\nofloxacin\nofloxacin\ncefixime-treated\ncefixime\nofloxacin\ncefixime\nofloxacin\n" } ]
ofloxacin cefixime fluoroquinolone antibiotics Cefixime cephalosporin ofloxacin ofloxacin cefixime cefixime ofloxacin ofloxacin cefixime-treated cefixime ofloxacin cefixime ofloxacin
10093945_outcomes
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract outcome-related spans from the abstract.\n\nInclude spans that describe measured endpoints/results concepts, such as:\n- named outcomes/endpoints\n- symptom scores or clinical measures\n- adverse ...
[ { "role": "assistant", "content": "**Answer:** fever clearance times\ntreatment failures\nacute treatment failure\n" } ]
fever clearance times treatment failures acute treatment failure
10094243_participants
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract participant-related spans from the abstract.\n\nInclude spans that describe the patient/population, such as:\n- disease/condition population terms\n- demographic descriptors (for example age/sex g...
[ { "role": "assistant", "content": "**Answer:** panic disorder\nsocial phobics\nTwenty-nine patients\nten patients\n" } ]
panic disorder social phobics Twenty-nine patients ten patients
10094243_interventions
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract intervention/comparator-related spans from the abstract.\n\nInclude spans that describe treatment arms or comparators, such as:\n- drug/device/procedure/intervention names\n- comparator/control/pl...
[ { "role": "assistant", "content": "**Answer:** epinephrine\nepinephrine\nplacebo .\nepinephrine\nepinephrine-induced\n" } ]
epinephrine epinephrine placebo . epinephrine epinephrine-induced
10094243_outcomes
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract outcome-related spans from the abstract.\n\nInclude spans that describe measured endpoints/results concepts, such as:\n- named outcomes/endpoints\n- symptom scores or clinical measures\n- adverse ...
[ { "role": "assistant", "content": "**Answer:** changes in transcutaneous PCO2 ( tcPCO2 )\nsubjective anxiety\nheart rate\nblood pressure\nfall in tcPCO2\nthe cardiovascular response\ntcPCO2\nacute hyperventilation\nfall in tcPCO2\noccurrence of anxiety-related somatic symptoms\n" } ]
changes in transcutaneous PCO2 ( tcPCO2 ) subjective anxiety heart rate blood pressure fall in tcPCO2 the cardiovascular response tcPCO2 acute hyperventilation fall in tcPCO2 occurrence of anxiety-related somatic symptoms
10097996_participants
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract participant-related spans from the abstract.\n\nInclude spans that describe the patient/population, such as:\n- disease/condition population terms\n- demographic descriptors (for example age/sex g...
[ { "role": "assistant", "content": "**Answer:** pervasive developmental disorders\npervasive developmental disorders ( PDDs ) .\n70\nyoung children\nolder children\nchildren\n12\nchildren\nPDDs\n10\nchildren\nPDDs\n20\nchildren\npsychiatric disorders\nchildren\nAttention-deficit Hyperactivity Disorder\n32\n"...
pervasive developmental disorders pervasive developmental disorders ( PDDs ) . 70 young children older children children 12 children PDDs 10 children PDDs 20 children psychiatric disorders children Attention-deficit Hyperactivity Disorder 32
10097996_interventions
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract intervention/comparator-related spans from the abstract.\n\nInclude spans that describe treatment arms or comparators, such as:\n- drug/device/procedure/intervention names\n- comparator/control/pl...
[ { "role": "assistant", "content": "**Answer:** TOM test\nTOM test\nTOM test\nTOM test\nTOM test\nTOM test\nTOM test\nTOM test\nTOM test\nTOM test\nTOM test\n" } ]
TOM test TOM test TOM test TOM test TOM test TOM test TOM test TOM test TOM test TOM test TOM test
10097996_outcomes
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract outcome-related spans from the abstract.\n\nInclude spans that describe measured endpoints/results concepts, such as:\n- named outcomes/endpoints\n- symptom scores or clinical measures\n- adverse ...
[ { "role": "assistant", "content": "**Answer:** TOM test\nTOM test\nTOM test\ninterrater reliability\nTOM test\nTOM test scores\nintelligence\nWechsler Intelligence Scale for Children\nTOM test scores\nTOM test\n" } ]
TOM test TOM test TOM test interrater reliability TOM test TOM test scores intelligence Wechsler Intelligence Scale for Children TOM test scores TOM test
10100592_participants
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract participant-related spans from the abstract.\n\nInclude spans that describe the patient/population, such as:\n- disease/condition population terms\n- demographic descriptors (for example age/sex g...
[ { "role": "assistant", "content": "**Answer:** tumors of hematopoietic organs .\npatients with tumors of hematopoietic organs\nmultiple institutions using a central registration system\n" } ]
tumors of hematopoietic organs . patients with tumors of hematopoietic organs multiple institutions using a central registration system
10100592_interventions
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract intervention/comparator-related spans from the abstract.\n\nInclude spans that describe treatment arms or comparators, such as:\n- drug/device/procedure/intervention names\n- comparator/control/pl...
[ { "role": "assistant", "content": "**Answer:** granisetron injection\ngranisetron injection\nmultidrug combined cancer chemotherapy excluding cisplatin\ngranisetron\n" } ]
granisetron injection granisetron injection multidrug combined cancer chemotherapy excluding cisplatin granisetron
10100592_outcomes
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract outcome-related spans from the abstract.\n\nInclude spans that describe measured endpoints/results concepts, such as:\n- named outcomes/endpoints\n- symptom scores or clinical measures\n- adverse ...
[ { "role": "assistant", "content": "**Answer:** appetite\nnumber of episodes of vomiting , the severity of nausea\nclinical efficacy\nefficacy in patients\n" } ]
appetite number of episodes of vomiting , the severity of nausea clinical efficacy efficacy in patients
10148879_participants
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract participant-related spans from the abstract.\n\nInclude spans that describe the patient/population, such as:\n- disease/condition population terms\n- demographic descriptors (for example age/sex g...
[ { "role": "assistant", "content": "**Answer:** during labor .\nEighty healthy women beginning active labor ( cervical dilation 4 cm ) at term were assigned to receive fentanyl intravenously by either patient-controlled administration ( n=37 ) or nurse administration on demand ( n=43 )\n" } ]
during labor . Eighty healthy women beginning active labor ( cervical dilation 4 cm ) at term were assigned to receive fentanyl intravenously by either patient-controlled administration ( n=37 ) or nurse administration on demand ( n=43 )
10148879_interventions
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract intervention/comparator-related spans from the abstract.\n\nInclude spans that describe treatment arms or comparators, such as:\n- drug/device/procedure/intervention names\n- comparator/control/pl...
[ { "role": "assistant", "content": "**Answer:** patient-controlled and nurse-administered analgesia\nfentanyl citrate\npatient-controlled administration of fentanyl\nadministration by nurses on request\nfentanyl\npatient-controlled administration\nnurse administration on demand\nadministration by the patient...
patient-controlled and nurse-administered analgesia fentanyl citrate patient-controlled administration of fentanyl administration by nurses on request fentanyl patient-controlled administration nurse administration on demand administration by the patient administration by the nurses
10148879_outcomes
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract outcome-related spans from the abstract.\n\nInclude spans that describe measured endpoints/results concepts, such as:\n- named outcomes/endpoints\n- symptom scores or clinical measures\n- adverse ...
[ { "role": "assistant", "content": "**Answer:** Pain intensity measurements\ndegree of analgesia\ntime between requesting analgesia and vaginal delivery\nMaternal oversedation and vomiting\nNeonatal naloxone therapy\numbilical serum levels of fentanyl\npostnatal neuroadaptive testing\ndrug use\nimproving pai...
Pain intensity measurements degree of analgesia time between requesting analgesia and vaginal delivery Maternal oversedation and vomiting Neonatal naloxone therapy umbilical serum levels of fentanyl postnatal neuroadaptive testing drug use improving pain relief avoiding drowsiness
10155556_participants
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract participant-related spans from the abstract.\n\nInclude spans that describe the patient/population, such as:\n- disease/condition population terms\n- demographic descriptors (for example age/sex g...
[ { "role": "assistant", "content": "**Answer:** polyarteritis nodosa\nChurg-Strauss syndrome\npolyarteritis nodosa\nPAN\nChurg-Strauss syndrome\nCSS\n236\n71\nwithout HBV markers\nwith HBV markers\n78\nwithout HBV markers\n33\nPAN\nHBV\n56\nsevere PAN without HBV markers\nPAN\n" } ]
polyarteritis nodosa Churg-Strauss syndrome polyarteritis nodosa PAN Churg-Strauss syndrome CSS 236 71 without HBV markers with HBV markers 78 without HBV markers 33 PAN HBV 56 severe PAN without HBV markers PAN
10155556_interventions
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract intervention/comparator-related spans from the abstract.\n\nInclude spans that describe treatment arms or comparators, such as:\n- drug/device/procedure/intervention names\n- comparator/control/pl...
[ { "role": "assistant", "content": "**Answer:** cyclophosphamide\nplasma exchanges\nprednisone and PE\nprednisone\nsteroid and immunosuppressive therapy\nshort-term steroid therapy and PE\nanti-viral therapy\nprednisone in association with CYC\nanti-viral agents and PE\nPE\nPE\nPE\n" } ]
cyclophosphamide plasma exchanges prednisone and PE prednisone steroid and immunosuppressive therapy short-term steroid therapy and PE anti-viral therapy prednisone in association with CYC anti-viral agents and PE PE PE PE
10155556_outcomes
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract outcome-related spans from the abstract.\n\nInclude spans that describe measured endpoints/results concepts, such as:\n- named outcomes/endpoints\n- symptom scores or clinical measures\n- adverse ...
[ { "role": "assistant", "content": "**Answer:** efficacy\nsubsequent survival\nevolution of PAN\netiological agent of the vasculitis .\nprognosis\ncontrol of the disease\ncontrol of the disease\ninfectious side effects\neffective\nlength of HBV infection\nseroconversion rate .\n" } ]
efficacy subsequent survival evolution of PAN etiological agent of the vasculitis . prognosis control of the disease control of the disease infectious side effects effective length of HBV infection seroconversion rate .
10172265_participants
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract participant-related spans from the abstract.\n\nInclude spans that describe the patient/population, such as:\n- disease/condition population terms\n- demographic descriptors (for example age/sex g...
[ { "role": "assistant", "content": "**Answer:** acute stroke\nstroke\n" } ]
acute stroke stroke
10172265_interventions
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract intervention/comparator-related spans from the abstract.\n\nInclude spans that describe treatment arms or comparators, such as:\n- drug/device/procedure/intervention names\n- comparator/control/pl...
[ { "role": "assistant", "content": "**Answer:** Thrombolysis\nthrombolysis\n" } ]
Thrombolysis thrombolysis
10172265_outcomes
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract outcome-related spans from the abstract.\n\nInclude spans that describe measured endpoints/results concepts, such as:\n- named outcomes/endpoints\n- symptom scores or clinical measures\n- adverse ...
[ { "role": "assistant", "content": "**Answer:** death\ndisability\nmortality\ndisability\nmortality in myocardial infarction\nrecanalisation\nmortality\nsevere invalidity\n" } ]
death disability mortality disability mortality in myocardial infarction recanalisation mortality severe invalidity
10188144_participants
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract participant-related spans from the abstract.\n\nInclude spans that describe the patient/population, such as:\n- disease/condition population terms\n- demographic descriptors (for example age/sex g...
[ { "role": "assistant", "content": "**Answer:** chronic idiopathic urticaria\nchronic idiopathic urticaria ( CIU )\n247\nCIU\n" } ]
chronic idiopathic urticaria chronic idiopathic urticaria ( CIU ) 247 CIU
10188144_interventions
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract intervention/comparator-related spans from the abstract.\n\nInclude spans that describe treatment arms or comparators, such as:\n- drug/device/procedure/intervention names\n- comparator/control/pl...
[ { "role": "assistant", "content": "**Answer:** mizolastine\nplacebo-controlled\nloratadine\nMizolastine\nmizolastine with loratadine\nplacebo\nplacebo\nmizolastine\nloratadine\nplacebo\nMizolastine\nloratadine\nmizolastine and loratadine\nplacebo\nmizolastine\nloratadine\nplacebo\nplacebo\nmizolastine\nlora...
mizolastine placebo-controlled loratadine Mizolastine mizolastine with loratadine placebo placebo mizolastine loratadine placebo Mizolastine loratadine mizolastine and loratadine placebo mizolastine loratadine placebo placebo mizolastine loratadine placebo mizolastine loratadine placebo placebo mizolastine or loratadin...
10188144_outcomes
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract outcome-related spans from the abstract.\n\nInclude spans that describe measured endpoints/results concepts, such as:\n- named outcomes/endpoints\n- symptom scores or clinical measures\n- adverse ...
[ { "role": "assistant", "content": "**Answer:** Efficacy and safety\nrelieved symptoms of CIU\nseverity of pruritus ( visual analogue score ( VAS ) assessed by patients )\nepisodes of urticaria\nAngioedema\nOverall tolerability\neffects on cardiac repolarisation\neffective and well tolerated\nurticarial symp...
Efficacy and safety relieved symptoms of CIU severity of pruritus ( visual analogue score ( VAS ) assessed by patients ) episodes of urticaria Angioedema Overall tolerability effects on cardiac repolarisation effective and well tolerated urticarial symptoms
10190267_participants
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract participant-related spans from the abstract.\n\nInclude spans that describe the patient/population, such as:\n- disease/condition population terms\n- demographic descriptors (for example age/sex g...
[ { "role": "assistant", "content": "**Answer:** Rett syndrome :\nfemale patients .\n" } ]
Rett syndrome : female patients .
10190267_interventions
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract intervention/comparator-related spans from the abstract.\n\nInclude spans that describe treatment arms or comparators, such as:\n- drug/device/procedure/intervention names\n- comparator/control/pl...
[ { "role": "assistant", "content": "**Answer:** L-carnitine\nL-carnitine\nplacebo-controlled\nL-carnitine\nplacebo\nL-carnitine\nL-carnitine\nplacebo\nL-carnitine\nL-carnitine\nL-carnitine\n" } ]
L-carnitine L-carnitine placebo-controlled L-carnitine placebo L-carnitine L-carnitine placebo L-carnitine L-carnitine L-carnitine
10190267_outcomes
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract outcome-related spans from the abstract.\n\nInclude spans that describe measured endpoints/results concepts, such as:\n- named outcomes/endpoints\n- symptom scores or clinical measures\n- adverse ...
[ { "role": "assistant", "content": "**Answer:** the Rett Syndrome Motor Behavioral Assessment\nthe Hand Apraxia Scale\nthe\nPatient Well-Being Index\nwell-being\nHand Apraxia Scale\n" } ]
the Rett Syndrome Motor Behavioral Assessment the Hand Apraxia Scale the Patient Well-Being Index well-being Hand Apraxia Scale
10194485_participants
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract participant-related spans from the abstract.\n\nInclude spans that describe the patient/population, such as:\n- disease/condition population terms\n- demographic descriptors (for example age/sex g...
[ { "role": "assistant", "content": "**Answer:** healthy volunteers and patients who are post-thrombotic .\n" } ]
healthy volunteers and patients who are post-thrombotic .
10194485_interventions
[ { "role": "user", "content": "You are an expert biomedical annotator for PICO span extraction.\n\nTask: extract intervention/comparator-related spans from the abstract.\n\nInclude spans that describe treatment arms or comparators, such as:\n- drug/device/procedure/intervention names\n- comparator/control/pl...
[ { "role": "assistant", "content": "**Answer:** High-pressure , rapid-inflation pneumatic compression\nduplex ultrasound scanning\nThree high-pressure , rapid-compression devices and two standard , low-pressure\nslow-inflation compression devices\n" } ]
High-pressure , rapid-inflation pneumatic compression duplex ultrasound scanning Three high-pressure , rapid-compression devices and two standard , low-pressure slow-inflation compression devices
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EBM-NLP

Dataset Description

Links
Homepage: Huggingface
Original Repository: Github
Paper: arXiv
Contact (Main Original Author): Benjamin Nye (nye.b@husky.neu.edu)
Contact (Curator): Artur Guimarães (artur.guimas@gmail.com)

Dataset Summary

We present a corpus of 5,000 richly annotated abstracts of medical articles describing clinical randomized controlled trials. Annotations include demarcations of text spans that describe the Patient population enrolled, the Interventions studied and to what they were Compared, and the Outcomes measured (the ‘PICO’ elements). These spans are further annotated at a more granular level, e.g., individual interventions within them are marked and mapped onto a structured medical vocabulary. We acquired annotations from a diverse set of workers with varying levels of expertise and cost. We describe our data collection process and the corpus itself in detail. We then outline a set of challenging NLP tasks that would aid searching of the medical literature and the practice of evidence-based medicine.

Data Instances

{
  'TO:DO': ...,
  ...
}

Data Fields

TO:DO

Additional Information

Dataset Curators

Original Paper

Huggingface Curator

Licensing Information

CC BY-SA 4.0

Citation Information

@inproceedings{nye2018corpus,
  title={A corpus with multi-level annotations of patients, interventions and outcomes to support language processing for medical literature},
  author={Nye, Benjamin and Li, Junyi Jessy and Patel, Roma and Yang, Yinfei and Marshall, Iain and Nenkova, Ani and Wallace, Byron C},
  booktitle={Proceedings of the 56th Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers)},
  pages={197--207},
  year={2018}
}

Contributions

Thanks to araag2 for adding this dataset.

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Collection including araag2/EBM_NLP

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