Title stringlengths 0 905 | Abstract stringlengths 0 11.3k | Container_Title stringlengths 0 126 | Subject listlengths 1 13 |
|---|---|---|---|
Élections, dumping politique et populisme : Quand l’Algérie triomphe du « printemps arabe » | [
"Geology",
"Ocean Engineering",
"Water Science and Technology"
] | ||
Influence of different shrinking temperatures and vacuum conditions on the ability of psychrotrophic Clostridium to cause ‘blown pack’ spoilage in chilled vacuum-packaged beef | [
"Food Science"
] | ||
Modelagem da infiltração em solos com encrostamento superficial. Parte II: condutividade hidráulica variando no tempo | RESUMO Este trabalho objetivou avaliar o desempenho do modelo de Green-Ampt-Mein-Larson (GAML) na simulação do processo de infiltração em solos com encrostamento superficial. Os ensaios de infiltração foram realizados num Cambissolo com a utilização de simulador de chuvas, em solo nu. O valor da condutividade hidráulica na zona de transmissão (Kt) foi considerado igual a Kt* que, por sua vez, é igual à taxa de infiltração estável (Tie) multiplicada pelo fator f, que representa o decaimento da Tie em função da energia cinética acumulada da chuva (Ec), ou seja, o valor de Kt variando ao longo do tempo. O modelo GAML com o valor de Kt constante ao longo do tempo não obteve bom desempenho superestimando, na maioria dos casos, os valores da taxa de infiltração (Ti) enquanto com o uso de Kt* o modelo apresentou bom desempenho, em que os melhores resultados foram obtidos com a combinação de Kt* com o potencial matricial (jf) calculado com uso da equação de Cecílio et al. (2007). O modelo de GAML com valor da condutividade hidráulica na zona de transmissão (Kt) variando no tempo apresentou bons resultados na simulação do processo de infiltração em solos sujeitos ao encrostamento superficial. | [
"Agricultural and Biological Sciences (miscellaneous)",
"Agronomy and Crop Science",
"Environmental Engineering"
] | |
Theoretical Analyses of Cantilever Oscillation for Dynamic Atomic Force Microscopy in Liquids | [
"Physics and Astronomy (miscellaneous)"
] | ||
Pollard, Porcelain Painter | [
"Library and Information Sciences",
"Literature and Literary Theory",
"Linguistics and Language",
"Language and Linguistics"
] | ||
Prevalence of Coronary Artery Disease, Atherothrombotic Brain Infarction, and Peripheral Arterial Disease: Associated Risk Factors in Older Hispanics in an Academic Hospital-Based Geriatrics Practice | [
"Geriatrics and Gerontology"
] | ||
Chronique de l'A.E.D. (Association des experts-démographes et diplômés de démographie générale) | [
"Demography"
] | ||
Radar Signal Processing in Instrumentation and Measurement Technology | IEEJ Transactions on Fundamentals and Materials | [
"Electrical and Electronic Engineering"
] | |
Mesenteric Venous Thrombosis | [
"Radiology, Nuclear Medicine and Imaging"
] | ||
Identification of a novel HLA‐DPB1 allele, HLA‐DPB1*612:01 , in a Chinese individual | [
"Genetics",
"Immunology",
"Immunology and Allergy"
] | ||
Bioequivalence of Docosahexaenoic Acid from Different Algal Oils in Capsules and in a DHA-Fortified Food | Lipids | [
"Cell Biology",
"Organic Chemistry",
"Biochemistry"
] | |
Potential distribution on the surface of a thin cylindrical superconducting film of In-Pb alloy | [
"Condensed Matter Physics",
"Electronic, Optical and Magnetic Materials"
] | ||
Anne Digby and John Stewart (eds.), Gender, Health and Welfare, Routledge, London, 1996, 239 pp., hard £40.00. | [
"Management, Monitoring, Policy and Law",
"Public Administration",
"Social Sciences (miscellaneous)"
] | ||
Masthead | [
"Animal Science and Zoology"
] | ||
Elevated Natriuretic Peptides in Patients With Severe or Critical COVID-19: A Meta-Analysis | Background The worldwide COVID-19 pandemic caused by SARS-CoV-2 has resulted in an extraordinary increase in the number of patients who are severely critically ill. For many of these patients, cardiovascular risk factors are key contributors to the development of severe illness. Laboratory markers for cardiac damage and failure, such as natriuretic peptides, are reported to be elevated in patients with severe COVID-19. Methods We conducted a systematic review and meta-analysis to compare natriuretic peptide levels in patients with severe COVID-19 vs those with nonsevere COVID-19. PubMed and medRxiv were searched through April 7, 2020. The outcome of interest was the difference in B-type natriuretic peptide (BNP) or N-terminal-proBNP levels in patients with severe vs nonsevere COVID-19. Results We identified 9 retrospective cohort studies that had a total of 1,575 patients with COVID-19 who had their natriuretic peptides measured and were classified by disease severity. All studies were conducted in China. Patients with severe COVID-19 had significantly higher BNP levels than patients with nonsevere COVID-19 (mean difference, 69.56 pg/mL; 95% CI, 1.77–137.35 pg/mL; P = .04, I2 = 83%). Similarly, patients with severe COVID-19 had significantly higher N-terminal-proBNP levels than patients with nonsevere COVID-19 (mean difference, 518.65 pg/mL; 95% CI, 152.40–884.90 pg/mL; P = .006, I2 = 86%). Conclusions In this study, Chinese patients with severe COVID-19 had higher natriuretic peptide levels than those with nonsevere COVID-19. Studies from all countries affected by the virus will help to further delineate whether the cause is directly or indirectly of cardiac origin and whether preexisting heart failure has an influence on this disparity. | Texas Heart Institute Journal | [
"Cardiology and Cardiovascular Medicine"
] |
Liver Gas Gangrene after Biliary Surgery | [
"Gastroenterology",
"Hepatology"
] | ||
Commentary by Ronald Britton | [
"Neuropsychology and Physiological Psychology"
] | ||
A self report measure of affective lability | Journal of Neurology, Neurosurgery & Psychiatry | [
"Psychiatry and Mental Health",
"Neurology (clinical)",
"Surgery"
] | |
Claiming health in food products | [
"Nutrition and Dietetics",
"Food Science"
] | ||
Age-related effects on markers of inflammation and cartilage metabolism in response to an intra-articular lipopolysaccharide challenge in horses | [
"Genetics",
"Animal Science and Zoology",
"Food Science"
] | ||
Jackpot by Nic Stone | [
"Community and Home Care"
] | ||
Therapeutic plasma exchange in neurology: 2012 | [
"Hematology"
] | ||
Afwachten bij atypische angina pectoris en een negatief inspanningselektrocardiogram gerechtvaardigdangina pectoris elektrocardiografie hart- en vaatziekten | [
"Family Practice"
] | ||
Photomodulation of the Melanocyte Cell Cycle by Indoleamines | Neurosignals | [
"Cellular and Molecular Neuroscience",
"Developmental Neuroscience",
"Neurology"
] | |
Adult Children of Alcoholics and Chronic Career Indecision | [
"Organizational Behavior and Human Resource Management",
"Applied Psychology"
] | ||
L'aspect progressif en coréen | [
"Linguistics and Language",
"Language and Linguistics"
] | ||
A [4,5-3H]lysine:[14C]lysine dual-label method to measure lysine hydroxylation in collagen | [
"Cell Biology",
"Molecular Biology",
"Biochemistry",
"Biophysics"
] | ||
Cities without Cavities: Democracy, Risk, and Public Health | This essay examines the history of fluoride debates in four Canadian cities. It argues that fluoride’s opponents were primarily motivated by what they saw as the health and environmental risks of adding fluoride to the water supply. They also believed that fluoridating the public water supply was a fundamental violation of civil liberties. The fluoride debates have much to teach us about how people evaluate potential health risks and how they respond to state interventions in the field of public health. | Journal of Canadian Studies | [
"History",
"Cultural Studies"
] |
Book Notice | [
"Insect Science",
"Ecology, Evolution, Behavior and Systematics"
] | ||
Poultry and fish intake and risk of esophageal cancer: A meta-analysis of observational studies | Asia-Pacific Journal of Clinical Oncology | [
"Oncology"
] | |
Nicke(II) halide complexes with hypoxanthine and xanthine | [
"Materials Chemistry",
"Metals and Alloys",
"Inorganic Chemistry"
] | ||
Fenestrated/Branched Endovascular Repair for Complex Aortic Aneurysms Among Standard and High-risk Patients for Open Repair | [
"Cardiology and Cardiovascular Medicine",
"Surgery"
] | ||
Bipolar II Disorder: Modelling, Measuring and Managing | The Journal of Clinical Psychiatry | [
"Psychiatry and Mental Health"
] | |
Re | [
"Dermatology",
"Surgery"
] | ||
Two Cases of General Chronic Proctitis | [
"Energy Engineering and Power Technology",
"Fuel Technology"
] | ||
The lower vitamin C plasma concentrations in elderly men compared with elderly women can partly be attributed to a volumetric dilution effect due to differences in fat-free mass | Women show higher vitamin C plasma concentrations than men, but the reasons for this observation still require elucidation. The objective of the present study was to investigate whether sex differences in vitamin C plasma concentrations are present in elderly subjects and whether these differences are due to sex-specific lifestyles, total antioxidant status (TAOS) and/or body composition. Fasting plasma concentrations of vitamin C were assessed by photometric detection in a cross-sectional study of 181 women and eighty-nine men aged 62–92 years. Body composition was determined by bioelectrical impedance analysis. Vitamin C intake was assessed with a 3 d estimated dietary record. Stepwise multiple regression analyses were performed to investigate whether sex is an independent predictor of vitamin C plasma concentrations by controlling for age, vitamin C intake, lifestyle factors, TAOS and body composition. Women showed higher vitamin C plasma concentrations than men (76 v. 62 μmol/l, P | [
"Nutrition and Dietetics",
"Medicine (miscellaneous)"
] | |
Schwarzacher T, Heslop-Harrison JS. 2000. Practical in situ hybridisation. 1st edn. 203 pp. Oxford: Bios Scientific Publishers. £21.95 (softback). | Annals of Botany | [
"Plant Science"
] | |
Europe without Socialism? | [
"Literature and Literary Theory",
"Visual Arts and Performing Arts",
"Cultural Studies"
] | ||
Weak and Strong Convergence Theorems for Strictly Pseudononspreading Mappings and Equilibrium Problem in Hilbert Spaces | The purpose of this paper is to propose an iterative algorithm for equilibrium problem and a class of strictly pseudononspreading mappings which is more general than the class of nonspreading mappings studied recently in Kurokawa and Takahashi (2010). We explored an auxiliary mapping in our theorems and proofs and under suitable conditions, some weak and strong convergence theorems are proved. The results presented in the paper extend and improve some recent results announced by some authors. | Abstract and Applied Analysis | [
"Applied Mathematics",
"Analysis"
] |
A Yuwipi Ceremony at Pine Ridge | [
"Anthropology"
] | ||
Role of angiotensin II type I receptor agonistic autoantibodies (AT1-AA) in preeclampsia | Current Opinion in Pharmacology | [
"Drug Discovery",
"Pharmacology"
] | |
Design and evaluation of pressure and electrocardiographic modules embedded in a Cardiac Hemodynamic Monitor | [
"Electrical and Electronic Engineering"
] | ||
Front cover | Dalton Transactions | [
"Inorganic Chemistry"
] | |
Generalization of Higuchi's conditions for Love waves propagating through two welded quarter-spaces with two surface layers on each | abstract Higuchi (1932) considered a medium consisting of two quarter-spaces in welded contact, each having a single homogeneous layer of the same thickness overlying a homogeneous half-space, and gave conditions on the rigidities and densities of the two layers and two half-spaces in such a way that the plane Love waves normally incident on the vertical plane generate only reflected and transmitted Love waves without mode conversion or body-wave scattering. In this paper, we generalize Higuchi's results to two layers overlying a half-space divided by a vertical plane. On one side of the vertical plane, the shear velocities and rigidities for the top and the bottom surface layers, and for the half-space are β1, μ1, β2(>β1), μ2(>μ1), and β3(>β2), μ3(>μ2), respectively. On the other side, the corresponding shear velocities and rigidities for the two layers and the half-space are given by the primed quantities with β3′ > β2′ > β1′ and μ3′ > μ2′ > μ1′. We show that if the following conditions are satisfied 1 β 1 2 − 1 β 1 ' 2 = 1 β 2 2 − 1 β 2 ' 2 = 1 β 3 2 − 1 β 3 ' 22 and μ 1 μ 1 ' = μ 2 μ 2 ' = μ 3 μ 3 ' then plane Love waves normally incident on the vertical plane generate only reflected and transmitted Love waves without mode conversion or body-wave scattering. These conditions for the special case under consideration provide a valuable check for various analytical and numerical approximations which ignore the body-wave contributions in similar diffraction problems. | Bulletin of the Seismological Society of America | [
"Geochemistry and Petrology",
"Geophysics"
] |
The susceptibility of Atlantic salmon fry to freshwater infectious pancreatic necrosis is largely explained by a major QTL | [
"Genetics (clinical)",
"Genetics"
] | ||
Modelling two-layer nanofluid flow in a micro-channel with electro-osmotic effects by means of Buongiorno’s mode | Applied Mathematics and Mechanics | [
"Applied Mathematics",
"Mechanical Engineering",
"Mechanics of Materials"
] | |
Anesthesiology and the Elderly Patient: Are We Ready for the Challenge? | Anesthesiology | [
"Anesthesiology and Pain Medicine"
] | |
Recurrent thromboembolic events after ischemic stroke in patients with cancer | [
"Neurology (clinical)"
] | ||
TAVI for Pure Native Aortic Regurgitation: Are We There Yet? | Treatment of degenerative aortic stenosis has been transformed by transcatheter aortic valve implantation (TAVI) over the past 10–15 years. The success of various technologies has led operators to attempt to broaden the indications, and many patients with native valve aortic regurgitation have been treated ‘off label’ with similar techniques. However, the alterations in the structure of the valve complex in pure native aortic regurgitation are distinct to those in degenerative aortic stenosis, and there are unique challenges to be overcome by percutaneous valves. Nevertheless some promise has been shown with both non-dedicated and dedicated devices. In this article, the authors explore some of these challenges and review the current evidence base for TAVI for aortic regurgitation. | [
"Cardiology and Cardiovascular Medicine"
] | |
Evolução geoquímica e mineralógica em perfis de alteração sobre rochas serpentinizadas no sudoeste de Minas Gerais | Estudou-se a evolução geoquímica e mineralógica em três perfis distintos de alteração de rochas serpentinizadas que ocorrem nas imediações dos municípios de Alpinópolis e Fortaleza de Minas, no sudoeste do Estado de Minas Gerais, sob regimes de umidade e de temperatura údico e térmico, respectivamente. Nas condições atuais, o grau de evolução química e mineralógica é moderado em relação ao desenvolvido sobre outros tipos de rochas básicas e ultrabásicas da mesma área, caracterizando-se por uma importante perda de Na e Mg e, em menor proporção, de Ca e Si. O Al (localmente também o Fe) é o elemento menos móvel dos sistemas. O K é escasso no material de origem e nas zonas de alteração, e ocorre enriquecimento desse elemento nos horizontes superficiais por aporte externo. Os minerais primários mais facilmente intemperizáveis, como o talco, a tremolita e a clorita trioctaédrica, são abundantes ainda na fração argila desses solos tropicais com composição mineralógica pouco comum, mas são todos termodinamicamente instáveis. Do ponto de vista geoquímico, o processo de alteração atual pode ser definido como uma bissialitização, que pode coincidir com ferruginização, com formação de minerais trioctaédricos secundários por transformação direta de estrutura e também por neoformação, todos coexistindo com os minerais primários residuais. No entanto, as fases de maior evolução, em volumes com drenagem mais eficiente, tendem à monossialitização, com formação de caulinitas de diferentes graus de cristalinidade. A assembléia mineralógica existente evidencia a metaestabilidade e o caráter incipiente do sistema pedogenético. | [
"Soil Science",
"Agronomy and Crop Science"
] | |
Probabilistic Combination of Forces in Tension Leg Platform Tethers | [
"Mechanical Engineering",
"Mechanics of Materials",
"Building and Construction",
"Civil and Structural Engineering"
] | ||
A Working Memory Workout: How to Expand the Focus of Serial Attention From One to Four Items in 10 Hours or Less. | Journal of Experimental Psychology: Learning, Memory, and Cognition | [
"Linguistics and Language",
"Language and Linguistics",
"Experimental and Cognitive Psychology"
] | |
Mapping the Transmississippi West, 1540-1861. Volume II, From Lewis and Clark to Fremont, 1804-1845 | [
"Museology",
"Archeology",
"History"
] | ||
In the Name of Human Rights: Global Organizations and Participating Citizens | [
"Political Science and International Relations",
"Geography, Planning and Development"
] | ||
Simultaneous Localization and Mapping in a Camera Network - Note from the publisher | [
"Computer Science Applications",
"Hardware and Architecture",
"Human-Computer Interaction",
"Software",
"Control and Systems Engineering"
] | ||
Influence of a Preadmission Procedure-Specific Consent Document on Patient Recall of Informed Consent at 4 Weeks After Total Hip Replacement: A Randomized Controlled Trial | [
"Public Health, Environmental and Occupational Health",
"Leadership and Management"
] | ||
Reducing the Cost of Consumables Used for ABI 310 Genetic Analyzer | [
"Cell Biology",
"Molecular Biology",
"Biochemistry",
"Biophysics"
] | ||
The influence of polyhydroxylated compounds on a hydrated phospholipid bilayer: a molecular dynamics study | Molecular Simulation | [
"Condensed Matter Physics",
"Modeling and Simulation",
"Information Systems"
] | |
Penetration into a sand sediment of difference‐frequency sound generated by a parametric array | The Journal of the Acoustical Society of America | [
"Acoustics and Ultrasonics",
"Arts and Humanities (miscellaneous)"
] | |
TOF-SIMS Analysis with High Lateral and High Mass Resolution in Parallel | [
"Instrumentation"
] | ||
Favorable Molecular Responses to Imatinib in CML Patients in Early Chronic Phase in Comparison to Late Chronic Phase Patients after Treatment with Hydroxyurea and Interferon. | Abstract Peripheral blood samples from 70 patients treated with imatinib were regularly sent to us for the determination of bcr-abl transcript levels by a standardized quantitative real-time PCR (TaqMan®). 45 patients with early chronic phase CML were treated with imatinib as a first line therapy and 25 patients in late chronic phase received imatinib as a second line therapy after hydroxyurea plus interferon. The median pre-treatment time with hydroxyurea plus interferon in these late chronic patients was 43 months (6 – 130). The median follow-up was 18.4 months (1–51) for first line patients and 18.0 months (1–48) for second line patients. Patients received a median dosage between 400–600 mg imatinib in both groups. At the time of diagnosis the median bcr-abl/abl ratio was 248 % (26–460%, SD: 148%) in patient receiving imatinib as a first line treatment. Patients receiving imatinib as second line treatment had a median bcr-abl/abl ratio of 24,84% (1–256%, SD: 78%) just before the imatinib treatment was initiated. Early chronic phase CML patients treated with imatinib as a first line therapy showed a strong biphasic decay of their bcr-abl transcript with a fast reduction between 1-2-log during the first 6–9 months followed by a slower rate of reduction afterwards. A bcr-abl/abl ratio <0.1% could be observed in 19/51 (37%) patients and in 12/51 (23%) patients a bcr-abl/abl ratio < 0.01% was found. After 18 months of therapy the median reduction of bcr-abl was about 2.5-log, after 36 months about 3-log. 12/51 (23%) patients showed a suboptimal response or had a subsequent increase of their bcr-abl transcript levels. Best responding patients could be identified by a >2-log reduction after 6 months and > 3-log reduction after 18 months of therapy. In late chronic phase CML patients pre-treated with hydroxyurea and interferon the overall median decrease of bcr-abl transcript levels was about 1-log after a median follow-up of 18 as well as after 36–48 months. Obviously, there are at least three subgroups of patients with a different molecular response. We identified 7/25 (28%) patients with no significant reduction of bcr-abl transcripts after 18 months as well as after 36 months of imatinib therapy. In contrast, another group of 4/25 (16%) patients showed a 2-log reduction of bcr-abl/abl ratio after 18 months with a subsequent reduction of 3-log after 36 months. Within the largest group of 14/25 (56%) patients a 1-log reduction after 18 months and a 1-2-log reduction after 36 months was observed. No patient had > 3-log reduction within the whole group of 25 late chronic phase patients. The reduction of bcr-abl transcript levels as a result of imatinib therapy is significantly superior in CML patients receiving imatinib as first line treatment for CML in early chronic phase compared to patients treated with imatinib after a long term pre-treatment with hydroxyurea and interferon. | [
"Cell Biology",
"Hematology",
"Immunology",
"Biochemistry"
] | |
Reinstating the Family: Intergenerational Influence on Assortative Mating in China | [
"Sociology and Political Science",
"Anthropology",
"Demography",
"Gender Studies"
] | ||
Doping effects in thin films of radical phthalocyanines: UPS and conductivity studies | Synthetic Metals | [
"Materials Chemistry",
"Metals and Alloys",
"Mechanical Engineering",
"Mechanics of Materials",
"Condensed Matter Physics",
"Electronic, Optical and Magnetic Materials"
] | |
Characteristics and utilization of biologically aerated filter backwashed sludge | [
"Mechanical Engineering",
"Water Science and Technology"
] | ||
Multibody Structure-and-Motion Segmentation by Branch-and-Bound Model Selection | [
"Computer Graphics and Computer-Aided Design",
"Software"
] | ||
Chart IV. Departure of the Mean Temperature from the Normal, January, 1915 | [
"Atmospheric Science"
] | ||
The Struggle to Develop a “Research Culture” in a Developing Country | TESOL Quarterly | [
"Linguistics and Language",
"Language and Linguistics",
"Education"
] | |
Investigation of the expression of P-element-induced wimpy testis-interacting RNAs in human acute myeloid leukemia | [
"Genetics (clinical)",
"Genetics"
] | ||
Les mesures thérapeutiques en droit pénal suisse | [
"Psychiatry and Mental Health",
"Clinical Psychology",
"Psychiatric Mental Health"
] | ||
Integrally hydrophobic cementitious composites made with waste amorphous carbon powder | [
"Building and Construction",
"Civil and Structural Engineering"
] | ||
MERCURY CONTAMINATION IN FREE-RANGING GREAT EGRET NESTLINGS (ARDEA ALBUS) FROM SOUTHERN FLORIDA, USA | [
"Health, Toxicology and Mutagenesis",
"Environmental Chemistry"
] | ||
Technique chirurgicale : conversion d’une sleeve gastrectomie en Roux-en-Y gastrique bypass par voie cœlioscopique | [
"Surgery"
] | ||
An improved general synthesis of 4-aryl-5-pyrimidinecarboxylates | [
"Organic Chemistry"
] | ||
Microbial fuel cell cathodes: from bottleneck to prime opportunity? | Microbial fuel cells that can generate energy out of wastewaters are close to pilot scale testing. As such, MFC technology is complementary to methane generation due to the possibility to rapidly convert organic acids, polish effluents and work at low substrate concentrations. The main bottleneck perceived at the moment is the cathodic electron transfer. A variety of catalysts has been investigated for the direct transfer of electrons from the cathode to oxygen in the air. Overlooked in this context were bacteria. Bacteria could indeed be worthwhile to replace chemical catalysts. Moreover, their versatility enables us to not only target at oxygen, but also at nitrous oxides and contaminants as possible drivers of electricity generation, nutrient removal and bioremediation. This paper addresses several recent developments in MFC cathode research, and demonstrates that energy generation is but an aspect of this versatile technology. | Water Science and Technology | [
"Water Science and Technology",
"Environmental Engineering"
] |
The Economic Outlook for Textiles and Clothing in the 1990s: Developments in the Textile and Clothing Industry in Japan | [
"Industrial and Manufacturing Engineering",
"Polymers and Plastics",
"Materials Science (miscellaneous)"
] | ||
Spatiotemporal Variation of Risk Preceding Crashes on Freeways | Research into the application of freeway loop detector data for traffic safety has gained momentum in recent years. The incompleteness of data from loop detectors has been a common problem in both the development and the implementation of models. The effect of individual crash precursors, obtained one at a time from a series of loop detectors, on relative risk of crash occurrence was examined through within-stratum one-covariate logistic regression models. The hazard ratio (resultant change in log odds of observing a crash by changing the covariate by one unit) was used as the measure of risk. The log of coefficient of variation in speed expressed as percentage, standard deviation of volume, and average occupancy expressed as percentage were found to be the most significant individual covariates affecting the odds of crash occurrence at a crash site. It was also observed that these parameters calculated at a 5-min level (as opposed to a 3-min level) are more significantly associated with crash occurrence. Hazard ratios corresponding to these covariates observed at a series of stations during six 5-min slices were plotted as a contour variable. The location and time of measurements of these parameters with respect to the location and time of the crash were used as ordinate and abscissa, respectively, in the contour plots depicting spatiotemporal variation of crash risk. The chart corresponding to the log of coefficient of variation in speed demonstrated the most clear patterns of increasing risk as the time and location of the crash are approached. On the basis of these spatiotemporal patterns, a methodology with which to identify freeway black spots in real time is proposed. This information could be used by traffic management centers to take preventive measures to avoid crashes or to prepare law enforcement and emergency vehicles for the impending situation. | [
"Mechanical Engineering",
"Civil and Structural Engineering"
] | |
Application of Cavitation Ozonation Process on Recalcitrant Organic Matter Degradation from Stabilized Landfill Leachate | [
"Management of Technology and Innovation",
"Strategy and Management"
] | ||
Corrosion of Ba1−xSrxCo1−yFeyO3−δ and La0.3Ba0.7Co0.2Fe0.8O3−δ materials for oxygen separating membranes under Oxycoal conditions | [
"Filtration and Separation",
"Physical and Theoretical Chemistry",
"Biochemistry"
] | ||
Effect of Water Roux Starter (Tangzhong) on Texture and Consumer Acceptance of Rice Pan Bread | Journal of Texture Studies | [
"Pharmaceutical Science",
"Food Science"
] | |
BTLA-HVEM Couple in Health and Diseases: Insights for Immunotherapy in Lung Cancer | Lung cancer is the leading cause of cancer deaths worldwide. Immunotherapies (IT) have been rapidly approved for lung cancer treatment after the spectacular results in melanoma. Responses to the currently used checkpoint inhibitors are strikingly good especially in metastatic diseases. However, durable responses are observed in only 25% of cases. Consequently, there is an urgent need for new immunotherapy targets. Among the multiple checkpoints involved in the tumor immune escape, the BTLA-HVEM couple appears to be a promising target. BTLA (B- and T- Lymphocyte Attenuator) is a co-inhibitory receptor mainly expressed by B and T cells, repressing the activation signal transduction. BTLA shares similarities with other immune checkpoints such as PD-1 and CTLA-4 which are the targets of the currently used immunotherapies. Furthermore, BTLA expression points out terminally exhausted and dysfunctional lymphocytes, and correlates with lung cancer progression. The ligand of BTLA is HVEM (Herpes Virus Entry Mediator) which belongs to the TNF receptor family. Often described as a molecular switch, HVEM is constitutively expressed by many cells, including cells from tumor and healthy tissues. In addition, HVEM seems to be involved in tumor immuno-evasion, especially in lung tumors lacking PD-L1 expression. Here, we propose to review the role of BTLA-HVEM in immuno-escape in order to highlight its potential for designing new immunotherapies. | [
"Cancer Research",
"Oncology"
] | |
The source dilemma hypothesis: Perceptual uncertainty contributes to musical emotion | [
"Cognitive Neuroscience",
"Linguistics and Language",
"Developmental and Educational Psychology",
"Language and Linguistics",
"Experimental and Cognitive Psychology"
] | ||
Does reflective practice have relevance for innovation in public relations? | Writers such as Schön and Argyris have been influential in our understanding of how people and organisations learn. They contend that “real” learning only takes place when we challenge assumptions and the taken‐for‐granted aspects of everyday working life, as well as the values on which these assumptions are based. Further, the ability of learning to learn (or “double‐loop learning” as it is sometimes called) at both an individual and an organisational level is regarded by such writers as the key skill in adapting to a fast‐changing world. With this framework in mind, professional courses such as the Advanced Professional Diploma in Public Relations at Leeds Metropolitan University have incorporated the philosophy of “reflective learning” in assessment. The assessment tool of this type of course is typically a reflective learning assignment where individual learners critically reflect on their own working practice in the light of newly acquired knowledge and skills. The assignment, at least in theory, is not an end in itself but the start of a continuous process of self‐reflection and challenging of assumptions underlying practice in everyday working life. It follows, therefore, that such an approach could have a relevance for innovation in individual working practices. This paper seeks to examine whether reflective learning conducted within an academic setting has a relevance for innovation in public relations. It draws on theories and discussion in the fields of organisational learning; reflective learning and reflective practice; a critical analysis of 25 reflective learning assignments; and six telephone interviews with public relations practitioners who have successfully completed the Advanced Professional Diploma in Public Relations at Leeds Metropolitan University. It is followed by a discussion of the link between their reflective learning and organisational learning, and suggests where innovation is most likely to occur. Finally, implications for academics and practitioners are discussed. | [
"Strategy and Management",
"Communication"
] | |
Monopolar Transurethral Enucleation of Prostatic Adenoma: Preliminary Report | Urology | [
"Urology"
] | |
Perceptual organization deficits in psychotic patients | [
"Biological Psychiatry",
"Psychiatry and Mental Health"
] | ||
Kollektivautobiographien, Wunschautobiographien: Marranenschicksal im deutsch-judischen historischen Roman | The Modern Language Review | [
"Literature and Literary Theory",
"Linguistics and Language",
"Language and Linguistics"
] | |
Magnetic resonance imaging accuracy in assessing tumour down-staging following chemoradiation in rectal cancer | [
"Gastroenterology"
] | ||
Deformation-induced martensitic transformation in 316L stainless steels fabricated by laser powder bed fusion | [
"Mechanical Engineering",
"Mechanics of Materials",
"Condensed Matter Physics"
] | ||
The effect of spin mixing on the quantum Hall effect in graphene | [
"Condensed Matter Physics"
] | ||
Chemical interaction dictated energy level alignment at the N,N′-dipentyl-3,4,9,10-perylenedicarboximide/CH3NH3PbI3 interface | [
"Physics and Astronomy (miscellaneous)"
] | ||
Can tourism development enhance livelihood capitals of rural households? Evidence from Huangshan National Park adjacent communities, China | [
"Pollution",
"Waste Management and Disposal",
"Environmental Chemistry",
"Environmental Engineering"
] | ||
Analysis of the local field effects on voltage measurements with an 'in-lens spectrometer' | Journal of Physics E: Scientific Instruments | [
"Instrumentation"
] | |
The effect of DDAVP and placebo on platelet function and prolonged bleeding time induced by oral acetylsalicylic acid intake on volunteers | Journal of Cardiothoracic and Vascular Anesthesia | [
"Anesthesiology and Pain Medicine",
"Cardiology and Cardiovascular Medicine"
] | |
Power System Topological Observability Using a Direct Graph-Theoretic Approach | [
"Electrical and Electronic Engineering",
"Energy Engineering and Power Technology"
] | ||
The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: therapeutic applications | The proteasome inhibitor PS-341 inhibits nuclear factor-κB (NF-κB) activation, induces apoptosis in cancer cells, including multiple myeloma (MM) cells, and has marked clinical activity as a monotherapy for MM. In this study, we found that subtoxic concentrations of PS-341 potently sensitized MM cell lines and patient cells to DNA-damaging chemotherapeutic agents such as doxorubicin and melphalan, including cells resistant to these drugs and those isolated from a patient who had relapsed after PS-341 monotherapy. Moreover, PS-341 abolished cell adhesion–mediated drug resistance. Using gene expression profiling and proteomic analysis, we demonstrate that PS-341, among its other proapoptotic effects, down-regulates the expression of several effectors involved in the cellular response to genotoxic stress. These data suggest that, in addition to down-regulating the expression of apoptosis inhibitors, PS-341 inhibits genotoxic stress response pathways and thereby restores sensitivity to DNA-damaging chemotherapeutic agents. These studies, therefore, provide the framework for clinical use of this agent in combination with conventional chemotherapy. | [
"Cell Biology",
"Hematology",
"Immunology",
"Biochemistry"
] | |
Spiral Chaos in a Predator-Prey Model | [
"Ecology, Evolution, Behavior and Systematics"
] | ||
Histological observations on the pituitary gland and the glomerular body of the larvae of the marine teleost, Hexagrammos otakii | [
"Cell Biology",
"Histology",
"Pathology and Forensic Medicine"
] | ||
Salt tectonics in the Sivas Basin, Turkey: outstanding seismic analogues from outcrops | First Break | [
"Geophysics"
] | |
Guest Editorial | Journal of Networks | [
"Computer Networks and Communications"
] | |
Organic Cation Transporters in Human Physiology, Pharmacology, and Toxicology | Individual cells and epithelia control the chemical exchange with the surrounding environment by the fine-tuned expression, localization, and function of an array of transmembrane proteins that dictate the selective permeability of the lipid bilayer to small molecules, as actual gatekeepers to the interface with the extracellular space. Among the variety of channels, transporters, and pumps that localize to cell membrane, organic cation transporters (OCTs) are considered to be extremely relevant in the transport across the plasma membrane of the majority of the endogenous substances and drugs that are positively charged near or at physiological pH. In humans, the following six organic cation transporters have been characterized in regards to their respective substrates, all belonging to the solute carrier 22 (SLC22) family: the organic cation transporters 1, 2, and 3 (OCT1–3); the organic cation/carnitine transporter novel 1 and 2 (OCTN1 and N2); and the organic cation transporter 6 (OCT6). OCTs are highly expressed on the plasma membrane of polarized epithelia, thus, playing a key role in intestinal absorption and renal reabsorption of nutrients (e.g., choline and carnitine), in the elimination of waste products (e.g., trimethylamine and trimethylamine N-oxide), and in the kinetic profile and therapeutic index of several drugs (e.g., metformin and platinum derivatives). As part of the Special Issue Physiology, Biochemistry, and Pharmacology of Transporters for Organic Cations, this article critically presents the physio-pathological, pharmacological, and toxicological roles of OCTs in the tissues in which they are primarily expressed. | International Journal of Molecular Sciences | [
"Inorganic Chemistry",
"Organic Chemistry",
"Physical and Theoretical Chemistry",
"Computer Science Applications",
"Spectroscopy",
"Molecular Biology",
"Catalysis"
] |
Interaction entre un groupement carboxylique et un groupement aromatique, en serie norbornene, etudiee par rmn du carbone 13 et par mesure du pKa. | Tetrahedron Letters | [
"Organic Chemistry",
"Drug Discovery",
"Biochemistry"
] |
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