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7.36k
NCT02075671
,33:55:treatment,46:55:treatment,60:67:chronic_disease,69:82:treatment,84:104:treatment,106:118:treatment,120:132:treatment
History of failing at least one conventional treatment for rosacea (metronidazole, sodium sulfacetamide, tetracycline, azelaic acid) or not interested in continuous treatment with these agents
{ "allergy_name": null, "cancer": null, "chronic_disease": "rosacea", "treatment": "azelaic acid" }
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[ "History", "of", "failing", "at", "least", "one", "conventional", "treatment", "for", "rosacea", "(metronidazole,", "sodium", "sulfacetamide,", "tetracycline,", "azelaic", "acid)", "or", "not", "interested", "in", "continuous", "treatment", "with", "these", "agents" ]
6,797
NCT02346526
10:31:treatment,
Received previous radiotherapy to approximately >25% of bone marrow
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "previous radiotherapy" }
[ 0, 0, 1, 0, 0, 0, 0, 0, 0 ]
[ "Received", "previous", "radiotherapy", "to", "approximately", ">25%", "of", "bone", "marrow" ]
4,563
NCT02977468
,,,176:186:treatment
Female subjects of childbearing potential must be willing to use an adequate method of contraception for the course of the study through 120 days after the last dose of study medication
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "medication" }
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619
NCT01925131
1:22:treatment,
Monoclonal antibodies must not have been received for 1 week prior to registration
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "Monoclonal antibodies" }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ "Monoclonal", "antibodies", "must", "not", "have", "been", "received", "for", "1", "week", "prior", "to", "registration" ]
3,297
NCT02070549
,44:68:chronic_disease,
History or evidence of current >= class II congestive heart failure as defined by the New York Heart Association (NYHA) functional classification system
{ "allergy_name": null, "cancer": null, "chronic_disease": "congestive heart failure", "treatment": null }
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812
NCT02981173
10:26:chronic_disease
Episodic cluster headache with periods that are predictable
{ "allergy_name": null, "cancer": null, "chronic_disease": "cluster headache", "treatment": null }
[ 0, 0, 0, 0, 0, 0, 0, 0 ]
[ "Episodic", "cluster", "headache", "with", "periods", "that", "are", "predictable" ]
3,747
NCT02451215
1:11:cancer
Ependymoma
{ "allergy_name": null, "cancer": "Ependymoma", "chronic_disease": null, "treatment": null }
[ 3 ]
[ "Ependymoma" ]
4,409
NCT01464034
17:35:treatment,37:44:treatment,59:76:treatment,,140:148:treatment,213:236:chronic_disease
Exposure to any prior chemotherapy, steroid use, or other myeloma treatment within 14 days prior to first dose. Pts currently on long term steroids do not require any washout period. in addition, steroid use for spinal cord compression is permitted and does not require a washout period
{ "allergy_name": null, "cancer": null, "chronic_disease": "spinal cord compression", "treatment": "steroids" }
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7,205
NCT02577406
,,,,,389:398:treatment,436:446:treatment,484:495:treatment
Male subjects must agree to practice true abstinence from sexual intercourse or to the use of highly effective contraceptive methods (as described above) with non-pregnant female partners of childbearing potential at screening and throughout the course of the study, and should avoid conception with their partners durin...
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "azacitidine" }
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5,933
NCT01956084
7:10:chronic_disease
Donor HIV negative
{ "allergy_name": null, "cancer": null, "chronic_disease": "HIV", "treatment": null }
[ 0, 2, 0 ]
[ "Donor", "HIV", "negative" ]
186
NCT02204098
,,,125:138:cancer,197:204:treatment,230:235:cancer
Clinical T2-T4c, any N, M0 invasive ER+ (Allred Score of 6-8) and HER2- (0 or 1+ by IHC or FISH negative for amplification) breast cancer by AJCC 7th edition clinical staging, with the goal being surgery to completely excise the tumor in the breast and the lymph node
{ "allergy_name": null, "cancer": "tumor", "chronic_disease": null, "treatment": "surgery" }
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6,626
NCT02563574
1:26:chronic_disease
Major psychiatric illness
{ "allergy_name": null, "cancer": null, "chronic_disease": "Major psychiatric illness", "treatment": null }
[ 0, 2, 2 ]
[ "Major", "psychiatric", "illness" ]
2,525
NCT03042689
14:55:cancer
Diagnosis of relapsed/refractory advanced malignancies
{ "allergy_name": null, "cancer": "relapsed/refractory advanced malignancies", "chronic_disease": null, "treatment": null }
[ 0, 0, 0, 0, 3 ]
[ "Diagnosis", "of", "relapsed/refractory", "advanced", "malignancies" ]
3,668
NCT01976169
10:13:chronic_disease
Baseline HIV screening
{ "allergy_name": null, "cancer": null, "chronic_disease": "HIV", "treatment": null }
[ 0, 2, 0 ]
[ "Baseline", "HIV", "screening" ]
184
NCT02555280
1:22:chronic_disease,,
Mild lumbar scoliosis (Cobb angle up to 25º)
{ "allergy_name": null, "cancer": null, "chronic_disease": "Mild lumbar scoliosis", "treatment": null }
[ 0, 0, 2, 0, 0, 0, 0, 0 ]
[ "Mild", "lumbar", "scoliosis", "(Cobb", "angle", "up", "to", "25º)" ]
4,190
NCT02304458
28:61:treatment
Patients who have received prior solid organ transplantation
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "prior solid organ transplantation" }
[ 0, 0, 0, 0, 0, 0, 0, 1 ]
[ "Patients", "who", "have", "received", "prior", "solid", "organ", "transplantation" ]
2,882
NCT02583893
1:11:treatment,18:25:treatment,43:54:treatment,56:68:treatment,70:82:treatment,84:96:treatment,102:114:treatment,
Tacrolimus (e.g. Prograf) Subjects taking fluconozole, voriconizole, itraconazole, posaconazole, and ketokonazole within 72 hours of study drug starting
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "ketokonazole" }
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5,909
NCT02981069
30:64:chronic_disease,,,,,,,
Individuals with evidence of proliferative diabetic retinopathy, plasma creatinine >1.4 females or >1.5 males, or 24-hour urine albumin excretion > 300 mg will be excluded
{ "allergy_name": null, "cancer": null, "chronic_disease": "proliferative diabetic retinopathy", "treatment": null }
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[ "Individuals", "with", "evidence", "of", "proliferative", "diabetic", "retinopathy,", "plasma", "creatinine", ">1.4", "females", "or", ">1.5", "males,", "or", "24-hour", "urine", "albumin", "excretion", ">", "300", "mg", "will", "be", "excluded" ]
3,080
NCT02473250
1:14:chronic_disease
renal failure
{ "allergy_name": null, "cancer": null, "chronic_disease": "renal failure", "treatment": null }
[ 0, 0 ]
[ "renal", "failure" ]
1,858
NCT03149783
39:50:allergy_name
Patients with a documented allergy to ropivacaine
{ "allergy_name": "ropivacaine", "cancer": null, "chronic_disease": null, "treatment": null }
[ 0, 0, 0, 0, 0, 0, 4 ]
[ "Patients", "with", "a", "documented", "allergy", "to", "ropivacaine" ]
3,527
NCT02554253
15:32:chronic_disease,,
pre-operative renal dysfunction including a baseline creatinine equal to or greater than 1.5 mg/dL or requiring dialysis
{ "allergy_name": null, "cancer": null, "chronic_disease": "renal dysfunction", "treatment": null }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1 ]
[ "pre-operative", "renal", "dysfunction", "including", "a", "baseline", "creatinine", "equal", "to", "or", "greater", "than", "1.5", "mg/dL", "or", "requiring", "dialysis" ]
2,082
NCT00924027
1:12:cancer
Lung cancer
{ "allergy_name": null, "cancer": "Lung cancer", "chronic_disease": null, "treatment": null }
[ 0, 3 ]
[ "Lung", "cancer" ]
2,997
NCT02081404
12:31:chronic_disease
History of Barrett's esophagus
{ "allergy_name": null, "cancer": null, "chronic_disease": "Barrett's esophagus", "treatment": null }
[ 0, 0, 0, 0 ]
[ "History", "of", "Barrett's", "esophagus" ]
2,561
NCT02925923
1:10:treatment
Lopinavir
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "Lopinavir" }
[ 1 ]
[ "Lopinavir" ]
3,806
NCT02105545
29:62:chronic_disease
Patients may have existing, non-oncological genetic disorders
{ "allergy_name": null, "cancer": null, "chronic_disease": "non-oncological genetic disorders", "treatment": null }
[ 0, 0, 0, 0, 0, 0, 0 ]
[ "Patients", "may", "have", "existing,", "non-oncological", "genetic", "disorders" ]
4,865
NCT01760655
1:4:cancer
ALL with any morphological evidence of disease will not be eligible
{ "allergy_name": null, "cancer": "ALL", "chronic_disease": null, "treatment": null }
[ 3, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ "ALL", "with", "any", "morphological", "evidence", "of", "disease", "will", "not", "be", "eligible" ]
2,499
NCT02338232
17:31:treatment,33:54:treatment,59:73:treatment,88:115:treatment,200:219:treatment
Subjects taking ACE inhibitors, potassium supplements, or spironolactone (or any other potassium-sparing diuretics) who cannot discontinue use prior to initiation of study treatment OR who require a high-potassium diet
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "high-potassium diet" }
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6,459
NCT02982226
,38:85:treatment,93:114:treatment,116:121:treatment,123:129:treatment,131:140:treatment,142:158:treatment
Completed a minimum of two months of conservative, non-injection treatment/therapies (i.e., activity modification, icing, NSAIDs, orthotics, physical therapy, etc.)
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "physical therapy" }
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5,686
NCT02207439
,,,61:83:chronic_disease
Weight loss of > 10% over the past 6 months which is due to tumor wasting syndrome
{ "allergy_name": null, "cancer": null, "chronic_disease": "tumor wasting syndrome", "treatment": null }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 0, 2 ]
[ "Weight", "loss", "of", ">", "10%", "over", "the", "past", "6", "months", "which", "is", "due", "to", "tumor", "wasting", "syndrome" ]
4,731
NCT02809677
9:19:chronic_disease
current depression secondary to substances or general medical condition
{ "allergy_name": null, "cancer": null, "chronic_disease": "depression", "treatment": null }
[ 0, 2, 0, 0, 0, 0, 0, 0, 0 ]
[ "current", "depression", "secondary", "to", "substances", "or", "general", "medical", "condition" ]
1,482
NCT01676259
1:18:chronic_disease
hepatitis B virus
{ "allergy_name": null, "cancer": null, "chronic_disease": "hepatitis B virus", "treatment": null }
[ 2, 0, 0 ]
[ "hepatitis", "B", "virus" ]
3,321
NCT02780401
1:16:chronic_disease,
Unstable angina within 4 months prior to enrollment
{ "allergy_name": null, "cancer": null, "chronic_disease": "Unstable angina", "treatment": null }
[ 0, 2, 0, 0, 0, 0, 0, 0 ]
[ "Unstable", "angina", "within", "4", "months", "prior", "to", "enrollment" ]
1,789
NCT01505062
29:39:allergy_name
Contraindications to use of anesthesia (local or general, as appropriate)
{ "allergy_name": "anesthesia", "cancer": null, "chronic_disease": null, "treatment": null }
[ 0, 0, 0, 0, 4, 0, 0, 0, 0, 0 ]
[ "Contraindications", "to", "use", "of", "anesthesia", "(local", "or", "general,", "as", "appropriate)" ]
1,954
NCT02411656
24:58:chronic_disease
Has a known history of human immunodeficiency virus (HIV)
{ "allergy_name": null, "cancer": null, "chronic_disease": "human immunodeficiency virus (HIV)", "treatment": null }
[ 0, 0, 0, 0, 0, 0, 2, 0, 0 ]
[ "Has", "a", "known", "history", "of", "human", "immunodeficiency", "virus", "(HIV)" ]
1,378
NCT02400463
,,,99:108:treatment
all females of child-bearing potential must have a negative serum pregnancy test within 7 days of treatment
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "treatment" }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1 ]
[ "all", "females", "of", "child-bearing", "potential", "must", "have", "a", "negative", "serum", "pregnancy", "test", "within", "7", "days", "of", "treatment" ]
1,058
NCT01799538
1:21:chronic_disease
Cognitive Impairment
{ "allergy_name": null, "cancer": null, "chronic_disease": "Cognitive Impairment", "treatment": null }
[ 0, 0 ]
[ "Cognitive", "Impairment" ]
5,090
NCT02780401
,35:62:treatment,64:76:treatment,78:97:treatment,111:127:treatment
Patients must be at least 28 days post cytotoxic chemotherapy, radiotherapy, monoclonal antibody and/or other biologic therapy, prior to enrollment
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "biologic therapy" }
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5,800
NCT02394028
1:49:treatment,54:56:chronic_disease,86:95:chronic_disease
Treatment with antibiotics as adjunctive therapy for CD in the absence of documented infection
{ "allergy_name": null, "cancer": null, "chronic_disease": "infection", "treatment": "Treatment with antibiotics as adjunctive therapy" }
[ 0, 0, 1, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 2 ]
[ "Treatment", "with", "antibiotics", "as", "adjunctive", "therapy", "for", "CD", "in", "the", "absence", "of", "documented", "infection" ]
6,358
NCT02452697
15:35:chronic_disease,55:88:treatment,92:131:treatment
Patients with hematologic diseases who have undergone T-cell depleted reduced intensity or non-ablative allogeneic transplantation, using a 7-8/8 HLA-matched related or unrelated donor or 4-6/8 HLA-matched related donor
{ "allergy_name": null, "cancer": null, "chronic_disease": "hematologic diseases", "treatment": "non-ablative allogeneic transplantation" }
[ 0, 0, 2, 0, 0, 0, 0, 3, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ "Patients", "with", "hematologic", "diseases", "who", "have", "undergone", "T-cell", "depleted", "reduced", "intensity", "or", "non-ablative", "allogeneic", "transplantation,", "using", "a", "7-8/8", "HLA-matched", "related", "or", "unrelated", "donor", "or", "4-6/8",...
6,250
NCT02133872
,49:65:treatment
More than one in-patient hospitalization for an antihypertensive crisis within the year
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "antihypertensive" }
[ 0, 0, 0, 0, 1, 0, 0, 1, 0, 0, 0, 0 ]
[ "More", "than", "one", "in-patient", "hospitalization", "for", "an", "antihypertensive", "crisis", "within", "the", "year" ]
4,828
NCT02145351
1:16:treatment,21:23:chronic_disease,29:54:treatment,58:72:treatment
Acute treatment for HF with intravenous loop diuretic or hemofiltration
{ "allergy_name": null, "cancer": null, "chronic_disease": "HF", "treatment": "hemofiltration" }
[ 0, 1, 0, 2, 0, 0, 0, 0, 0, 1 ]
[ "Acute", "treatment", "for", "HF", "with", "intravenous", "loop", "diuretic", "or", "hemofiltration" ]
6,704
NCT01045148
7:14:chronic_disease,18:37:chronic_disease,104:113:treatment
Major medical or psychiatric illness, which in the investigator's opinion, would prevent completion of treatment and would interfere with follow-up
{ "allergy_name": null, "cancer": null, "chronic_disease": "psychiatric illness", "treatment": "treatment" }
[ 0, 0, 0, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0 ]
[ "Major", "medical", "or", "psychiatric", "illness,", "which", "in", "the", "investigator's", "opinion,", "would", "prevent", "completion", "of", "treatment", "and", "would", "interfere", "with", "follow-up" ]
5,399
NCT02311621
1:20:cancer
Skull based disease with soft tissue extension
{ "allergy_name": null, "cancer": "Skull based disease", "chronic_disease": null, "treatment": null }
[ 0, 0, 0, 0, 0, 0, 0 ]
[ "Skull", "based", "disease", "with", "soft", "tissue", "extension" ]
4,622
NCT02466750
,87:94:treatment
Agree to defer blood, bone marrow, and organ donation for 1 year after receipt of the vaccine
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "vaccine" }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 4 ]
[ "Agree", "to", "defer", "blood,", "bone", "marrow,", "and", "organ", "donation", "for", "1", "year", "after", "receipt", "of", "the", "vaccine" ]
2,011
NCT02624258
14:30:chronic_disease
Uncontrolled active infection
{ "allergy_name": null, "cancer": null, "chronic_disease": "active infection", "treatment": null }
[ 0, 0, 2 ]
[ "Uncontrolled", "active", "infection" ]
265
NCT02833207
1:47:treatment
non-steroidal anti-inflammatory drugs (NSAIDs)
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "non-steroidal anti-inflammatory drugs (NSAIDs)" }
[ 0, 1, 0, 0 ]
[ "non-steroidal", "anti-inflammatory", "drugs", "(NSAIDs)" ]
3,059
NCT02535312
1:25:treatment
anti-seizure medications are eligible to participate
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "anti-seizure medications" }
[ 0, 1, 0, 0, 0, 0 ]
[ "anti-seizure", "medications", "are", "eligible", "to", "participate" ]
4,230
NCT02709980
1:26:chronic_disease
major depressive disorder
{ "allergy_name": null, "cancer": null, "chronic_disease": "major depressive disorder", "treatment": null }
[ 0, 0, 2 ]
[ "major", "depressive", "disorder" ]
2,111
NCT02445768
1:12:chronic_disease,16:32:chronic_disease,48:51:treatment
subcortical or cortical infarct confirmed with MRI
{ "allergy_name": null, "cancer": null, "chronic_disease": "cortical infarct", "treatment": "MRI" }
[ 0, 0, 0, 0, 0, 0, 4 ]
[ "subcortical", "or", "cortical", "infarct", "confirmed", "with", "MRI" ]
6,273
NCT01220583
,,,123:132:treatment,
Women of childbearing potential and male participants who are sexually active must practice adequate contraception during treatment and for 6 weeks following treatment
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "treatment" }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 1 ]
[ "Women", "of", "childbearing", "potential", "and", "male", "participants", "who", "are", "sexually", "active", "must", "practice", "adequate", "contraception", "during", "treatment", "and", "for", "6", "weeks", "following", "treatment" ]
1,236
NCT02624258
69:88:allergy_name,90:94:allergy_name,100:110:allergy_name
History of allergy or hypersensitivity to study product excipients (human serum albumin, DMSO, and Dextran 40)
{ "allergy_name": "Dextran 40", "cancer": null, "chronic_disease": null, "treatment": null }
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[ "History", "of", "allergy", "or", "hypersensitivity", "to", "study", "product", "excipients", "(human", "serum", "albumin,", "DMSO,", "and", "Dextran", "40)" ]
5,865
NCT02135588
,22:41:treatment
At least 7 days from prior major surgery
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "prior major surgery" }
[ 0, 0, 0, 0, 0, 0, 0, 1 ]
[ "At", "least", "7", "days", "from", "prior", "major", "surgery" ]
3,313
NCT02579967
15:49:chronic_disease,53:83:chronic_disease,109:117:cancer,165:189:chronic_disease
Patients with hemophagocytic lymphohistiocytosis or macrophage activation syndrome related to an underlying lymphoma with no other clinical history suggestive of a primary immunodeficiency
{ "allergy_name": null, "cancer": "lymphoma", "chronic_disease": "primary immunodeficiency", "treatment": null }
[ 0, 0, 0, 0, 0, 0, 0, 2, 0, 0, 0, 0, 3, 0, 0, 0, 0, 0, 0, 0, 0, 0, 2 ]
[ "Patients", "with", "hemophagocytic", "lymphohistiocytosis", "or", "macrophage", "activation", "syndrome", "related", "to", "an", "underlying", "lymphoma", "with", "no", "other", "clinical", "history", "suggestive", "of", "a", "primary", "immunodeficiency" ]
5,926
NCT01908777
24:34:treatment
progressive disease at transplant work-up
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "transplant" }
[ 0, 0, 0, 1, 0 ]
[ "progressive", "disease", "at", "transplant", "work-up" ]
1,594
NCT00862433
7:19:chronic_disease
Known coagulopathy
{ "allergy_name": null, "cancer": null, "chronic_disease": "coagulopathy", "treatment": null }
[ 0, 2 ]
[ "Known", "coagulopathy" ]
1,642
NCT02392572
51:64:treatment,
Persistent clinically significant toxicities from prior therapy must not be greater than grade 1
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "prior therapy" }
[ 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0 ]
[ "Persistent", "clinically", "significant", "toxicities", "from", "prior", "therapy", "must", "not", "be", "greater", "than", "grade", "1" ]
19
NCT02382419
,14:21:treatment,,111:126:treatment,111:114:chronic_disease,115:126:treatment,,342:352:treatment,,,478:486:treatment,,
Women in the vaccine-eligible age range cannot have received vaccine prior to enrollment, but will be offered HPV vaccination at the end of the study; in brief, we are interested in the efficacy of intervention in preventing HPV in the absence of HPV vaccination, since most women worldwide who might utilize interventio...
{ "allergy_name": null, "cancer": null, "chronic_disease": "HPV", "treatment": "Vaccines" }
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6,391
NCT01684904
15:44:cancer
Patients with cervical esophageal carcinoma
{ "allergy_name": null, "cancer": "cervical esophageal carcinoma", "chronic_disease": null, "treatment": null }
[ 0, 0, 0, 3, 3 ]
[ "Patients", "with", "cervical", "esophageal", "carcinoma" ]
3,155
NCT02408861
1:4:chronic_disease,,
HIV viral load should be well suppressed, defined as below the limit of detection of the local assay or below 75 copies/mL by Food and Drug Administration (FDA)-approved assays, within 4 weeks prior to registration
{ "allergy_name": null, "cancer": null, "chronic_disease": "HIV", "treatment": null }
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124
NCT01436968
1:14:chronic_disease,32:41:chronic_disease,52:61:chronic_disease
Liver disease, including known cirrhosis or active hepatitis
{ "allergy_name": null, "cancer": null, "chronic_disease": "hepatitis", "treatment": null }
[ 0, 0, 0, 0, 2, 0, 0, 2 ]
[ "Liver", "disease,", "including", "known", "cirrhosis", "or", "active", "hepatitis" ]
7,210
NCT02181478
1:19:treatment,24:47:cancer,51:88:cancer
Concurrent therapy for extramedullary leukemia or central nervous system (CNS) lymphoma
{ "allergy_name": null, "cancer": "central nervous system (CNS) lymphoma", "chronic_disease": null, "treatment": "Concurrent therapy" }
[ 0, 1, 0, 0, 3, 0, 0, 0, 0, 0, 3 ]
[ "Concurrent", "therapy", "for", "extramedullary", "leukemia", "or", "central", "nervous", "system", "(CNS)", "lymphoma" ]
6,658
NCT02495168
18:43:treatment,
plans to receive investigational treatment within 30 days after the study is completed
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "investigational treatment" }
[ 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ "plans", "to", "receive", "investigational", "treatment", "within", "30", "days", "after", "the", "study", "is", "completed" ]
3,271
NCT02593123
1:35:cancer
Chronic myelogenous leukemia (CML)
{ "allergy_name": null, "cancer": "Chronic myelogenous leukemia (CML)", "chronic_disease": null, "treatment": null }
[ 0, 0, 3, 0 ]
[ "Chronic", "myelogenous", "leukemia", "(CML)" ]
2,859
NCT02053909
,,53:74:treatment
Serum creatinine >1.8 mg/dL (need for contrast with CT coronary angiogram)
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "CT coronary angiogram" }
[ 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0 ]
[ "Serum", "creatinine", ">1.8", "mg/dL", "(need", "for", "contrast", "with", "CT", "coronary", "angiogram)" ]
4,918
NCT01754298
1:13:treatment
chemotherapy treatment
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "chemotherapy" }
[ 1, 1 ]
[ "chemotherapy", "treatment" ]
370
NCT02664909
12:30:chronic_disease
history of pulmonary embolism
{ "allergy_name": null, "cancer": null, "chronic_disease": "pulmonary embolism", "treatment": null }
[ 0, 0, 2, 0 ]
[ "history", "of", "pulmonary", "embolism" ]
2,342
NCT02962557
27:50:treatment,52:65:treatment,67:84:treatment,90:103:treatment
Sample procedures include major extremity surgery, spine surgery, abdominal surgery, and chest surgery that require a post operative in patient hospital stay
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "chest surgery" }
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5,696
NCT02393794
1:14:cancer,30:47:chronic_disease,64:80:treatment
Breast cancer that is either stage III disease not amenable to curative therapy or stage IV
{ "allergy_name": null, "cancer": "Breast cancer", "chronic_disease": "stage III disease", "treatment": "curative therapy" }
[ 0, 3, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0 ]
[ "Breast", "cancer", "that", "is", "either", "stage", "III", "disease", "not", "amenable", "to", "curative", "therapy", "or", "stage", "IV" ]
6,361
NCT02553941
1:11:cancer,25:40:treatment,,122:132:treatment
Malignancy treated with curative intent and with no known active disease present for >= 1 years before the first dose of study drug and felt to be at low risk for recurrence by treating physician
{ "allergy_name": null, "cancer": "Malignancy", "chronic_disease": null, "treatment": "study drug" }
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5,998
NCT02488057
1:9:chronic_disease
diabetic
{ "allergy_name": null, "cancer": null, "chronic_disease": "diabetic", "treatment": null }
[ 2 ]
[ "diabetic" ]
2,222
NCT02555189
19:36:treatment,38:50:treatment,52:63:treatment
Administration of antifungal agents (itraconazole, fluconazole, etc) within 4 weeks of enrollment or unrecovered AEs due to agents administered more than 4 weeks of enrollment
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "fluconazole" }
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[ "Administration", "of", "antifungal", "agents", "(itraconazole,", "fluconazole,", "etc)", "within", "4", "weeks", "of", "enrollment", "or", "unrecovered", "AEs", "due", "to", "agents", "administered", "more", "than", "4", "weeks", "of", "enrollment" ]
5,989
NCT03158519
19:34:treatment,66:75:treatment,79:98:treatment,111:118:treatment,120:129:treatment,138:150:treatment,
Completion of all primary therapy (with the exception of ongoing endocrine or trastuzumab therapy), including surgery, radiation, and/or chemotherapy greater than 4 weeks prior to study enrollment
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "chemotherapy" }
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5,523
NCT01660607
1:4:chronic_disease
HIV ab
{ "allergy_name": null, "cancer": null, "chronic_disease": "HIV", "treatment": null }
[ 2, 0 ]
[ "HIV", "ab" ]
201
NCT03005951
1:20:chronic_disease
Developmental delay
{ "allergy_name": null, "cancer": null, "chronic_disease": "Developmental delay", "treatment": null }
[ 0, 0 ]
[ "Developmental", "delay" ]
3,723
NCT01572480
,59:62:cancer,,,
Progressive increase in M protein level (evolving type of SMM; increase in serum M protein by greater than or equal to 25% on 2 successive evaluations within a 6-month period)
{ "allergy_name": null, "cancer": "SMM", "chronic_disease": null, "treatment": null }
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2,965
NCT01312857
18:28:cancer
History of other malignancy
{ "allergy_name": null, "cancer": "malignancy", "chronic_disease": null, "treatment": null }
[ 0, 0, 0, 2 ]
[ "History", "of", "other", "malignancy" ]
555
NCT01895777
24:43:chronic_disease
including known active hepatitis A, B or C
{ "allergy_name": null, "cancer": null, "chronic_disease": "hepatitis A, B or C", "treatment": null }
[ 0, 0, 0, 2, 0, 0, 0, 2 ]
[ "including", "known", "active", "hepatitis", "A,", "B", "or", "C" ]
3,347
NCT02851914
12:30:chronic_disease
History of psychotic disorder
{ "allergy_name": null, "cancer": null, "chronic_disease": "psychotic disorder", "treatment": null }
[ 0, 0, 2, 2 ]
[ "History", "of", "psychotic", "disorder" ]
1,668
NCT03186872
35:44:chronic_disease
evidence of active suicidality or psychosis (brief screen conducted by SWer in clinic using DSM-V cross cutting symptom inventory) to assess for psychosis
{ "allergy_name": null, "cancer": null, "chronic_disease": "psychosis", "treatment": null }
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[ "evidence", "of", "active", "suicidality", "or", "psychosis", "(brief", "screen", "conducted", "by", "SWer", "in", "clinic", "using", "DSM-V", "cross", "cutting", "symptom", "inventory)", "to", "assess", "for", "psychosis" ]
1,603
NCT03116464
44:52:chronic_disease,
Be involved in the care of the person with dementia (at least 4 hours of care per day)
{ "allergy_name": null, "cancer": null, "chronic_disease": "dementia", "treatment": null }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 2, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ "Be", "involved", "in", "the", "care", "of", "the", "person", "with", "dementia", "(at", "least", "4", "hours", "of", "care", "per", "day)" ]
1,315
NCT02805504
12:23:allergy_name
Allergy to bupivacaine
{ "allergy_name": "bupivacaine", "cancer": null, "chronic_disease": null, "treatment": null }
[ 0, 0, 4 ]
[ "Allergy", "to", "bupivacaine" ]
3,924
NCT02566304
28:39:treatment,43:65:treatment,,88:98:treatment,131:140:treatment
Patients who have received alemtuzumab or antithymocyte globulin within 8 weeks of the transplant admission. The absence of these therapies in the medical record will serve as documentation that they were not given
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "therapies" }
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[ "Patients", "who", "have", "received", "alemtuzumab", "or", "antithymocyte", "globulin", "within", "8", "weeks", "of", "the", "transplant", "admission.", "The", "absence", "of", "these", "therapies", "in", "the", "medical", "record", "will", "serve", "as", "docu...
5,961
NCT02549833
34:51:chronic_disease
History or clinical suspicion of neurofibromatosis
{ "allergy_name": null, "cancer": null, "chronic_disease": "neurofibromatosis", "treatment": null }
[ 0, 0, 0, 0, 0, 2 ]
[ "History", "or", "clinical", "suspicion", "of", "neurofibromatosis" ]
4,206
NCT02531932
,,63:72:treatment
Negative serum pregnancy test within 7 days prior to starting treatment
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "treatment" }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1 ]
[ "Negative", "serum", "pregnancy", "test", "within", "7", "days", "prior", "to", "starting", "treatment" ]
988
NCT00862433
1:7:chronic_disease
Anemia
{ "allergy_name": null, "cancer": null, "chronic_disease": "Anemia", "treatment": null }
[ 2 ]
[ "Anemia" ]
245
NCT02561988
1:7:cancer
SM-AHN
{ "allergy_name": null, "cancer": "SM-AHN", "chronic_disease": null, "treatment": null }
[ 3 ]
[ "SM-AHN" ]
4,182
NCT01737502
1:18:cancer
carcinoma-in-situ of the cervix
{ "allergy_name": null, "cancer": "carcinoma-in-situ", "chronic_disease": null, "treatment": null }
[ 3, 0, 0, 2 ]
[ "carcinoma-in-situ", "of", "the", "cervix" ]
3,411
NCT02242110
1:24:chronic_disease
Intellectual disability
{ "allergy_name": null, "cancer": null, "chronic_disease": "Intellectual disability", "treatment": null }
[ 0, 0 ]
[ "Intellectual", "disability" ]
3,215
NCT02541565
,,,149:159:treatment
Female subject of childbearing potential should have a negative urine or serum pregnancy within 72 hours prior to receiving the first dose of study medication
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "medication" }
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[ "Female", "subject", "of", "childbearing", "potential", "should", "have", "a", "negative", "urine", "or", "serum", "pregnancy", "within", "72", "hours", "prior", "to", "receiving", "the", "first", "dose", "of", "study", "medication" ]
621
NCT02502708
34:46:treatment,48:64:treatment,73:82:treatment
Patients previously treated with temozolomide, cyclophosphamide, and/or etoposide are eligible for enrollment
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "etoposide" }
[ 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0 ]
[ "Patients", "previously", "treated", "with", "temozolomide,", "cyclophosphamide,", "and/or", "etoposide", "are", "eligible", "for", "enrollment" ]
6,142
NCT01970176
1:13:chronic_disease,17:48:chronic_disease,50:57:chronic_disease,59:66:chronic_disease
Infiltrative or inflammatory myocardial disease (amyloid, sarcoid)
{ "allergy_name": null, "cancer": null, "chronic_disease": "sarcoid", "treatment": null }
[ 0, 0, 0, 0, 0, 0, 0 ]
[ "Infiltrative", "or", "inflammatory", "myocardial", "disease", "(amyloid,", "sarcoid)" ]
6,925
NCT01306045
15:43:cancer,27:43:cancer,110:119:chronic_disease,163:173:chronic_disease,163:185:chronic_disease,292:301:treatment,339:363:cancer,,428:443:treatment,
Patients with symptomatic brain metastases should be excluded from this clinical trial because of their poor prognosis and because they often develop progressive neurologic dysfunction that would confound the evaluation of neurologic and other adverse events. However, patients who have had treatment for their brain met...
{ "allergy_name": null, "cancer": "brain metastatic disease", "chronic_disease": "neurologic dysfunction", "treatment": "brain radiation" }
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7,248
NCT01754298
1:13:treatment
chemotherapy treatment
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "chemotherapy" }
[ 1, 1 ]
[ "chemotherapy", "treatment" ]
732
NCT02188745
7:18:chronic_disease,
Known CNS disease, unless clinically stable for ≥ 3 months
{ "allergy_name": null, "cancer": null, "chronic_disease": "CNS disease", "treatment": null }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ "Known", "CNS", "disease,", "unless", "clinically", "stable", "for", "≥", "3", "months" ]
1,942
NCT02955394
1:38:treatment,40:51:treatment,53:60:treatment,62:74:treatment,76:88:treatment,90:97:treatment,99:106:treatment,108:115:treatment,117:124:treatment,126:132:treatment
Prior treatment with an anti-androgen (abiraterone, ARN-509, bicalutamide, enzalutamide, ODM-201, TAK-448, TAK-683, TAK-700, VT-464)
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "VT-464" }
[ 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ "Prior", "treatment", "with", "an", "anti-androgen", "(abiraterone,", "ARN-509,", "bicalutamide,", "enzalutamide,", "ODM-201,", "TAK-448,", "TAK-683,", "TAK-700,", "VT-464)" ]
5,440
NCT02370693
,,,,58:71:treatment
Fall in FVC > 10% over 6 months on at least 12 months of prior therapy
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "prior therapy" }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1 ]
[ "Fall", "in", "FVC", ">", "10%", "over", "6", "months", "on", "at", "least", "12", "months", "of", "prior", "therapy" ]
21
NCT02334579
23:46:cancer
Histologically proven prostate adenocarcinoma
{ "allergy_name": null, "cancer": "prostate adenocarcinoma", "chronic_disease": null, "treatment": null }
[ 0, 0, 0, 3 ]
[ "Histologically", "proven", "prostate", "adenocarcinoma" ]
2,103
NCT02815670
36:43:treatment,47:65:treatment,81:92:treatment
A condition requiring an emergency surgery or invasive procedure where adequate haemostasis
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "haemostasis" }
[ 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 1 ]
[ "A", "condition", "requiring", "an", "emergency", "surgery", "or", "invasive", "procedure", "where", "adequate", "haemostasis" ]
5,788
NCT02660528
21:59:treatment
having received the Bacillus Calmette-Guérin (BCG) vaccine
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "Bacillus Calmette-Guérin (BCG) vaccine" }
[ 0, 0, 0, 0, 0, 0, 4 ]
[ "having", "received", "the", "Bacillus", "Calmette-Guérin", "(BCG)", "vaccine" ]
4,038
NCT02073097
16:27:treatment,99:122:treatment,,,,,,,339:348:treatment,,,,,,,699:710:treatment
The effects of Carfilzomib on the developing human fetus are unknown. For this reason and because chemotherapeutic agents used in this study are known to be teratogenic, women of child-bearing potential and men must agree to use adequate contraception (double barrier method of birth control or abstinence) 2 weeks prior...
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "carfilzomib" }
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