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10,010,103
Slow changes and Wiener analysis of nonlinear summation in contractions in cat muscles.
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10,010,104
With regular trains of stimuli at a high frequency, the contribution of each stimulus to the force generated over time declines from the second to about the tenth stimulus, but then begins to increase again. This late increase is referred to as tetanic potentiation in analogy with the post-tetanic potentiation of the t...
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10,010,105
The interpretation of biological motion.
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10,010,106
The term biological motion has been coined by Johansson (1973) to refer to the ambulatory patterns of terrestrial bipeds and quadripeds. In this paper a computational theory of the visual perception of biological motion is proposed. The specific problem addressed is how the three-dimensional structure and motions of an...
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10,010,107
Afferent and efferent components of joint position sense; interpretation of kinaesthetic illusion.
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10,010,108
The present model of joint angle perception is based on the following hypotheses: the perception and control of joint angle are closely interrelated processes; central motor commands are adequately expressed by shifts of an equilibrium point resulting from the interaction of antagonistic muscles and a load; two fundame...
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10,010,109
Visual localization during eye tracking on steady background and during steady fixation on moving background.
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10,010,110
Experiments were performed to clarify the role of the background motion on the retina in the phenomenon of mislocation of brief visual stimuli during smooth eye tracking. It was found that these visual stimuli were mislocated also relative to a moving background during steady eye fixation. The magnitude of mislocation ...
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10,010,111
Neural models of brightness perception and retinal rivalry in binocular vision.
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10,010,112
In binocular fusion, pairs of left and right stimuli yielding the same brightness perception constitute an equibrightness curve in a coordinate system whose ordinate and abscissa correspond to left and right stimulus strengths. A neural network model is presented to elucidate the characteristics of the curve. According...
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10,010,113
Volume elasticity of the ocular avascular compartment in vivo and post mortem.
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10,010,114
By considering the frequency dependence of the ocular volume elasticity it is possible to locate the static volume elasticity function of the avascular compartment of the eye in vivo. The procedure used involved measuring the dynamic volume elasticity function E = f(P,v), where E = volume elasticity, P = intraocular pr...
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10,010,115
Spatio-temporal organization of receptive fields of the cat striate cortex. The receptive fields as the grating filters.
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10,010,116
Storage of temporal pattern sequence in a network.
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10,010,117
Learning of single patterns and a temporal pattern sequence in a network when the coupling coefficients between the network elements change their values according to a definite coupling function is described. In contrast to technical systems (e.g. film, tape) where temporal sequences are often encoded in the storage lo...
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10,010,118
On the character of an distance between states in a binary switching net.
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10,010,119
Behavioral examination of binary switching net models has typically concerned itself with an examination of their cyclical character. This article considers two less frequently discussed behavioral variables--the density of "1"s in net states and the (Hamming) distance between net states. These variables are studied un...
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10,010,120
Multiplication noise in the human visual system at threshold: 2. Probit estimation of parameters.
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10,010,121
A mathematical technique is described that relates detection model parameters to stimulus magnitude and experimental probability of detection. The normalizing transform is used to make the response statistics approximately Gaussian. Conventional probit analysis is then applied. From measurements at M stimulus levels, a...
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10,010,122
A model for the economical encoding of the visual image in cerebral cortex.
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10,010,123
We propose a model for the first stage of the cortical transformation of the visual image based on the principle that the cortex encodes the information with the minimum number of channels mathematically needed. We restrict our model to be consistent with the data on size adaptations, the known relationships of acuity ...
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10,010,124
[Polyacrylamide gel electrophoretic study of cattle pancreatic proteins].
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10,010,125
Dexamethasone suppression test: problems and promise.
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10,010,126
Plasma copper and dopamine-beta-hydroxylase in schizophrenia.
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10,010,127
Platelet serotonin uptake in depressed patients: circadian effect.
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10,010,128
Postprandial hypoglycemia and "psychological"symptoms.
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10,010,129
Excessive mirror movements and aggression.
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10,010,130
The presence of mirror movements was assessed as part of the overall neurological examination of 170 inpatients in a child psychiatric unit. It was found that when patients were divided by presence or absence of problems of repetitive aggressiveness, the aggressive patients, particularly the subgroup of aggressive male...
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10,010,131
The dexamethasone suppression test and familial subtypes of depression--a naturalistic replication.
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10,010,132
The authors used a naturalistic design to replicate studies which validated the familial subtyping of primary depression. Ninety-three inpatients with unipolar depression had received the DST within 1 week of admission and were free of confounding medical problems. A blind rater assigned diagnoses based on chart materi...
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10,010,133
Dexamethasone suppression test in primary depression: significance of family history and psychosis.
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10,010,134
The overnight dexamethasone suppression test (DST) was administered to 31 inpatients with endogenous depression. DST results were abnormal in 42% of the group and in 67% of those patients with psychotic depression. Division of the sample into genetic subtypes based on family history criteria of Winokur et al. failed to...
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10,010,135
Quantitative investigation on the urinary excretion and metabolism of 3,4-dimethoxyphenylethylamine in schizophrenics and normal individuals.
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10,010,136
A quantitative method for the detection of DMPEA in urine was developed. It is based on the fluorometric determination of DMPEA in the form of its phosphopyridoxyl derivate. The limit of detection is 2 microgram DMPEA per 1 g creatinine. The DMPEA content was measured in urine from healthy persons, from schizophrenics,...
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10,010,137
Changes in neuropsychological test performance after electroconvulsive therapy.
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10,010,138
A group of 231 psychiatric patients were evaluated (with the Wechsler Adult Intelligence Scale and the Halstead-Reitan Neuropsychological Test Battery) before and after electroconvulsive therapy. Improvement during the course of therapy was shown in 96% of the measures and significant improvement (p less than 0.05) occ...
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10,010,139
Dermatoglyphic studies in affective disorders: an appraisal.
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10,010,140
The etiology, nosology, and mode of transmission of affective disorders is still obscure. A number of studies have suggested the division of manic-depressive psychosis into unipolar and bipolar categories with distinct mechanisms of transmission. This study focuses on the role of dermatoglyphics in the study of affecti...
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10,010,141
A new method for the use of salivary lithium concentrations as an indicator of plasma lithium levels.
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10,010,142
[A special muscle-bath with membraneoxygenation for a papillary-muscle assay (author's transl)].
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10,010,143
Photoacoustic photocalorimetry and spectroscopy of Halobacterium halobium purple membranes.
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10,010,144
Enthalpy changes associated with intermediates of the photocycle of bacteriorhodopsin (bR) in light-adapted Halobacterium halobium purple membranes, and decay times of these intermediates, are obtained from photoacoustic measurements on purple membrane fragments. Our results, mainly derived from modulation frequency sp...
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10,010,145
[Stress- and strain analyses of the titanium-net-cement-construction of total hip joint prosthesis by using a simplified finite-element-model (author's transl)].
[ -0.027063503861427307, 0.01724846102297306, 0.01214955560863018, -0.06409009546041489, -0.05876116454601288, -0.015016318298876286, 0.03623507544398308, 0.05788072198629379, 0.0023498868104070425, 0.07176828384399414, -0.10699356347322464, 0.052291449159383774, 0.10262449830770493, 0.03048...
10,010,146
[Computer-aided quality assurance of ultrasonic transducers for use in medical diagnostics (author's transl)].
[ -0.009138396009802818, -0.08104167878627777, 0.03262307122349739, 0.012542053125798702, -0.09714607149362564, -0.059668250381946564, -0.013522585853934288, 0.07444880157709122, -0.05762483924627304, -0.022752011194825172, 0.0029454855248332024, -0.056575994938611984, 0.0514899305999279, 0....
10,010,147
On the wobbling-in-cone analysis of fluorescence anisotropy decay.
[ -0.025603828951716423, -0.07874418050050735, 0.040348898619413376, -0.008377017453312874, 0.0009705534321255982, -0.12465719133615494, -0.01241274457424879, 0.05247088894248009, 0.05642532929778099, 0.04025457426905632, 0.025539247319102287, 0.035414014011621475, -0.05948387086391449, 0.02...
10,010,148
Interpretation of fluorescence anisotropy decay for the case of restricted rotational diffusion often requires a model. To investigate the extent of model dependence, two models are compared: a strict cone model, in which a fluorescent probe wobbles uniformly within a cone, and a Gaussian model, where the stationary di...
[ 0.017825422808527946, -0.11694159358739853, 0.055409058928489685, 0.019131828099489212, 0.019490182399749756, -0.08593101799488068, -0.04076916351914406, 0.03018849901854992, 0.10345059633255005, 0.05487972870469093, 0.05272059142589569, 0.08095831423997879, -0.004154385533183813, 0.056506...
10,010,149
Biochemical profiles of membranes from x-ray and neutron diffraction.
[ -0.0931280106306076, -0.12866300344467163, -0.055765748023986816, -0.025143494829535484, -0.01807445101439953, 0.006505275145173073, 0.08480295538902283, 0.07367280125617981, -0.018975889310240746, -0.07378219068050385, 0.02005889266729355, -0.016824210062623024, -0.014699510298669338, 0.0...
10,010,150
X-ray and neutron diffraction methods provide some information about the distribution of mass in biological membranes and lipid-water systems. Scattering density profiles obtained from these systems, however, usually are not directly interpretable in terms of the relative amounts of chemical constituents (e.g., lipid, ...
[ -0.012350369244813919, -0.17475751042366028, 0.0279122032225132, -0.00705691846087575, -0.021831711754202843, -0.037829723209142685, 0.053071122616529465, 0.08724477887153625, -0.013859922997653484, -0.06339305639266968, 0.029605679214000702, -0.04378826171159744, -0.008643874898552895, 0....
10,010,151
[The biological and biomechanical properties of metal implants coated with bioglass ceramic, as exemplified in the simple model of a loaded cement-free total hip prosthesis (author's transl)].
[ -0.01386333629488945, 0.057461824268102646, 0.027338402345776558, -0.04427644610404968, -0.0966034084558487, -0.01784447208046913, 0.04246726259589195, 0.0719321146607399, -0.03162632882595062, -0.00014087492309045047, -0.11608164757490158, -0.01659971848130226, 0.0243274737149477, 0.04564...
10,010,152
Muscle diffraction theory. Relationship between diffraction subpeaks and discrete sarcomere length distributions.
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10,010,153
A theoretical discussion is presented that describes the diffraction on monochromatic light by a three-dimensional sarcomere array having the following properties. The basic repetitive diffracting unit is the sarcomere. The contiguous arrangement of physically attached serial sarcomeres in the myofibril is contained wi...
[ -0.02753739431500435, -0.04542115703225136, 0.044151220470666885, -0.0969684049487114, -0.028756333515048027, -0.06521930545568466, 0.06310753524303436, 0.027710678055882454, 0.052935779094696045, 0.026565104722976685, -0.0406506210565567, 0.026869243010878563, 0.06323609501123428, 0.01144...
10,010,154
[A method for the polarographic measurement of oxygen solubility coefficients in hydrous solutions of electrolytes (author's transl)].
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10,010,155
Kinetics of rouleau formation. I. A mass action approach with geometric features.
[ 0.0268813818693161, -0.02748945541679859, -0.03347425535321236, 0.03894548490643501, 0.023332813754677773, -0.007275551091879606, -0.058340080082416534, 0.015973474830389023, -0.00929134152829647, 0.008293702267110348, 0.013242527842521667, -0.01800466515123844, -0.014195557683706284, -0.0...
10,010,156
In the presence of certain macromolecules, such as fibrinogen, immunoglobulin, dextran, and polylysine, erythrocytes tend to aggregate and form cylindrical clusters called "rouleaux" in which cells resemble coins in a stack. The aggregates may remain cylindrical or they may branch, forming tree, and networklike structu...
[ -0.012008575722575188, -0.07852775603532791, -0.026786457747220993, 0.040798574686050415, -0.003070160746574402, -0.041847530752420425, 0.008791042491793633, 0.14053814113140106, 0.100649394094944, 0.03130095452070236, -0.04536965861916542, 0.03335145488381386, 0.0011757276952266693, 0.078...
10,010,157
The equilibrium size distribution of rouleaux.
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10,010,158
Rouleaux are formed by the aggregation of red blood cells in the presence of macromolecules that bridge the membranes of adherent erythrocytes. We compute the size and degree of branching of rouleaux for macroscopic systems in thermal equilibrium in the absence of fluid flow. Using techniques from statistical mechanics...
[ 0.032800156623125076, -0.07119090110063553, -0.06026843935251236, 0.04956000670790672, -0.03685422241687775, -0.020532038062810898, 0.032660871744155884, 0.0918610468506813, 0.08376623690128326, -0.04882592335343361, -0.05870048701763153, 0.007339815143495798, 0.0360897034406662, 0.0034274...
10,010,159
1H-NMR relaxation investigation of water bound to bovine rod outer segment disk membranes.
[ -0.05250231921672821, -0.1201620101928711, -0.00935292150825262, -0.014606245793402195, -0.030485544353723526, -0.13350331783294678, 0.062482886016368866, 0.04539039731025696, 0.05505084991455078, -0.04440810903906822, 0.0016398398438468575, 0.0006992309354245663, -0.0432148203253746, 0.06...
10,010,160
Spin-lattice relaxation times T(1) in deuterated aqueous dispersions of lecithin and rod outer segment disk membranes were measured at various concentrations and temperatures. Fast chemical exchange between two loosely defined phases of water molecules was shown to fit the data, allowing the dynamic features of "bound"...
[ -0.01599154993891716, -0.12721315026283264, 0.011072802357375622, -0.044125016778707504, -0.04029955714941025, -0.05295354872941971, 0.06333746761083603, 0.049088411033153534, 0.04603177681565285, -0.025251885876059532, -0.010938025079667568, -0.03579195961356163, 0.02402995526790619, 0.01...
10,010,161
Poly(dA-dT) complexes with histone H1 and pancreatic ribonuclease: specific base recognition evidenced by ultraviolet resonance raman spectroscopy.
[ -0.028416672721505165, -0.05343911424279213, -0.05238976329565048, -0.03479519113898277, -0.017780674621462822, 0.035541169345378876, 0.028743572533130646, -0.02664226107299328, 0.006107799708843231, -0.06430090963840485, -0.06005454808473587, 0.056561361998319626, -0.02816181257367134, 0....
10,010,162
Comparative microcalorimetric dilatometric analysis of the interactions of quinacrine, chloroquine, and ethidium bromide with DNA.
[ -0.018037933856248856, -0.08166954666376114, -0.012013247236609459, -0.0885767787694931, 0.044516630470752716, -0.015598364174365997, -0.02371925674378872, 0.1454424113035202, -0.019113531336188316, 0.06524931639432907, 0.09500721842050552, -0.11209064722061157, 0.006911690346896648, 0.014...
10,010,163
Chromatin structure studied by linear dichroism at different salt concentrations.
[ -0.09915308654308319, -0.03248528018593788, -0.001593009103089571, -0.07819335162639618, -0.0681677982211113, -0.007784664630889893, 0.022047700360417366, 0.012425495311617851, 0.005674509331583977, -0.012407875619828701, 0.0485137440264225, 0.019571609795093536, 0.018664320930838585, 0.02...
10,010,164
The identification of (E)-2-methylglutaconic acid, a new isoleucine metabolite, in the urine of patients with beta-ketothiolase deficiency, propionic acidaemia and methylmalonic acidaemia.
[ -0.0038672967348247766, 0.002992528025060892, -0.050198350101709366, 0.0014625489711761475, -0.019374381750822067, 0.04589248076081276, 0.0056160977110266685, 0.10813069343566895, 0.007178603671491146, -0.027903815731406212, 0.01701705902814865, -0.06620040535926819, -0.03345964848995209, ...
10,010,165
The identification of (E)-2-methylglutaconic acid, a 'new' metabolite of isoleucine, is described. The substance was detected in urine samples from patients with propionic acidaemia, methylmalonic acidaemia and so-called beta-ketothiolase deficiency; in the majority of cases together with N-tiglylglycine. (E)-2-Methylg...
[ -0.03615211322903633, -0.0748593881726265, -0.07031049579381943, -0.016698680818080902, -0.03422700613737106, 0.04979267343878746, -0.04774253070354462, 0.06840866804122925, 0.05589677393436432, -0.034964196383953094, 0.03174953535199165, -0.045349929481744766, -0.055716678500175476, -0.03...
10,010,166
Biotransformation of epomediol. I--Isolation and identification of main metabolites in the rat.
[ -0.001947254640981555, -0.055372580885887146, -0.12900422513484955, -0.01617095246911049, 0.07547586411237717, 0.015095465816557407, 0.07712345570325851, 0.024210745468735695, 0.05108509957790375, 0.05731610208749771, -0.030600782483816147, 0.00832398608326912, -0.020399637520313263, 0.066...
10,010,167
The identification of biotransformation products of the new choleretic drug epomediol in rat has been performed by means of mass spectral, proton magnetic resonance and infrared techniques. The drug was administered perorally or intravenously; urine, bile and faeces were collected and the metabolites isolated. In urine...
[ 0.019758397713303566, -0.12380936741828918, -0.10835061222314835, -0.01409175619482994, -0.007813522592186928, -0.060434721410274506, -0.021001724526286125, 0.08036115765571594, 0.024399016052484512, -0.05504048988223076, -0.008070149458944798, 0.04490281641483307, 0.02980322390794754, 0.0...
10,010,168
Cholest-5-ene-3 beta, 26-diol: synthesis and biomedical use of a deuterated compound.
[ -0.026647258549928665, -0.10191934555768967, 0.013774137012660503, -0.022638536989688873, 0.009260816499590874, -0.06782717257738113, 0.01732059009373188, 0.0515311099588871, -0.007946598343551159, 0.029422754421830177, 0.011945187114179134, 0.003265248378738761, -0.06415456533432007, -0.0...
10,010,169
To further studies of the metabolism of 26-hydroxycholesterol in fetal and neonatal life, a deuterated compound was prepared from kryptogenin by Clemmensen reduction. The spectra of the deuterated 26-hydroxycholesterol showed that five to nine deuterium atoms were incorporated per 26-hydroxycholesterol molecule, with t...
[ -0.009686497040092945, -0.021660802885890007, -0.08123843371868134, -0.05258367210626602, -0.04576665535569191, 0.012222809717059135, -0.07522465288639069, 0.053384989500045776, -0.004390113055706024, -0.012131798081099987, 0.008423634804785252, -0.02250572293996811, -0.041524194180965424, ...
10,010,170
Determination of hydroxypropylhistidine in haemoglobin as a measure of exposure to propylene oxide using high resolution gas chromatography mass spectrometry.
[ 0.08713119477033615, -0.0010802868055179715, -0.0859106183052063, 0.014576496556401253, 0.04696805030107498, 0.05295833945274353, 0.04753774031996727, 0.13585638999938965, -0.06187371164560318, 0.01239855121821165, -0.0023270922247320414, 0.021568572148680687, -0.02760928124189377, 0.00884...
10,010,171
The alkylating agent propylene oxide is a potential carcinogen. Exposure to this compound leads to the formation of N-3'-(2-hydroxypropyl)histidine in protein. A sensitive and specific method has been developed for the determination of this alkylated amino acid in rat and human haemoglobin using high resolution gas chr...
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10,010,172
Conversion of the prosthetic moieties of glutathione pathway conjugates to the corresponding S-acetates.
[ -0.04560089856386185, -0.030283920466899872, -0.12135547399520874, -0.006051790900528431, -0.016520220786333084, 0.03981667757034302, 0.012341348454356194, 0.06664904206991196, -0.015998974442481995, 0.021261809393763542, 0.017064768821001053, 0.004098201170563698, 0.017595523968338966, -0...
10,010,173
A simple acetylation procedure was shown to from S-acetates of the xenobiotic moieties of mercapturic acid pathway metabolites. The S-acetates that were produced were characterized by mass spectrometry or by gas chromatography mass spectrometry.
[ 0.018510133028030396, -0.03066444583237171, -0.1201125904917717, -0.00929776020348072, 0.11507721245288849, 0.06491666287183762, 0.01136893592774868, 0.09368251264095306, 0.04331161454319954, -0.049754977226257324, 0.05086945742368698, -0.05215083435177803, -0.0253735538572073, -0.05297859...
10,010,174
Studies on the metabolism of procarbazine by mass spectrometry.
[ 0.051636796444654465, 0.03175606578588486, -0.14061576128005981, -0.026787420734763145, 0.0035823327489197254, -0.0004665866435971111, 0.024281607940793037, 0.16209465265274048, 0.004018397536128759, 0.08347011357545853, -0.02279120683670044, -0.021125251427292824, -0.02465711534023285, 0....
10,010,175
The mass spectrometric properties of procarbazine and some of its breakdown products were examined using isotopic labeling and high resolution mass spectrometry. A specific intramolecular methyl group transfer, induced by electron impact, was used diagnostically to distinguish between two isomeric derivatives. The mass...
[ 0.04428451135754585, 0.0033262730576097965, -0.09748460352420807, -0.015848014503717422, 0.04160923883318901, 0.030509933829307556, 0.04407671093940735, 0.15588079392910004, 0.020515788346529007, 0.05954423546791077, -0.007734718266874552, 0.007597251795232296, -0.022918645292520523, 0.055...
10,010,176
Inhibition of thymidine incorporation into the DNA of normal and neoplastic cells by a factor from bovine maternal placenta: interaction of the inhibitor with cell membranes.
[ -0.012561975978314877, -0.015605533495545387, -0.04945163056254387, -0.04401208832859993, 0.05032503604888916, 0.021036501973867416, 0.003964869771152735, 0.0769442766904831, 0.005509929731488228, 0.03366294130682945, 0.006235677748918533, 0.03110097162425518, -0.030726909637451172, -0.028...
10,010,177
An inhibitor was isolated from the maternal part of bovine placentas which inhibits the incorporation of [3H]thymidine into the DNA of a variety of tumor cells to a significantly higher degree as compared to normal cells. This protein-type component was labeled by reaction with N-succinimidyl[2,3-3H]propionate, and int...
[ -0.0023303860798478127, -0.09282441437244415, -0.0883607417345047, -0.04735451936721802, 0.0007888653199188411, 0.006827007979154587, 0.028397465124726295, 0.08490670472383499, 0.05424293130636215, 0.008411363698542118, 0.0034930903930217028, 0.016529902815818787, 0.0007297780830413103, 0....
10,010,178
The management of stage I--II Hodgkin's disease with irradiation alone or combined modality therapy: the Stanford experience.
[ 0.016503024846315384, 0.04645320400595665, 0.002317290985956788, 0.027386344969272614, 0.027689944952726364, -0.07070081681013107, 0.050535909831523895, 0.11461006850004196, -0.012521093711256981, -0.00781268160790205, 0.009397552348673344, 0.09080883115530014, 0.06787016242742538, 0.03617...
10,010,179
At Stanford University, between 1968 and 1978, 230 patients with pathologic stage I--II Hodgkin's disease were treated on prospective clinical trials with either irradiation alone or irradiation followed by 6 cycles of adjuvant combination chemotherapy. The actuarial survival at 10 yr was 84% for patients in either tre...
[ 0.049839794635772705, -0.0028005719650536776, -0.04441312327980995, 0.011864752508699894, 0.021369444206357002, -0.03697667643427849, 0.03714725747704506, 0.1557631492614746, 0.029778238385915756, -0.015549548901617527, 0.04438018798828125, 0.11436578631401062, 0.09830794483423233, 0.00984...
10,010,180
Interaction between vaccinia virus and human blood platelets.
[ -0.0461539551615715, 0.05797038599848747, -0.08065008372068405, -0.0313245952129364, -0.07262539863586426, 0.01732279360294342, -0.006626956630498171, 0.05978774279356003, 0.040933169424533844, 0.010050386190414429, -0.032111071050167084, 0.007395613938570023, -0.010949233546853065, 0.0295...
10,010,181
The objective of the present study was to characterize the interaction between human platelets and vaccinia virus and to examine possible impairment of platelet functions. The vaccinia virus was selected for our model system because it lacks detectable neuraminidase activity. Platelets were incubated with purified vira...
[ -0.06333478540182114, -0.013909478671848774, -0.043222956359386444, -0.025283344089984894, 0.003122896421700716, 0.014427606016397476, 0.01848689280450344, 0.08761036396026611, 0.045496657490730286, 0.029208991676568985, -0.004977766424417496, -0.0006801437702961266, 0.008860045112669468, ...
10,010,182
Considerations in the use of B6 vitamers in hematologic disorders: I. Red cell transport and metabolism of pyridoxal.
[ 0.03283243626356125, -0.0912298783659935, -0.1342323124408722, -0.011691240593791008, -0.062380097806453705, 0.07471553236246109, 0.01545706856995821, 0.12804533541202545, 0.033871933817863464, -0.02066725492477417, -0.027582639828324318, 0.050248220562934875, -0.07684668153524399, -0.0045...
10,010,183
Platelet protein organization: analysis by treatment with membrane-permeable cross-linking reagents.
[ -0.03611330687999725, -0.13413690030574799, -0.03396110236644745, -0.024467473849654198, 0.005107456818223, -0.007265510968863964, -0.019796617329120636, 0.08483283221721649, 0.05055553838610649, -0.06849877536296844, 0.011120866052806377, -0.01860111951828003, -0.06842707842588425, 0.0958...
10,010,184
We have examined platelet protein organization by treatment of intact resting or thrombin-activated platelets with two cross-linking reagents, diamide or dithiobis(succinimidyl propionate) (DTSP). Cross-linked complexes were separated by polyacrylamide gel electrophoresis in the absence of reducing agent and their comp...
[ -0.11383675783872604, -0.11311284452676773, -0.01559711154550314, -0.04832693561911583, -0.017531435936689377, -0.039400458335876465, 0.03715365007519722, 0.16041801869869232, 0.05237962305545807, -0.004145199898630381, 0.019879383966326714, 0.02420107275247574, -0.04750552028417587, 0.098...
10,010,185
Immature megakaryocytes in the mouse: physical characteristics, cell cycle status, and in vitro responsiveness to thrombopoietic stimulatory factor.
[ 0.006258048117160797, -0.07781334221363068, -0.04663873463869095, -0.02848283015191555, -0.04953514039516449, 0.007631104439496994, 0.03133599832653999, 0.0994178056716919, -0.041286222636699677, 0.09773357212543488, -0.03190191090106964, 0.035886574536561966, -0.036987416446208954, 0.0535...
10,010,186
The heterogeneity among immature megakaryocytes has been examined by physical properties, cell cycle status, and responsiveness to thrombopoietic stimulatory factor. Three types of immature megakaryocytes exist that can be recognized by acetylcholinesterase staining, nuclear shape, high nucleus/cytoplasm ratio, and sma...
[ 0.028760671615600586, -0.10632394999265671, -0.06429242342710495, -0.07456633448600769, -0.003581404220312834, 0.005295462440699339, -0.024497559294104576, 0.06725902110338211, -0.057815827429294586, 0.04281952232122421, -0.01887357421219349, -0.011386252008378506, -0.03291808441281319, 0....
10,010,187
Sex related differences in platelet function: the effect of aspirin.
[ -0.035509467124938965, -0.026295173913240433, -0.033597998321056366, 0.08249889314174652, -0.061482883989810944, 0.018587525933980942, -0.017147982493042946, 0.07404002547264099, 0.0458347350358963, -0.0639915019273758, -0.009079446084797382, -0.022707078605890274, -0.1254316121339798, 0.0...
10,010,188
There is evidence from clinical studies and animal experiments that aspirin has a greater antithrombotic activity in males compared to females. We investigated platelet function in vitro and in vivo in rabbits before and after the administration of a dose of aspirin (5 mg/kg) which inhibited collagen stimulated thrombo...
[ -0.019330447539687157, -0.051767487078905106, -0.02273138239979744, 0.11122723668813705, -0.05032789707183838, -0.012797333300113678, -0.034018367528915405, 0.10395210236310959, 0.046555012464523315, -0.010030924342572689, -0.03980640694499016, 0.019285326823592186, -0.08845437318086624, 0...
10,010,189
Sideroblastic anemia with markedly increased free erythrocyte protoporphyrin without dermal photosensitivity.
[ -0.04244205355644226, -0.0014161178842186928, -0.06017207354307175, 0.07766100764274597, 0.0633813664317131, -0.0019138682400807738, 0.04268323630094528, 0.053878750652074814, 0.05211063101887703, 0.03197227045893669, 0.030212130397558212, -0.0014890966704115272, -0.09716189652681351, 0.03...
10,010,190
A patient with idiopathic sideroblastic anemia and atypical clinical and biochemical findings is described. He had a greatly increased erythrocyte and plasma protoporphyrin, but normal urine and fecal porphyrins. The erythrocyte protoporphyrin had a fluorescence spectrum typical of free protoporphyrin, but caused no ph...
[ -0.027672840282320976, -0.002678545657545328, -0.07847882062196732, 0.06399326771497726, 0.007489410229027271, -0.06318702548742294, 0.05425051599740982, 0.08946529775857925, 0.008527498692274094, -0.0167077649384737, -0.028880570083856583, -0.008245125412940979, -0.10490848869085312, 0.04...
10,010,191
Erythropoiesis in ha/ha and sph/sph mice, mutants which produce spectrin-deficient erythrocytes.
[ -0.046449899673461914, -0.0547330416738987, -0.050023727118968964, 0.012227118015289307, -0.008746528998017311, -0.00545400008559227, 0.06609559059143066, 0.06864386051893234, -0.03952018916606903, 0.01590847782790661, 0.016707176342606544, -0.022526660934090614, -0.07263463735580444, 0.01...
10,010,192
In order to characterize chronically accelerated erythropoiesis, we studied the ultrastructure of bone marrow and spleen of ha/ha and sph/sph mice, two mutants with profound hemolytic anemia secondary to deficiency of the erythrocyte membrane protein spectrin. The marrows and spleens of both varieties were extremely er...
[ -0.0551702119410038, -0.05899164453148842, -0.08159855753183365, -0.009847760200500488, -0.01913106068968773, 0.015931352972984314, 0.03594590723514557, 0.12764158844947815, 0.012393019162118435, -0.002128560096025467, 0.0012445425381883979, -0.02226182445883751, -0.0686698704957962, 0.038...
10,010,193
Acute leukemia in idiopathic sideroblastic anemia: response to combination chemotherapy.
[ -0.0478895865380764, 0.021810263395309448, -0.05972626432776451, 0.02118549309670925, -0.09599634259939194, -0.03478651121258736, -0.0023354527074843645, 0.08872603625059128, 0.011947929859161377, 0.0006263161194510758, -0.06950283795595169, 0.02134694904088974, -0.0029641168657690287, -0....
10,010,194
Three patients with idiopathic sideroblastic anemia of variable duration developed acute leukemia. In two the leukemia was morphologically and histochemically myeloblastic, in one lymphoblastic. With combination chemotherapy remission was achieved in all three. The remission inductions were complicated by long periods ...
[ 0.0027553692925721407, 0.0024244508240371943, -0.07077621668577194, -0.006535165477544069, -0.07130690664052963, -0.040480438619852066, -0.014088742434978485, 0.11593906581401825, 0.01497516967356205, -0.019380956888198853, -0.08147581666707993, 0.047806210815906525, -0.011129379272460938, ...
10,010,195
Preparation of factor IX deficient human plasma by immunoaffinity chromatography using a monoclonal antibody.
[ 0.037492573261260986, -0.04697646573185921, -0.010990255512297153, 0.018079116940498352, 0.03985217958688736, 0.0015715986955910921, 0.05143957957625389, 0.13502731919288635, -0.023786071687936783, 0.019429897889494896, -0.009610959328711033, -0.026782846078276634, -0.008865190669894218, 0...
10,010,196
A murine hybridoma clone is described that grows continuously in culture and produces a monoclonal antibody we have called Royal Free Monoclonal Antibody to factor IX No. 1 (RFF-IX/1). This has high affinity for a coagulation site on factor IX. RFF-IX/1 immobilised on sepharose can be used to deplete factor IX from nor...
[ -0.01742861233651638, -0.06200123950839043, -0.011930511333048344, -0.03885272890329361, 0.08634582161903381, -0.04330199956893921, 0.047799840569496155, 0.10142388939857483, -0.0070718321949243546, -0.0029132033232599497, -0.020112324506044388, -0.04934980720281601, 0.00583728589117527, 0...
10,010,197
A monoclonal antibody that detects expression of transferrin receptor in human erythroid precursor cells.
[ -0.05590434372425079, -0.08728071302175522, -0.05842966213822365, -0.00903519056737423, 0.05867471173405647, 0.016756802797317505, 0.08315020799636841, 0.03414301201701164, 0.1075468584895134, 0.021801751106977463, -0.027410971000790596, -0.03903765603899956, -0.10978423804044724, 0.057312...
10,010,198
A monoclonal antibody, L5.1, obtained by immunizing a Balb/c mouse with HL60 human promyelocytic leukemia cells, was found to react with both HL60 cells and with the K562(S) cell line. This monoclonal antibody binds and immunoprecipitates a glycoprotein (Mr 87,000) present on the cell surface membrane of K562(S) as a d...
[ -0.09249526262283325, -0.038637351244688034, -0.06388851255178452, -0.06072939559817314, 0.0006609802367165685, 0.008924619294703007, 0.032016217708587646, 0.07538726180791855, 0.09657485783100128, 0.025077059864997864, -0.03678440302610397, 0.041719116270542145, -0.04277466982603073, 0.00...
10,010,199
Congenital erythropoietic porphyria, diminished activity of uroporphyrinogen decarboxylase and dyserythropoiesis.
[ 0.023250577971339226, -0.009329221211373806, 0.021304916590452194, 0.0006804162985645235, -0.10592195391654968, -0.04998933523893356, -0.03241404891014099, 0.002757857320830226, -0.00739218108355999, 0.043784212321043015, -0.06912153214216232, 0.006506940349936485, -0.08727161586284637, 0....
10,010,200
Evidence of the existence of a factor that induces Fc receptors on bone marrow cells.
[ -0.036016836762428284, -0.06216011196374893, -0.0672207772731781, 0.0172417089343071, -0.0062417807057499886, 0.08233436197042465, -0.0059786210767924786, 0.15504024922847748, 0.09184294193983078, 0.09804710745811462, -0.058275822550058365, -0.016063576564192772, -0.011324873194098473, 0.0...
10,010,201
The existence of a molecule responsible for the induction of Fc receptor (FcR) on bone marrow cells (FcR inducer, FcRI) is demonstrated in conditioned media from the macrophage-like cell line WR19M.1 activated by bacterial lipopolysaccharides. The molecular weight obtained from molecular sieving chromatography in gel a...
[ -0.04103546217083931, -0.11206787079572678, -0.06244003772735596, -0.020063476637005806, -0.032195523381233215, 0.07182101905345917, 0.015339088626205921, 0.1453174650669098, 0.054934896528720856, 0.06200417876243591, -0.02599710039794445, -0.08339425176382065, 0.07301203906536102, 0.10239...
10,010,202
A technique to detect reduced mechanical stability of red cell membranes: relevance to elliptocytic disorders.
[ -0.014114082790911198, -0.13034364581108093, -0.07187794148921967, 0.022705910727381706, -0.08216552436351776, -0.017510592937469482, 0.043303411453962326, 0.0717213973402977, 0.06715679913759232, -0.05853177234530449, -0.04527755081653595, 0.06425534188747406, -0.014396036975085735, -0.00...