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10,011,103 | A total of 1166 male participants (ages 23--80 years) of the Normative Aging Study who had baseline blood pressure less than 140/90 mm Hg were followed prospectively for 10 years. Blood pressures were taken at 5- and 10-year follow-up examinations. Multiple linear regression analysis indicated that baseline levels of s... | [
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10,011,104 | A comparative study of serum lipids between Belgium and Korea. | [
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10,011,105 | Serum cholesterol values are markedly lower in Korea than in Belgium in both males and females. This is attributed to the much lower consumption of saturated fat in Korea. A mean population serum cholesterol value of about 160 mg/dl appears to be compatible with excellent general health and with the absence of ischemic... | [
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10,011,106 | Termination of ventricular tachycardia with ventricular stimulation: salutary effect of increased current strength. | [
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10,011,107 | The effect of increased stimulus current strength on the right ventricular effective refractory period during sustained ventricular tachycardia and on the ability of single premature right ventricular stimuli to terminate ventricular tachycardia was evaluated. Studies were performed during 53 episodes of sustained vent... | [
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10,011,108 | Pulmonary atresia with intact ventricular septum and ventriculocoronary communications: surgical significance. | [
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10,011,109 | The first stage of a repair of pulmonary atresia with intact ventricular septum (type I) was attempted in a 2-day-old infant. At surgery, decompression of the hypertensive small right ventricle was followed by a sudden loss of myocardial contractility and death. Postmortem examination revealed a fistula with a large or... | [
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10,011,110 | Bilateral coronary artery--pulmonary artery fistulas. Report of five cases and review of the literature. | [
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10,011,111 | Detection of mitral ring abscess by two-dimensional echocardiography. | [
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10,011,112 | M-mode and two-dimensional echocardiographic features of mitral ring abscess are described. A round, dense echo mass between the posterior mitral leaflet and left ventricular posterior wall was demonstrated in long- and short-axis views of the left ventricle. The diagnosis of mitral ring abscess was confirmed at surger... | [
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10,011,113 | Pneumonitis and pulmonary fibrosis associated with amiodarone treatment: a possible complication of a new antiarrhythmic drug. | [
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10,011,114 | Six patients are presented who developed pulmonary infiltrates of undetermined origin while being treated for severe ventricular arrhythmias with amiodarone hydrochloride. Biopsy material was available in four patients and revealed interstitial or alveolar fibrosis and pneumonitis. Four patients recovered and two died ... | [
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10,011,115 | Myocardial thallium-201 kinetics. | [
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10,011,116 | Spasm of a normal or minimally narrowed coronary artery in the presence of severe fixed stenoses of the remaining vessels: clinical and angiographic observations. | [
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10,011,117 | Four patients with medically refractory unstable angina are presented. Each patient had ST-segment abnormalities during some episode of pain. Three patients had at least one episode of documented ST-segment elevation with their spontaneously occurring chest pain. One had recurrent ventricular tachycardia. Two patients ... | [
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10,011,118 | Transient qrs changes simulating ami. | [
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10,011,119 | Pulmonic valve motion. | [
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10,011,120 | Rationale of the diet-heart statement of the American Heart Association. Report of Nutrition Committee. | [
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10,011,121 | Gel electrophoresis of maternal and fetal serum cholinesterases from normal pregnancies and of those affected by neural tube defects. | [
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10,011,122 | The cholinesterase isozymes of maternal and fetal sera from normal pregnancies and those in which the fetus had a neural tube defect were studied using flat-bed vertical polyacrylamide gel electrophoresis. Normal maternal and fetal sera had multiple bands of cholinesterase activity, including the two bands in the posit... | [
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10,011,123 | beta-Glucuronidase in gastric aspirate after oral cimetidine in the diagnosis of carcinoma of the stomach. | [
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10,011,124 | The activity of beta-glucuronidase was studied in the gastric aspirate from normal individuals, cases of duodenal ulcer with pyloric stenosis and carcinoma of the stomach. The optimum pH for the activity of this enzyme in the gastric aspirate is 4.0 to 5.5. Cimetidine, a H2-receptor antagonist, was administered orally ... | [
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10,011,125 | A new method of radioimmunoassay by simultaneous filtration using a microharvester. | [
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10,011,126 | Estimation of specific radioactivity of radioimmunoassay tracer by a double-labelling technique. | [
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10,011,127 | Placental protein 5 (PP5) in pregnancy and malignant disease: the influence of heparin binding. | [
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10,011,128 | The molecular mass of immunoreactive placental protein 5 (PP5) in late pregnancy blood was studied by gel filtration. The predominant form of PP5 in serum was of molecular mass 37000, whereas in heparinised plasma the molecular mass ranged upwards from 50000, with the majority of material in high molecular mass forms, ... | [
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10,011,129 | A simple reverse-phase high pressure liquid chromatographic determination of conjugated bile acids in serum and bile using a novel radial compression separation system. | [
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10,011,130 | A new HPLC method for analyzing conjugated bile acids in bile and especially in serum is presented. For separation of novel radial compression system with a 10-cm flexible-walled reverse phase column (RCM-100 Module, Waters Ass.) packed with micro-Bondapak C18 was used. Without any laborious hydrolysis and derivatizati... | [
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10,011,131 | Proposal for the standardization of the serum unsaturated iron binding capacity assay, and results in groups of subjects with normal iron stores and with prelatent, latent, and manifest iron deficiency. | [
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10,011,132 | An effort has been made to standardize the indirect iron saturation excess method for the determination of the serum unsaturated iron binding capacity (UIBC) and thus to relinquish the direct adsorption methods for the assay of the serum total iron binding capacity (TIBC) which give falsely high results due to unspecif... | [
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10,011,133 | Plasma lecithin-cholesterol acyltransferase activities in uraemic patients. | [
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10,011,134 | Plasma lecithin-cholesterol acyltransferase (LCAT) activity was measured in 43 haemodialysis and 15 peritoneal dialysis (CAPD) patients. LCAT activities in both groups of patients were significantly lower than those of normal subjects and did not correlate with any of the other biochemical parameters studied. The effec... | [
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10,011,135 | Rapid determination of ammonia in whole blood and plasma using flow injection analysis. | [
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10,011,136 | A flow injection method for the determination of ammonia in whole blood and plasma is described. The method utilizes diffusion of ammonia into a stream of a pH-sensitive indicator, which is monitored by a photometer. A volume of 90 microliter is needed and the result is obtained within 1 min. Ammonia concentrations inc... | [
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10,011,137 | Radioassay method of neuraminidase towards N-acetylneuraminosyl hexasaccharides. | [
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10,011,138 | We devised a sensitive method to assay for neuraminidase activities towards alpha-(2 leads to 3)-N-acetylneuraminosyl hexasaccharide and alpha-(2 leads to 6)-N-acetylneuraminosyl hexasaccharide, which were isolated from the urine of a patient with adult sialidosis with partial deficiency of beta-galactosidase. Standard... | [
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10,011,139 | Precancerous changes in the larynx. | [
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10,011,140 | Clinical and radiological findings in subjects with unilateral Ménière's disorder. | [
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0.0054... |
10,011,141 | In order to contribute to the knowledge of the possible causes of Ménière's disorder, the authors have conducted systematic studies based on blood analysis and on petrous bone radiological examinations in patients suffering from unilateral Ménière's disorder and in two control groups, one of patients with unilateral su... | [
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0... |
10,011,142 | Selective destruction of the outer hair cells in the chinchilla. | [
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-0.0... |
10,011,143 | In the study of cochlear function an animal model in which apical outer hair cells could be destroyed with retention of inner hair cells would be valuable. Our object was to attempt to reproduce a reported method in a scientific manner. Behavioural response thresholds to pure tones were recorded in 7 monaural chinchill... | [
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0.0081... |
10,011,144 | The cells in tonsillar crypts. | [
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0.03764334321022034,
0.0150... |
10,011,145 | The material lying within the crypts of 11 human palatine tonsils was studied by scanning and transmission electron microscopy. There was a mixture of desquamated epithelial cells and various non-epithelial cells, mainly lymphocytes, with some mononuclear phagocytes and plasma cells, and a few erythrocytes, neutrophil ... | [
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0.0205636415630579,
0.046673595... |
10,011,146 | Retraction of skin flaps. | [
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0.022... |
10,011,147 | Experiments on the pig and the human to measure retraction of skin flaps are described. Animal experiments show that it is dependent on the original length of the flap, and on the original length to breadth ratio for flaps perpendicular to the tension lines. The most important factor is the position of the flap relativ... | [
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10,011,148 | The definition of branchial cysts, sinuses and fistulae. | [
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0.0138... |
10,011,149 | In a study of 57 lateral cervical lesions, 46 cysts were found to form a homogeneous group and four sinuses and fistulae formed another homogeneous group. The cysts lay behind the angle of the mandible, and were lined by stratified squamous epithelium resting on lymphoid tissue, with part of the wall resembling a lymph... | [
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0.05... |
10,011,150 | Surgeon's workshop: a modification of the "pull through' technique of glossectomy. | [
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0.008... |
10,011,151 | Familial inherited abnormalities. | [
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10,011,152 | When is familial genetic? | [
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0.07483039796352386,
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-0.0333434082567691... |
10,011,153 | Disorders of vitamin absorption. | [
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0.0329... |
10,011,154 | Sarcoidosis: an overview II. | [
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0.10... |
10,011,155 | Relative decreased splenic uptake of Tc-99m-sulfur colloid in patients with pancreatic carcinoma. | [
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0.06571655720472336,
0.0071379... |
10,011,156 | Relative spleen/liver activity ratio was determined from posterior projection images using a photodensitometric method. Ratios from scans of 22 patients with proven pancreatic carcinoma (12 from rectilinear scans and 10 from scintillation camera images) were determined and compared to studies from patients documented a... | [
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0.0386... |
10,011,157 | Thyroid steal syndrome? | [
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-0.... |
10,011,158 | A 57-year-old woman with hyperthyroidism had a loud to-and-fro bruit which persisted when the patient was inadvertently rendered hypothyroid with antithyroid drugs. Symptoms suggestive of transient cerebral ischemia prompted an angiographic study which demonstrated both normal cerebral circulation and an enormous incre... | [
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0.00028379078139550984,
-0.0508... |
10,011,159 | Multiple "cold" areas demonstrated on bone scintigraphy in a patient with neuroblastoma. | [
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0.03842717781662941,
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10,011,160 | A "cold" or photopenic defect on bone scintigraphy is a well recognized phenomenon and has been described in several conditions affecting bone. An unusual case of multiple "cold" defects in a patient with stage IV neuroblastoma is presented. A follow-up scan with the patient in clinical remission shows resolution of th... | [
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10,011,161 | Hemobilia detected by Tc-99m labeled red blood cells. | [
-0.016545742750167847,
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-0.030322670936584473,
... |
10,011,162 | Tc-99m labeled red blood cells were successfully used to determine the site of hemorrhage in a 67-year-old man with hemobilia. A false hepatic artery aneurysm was confirmed at angiography and ultimately successfully embolized. The relative merits of using Tc-99m labeled red blood cells for detecting sources of upper ga... | [
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-0.051135674118995667,
-0.019905349239706993,
... |
10,011,163 | Hepatobiliary imaging with Tc-99m-IDA radiopharmaceuticals. | [
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0.02167765237390995,
0.08784735947847366,
0.10543521... |
10,011,164 | An unusual cause of an isolated, focal splenic defect demonstrated by liver-spleen scintigraphy. | [
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0.... |
10,011,165 | Metastatic involvement of the spleen is uncommon. Lymphoma is the most common cause of primary and secondary malignant lesions of the spleen, whereas splenic metastases from carcinoma are rare and usually occur in a setting of concomitant carcinomatosis with melanoma, breast, ovary and lung accounting for the principal... | [
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0.01139685045927763,
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10,011,166 | Leaking Glenn anastomosis demonstrated by first pass radionuclide angiography. | [
-0.014192786999046803,
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0.02179926447570324,
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0.06390036642551422,
0.099934... |
10,011,167 | First pass radionuclide angiography was used to demonstrate a leaking Glenn anastomosis at the superior vena cava--right atrial junction as well as tricuspid atresia and a ligated persistent left superior vena cava. First pass radionuclide angiography may demonstrate anatomic configurations not obvious at cardiac cathe... | [
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0.05068883299827576,
0.0... |
10,011,168 | Hepatobiliary imaging of common bile duct obstruction by a hydronephrotic kidney. | [
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0... |
10,011,169 | A patient with intermittent right upper quadrant abdominal pain thought to represent acute cholecystitis had common bile duct obstruction due to an enlarged right renal pelvis. A Tc-99m-HIDA scan provided the first clue to the diagnosis. The case reinforces the value of cholescintigraphy in diagnosing pathology outside... | [
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0.042... |
10,011,170 | Complementary role of reticuloendothelial and hepatobiliary imaging agents in the assessment of liver disease. | [
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10,011,171 | The merit of concomitant hepatic imaging with Tc-99m-sulfur colloid (SC) and Tc-99m-HIDA was examined in 40 patients with abnormal liver function tests. The studies were performed sequentially within a 2 to 5 day interval with 5 mCi each of SC or HIDA. Routine static images in all cases, and dynamic studies with HIDA i... | [
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0.02... |
10,011,172 | Splenosis: first scintigraphic demonstration of extensive splenic implants. | [
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0.035517461597919464,
-0.00... |
10,011,173 | Radiation therapy for Hodgkin's disease followed by hypothyroidism and then Graves' hyperthyroidism. | [
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0.030518047511577606,
0.02638963982462883,
-0... |
10,011,174 | Radionuclide cerebral angiographic findings in Paget's disease of the skull. | [
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0.042224254459142685,
0.017... |
10,011,175 | Bone marrow scan and radioiron uptake of an intrathoracic mass. | [
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0.08129171282052994,
0.097624011... |
10,011,176 | Hepatobiliary imaging: intrathoracic activity from herniation of abdominal contents. | [
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0.057228077203035355,
0.08358997851610184,
0.08... |
10,011,177 | Functional asplenia in hemoglobin SE disease. | [
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-0.013089059852063656,
-0.0... |
10,011,178 | Intrapulmonary shunting associated with cirrhosis: incidental diagnosis by perfusion lung scan. | [
0.04205215722322464,
0.015795908868312836,
0.034324731677770615,
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0.009090949781239033,
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0.04597180709242821,
-0.08920497447252274,
0.0675533339381218,
0.075... |
10,011,179 | Ultrasound measurement of contraction response of the gallbladder: comparison with the radionuclide test for cystic duct patency. | [
0.08873499184846878,
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0.015272049233317375,
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0.0240015871822834,
-0.007134984713047743,
0.0608244463801384,
0.... |
10,011,180 | Two tests of cystic duct patency were compared in 37 patients with suspected acute cholecystitis. Ultrasound (US) measurement of gallbladder contraction induced by 40 Ivy dog units of cholecystokinin (CCK) was followed by the radionuclide (RN) test for cystic duct patency. In all 13 patients in whom US showed significa... | [
0.05496535822749138,
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0.006464863661676645,
0.04122590646147728,
0.0729731097817421,
0.0842... |
10,011,181 | The use of Kr-81m in ventilation imaging. | [
0.022776354104280472,
0.09650090336799622,
0.03216427192091942,
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0.005845020990818739,
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0.0023728476371616125,
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0.02274131402373314,
0.05699784308671951,
0.068674... |
10,011,182 | Radioactive gases are very useful in the study of pulmonary disorders because they allow an assessment of regional lung function. The most widely used radioactive gases are Xe-133 and, more recently, Kr-81m. This paper is a review of the physical characteristics of Kr-81m, its production from the parent Rb-81, the diff... | [
0.025100646540522575,
0.05977607145905495,
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-0.02165844477713108,
-0.013327416963875294,
0.01567670702934265,
0.07893116772174835,
0.072... |
10,011,183 | Demonstration of a colovesical fistula on a bone scan. | [
0.015700360760092735,
0.0037026789505034685,
-0.032619018107652664,
0.027734586969017982,
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-0.03112279251217842,
0.08520108461380005,
0.06355367600917816,
0.0... |
10,011,184 | Scintigraphic evaluation of pulmonary ventilation. | [
0.05004720017313957,
0.08265376836061478,
-0.03998993709683418,
-0.04296635836362839,
-0.007690994068980217,
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-0.08751612901687622,
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0.02843349799513817,
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0.016370028257369995,
0.0005394523032009602,
0... |
10,011,185 | Discordance of sclerosing skeletal secondaries between sequential scintigraphy and radiographs. | [
0.002883641282096505,
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-0.005755114369094372,
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0.002969597466289997,
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0.0353129543364048,
0.05476940795779228,
0.026667162775993347,
-0.010141070000827312,
0... |
10,011,186 | Regression in metastatic lesions as seen on a bone scan may be accompanied by increasing sclerosis radiographically. There are two possible causes for interval radiographic sclerosis: progressive osteoblastic tumor deposition or the healing process itself. The presence of active neoplasia can better be determined in sc... | [
-0.0023664480540901423,
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0.0277062077075243,
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0.02895798720419407,
-0.040263064205646515,
0.12078973650932312,
0.10977765172719955,
0.... |
10,011,187 | Will all new drugs become orphans? | [
-0.01802101545035839,
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-0.036955077201128006,
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0.01697186939418316,
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-0.02688562124967575,
0.08000516891479492,
0.14638647437095642,
0.03586451709270477,
0.0... |
10,011,188 | Cardiocirculatory actions of trimazosin and sodium nitroprusside in ischemic heart disease. | [
0.039325881749391556,
0.0018196206074208021,
-0.01048506610095501,
0.0004208596365060657,
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0.03880348429083824,
-0.004895354155451059,
0.0... |
10,011,189 | Although postload-reducing drugs are effective vasodilators in chronic congestive heart failure, the clinical application of the approach to ambulatory patient management remains difficult. We compared the hemodynamic effects of the new oral systemic vasodilator trimazosin (TZ) with those of nitroprusside (NP). Both TZ... | [
0.033716171979904175,
0.05043076351284981,
-0.02157912403345108,
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0.009333423338830471,
-0.01884225569665432,
0.05196... |
10,011,190 | Age and phenytoin kinetics in adult epileptics. | [
0.05130453407764435,
-0.08103790134191513,
-0.016882795840501785,
0.03080751746892929,
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0.014900833368301392,
0.03506796807050705,
0.04838399589061737,
0.06755657494068146,
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0.004494414199143648,
0.024753883481025696,
-0.00966349896043539,
0.08309... |
10,011,191 | Michaelis-Menten parameters for rate of drug metabolism (Vmax) and serum concentration at which metabolism is half of Vmax (Km) were determined in 92 adult epileptic patients taking phenytoin who were 21 to 78 yr old. The patients received no known inhibitors or inducers of phenytoin metabolism. Results of physical exa... | [
0.0839211493730545,
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0.024892518296837807,
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0.14696472883224487,
0.009395640343427658,
-0.02980702556669712,
0.00921301543712616,
0.020754562690854073,
-0.0026529121678322554,
0.... |
10,011,192 | Clinical kinetics of 1, 4-dihydroxy-5,8-bis [(2-[(2-hydroxyethyl) amino] ethyl] amino ]-9, 10-anthracenedione. | [
0.024311766028404236,
-0.0653315931558609,
0.02190571278333664,
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0.03716137632727623,
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0.03667783364653587,
0.12419132143259048,
0.03953966498374939,
0.02229287289083004,
0.0067690107971429825,
0.01320318877696991,
-0.03617122769355774,
0.104377068... |
10,011,193 | The clinical kinetics of 1, 4-dihydroxy-5,8-bis[[ 2-[(2-hydroxyethyl) amino] ethyl] amino]-9,10-anthracenedione dihydrochloride (DHAQ) are reported. DHAQ, 1 to 3 mg/m2, was administered as an intravenous bolus to six patients with metastatic cancer. Plasma clearance of the drug followed a biphasic pattern with a harmon... | [
-0.009601365774869919,
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-0.01862708292901516,
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0.16443008184432983,
0.03333202749490738,
-0.0184150543063879,
-0.00949765369296074,
0.013524940237402916,
-0.008244956843554974,
0.053... |
10,011,194 | Dose-response relationships for spironolactone at steady state. | [
0.040535423904657364,
-0.06617596745491028,
-0.00040031244861893356,
0.0048578400164842606,
0.0018544484628364444,
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0.0894680917263031,
0.021354811266064644,
-0.04889002814888954,
0.03313649818301201,
0.03520219773054123,
0.05442872270941734,
0.... |
10,011,195 | The overnight urine electrolyte and plasma potassium responses to spironolactone (25, 50, 100, and 200 mg daily) at steady state were investigated in 11 healthy subjects after fludrocortisone challenge. For sodium excretion and urine log10 10 Na/K, log dose-response relationships were defined (P less than 0.001 in each... | [
0.03820051625370979,
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0.01275393646210432,
0.021947549656033516,
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0.08312253654003143,
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-0.029183391481637955,
-0.04877021163702011,
0.08826097846031189,
0.029987599700689316,
0.09... |
10,011,196 | Dipyridamol kinetics. | [
-0.014812922105193138,
-0.06958144903182983,
-0.017536602914333344,
-0.007050685118883848,
0.05404440686106682,
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0.021046621724963188,
0.09625179320573807,
0.03923465311527252,
-0.04527708515524864,
0.05714259669184685,
-0.004834896884858608,
-0.050361547619104385,
0.0... |
10,011,197 | The kinetics of the antiplatelet drug dipyridamole were studied in six normal subjects (three men and three women) who were ages 22 to 34 yr old. Each received 20 mg IV and four also took a 50-mg oral dose. Blood samples were collected after each dose for a period of 3 days and concentrations of dipyridamole were measu... | [
0.0692160427570343,
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0.15244778990745544,
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0.005721257533878088,
0.007227214518934488,
-0.012666220776736736,
0.... |
10,011,198 | Potassium balance in piretanide and digoxin treatment. | [
-0.06325270235538483,
-0.0070459493435919285,
0.004852536600083113,
0.0350118912756443,
-0.07927069813013077,
0.01778583973646164,
0.02101178467273712,
0.03323027119040489,
0.012787933461368084,
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-0.04447031021118164,
-0.02926982194185257,
-0.044978067278862,
-0.005949... |
10,011,199 | Piretanide, a new potent diuretic, was given to 18 healthy male subjects to determine its effect on serum, total body (TBK), and red cell potassium (RCP). TBK and RCP were measured before treatment to establish baseline values, after which all subjects received 6 mg piretanide a day for 14 days. After this period subje... | [
-0.03012070246040821,
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0.03675372153520584,
0.0749289020895958,
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0.009629855863749981,
0.10169070959091187,
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-0.04625682160258293,
-0.06209854036569595,
-0.0008981282007880509,
0.01872003637254238,
0.0... |
10,011,200 | Nonlinear theophylline elimination. | [
-0.07415639609098434,
0.03629454970359802,
0.06778077781200409,
0.028807243332266808,
-0.008236110210418701,
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0.023718880489468575,
0.01692384108901024,
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0.033829107880592346,
0.04066247493028641,
0.0589899942278862,
0.0011827220441773534,
0.051461... |
10,011,201 | Elimination kinetics of theophylline and its major metabolites were investigated in 14 healthy adults in single-dose studies and in a multiple-plateau study. The plasma concentrations of theophylline and the metabolites 3-methylxanthine (3-MX), 1-methyluric acid (1 MU), and 1,3-dimethyluric acid (13-MU) were monitored ... | [
0.04767993465065956,
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0.028674034401774406,
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0.010809443891048431,
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0.18804888427257538,
0.09546196460723877,
-0.04665689170360565,
-0.028431130573153496,
0.026852672919631004,
0.0004884876543655992,
0.068... |
10,011,202 | Hemodynamic effects of diuretics in patients with marked peripheral edema and mild hypertension. | [
-0.021058671176433563,
-0.016694488003849983,
0.08591123670339584,
-0.004067721776664257,
0.020999763160943985,
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0.07209336012601852,
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-0.03894675895571709,
-0.04476024582982063,
0.031781718134880066,
0.011088925413787365,
0.0... |
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