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10,011,503 | The concentrations of estradiol (E2) and 5 alpha-androstane-3 beta, 17 beta-diol (3 beta-Adiol) receptor were quantified in the pituitaries of male rats, aged 15--100 days. The available binding sites were measured directly in pituitary cytosol. E2 receptor levels reached a peak between days 22 and 30 and then declined... | [
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10,011,504 | Release of E prostaglandins into the cerebrospinal fluid and its inhibition by melatonin after cervical stimulation in the rabbit. | [
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10,011,505 | The release of the E type of prostaglandin (PGE) into the cerebrospinal fluid of mature female rabbits was studied using an indwelling catheter in the cisterna magna. The cervix of the rabbit was stimulated 5 min after the central injection of either vehicle or melatonin solution. PGE was measured by RIA, and in unstim... | [
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10,011,506 | Induction and inhibition of uterine vasodilation by catechol estrogen in oophorectomized, nonpregnant ewes. | [
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10,011,507 | Effect of antibodies to estrogen receptor on the binding of 3H-labeled antiestrogens and androstanediol in the uterus. | [
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10,011,508 | We report here the effects of antibodies to estrogen receptor (ER) on the binding of tritiated 5 alpha-androstane-3 beta-17 beta-diol and antiestrogens to receptor in calf uterine cytosol. The antibodies, prepared from a rabbit immunized with purified estradiol-receptor complex from calf uterine nuclei, were found to d... | [
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10,011,509 | Differential regulation by glucocorticoids of proopiomelanocortin mRNA levels in the anterior and intermediate lobes of the rat pituitary. | [
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10,011,510 | Glucocorticoids negatively regulate de novo synthesis of proopiomelanocortin (POMC) and the steady state POMC mRNA levels in the rat pituitary anterior lobe. The POMC system of the intermediate lobe is far less sensitive to alterations in circulating glucocorticoid levels. Possible mechanisms for this differential regu... | [
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10,011,511 | Operative endoscopy today. | [
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10,011,512 | Operative endoscopy permits therapeutic measures to be carried out that spare the patient major surgery. In its narrower sense, operative endoscopy was "inaugurated" with total biopsy of polyps. A complication occasionally seen with polyp-ectomies, namely haemorrhage, provided the impetus for developing endoscopic haem... | [
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10,011,513 | Endoscopic determination of the extent of early ulcerated gastric cancer by the Congo red test. | [
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10,011,514 | The presence of a positive pressure gradient from pancreatic duct to choledochal cyst demonstrated by duodenoscopic microtransducer manometry: clue to pancreaticobiliary reflux. | [
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10,011,515 | A case of choledochal cyst is presented. The diagnosis was established by endoscopic retrograde cholangiopancreatography, which also demonstrated that the common bile duct joined the pancreatic duct at an abnormally long distance from the papilla. Duodenoscopic manometry using a microtransducer catheter showed that the... | [
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10,011,516 | The value of colonoscopy in the diagnosis of lleo-caecal tuberculosis. | [
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10,011,517 | There is no place in gynecological endoscopy for unipolar of bipolar high-frequency current. | [
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10,011,518 | In 1981 we showed that there is a clear relationship between the extent of destruction of the vascular and nervous systems within the mesosalpinx, and the occurrence of menstrual disorders, and menopausal symptoms. Depending upon the individual sterilization technique, varying portions of the tubes are destroyed and co... | [
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10,011,519 | A hand-held otophotographic-system with automatic exposure control. | [
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10,011,520 | Endoscopic fistulo-sphincterotomy: an alternative method of sphincterotomy using a new sphincterotome. | [
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10,011,521 | A new method of endoscopic sphincterotomy (ES) is described when selective cannulation of the common bile duct (CBD) is not possible and a prominent intraduodenal segment of the CBD is endoscopically recognized. A straight retractable sphincterotome was specifically designed to produce an artificial choledochoduodenal ... | [
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10,011,522 | Resection of obstructive bronchial fibrolipoma through the flexible fiberoptic bronchoscope. | [
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10,011,523 | Choledochoduodenal fistula due to tuberculosis. | [
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10,011,524 | Colonoscopic appearance of the remnant of the appendix after total inversion. | [
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10,011,525 | In a series of 395 total colonoscopies, an oblong smooth tumor was seen in the cecum of six patients corresponding to the remnant of the totally inverted appendix. All the patients had undergone a laparotomy during which the appendix was inverted. The histological examination demonstrated a uniform finding without any ... | [
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10,011,526 | Regeneration of rat tracheal epithelium: changes in gap junctions during specific phases of the cell cycle. | [
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10,011,527 | Uninjured mitotically inactive tracheal epithelium has virtually no gap junctions. When the epithelium is stimulated to proliferate synchronously through a single wave of DNA synthesis and cell division, study of thin sections and freeze-fracture replicas by conventional transmission electron microscopy reveals that ga... | [
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10,011,528 | 1,1-Dichloroethylene-induced pulmonary injury. | [
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10,011,529 | Oral administration of 1,1-dichloroethylene (1,1-DCE) produces acute injury to the lungs of C57Bl/6 mice. The bronchiolar epithelium is most severely affected with damage selective for Clara cells. After a 100 mg kg/dose of 1.1-DCE. Clara cells show extensive dilatation of cisternae and degeneration of the endoplasmic ... | [
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10,011,530 | Target organ toxicity: immune system. Arlington, Virginia, October 20-21, 1980. | [
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10,011,531 | Porcine tracheal goblet cell ultrastructure: a three-dimensional reconstruction. | [
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10,011,532 | In order to study specific anatomical relationships among organelles involved in the movement and secretion of mucin granules by airway epithelium, a three-dimensional replica of a single goblet cell from porcine trachea was constructed by means of transmission electron microscopy of serially prepared ultrathin section... | [
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10,011,533 | Methods and approaches for assessing immunotoxicity: an overview. | [
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10,011,534 | The goals of the National Toxicology Program as they relate to immunological evaluation in toxicity assessment are discussed. The advantages of immune function assays for defining cellular injury as subtoxic levels following exposure to general or immunocyte specific chemical toxicants are proposed. A comprehensive scr... | [
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10,011,535 | In vivo assessment of immunotoxicity. | [
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10,011,536 | The organs, tissues, and cells of the lymphoreticular system have received considerable attention as targets for chemicals causing adverse effects. A basic toxicological approach is described for assessing the risk of a chemical perturbing the immune system. CD-1 mice were exposed for 14 or 90 days to one of several ch... | [
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10,011,537 | Application of tumor, bacterial and parasite susceptibility assays to study immune alterations induced by environmental chemicals. | [
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10,011,538 | Model systems to study the effects of chemicals of environmental concern on bacterial and parasitic diseases as well as the immunosurveillance and destruction of transplantable tumor cells were described and evaluated. Studies were conducted in female B6C3F1 mice following adult or pre/postnatal exposure to several pro... | [
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10,011,539 | Use of experimental airborne infections for monitoring altered host defenses. | [
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10,011,540 | The success or failure of the respiratory system to defend itself against airborne infectious agents largely depends upon the efficiency of the pulmonary defenses to maintain sterility and to dispose of unwanted substances. Both specific and nonspecific host defenses cooperate in the removal and inactivation of such ag... | [
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0.08648887276649475,
0.1... |
10,011,541 | Nucleotide sequence and secondary structure of citrus exocortis and chrysanthemum stunt viroid. | [
-0.00842226855456829,
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0.11950217932462692,
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10,011,542 | The complete nucleotide sequence of citrus exocortis viroid (CEV, propagated in Gymura) and chrysanthemum stunt viroid (CSV, propagated in Cineraria) has been established, using labelling in vitro and direct RNA sequencing methods and a new screening procedure for the rapid selection of suitable RNA fragments from limi... | [
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10,011,543 | Glutathione reductase from human erythrocytes. The sequences of the NADPH domain and of the interface domain. | [
-0.05003140866756439,
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0.... |
10,011,544 | 1. Sequence analysis of the NADPH domain (residues 158--293) and of the interface domain (365--478) was based on 12 CNBr fragments, which were isolated using ion-exchange chromatography and paper methods. Fragments with more than 15 residues were digested further with trypsin and chymotrypsin. The isolated peptides wer... | [
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0.047... |
10,011,545 | The effect of pH and D-glycerate 2,3-bisphosphate on the O2 equilibrium of normal and SH(beta 93)-modified human hemoglobin. | [
0.060890812426805496,
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10,011,546 | The present paper reports data for the effect of pH and D-glycerate 2,3-bisphosphate (D-glycerate-2,3-P2) on the oxygen equilibrium of normal and SH(beta 93)-modified human hemoglobin. At sufficiently high D-glycerate-2,3-P2 concentrations, both oxy and deoxy forms of HbA are saturated with the organic phosphate at all... | [
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10,011,547 | Studies on the secondary structure of wheat 5.8 S rRNA. Conformational changes in the A + U-rich stem during ribosome assembly. | [
-0.008633127436041832,
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0.0546... |
10,011,548 | The nucleotide sequence of wheat (Triticum aestivum) 5.8-S ribosomal RNA has been re-examined using partial chemical degradation with high-temperature sequencing gels and oligonucleotide analysis. The results clarify previously ambiguous residues and add two additional nucleotides, G127 and G135, to the sequence. Estim... | [
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10,011,549 | Prediction of secondary structural elements in the phosphatidylcholine-transfer protein from bovine liver. | [
0.010415446944534779,
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... |
10,011,550 | Secondary structural elements of the phosphatidylcholine-transfer protein from bovine liver have been predicted from its primary structure with the aid of two computerized methods. The predicted alpha-helix and beta-strand content have been compared with the values derived from circular dichroism spectra. The hydrophob... | [
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0.06... |
10,011,551 | Disulfide bonds in egg-white riboflavin-binding protein. Chemical reduction studies. | [
0.0027720199432224035,
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0.045889... |
10,011,552 | All eight disulfide bonds in the apo-form of egg white riboflavin-binding protein were easily reduced by 2-mercaptoethanol and dithiothreitol. These bonds exhibited nearly the same reactivity, thus they appeared to be exposed in the native structure, or 'superficial'. The cleavage of protein disulfides resulted in a lo... | [
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0.0... |
10,011,553 | Effect of cations on the acetylation of chromatin in vitro. | [
0.019335128366947174,
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0.00778520992025733,
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10,011,554 | The effect of the differently charged cations Na+, Mg2+, spermidine and spermine on the acetylation of histones in vitro in soluble chromatin and in core particles was investigated. Up to a given concentration, which depends on the charge of the cation, all four cations activate the acetylation of these fractions. Abov... | [
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0.043405931442976,
0.0376... |
10,011,555 | Primary structure of the glycans from human lactotransferrin. | [
-0.017142081633210182,
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... |
10,011,556 | The polypeptide chain of human lactotransferrin possesses two glycoslyation sites to which glycans are linked through an N-(beta-aspartyl)-N-acetylglucosaminylamine bond and which are structurally heterogenous. After chymotryptic or pronase digestions, glycopeptides with five different glycan structures could be isolat... | [
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0.020... |
10,011,557 | Uridylate trapping induced by the C-2-modified D-glucose analogs glucosone, fluoroglucose, and glucosamine. | [
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0.03446513041853905,
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0.02385... |
10,011,558 | Interaction of oxidized and reduced uteroglobin with progesterone. | [
-0.03624006360769272,
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-0.01569... |
10,011,559 | Binding of added progesterone to native uteroglobin requires the reduction of the disulfide bonds that hold together the two polypeptide chains of the protein. The hypothesis that in the native oxidized state of uteroglobin the steroid binding cavity is preformed and occupied by a progesterone molecule has been tested ... | [
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0.0542462021112442,
-0.06417398154735565,
-0.00446460... |
10,011,560 | Purification and characterization of a mannose/glucose-specific lectin from Vicia cracca. | [
0.016990629956126213,
0.009859427809715271,
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0.042... |
10,011,561 | The seeds of Vicia cracca are known to contain two lectins: an N-acetylgalactosamine-binding lectin, which reacts specifically with human erythrocytes of blood group A, and a mannose/glucose-binding lectin unspecific towards human blood groups. The second lectin is the object of the present work. Purification was achie... | [
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0.020290033891797066,
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... |
10,011,562 | Studies on prophospholipase A2 and its enzyme from human pancreatic juice. Catalytic properties and sequence of the N-terminal region. | [
0.02099481411278248,
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0.06177499517798424,
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0.02214747667312622,
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0.0025... |
10,011,563 | Upon tryptic activation of pure human prophospholipase A2, a heptapeptide is released from the N-terminal part of the protein yielding active phospholipase A2 (EC 3.1.1.4). Both the kinetics of the activation process and the amino acid sequence of the activation peptide strongly resemble those of pancreatic zymogens of... | [
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0.0033711998257786036,
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0.13536155... |
10,011,564 | The biosynthesis and linkage of teichuronic acid to peptidoglycan in Bacillus licheniformis. | [
-0.008486002683639526,
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0.0387122668325901,
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0.10621456801891327,
-0.022... |
10,011,565 | Membrane and wall-membrane preparations of Bacillus licheniformis 94 will, if supplied with the appropriate precursors, synthesize teichuronic acid and link it to peptidoglycan although teichuronic acid is absent from walls of this organism. B. licheniformis 94 lacks phosphoglucomutase activity and therefore cannot syn... | [
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0.03928333893418312,
-0.0... |
10,011,566 | Heterogeneity of binding site for adsorptive pinocytosis of simple proteins by rat yolk sacs. | [
0.03799528256058693,
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0.0807520... |
10,011,567 | 1. When rat yolk sacs were incubated in serum-free medium 199, the 125I-labelled forms of both formaldehyde-treated bovine serum albumin and ribonuclease were captured far more rapidly than 125I-labelled polyvinylpyrrolidone. Extensive adsorption of these proteins to the plasma membrane is the main cause of this effect... | [
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0.04660880193114281,
-0.043903451412916183,
0.1406744... |
10,011,568 | Picrate as an inhibitor of photosystem II in photosynthetic electron transport. | [
-0.039124779403209686,
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0.05189167708158493,
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-0.... |
10,011,569 | 2,4,6-Trinitrophenol (picric acid) is an effective inhibitor of photosynthetic electron transport (pI50 value 6.82). By means of artificial donor and acceptor systems its site of inhibition was located at the reducing side of photosystem II. In addition, picric acid also uncouples photophosphorylation but a much higher... | [
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0.08860144019126892,
-0.023320481181144714,
-0.0052426899783313274,
0.01... |
10,011,570 | Purification and characterization of two forms of rat plasma proangiotensin. | [
-0.06913390010595322,
0.015227466821670532,
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0.008052637800574303,
0.028817741200327873,
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0.012263432145118713,
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0.06867... |
10,011,571 | Two forms of rat plasma proangiotensin were purified by (NH4)2SO4 fractionation, chromatography on DEAE-cellulose at pH 6.5, DEAE-Sepharose at pH 8.9, Sephadex G-150, hydroxyapatite and hexyl-agarose. Both forms were finally separated by affinity chromatography on concanavalin-A--Sepharose. Presence or absence of carbo... | [
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-0.07410133630037308,
0.07... |
10,011,572 | 270-MHz 1H nuclear-magnetic-resonance study of met-enkephalin in solvent mixtures. Conformational transition from dimethylsulphoxide to water. | [
-0.026885945349931717,
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0.011954907327890396,
... |
10,011,573 | 1H spectra at 270 MHz of zwitterionic Met-enkephalin pentapeptide (Tyr-Gly-Gly-Phe-Met) in (C2H3)2SO/water mixtures are reported and discussed in terms of solvent-induced conformational transitions. The analysis of the chemical shifts, line widths, coupling constants and rotamer populations around chi 1 and chi 2 sugge... | [
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0... |
10,011,574 | Characterisation of the chick brain high molecular weight multiply phosphorylated microtubule associated protein. | [
0.0318729542195797,
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0.07609707117080688,
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0.005610867403447628,
0.042274605482816696,
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0.05618802... |
10,011,575 | A high-molecular-weight microtubule-associated protein from chick brain, which has previously been shown to be phosphorylated in vitro to the extent of 10-12 mol X mol-1, is shown to have the same properties as reported for the microtubule-associated protein MAP2 from calf and porcine brain in terms of its molecular we... | [
0.03462262824177742,
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0.003755587385967374,
-0.018624322488904,
-0.0018524802289903164,
0.019181111827492714,
0.0717863216996193,
0.0528021864593029,
0.06130608171224594,
0.03835123032331467,
0.025490593165159225,
0.044476546347141266,
0.021748408675193787,
0.135393604... |
10,011,576 | Purification and properties of tryptophan 5-monooxygenase from rat brain-stem. | [
-0.021302873268723488,
-0.01645970530807972,
-0.038252439349889755,
0.0146200405433774,
0.056476105004549026,
0.07553786039352417,
-0.023250605911016464,
-0.024055490270256996,
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0.05843184515833855,
-0.017146240919828415,
-0.00916021503508091,
-0.055810872465372086,
0... |
10,011,577 | Tryptophan 5-monooxygenase was purified approximately 5,500-fold, to apparent homogeneity with a specific activity of 374 nmol min-1 mg-1 at 30 degrees C, from rat brain-stem using Sepharose CL-6B, DEAE-Sepharose CL-6B and pteridine-agarose chromatography. Two distinct active forms were separable by DEAE-Sepharose CL-6... | [
-0.045471444725990295,
-0.1047675609588623,
-0.067525714635849,
-0.0029380025807768106,
-0.0025123890955001116,
0.04774586856365204,
0.007829147391021252,
0.03312842547893524,
0.0027127452194690704,
0.036381468176841736,
0.024965887889266014,
-0.015682678669691086,
0.017469720914959908,
0.... |
10,011,578 | Concentration dependence of the order-disorder transition of carrageenans. Further confirmatory evidence for the double helix in solution. | [
-0.021092673763632774,
-0.11722637712955475,
0.006644302047789097,
0.029596665874123573,
-0.008168996311724186,
0.06805621087551117,
-0.06794437766075134,
0.032735664397478104,
0.10941029340028763,
0.03199641779065132,
0.09436562657356262,
0.05610879138112068,
-0.051933374255895615,
0.0643... |
10,011,579 | The temperature-induced changes in optical rotation which are associated with the order-disorder transition of carrageenans have been analysed to investigate the concentration dependence and hence to attempt to derive the number of polysaccharide chains involved in the ordered species at equilibrium. The consequences o... | [
-0.028271181508898735,
-0.14607009291648865,
0.015187378041446209,
0.010021046735346317,
-0.04605830833315849,
0.03515436500310898,
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0.026667481288313866,
0.13278916478157043,
0.07992514967918396,
0.07382137328386307,
0.045210596174001694,
0.004606215283274651,
0.0494... |
10,011,580 | Fragmentation and modification of iota-carrageenan and characterisation of the polysaccharide order-disorder transition in solution. | [
-0.03938360884785652,
-0.10446064919233322,
0.028247734531760216,
0.015401843935251236,
0.05482970178127289,
0.0398993045091629,
-0.017613397911190987,
0.026379495859146118,
0.11898390203714371,
0.04685050994157791,
0.041445013135671616,
0.051912881433963776,
-0.06505087018013,
0.069690249... |
10,011,581 | A procedure is described in detail by which the algal polysaccharide, iota-carrageenan, can be modified and fragmented to products of more regular structure and shorter chain length. Since most chains of this product can form uninterrupted helices they undergo the disorder-order transition without the gelation that is ... | [
-0.06692904233932495,
-0.13037890195846558,
-0.022744791582226753,
-0.008569168858230114,
-0.010328679345548153,
0.0274179857224226,
0.02282470464706421,
0.027142755687236786,
0.09458661079406738,
0.036380648612976074,
0.052430734038352966,
0.09595446288585663,
-0.0012080599553883076,
0.02... |
10,011,582 | The nature of the binding for prothrombinase at the platelet surface as revealed by lipolytic enzymes. | [
-0.08213267475366592,
-0.08185100555419922,
-0.08853999525308609,
-0.04935097321867943,
-0.03249780461192131,
0.012683323584496975,
0.042677368968725204,
0.12702234089374542,
0.032872654497623444,
-0.009878668934106827,
-0.03791836276650429,
-0.044187281280756,
-0.11872805655002594,
0.0361... |
10,011,583 | The nature of the receptor for the prothrombinase complex at the surface of non-activated platelets was investigated by measuring the platelet prothrombin-converting activity wih a chromogenic substrate assay, after treatment of the platelets with various phospholipases or three different proteolytic enzymes. Platelet ... | [
-0.05752556771039963,
-0.0679926723241806,
-0.08880359679460526,
-0.027178088203072548,
0.0164538212120533,
0.010455871000885963,
0.010496924631297588,
0.12246541678905487,
0.0467713363468647,
0.017498789355158806,
0.01378663256764412,
-0.038632795214653015,
-0.04525827616453171,
0.1084956... |
10,011,584 | Intracellular compartmentation and control of alanine metabolism in rat liver parenchymal cells. | [
0.03477717190980911,
-0.07179257273674011,
-0.03621545061469078,
-0.022943779826164246,
-0.022784320637583733,
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0.01713167503476143,
0.022165730595588684,
0.03653177618980408,
0.08070959150791168,
-0.043892841786146164,
-0.0028961915522813797,
-0.020214973017573357,
0... |
10,011,585 | Isolation, purification, and chemical analysis of the lipopolysaccharide and lipid A of Acinetobacter calcoaceticus NCTC 10305. | [
-0.14873753488063812,
-0.1027837023139,
-0.11190202832221985,
0.012028062716126442,
-0.09041383862495422,
0.08243566751480103,
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0.025989273563027382,
0.032577965408563614,
0.007123768795281649,
0.01493068877607584,
-0.07686050981283188,
0.02532726712524891,
-0.0288224... |
10,011,586 | The lipopolysaccharide of Acinetobacter calcoaceticus NCTC 10305 (London) was obtained by a modified phenol/chloroform/light petroleum method from the bacterial cells and from the culture medium in yields of 1.6% and 2.2% respectively (based on the bacterial dry weight). On chemical analysis, both preparations proved t... | [
-0.09076470136642456,
-0.13438941538333893,
-0.09115663170814514,
-0.025033794343471527,
-0.04581248760223389,
0.09305877983570099,
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0.07786635309457779,
0.005519914906471968,
0.04586828127503395,
-0.005308952648192644,
-0.07160422950983047,
0.07588784396648407,
-0.02... |
10,011,587 | Conformational studies of G-actin containing bound lanthanide. | [
-0.04577995836734772,
-0.16721093654632568,
-0.026445329189300537,
-0.059881750494241714,
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0.030263839289546013,
0.03552205488085747,
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0.01973080076277256,
0.03079751506447792,
0.03883180022239685,
-0.04371984302997589,
0.005... |
10,011,588 | The presence of bound Ln ions gives rise to changes in the ultraviolet absorbance of G-actin. Previously, Ln ions have been shown to mobilize the adenosine moiety of ATP bound to the actin monomer. The changes in ultraviolet absorbance appear to be fully attributable to this mobilization. Any structural changes induced... | [
-0.08126552402973175,
-0.17109990119934082,
0.05133093520998955,
-0.06677954643964767,
0.034424785524606705,
0.004109012428671122,
0.10041674971580505,
0.08412759006023407,
0.08409643918275833,
0.11092238873243332,
0.050032686442136765,
-0.005152818746864796,
-0.08872298896312714,
0.109918... |
10,011,589 | Kinetic investigation of the alpha-chymotrypsin-catalyzed hydrolysis of peptide substrates. The relationship between the peptide structure C-terminal to the cleaved bond and reactivity. | [
0.028660690411925316,
-0.05363849923014641,
-0.06505925953388214,
-0.022959766909480095,
0.08701267093420029,
0.05024557188153267,
-0.027441810816526413,
0.055532306432724,
0.05754397064447403,
-0.022725902497768402,
-0.028478547930717468,
-0.0231705941259861,
-0.10316886007785797,
0.10930... |
10,011,590 | Peptide substrates of the general structure Ac-Tyr-Ly1-Ly2-..-Lym-NH2 and Ac-Phe-Ly1-NH2 have been synthesized and subjected to alpha-chymotrypsin-catalyzed hydrolysis to collect information on the interactions between the enzyme active site and the amino-acid residues Ly1, Ly2, etc., C-terminal to the susceptible bond... | [
-0.026607602834701538,
-0.0997152030467987,
-0.06708651781082153,
-0.03792876377701759,
0.10965989530086517,
0.034804049879312515,
-0.06226249784231186,
0.0676584392786026,
0.05131988227367401,
-0.015603951178491116,
0.04192912578582764,
-0.02350432798266411,
-0.03135710954666138,
0.121226... |
10,011,591 | Photoaffinity labeling of chromatin. Synthesis and properties of arylazido derivatives of 9-aminoacridine: potential photolabels for chromatin studies. | [
-0.0504644475877285,
-0.07883331924676895,
-0.1325019896030426,
0.004235397558659315,
0.01921914890408516,
0.03362761437892914,
0.07498550415039062,
0.040372151881456375,
0.007617502938956022,
0.019800176844000816,
0.05545562505722046,
0.024049220606684685,
0.032392386347055435,
0.09373926... |
10,011,592 | The syntheses and properties of potential photoaffinity labels for the proteins in chromatin studies are described. One compound, N,N'-bis-(9-acridinyl)-4-aza-4-(4-azidobenzoyl)-1,7-diaminoheptane dihydrochloride, has been studied more closely. This photolabel shows high affinity towards DNA (Ka approximately 3 x 10(5)... | [
0.004824677482247353,
-0.01931815966963768,
-0.13749343156814575,
-0.011689146049320698,
0.02640281617641449,
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0.07277525216341019,
0.025200221687555313,
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0.0011646890779957175,
0.040521040558815,
0.0040422407910227776,
0.031511541455984116,
0.066... |
10,011,593 | The complete nucleotide sequence of the chicken ovotransferrin mRNA. | [
-0.10807547718286514,
-0.12885023653507233,
-0.05377984046936035,
0.025103570893406868,
0.010663211345672607,
0.016191111877560616,
-0.04982727766036987,
-0.002505867276340723,
0.20425944030284882,
-0.0758594274520874,
0.020286021754145622,
0.04726630076766014,
-0.12286651879549026,
-0.006... |
10,011,594 | The nucleotide sequence of an almost double-stranded cDNA copy [Cochet, M., Perrin, F., Gannon, F., Krust, A., Chambon, P., McKnight, G. S., Lee, D. C., Mayo, K. E., and Palmiter, R. D. (1979) Nucleic Acids Res. 6, 2435-2452] of chicken ovotransferrin (conalbumin) mRNA has been determined. Taking into account the previ... | [
-0.1375020444393158,
-0.14331093430519104,
-0.05773629620671272,
-0.024715159088373184,
0.04014238715171814,
0.029017791152000427,
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0.025478893890976906,
0.1579555869102478,
-0.053137753158807755,
0.055845171213150024,
-0.008826890960335732,
-0.09016259759664536,
-0.01... |
10,011,595 | High-resolution 1H-NMR spectroscopy of free and glycosidically linked O-acetylated sialic acids. | [
-0.03050115704536438,
-0.11724820733070374,
-0.03914608061313629,
0.04072621837258339,
0.09094837307929993,
0.042264942079782486,
-0.028816035017371178,
-0.0012705741683021188,
0.0831213891506195,
-0.07813336700201035,
0.06318579614162445,
0.03577493876218796,
-0.07964988052845001,
-0.0174... |
10,011,596 | A number of naturally occurring and synthetic, partially O-acetylated derivatives of N-acetylneuraminic and N-glycoloylneuraminic acids have been investigated by 360-MHz 1H-NMR spectroscopy. O-Acetylation causes strong downfield shifts for the resonances of neighbouring sugar-skeleton protons. The chemical shifts of th... | [
0.028521353378891945,
-0.1235491931438446,
-0.10284332931041718,
-0.04334501177072525,
-0.002867487957701087,
0.025645803660154343,
-0.06264343857765198,
0.045170754194259644,
0.07851498574018478,
-0.10879507660865784,
0.06927827000617981,
0.05810583382844925,
-0.07716666162014008,
-0.0850... |
10,011,597 | The central tryptic fragment of histones H1 and H5 is a fully compacted domain and is the only folded region in the polypeptide chain. A thermodynamic study. | [
0.023636043071746826,
-0.0682118684053421,
0.0006590863922610879,
-0.057330429553985596,
-0.000014745055523235351,
0.007726504001766443,
-0.0036953247617930174,
0.05249938741326332,
-0.007459800690412521,
0.01637120731174946,
0.030337277799844742,
-0.018741639330983162,
-0.06430056691169739,... |
10,011,598 | Scanning microcalorimetry has been used to show that the globular structure in histones H1 and H5 melts reversibly over a relatively narrow temperature range as a single domain with enthalpy of melting very close to the van't Hoff enthalpy. These proteins therefore exhibit macroscopic cooperativity like that of many we... | [
-0.10115569829940796,
-0.08222712576389313,
-0.010281436145305634,
0.009667710401117802,
0.04590517282485962,
0.009485749527812004,
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0.03298714756965637,
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0.047086767852306366,
-0.01603022962808609,
-0.05982418730854988,
-0.010531856678426266,
0.0... |
10,011,599 | Conformational changes in subunit A of cholera toxin following the binding of ganglioside to subunit B. | [
0.0066681127063930035,
-0.1186438575387001,
-0.03648817911744118,
-0.02434849739074707,
-0.029102539643645287,
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0.03538202866911888,
0.054554812610149384,
-0.030429357662796974,
0.021694427356123924,
-0.006861540023237467,
0.042355068027973175,
0... |
10,011,600 | 1. Cholera toxin has been labelled with the fluorescent probe 4-chloro-7-nitrobenzofuran (Nbf-Cl) in both subunits, and the labelled subunits separated by gel-permeation. They retained their biological activities. 2. Addition of ganglioside GM1 (which binds to subunit B only) to either labelled subunit did not alter th... | [
0.015508269891142845,
-0.10338525474071503,
-0.008508079685270786,
-0.043774548918008804,
0.07362151890993118,
-0.06805785000324249,
0.018737155944108963,
0.013605279847979546,
0.05860782414674759,
-0.038633886724710464,
-0.007961604744195938,
0.022469835355877876,
0.025224486365914345,
0.... |
10,011,601 | A new mechanism for the reabsorption of thyroid iodoproteins: selective fluid pinocytosis. | [
-0.03533695265650749,
-0.08144564926624298,
-0.0008249079110100865,
0.030296746641397476,
0.06652326881885529,
-0.037830203771591187,
0.09547357261180878,
-0.012101789936423302,
-0.0027167960070073605,
-0.01572100818157196,
-0.01663164235651493,
0.05285296216607094,
-0.05025039613246918,
0... |
10,011,602 | Rat thyroid hemilobes were incubated in presence of exogeneous, heterologous and homologous thyroglobulins. The median density of the thyroglobulin molecules originally added to the medium was compared with that of the molecules remaining at the end of a three-hour incubation period (37 degrees C). A certain degree of ... | [
0.04955277219414711,
-0.09367799758911133,
-0.051516178995370865,
-0.02963448502123356,
0.058458972722291946,
0.04369194060564041,
0.0714309811592102,
0.07071004807949066,
-0.015355370007455349,
0.08425157517194748,
-0.03079548478126526,
0.07214435189962387,
-0.024861348792910576,
0.048856... |
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