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10,001,800 | Fibronectin in human bronchopulmonary lavage fluid. Elevation in patients with interstitial lung disease. | [
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10,001,801 | Fibronectin is a major adhesive and opsonic glycoprotein found in plasma and tissues. Because this molecule appears to mediate a number of interactions between cells and extracellular matrix, and because the interstitial lung disease are characterized by marked derangements of the pulmonary extracellular matrix, we eva... | [
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10,001,802 | Fc and C3 receptors induced by herpes simplex virus on cultured human endothelial cells. | [
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10,001,803 | The mechanism by which immune complexes deposit in vascular tissue is uncertain. Several human viruses, including herpes simplex virus, have recently been demonstrated to replicate in human endothelial cells. Such viruses may injure vascular tissue and could play a role in the pathogenesis of immune complex deposition.... | [
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10,001,804 | Uroporphyrin I stimulation of collagen biosynthesis in human skin fibroblasts. A unique dark effect of porphyrin. | [
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10,001,805 | Porphyria cutanea tarda and erythropoietic porphyria are disorders of heme synthesis that originate in the liver and bone marrow, respectively. Each is characterized by increased accumulation of uroporphyrin, I, by cutaneous photosensitivity, and in some patients by indurated plaques and scarring that resemble sclerode... | [
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10,001,806 | Immunoglobulin G3 subclass production by rheumatoid synovial tissue cultures. | [
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10,001,807 | The cellular infiltrate in the deeper layers of the rheumatoid synovium produces a substantial amount of immunoglobulin (Ig)G. Culture supernatants of synovial tissues from 31 patients with rheumatoid arthritis (RA) undergoing joint replacement or synovectomy have been analyzed for the subclass of IgG present. IgG3 was... | [
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10,001,808 | Urinary concentration in the papillary collecting duct of the rat. Role of the ureter. | [
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10,001,809 | Urine was observed to flow intermittently in the collecting ducts of the extrarenal papilla of antidiuretic rats. The purpose of this investigation was to test Reinking and Schmidt-Nielsen's hypothesis that intermittent flow plays an important role in the production of maximally concentrated urine. Samples of collectin... | [
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10,001,810 | Effect of ouabain on total vascular capacity in the dog. | [
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10,001,811 | Whereas the cardiac effects of digitalis glycosides have been extensively studied, less is known of the extracardiac effects of the drug, in particular the effects on vascular capacity. We investigated the effects of parenteral ouabain on vascular capacity in the dog with particular emphasis on transhepatic resistance ... | [
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10,001,812 | Mechanism of glomerulotubular balance in the setting of heterogeneous glomerular injury. Preservation of a close functional linkage between individual nephrons and surrounding microvasculature. | [
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10,001,813 | Autologous immune complex nephropathy (AICN), an experimental model for human membranous glomerulopathy, is characterized by marked heterogeneity in function from glomerulus to glomerulus. However, the fraction of the filtered load of fluid reabsorbed by the proximal tubule remains nearly constant from nephron to nephr... | [
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10,001,814 | Myocardial kinetics of thallium-201 after dipyridamole infusion in normal canine myocardium and in myocardium distal to a stenosis. | [
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10,001,815 | The purpose of the present study was to define myocardial and blood thallium-201 (Tl-201) kinetics after infusion of dipyridamole in normal canine myocardium and in myocardium distal to a coronary artery stenosis. Miniature radiation detector probes were implanted in the left ventricle in 39 open-chest dogs. A balloon ... | [
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10,001,816 | Inactivation of S-adenosylhomocysteine hydrolase during adenine arabinoside therapy. | [
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10,001,817 | To assess for possible inhibition of cellular transmethylation during adenine arabinoside (ara-A) therapy, S-adenosylhomocysteine hydrolase activity was analyzed in 10 patients with chronic hepatitis B virus infection. In six patients receiving ara-A, enzyme activity was suppressed to 0-2% of control erythrocyte enzyme... | [
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10,001,818 | Renal ammoniagenesis in an early stage of metabolic acidosis in man. | [
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10,001,819 | Total renal ammonia production and ammonia precursor utilization were evaluated in patients under normal acid-base balance and in patients with 24-h NH4Cl acidosis by measuring (a) ammonia excreted with urine and that added to renal venous blood, and (b) amino acid exchange across the kidney. In 24-h acidosis not only ... | [
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10,001,820 | Lactate and glucose exchange across the forearm, legs, and splanchnic bed during and after prolonged leg exercise. | [
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10,001,821 | The net exchange of glucose and lactate across the leg and the splanchnic bed and the arterialdeep venous (A-DV) differences for these substrates in the forearm were determined in healthy subjects during 3-3.5 h of leg exercise (bicycle ergometer) at 58% maximum O(2) uptake and during a 40-min post-exercise recovery pe... | [
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10,001,822 | Human alveolar macrophage cytophilic immunoglobulin G-mediated phagocytosis of protein A-positive staphylococci. | [
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10,001,823 | Human alveolar macrophages (AM) have recently been reported to ingest and kill a strain of Staphylococcus (502A) in the absence of opsonins. To further investigate the mechanism of non-opsonic recognition, we studied phagocytosis of 23 clinical and laboratory strains of S. aureus and Staphylococcus epidermidis by AM, a... | [
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10,001,824 | On the detection of a tone masked by two tones. | [
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10,001,825 | We reopen the question of an appropriate representation to describe the masking of a site midway in frequency between two sine maskers. We suggest that when the maskers are closely spaced in frequency signal detection is mediated by differences in the stimulus envelope caused by the target signal. We show that in previ... | [
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10,001,826 | A quantitative analysis of the interactions of antipneumococcal antibody and complement in experimental pneumococcal bacteremia. | [
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10,001,827 | The mechanism of protection of type-specific antipneumococcal antibody and complement in bacteremia was investigated with purified rabbit antibody and a guinea pig model of pneumococcal bacteremia. IgG and IgM were isolated from the sera of rabbits immunized with type 7 pneumococci (Pn), and their binding to Pn was qua... | [
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10,001,828 | Change in the pitch of a complex tone following its association with a second complex tone. | [
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10,001,829 | The pitch of a high-frequency complex stimulus was changed and maintained in the direction of the pitch of a low-frequency complex stimulus with which it was associated. Six observers made pitch matches for a pitch-shift stimulus (1250-1450-1650 Hz) before and after simultaneous presentation of this stimulus with the f... | [
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10,001,830 | Short-term release cues to stop-consonant place of articulation in child speech. | [
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10,001,831 | In recent work Blumstein and Stevens (J. Acoust. Soc. Am. 66, 1001-1017 (19179); 67, 648-662 (1980) have proposed that the short-term onset spectra at stop-consonant releases provide invariant cues for the perception of place of articulation, and that the salient acoustic characteristics of these cues can be characteri... | [
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10,001,832 | Long-term average speech spectra for normal and hearing-imparied adolescents. | [
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10,001,833 | Acoustical aspects of the speech of hearing-imparied persons have usually been examined over brief periods of time for simple utterances. Of interest in this study was whether abnormal acoustical patterns would be observed when speech was examined over longer periods of time. Spectra were averaged for 20 hearing-impair... | [
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10,001,834 | Carbon monoxide levels in athletes during exercise in an urban environment. | [
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10,001,835 | Aspirin desensitization in aspirin-sensitive asthmatic patients: clinical manifestations and characterization of the refractory period. | [
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10,001,836 | Thirty aspirin-sensitive asthmatic patients underwent incremental, oral aspirin challenge until a "positive reaction" (delta FEV1 greater than or equal to 25%) occurred. After this reaction, aspirin was readministered in an attempt to achieve "desensitization." This was defined as the ability of the patient to ingest 6... | [
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10,001,837 | Methacholine-induced cutaneous flare response: bivariate analysis of responsiveness and sensitivity. | [
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10,001,838 | Cutaneous reactions to allergens exhibit a sigmoid dose-response relationship. Available methods for evaluating the allergen skin-test response do not adequately account for the sigmoid curve. Methodologic factors handicap quantitative studies of allergens based on skin-test reactivity. This problem was evaluated with ... | [
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10,001,839 | Antigenic and allergenic changes during storage of a pollen extract. | [
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10,001,840 | The changes that occur in the antigens and allergens of a timothy grass pollen extract during storage were measured by radioallergosorbent test (RAST) inhibition, isoelectric focusing, (IEF), crossed immunoelectrophoresis (CIE) and crossed radioimmunoelectrophoresis (CRIE) and a dye-binding protein assay. Storage inter... | [
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10,001,841 | Occupational asthma caused by nickel sulfate. | [
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10,001,842 | A 28-yr-old man developed asthma shortly after being exposed to nickel sulfate (NiSO4) in a metal-plating factory. Recordings of peak expiratory flow rates at work and for an off-work period showed increased variations at work, with best values on weekends. Allergy prick skin tests elicited an immediate reaction with N... | [
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10,001,843 | Food system for Space Shuttle Columbia. | [
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10,001,844 | The Space Shuttle's food system consists of food products preserved by dehydration, thermostabilization, irradiation, and moisture control. A preassembled standard menu is provided for each crew member. This is supplemented with a pantry food supply. In case of emergency, the pantry is a contingency food source, but on... | [
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10,001,845 | Development differences in the conceptualization of obesity. | [
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10,001,846 | Development differences in the conceptualization of obesity were investigated in children ranging in age from 5 to 11 years. Perceived causes, cures, and attitudes about obesity were assessed through individual interviews. Answers differed in content as well a complexity. A preliminary category system was developed to ... | [
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10,001,847 | Energy intake and nutrition counseling in cystic fibrosis. | [
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10,001,848 | Historically, it has been thought that the patient with cystic fibrosis (CF) has a voracious appetite. It is now becoming apparent that many patients do not have caloric intakes which meet their full energy requirements. Our study of CF patient, utilizing, a five-day written record of food consumptions and direct obser... | [
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10,001,849 | The entry-level generalist dietitian: I. Employer's general opinions of the adequacy of educational preparation in administration. | [
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10,001,850 | Data were collected from 350 hospital food service directors regarding their general perceptions of the adequacy of preparation in administration provided in the internship (I), coordinated undergraduate (C), traineeship (T), and advanced degree (A) programs. Most employers (93 percent) said that they believed that the... | [
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10,001,851 | The entry-level generalist dietitian: II. Employers' perceptions of the adequacy of preparation for specific administrative competencies. | [
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10,001,852 | Data were obtained from 269 employers of entry-level dietitians regarding their specific perceptions of the importance and adequacy of preparation for 69 administrative competencies provided in internship (I), coordinated undergraduate (C), traineeship (T), and advanced degree (A) programs. Sixty-three competencies wer... | [
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10,001,853 | Soup-to-nuts: a television approach to nutrition education. | [
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10,001,854 | Soup-to-Nuts is a fresh approach to nutrition education. Television is a relatively untapped medium in the classroom for teaching nutrition concepts. These open-ended lessons facilitate discussion and encourage critical analysis of food behavior. Soup-to-Nuts can serve as a model for other audiovisual nutrition educati... | [
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10,001,855 | Food cooperative shoppers: nutrition, knowledge, attitudes, and concerns. | [
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10,001,856 | A study of the nutrition knowledge and attitudes of shoppers in a new kind of cooperative food store indicated shoppers were primarily interested in cooperatives because of the food: its believed superiority in terms of growing conditions, freedom from processing, or nutritional value. Shoppers were skeptical of proces... | [
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10,001,857 | Relative metatarsal length patterns in hallux abducto valgus. | [
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10,001,858 | A modification of the Hohmann procedure for surgical correction of hallux abducto valgus. | [
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10,001,859 | Ultrasonography evaluation for ruptured Achilles tendon. | [
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10,001,860 | Idiopathic erysipelas. A case presentation. | [
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10,001,861 | Osteomyelitis and the natural history of disease. A model for approaching podiatric disorders. | [
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10,001,862 | Acute hematogenous osteomyelitis. A case report. | [
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10,001,863 | Neuropathy, angiopathy, and sepsis in the diabetic foot. Part three: sepsis. | [
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10,001,864 | A simplified preoperative evaluation for Akin osteotomy. | [
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10,001,865 | Synthetic skin. A new adjunct in the treatment of diabetic ulcers. | [
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10,001,866 | Central metatarsal shortening following osteotomy and its clinical significance. | [
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10,001,867 | Z- and M-band appearance in different histochemically defined types of human skeletal muscle fibers. | [
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10,001,868 | In order to define ultrastructural features, which alone or in combination with other features could be used to identify different types of fibers in human skeletal muscle, frozen biopsy specimens of m. tibialis anterior were serially sectioned. The thawed sections were prepared either for enzyme histochemistry or for ... | [
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10,001,869 | Simultaneous Feulgen densitometry and autoradiographic grain counting with the Quantimet 720D image-analysis system. I. Estimation of nuclear DNA content in 3H-thymidine-labeled cells. | [
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0.001... |
10,001,870 | Simultaneous Feulgen densitometry and autoradiographic grain counting with the Quantimet 720D image-analysis system. II. Automated grain counting. | [
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0.004789... |
10,001,871 | A Quantimet 720 Image-Analysis System has been configured and programmed to enumerate silver grains over labeled nuclei in Feulgen-stained autoradiographs. The accuracy and reproducibility of the estimates have been documented in 3H-thymidine (3HTdR)-labeled rat kidney cell cultures. The Quantimet and visual grain coun... | [
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10,001,872 | Aluminum phosphate visualisation of acid phosphatase activity: a biochemical and x-ray microanalysis study. | [
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10,001,873 | A new method is described that demonstrates acid phosphatase activity in the cells of the proximal tubules of the rat kidney. The method is based on the formation of an insoluble aluminum phosphate precipitate. Microanalysis was used to demonstrate the presence of intracellular aluminum and determine the quantity prese... | [
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0.040506232529878616,
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0.017343131825327873,
0.06415341794490814,
... |
10,001,874 | Binding affinities of anti-acetylcholine receptor autoantibodies in myasthenia gravis. | [
-0.009115898981690407,
-0.0908799022436142,
-0.03479776158928871,
0.01874142698943615,
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0.03157171234488487,
0.016879897564649582,
-0.0971921905875206,
-0.0013190213358029723,
0.06... |
10,001,875 | Effect of immune complexes on human neutrophil phagocytic function. | [
-0.030562808737158775,
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0.014779229648411274,
0.030638573691248894,
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0.008663440123200417,
-0.08539394289255142,
-0.07815314829349518,
0.030084138736128807,
0.09... |
10,001,876 | Immune suppression induced by Actinobacillus actinomycetemcomitans. I. Effects on human peripheral blood lymphocyte responses to mitogens and antigens. | [
-0.027677617967128754,
-0.06741731613874435,
0.001160613726824522,
0.018551213666796684,
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0.0840127021074295,
0.0765288919210434,
0.11808867007493973,
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0.033441636711359024,
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-0.016432540491223335,
0.07500337809324265,
0.06780... |
10,001,877 | Tumoricidal macrophages isolated from liver granulomas of Schistosoma mansoni-infected mice. | [
0.045956362038850784,
0.003300617914646864,
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0.05062669888138771,
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0.03146343305706978,
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-0.023647161200642586,
0.12486445158720016,
0.0132... |
10,001,878 | In murine schistosomiasis, inflammatory macrophages (M phi) are a major cell type of the granulomata that encase eggs of the tropical helminth Schistosoma mansoni as they are deposited in the liver by adult worm pairs. The granulomatous response is vigorous during acute infection (8 wk) and spontaneously undergoes immu... | [
0.02973656728863716,
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0.018411003053188324,
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0.061065200716257095,
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-0.013082328252494335,
0.11436299979686737,
0.0205... |
10,001,879 | Immunochemical studies on thymosin: radioimmunoassay of thymosin alpha 1. | [
-0.010994401760399342,
0.04212622344493866,
-0.05526569113135338,
-0.02405615523457527,
0.05767637863755226,
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0.06891179084777832,
0.006585091818124056,
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0.005476769525557756,
0.06... |
10,001,880 | A sensitive and specific radioimmunoassay (RIA) has been developed to measure thymosin alpha 1 in human blood and tissue extracts. Thymosin alpha 1, originally isolated from bovine thymosin fraction 5, has an identical primary structure in bovine and human species. Antiserum to synthetic thymosin alpha 1 was prepared i... | [
-0.010266457684338093,
-0.05200595781207085,
-0.060719043016433716,
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0.1256607472896576,
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0.09926801919937134,
-0.011004053056240082,
0.011350933462381363,
-0.058659423142671585,
0.094... |
10,001,881 | Genetic control of autoimmune disease: interactions between xid and Ipr. | [
-0.0848795473575592,
0.010924930684268475,
0.04674141854047775,
-0.027976620942354202,
0.02700669877231121,
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0.06332383304834366,
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0.037079133093357086,
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0.007445183582603931,
-0.05063037946820259,
0.006165... |
10,001,882 | A genetic experiment has been performed in mice to test the B cell "hyperactivity" hypothesis of autoantibody production. A backcross was designed such that some progeny carried both the sex-linked recessive gene xid, which markedly reduces the B cell hyperactivity and autoantibody production seen in NZB mice, and the ... | [
-0.06344059109687805,
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0.028566349297761917,
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-0.01453924085944891,
0.00... |
10,001,883 | Arming of mononuclear phagocytes by eosinophil peroxidase bound to Staphylococcus aureus. | [
0.027860920876264572,
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0.056217677891254425,
0.003724075388163328,
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0.01095537468791008,
0... |
10,001,884 | When eosinophil peroxidase (EPO) was incubated with Staphylococcus aureus (staph) approximately 40% remained firmly bound to the bacteria as indicated by guaiacol assay. The staph-EPO complex was killed readily by concentrations of H2O2 and a halide that did not alter the viability of control (non-EPO-coated) organisms... | [
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0.11675646156072617,
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0.042795728892087936,
0.... |
10,001,885 | Experimental allergic encephalomyelitis (EAE) in mice: primary control of EAE susceptibility is outside the H-2 complex. | [
-0.032400861382484436,
-0.035612910985946655,
0.0865950956940651,
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0.005218985956162214,
0.03068... |
10,001,886 | We report here the results of EAE induction in 1758 mice from 9 inbred strains, 5 H-2 congenic strains, and 6 F1 hybrids. EAE responsiveness is under the primary control of genes outside the H-2 complex. The F1 data do not show a unifactorial inheritance of EAE responsiveness. The F1 data do imply a maternal factor, se... | [
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0.01897469535470009,
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-0.0067... |
10,001,887 | Thioglycollate-elicited mouse peritoneal macrophages are less efficient than resident macrophages in antibody-dependent cell-mediated cytolysis. | [
0.031316127628088,
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0.04667016491293907,
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0.09294581413269043,
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0.031683482229709625,
0.026090262457728386,
0.042780... |
10,001,888 | Peritoneal macrophages (M phi) obtained after i.p. injection of Brewer thioglycollate medium (TG) were substantially less efficient than resident (R) M phi in an assay of antibody-dependent cell-mediated cytolysis (ADCC) in which 51Cr-labeled sheep erythrocytes were used as target cells. The TG-M phi did not display an... | [
0.010626942850649357,
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0.025129392743110657,
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0.1475689709186554,
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0.09669246524572372,
-0.04402492567896843,
0.027299096807837486,
0.018294844776391983,
0.042546... |
10,001,889 | Lymphokine-mediated microbistatic mechanisms restrict Chlamydia psittaci growth in macrophages. | [
0.004247106611728668,
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0.08590230345726013,
-0.0007242748397402465,
0.01570967026054859,
0.06363491714000702,
0.03549... |
10,001,890 | The obligate intracellular procaryote Chlamydia psittaci replicated in cultures of macrophages taken from the peritoneal cavities of unstimulated or thioglycollate-elicited A/J mice. When treated with supernatant fluids (lymphokines) from C. psittaci-immune mice spleen cells that were stimulated for 24 hr in vitro by t... | [
-0.04500065743923187,
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0.06782390922307968,
0.01879662089049816,
0.006789890117943287,
0.08511195331811905,
0.03900... |
10,001,891 | The effect of adjuvant immunotherapy on tumor recurrence after segmental resection of carcinogen-induced Wistar/Furth primary bowel adenocarcinomas. | [
0.014000006020069122,
-0.04168622940778732,
0.04567132890224457,
0.022566774860024452,
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0.08061143755912781,
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0.03590439632534981,
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0.11367948353290558,
0.012572307139635086,
-0.000... |
10,001,892 | Platelet-activating factor (PAF) in experimentally-induced rabbit acute serum sickness: role of basophil-derived PAF in immune complex deposition. | [
0.0621672198176384,
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0.040553342550992966,
0.03316529095172882,
0.009782904759049416,
0.07528091222047806,
0.06693428754806519,
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0.015610689297318459,
0.0365719199180603,
0.02550703100860119,
-0.01935550943017006,
-0.042136307805776596,
0.04637448489... |
10,001,893 | Immunosuppressive effects of mouse seminal plasma components in vivo and in vitro. | [
-0.04401269182562828,
0.0591370053589344,
-0.02838764898478985,
-0.03388373553752899,
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0.08125438541173935,
0.07362622767686844,
0.0317518375813961,
0.08363302797079086,
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0.10112728923559189,
-0.08013012260198593,
0.0595187582... |
10,001,894 | Mouse seminal plasma (SP), a mixture of aqueous extracts of prostate, seminal vesicle, and epididymis, exerts potent immunosuppressive effects in vivo. The SP mixture completely suppressed both primary and secondary humoral immune responses in mice to low immunizing doses of antigen (bovine serum albumin or washed epid... | [
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0.022058110684156418,
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0.10243602842092514,
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0.035453442484140396,
0.0652657225728035,
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0.06536393612623215,
-0.020676223561167717,
0.082... |
10,001,895 | Mouse brain: an immunologically privileged site for natural resistance against lymphoma cells. | [
0.019719766452908516,
0.046199653297662735,
0.02247246541082859,
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0.05842777341604233,
0.02311282977461815,
0.032941292971372604,
0.053071245551109314,
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-0.013015703298151493,
0.01853334531188011,
-0.048... |
10,001,896 | Lysosomal enzyme release from human monocytes in response to particulate stimuli. | [
-0.009541775099933147,
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0.059800270944833755,
0.029993126168847084,
0.09509844332933426,
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0.056576263159513474,
0.042395804077386856,
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0.05967334657907486,
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-0.03989474102854729,
0... |
10,001,897 | Lysosomal enzyme release from human monocytes was evaluated in response to opsonized zymosan, opsonized sheep erythrocytes, and latex beads. Monocytes were found to release lysosomal enzymes immediately upon challenge with all three phagocytosable particles. Cytochalasin B enhanced beta-glucosaminidase release from mon... | [
-0.011150297708809376,
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0.019590584561228752,
0.05991493538022041,
0.0004976406926289201,
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0.13019083440303802,
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0.04238137602806091,
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0.049105122685432434,
-0.010954930447041988,
0.... |
10,001,898 | Clonotypes of anti-phosphocholine antibodies induced with Proteus morganii (Potter). II. Heterogeneity, class, and idiotypic analyses of the repertoires in BALB/c and A/HeJ mice. | [
-0.017392117530107498,
-0.027899276465177536,
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0.06549923866987228,
0.09858779609203339,
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0.04146227240562439,
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-0.010435550473630428,
0.... |
10,001,899 | The heterogeneity of the PC-specific IgG response of Proteus morganii (Potter) was systematically analyzed. Serum samples from individual mice were focused in paired adjacent tracks, PC-specific antibodies were detected with 125I-PC-RNase, and the resulting autoradiographs were examined for co-focusing bands. Both the ... | [
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0.10979359596967697,
0.08550012856721878,
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0.03320551663637161,
-0.011334570124745369,
-0.06165425851941109,
-0.021157601848244667,
0.057... |
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