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10,001,600 | Donated food staples available to hospitals under federal program. | [
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10,001,601 | Design trick: guessing right for a future that's anybody's guess. | [
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10,001,602 | Correlation between in vivo anti-Pseudomonas and anti-Candida activities and clearance of carbon by the reticuloendothelial system for various muramyl dipeptide analogs, using normal and immunosuppressed mice. | [
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10,001,603 | A linear correlation coefficient analysis, comparing in vivo anti-infective and reticuloendothelial stimulating activity of several different analogs of N-acetylmuramyl-L-alanyl-D-isoglutamine (muramyl dipeptide) suggests that the macrophage is an important target cell for these immunomodulating compounds. The increase... | [
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10,001,604 | N-acetyl muramyl dipeptide stimulation of bone resorption in tissue culture. | [
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10,001,605 | N-Acetyl-muramyl-L-alanyl-D-isoglutamine (MDP), a structurally defined fragment of bacterial peptidoglycan, stimulated significant release of previously incorporated 45Ca from fetal rat bones in tissue culture over the concentration range of 0.1 to 10.0 micrograms/ml. MDP-Stimulated bone resorption was not inhibited by... | [
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10,001,606 | Transfer of resistance with syphilitic immune cells: lack of correlation with mitogenic activity. | [
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10,001,607 | Hamsters infected intradermally with Treponema pallidum Bosnia A develop extensive chronic skin lesions, usually accompanied by metastatic lesions involving the paws, lips, and anal region and by lymph nodes teeming with treponemes. Throughout the course of syphilitic infection, cells from the inguinal lymph nodes resp... | [
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10,001,608 | Comparison fo agglutinin titers for Streptococcus mutans in tears, saliva, and serum. | [
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10,001,609 | The agglutinin titers for three Streptococcus mutans serotypes (AHT, BHT, and 10449, representing serotypes a, b, and c, respectively) were measured in the saliva, tears, and serum of 19 human subjects. Naturally occurring S. mutans agglutinins were routinely present in all fluids tested in the absence of overt local s... | [
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10,001,610 | Dual role of the immune response in street rabiesvirus infection of mice. | [
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10,001,611 | The cellular and humoral immune responses of mice to footpad injection of salivary gland suspensions of street rabiesvirus were investigated. Suppression of these responses with cyclophosphamide both increased the overall mortality rate from (50 to 100%) and delayed onset of disease signs and death for 1 to 2 weeks. De... | [
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10,001,612 | Effect of nitrogen mustard on natural history of right-sided streptococcal endocarditis in rabbits: role for cellular host defenses. | [
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10,001,613 | Cellular host defenses are considered to be ineffective in bacterial endocarditis; the microorganisms in infected vegetations are protected from phagocytic cells by dense layers of fibrin. To test this hypothesis, nitrogen mustard-induced agranulocytosis and leukopenia were produced in rabbits with right-sided streptoc... | [
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10,001,614 | Characterization of an inducible bacteriophage from a leukotoxic strain of Actinobacillus actinomycetemcomitans. | [
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10,001,615 | A bacteriophage, designated phi Aa17, was isolated by mitomycin C induction from leukotoxic Actinobacillus actinomycetemcomitans strains 651. Electron microscopy of the virus revealed particles with regular, nonelongated, polyhedral heads, and tails consisting of a contractile sheath and core. Spikes emanated from the ... | [
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10,001,616 | Ultrastructure of Gram-negative cotton bacteria with different pulmonary toxicities. | [
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10,001,617 | The shedding of outer membrane material was observed by electron microscopy in typical gram-negative cotton bacteria, except Agrobacterium sp. This finding is in accordance with the relative pulmonary toxicities of these bacteria. The presence of capsules did not seem to be correlated with the acute pulmonary toxicity ... | [
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10,001,618 | Depression of monocyte and polymorphonuclear leukocyte oxidative metabolism and bactericidal capacity by influenza A virus. | [
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10,001,619 | Decreased host defense against bacterial disease associated with influenza infection may be related to virus-induced changes in phagocytic cell function. Influenza A virus initiates the respiratory burst in peripheral blood monocytes and polymorphonuclear leukocytes, with a peak chemiluminescent response approximately ... | [
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10,001,620 | Fungistatic capacity of sera from guinea pigs injected with various iron solutions: differences between Trichophyton mentagrophytes and Rhizopus oryzae. | [
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10,001,621 | The fungistatic capacity and serum ion levels (SI) of guinea pigs given subcutaneous injections of various iron solutions were examined. The administration of 2.0 ml of 0.1 M ferric ammonium sulfate, ferric sulfate, or ferric chloride subcutaneously had no significant effect on the SI 3 h after administration, whereas ... | [
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10,001,622 | Genetic control of Propionibacterium acnes-induced protection of mice against Babesia microti. | [
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10,001,623 | Using various strains of inbred mice, we found that Propionibacterium acnes-induced protection against the hemoprotozoan parasite Babesia microti was controlled by a dominant gene(s) not linked to the major histocompatibility gene (H2) complex of mice. P. acnes-induced resistance to infection was not merely an amplific... | [
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10,001,624 | Neutrophil chemotaxis by Propionibacterium acnes lipase and its inhibition. | [
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10,001,625 | The chemoattraction of Propionibacterium acnes lipase for neutrophils and the effect of lipase inhibitor and two antibiotic agents on the chemotaxis were evaluated. Of the various fractions tested, partially purified lipase (fraction 2c) was the most active cytotaxin produced by P. acnes. Serum mediators were not requi... | [
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10,001,626 | Cytotoxin of Pasteurella haemolytica acting on bovine leukocytes. | [
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10,001,627 | The toxicity of Pasteurella haemolytica culture supernatant for bovine and porcine cells was evaluated by 51Cr release. Sterile bacterial culture supernatant was toxic for bovine pulmonary lavage cells, peripheral blood lymphocytes and neutrophils, and cultured peripheral blood mononuclear cells, resulting in marked 51... | [
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10,001,628 | Correlation of the development of acoustic trauma to the intensity and time of acoustic overstimulation. | [
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10,001,629 | Distribution and significance of norepinephrine in the lateral cochlear wall of pigmented and albino rats. | [
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10,001,630 | Picogram quantities of norepinephrine were found in cochlear regions of pigmented and non-pigmented rats. These regions of the cochlea were the modiolus, organ of Corti--osseous spiral lamina and the lateral cochlear wall. The content of norepinephrine in the modiolus and lateral cochlear wall of the pigmented rat was ... | [
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10,001,631 | Acoustic reflex after experimental lesions to inner and outer hair cells. | [
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10,001,632 | Chronic effects of noise or kanamycin on the acoustic intra-aural reflex in nonanesthetized rabbits were studied. The intra-aural reflex activity was simultaneously recorded in both ears upon alternate stimulation of the left and the right side. The inner ears were analyzed in scanning and transmission electronmicrosco... | [
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10,001,633 | Cochlear microphonic evidence for mechanical propagation of distortion products (f2 - f1) and (2f1 - f2). | [
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10,001,634 | The present cochlear microphonic (CM) study was undertaken to help resolve a conflict in the literature regarding cochlear nonlinear properties. The CM studies of Dallos and his coworkers have concluded that "(up to 70-80 dB SPL [re 20 mu Pa]), all orders of distortion components...do not seem to be accompanied by trav... | [
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10,001,635 | Corresponding effects of acoustic fatigue on the cochlear microphonic and the compound action potential. | [
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10,001,636 | Moderate levels of acoustic fatigue, usually induced by a 100 dB SPL pure tone at a frequency appropriate to the location of intracochlear differential electrodes, have a surprising and paradoxical influence on the cochlear microphonic and the compound action potential of the auditory nerve. While the low-level microph... | [
0.023911843076348305,
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0.03719780966639519,
0.003931955434381962,
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0.0036116... |
10,001,637 | An electronmicroscopic study of microtubules in the development of marginal cells of the mouse stria vascularis. | [
0.07844992727041245,
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0.01989... |
10,001,638 | This study provides an ultrastructural evaluation of cytoplasmic microtubules during the maturation of marginal cells of the mouse stria vascularis. Postnatal marginal cells are cuboidal in structure and over a period of days develop the numerous cellular processes typical of transporting epithelia. Immediately after b... | [
0.021189488470554352,
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0.0540... |
10,001,639 | Corresponding effects of hypoxia on the cochlear microphonic and the compound action potential. | [
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0.026... |
10,001,640 | Mild hypoxia has an unexpected influence on the compound action potential (CAP) compared to its effect on the cochlear microphonic (CM). While the CM decreases in amplitude near threshold, the low-level CAP increases in amplitude by as much as 400% and decreases in latency and width. The magnitude of latency decrease i... | [
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0.017... |
10,001,641 | Relationship between temperature and growth rate of bacterial cultures. | [
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0.09565962... |
10,001,642 | The Arrhenius Law, which was originally proposed to describe the temperature dependence of the specific reaction rate constant in chemical reactions, does not adequately describe the effect of temperature on bacterial growth. Microbiologists have attempted to apply a modified version of this law to bacterial growth by ... | [
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0.11242... |
10,001,643 | Iron transport in Mycobacterium smegmatis: Uptake of iron from ferric citrate. | [
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0.0459158755838871,
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10,001,644 | In mycobacterial growth medium 40 to 400 microM citrate was required to solubilize 2 microM 55Fe. This solubilized 55Fe was taken up into both iron-deficient and iron sufficient washed cell suspensions of Mycobacterium smegmatis and Mycobacterium bovis BCG. Although the 55Fe was taken up into the cell, the citrate was ... | [
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10,001,645 | Peptidoglycan of Rhodopseudomonas viridis: partial lack of N-acetyl substitution of glucosamine. | [
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0.09... |
10,001,646 | A lack of at least 70% of N-acetyl substitution of glucosamine in the glycan strands of the peptidoglycan from the gram-negative bacterium Rhodopseudomonas viridis is reported. A disaccharide, very likely GlcN beta(1 leads to 4) Mur, was observed in hydrolysates of the isolated peptidoglycan. The disaccharide was not o... | [
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0.07242... |
10,001,647 | Physiological characteristics of Thiomicrospira sp. Strain L-12 isolated from deep-sea hydrothermal vents. | [
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10,001,648 | Growth of the obligately chemolithotrophic Thiomicrospira sp. strain L-12, isolated from a hydrothermal vent at a depth of 2,550 m in the Galapagos Rift region, was optimal at pH 8 and required 200 mM Na+ and divalent ions (Ca2+ and Mg2+). The organism was microaerophilic and tolerated 300 microM sulfide without a decr... | [
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0.0105... |
10,001,649 | Purification and properties of pyruvate kinase from Streptococcus mutans. | [
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0.0080... |
10,001,650 | Pyruvate kinase (EC 2.7.1.40) from Streptococcus mutans strain JC2 was purified, giving a single band on sodium dodecyl sulfate-polyacrylamide gel electrophoresis. The molecular weight of the native enzyme was 180,000 to 190,000, and the enzyme was considered to consist of four identical subunits. This enzyme was compl... | [
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0.02... |
10,001,651 | Possible association of segregated lipid domains of Mycoplasma gallisepticum membranes with cell resistance to osmotic lysis. | [
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0.023536864668130875,
0.02... |
10,001,652 | Freeze-fracturing of cholesterol-rich Mycoplasma gallisepticum membranes from cells grown in a medium containing horse serum revealed particle-free patches. The patches appeared in cells quenched from either 4 or 37 degrees C. Particle-free patches also occurred in membranes of cells grown in a serum-free medium supple... | [
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0.02301817759871483,
0.01621231995522976,
-0.019... |
10,001,653 | Spontaneous protoplast formation in Methanobacterium bryantii. | [
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10,001,654 | Methanobacterium bryantii was found to undergo rapid lysis when grown in a prereduced chemically defined medium under H2-CO2 (4:1, vol/vol). The addition of 20 mM MgCl2 to the medium gave, rather than rapid lysis, a gradual formation of phase-dark spherical bodies which in thin section appeared as true protoplasts. In ... | [
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10,001,655 | Exospore formation in Methylosinus trichosporium. | [
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0.03802... |
10,001,656 | Formation of exospores in Methylosinus trichosporium was examined by electron microscopy; serial sectioning was used to visualize the shape and location of the developing exospore in relation to the vegetative cell. The initial stage was the formation of a budlike enlargement on one end of the vegetative cell. The enla... | [
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0.057... |
10,001,657 | Production of deferriferrioxamines B and E from a ferroverdin-producing Streptomyces species. | [
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0.01107... |
10,001,658 | When Streptomyces sp. strain Wak. A-305 is cultured in iron (III)- or cobalt (II)-containing media, tris(p-vinylphenyl-4-hydroxy-3-nitrosobenzoato-N3, O4)ferrate(II) (ferroverdin) or the analogous tris-cobalt(III) complex, respectively, is produced intracellularly. In contrast, when cultured in transition metal ion-lim... | [
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0... |
10,001,659 | Induction of 3-hydroxybenzoate 2-hydroxylase in a Pseudomonas testosteroni mutant. | [
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0.07... |
10,001,660 | Benzoate was established as the inducer of a unique 3-hydroxybenzoate 2-hydroxylase activity found in a Pseudomonas testosteroni mutant which is unable to grow on m-hydroxybenzoate as its sole source of carbon and energy. | [
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0... |
10,001,661 | Methylamine uptake in Pseudomonas species strain MA: utilization of methylamine as the sole nitrogen source. | [
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0.0... |
10,001,662 | The uptake of methylamine as the sole nitrogen, but not carbon, source by Pseudomonas sp. strain MA was investigated. Under these growth conditions, a high-affinity, low-capacity uptake system was present having a Km of 16 microM and Vmax of 2 nmol.min-.mg (dry weight) of cells that was competitively inhibited by ammon... | [
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0.056852... |
10,001,663 | Lipoteichoic acid, a major amphiphile of Gram-positive bacteria that is not readily extractable. | [
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0.0666... |
10,001,664 | Commonly used procedures effected the extraction of only 10% of the lipoteichoic acid of stationary-phase cells of Staphylococcus aureus and Streptococcus faecium, unless the cells were first disrupted. | [
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0.... |
10,001,665 | Glycolipids from some extreme thermophilic bacteria belonging to the genus Thermus. | [
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-0.0056629725731909275,
... |
10,001,666 | The lipids of Thermus aquaticus YT1, Thermus thermophilus HB8, Thermus sp. strains H and J (from Icelandic hot springs), and Thermus sp. strain NH (from domestic hot water) have been investigated. Each strain contained two major components, a glycolipid and a glycophospholipid, which have been isolated and analyzed. Al... | [
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-0.09626676887273788,
-0.04905301332473755,
0... |
10,001,667 | Physostigmine treatment of acute phencyclidine intoxication. | [
0.04972543194890022,
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0.054839033633470535,
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0.03860919177532196,
0... |
10,001,668 | Involuntary admission--a century of experience. | [
0.02745242230594158,
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0.11383769661188126,
0.044942062348127365,
0.039044033735990524,
0.016852... |
10,001,669 | Anxiety and mitral valve prolapse syndrome. | [
0.05404752492904663,
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0.04735080897808075,
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0.05200273171067238,
0.09992032498121262,
0.04685501754283905,
-0.062976... |
10,001,670 | The diagnosis of Mitral Valve Prolapse Syndrome (MVPS), even though symptomatically similar to anxiety neurosis, may prompt pharmacological treatment only, neglecting any underlying emotional problems. If only a dichotomy were considered, one diagnosis might be seen as mutually exclusive of the other. A case history is... | [
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0.042826760560274124,
0.04981377348303795,
-0.034... |
10,001,671 | A trial of dextroamphetamine in patients with involutional agitated depression. | [
0.0003096759901382029,
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0.032860275357961655,
0.055427055805921555,
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0.06544149667024612,
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0.0... |
10,001,672 | Unusual presentation of manic depressive disorder in adolescence. | [
-0.04275820776820183,
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0.0739830732345581,
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0.03205941617488861,
-0.0003079693124163896,
-0.007188333664089441,
0.045530... |
10,001,673 | The importance of drug use histories in a series of alcoholics. | [
0.04331005737185478,
0.02013406530022621,
-0.037699248641729355,
0.0013408837839961052,
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0.05742460861802101,
-0.09416805952787399,
0.0763... |
10,001,674 | Visions of snakes. | [
-0.012490959838032722,
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0.071995310485363,
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0.03719298914074898,
0.012891169... |
10,001,675 | The histamine-induced skin reaction in schizophrenic and normal subjects. | [
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0.09590... |
10,001,676 | Most published data on histamine skin tests on schizophrenic patients show them to be insensitive relative to normals or other psychotic patients. However, experimental conditions have varied and in most cases only a single dose of histamine was used. We have compared 13 volunteer controls and 16 paranoid schizophrenic... | [
0.09018560498952866,
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0.024621320888400078,
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0.03580762445926666,
0.0847778... |
10,001,677 | Chemical characterization of thymosin beta 4. | [
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0.... |
10,001,678 | As part of our ongoing investigations on the endocrine thymus, we have isolated and purified to homogeneity a hormone-like peptide which we have termed thymosin beta 4. Thymosin beta 4 has Mr = 4982 and an isoelectric point of 5.1. The complete amino acid sequence of this polypeptide has been established by automated E... | [
0.00021312932949513197,
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0.07382986694574356,
0.007226143032312393,
0.015541969798505306,
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0.06... |
10,001,679 | Characterization of polynucleotide phosphorylase from Micrococcus luteus and isolation of the 13,000 base poly(A) product of the polymerization reaction. | [
-0.02732977271080017,
-0.09436874836683273,
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0.07785917073488235,
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0.07916020601987839,
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0.060... |
10,001,680 | A new purification procedure for polynucleotide phosphorylase from freeze-dried Micrococcus luteus cells gives approximately 20% yield of nearly homogeneous, primer-independent enzyme which is free of nucleic acid. The physicochemical properties of M. luteus polynucleotide phosphorylase are similar to those previously ... | [
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0.03166931867599487,
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0.07280772179365158,
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0.0... |
10,001,681 | Estrogen-induced changes in chick oviduct membrane glycoproteins. | [
-0.032635923475027084,
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0.08115186542272568,
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0.004426... |
10,001,682 | Membrane protein and glycoprotein changes during estrogen-induced differentiation of the chick oviduct were studied. Membrane preparations from chicks treated with diethylstilbestrol for 3, 6, 10, and 20 days; from chicks treated with hormone for 10 days and then withdrawn for 2 days; and from mature hens were incubate... | [
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0.0251683... |
10,001,683 | Ribosomal protein synthesis during spore germination and vegetative growth in Dictyostelium discoideum. | [
0.02069093845784664,
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0.04181014373898506,
0.020608... |
10,001,684 | We have investigated the regulation of the synthesis of each ribosomal protein during spore germination and in vegetatively growing cells of Dictyostelium discoideum. Germinating spores and exponentially growing amoebae were labeled with [35S]methionine and the individual ribosomal proteins were resolved by electrophor... | [
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0.07328640669584274,
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0.06946992874145508,
0.0506664... |
10,001,685 | Purification and ATP substrate site of a cyclic nucleotide-independent protein kinase (NI) from porcine liver nuclei. | [
-0.04633791372179985,
0.04549557343125343,
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0.007366035133600235,
0.01... |
10,001,686 | Synthesis and inactivation of bacterial luciferase determined by immunochemical techniques. Comparison with total protein synthesis and turnover. | [
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0.005204270128160715,
0.08200... |
10,001,687 | Podophyllotoxin-resistant mutants of Chinese hamster ovary cells. Alteration in a microtubule-associated protein. | [
-0.00006302318070083857,
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0.02534235082566738,
0.008994052186608315,
0.021612688899040222,
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-... |
10,001,688 | Characterization of a human intestinal difucosyl heptaglycosylceramide with a blood group B determinant and a type 1 carbohydrate chain. | [
0.04197407886385918,
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0.03132391348481178,
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0.... |
10,001,689 | Kinetics and mechanism of carbon monoxide binding to purified liver microsomal cytochrome P-450 isozymes. | [
0.01841343753039837,
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0.04... |
10,001,690 | Haloenol lactones: enzyme-activated irreversible inactivators for serine proteases. Inactivation of alpha-chymotrypsin. | [
0.04553480073809624,
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0.06834352... |
10,001,691 | Two haloenol lactones have been shown to inactivate alpha-chymotrypsin by an enzyme-mediated process. According to the postulated mechanism, acylation of the active site serine by the haloenol lactone reveals an alpha-haloketone, which alkylates the enzyme at the active site and renders the enzyme inactive. The inactiv... | [
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0.0025107059627771378,
-0.06598004698753357,
0.0480... |
10,001,692 | Inhibition of chemotaxis by S-3-deazaadenosylhomocysteine in a mouse macrophage cell line. | [
-0.07535496354103088,
-0.06586813181638718,
-0.1098015233874321,
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0.07661456614732742,
0.016422... |
10,001,693 | Chemotaxis by a macrophage cell line, RAW264, is specifically inhibited by the intracellular accumulation of 3-deazaadenosylhomocysteine (3-deaza-AdoHcy). Intracellular accumulation of 3-deaza-AdoHcy is the result of incubation of the cells with 3-deazaadenosine, a compound that can function both as a substrate and as ... | [
-0.09153340011835098,
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0.004246102180331945,
0.05045442655682564,
0.01... |
10,001,694 | Amino acid sequences of the epsilon and alpha E globins of HbE, a minor early embryonic hemoglobin of the chicken. | [
-0.019301429390907288,
-0.049502141773700714,
-0.06858596205711365,
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0.005161851644515991,
0.04950816184282303,
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-0.07591747492551804,
0.0... |
10,001,695 | We have determined amino acid sequences for the alpha-like and beta-like globin components of HbE, one of the two minor hemoglobins in early chick embryos. The complete primary structure of the epsilon chain differs at 18 positions from the adult chicken beta globin, but there are no changes in heme-binding residues, a... | [
-0.0418870784342289,
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-0.03865163028240204,
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0.00988083891570568,
0.03442292660474777,
0.030083606019616127,
-0.06616095453500748,
0.047495... |
10,001,696 | Minor early embryonic chick hemoglobin M. Amino acid sequences of the epsilon and alpha D chains. | [
-0.05182900279760361,
-0.09310467541217804,
-0.024239100515842438,
-0.05746889486908913,
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0.03494434058666229,
0.04491310939192772,
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0.03955802693963051,
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0.04096612706780434,
-0.059107836335897446,
0.041... |
10,001,697 | Erythrocytes of the early chick embryo contain four hemoglobins, two major and two minor. In this paper, we present amino acid sequences for the beta-like and alpha-like chains of HbM, the least abundant of the four early chick hemoglobins. The complete amino acid sequence of the beta-like chain of HbM is identical wit... | [
-0.04067089408636093,
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0.015237593092024326,
0.0012375513324514031,
0.06551148742437363,
-0.0982452780008316,
-0.0011... |
10,001,698 | Clofibric acid and phenylpyruvic acid as biochemical probes for studying soluble bovine liver branched chain ketoacid dehydrogenase. | [
-0.009346586652100086,
-0.08503518998622894,
-0.04512932896614075,
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0.008221122436225414,
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-0.020608924329280853,
0.0320... |
10,001,699 | Purified bovine liver branched chain ketoacid dehydrogenase is inhibited by its reaction products, NADH and the branched chain acyl-CoA thiol esters. This provides an immediate, short term regulation mechanism for this enzyme which commits leucine, isoleucine, and valine to the catabolic pathway. We find that clofibric... | [
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0.029070936143398285,
-0.0015396290691569448,
-0.05776386335492134,
0.016536744311451912,
0.0... |
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