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10,005,100 | Selection for insecticide resistance in the Australian sheep blowfly, Lucilia cuprina. | [
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10,005,101 | Egg implant studies on sheep demonstrate that the relative fitness of resistance genotypes of the sheep blowfly, Lucilia cuprina, changes over time for the 2 insecticides dieldrin and diazinon. The results suggest that selection may occur following exposure of larvae to sub-lethal concentrations and help to explain the... | [
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10,005,102 | RNA polymerase activities in the isolated perfused rat liver. | [
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10,005,103 | Precipitate formation of some sulfonated tetrazolthiomethyl cephalosporins with basic chemicals. | [
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10,005,104 | Cephalosporins containing a thiomethyltetrazole-sulfomethyl or sulfoaminoethyl substituent at the three-position react in aqueous solution with protamine or quinine to form a precipitate. This phenomenon may provide some insight into their pharmacokinetics and modes of action especially as it relates to the high and pr... | [
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10,005,105 | Cell cycle patterns of thymidylate synthetase and 5,10-methylenetetrahydrofolate polyglutamates in cultured mouse hepatoma cells. | [
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10,005,106 | The regulation of thymidylate synthetase activity was investigated throughout the first cell cycle after release from an isoleucine block in synchronous cultures of mouse hepatoma (Hepa) cells. Activity in cell extracts increased with the onset of S phase and the increased activity was attributed to a parallel increase... | [
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10,005,107 | Alterations of plasma lipoproteins and hepatic lipid biosynthesis in FV3-induced hepatitis in mice. | [
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10,005,108 | Comments on effect of thrombocytopenia on wound healing: a study in the rat. | [
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10,005,109 | Ultrastructural studies of coronary arterial intima. I. Intimal cell nest and serofibrinous insudation in 6-month-old swine. | [
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10,005,110 | Recovery from ozone-induced injury in the lungs of the Syrian golden hamster. | [
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10,005,111 | Acute effects of selected hepatotoxic agents on polyribosomes and protein synthesis in the livers of rats fed purified diets containing hepatocarcinogens. | [
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10,005,112 | Pharmacokinetics of deslanoside C-3H administered orally to healthy volunteers. | [
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10,005,113 | Radiopaque contrast media. XLVII - Determination of the optical purity of iopamidol. | [
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10,005,114 | Determination of vitamin C in tablets and fruits by titration with phenyliodosoacetate. | [
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10,005,115 | [Search for agents with prolonged anesthetizing action (the neurolytic type of local anesthetizing action)]. | [
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10,005,116 | Compounds that possess long-term anesthetic effect have been found among phenylethylamine derivatives substituted by O-alkyl (position 4) or O-benzyl (positions 2, 3 and 4) radicals. It was shown that these compounds compare very favourably with novocain, since their anesthetic effect exceeds 54.8 - 66.9-fold that prod... | [
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10,005,117 | [Effect of hormones on lipid peroxidation in the heart and liver]. | [
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10,005,118 | In the course of a comparative study of lipid peroxidation in the heart and liver it was disclosed that this process in the rat heart proceeds less intensely than in the liver, which may be a consequence of the different levels of non-protein thiols in the test organs. Study of the effect of estradiol, thyroxine, hydro... | [
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10,005,119 | [Effect of armin and dipyroxime on the nicotinamide coenzyme and adenine nucleotide content of the rat myocardium and liver]. | [
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10,005,120 | It has been shown in rat experiments that armin in doses that inhibit blood cholinesterase by 50 and more per cent lowers the content of nicotinamide coenzymes in the myocardium and liver of the animals, primarily at the expense of the diminution of the oxidized forms. In the rat liver, armin decreases the content of a... | [
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10,005,121 | [Effect of strophanthin and celanide on the tonus of the cerebral and peripheral vessels]. | [
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10,005,122 | Resistography was used in acute experiments on anesthetized cats to demonstrate that cardiac glycosides, particularly celanide, often cause phasic (constrictive-dilative) responses of the perfused vessels and general arterial pressure. The constrictive response of the perfused vessels did not depend on the concentratio... | [
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10,005,123 | [Effect of vasodilator agents on the electrolyte balance and the transmural potential difference in the wall of blood vessels]. | [
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10,005,124 | It has been shown in experiments on adult cats that chronic treatment of normotensive animals with vasodilators leads to inconsistent changes in the transmural potential difference and electrolyte balance of the wall of blood vessels. A permanent correlation has been revealed to exist between vasodilation and increased... | [
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10,005,125 | [Inhibition of free-radical lipid peroxidation in myocardial infarct as affected by strophanthin]. | [
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10,005,126 | It was shown in experiments on rats with experimental ischemic myocardial infarction that strophanthin inhibits free-radical lipid peroxidation, decreases (in mean and little doses) the ectopic activity of the myocardium, eliminates tachyarrhythmias arising in the presence of coronary occlusion, delays the appearance o... | [
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10,005,127 | [Effect of the new antidepressant cephedrine on compensatory hypertrophy of the ovaries and the inhibiting effect of estrogen]. | [
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10,005,128 | It has been shown in experiments on female albino rats that cephedrine in doses of 20 and 50 mg/kg (per os) prevents the inhibitory action of diethylstilbestrol propionate on compensatory hypertrophy of the ovary. It has been demonstrated that on being given in a dose of 50 mg/kg the drug itself favours more pronounced... | [
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10,005,129 | [Changes in the enzyme activity of the hydroxylating system of the rat liver endoplasmic reticulum in ischemia]. | [
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10,005,130 | Local disturbance of liver circulation for 40 minutes did not lead to any substantial changes in the hydroxylation system of microsomes of the ischemized area. 60-, 120- and 180-minute circulation distress causes a progressing decrease in amidopyrine and aniline metabolism, diminution of the content of cytochrome P-450... | [
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10,005,131 | [Dioxidine and carbenicillin in Pseudomonas aeruginosa pyelonephritis in rats]. | [
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10,005,132 | Dioxidine (50 mg/kg a day) and carbenicillin (500 mg/kg a day) administered to rats with Ps. aeruginosa hematogenic pyelonephritis for 7 days brought about high therapeutic effect accompanied by bacteremia elimination, noticeable reduction of bacteriuria and dissemination of renal tissue, by improvement of the histolog... | [
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10,005,133 | [Effect of pharmacological agents on the development of hemic hypoxia]. | [
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10,005,134 | The quantitative structure-activity relationship of rifamycin B amide and hydrazide toxicity in mice. | [
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10,005,135 | Quantitative structure-activity relationships (QSAR) are developed for the acute toxicity of a number of rifamycin B amides and hydrazides in mice. The equations indicate a parabolic dependence of toxicity on the partition coefficient. Two related compounds, rifamycin SV and rifamycin B, were included with the amides i... | [
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10,005,136 | Derivatives of 5,7,7-trimethyl-6-oxa-3-azabicyclo[3.2.2.] nonane with antiarrhythmic, local anesthetic and hypotensive activities. III. | [
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10,005,137 | The synthesis of alkyl and aryl ureas (II) derived from 5,7,7-trimethyl-6-oxa-3-azabicyclo[3.2.2.]nonane (I), as well as hydrazides (V), (VI) and (VII) derived from 5,7,7-trimethyl-6-oxa-3-azabicyclo[3.2.2]-nonan-3-amine (IV), is described. A number of theses compounds showed strong hypotensive and bradycardic activiti... | [
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10,005,138 | [Teratogenic and embryotoxic properties of drugs and alcohol]. | [
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10,005,139 | Experiments on rats were made to study the direct and mediated action of a number of drugs (antibiotics, drugs of the phenothiazine series, prostaglandin F2alpha , partusisten, staphylococcal anatoxin) and alcohol on the development of the fetoplacental complex. The author emphasizes the necessity of a comprehensive ap... | [
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10,005,140 | Synthesis and pharmacological activity of derivatives of exo-trimethylenenorbornane, IV. | [
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10,005,141 | The syntheses of (+/-)-1-(exo-5,6-trimethylenenorbornan--2-yl)2-propanamine (IV) starting from (exo-5-trimethylenenobornan-2-yl)acetic acid (I) or (exo-5,6-trimethylenenorbornan-2-yl)acetonitrile (II), as well as a series of amides (V) described. None of compounds (IV) and (V) showed amphetamine-like activity in mice. | [
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10,005,142 | [Time periods for the realization of the embryotoxic action of cyclophosphamide and chloridin in vivo and in vitro]. | [
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10,005,143 | Female rats with 10-day pregnancy were given cyclophosphamide (30 mg/kg) or chloridin (25 mg/kg). Following 15 minutes - 24 hours the embryos were explanted into the cultural medium containing no teratogenic agents indicated. It has been shown that pathological processes in the embryos became irreversible 15 - 30 minut... | [
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10,005,144 | [Effect of anabasine hydrochloride on embryogenesis in white rats and rabbits]. | [
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10,005,145 | The author reports the results of testing the embryotropic activity of anabasineee hydrochloride in doses of 15, 5, and 3 mg/kg. It was found that oral administration of the drug to pregnant rats in doses exceeding 10-fold (5 mg/kg) and 20-fold (10 mg/kg) the therapeutic ones produced no adverse effect on the fetus. In... | [
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10,005,146 | Correction for the metabolic exchange of 14C for 12C atoms in the pathway of gluconeogenesis in vivo. | [
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10,005,147 | Methods designed for estimation of the synthesis of plasma glucose are based on the transfer of 14C atoms from a selected precursor (substrate) such as lactate or alanine. This approach was shown to lead to an underestimation of the true synthesis of glucose because of the metabolic exchange of 14C atoms for 12C atoms ... | [
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10,005,148 | Gluconeogenesis in the ruminant fetus: evaluation of conflicting evidence from radiotracer and other experimental techniques. | [
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10,005,149 | Conflicting evidence exists as to whether the gluconeogenetic process is active in the late gestation fetal lamb. In vitro evidence based on measurements of enzyme activity and substrate flux into glucose indicates that the capacity for gluconeogenesis exists in fetal liver. The in vivo conversion of [14C]lactate and [... | [
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10,005,150 | [Protective action of sodium succinate in ethionamide poisoning]. | [
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10,005,151 | Importance of sites of tracer administration and sampling in turnover studies. | [
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10,005,152 | [Characteristics of drug interaction with staphylococcal toxin]. | [
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10,005,153 | UV spectra of ethazole, streptomycin, monomycin and penicillin in different concentrations were studied separately and in combination with staphylococcal toxin. The drugs under study interact with staphylococcal toxin to form biocomplexes depending on their concentration in the reaction mixture. The biocomplexes drug-t... | [
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10,005,154 | Stress-strain analysis and the lung. | [
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... |
10,005,155 | Stress is the magnitude and direction of forces acting on a body, and strain is the magnitude and direction of deformations. Constitutive equations define the relationship between stress and strain for any material. If the material can be considered homogeneous, isotropic, and elastic--that is, if the mechanical proper... | [
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10,005,156 | Fluorescent membrane probes and the mechanism of maintenance of cellular asymmetry in epithelia. | [
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10,005,157 | Individual epithelial cells are asymmetric with respect to morphology, distribution of enzymes, lipid composition, ionic permeability, and sensitivity to drugs and hormones on the apical (mucosal) versus basolateral (serosal) membranes. It has been suggested that the tight junction, which forms the morphological bounda... | [
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10,005,158 | Alternative methods for measurement of membrane potentials in epithelia. | [
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10,005,159 | Methods for the measurement of membrane potentials in cells not easily penetrated by microelectrodes were assessed for use in epithelia. The lipophilic cation triphenylmethylphosphonium appeared to distribute in a Nernstian fashion in the epithelial cells of Necturus gallbladder as judged by parallel microelectrode mea... | [
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10,005,160 | Intestinal calcium transport: pleiotropic effects mediated by vitamin D. | [
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10,005,161 | The primary biological response to vitamin D is an increase in intestinal calcium transport. Efforts to elucidate the molecular mechanism by which this increased transport occurs has revealed that vitamin D mediates pleiotropic effects that are most likely a result of both genomic and nongenomic mechanisms of action of... | [
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10,005,162 | Isolation of the protein IMCal, a vitamin D-dependent membrane component of the intestinal transport mechanism for calcium. | [
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10,005,163 | Regulation of the intestinal absorption of calcium by vitamin D in the rat involves the synthesis or maintenance of specific membrane proteins. A particulate preparation derived from duodenal mucosal homogenates or isolated microvillus membranes contains at least three vitamin D-dependent activities: calcium binding, p... | [
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10,005,164 | Pathways of carbon flux in gluconeogenesis. | [
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10,005,165 | Although the classical pathways of gluconeogenesis are now well understood, they alone do not account for the rate of incorporation of isotopes from labeled precursors into glucose or for the distribution of isotopes within the glucose molecule. Additional factors include the rate of glycerol metabolism relative to the... | [
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10,005,166 | Federation of American Societies for Experimental Biology. 66th annual meeting. New Orleans, Louisiana, April 15-23, 1982. Abstracts of papers 1-3477. | [
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10,005,167 | Mathematical model for the distribution of isotopic carbon atoms through the tricarboxylic acid cycle. | [
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10,005,168 | Federation of American Societies for Experimental Biology. 66th Annual meeting. New Orleans, Louisiana, April 15-23, 1982. Abstracts of papers 3478-6993. | [
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10,005,169 | [Effect of partial denervation of the ovaries on their sensitivity to adrenal cortex hormones after manipulating the amygdaloid nucleus]. | [
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10,005,170 | [Non-adrenergic inhibition of small intestine motility]. | [
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0.06542... |
10,005,171 | [Use of plant and vitamin preparations to prevent stomach ulcers induced by immobilization, noise and vibration in rats]. | [
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10,005,172 | [Stimulation of antibody formation in the spleens of rats exposed to an alternating magnetic field in the thoracic region]. | [
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0.0938... |
10,005,173 | [Serotonin and histamine liberation in experimental skin wounds]. | [
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0.062390513718128204,
0.046753376722335815,
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0.043142858892679214,
-0.03783954679965973,
0.005300168879330158,
-0.04669712856411934,
0.12484... |
10,005,174 | [Effect of damage to the superior cervical sympathetic ganglion in rabbits on microcirculation and catecholamine concentration in tissues of mucous membranes innervated by it]. | [
0.09547532349824905,
-0.09603676944971085,
0.05896371230483055,
0.04214704409241676,
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0.08171145617961884,
0.0377078652381897,
0.010637249797582626,
0.0030290032736957073,
0.08193... |
10,005,175 | [Phasic nature of responses of the pituitary-adrenal system at high altitudes]. | [
0.028080428019165993,
0.023568009957671165,
0.01632516086101532,
0.03668162226676941,
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0.032754234969615936,
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0.013632568530738354,
0.02110968343913555,
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-0.04619269445538521,
0.026... |
10,005,176 | [Significance of fibrosis in liver pathology]. | [
0.04489540681242943,
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-0.06529105454683304,
-0.015916474163532257,
0.0010082466760650277,
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0.044134799391031265,
0.034702103585004807,
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0.0... |
10,005,177 | [Age and changes in thyroid function and tissue metabolism of its hormones]. | [
0.04978536069393158,
0.03171444684267044,
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0.053995583206415176,
0.006926328409463167,
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-0... |
10,005,178 | [Morphologic changes in the hematopoietic organs of rats in response to adrenaline]. | [
0.11482896655797958,
0.020824121311306953,
0.024401189759373665,
0.05394363030791283,
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0.002633... |
10,005,179 | [Analysis of the effect of isoprenaline on skeletal muscle energy consumption]. | [
0.03354387730360031,
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0.056845396757125854,
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0.01972831040620804,
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10,005,180 | [Effect of small rectilinear sign-variable accelerations on the state of the intestinal mucosa in dogs]. | [
0.039302803575992584,
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0.007048902101814747,
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0.07720080018043518,
0.101761... |
10,005,181 | [Effect of cooling on the state of various glycolytic and tricarboxylic acid cycle enzymes in intact and denervated skeletal muscles in rats]. | [
-0.02391676791012287,
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0.027... |
10,005,182 | [Dynamics of changes in transmural potential difference during ischemia of the small intestine]. | [
0.06428825110197067,
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0.07... |
10,005,183 | [Effect of cold on catecholamine fluorescence in various rat brain structures]. | [
0.03127147629857063,
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0.02870543673634529,
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0.014... |
10,005,184 | [Effect of therapeutic enzyme preparations on submaxillary gland enzyme activity in rats with experimental traumatic submaxillitis]. | [
0.054108548909425735,
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0.004626161884516478,
0.02665872685611248,
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0.188... |
10,005,185 | The effect of chemical and physiological factors on the kinetics for product formation as it relates to enzyme activity and concentration, reaction time and to substrate adsorption and affinity. | [
0.009541066363453865,
-0.11746853590011597,
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0.04640156030654907,
0.0065916855819523335,
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10,005,186 | 1. The dependency of product formation on reaction time and on enzyme concentration was studied with certain purified enzymes and liver microsomal mixed-function oxidase system. 2. The product-formation-time relation was estimated with different enzyme and/or substrate concentrations for the reactions limited by diffus... | [
0.05633854493498802,
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0.01343995425850153,
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0.04749532416462898,
0.02246970310807228,
0.04435217007994652,
0.0154294... |
10,005,187 | [Oxidative phosphorylation in the mitochondria of tissues of newborn calves]. | [
-0.011085555888712406,
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0.07112646847963333,
0.015061837621033192,
0.015920467... |
10,005,188 | Cooperative ATP inhibition and fructose-1,6-biphosphate activation of rat liver pyruvate kinase. | [
-0.0011567143956199288,
0.04411017522215843,
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0.017793534323573112,
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0.00... |
10,005,189 | Cholesterol metabolism in cancer cells in monolayer culture--IV. regulation of cholesteryl ester synthesis. | [
-0.03669361025094986,
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-0.01110583171248436,
-0.028217485174536705,... |
10,005,190 | [Changes in catecholamine excretion in adolescents at high altitudes]. | [
0.051375940442085266,
0.01929605007171631,
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0.021190375089645386,
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... |
10,005,191 | Development and kinetic aspects of rat eye aldehyde dehydrogenase. | [
0.004390298388898373,
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0.06944479793310165,
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... |
10,005,192 | Relations between size, secondary structure content and amino acid composition in globular proteins. | [
-0.01575448550283909,
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-0.018052922561764717,
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0.015221870504319668,
0.005346026737242937,
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0.0... |
10,005,193 | 1. A statistical analysis of the relations between the size, helical, B-strand content and amino acid composition on 27 globular proteins has been undertaken. 2. The helical content was correlated with composition of helix-forming and inversely with that of helix-breaking amino acids, though the degree of correlation w... | [
-0.006450072396546602,
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0.04152238741517067,
0.02954600192606449,
0.044020771980285645,
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0.06... |
10,005,194 | [Response of microstructures of the subcommissural organ to changes in the lighting schedule]. | [
0.045321669429540634,
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0.10630916804075241,
0.056858666241168976,
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0.06563115864992142,
0.007336688693612814,
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-0.03837929293513298,
0.0... |
10,005,195 | [Effect of potassium on the rate of aldosterone secretion in old and young rats]. | [
0.007553027011454105,
0.009521666914224625,
0.002636411925777793,
0.04270349442958832,
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0.021258311346173286,
0.021197903901338577,
0.032349638640880585,
0.020990025252103806,
0.019... |
10,005,196 | Defective activation of androgen-receptor complexes: a marker of androgen insensitivity. | [
-0.045366235077381134,
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0.0794604942202568,
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0.03957938402891159,
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-0.001829019864089787,
... |
10,005,197 | Partially-purified 5 alpha-dihydrotestosterone-receptor (DHT-R) complexes, extracted from normal genital skin fibrolasts (GSF) previously labelled with [3H]DHT, dissociate with monophasic kinetics and dissociation rate constants (k-2) of 10, 6, 3 and 2 x 10(-3) min-1 at 40, 37, 32 and 29 degrees C, respectively. An Arr... | [
-0.006949085276573896,
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0.04448449984192848,
0.04242571443319321,
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0.07462175190448761,
0.00996874924749136,
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-0.09499441087245941,
0.079... |
10,005,198 | Cytosol and nuclear progesterone-receptor concentrations in the rabbit endometrium during early pseudopregnancy under different treatments with estradiol and progesterone. | [
0.03179634362459183,
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0.006283831782639027,
0.061122067272663116,
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0.09979098290205002,
0.03925158455967903,
0.04831322655081749,
-0.02276952564716339,
0.05690450... |
10,005,199 | In an attempt to understand the mechanism of the antiprogestational action of estrogens during early pseudopregnancy we determined the cytosolic and nuclear concentrations of progesterone receptors in the endometrium of rabbits treated with hCG followed by various combinations of estradiol and progesterone. The progest... | [
0.01103555504232645,
-0.07950783520936966,
-0.0290242750197649,
0.08603977411985397,
0.0016805768245831132,
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0.03083140403032303,
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0.10661638528108597,
-0.0019042470958083868,
0.004068319220095873,
-0.044629551470279694,
0.01487... |
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