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10,006,701 | Self-perceived personality change in adulthood and aging. | [
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10,006,702 | This study replicated and extended a previous work on self-perceived personality change in the middle- to old-age transition. A modified form of the Rokeach Value Survey (previously administered to women) was given to 80 middle-aged and 80 old-aged men and women. Self-perceived change was examined by varying instructio... | [
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10,006,703 | Sex, sex guilt, and contraceptive use. | [
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10,006,704 | The Mosher True-False Sex-Guilt Inventory and questionnaires about sexual activity and contraceptive use were administered to a sample of 109 female college students in 1973 and a comparable sample of 111 female college students in 1978. Comparisons of these samples revealed an increase in sexual activity and a decreas... | [
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10,006,705 | Images of violence in Thematic Apperception Test stories. | [
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10,006,706 | Hardiness and health: a prospective study. | [
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10,006,707 | Unique and common variance in structured interview and Jenkins Activity Survey measures of the type A behavior pattern. | [
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10,006,708 | The aim of the present study was to identify factors that account for similarities and discrepancies in classification of Type A and B behavior by the Structured Interview (SI) and by the Jenkins Activity Survey (JAS). Two diverse samples were administered the SI and the JAS. SI questions were coded for content of resp... | [
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10,006,709 | On the self-serving function of an academic wooden leg: test anxiety as a self-handicapping strategy. | [
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10,006,710 | The present study investigated the hypothesis that psychological symptoms may serve a self-protective function by providing an alternative explanation for potential failure in evaluating situations. It was hypothesized that highly test-anxious subjects would report anxiety symptoms in a pattern that reflected strategic... | [
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10,006,711 | Origins of health locus of control beliefs. | [
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10,006,712 | A burgeoning literature is discovering the links between locus of control beliefs and a variety of different health beliefs, health behaviors, and health itself. If locus of control beliefs are important to health, it is crucial to understand where those beliefs come from. This study explored the origins of health locu... | [
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10,006,713 | Depression and self-reinforcement in a public and a private setting. | [
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10,006,714 | Three groups of subjects--depressed, nondepressed, and nondepressed pretreated with an insolvable-problems (failure) manipulation--were compared on self-reinforcement during a 22-trial skill task. Success rate was experimentally controlled, and all subjects received either an initially high rate of success followed by ... | [
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10,006,715 | Liposome disposition in vivo II: Dose dependency. | [
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10,006,716 | The dose-dependent disposition of extruded multilamellar (diameter approximately 1 micrometer) negatively charged liposomes containing entrapped [14C]inulin was studied in mice. Mice received 1500, 300, or 15 mumoles of liposomal lipid/kg iv. Carbon 14 levels were measured in the blood, liver, spleen, and carcass for ... | [
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10,006,717 | Phase equilibria of nafcillin sodium-water. | [
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10,006,718 | The phase diagram for the binary system nafcillin sodium-water, was determined using differential scanning calorimetry (DSC) and polarized light microscopy. In the temperature range of -20-30 degrees, three crystalline forms and an amphiphilic liquid crystalline phase were detected. The stable crystalline form of nafci... | [
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10,006,719 | GLC determination of bromperidol in tablets. | [
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10,006,720 | High-performance liquid chromatographic determination of metoprolol in plasma. | [
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10,006,721 | A high-performance liquid chromatographic method is presented for the determination of metoprolol in human plasma. Metoprolol was extracted from plasma by a single extraction procedure with 4-methylpropranolol as the internal standard. Chromatography was done on a reversed-phase column with fluorescence detection. The ... | [
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10,006,722 | Stability of phenylpropanolamine hydrochloride in liquid formulations containing sugars. | [
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10,006,723 | Stability studies with a decongestant syrup formulation containing phenylpropanolamine hydrochloride in a sugar vehicle indicated a loss of phenylpropanolamine hydrochloride. To ascertain the biological significance of this indicated chemical loss, the degraded formulation was administered to human volunteers and the u... | [
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10,006,724 | Synthesis of 7,7-diaryl-4,5,7,-tetrahydroimidazo-[4,5-c]pyridines. | [
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10,006,725 | Quality control of phenylbutazone II: Analysis of phenylbutazone and its decomposition products in drugs by high-pressure liquid chromatography. | [
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10,006,726 | A rapid, sensitive, accurate, and reproducible procedure for the simultaneous separation and determination of phenylbutazone and three major degradation products is proposed using reversed-phase high-pressure liquid chromatography and UV detection. The method is approximately 20 times more sensitive than TLC and allows... | [
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10,006,727 | Active conformation of polycyclic antidepressants. | [
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10,006,728 | Potential errors in determining Freundlich and Langmuir constants from adsorption isotherms. | [
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10,006,729 | 1-Aryl-3,3-dialkyltriazenes with antitrypanosomal activity. | [
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10,006,730 | Stability of heparin and other fractions of glycosaminoglycan sulfates in human digestive juices. | [
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10,006,732 | Adsorption of methotrexate onto glassware and syringes. | [
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10,006,733 | Pharmacokinetic and biopharmaceutic parameters during enterohepatic circulation of drugs. | [
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10,006,734 | Predictions of stability in pharmaceutical preparations XIX: Stability evaluation and bioanalysis of clofibric acid esters by high-pressure liquid chromatography. | [
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10,006,735 | Specific, sensitive, reversed-phase high-pressure liquid chromatographic assays of clofibric acid esters, clofibrate and etofibrate, and their hydrolysis products, clofibric acid and its monoglycolate and nicotinic acid and its monoglycolate, have been developed in aqueous solution and in biological fluids. Sensitiviti... | [
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10,006,736 | Pharmacokinetic interactions of tolazamide and oxyphenbutazone in dogs. | [
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10,006,737 | The described pharmacokinetic analysis involved two separate studies on nine dogs randomly assigned to three groups of three dogs each. In the first study, the effect of varying the dosage of tolazamide was examined. The second study concerned the effect of varying the dosage of oxyphenbutazone on tolazamide. A 3 x 3 L... | [
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10,006,738 | Influence of food and fluid volume on chlorothiazide bioavailability: comparison of plasma and urinary excretion methods. | [
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10,006,739 | The bioavailability of chlorothiazide from oral tablets was examined under fasting and nonfasting conditions in healthy male volunteers. Bioavailability was determined from urinary excretion data and plasma chlorothiazide concentrations. Two fasting treatments and one nonfasting treatment yielded similar plasma chlorot... | [
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0.078... |
10,006,740 | Tray drying of pharmaceutical wet granulations. | [
-0.019490715116262436,
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0.0... |
10,006,741 | It is shown that in tray drying wet granulated materials, the expected log-linear plots give slopes that are inversely proportional to the bed depth, rather than to the depth squared. A model is proposed for this giving diffusion coefficients of the order of magnitude expected fro liquid-water diffusion. The temperatur... | [
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0.0940... |
10,006,742 | Quantitation of methadone enantiomers in humans using stable isotope-labeled [2H3]-, [2H5]-, and [2H8]Methadone. | [
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0... |
10,006,743 | A new technique for simultaneous stereoselective kinetic studies of methadone enantiomers was developed using three deuterium-labeled forms of methadone and GLC-chemical-ionization mass spectrometry. A racemic mixture (1:1) of (R)-(-)-[2H5]methadone (l-form) and (S)-(R)-[2H3]methadone (d-form) was administered orally i... | [
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... |
10,006,744 | Effect of surface charge and particle size on gel structure of aluminum hydroxycarbonate gel. | [
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0.02... |
10,006,745 | The effect of surface charge and particle size on the gel structure of aluminum hydroxycarbonate gel was studied through the use of a specially designed tension cell. Surface charge has a major effect on the coefficient of bulk compressibility. The charged state is more compressible at lower tensions while the neutral ... | [
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0... |
10,006,746 | Comparison of effects of cyanide and acetylcholine on renal hemodynamics and sodium excretion. | [
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10,006,747 | The present study compared the effects of acetylcholine to cyanide under the same experimental conditions of renal clearance in anesthetized dogs. Since cyanide is one of the few drugs for which the mechanism of action is known (cytotoxic hypoxia), some insight may be gained into the renal effects of acetylcholine sinc... | [
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0.05... |
10,006,748 | Kinetics of chlorambucil hydrolysis using high-pressure liquid chromatography. | [
-0.00015778854140080512,
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0.02... |
10,006,749 | A stability-specific high-pressure liquid chromatographic (HPLC) method was developed to assay intact chlorambucil (I) in the presence of its hydrolytic decomposition products. The HPLC method was used to follow the degradation kinetics of I over pH 1.0-10.0 in the presence of various buffers with and without added chl... | [
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0.040169... |
10,006,750 | Preparation and screening of some new thioacetals, sulfones, and derivatives of 4-dichloromethylbenzoyl and 4-trichloromethylbenzoyl chloride as potential antimalarials. | [
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0.0... |
10,006,751 | The preparation and screening of some potential antimalarials are reported. The new compounds which are inactive as antimalarials are several benzene-, benzyl-, and fluorene thioacetals, beta-disulfones derived from these thioacetals, alpha-chlorobenzyl sulfones, amides, and thioesters derived from 4-dichloromethylbenz... | [
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10,006,752 | GLC analysis of trifluoperazine in human plasma. | [
-0.0028234857600182295,
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0.10... |
10,006,753 | This report describes a sensitive gas chromatographic procedure for the measurement of trifluoperazine in human plasma. Trifluoperazine was extracted into heptane-2-propanol by a two-step procedure and analyzed directly without derivatization. Prochlorperazine was employed as an internal standard because its structural... | [
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0.098... |
10,006,754 | Contribution of lungs to total body clearance: linear and nonlinear effects. | [
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0.05... |
10,006,755 | The contribution of the lungs to the total body clearance of drugs is examined in a framework that emphasizes their anatomical position. For intravenous administration, the lung is the only organ other than blood that can account for a total body clearance in excess of the cardiac output. Systemic arterial drug concent... | [
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0.079... |
10,006,756 | Quantitative evaluation of pharmaceutical effervescent systems II: Stability monitoring by reactivity and porosity measurements. | [
0.04232558608055115,
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0.0098... |
10,006,757 | The stability of selected effervescent tablet systems was monitored by means of mercury intrusion porosimetry and by a cantilever beam/proximity transducer balance. The porosity measurements proved to be useful in elucidating tablet pore structure changes over time. The measured parameter, percent pores greater than th... | [
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... |
10,006,758 | Comparison of serum bilirubin levels in humans and two monogastric animal species after a single administration of sulfisoxazole. | [
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0.11253... |
10,006,759 | Administration of sulfonamides during periods of hepatobiliary failure or hepatic immaturity increases the toxic potential of unconjugated or indirect bilirubin. A small but statistically significant increase of indirect, or unconjugated bilirubin was noted in dogs after oral administration of sulfisoxazole (100 mg/kg)... | [
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0.133570998907... |
10,006,760 | Reversed-phase high-pressure liquid chromatographic determination of serum methotrexate and 7-hydroxymethotrexate. | [
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-0.018... |
10,006,761 | A reversed-phase high-pressure liquid chromatographic method for determining methotrexate and 7-hydroxymethotrexate in human serum is presented. A mobile phase of acetate buffer (0.2 M, pH 5.5 with 0.03 M ethylenediaminetetraacetate), methanol, and acetonitrile (85.3:8.4:6.3), passed through a mu Bondapak C18 column at... | [
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0.02208... |
10,006,762 | Theoretical and experimental studies of transport of micelle-solubilized solutes. | [
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0.02865... |
10,006,763 | A physical model describing the simultaneous diffusion of free solute and micelle-solubilized solute across the aqueous boundary layer, coupled with partitioning and diffusion of free solute through a lipoidal membrane, is derived. In vitro experiments utilizing progesterone and polysorbate 80 showed excellent agreemen... | [
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0.03... |
10,006,764 | High-performance liquid chromatographic determination of suprofen in drug substance and capsules. | [
0.005185657646507025,
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0.00319159054197371,
0.07497754693031311,
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0.0300749111... |
10,006,765 | A rapid, simple, stability-indicating assay procedure for suprofen, a new analgesic agent, in suprofen drug substance and in capsules was developed using high-performance liquid chromatography. Suprofen was extracted from the sample matrix with methanol and diluted with internal standard solution, and an aliquot was ch... | [
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0.0427420... |
10,006,766 | Measurements of ionization constants and partition coefficients of quanazole prodrugs. | [
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0.0575309619307518,
0.1129762... |
10,006,767 | A series of guanazole prodrugs, which are less water soluble than the parent compound and have relatively higher molecular weights, was recently synthesized, and their antineoplastic activities were measured in vitro. In present work, the ionization constants and partition coefficients of these compounds were measured ... | [
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0.03482986241579056,
0.0222... |
10,006,768 | Buprenorphine effects on plasma luteinizing hormone and prolactin in male heroin addicts. | [
0.04202916473150253,
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0.0851626917719841,
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0.0583039857... |
10,006,769 | Buprenorphine, a mixed opiate agonist-antagonist, suppressed plasma luteinizing hormone (LH) and increased prolactin levels after 12 consecutive days of ascending dose administration (0.5-8 mg/day s.c.) in comparison to drug-free control conditions. During a subsequent 10-day period of buprenorphine maintenance at a do... | [
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0.007289429660886526,
0.058688... |
10,006,770 | Human cigarette smoking: manipulation of number of puffs per bout, interbout interval and nicotine dose. | [
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0.02051975391805172,
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-0.0356... |
10,006,771 | In a residential research ward, cigarette smoking was studied during 12-hr daily sessions in seven volunteer human subjects with histories of regular smoking. Puff-to-puff delivery of cigarette smoke was held relatively constant by instructing and monitoring subjects in taking uniform puffs and by specifying and timing... | [
0.03407617658376694,
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0.02... |
10,006,772 | The effects of serotonin antagonists on the inhibition of primate spinothalamic tract cells produced by stimulation in nucleus raphe magnus or periaqueductal gray. | [
0.0350368395447731,
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0.01652105525135994,
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-0.0248... |
10,006,773 | The effects of serotonin antagonists were examined on the inhibition and excitation of nociceptive spinothalamic tract cells produced by brainstem stimulation with short (200 msec) or long (2 sec) stimulus trains. The inhibitory effects resulting from stimulation in either nucleus raphe magnus (NRM) or in the periaqued... | [
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0.022069085389375687,
0.03174879401922226,
0.0276076... |
10,006,774 | Effects of phosphatidylcholine administration to rats on choline in blood and choline and acetylcholine in brain. | [
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-0.02989836037158966,
-0... |
10,006,775 | Phosphatidylcholine (PCh) administered intragastrically to rats resulted in prolonged increase of the choline (Ch) concentration in plasma and erythrocytes. Plasma Ch was increased between 1 and 24 hr after administration of 10 mmol of PCh/kg with a peak level (256% of control) occurring 6 hr after treatment. The conce... | [
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0.07011809945106506,
0.0028266850858926773,
0.02094... |
10,006,776 | Characterization of vasopressin analgesia. | [
0.008258060552179813,
0.02848060242831707,
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0.0883023664355278,
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0.08... |
10,006,777 | Vasopressin produced analgesia in mice as estimated by using abdominal constriction tests (ED50 8.5 micrograms/kg i.v.) or hot plate method (ED50 63 micrograms/kg i.v.). However, vasopressin (10 micrograms/kg i.v.) produced no depression of locomotor activity in mice. Vasotocin had slight analgesic action; oxytocin or ... | [
0.0254688523709774,
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0.014365390874445438,
0.011383258737623692,
0.1092131... |
10,006,778 | Developmental changes in the accumulation of norepinephrine and the chronotropic effects of catecholamines in isolated rat atria as influenced by dietary lipid. | [
0.06928946822881699,
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-0.... |
10,006,779 | Pregnant rats were fed semisynthetic diets enriched in either saturated fat (coconut oil) or polyunsaturated fat (sunflower oil) and sympathetic function was observed in the resulting neonatal pups. The neuronal accumulation of [3H]norepinephrine was significantly decreased in atria from neonates (11, 24 and 37 days of... | [
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-0.07828272134065628,
-0.07... |
10,006,780 | Evidence for a prostaglandin link in the purinergic activation of rabbit bladder smooth muscle. | [
-0.01025232020765543,
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-0.03164505213499069,
0.1340... |
10,006,781 | Two independent pathways for contraction coupling are described for the cholinergic and ATP activation of rabbit detrusor smooth muscle. Both ATP (0.1 mM) and carbachol (1.0 microM) promote contraction of the rabbit detrusor muscle that can be selectively blocked, the cholinergic activation with atropine and an ATP-ind... | [
0.011602828279137611,
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0.039575692266225815,
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0.04305015504360199,
0.029799524694681168,
0.0194109920412302,
0.05680152773857117,
0.105041868984... |
10,006,782 | Diethylstilbestrol: placental transfer, metabolism, covalent binding and fetal distribution in the Wistar rat. | [
0.032119203358888626,
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0.02481774426996708,
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0.0... |
10,006,783 | The disposition of [14C]diethylstilbestrol (DES) was investigated in the near-term pregnant Wistar rat. Both constant maternal i.v. infusions and direct fetal i.p. injections of [14C]DES were utilized as exposure routes. Maternal femoral vein infusions (total dose: 0.3-0.4 mg of DES/kg of maternal b.wt.) resulted in a ... | [
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-... |
10,006,784 | Effects of bromocriptine on single nephron and whole-kidney function in rats. | [
0.008532312698662281,
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0.037971131503582,
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0.02243882045149803,
0.030284... |
10,006,785 | Bromocriptine (BRC) is a semisynthetic ergot alkaloid possessing dopamine agonistic activity. We had previously observed significant changes in renal hemodynamics in rats pretreated with BRC to suppress endogenous prolactin plasma levels. To investigate further the effects of BRC on single nephron and whole-kidney func... | [
0.015156936831772327,
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... |
10,006,786 | Relationship of tissue nonprotein/sulfhydryls to the acute toxic effects of 1,2-dibromo-3-chloropropane. | [
0.01872706040740013,
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0.0033263990189880133,
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0.096... |
10,006,787 | Subcutaneous administration of the nematocide, 1,2-dibromo-3-chloropropane (DBCP), to adult, male, Fischer 344 rats transiently depleted hepatic and caput (head) epididymal nonprotein sulfhydryl (NPS) contents. NPS concentrations in the testis and kidney were not lowered by DBCP. Liver, kidney and testis all exhibited ... | [
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0.0031008741352707148,
0.015491836704313755,
0.02550152689218521,
0.... |
10,006,788 | Pharmacological activities of heparins obtained from different tissues: enrichment of heparin fractions with high lipoprotein lipase, antihemolytic and anticoagulant activities by molecular sieving and antithrombin III affinity chromatography. | [
-0.009314130991697311,
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-0.02353387326002121,
0.0... |
10,006,789 | The pharmacological activities of 14 heparins prepared from bovine and hog tissues and heparin fractions obtained by molecular sieving on sephacryl S-200 and antithrombin III affinity chromatography are reported. Two groups of heparins can be distinguished regarding the lipoprotein lipase releasing activity (LPL) and t... | [
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0.006775252055376768,
-0.031009357422590256,
0.0... |
10,006,790 | Protective effect of propylthiouracil independent of its hypothyroid effect on acetaminophen toxicity in the rat. | [
0.07062512636184692,
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0.020159410312771797,
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0.08328703790903091,
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0.030944878235459328,
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0.049544911831617355,
0.02308564819395542,
0.0529... |
10,006,791 | Time perception in relation to pulse rate in healthy males. | [
-0.003838217118754983,
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-0.012257920578122139,
0.019778402522206306,
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0.037249088287353516,
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0.... |
10,006,792 | Time estimation by the production method and pulse rate under resting but attentive conditions were investigated in 92 healthy males. Subjects estimated intervals of 30, 60, and 180 sec following which they participated in an hour-long watchkeeping task during which pulse rate was recorded. Both the time estimates and ... | [
0.03309258818626404,
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0.02089676447212696,
0.028490016236901283,
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0.008105775341391563,
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0.008192773908376694,
-0.06029955670237541,
-0.04314371570944786,
0.01... |
10,006,793 | Validity of biorhythms for predicting death. | [
0.0245978981256485,
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0.09734481573104858,
0.05831682309508324,
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0.04567181318998337,
0.06950540840625763,
0.04490255191922188,
-0.005324322264641523,
-0.08877729624509811,
-0.05282184109091759,
0.0636909... |
10,006,794 | Overweight as master status: a replication. | [
0.03652264550328255,
0.016551408916711807,
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0.09522883594036102,
0.006378290243446827,
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0.0225848201662302,
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0.027147840708494186,
... |
10,006,795 | The study reported here is a replication of an earlier study exploring association of body image with other personality characteristics. In both studies it was predicted that overweight body image would be associated with more negative personality characteristics than normal weight body image, and evidence was found su... | [
0.08416243642568588,
0.09542738646268845,
0.04977741092443466,
0.09422579407691956,
0.010207180865108967,
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0.04536023736000061,
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0.023774582892656326,
0.0039413... |
10,006,796 | The effects of intent, reason, and harm on attribution of aggressiveness. | [
0.05528155714273453,
0.026931487023830414,
-0.029929010197520256,
0.025336848571896553,
0.07234171032905579,
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0.02130037732422352,
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0.0014114703517407179,
0.03405822813510895,
0.005880103446543217,
0.009158680215477943,
0.03659... |
10,006,797 | Phaeochromocytomas of the bladder. | [
-0.07367021590471268,
0.019779982045292854,
-0.06457904726266861,
0.04402017593383789,
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0.06734926253557205,
0.027431564405560493,
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0.013268819078803062,
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0.0... |
10,006,798 | Phaeochromocytomas of the bladder are rare, only about 100 cases having been reported previously. Four adults with these lesions have been managed at Hammersmith Hospital in the past 10 years. Three patients had hypertension, together with syncopal attacks and/or headaches, induced by micturition. The fourth patient pr... | [
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-0.004552292637526989,
-0.048814136534929276,
... |
10,006,799 | The tourniquet in operations on the knee: a review. | [
-0.04779129475355148,
0.08883616328239441,
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0.05863064527511597,
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0.07817583531141281,
-0.02827010117471218,
0.075314... |
10,006,800 | Zinc deficiency developing in treatment for thalassaemia. | [
-0.056855861097574234,
0.09953206777572632,
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0.07642637938261032,
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0.00444299541413784,
0.038199834525585175,
-0.014... |
10,006,801 | Juvenile dermatomyositis: a review. | [
-0.028312575072050095,
0.02879558876156807,
-0.0043863882310688496,
-0.017702382057905197,
-0.05549685284495354,
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0.05174734443426132,
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0.04813814535737038,
0.07165277749300003,
-0.03246629238128662,
0.00428951857611537,
0.1... |
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