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2005 after a detailed polyphasic study and reclassification on the genus thermoactinomyces
. at present
the genus laceyella has four recognized species namely ; laceyella putida
, l. sacchari , type species of the genus laceyella
, laceyella sediminis
and laceyella tengchongensis
.
cells are aerobic , no... | we report the 3.3-mb draft genome of laceyella sacchari strain gs 1 - 1 , isolated from hot spring water sample , chumathang , leh , india . draft genome of strain gs 1 - 1 consists of 3 , 324 , 316 bp with a g + c content of 48.8% and 3429 predicted protein coding genes and 75 rnas .
geobacillus thermodenitrifica... |
the basic fasting protocol is to transfer the fish , at their normal density , to a clean tank , then withhold food
. for longer - term fasting that requires more rigorous conditions ( e.g. , for blood glucose studies ) , see additional considerations in the discussion .
for a 100 ml volume , dissolve the following... | a convenient method for chemically treating zebrafish is to introduce the reagent into the tank water , where it will be taken up by the fish .
however , this method makes it difficult to know how much reagent is absorbed or taken up per fish .
some experimental questions , particularly those related to metabolic s... |
neuropathic pain , defined as pain arising as a direct consequence of a lesion or a disease affecting the somatosensory system,1 is a disorder that can considerably affect quality of life for patients .
even though up to 5% of the general population could be involved , treatment of neuropathic pain continues to be c... | post - herpetic neuralgia ( phn ) is neuropathic pain persisting after an acute episode of herpes zoster , and is associated with severe pain and sensory abnormalities that adversely affect the patient s quality of life and increase health care costs .
up to 83% of patients with phn describe localized neuropathic pai... |
nephrotic syndrome ( ns ) in children is usually idiopathic , but may also be triggered by immunological stimuli like vaccination , infection , insect sting , or pollen hypersensitivity .
humoral and cellular immune function studies suggest that abnormal immune response is the probable cause in this clinical entity .... | the occurrence of nephrotic syndrome following a bee sting is rarely reported in the literature .
hypersensitivity is believed to be the precipitating factor for the renal disease .
we report a two - year - old boy , who developed generalized edema and decreased urine output , seven days after a bee sting . physica... |
emergency department ( ed ) use is common for both children and adults not only in a country without universal health insurance like the united states but also in countries like france where virtually all residents have health insurance . in 2006
the annual rate of ed visits for parisian children less than 2 years ... | parents frequently bring their children to general or pediatric emergency departments ( eds ) , even though many of these visits are judged by others to be nonurgent and inappropriate .
this study examined the motives behind parents ' decisions to take their children to a pediatric emergency department ( ped ) . at... |
south carolina , like many other cities and states that have historically had few latinos , has experienced recent surges in immigration and now has small informal enclaves and social structures .
many latinos in these new communities may lack documentation for us residency . consequently , our sampling design took i... | we investigated in a sample of latinos the practices of antimicrobial drug importation and use of nonprescribed antimicrobial drugs . in interviews conducted with 219 adults , we assessed health beliefs and past and present behaviors consistent with acquiring antimicrobial drugs without a prescription in the united sta... |
the author receives funding from the swedish research council , the ragnar sderbergs stiftelse , the novonordisk foundation and lund university .
the author is also part of the following strategic research consortia in diabetes : the linnaeus lund university diabetes center ( ludc ) funded by the swedish research cou... | common genetic variations in the gene encoding transcription factor 7-like 2 ( tcf7l2 ) reveal the strongest association with type 2-diabetes known to date . these lead to impaired insulin production and output , but the mechanisms of disease
remain incompletely known . in this issue of diabetologia ,
two publicati... |
acquired retinal astrocytoma is a benign glial intraretinal tumor.1 it is considered the retinal equivalent of low - grade brain astrocytomas . despite its benign cytology , it can show progressive growth and behave as a locally aggressive malignant tumor .
the clinical course can be complicated with exudative retina... | photodynamic therapy ( pdt ) has been used for treatment of various intraocular tumors including choroidal hemangioma , vasoproliferative tumor , amelanotic choroidal melanoma and choroidal neovascular membrane due to choroidal osteoma .
this case report documents the effect of pdt for a presumed acquired retinal ast... |
hemangioblastoma ( hb ) of the central nervous system is a benign neoplasm of the central nervous system that usually involves the brain and spinal cord .
it may occur sporadically or in association with von hippel - lindau ( vhl ) disease ( 1 - 5 ) . in sporadic , non - vhl cases ,
the tumors are usually solitary ... | we report a very rare case of hemangioblastomatosis that developed after surgical removal of a solitary cerebellar hemangioblastoma ( hb ) . a 51-yr - old man presented with back pain 10 yr after undergoing surgery for cerebellar hb .
magnetic resonance imaging showed numerous mass lesions along the entire neuraxis a... |
in the recent years , the identification of genes involved in the modulation of inflammatory and apoptotic processes and the improved understanding of mechanisms linked to the aberrant activation of the inflammasome , amultiprotein intracytoplasmatic scaffold complex synthesizing the biologically active interleukin- ( ... | monogenic autoinflammatory syndromes ( maiss ) are caused by innate immune system dysregulation leading to aberrant inflammasome activation and episodes of fever and involvement of skin , serous membranes , eyes , joints , gastrointestinal tract , and nervous system , predominantly with a childhood onset .
to date , ... |
brain tumors located in the suprasellar region are frequently found in childhood , and
include craniopharyngioma , germinoma , optic nerve glioma and histiocytosis ( 1 ) . following the extension of the tumor or intervening
procedures , such as surgery , chemotherapy and radiation , considerable damage to the
hyp... | weight gain is a common sequela of suprasellar tumors , referred to as hypothalamic
obesity .
we undertook an evaluation of obesity and metabolic aberrations among patients
treated at our institute . during the 12 mo from apr .
2005 , 23 patients ( 10 males and 13
females ) with remitted suprasellar tumors at... |
mechanical valve thrombosis ( mvt ) may cause valve dysfunction , and its onset may be acute or gradual , according to the nature of thrombi ( rapid or slow growth ) and involvement of hinge point ( abrupt or insidious ) .
edmunds defined mechanical valve thrombosis as a complication attributable to any type of throm... | in the present study , the authors investigated the management of mechanical valve thrombosis ( mvt ) . from january 1981 through march 2006 , 2,908 mechanical valve replacements were performed in 2,298 patients at our institution . twenty ( 0.87% ) patients presented with mvt , 14 ( 70.0% ) were women , and the mean a... |
squamous cell carcinoma ( scc ) of the thyroid is an extremely rare disease accounting for less than 1% of all thyroid tumors . in the world health organization classification
, squamous cell carcinoma thyroid is defined as scc of the thyroid should be composed entirely of tumor cells with squamous differentiation .... | primary squamous cell carcinoma of the thyroid is an extremely rare neoplasm with aggressive behavior . until date , only around 60 cases have been reported in the literature .
primary treatment of the patient is radical surgery . with optimum treatment survival
is not more than 6 months in this aggressive malignan... |
although levodopa ( ld ) still remains the gold standard for symptomatic efficacy in reducing the motor symptoms of parkinson s disease ( pd),1 its long - term use is associated with the development of potentially disabling motor complications , including response oscillations as well as drug - induced dyskinesias ( ld... | the aim of this article is to provide a short review of the most relevant pharmacological and clinical data on pramipexole extended release ( er ) as well as to address the clinical utility and potential advantages of a once - daily formulation especially in the treatment of early parkinson s disease ( pd ) .
pramipe... |
glutaric aciduria type i is caused by deficiency of the enzyme glutaryl coa - dehydrogenase ( gcdh ) in the metabolic pathway of lysine , hydroxylysine , and tryptophan , leading to an accumulation of glutaric acid ( ga ) and its derivative 3-hydroxy glutaric acid ( 3ohga ) ( funk et al . 2005 ; harting et al .
2-hyd... | concentrations of glutarate ( ga ) and its derivatives such as 3-hydroxyglutarate ( 3ohga ) , d- ( d-2ohga ) and l-2-hydroxyglutarate ( l-2ohga ) are increased in plasma , cerebrospinal fluid ( csf ) and urine of patients suffering from different forms of organic acidurias .
it has been proposed that these derivative... |
fibromyalgia is a chronic pain syndrome of unknown origin , estimated to affect 25% in all populations studied ( raspe , 1992 ; wolfe et al . , 1995 ;
fibromyalgia is characterized by widespread pain , fatigue , poor sleep , and dyscognition ( wolfe et al . , 2010 ) and is often also associated with mood disorders su... | fibromyalgia is a chronic pain syndrome characterized by widespread pain , fatigue , and memory and mood disturbances . despite advances in our understanding of the underlying pathophysiology
, treatment is often challenging .
new research indicates that changes in functional connectivity between brain regions , as... |
several malignant tumours can metastasize to the colon , including those of the stomach , breast , ovary , cervix , kidney , lung , prostate and skin .
clinical symptoms and signs may suggest the diagnosis , but one third of such patients are asymptomatic and the diagnosis may be an incidental finding at autopsy .
... | introductioncolonic metastases are rare , and usually secondary from malignant tumours of the stomach , breast , ovarian , cervix , kidney , lung , prostate , or skin . around one third
are asymptomatic or found only at autopsy.case reporta middle - aged male smoker , who had a small cell carcinoma of the lung diagno... |
the use of dental implants has revolutionized prosthodontics and the fixed treatment options that can be offered to patients .
high survival rates and long - term predictability for clinically loaded endosseous implants have been consistently reported resulting in one of the most successful treatment modalities in de... | to evaluate the sealing capability of external hexagon implant systems and assess the marginal fit , two groups ( n = 10 each ) were employed : sin ( sistema de implantes nacional , brazil ) and osseotite , ( biomet 3i , usa ) .
sealing capability was determined by placing 0.7 l of 1% acid - red solution in the impl... |
postmenopausal osteoporosis is a systemic skeletal condition that affects many millions of women around the world .
the national institutes of health consensus conference defined osteoporosis as a disease of increased skeletal fragility accompanied by microarchitectural deterioration and low bone mineral density ( a ... | the aim of this longitudinal study is to present data from 76 female patients treated with bisphosphonates ( bps ) for postmenopausal osteoporosis and referred to the unit of oral diagnosis and day surgery of the university of milano for diagnosis and treatment .
all patients received a thorough oral examination .
... |
eukaryotic cells depend on vesicle - mediated endocytosis and secretion to interact and communicate with their environment .
such membrane - based cellular processes are dynamic as well as closely interconnected and thus require complex cellular logistics .
small vesicles , for example , cycle between the endoplasm... | long - distance trafficking of membranous structures along the cytoskeleton is crucial for secretion and endocytosis in eukaryotes .
molecular motors are transporting both secretory and endocytic vesicles along polarized microtubules . here
, we review the transport mechanism and biological function of a distinct s... |
fiber post systems are routinely used in restorative dentistry . in the absence of solid consensus
as regards the selection criteria of the post system , clinicians often succumb to marketing tactics as opposed to clinical evidence .
this study attempts to bridge this gap by using finite element analysis model to a... | aims and objectives : to study the stress concentrations in endodontically treated maxillary central incisor teeth restored with 3 different fiber post systems subjected to various oblique occlusal loads.materials and methods : fem analysis was used to analyze stress concentrations generated in maxillary anterior teeth... |
in most of the peer review publications in the late 17 century , authorship of papers generally used to be autonomous and was attributed to the sponsors ( 1 ) .
however , now the readers wish to know who paid for research and who did the work .
problems with authorship persist everywhere despite the international c... | abstractbackgroundthe objective of this study was to assess the knowledge and views of faculty members on criteria for authorship by international committee of medical journal editors ( icmje ) , their current practice of choosing the authors , views on gift authorship and problems they had faced concerning authorship.... |
the reveal registry is a longitudinal registry involving 54 pulmonary hypertension centers in the united states ( e - appendix 1 ) .
diagnosis was defined as the date of diagnostic right - sided heart catheterization ( rhc ) occurring at or before the date of enrollment .
patients with new diagnoses were define... | background : patients with pulmonary arterial hypertension ( pah ) associated with systemic sclerosis ( ssc - apah ) experience higher mortality rates than patients with idiopathic disease and those with other connective tissue diseases ( ctd - apah ) .
we sought to identify unique predictors of mortality associated ... |
cerebral palsy is a nonprogressive central nervous system disorder that results in physical impairments and functional limitations that change as the children grow older . among a large number of instruments [ 24 ] , for measuring the physical ability of children with cp , the gross motor function classification system... | objective . to determine
if gait waveform could discriminate children with diplegic cerebral palsy of the gmfcs levels i and ii .
patients .
twenty - two children with diplegia , 11 classified as level i and 11 as level ii of the gmfcs , aged 7 to 12 years .
methods .
gait kinematics included angular displace... |
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