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2,600 | 7,598 | Newborn screening for sickle cell disease. When is an infant 'lost to follow-up'?
Success of programs to screen newborns for sickle cell disease depends on timely follow-up.
Education regarding fever and splenic palpation, and initiation of prophylactic penicillin therapy, will reduce morbidity and mortality and shou... | C15 |
2,601 | 873 | The relationship of pemphigus to neoplasia.
A statistically increased incidence of malignancy has been observed in patients with pemphigus.
A review of the literature reveals 42 cases of nonthymic malignancies and 18 cases of thymic malignancies.
A significant predominance of men, with mean age at onset of 50 years,... | C15 |
2,602 | 9,227 | Edgar J Poth lecture. Pathogenesis, diagnosis, and treatment of thrombosis.
Thrombosis and its major sequela, embolism, continue to contribute significantly to morbidity and mortality, both as primary disorders and as complications of other systemic systems.
The understanding of the etiology of thromboembolism and th... | C15 |
2,603 | 2,202 | Incubation of platelet concentrates before transfusion does not improve posttransfusion recovery.
Incubation of stored platelet concentrates (PCs) at 37 degrees C for 1 hour has been reported to result in a better morphology score and improved platelet recovery.
A study was conducted in adult patients with leukemia t... | C15 |
2,604 | 2,147 | Heparin-induced thrombocytopenia in patients who undergo open heart surgery.
To determine whether heparin-dependent antiplatelet antibodies (HAAb) have an effect on morbidity and/or mortality rates, we reviewed the cases of 3438 patients who underwent open heart surgery from 1981 to 1989.
Forty-six patients (1.3%) ha... | C15 |
2,605 | 6,317 | Total and differential leukocyte counts in clinically well children. Information or misinformation?
To determine whether the total and differential leukocyte count is of value as a case-finding test, we applied the evaluation criteria developed by the US Preventive Services Task Force.
The criteria comprise review of... | C15 |
2,606 | 9,899 | A phase I study of recombinant human interferon-alpha 2a or human lymphoblastoid interferon-alpha n1 and concomitant zidovudine in patients with AIDS-related Kaposi's sarcoma.
To determine the safety, maximum tolerated dose, and preliminary efficacy of concomitant interferon-alpha and zidovudine therapy in AIDS-relate... | C15 |
2,607 | 6,143 | Life-threatening, antiglobulin test-negative, acute autoimmune hemolytic anemia due to a non-complement-activating IgG1 kappa cold antibody with Pra specificity.
A 21-year-old man with fulminant cold autoantibody hemolytic anemia (CAHA) was hospitalized with hemoglobinemia, hemoglobinuria, hemoglobin concentration of ... | C15 |
2,608 | 5,337 | A chronic granulomatous syndrome of unknown origin.
A small clinically distinct group of patients with widespread tissue granulomata are described.
The principal presenting symptoms are malaise, fever, and weight loss, although a wide variety of complaints are documented.
Pulmonary involvement is uncommon.
The gran... | C15 |
2,609 | 6,798 | Myasthenic thymus and thymoma are selectively enriched in acetylcholine receptor-reactive T cells.
We compared T-cell proliferative responses to acetylcholine receptor (AChR) and to purified protein derivative (PPD) (of tuberculin) of hyperplastic thymus, thymoma, and blood cells from patients with myasthenia gravis (... | C15 |
2,610 | 9,364 | Extramedullary hematopoiesis in a bronchial carcinoid tumor. An unusual complication of agnogenic myeloid metaplasia.
A case of bronchial carcinoid tumor with foci of extramedullary hematopoiesis is presented.
The patient had a 6-year history of agnogenic myeloid metaplasia and hepatosplenomegaly.
All three hematopo... | C15 |
2,611 | 4,999 | Pediatric blunt liver injury and coagulopathy managed with packs and a silo: case report.
Packing the abdomen can be lifesaving when severe hepatic trauma is complicated by refractory hypothermia, coagulopathy, and continuing hemorrhage requiring large-volume transfusion.
This report describes the successful use of a... | C15 |
2,612 | 2,986 | Eosinophilia-myalgia syndrome associated with L-tryptophan ingestion. Analysis of four patients and implications for differential diagnosis and pathogenesis
Four patients fulfilling the case definition for eosinophilia-myalgia syndrome are described, including one whose disease began in 1986.
Each displayed a variet... | C15 |
2,613 | 7,889 | Elevated serum procollagen III aminopeptide levels in sarcoidosis.
Procollagen III aminopeptide (P-III-P), a peptide released during the conversion of type III procollagen to type III collagen, is considered a potential marker of fibroblast activity in a variety of pulmonary and extrapulmonary diseases.
The aim of th... | C15 |
2,614 | 849 | Neutrophilic dermatosis with myelodysplastic syndrome: nuclear segmentation anomalies of neutrophils in the skin lesion and in peripheral blood.
Neutrophilic dermatosis developed in two patients with myelodysplastic syndrome.
Biopsy specimens of their skin lesions showed marked infiltration by neutrophils with nuclea... | C15 |
2,615 | 9,283 | Severe anemia is an important negative predictor for survival with disseminated Mycobacterium avium-intracellulare in acquired immunodeficiency syndrome [published erratum appears in Am Rev Respir Dis 1991 Feb;143(2):451]
Disseminated Mycobacterium avium-intracellulare (MAI) in patients with the acquired immunodeficie... | C15 |
2,616 | 9,641 | Surgical presentation of Kawasaki disease (mucocutaneous lymph node syndrome).
Five patients with Kawasaki disease (mucocutaneous lymph node syndrome) are reported whose varied presentations included acute abdominal pain, peripheral arterial aneurysms, digital gangrene and sterile pyuria and whose presenting pathology... | C15 |
2,617 | 9,335 | Peripheral neuropathy associated with eosinophilia-myalgia syndrome.
In 1989, the Centers for Disease Control recognized the existence of an epidemic illness characterized by myalgia and eosinophilia in individuals taking preparations containing L-tryptophan.
We evaluated 3 patients with eosinophilia-myalgia syndrome... | C15 |
2,618 | 8,282 | Obesity and vaginal hysterectomy.
A retrospective study was done of 471 consecutive vaginal hysterectomies done in a three-year period.
Three groups of patients--239 normal to 9% overweight, 132 10-24% overweight and 100 greater than or equal to 25% overweight--were compared.
Surgical difficulties were similar in al... | C15 |
2,619 | 3,282 | Enhanced endogenous leukotriene biosynthesis in patients treated with granulocyte-macrophage colony-stimulating factor.
The hematopoietic cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF) is being used in clinical trials for its potential in the treatment of hematopoietic insufficiency due to various ... | C15 |
2,620 | 2,937 | Analysis of prognostic factors and clinicopathological staging of thymoma
The prognostic value of four clinical variables (age and sex of patients, association with myasthenia gravis, and clinical stage) and histological type was analyzed in 83 consecutive patients with thymoma, histologically classified as cortical,... | C15 |
2,621 | 5,893 | In vitro colony culture and chromosomal studies in hepatic and portal vein thrombosis--possible evidence of an occult myeloproliferative state.
We have studied the prevalence of an underlying myeloproliferative state in 20 patients with either hepatic or portal vein thrombosis.
Using conventional clinical and laborat... | C15 |
2,622 | 3,379 | Successful treatment of metastatic thymic carcinoma with cisplatin, vinblastine, bleomycin, and etoposide chemotherapy.
Thymic carcinomas are rare malignant neoplasms of the thymic epithelium that are distinguished from the malignant thymomas by the presence of cytologic atypia.
Thymic carcinomas may metastasize outs... | C15 |
2,623 | 7,911 | Ear involvement in the yellow nail syndrome.
Recognized features of the yellow nail syndrome include yellow nails, lymphedema, and pleural effusions.
We report a patient with the additional feature of keratosis obturans, which may be a manifestation of this syndrome in the external ear. | C15 |
2,624 | 8,210 | Increased incidence of monoclonal gammopathy of undetermined significance in blacks and its age-related differences with whites on the basis of a study of 397 men and one woman in a hospital setting.
Serum samples from 398 individuals (270 whites and 128 blacks) exhibiting quantitatively normal amounts of five typical... | C15 |
2,625 | 6,011 | Synchronous Hodgkin's disease and myelofibrosis terminating with granulocytic sarcoma and acute megakaryocytic leukemia.
Our patient had stage IIIAI Hodgkin's disease with synchronous myelofibrosis and myeloid metaplasia.
A slowly progressive myeloproliferative disease developed over 9 1/2 years and terminated in a p... | C15 |
2,626 | 4,820 | Early hospital discharge of children with cancer treated for fever and neutropenia: identification and management of the low-risk patient.
Children with leukemia and solid tumors are often hospitalized for empiric broad-spectrum antibiotic therapy because of fever during periods of chemotherapy-induced neutropenia.
C... | C15 |
2,627 | 8,260 | Eosinophilic meningitis: cause of a chronic pain syndrome.
Three tourists developed eosinophilic meningitis after visiting the Fijian Islands.
Two had a severe and long lasting illness with chronic intractable pain.
In one patient electrophysiological studies and MRI scan of the brain were abnormal and provided evid... | C15 |
2,628 | 8,641 | Kawasaki disease: echocardiographic features in 91 cases presenting in the United Kingdom.
Ninety-one patients with Kawasaki disease were examined by cross sectional echocardiography between 1980 and 1988.
In the 75 patients evaluated during the acute phase of the illness (the first month), the first echocardiographi... | C15 |
2,629 | 236 | Primary leptomeningeal B-cell lymphoma in a 8-year-old child.
A case of primary leptomeningeal B-cell lymphoma in an 8-year-old, previously healthy child is described.
The child was found to have hypogammaglobulinemia, and the Epstein-Barr virus genome was identified in cultured tumor cells despite blood serology bei... | C15 |
2,630 | 2,444 | Hepatic giant cavernous hemangioma with microangiopathic hemolytic anemia and consumption coagulopathy.
We describe a case of hepatic giant cavernous hemangioma with both microangiopathic hemolytic anemia (MAHA) and consumption coagulopathy, but without thrombocytopenia, which was completely cured by surgical resectio... | C15 |
2,631 | 946 | Increased serum IgE and increased prevalence of eosinophilia in 9-year-old children of smoking parents.
We studied the relationship of serum IgE levels and eosinophil counts with passive smoking in 9-year-old, nonselected children from three Italian towns near Rome.
Male children of smoking parents had a significantl... | C15 |
2,632 | 8,669 | Intravenous immunoglobulin in virus associated haemophagocytic syndrome.
A 1 year old boy with virus associated haemophagocytic syndrome caused by cytomegalovirus infection is described.
Persistent severe thrombocytopenia responded to repeated intravenous infusions of immunoglobulin. | C15 |
2,633 | 5,627 | Thrombocytosis after pneumonia with empyema and other bacterial infections in children.
Thrombocytosis is seen in association with many conditions, including infectious diseases.
We studied thrombocytosis after severe bacterial infections, particularly pneumonia with empyema in children.
A systematic survey of the p... | C15 |
2,634 | 3,042 | Heterotopic tissue in lymph nodes. An unrecognized problem.
Heterotopic tissue in lymph nodes is both unknown to clinicians and a potential source of confusion with metastatic disease.
We reviewed the English literature and found 289 cases of heterotopic tissue in lymph nodes.
The majority (84%) of these patients we... | C15 |
2,635 | 8,528 | Asymptomatic rhabdomyolysis of unknown etiology.
A 7-year-old boy developed rhabdomyolysis with a peak creatine phosphokinase level of 261,400 IU/L after his appendectomy.
These abnormalities occurred following a 2-3-day illness consisting of upper respiratory tract symptoms, fever, and abdominal pain mimicking acute... | C15 |
2,636 | 3,711 | Fluosol DA-20 in the treatment of severe anemia: randomized, controlled study of 46 patients.
We evaluated the safety and efficacy of Fluosol DA-20% (FDA) as a blood substitute in the treatment of severe anemia.
Thirty-six patients received either FDA (n = 21) or crystalloid/hydroxyethyl starch (CHS) (n = 15) as part... | C15 |
2,637 | 9,137 | Ulcerative lesions and herpes simplex virus type 2 in a patient with Evan's syndrome.
We have described a case of herpes genitalis in a patient with Evans's syndrome who had violaceous macules leading to deep ulcerations.
This case serves as a reminder that HSV infection may be atypical and have an unusual course in ... | C15 |
2,638 | 314 | Immunologic abnormalities of juvenile arthritis.
Many immunologic abnormalities have been found in children with all forms of chronic arthritis, but few are clinically useful or well understood.
However, in children with arthritis it is important to distinguish among those with rheumatoid factor, antinuclear antibodi... | C15 |
2,639 | 7,460 | Acute splenic sequestration crisis in two adults with sickle cell disease: US, CT, and MR imaging findings.
Acute splenic sequestration crisis (ASSC) is a rare complication in adults with sickle cell disease that is diagnosed clinically by means of sudden splenic enlargement and a rapid fall in hematocrit.
Two cases ... | C15 |
2,640 | 3,308 | Impaired iron uptake and transferrin binding by erythroblasts in the anaemia of rheumatoid arthritis.
Serum and bone marrow from 18 patients with rheumatoid arthritis (RA) and five healthy controls were studied in order to establish a possible role of impaired iron uptake and transferrin binding by erythroblasts in th... | C15 |
2,641 | 2,980 | Pregnancy in women with immune thrombocytopenic purpura.
Thirty-six women with immune thrombocytopenic purpura were studied during 37 pregnancies, and maternal characteristics with predictive value for the fetal platelet count were determined.
Nine neonates were thrombocytopenic, with a platelet count of less than 50... | C15 |
2,642 | 3,746 | Cardiac abnormalities in children with sickle cell anemia.
The cardiac status of 64 children (ages 0.2 to 18 yr) with sickle cell anemia documented by hemoglobin electrophoresis was evaluated by echocardiography.
Left atrial, left ventricular and aortic root dimensions were significantly increased in over 60 percent ... | C15 |
2,643 | 6,426 | Twin-twin transfusion syndrome.
Twin-twin transfusion syndrome associated with acute polyhydramnios in one sac and severe oligohydramnios in the other, which characteristically is diagnosed between 18 and 28 weeks, is associated with a high mortality rate for the involved twins.
Patients who are managed without inter... | C15 |
2,644 | 6,014 | Isolated erythroid hypoplasia and renal insufficiency induced by long-term griseofulvin therapy.
We describe a patient with hematuria, pyuria, eosinophiluria, decreased renal function, and severe anemia that developed while she was receiving chronic therapy with griseofulvin for onychomycosis.
We offer evidence that ... | C15 |
2,645 | 389 | Cyclosporine and chronic sarcoidosis.
Two patients with progressive sarcoidosis who had poor responses and side effects from corticosteroid therapy were treated with cyclosporine.
Cyclosporine suppressed conventional markers of inflammation and there was clinical improvement in one patient, but the disease recurred w... | C15 |
2,646 | 5,830 | Hypodense eosinophils and interleukin 5 activity in the blood of patients with the eosinophilia-myalgia syndrome.
The recent recognition of the eosinophilia-myalgia syndrome (EMS) associated with the ingestion of L-tryptophan prompted an analysis of the peripheral blood eosinophil phenotypes and of the serum eosinophi... | C15 |
2,647 | 2,207 | Abnormal membrane physical properties of red cells in McLeod syndrome.
McLeod red cells (RBCs) lack Kx antigens and have weak expression of the Kell antigens.
Individuals who carry the McLeod phenotype have acanthocytic RBCs and a compensated hemolytic state.
To elucidate the role of the protein on which the Kx anti... | C15 |
2,648 | 9,446 | Effects of recombinant human erythropoietin on T lymphocyte subsets in hemodialysis patients.
Lymphocyte subpopulations were studied by immunofluorescence staining with monoclonal antibodies and laser flow cytometry in the blood of 23 hemodialysis patients before and after 3 months of treatment with recombinant human ... | C15 |
2,649 | 7,713 | Ticlopidine treatment reduces the progression of nonproliferative diabetic retinopathy. The TIMAD Study Group.
The Ticlopidine Microangiopathy of Diabetes study (TIMAD), a randomized, double-masked, placebo-controlled trial, assessed the effect of this antiplatelet agent (ticlopidine hydrochloride) in reducing the pro... | C15 |
2,650 | 6,310 | Histiocytosis X. S-100 protein, peanut agglutinin, and transmission electron microscopy study.
Twenty-seven cases of histiocytosis X (HX) for which paraffin blocks were available were studied with the use of S-100 protein immunohistochemistry, peanut agglutinin affinity histochemistry, and transmission electron micros... | C15 |
2,651 | 8,217 | Rheologic properties of mixed hemoglobin gels: deoxyhemoglobins S and F.
To obtain new information concerning the behaviors--and in turn, the structures--of gels formed from mixtures of S and F hemoglobins, their rheologic properties have been characterized by stress relaxation.
The variables manipulated were (1) ini... | C15 |
2,652 | 3,737 | Serum concentration of soluble interleukin-2 receptor as a sensitive parameter of disease activity in sarcoidosis.
We investigated the clinical value of measuring serum concentrations of soluble IL-2R in monitoring sarcoidosis.
Serum concentrations of soluble IL-2R were measured in 70 patients with sarcoidosis.
The ... | C15 |
2,653 | 3,773 | The malignancy-sarcoidosis syndrome.
In a retrospective review of six patients with malignancy preceding sarcoidosis, we found four cases of malignant lymphoproliferative disease (LD) and one case each of ovarian cancer and breast cancer.
The median interval from onset or relapse of malignancy to sarcoidosis was nine... | C15 |
2,654 | 7,788 | Splenic rupture in a human immunodeficiency virus-infected patient with primary splenic lymphoma.
Splenic rupture presenting as primary malignant lymphoma of the spleen is a rare event.
We report such an occurrence in a young man who had a primary B-cell immunoblastic lymphoma of the spleen and was found to be HIV-po... | C15 |
2,655 | 6,253 | Impaired thermoregulation and thyroid function in iron-deficiency anemia.
Ten women with iron-deficiency anemia, 8 with depleted iron stores (nonanemic), and 12 control women, all of similar body fatness, were exposed to a 28 degrees C water bath to test the hypothesis that iron-deficiency anemia impairs thermoregulat... | C15 |
2,656 | 9,934 | Diclofenac induced immune thrombocytopenia.
We describe a patient with scleroderma who developed immune thrombocytopenia secondary to diclofenac on 2 occasions.
Platelet count returned to normal with cessation of diclofenac and institution of prednisone. | C15 |
2,657 | 3,758 | Anti-Kveim monoclonal antibody. New monoclonal antibody reacting to epithelioid cells in sarcoid granulomas.
A monoclonal antibody to the sarcoid granulomagenic agent contained in Kveim suspension was prepared by immunizing mice with Kveim suspension.
One monoclonal antibody (IHY-1) that reacted with the epithelioid ... | C15 |
2,658 | 5,636 | Antigenic recognition by intravenous gamma-globulin of selected bacteria isolated from throats of patients with Kawasaki syndrome.
Kawasaki syndrome (KS) or mucocutaneous lymph node syndrome is an acute febrile exanthematous illness of unknown etiology.
Therapy with intravenous gamma-globulin (IVGG) results in rapid ... | C15 |
2,659 | 5,251 | Renal cell carcinoma associated with sarcoidlike tissue reaction.
A 60-year-old man was referred to our institution with the diagnosis of sarcoidosis.
Because of several months' complaint of right flank pain and weight loss, the patient had consulted his local physician.
After an extensive workup revealed only chole... | C15 |
2,660 | 2,201 | Detection of drug-dependent, platelet-reactive antibodies by antigen-capture ELISA and flow cytometry.
The effectiveness of flow cytometry in the detection of drug-dependent, platelet-reactive antibodies was investigated.
In studies of seven sera known to contain quinine- or quinidine-dependent, platelet-reactive ant... | C15 |
2,661 | 333 | Wiskott-Aldrich syndrome. A case report.
This paper presents a report on a child with Wiskott-Aldrich syndrome.
The clinical picture and laboratory findings are characteristic of this disease.
The prevailing symptoms have included recurrent respiratory and alimentary tract infections, seborrhic dermatitis-type skin ... | C15 |
2,662 | 9,038 | Congenital abnormalities of the lymphatic system: a new clinical classification.
The numerous clinical presentations of congenital abnormalities of the lymphatic system in children and the confusing terminology used to describe their pathologic diagnoses impede the physician's understanding of the condition.
The clin... | C15 |
2,663 | 7,253 | Iron: nutrition monitoring and nutrition status assessment.
The majority of anemias in the United States are characterized by low mean corpuscular volume and thus are classified as microcytic.
Iron deficiency, chronic disease and thalassemia traits are the three leading causes of microcytic anemia.
The true cause of... | C15 |
2,664 | 3,374 | A phase I study of a new cisplatin derivative for hematologic malignancies.
DWA2114R (DWA) is a new derivative of platin compounds that is currently being used in Phase II studies of solid tumors in Japan.
The dose-limiting factor is myelotoxicity with mild extramedullary toxicity.
This Phase I study consisted of ad... | C15 |
2,665 | 2,956 | Coexisting thymic carcinoid tumor and thymoma.
Thymic carcinoid tumors are unusual neoplasms that are different from thymomas.
We report a case of coexisting thymic carcinoid tumor and thymoma associated with myasthenia gravis.
The clinicopathological findings are discussed with a review of the literature. | C15 |
2,666 | 6,572 | Hypothermia and acidosis worsen coagulopathy in the patient requiring massive transfusion.
Massive transfusion may cause abnormalities of electrolytes, clotting factors, pH, and temperature and may occur in a scenario of refractory coagulopathy and irreversible shock.
Identification of correctable variables to improv... | C15 |
2,667 | 9,267 | Caesarean section in a patient with haemoglobin SC disease and a phaeochromocytoma.
The anaesthetic management of a patient with haemoglobin SC disease for lower segment Caesarean section and excision of a phaeochromocytoma is described.
The patient was given a general anaesthetic for the surgical procedure after exc... | C15 |
2,668 | 5,511 | Eosinophilia-myalgia syndrome (L-tryptophan-associated neuromyopathy).
Histopathologic study of skeletal muscle biopsy in a patient with eosinophilia-myalgia syndrome following L-tryptophan use showed prominent lymphocytic perineuritis, neuritis, and perimysial fasciitis.
The presence of perineuritis and neuritis pro... | C15 |
2,669 | 826 | Tartrate resistant acid phosphatase positive splenic lymphoma: a relatively benign condition occurring in a time-space cluster?
Conventional light and electron microscopic studies, together with cytochemical and immunocytochemical staining procedures, were carried out to ascertain whether the lymphomata of four elderl... | C15 |
2,670 | 6,413 | Prenatal diagnosis of laryngeal atresia.
In a patient in whom preeclampsia developed at 23 weeks' gestation, ultrasonographic examination of the fetus showed enlarged edematous lungs, a compressed fetal heart, severe ascites, fetal hydrops, and placental edema.
Autopsy of the hydropic stillborn infant showed laryngea... | C15 |
2,671 | 2,527 | Continuing controversy in alloimmune thrombocytopenia: fetal hyperimmunoglobulinemia fails to prevent thrombocytopenia.
Two patients with severe alloimmune thrombocytopenia were managed by weekly intrauterine platelet transfusions at 25 to 36 weeks.
In one patient high-dose immunoglobulin was also administered weekly... | C15 |
2,672 | 4,322 | Hypergammaglobulinemic purpura of Waldenstrom.
Hypergammaglobulinemic purpura of Waldenstrom is characterized by hypergammaglobulinemia, recurring purpura, an elevated erythrocyte sedimentation rate, and the presence of rheumatoid factor indicative of circulating immune complexes.
There is a significant association w... | C15 |
2,673 | 2,536 | Spontaneous infarction of placental chorioangioma and associated regression of hydrops fetalis.
We report a case of a large chorioangioma diagnosed prenatally with concomitant meconium peritonitis and hydrops fetalis in the second trimester.
Spontaneous regression of the tumor occurred, associated with some resolutio... | C15 |
2,674 | 3,247 | Idiopathic thrombocytopenic purpura in pregnancy: a randomized trial on the effect of antenatal low dose corticosteroids on neonatal platelet count
OBJECTIVE--To determine the efficacy of antenatal low dose oral betamethasone in preventing neonatal thrombocytopenia and/or bleeding in infants of mothers with idiopathi... | C15 |
2,675 | 5,951 | Cytomegalovirus infections in bone marrow transplant recipients given intensive cytoreductive therapy.
Cytomegalovirus (CMV) infections were studied in 785 bone marrow transplant recipients given intensive cytoreductive therapy.
CMV excretion occurred in 24%, viremia in 9%, seroconversion in 40%, and overall active i... | C15 |
2,676 | 2,513 | Treatment of the anemia of chronic renal failure with subcutaneous recombinant human erythropoietin.
PURPOSE: The purpose of this study was to determine the efficacy of recombinant human erythropoietin (rHuEPO) given subcutaneously three times/week in patients with chronic renal failure and anemia (predialysis).
PATI... | C15 |
2,677 | 4,348 | Eosinophilic pustular folliculitis: fungal folliculitis?
Eosinophilic pustular folliculitis is a rare condition with no known cause.
However, a fungal cause is suggested by (1) tinea-like annular lesions, (2) initial clinical consideration of fungal folliculitis in many reported cases, (3) an association with the acq... | C15 |
2,678 | 6,481 | Cytokine production (IL-1 alpha, IL-1 beta, and TNF alpha) and endothelial cell activation (ELAM-1 and HLA-DR) in reactive lymphadenitis, Hodgkin's disease, and in non-Hodgkin's lymphomas. An immunocytochemical study.
Cryostat sections of 58 lymph nodes were immunostained with a polyclonal rabbit serum against IL-1 al... | C15 |
2,679 | 4,822 | Mechlorethamine, vincristine, and procarbazine chemotherapy for recurrent high-grade glioma in adults: a phase II study.
We undertook a phase II study of combination chemotherapy with mechlorethamine (nitrogen mustard) 6 mg/m2 intravenously day 1 and day 8, vincristine 2 mg intravenously day 1 and day 8, and procarbaz... | C15 |
2,680 | 7,087 | Analysis of platelet aggregation disorders based on flow cytometric analysis of membrane glycoprotein IIb-IIIa with conformation-specific monoclonal antibodies.
Normal primary platelet aggregation requires agonist-mediated activation of membrane GPIIb-IIIa, binding of fibrinogen to GPIIb-IIIa, and cellular events afte... | C15 |
2,681 | 9,188 | Treatment with 13-cis-retinoic acid in transfusion-dependent patients with myelodysplastic syndrome and decreased toxicity with addition of alpha-tocopherol.
PURPOSE: The purpose of this study was to determine the response and tolerance to long-term treatment using 13-cis-retinoic acid (13-CRA) in transfusion-dependen... | C15 |
2,682 | 76 | A specific in vitro bioassay for measuring erythropoietin levels in human serum and plasma.
The accurate measurement of biologically active erythropoietin (Ep) in human serum and plasma using present in vivo and in vitro bioassays is difficult because of the presence of both inhibitors and non-Ep stimulators of erythr... | C15 |
2,683 | 9,353 | Normal reticulin level in iliac bone marrow.
While the level of marrow reticulin may be a factor that is used when the presence of a hematologic disorder is being considered, to our knowledge no study has graded the amount of reticulin present in normal iliac bone marrow.
Grading reticulin stains of bone biopsy speci... | C15 |
2,684 | 841 | Clinical manifestations in anticardiolipin antibody-positive patients with progressive systemic sclerosis.
Anticardiolipin antibody-positive patients with progressive systemic sclerosis were analyzed.
Elevated anticardiolipin antibody titers were observed in 13 of 40 cases (33%).
Anticardiolipin antibody titer was s... | C15 |
2,685 | 5,937 | Management of the hematologic complications of human immunodeficiency virus infection.
Replication of various strains of human immunodeficiency virus can be increased in vitro by certain colony-stimulating factors (CSFs), but the protective effect of zidovudine (AZT) on macrophages is not antagonized in the presence o... | C15 |
2,686 | 2,176 | Bronchoalveolar lavage findings in a patient with the organic dust toxic syndrome.
A previously healthy student developed the organic dust toxic syndrome after unloading a grain silo for one day.
Bronchoalveolar lavage seven days later showed a total cell count six times normal with 70% lymphocytes.
This suggests th... | C15 |
2,687 | 9,264 | Nitrobenzene poisoning and spurious pulse oximetry.
The successful management of nitrobenzene poisoning in a 21-year-old patient is presented.
We report our experience of ventilatory care with additional intravenous methylene blue and ascorbic acid therapy.
Pulse oximeters available at present are not useful in pati... | C15 |
2,688 | 4,356 | Traumatic asphyxia.
Traumatic asphyxia is a distinctive clinical syndrome characterized by cervicofacial cyanosis and edema, multiple petechiae, and subconjunctival hemorrhage after a severe crush injury of the thorax or of the upper part of the abdomen.
A case of traumatic asphyxia is reported, and its clinical and ... | C15 |
2,689 | 5,192 | Improvement of brain function in hemodialysis patients treated with erythropoietin.
To evaluate the effects of recombinant human erythropoietin (rHuEPO) on brain function, 15 chronic hemodialysis patients were studied by event-related P300, stimulus-related evoked potentials, and trailmaking before (hematocrit 22.7%) ... | C15 |
2,690 | 2,728 | Late chronic hemolysis after valve replacement for aortic stenosis. Relation to residual hypertrophy and impaired left ventricular function.
The relationship between intravascular hemolysis induced by aortic valve prosteses and patient status/left ventricular (LV) function (radionuclide cardiography) was examined in 6... | C15 |
2,691 | 6,067 | The role of gastric resection in the management of multicentric argyrophil gastric carcinoids.
A patient with pernicious anemia, atrophic non-antral gastritis, hypergastrinemia, and widespread hyperplasia of enterochromaffin-like cells and manifest enterochromaffin-like cell carcinoma was followed up during 39 months,... | C15 |
2,692 | 5,630 | Immunoglobulin G subclasses in serum and circulating immune complexes in patients with Kawasaki syndrome.
IgG subclass concentrations in sera of 17 patients with Kawasaki syndrome were determined.
Significantly increased IgG1 (P less than 0.001) and IgG3 (P less than 0.001) were found in the patients compared with 22... | C15 |
2,693 | 4,191 | Aggressive blood conservation in coronary artery surgery: impact on patient care.
Data on 100 consecutive non-emergency coronary artery bypass (CABG) patients were analyzed retrospectively.
Sixty-nine patients received no homologous blood (Group I).
Thirty-one patients received a total of 118 units of blood products... | C15 |
2,694 | 842 | Hypereosinophilic syndrome with unusual cutaneous manifestations in two men with HIV infection.
We report two men with human immunodeficiency virus infection who had unusual cutaneous manifestations of hypereosinophilic syndrome, exfoliative erythroderma, and linear flagellate plaques.
In the first patient the cutane... | C15 |
2,695 | 3,726 | Exercise performance of polycythemic chronic obstructive pulmonary disease patients. Effect of phlebotomies.
The purpose of this study was to determine the effects of phlebotomy on the exercise tolerance and right and left ventricular ejection fraction of polycythemic patients with chronic obstructive pulmonary diseas... | C15 |
2,696 | 3,293 | Deficiency of glycosyl-phosphatidylinositol-linked membrane glycoproteins of leukocytes in paroxysmal nocturnal hemoglobinuria, description of a new diagnostic cytofluorometric assay.
Paroxysmal nocturnal hemoglobinuria (PNH) is a disease that affects not only red cells, but other blood cells as well.
The common defe... | C15 |
2,697 | 8,945 | Effects of the differentiating agent hexamethylene bisacetamide on normal and myelodysplastic hematopoietic progenitors.
Hexamethylene bisacetamide (HMBA; NSC 95580) is a potent polar-planar differentiating agent of leukemia and solid tumor cell lines in vitro at clinically achievable concentrations.
HMBA is currentl... | C15 |
2,698 | 89 | Transfusion and alloimmunization in sickle cell disease. The Cooperative Study of Sickle Cell Disease.
In 1,814 patients with sickle cell disease who had been transfused, the overall rate of alloimmunization to erythrocyte antigens was 18.6%.
The rate of alloimmunization in this group appears to be an explicit functi... | C15 |
2,699 | 5,530 | Doppler umbilical artery studies in the twin-twin transfusion syndrome.
Eleven patients with twin pregnancies were identified as having twin-twin transfusion syndrome on the basis of like-sex twins with monochorionic placentation and umbilical venous blood hemoglobin differences exceeding 50 g/L at delivery.
Umbilica... | C15 |
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