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Neonatal interleukin-1 beta, interleukin-6, and tumor necrosis factor: cord blood levels and cellular production. In a prospective study, levels of interleukin-1 beta (IL-1 beta), interleukin-6) (IL-6), and tumor necrosis factor (TNF) were measured in a blind fashion in cord blood plasma from 92 neonates by specific i...
C01
501
6,858
Myocardial preservation using lidocaine blood cardioplegia. Prevention of ventricular fibrillation after aortic unclamping using lidocaine hydrochloride as an additive to cold potassium blood cardioplegia was studied prospectively in 46 patients undergoing elective myocardial revascularization. Patients were similar ...
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502
684
Monomicrobial nonneutrocytic bacterascites: a variant of spontaneous bacterial peritonitis. Spontaneous bacterial peritonitis is diagnosed when (a) the ascitic fluid culture is positive, (b) the ascitic fluid neutrophil count is greater than or equal to 250 cells/mm3 and (c) there is no evident intraabdominal surgical...
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503
358
Effect of blood transfusion on oxygen consumption in pediatric septic shock. Treatment plans for pediatric septic shock advocate increasing oxygen consumption (VO2). Recent studies in septic shock indicate that improving oxygen delivery (DO2) by increasing blood flow will increase VO2. We prospectively examined the ...
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504
9,939
Septic Streptococcus milleri spondylodiscitis. We describe 2 patients presenting lumbar spondylitis due to Streptococcus milleri. In both cases origin was related to preexistent intestinal pathology. Surgical drainage of a collection of pus was necessary in one case. Longterm antibiotic therapy led to full recovery...
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505
33
Multiple intracranial mucoceles associated with phaeohyphomycosis of the paranasal sinuses. The purpose of this article is to alert clinicians to a new pathogenic fungus of the paranasal sinuses called Exserohilum rostratum. Exserohilum species are one of the etiologic agents of phaeohyphomycosis, a constellation of ...
C01
506
7,524
Vancomycin pharmacokinetics in hydrocephalic shunt prophylaxis and relationship to ventricular volume. Vancomycin pharmacokinetics were determined in 25 patients receiving ventriculoperitoneal shunts for hydrocephalus. Computed tomography scan-derived ventricular-brain ratio as an expression of hydrocephalus varied b...
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507
2,524
Sexually transmitted diseases and human immunodeficiency virus infection among women with pelvic inflammatory disease. Both human immunodeficiency virus infections and pelvic inflammatory diseases are sexually acquired illnesses of great consequence to women. This study was undertaken to determine if women hospitaliz...
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508
4,337
Problems of resistant dermatophytes. Recalcitrant fungal infections are defined as infections that are difficult or impossible to eradicate despite seemingly adequate treatment with appropriate oral or parenteral antibiotics. Relative or absolute microbial resistance is only one of the many causes of recalcitrance. ...
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509
8,305
A general model of sexually transmitted disease epidemiology and its implications for control. Achieving control of STDs may be possible by integrating the activities discussed previously with further research to provide additional empiric data on sex behavior, to develop innovative strategies to access and communicat...
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510
2,274
Disc space infection: a case report with MRI diagnosis. Vertebral disc space infection is an uncommon cause of back pain. Physical findings may be unimpressive and laboratory evaluation may only disclose an elevated erythrocyte sedimentation rate. Magnetic resonance imaging is particularly useful, since it reveals a...
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511
8,311
The "nuisance" sexually transmitted diseases: molluscum contagiosum, scabies, and crab lice. Although molluscum contagiosum, scabies, and infestation by crab lice do not carry the requirements of partner notification or other long-term consequences, they are among the most commonly reported sexually transmitted diseas...
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512
4,985
Gunshot injuries to the hip and abdomen: the association of joint and intra-abdominal visceral injuries. A retrospective review of all gunshot injuries to the hip at our medical center over a 24-year period was performed. Adequate information and radiographs were available for 49 patients. Of these, five patients (1...
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513
8,307
Syphilis in adults. This article reviews the clinical manifestations of syphilis, diagnostic tests that might help to diagnose accurately the disease, and current recommendations for therapy. The association of syphilis and human immunodeficiency virus infection raises additional questions related to transmission, di...
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514
720
Fungal pseudomeningitis superimposed on Escherichia coli meningitis. Pseudomeningitis is the demonstration of microorganisms from the cerebrospinal fluid by stain or culture in a patient with symptoms suggesting meningitis. This is a report of fungal pseudomeningitis superimposed on a case of nosocomial Escherichia c...
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515
5,278
Infective dermatitis of Jamaican children: a marker for HTLV-I infection In Jamaican children infective dermatitis is a chronic eczema associated with refractory nonvirulent Staphylococcus aureus or beta-haemolytic streptococcus infection of the skin and nasal vestibule. 14 children between the ages of 2 and 17 year...
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516
6,904
Management of mycotic rupture of the ascending aorta after heart-lung transplantation. A 19-year-old woman underwent heart-lung transplantation for obstructive bronchiolitis. Eleven days later mycotic rupture of the ascending aorta occurred. Emergency cardiopulmonary bypass was instituted via the femoral vessels and...
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517
3,758
Anti-Kveim monoclonal antibody. New monoclonal antibody reacting to epithelioid cells in sarcoid granulomas. A monoclonal antibody to the sarcoid granulomagenic agent contained in Kveim suspension was prepared by immunizing mice with Kveim suspension. One monoclonal antibody (IHY-1) that reacted with the epithelioid ...
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518
9,133
Sternoclavicular septic arthritis due to haemophilus influenzae. We have reported a case of septic sternoclavicular arthritis illustrating a rare complication of infection with a relatively common pathogen, Haemophilus influenze. Early identification of the infecting organism and appropriate antibiotic therapy are es...
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519
2,518
Evidence of subclinical blastomycosis in forestry workers in northern Minnesota and northern Wisconsin. PURPOSE: To investigate the incidence of remote subclinical blastomycosis in a high-risk population of forestry workers. PATIENTS AND METHODS: The study consisted of 39 male forestry workers from northern Minnesota...
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520
5,389
A newly recognized fastidious gram-negative pathogen as a cause of fever and bacteremia BACKGROUND. We identified a motile, curved, gram-negative bacillus as the cause of persistent fever and bacteremia in two patients with symptomatic human immunodeficiency virus infection. The same organism was subsequently recov...
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521
9,937
Sternocostoclavicular hyperostosis: two cases with differing dermatologic syndromes. Sternocostoclavicular hyperostosis is a rare rheumatic condition characterized by ossification and erosion of the clavicle and the first rib, that has been shown to be associated with pustular skin lesions. We present 2 cases, one of...
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522
5,629
Central nervous system tuberculosis in children: a review of 30 cases. The medical records of 30 children with central nervous system tuberculosis (CNS tuberculosis) who were treated between March, 1976, and February, 1989, were reviewed. All had cranial computerized tomography scans at presentation. The mean cerebr...
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523
5,394
The sequelae of Haemophilus influenzae meningitis in school-age children. BACKGROUND. Previous data on the consequences of Haemophilus influenzae type b meningitis for school-age children have been inconsistent, and much of the information on risk factors has been inconclusive. The present study was designed to eval...
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524
5,550
Pelvic pain and infections. Infectious etiologies of both acute and chronic pelvic pain are common and may involve multiple organ systems. In the evaluation of the acute pain, it is important to remember that rapidity of diagnosis is important because of the possibility of significant morbidity and even death if a co...
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525
5,912
Brucella endocarditis: the role of combined medical and surgical treatment. Brucella endocarditis, although a rare complication of brucellosis, is the main cause of death related to this disease. This report describes a case of aortic endocarditis due to Brucella abortus in an elderly farmer with known aortic stenosi...
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526
7,849
Initial evaluation of human monoclonal anti-lipid A antibody (HA-1A) in patients with sepsis syndrome. HA-1A, a human monoclonal immunoglobulin M antibody that binds specifically to the lipid A domain of endotoxin, was administered to septic patients to evaluate the safety, pharmacokinetics, and immunogenicity of the ...
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527
4,336
History of antifungals. Until two to three decades ago, only a few drugs were available for the treatment of fungal infections. The status of antifungal therapy changed dramatically in the late 1960s with the introduction of newer broader spectrum agents, such as the iodinated trichlorophenols and the imidazoles, tha...
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528
6,811
Iatrogenic contamination of multidose vials in simulated use. A reassessment of current patient injection technique. An investigation of the potential spread of iatrogenic infections through contaminated multidose vials was performed. Contamination of a multidose vial was hypothesized to occur after a single syringe ...
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529
2,541
Postpartum osteomyelitis caused by group B streptococcus. Postpartum infections caused by group B streptococci are generally limited in scope. We report a case of vaginal colonization with group B streptococcus that progressed in the postpartum period to osteomyelitis that necessitated total hip replacement. The pat...
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530
4,342
Treatment of tinea cruris with topical terbinafine. Twenty-three patients were enrolled in a randomized, double-blind trial of terbinafine 1% cream versus its vehicle (placebo) in the treatment of tinea cruris. One patient had a negative initial culture and was excluded, and two patients were dropouts, one because of...
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531
5,626
Nosocomial bacteremias in measles. The purpose of this study was to determine whether nosocomial bacteremias occurred more frequently in patients admitted with severe measles compared with general pediatric admissions. In a retrospective survey of 977 blood culture reports during a 4-year period, 1985 to 1988, the in...
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532
2,447
Disseminated, nonmeningeal gastrointestinal cryptococcal infection in an HIV-negative patient. Gastrointestinal cryptococcosis is extremely rare, especially in patients with no involvement of the central nervous system. We describe a 63-yr-old man undergoing prednisone therapy for chronic hepatitis and cirrhosis who ...
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533
5,254
Person-to-person transmission of Pseudomonas cepacia between patients with cystic fibrosis. Ribotyping, a method of strain identification based on analysis of bacterial genomic restriction fragment length polymorphisms, was used to investigate the acquisition of Pseudomonas cepacia by a patient with cystic fibrosis. ...
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534
5,466
Infectious intracranial aneurysms: comparison of groups with and without endocarditis. A series of 12 patients with infectious intracranial aneurysms is presented, and a number of unusual features of the disorder are emphasized. A comparison of characteristics of the aneurysms and clinical course is made between pati...
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535
7,642
Ocular atopy and mycotic keratitis. In a retrospective analysis, we studied the association between ocular atopy and keratomycosis. Forty-one (26.3%) of 156 patients with fungal corneal ulcers were found to have preexisting allergic conjunctivitis. All patients had been using a combination of antibiotics and cortico...
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536
6,906
Left recurrent laryngeal nerve paralysis: an unusual presentation of histoplasmosis. A case of histoplasmosis seen as left recurrent laryngeal nerve paralysis in a 49-year-old man is described. The patient had roentgenographic findings of a solitary, noncalcified left upper lobe mass and mediastinal adenopathy. Tiss...
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537
4,353
Miliary tuberculosis presenting as skin lesions in a patient with acquired immunodeficiency syndrome. Acute miliary tuberculosis of the skin is an extremely rare infection that occurs in immunocompromised persons. We report an intravenous drug abuser with human immunodeficiency virus infection in whom erythematous pa...
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538
5,156
Association of group C beta-hemolytic streptococci with endemic pharyngitis among college students Throat cultures were performed throughout 2 school years to determine whether non-group A beta-hemolytic streptococci (NGA BHS) could be isolated more frequently in 232 college students who had symptomatic pharyngitis t...
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539
352
Sepsis-related cardiogenic shock. To further define cardiovascular abnormalities in patients with septic shock, serial conventional hemodynamic measurements combined with two-dimensional echocardiographic studies were performed at the bedside in 21 patients admitted for an acute episode of sepsis-related circulatory f...
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540
2,263
Pleuropulmonary manifestations of hepatic amebiasis Pleuropulmonary manifestations of hepatic amebiasis occurred in 30 patients; 18 (60%) presented with at least 1 pulmonary complaint and 10 (33%) had multiple pulmonary symptoms. In 14 patients (47%), abnormalities were found on examination of the chest. In 16 ches...
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541
6,884
Treatment of postoperative infection of ascending aorta and transverse aortic arch, including use of viable omentum and muscle flaps. Postoperative infection of the ascending aorta and aortic arch in 40 patients was treated by antibiotic therapy alone (4 patients) or by operation and lifelong suppressive antibiotic th...
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542
3,029
Immediate breast reconstruction following mastectomy is as safe as mastectomy alone. We evaluated wound complications and potential risk factors after mastectomy with immediate breast reconstruction and compared them with similar data after modified radical mastectomy. The incidences of infection, seroma, hematoma, a...
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543
9,196
Determinants of condom use among French heterosexuals with multiple partners. In September 1988, a sample of French individuals between 18 and 49 years of age, who reported more than one sexual partner in the past six months and who considered themselves heterosexuals (n = 1088), were interviewed at home about risk pe...
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544
7,898
Pseudomonas aeruginosa compared with Escherichia coli produces less endotoxemia but more cardiovascular dysfunction and mortality in a canine model of septic shock. We investigated the effects of two different Gram-negative bacteria and radiation-induced leukopenia on endotoxemia, cardiovascular abnormalities, and mor...
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545
741
External fixation for type III open tibial fractures. An analysis of 51 type III open tibial fractures treated by external skeletal fixation is presented. The fractures are subdivided according to the classification of Gustilo, Mendoza and Williams (1984) into types IIIa, IIIb and IIIc. The different prognoses of th...
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546
4,636
Coccidioidomycosis in human immunodeficiency virus-infected patients. Coccidioidomycosis is at best a complicated fungal infection; often it is life-threatening. Coccidioidomycosis is confined epidemiologically to the southwestern region of the USA, and most cases have occurred in that area, particularly in Arizona. ...
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547
4,626
Properties of strains of Escherichia coli O26:H11 in relation to their enteropathogenic or enterohemorrhagic classification. Thirty-seven strains of Escherichia coli O26:H11 from infants and calves with diarrhea were examined for properties associated with enteropathogenic (EPEC) or enterohemorrhagic E. coli (EHEC). ...
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548
4,462
Bioaerosols: prevalence and health effects in the indoor environment. Assessing the role of bioaerosols in residence-related symptoms involves (1) determining that symptoms are related to the residence by medical examination and careful questioning, (2) connecting reported symptoms with known or hypothesized effects o...
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549
876
Itraconazole in tinea versicolor: a review. Itraconazole, a new orally active triazole antifungal, has been tested in patients with pityriasis versicolor. A number of studies have shown that itraconazole is effective for this mild fungal skin disease. The total dose required for effective treatment is 1000 mg, and i...
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550
4,631
Antimicrobial resistance of Shigella isolates in the USA: the importance of international travelers. A nationwide sample of Shigella isolates was collected and tested for resistance to 12 antimicrobial agents to assess the prevalence and epidemiologic correlates of antimicrobial resistance in Shigella. Of the isolate...
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551
5,633
Safety evaluation of PRP-D Haemophilus influenzae type b conjugate vaccine in children immunized at 18 months of age and older: follow-up study of 30,000 children. We evaluated the safety of the PRP-D conjugate Hib vaccine (ProHIBit, Connaught) in 29,309 children vaccinated at 18-60 months of age in the Southern Calif...
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552
5,650
Dexamethasone effects on the hospital course of infants with bronchopulmonary dysplasia who are dependent on artificial ventilation. A randomized double-blind placebo-controlled trial was conducted to evaluate the effects of enterally administered dexamethasone on the hospital course of infants with bronchopulmonary d...
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553
4,031
Infection control in the nursing home: the physician's role. Infection control in the nursing home or long-term care facility is an increasingly complex activity. The high rates (approximately 15%) and special risks (group activities, crowding) for nosocomial infection demand special attention by attending physicians...
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554
4,348
Eosinophilic pustular folliculitis: fungal folliculitis? Eosinophilic pustular folliculitis is a rare condition with no known cause. However, a fungal cause is suggested by (1) tinea-like annular lesions, (2) initial clinical consideration of fungal folliculitis in many reported cases, (3) an association with the acq...
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555
847
Skin pigmentation from clofazimine therapy in leprosy patients: a reappraisal. Skin biopsy specimens from two lepromatous leprosy patients with dark brown pigmentation who were receiving long-term clofazimine therapy were studied. Ceroid-lipofuscin pigment was demonstrated inside macrophages that contained numerous p...
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556
7,592
Impetigo. Current etiology and comparison of penicillin, erythromycin, and cephalexin therapies. We attempted to determine the causative bacterial pathogens of impetigo in children in our area, to compare the effectiveness of three frequently used oral antimicrobial treatment regimens, and to correlate the antimicrobi...
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557
418
Effects of epinephrine on hemodynamics and oxygen metabolism in dopamine-resistant septic shock. The hemodynamic effects of epinephrine were prospectively studied in 13 patients with septic shock who remained hypotensive after both fluid loading and dopamine. Hemodynamic measurements were performed before and one hou...
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558
4,670
Transmission of Chlamydia pneumoniae in young children in a Japanese family. Chlamydia pneumoniae strain TWAR was isolated from the respiratory tract of a 5-year-old girl suffering from pneumonia. The IgM and IgG antibody titers to TWAR were 1:32 and 1:128, respectively. Cultures and serology for other common bacter...
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559
880
Treatment of oral candidosis with itraconazole: a review. Oral candidosis is a common infection in infants, elderly persons, patients receiving immunosuppressive therapy, and patients with acquired immunodeficiency syndrome (AIDS). The orally active antifungal agent itraconazole has been evaluated in a number of diff...
C01
560
6,354
Adult and pediatric peritonitis rates in a home dialysis program: comparison of continuous ambulatory and continuous cycling peritoneal dialysis. We reviewed our 115-month experience with continuous ambulatory peritoneal dialysis (CAPD) and continuous cycling peritoneal dialysis (CCPD) in adult and pediatric patients ...
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561
434
Short-term chemoprophylaxis with ceftizoxime vs. five-day aminoglycoside with metronidazole in 'contaminated' lower gastrointestinal surgery. In a prospective, open, randomized controlled trial, 173 patients requiring surgery for potentially "contaminated" lower gastrointestinal surgery were allocated to receive eithe...
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562
7,850
Dependence of oxygen consumption on oxygen delivery in children with hyperdynamic septic shock and low oxygen extraction. We studied the effect of increasing systemic oxygen delivery (DO2) by packed RBC (PRBC) transfusion on oxygen consumption (VO2) in children with hyperdynamic septic shock. After routine resuscitat...
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563
6,983
Antibiotic pharmacokinetics in surgery Pharmacokinetics is the study of variables that affect drug concentrations at the effector site. The descriptive terms peak concentration, elimination half-life, volume of distribution, and bioavailability are commonly used to express pharmacokinetic variability among drugs use...
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564
3,724
Pulmonary manifestations of disseminated cryptococcosis in patients with AIDS. Forty-eight patients with disseminated cryptococcosis and AIDS were retrospectively studied to define the pulmonary manifestations. Cryptococcus neoformans (CN) was first isolated from a pulmonary site in 12 patients. Disseminated disease...
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565
9,254
Outpatient percutaneous central venous access in cancer patients. A 1-year experience of percutaneous subclavian catheterization in outpatients with cancer was reviewed to document reliability, safety, and cost. There were 763 catheter insertions attempted with prospective documentation of complications in 664 consec...
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566
6,026
Pleuropulmonary tularemia: successful treatment with erythromycin. A 64-year-old man had community-acquired pneumonia that was retrospectively diagnosed as pleuropulmonary tularemia. He was successfully treated with erythromycin. We review the case and briefly discuss the literature on this point.
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567
569
A small animal model of human Helicobacter pylori active chronic gastritis. Isolation of a spiral-shaped bacterium closely related to Helicobacter pylori from the cat stomach made it possible to investigate new small animal models of gastric infection. Pure cultures of this bacterium, provisionally named "Helicobacte...
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568
4,632
Cefuroxime treatment failure of nontypable Haemophilus influenzae meningitis associated with alteration of penicillin-binding proteins. A 10-year-old boy presented with nuchal rigidity and cerebrospinal fluid (CSF) leukocytosis initially and again on day 6 of intravenous cefuroxime therapy (200 mg/kg/day). Both CSF s...
C01
569
8,843
Thoracic empyema: causes, diagnosis, and treatment. Thoracic empyema is a disease that has been recognized for centuries. The principles of management as stated by Hippocrates remain more or less unchanged. Diagnosis can be masked by the underlying cause, preemptive antibiotic treatment, or the now frequently associ...
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570
9,927
Pyogenic sacroiliitis in a rural population. We describe 10 cases of pyogenic sacroiliitis occurring in a rural population. Seven were male and 3 were female with a mean age of 22.4 years. None was a recent intravenous drug abuser. Five patients had a history of recent pelvic trauma. 99mTechnetium scintiscans reve...
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571
756
Denatured muscle grafts for nerve repair. An experimental model of nerve damage in leprosy About 20% of patients with leprosy develop localised granulomatous lesions in peripheral nerves. We report experiments in guinea-pigs in which freeze-thawed autogenous muscle grafts were used for the treatment of such mycobact...
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572
2,138
Ascending cholangitis: surgery versus endoscopic or percutaneous drainage. A retrospective review of 61 patients with calculous cholangitis was carried out. There were 31 men and 30 women and their mean age was 75.8 years. All patients had abdominal pain, 87% had chills and fever, 65% had clinical jaundice, 23% were...
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573
969
Possible role of leukotrienes in gastritis associated with Campylobacter pylori. This study was done to evaluate the role of leukotrienes (LTs) in gastritis associated with Campylobacter pylori. Biopsy specimens of gastric mucosa were obtained endoscopically from 18 patients with nonulcer dyspepsia for bacteriologica...
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574
8,317
Pelvic inflammatory disease. The costs of PID to both individuals and society are enormous. Although primary prevention of PID through control of lower genital tract infections is the most effective prevention strategy, early diagnosis and treatment of acute PID may minimize some of its serious sequelae. Although la...
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575
5,262
Changing epidemiology of group A streptococcal infection in the USA. To see whether changes in the epidemiology of group A streptococcal disease in the USA have been accompanied by a corresponding change in serotype distribution, epidemiological and M-typing and T-typing data for 5193 strains sent to the Centers for D...
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576
4,704
Rhinosporidiosis associated with squamous cell carcinoma in the tongue. The peritumoural region of a squamous cell carcinoma of the tongue when examined with light and electron microscope showed nodular bodies in the submucosa with all the distinctive features of 'sporangium and 'spores' of rhinosporidiosis. The occu...
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577
9,424
Patterns of bacterial infection in calves implanted with artificial hearts. Device-related infection is one of the most serious potential consequences of total artificial heart (TAH) implantation. This complication must be addressed before the full potential benefit of these devices, especially fully implantable devi...
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578
8,308
Chancroid and the role of genital ulcer disease in the spread of human retroviruses. Chancroid is the most prevalent form of genital ulcer disease in developing countries and is undergoing a resurgence in industrialized countries. As a result of a nonspecificity of the clinical findings, the etiologic diagnosis of ge...
C01
579
6,498
Epidemiologic differences between chlamydia and gonorrhea. To assess the prevalence, demographics, and transmission patterns of genital chlamydia infection, we screened 3,078 patients, and compared identified cases (N = 511) to gonorrhea cases (N = 291) diagnosed in the same setting. Chlamydia cases were younger and ...
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580
5,928
Group C streptococcal arthritis: case report and review. Streptococci account for approximately 15%-20% of cases of nongonococcal septic arthritis. The majority of these are due to group A streptococci, but group B and group G streptococci are being isolated more frequently. We present a case of group C streptococca...
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581
4,673
Nasal carriage of Staphylococcus aureus: correlation with hormonal status in women. In view of recent observations on hormone-microorganism interactions, a study of Staphylococcus aureus nasal carriage in relation to sex-hormone status was undertaken. Prospectively in 479 women attending a colpocytologic clinic, horm...
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582
5,378
Limited efficacy of a Haemophilus influenzae type b conjugate vaccine in Alaska Native infants. The Alaska H. influenzae Vaccine Study Group BACKGROUND. The prevention of invasive Haemophilus influenzae type b disease requires a vaccine that is effective when administered during the first six months of life. The in...
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583
7,834
Newer concepts in antimicrobial therapy. Advances in the treatment of infection have continued to increase both the length and quality of life. Unfortunately, many bacteria can readily adapt to their environment and develop a tolerance to the antimicrobial agents in widespread use. During the recent past, the consum...
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584
4,662
Prevalence and diagnosis of Legionella pneumonia: a 3-year prospective study with emphasis on application of urinary antigen detection. During a 3-year period the frequency of legionellosis in hospitalized patients with community-acquired and nosocomial pneumonias was 3.4% (23/684 cases) and 5.9% (33/559), respectivel...
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585
8,147
Clinically inapparent (asymptomatic) bacteriuria in ambulatory elderly men: epidemiological, clinical, and microbiological findings. In a prospective longitudinal study, ambulatory elderly men were followed from 1 to 4.5 years to gain insight into the prevalence rates, clinical characteristics, and patterns of clinica...
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586
6,018
Neurologic abnormalities in a patient with human ehrlichiosis. Human ehrlichiosis is a tick-borne rickettsial disease characterized by fever, headache, myalgias, anorexia, and occasionally rash. In our patient, changes in mental status, upper motor neuron signs, cerebrospinal fluid pleocytosis, and increased serum pr...
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587
4,667
Confocal microscopic detection of human immunodeficiency virus RNA-producing cells. A central anomaly in the pathogenesis of AIDS is that few actively infected CD4+ cells (1 in 10(4)-10(5) have been detected in the peripheral blood, even though dramatic depletion (often greater than 90%) of CD4+ cells is the hallmark ...
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588
5,916
Pulmonary and disseminated infection due to Mycobacterium kansasii: a decade of experience. Fifty-five patients with Mycobacterium kansasii isolates (47 pulmonary and eight disseminated) were identified at a large Texas hospital from 1975 to 1985. The mean age of patients was 60 years, and there was a slight male pre...
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589
7,897
Prostacyclin but not phentolamine increases oxygen consumption and skin microvascular blood flow in patients with sepsis and respiratory failure. Inadequate tissue oxygenation may occur in critically ill patients with sepsis despite an apparently adequate O2 transport (QO2), and this may contribute to the development ...
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590
9,373
Acquired childhood aphasia. Outcome 1 year after onset. The effects of the variables age at onset, cause, severity and bilaterality of lesion, and type of aphasia on course and outcome were investigated in a group of 28 aphasic children. Analysis of spontaneous speech and tests of auditory verbal comprehension were u...
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591
7,910
Management of Brucella endocarditis with aortic root abscess. Three cases of Brucella endocarditis with aortic root abscess are reported. Two patients were successfully managed by a combination of medical therapy and surgery. The third patient died suddenly 36 hours after admission to hospital.
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592
6,325
Percutaneous central venous catheterization. Three years' experience in a neonatal intensive care unit. Prolonged venous access is desirable in very-low-birth-weight infants and infants for whom feedings are contraindicated. We prospectively evaluated 481 small-diameter venous catheters placed percutaneously in 317 p...
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593
8,326
Bird attack on milk bottles: possible mode of transmission of Campylobacter jejuni to man A case-control study was carried out to test the hypothesis that the rise in the rate of Campylobacter jejuni infection in the Brigend area of South Wales during May was due to the consumption or handling of milk from bottles th...
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594
6,931
Recurrent meningitis in a patient with congenital deficiency of the C9 component of complement. First case of C9 deficiency in Europe. We describe the first cases, to our knowledge, of C9 deficiency in Europe that were detected in a Swiss family, of which two members--one with a complete deficiency and the other with ...
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595
9,185
Ofloxacin treatment of Chlamydia pneumoniae (strain TWAR) lower respiratory tract infections. PURPOSE: Limited data suggest that tetracycline or erythromycin is the antibiotic of choice for treating Chlamydia pneumoniae infection, but they are not always effective or well tolerated. Because the fluoroquinolone ofloxa...
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596
2,872
Activities of clarithromycin, sulfisoxazole, and rifabutin against Mycobacterium avium complex multiplication within human macrophages. The activities of clarithromycin, sulfisoxazole, and rifabutin against three virulent strains of Mycobacterium avium complex isolated from patients with acquired immunodeficiency synd...
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597
4,198
An unusual late complication following surgical repair of tetralogy of Fallot. A case is presented of extrusion of right ventricular outflow tract patch material through a mediastino-cutaneous fistula occurring five years after repair of tetralogy of Fallot. The focus of the mediastinal infection was an infected epic...
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598
7,548
High-dose phenylephrine infusion in the hemodynamic support of septic shock. A 75-year-old man with hyperdynamic septic shock and vasodilation was successfully supported hemodynamically for 88.5 hours through the use of a continuous infusion of phenylephrine at dosages up to 360 micrograms/min. The only other vasoact...
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599
4,671
Pilot trial of selective decontamination for prevention of bacterial infection in an intensive care unit. Selective decontamination of the oropharynx and gastrointestinal tract with nonabsorbable antimicrobials and sucralfate, a stress ulcer prophylactic that maintains the normal gastric acid bacterial barrier, were c...
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