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8,200 | 7,771 | Diffuse sclerosing variant of papillary carcinoma of the thyroid. Clinical importance, surgical treatment, and follow-up study.
A diffuse sclerosing variant is not very rare among papillary carcinomas of the thyroid when the patients are female and younger than 30 years of age.
The variant is characterized by diffuse... | C04 |
8,201 | 2,074 | Malignant melanoma and pigmented lesions: a diagnostic and management dilemma.
We document two cases of malignancy occurring at the site of partially removed benign nevi.
Because of the difficulty in clinical diagnosis and the uncertainty in its behavior, we propose that any recurring melanocytic nevus expanding beyo... | C04 |
8,202 | 7,769 | Comparison of lymphangiography and computed tomography scanning in evaluating abdominal disease in stages III and IV Hodgkin's disease. A Southwest Oncology Group study.
The authors reviewed the records of 139 patients who had laparotomy plus computed tomography (CT) and/or lymphangiograms (LAG) as part of a their sta... | C04 |
8,203 | 4,976 | Oral zidovudine, continuous-infusion fluorouracil, and oral leucovorin calcium: a phase I study.
A phase I clinical, pharmacologic, and biochemical evaluation of escalating oral zidovudine (AZT) given over 2 days with a fixed dose of continuous-infusion fluorouracil (800 mg/m2 per day X 3 days) and oral leucovorin cal... | C04 |
8,204 | 3,026 | Is liver transplantation justified for the treatment of hepatic malignancies?
Twenty-eight patients received orthotopic liver transplants for malignant disease between February 1, 1984, and December 31, 1989.
Preoperative diagnoses included hepatocellular carcinoma (n = 16), cholangiocarcinoma (n = 3), other primary ... | C04 |
8,205 | 2,656 | Sequential connection of flaps: a logical approach to customized mandibular reconstruction.
Microsurgery has improved the success rate for reconstruction of composite defects in the head and neck.
Restoration of mandibular continuity alone is not adequate for reconstruction.
Replacement of the oral lining with thin ... | C04 |
8,206 | 8,128 | Congenital midline nasal masses: diagnosis and management.
Congenital midline nasal masses (CMNMs) are rare lesions most commonly caused by dermoids, hemangiomas, nasal gliomas or encephaloceles.
We report a case of nasal glioma and discuss the embryologic development, evaluation, and management of such CMNMs. | C04 |
8,207 | 7,651 | Effect of bleomycin on hematoporphyrin derivative phototherapy of solid tumors.
Hematoporphyrin derivative phototherapy (HpD-PT) has been successfully used to localize and treat superficial squamous cell cancers.
Bleomycin sulfate is a glycopeptide antibiotic that has antineoplastic properties against squamous cell c... | C04 |
8,208 | 7,049 | Photodynamic therapy in the treatment of squamous cell carcinoma of the head and neck.
Photodynamic therapy is an experimental modality for tumor treatment based on the combined action of the tumor-localizing agent, ie, hematoporphyrin derivative, and red light.
From 1985 through 1989, 26 patients were treated using ... | C04 |
8,209 | 3,284 | Human macrophage colony-stimulating factor induces macrophage colonies after L-phenylalanine methylester treatment of human marrow.
Macrophage-colony stimulating factor (M-CSF) has well-known effects on murine bone marrow, but its colony stimulating activity for human bone marrow is controversial.
After treatment of ... | C04 |
8,210 | 2,663 | Serologic determinants of survival in patients with squamous cell carcinoma of the head and neck.
Specific circulating serum proteins may reflect unique properties governing the growth and progression of head and neck cancers.
One hundred three previously untreated patients with squamous cell carcinoma of the head an... | C04 |
8,211 | 7,476 | Hilar malignancy: treatment with an expandable metallic transhepatic biliary stent.
An expandable metallic transhepatic biliary endoprosthesis was used to treat 20 patients with hilar malignancy and isolated right and left intrahepatic ducts.
In 12 patients, only one intrahepatic ductal system was drained; in eight p... | C04 |
8,212 | 9,724 | Squamous carcinoma in the liver.
Squamous carcinoma of the liver has only rarely been reported.
We present a case which highlights not only the difficulties in diagnosis but also how it can closely mimic sclerosing cholangitis. | C04 |
8,213 | 9,829 | Causes of death in the elderly and their changing pattern in Hisayama, a Japanese community. Results from a long-term and autopsy-based study.
The causes of death for the elderly were prospectively studied in Hisayama, Japan, a rural community.
We compared 1,621 subjects, aged 40 years or over, recruited in 1961, and... | C04 |
8,214 | 5,477 | Concurrent intradural and extradural meningiomas of the cervical spine.
A case of an extradural spinal meningioma presenting with a separate intradural meningioma at the same cord level is reported.
Review of the English literature on spinal epidural meningiomas reveals a high incidence of concurrent intradural tumor... | C04 |
8,215 | 9,306 | The ras oncogenes in human lung cancer.
The three well-characterized genes of the ras gene family H-ras, K-ras, and N-ras, code for closely related 21-kD proteins that have a role in the transduction of growth signals.
The ras proteins acquire transforming potential when a point mutation in the gene leads to replacem... | C04 |
8,216 | 8,954 | Carcinoid tumors.
The authors carried out a retrospective study of 32 patients (23 M, 9 F) with carcinoid tumors who were diagnosed and treated at Harlem Hospital Center, New York, from 1967 to 1988.
All the patients were black and the commonest sites were the ileum (28.1%), rectosigmoid and rectum (21.9%), and the a... | C04 |
8,217 | 5,424 | Circulating CD8+ cytotoxic T lymphocytes specific for HTLV-I pX in patients with HTLV-I associated neurological disease.
The human T-lymphotropic virus type I (HTLV-I), the first human retrovirus to be characterized, is associated with adult T-cell leukaemia and a chronic progressive disease of the central nervous sys... | C04 |
8,218 | 2,974 | Morbidity, mortality, and quality of life for patients treated with levothyroxine
In a population study of 1462 middle-aged women initiated in 1968 and 1969 we identified 29 women treated with levothyroxine from 1 to 28 years.
In a 12-year follow-up in 1980 and 1981 we investigated the subjects for end-point myocard... | C04 |
8,219 | 424 | Preoperative radiotherapy in operable rectal cancer.
The effect of preoperative radiotherapy (31.5 Gy in 3.5 weeks) in operable rectal cancer was examined with respect to resectability and prognosis after two surgical procedures, abdominoperineal resection, or low anterior resection.
Preoperative radiation did not in... | C04 |
8,220 | 3,801 | Cholecystokinin stimulates growth of human pancreatic adenocarcinoma SW-1990.
The effect of a synthetic analogue of CCK (Thr4,Nle7CCK-9) on growth of SW-1990 human pancreatic cancer was examined in two experimental models.
Nude mice bearing SW-1990 pancreatic cancer xenografts were injected with CCK (5, 15, or 25 mic... | C04 |
8,221 | 7,580 | Secondary T-cell lymphoproliferation after marrow transplantation.
Secondary lymphoproliferative syndromes in immunosuppressed patients have been characterized as polyclonal or monoclonal B-lineage disorders nearly always associated with Epstein-Barr virus (EBV) infection.
The authors now report three patients with a... | C04 |
8,222 | 7,067 | Reliability of colposcopy and directed punch biopsy
A group of 118 women underwent laser cone biopsy.
Data were collected routinely on proforma case notes and entered into a computerized database.
The histology of the cone biopsies was compared with that of previous, colposcopically directed punch biopsies, with th... | C04 |
8,223 | 9,180 | Synchronous diffuse well-differentiated lymphocytic lymphoma and gastric adenocarcinoma presenting as splenomegaly and iron deficiency anemia.
Diffuse well-differentiated lymphocytic lymphoma (D-WDLL) and chronic lymphocytic lymphoma (CLL) represent closely related neoplasms which may have indolent courses.
Dating ba... | C04 |
8,224 | 5,510 | Cavernous hemangioma of the spinal cord: report of 2 unusual cases.
We present 2 cases of spinal cord intramedullary cavernous hemangioma; 1 patient is the 1st reported case of multiple spinal cord lesions.
Diagnosis is greatly enhanced by the use of MRI. | C04 |
8,225 | 5,110 | Gonadoblastoma in an anatomically normal man: a case report and literature review.
Gonadoblastoma, a rare gonadal neoplasm, presents most frequently in phenotypic female or phenotypically male patients with dysgenetic gonads or undescended testes.
To date, only 2 cases of gonadoblastoma have been reported in anatomic... | C04 |
8,226 | 9,124 | Head and neck paragangliomas: a clinicopathologic study with DNA flow cytometric analysis.
A total of 11 head and neck paragangliomas were the subject of pathologic study, including histologic, immunohistochemical, and DNA flow cytometric analyses.
We cannot absolutely predict aggressive clinical behavior using histo... | C04 |
8,227 | 4,228 | Insulin-like growth factor-I receptors in nonfunctioning thyroid nodules.
We have recently demonstrated the production of insulin-like growth factor-I (IGF-I) as well as the presence of type I IGF receptors in human thyroid cells in primary culture.
The role of IGF-I in the control of thyroid cell growth has been wel... | C04 |
8,228 | 207 | Teniposide (VM-26) and continuous infusion cytosine arabinoside for initial induction failure in childhood acute lymphoblastic leukemia. A Pediatric Oncology Group pilot study.
Twenty-six evaluable children with newly diagnosed acute lymphoblastic leukemia (ALL) who failed to achieve initial remission after receiving ... | C04 |
8,229 | 3,796 | Early gastric cancer. Endoscopic diagnosis of depth of invasion.
In order to decide on a treatment strategy against gastric cancers, an accurate preoperative evaluation of the depth of cancer invasion is essential.
Preoperative endoscopic diagnosis of the depth of invasion was compared with pathological results of th... | C04 |
8,230 | 6,912 | Systemic therapy in metastatic colorectal cancer.
Fluorouracil-based chemotherapy regimens have been utilized in metastatic colorectal cancer for more than 30 years.
Early attempts at defining an optimal treatment schedule and use in combination with other drugs failed to significantly improve results.
In contrast, ... | C04 |
8,231 | 5,243 | Parathyroid hormone-related peptide in plasma of patients with hypercalcemia and malignant lesions
We developed and validated a radioimmunoassay for circulating human parathyroid hormone-related peptide (PTHrP), based on a commercial antiserum to the synthetic 1-34 fragment of PTHrP, 125I-Tyr degrees-PTHrP(1-34) as r... | C04 |
8,232 | 7,791 | Simultaneous hepatoblastoma in identical male twins.
Identical male twin infants who in 1987 presented with hepatoblastoma at the age of 7 months are reported.
Twin B was admitted for investigation due to enlarged liver and spleen.
He was found to have an inoperable hepatoblastoma of fetal type and was treated with ... | C04 |
8,233 | 4,971 | Race, nutritional status, and survival from breast cancer.
The effects of nutritional status on differences in the survival of black and white women with breast cancer were studied in a cohort of 1,960 Georgia women diagnosed during 1975-1979.
After data were adjusted for stage of disease, socioeconomic status, and o... | C04 |
8,234 | 5,223 | Ampullary carcinoma in patients under 50 years of age with a poor prognosis.
Clinicopathologic features of 145 Japanese patients with ampullary carcinoma were compared among three age groups.
The 145 patients were divided into three groups by the patient's age at the time of operation; there were 24 patients in group... | C04 |
8,235 | 8,951 | Gamma-detecting probe and autoradiographic studies of radiolabeled antibody B72.3 in CX-1 colon xenografts.
Nude mice bearing CX-1 colon tumors were injected with 50 microCi 125I-labeled monoclonal antibody (MAb) B72.3.
Radioactivity in tumors was studied with the gamma detecting probe (GDP) on days 1, 3, 7, and 10 a... | C04 |
8,236 | 7,389 | Immunoblastic T-cell lymphoma presenting as an eyelid tumor.
A 59-year-old white man presented with an ulcerating mass of the left upper eyelid of 6 months' duration.
A biopsy specimen of the tumor was diagnosed as an immunoblastic T-cell malignant lymphoma.
The lesion completely regressed after 4000 cGy of cobalt-6... | C04 |
8,237 | 9,357 | Lack of prognostic value of nucleolar organizer region enumeration in transitional cell carcinoma of the bladder.
Enumeration of silver-stained nucleolar organizer regions is of limited use in grading transitional cell tumors of the bladder.
We attempted in this article to establish whether or not such a technique wo... | C04 |
8,238 | 8,017 | Expression of class II molecules on intestinal epithelial cells in humans. Differences between normal and inflammatory bowel disease.
Expression of class II antigens on human intestinal epithelial cells was assessed using a sensitive avidinbiotin-peroxidase technique.
HLA-DR was present predominantly in the normal sm... | C04 |
8,239 | 8,944 | Lipolytic factors associated with murine and human cancer cachexia.
We have identified a lipolytic factor in extracts of a cachexia-inducing murine carcinoma (MAC16) that shows characteristics of an acidic peptide and appears to be composed of three fractions of apparent molecular weights corresponding to 3 kd, 1.5 kd... | C04 |
8,240 | 4,823 | Phase II study of fluorouracil and recombinant interferon alfa-2a in previously untreated advanced colorectal carcinoma.
We conducted a phase II clinical trial of fluorouracil (5FU) and recombinant interferon alfa-2a (rIFN alpha-2a) in 52 previously untreated patients with bidimensionally measurable metastatic colorec... | C04 |
8,241 | 3,381 | Structural and ultrastructural study of the ovary in childhood leukemia after successful treatment.
Ovarian biopsy specimens from ten girls (three postmenarcheal) who had undergone antiblastic treatment for acute lymphoblastic leukemia (ALL) and were in complete remission were examined by light microscope.
The biopsy... | C04 |
8,242 | 4,891 | Effects of energy restriction on mouse mammary tumor virus mRNA levels in mammary glands and uterus and on uterine endometrial hyperplasia and pituitary histology in C3H/SHN F1 mice.
We investigated the effects of energy restriction on the pituitary-ovarian axis and on a hormone responsive gene, the mouse mammary tumo... | C04 |
8,243 | 4,836 | Motility factor produced by malignant glioma cells: role in tumor invasion.
To better understand the cellular mechanism of tumor invasion, the production of a cell motility-stimulating factor by malignant glioma cells was studied in vitro.
Serum-free conditioned media from cultures of rat C6 and human T98G cell lines... | C04 |
8,244 | 4,981 | Nonrandom chromosomal abnormalities in primary uveal melanoma.
We report on 14 cases of clonal chromosomal anomalies in patients with primary uveal melanoma.
An increased dosage of chromosome 8 or of parts of the long arm of chromosome 8 (8q) were detected in eight patients (57%).
The smallest multiplied area of 8q ... | C04 |
8,245 | 2,899 | Compound blue nevus: a variant of blue nevus with an additional junctional dendritic component. A clinical, histopathologic, and immunohistochemical study of six cases.
We studied six cases of heavily pigmented melanocytic lesions with features of blue nevi within the dermis, but with an additional junctional dendriti... | C04 |
8,246 | 3,338 | Blood transfusion and recurrence of colorectal cancer: the role of platelet derived growth factors.
Efforts to explain the possible effects of blood transfusion on the recurrence of colorectal cancer have been based entirely on the immunosuppressive effects of blood transfusion.
However, the relationship between soli... | C04 |
8,247 | 8,681 | Intraoperative radiation of canine carotid artery, internal jugular vein, and vagus nerve. Therapeutic applications in the management of advanced head and neck cancers.
As a step in the application of intraoperative radiotherapy (IORT) for treating advanced head and neck cancers, preliminary information was obtained o... | C04 |
8,248 | 8,648 | Indomethacin responsive hypercalcaemia associated with a renal sarcoma.
An infant presented with a non-metastatic renal spindle cell sarcoma and hypercalcaemia, which resolved after treatment with indomethacin.
There was in vivo and in vitro evidence that hypercalcaemia was mediated by circulatory prostaglandins. | C04 |
8,249 | 3,640 | Complications associated with limb salvage for extremity sarcomas and their management.
A retrospective clinical review of 100 consecutive patients with extremity sarcomas managed by limb salvage operations was performed to evaluate local tumor control and morbidity.
The mean follow-up period was 45.1 months.
Overal... | C04 |
8,250 | 96 | Effects of recombinant human interleukin-3 on human hematopoietic progenitor and precursor cells in vivo.
DNA-synthesis rates and concentrations of bone marrow (BM) and peripheral blood (PB) progenitor cells were studied in 22 patients treated with recombinant human interleukin-3 (rhIL3) as part of a clinical phase I/... | C04 |
8,251 | 5,963 | Detection of bcr-abl fusion in chronic myelogeneous leukemia by in situ hybridization.
Chronic myelogeneous leukemia (CML) is genetically characterized by fusion of the bcr and abl genes on chromosomes 22 and 9, respectively.
In most cases, the fusion involves a reciprocal translocation t(9;22)(q34;q11), which produc... | C04 |
8,252 | 4,299 | Sensitivity of digoxigenin and biotin labelled probes for detection of human papillomavirus by in situ hybridisation.
The sensitivity of digoxigenin and biotin labelled DNA probes for the detection of human papillomavirus (HPV) by dot blotting and in situ hybridisation was compared in tissues from cervical, laryngeal,... | C04 |
8,253 | 6,836 | Positive results of combined therapy of surgery and intraperitoneal hyperthermic perfusion for far-advanced gastric cancer.
To evaluate the clinical efficacy of intraperitoneal hyperthermic perfusion (IPHP) for far-advanced gastric cancer, particularly with peritoneal seeding, we investigated the survival times of 59 ... | C04 |
8,254 | 8,351 | Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth.
Neovascularization is critical for the growth of tumours and is a dominant feature in a variety of angiogenic diseases such as diabetic retinopathy, haemangiomas, arthritis and psoriasis.
Recognition of the potential therapeutic b... | C04 |
8,255 | 2,426 | Features distinguishing secondary achalasia from primary achalasia.
Eighteen patients with cancer-induced or secondary achalasia (SA) were compared to 421 patients with idiopathic or primary achalasia (PA).
The aim of the study was to detect any differences in clinical presentation between the two groups.
Mean age o... | C04 |
8,256 | 9,106 | Vaccination against tumor cells expressing breast cancer epithelial tumor antigen.
Ninety-one percent of breast tumors aberrantly express an epithelial tumor antigen (ETA) identified by monoclonal antibody H23.
Vaccinia virus recombinants expressing tumor antigens have considerable promise in the active immunotherapy... | C04 |
8,257 | 8,940 | Bolus versus infusion regimens of etoposide and cisplatin in treatment of non-small cell lung cancer: a study of the North Central Cancer Treatment group
In an effort to test clinically the hypothesis that the duration of cellular exposure to etoposide (VP-16) and cisplatin (CDDP) is an important determinant of cytot... | C04 |
8,258 | 7,089 | Induction of in vitro graft-versus-leukemia activity following bone marrow transplantation for chronic myeloid leukemia.
We studied the in vitro effects of lymphokine-activated killer (LAK) cells from the peripheral blood of chronic myeloid leukemia (CML) patients after allogeneic and syngeneic bone marrow transplanta... | C04 |
8,259 | 9,626 | Preoperative cytology and mammography in patients with single-duct nipple discharge treated by surgery.
Microdochectomy has been the routine management for single-duct nipple discharge.
Our review of 176 consecutive patients surgically treated between 1975 and 1988 revealed eight patients with in situ carcinomas and ... | C04 |
8,260 | 8,955 | Symptomatic pericardial effusion in breast cancer patients: the role of fluid cytology.
Clinical and cytologic findings in 21 breast cancer patients with symptomatic pericardial effusion are presented.
The etiology of the pericardial effusion was definitely malignant, by cytology/histology in 13 patients (62%), and s... | C04 |
8,261 | 4,019 | Expandable biliary metal stents for malignancies: endoscopic insertion and diathermic cleaning for tumor ingrowth.
Seventeen patients with malignant biliary strictures have been treated by endoscopic insertion of self-expandable metallic prostheses.
Two patients received two prostheses inserted simultaneously in both... | C04 |
8,262 | 203 | Chondrosarcoma of bone in children.
Chondrosarcoma of bone rarely occurs in children.
This report analyzes the clinicopathologic features in a series of 47 patients with conventional chondrosarcoma who were less than 17 years of age.
Of the 47 cases, 14 were from the Mayo Clinic files, and 33 were from our consultat... | C04 |
8,263 | 5,832 | Correlation of the structure of the transmembrane domain of the neu oncogene-encoded p185 protein with its function.
The human homologue of the neu oncogene is frequently found in human tumors.
Certain amino acid substitutions at position 664 in the transmembrane domain of the neu oncogene-encoded p185 protein produc... | C04 |
8,264 | 6,599 | Anaesthetic problems in ex situ resection of the liver.
Ex-situ resection of the liver is a new surgical technique for treatment of liver tumours not amenable to conventional surgery.
This paper describes the cardiovascular and metabolic changes that occurred in nine consecutive such patients.
No severe haemodynamic... | C04 |
8,265 | 5,598 | Multiple myeloma and bullous lichenoid lesions: an unusual association.
Many associations of lichenoid reactions have been described but this case appears to be a previously unreported association--with multiple myeloma.
This case also demonstrates the necessity of a mucosal biopsy with adequate hematologic and serol... | C04 |
8,266 | 3,115 | Atrial fibrillation with cardiac tamponade as the initial manifestation of malignant pericarditis
This article describes the case of a 72-year-old woman with cardiac tamponade and atrial fibrillation as the initial manifestation of a lymphoid malignancy.
The pathogenesis of cardiac tamponade, various diagnostic moda... | C04 |
8,267 | 3,254 | The effect of abdominal surgery on the serum concentration of the tumour-associated antigen CA 125.
The CA 125 assay is used to monitor the course of disease in women with adenocarcinoma of the genital tract.
We measured serum CA 125 levels longitudinally in three different groups of patients who had normal serum CA ... | C04 |
8,268 | 3,334 | Bile acids and the increased risk of colorectal tumours after truncal vagotomy.
An association between colorectal cancer and previous peptic ulcer surgery is reported.
In a prospective screening study, 100 asymptomatic patients (80 men and 20 women) who had undergone truncal vagotomy at least 10 years previously were... | C04 |
8,269 | 3,404 | Genetic diagnosis of Lynch syndrome II in an extended colorectal cancer-prone family.
Knowledge of colon cancer genetics, with particular attention to precision in hereditary cancer syndrome diagnosis, can often enable highly targeted surveillance and management strategies for patients at high genetic risk.
Unfortuna... | C04 |
8,270 | 8,298 | Primary osteosarcoma of the lung. Report of two cases and review of the literature.
Two cases of primary osteosarcoma of the lung are presented.
In one case, the radiologic, clinical, and cytologic findings led to a preoperative diagnosis of undifferentiated carcinoma of the lung.
In the second case, a lung nodule w... | C04 |
8,271 | 6,574 | Variations in sensitivity after sectioning the intercostobrachial nerve.
The authors present a prospective study of the variations in sensitivity that appear in the armpit and arm after the intercostobrachial nerve has been sectioned in a modified radical mastectomy.
Of a total of 208 patients studied between 1978 an... | C04 |
8,272 | 5,225 | Metastatic tumors of the umbilicus: a review 1830-1989.
Umbilical metastases from known and unknown primary cancers are rare.
The eponym "Sister Mary Joseph's nodule" has been used by generations of physicians.
The first reports of this clinical sign were from Walshe in 1846.
A review of the literature revealed 265... | C04 |
8,273 | 5,601 | Thermally induced 'nicotine' stomatitis. A case report.
A palatal lesion resembling "nicotine" stomatitis was found in a woman who did not smoke.
However, the patient frequently drank extremely hot beverages.
After she was instructed to reduce the temperature of the beverages, the lesion almost completely resolved.
... | C04 |
8,274 | 2,657 | Patterns of cervical lymph node metastasis from squamous carcinomas of the upper aerodigestive tract.
A consecutive series of 1,081 previously untreated patients undergoing 1,119 radical neck dissections (RNDs) for squamous carcinoma of the head and neck was reviewed to study the patterns of nodal metastases.
Primary... | C04 |
8,275 | 8,491 | Prognostic significance of nondiploid DNA determined by flow cytometry in sporadic and familial medullary thyroid carcinoma.
To clarify the role of DNA measurements in predicting outcome after surgical treatment of medullary thyroid carcinoma (MTC), we performed flow cytometric analysis in nuclear suspensions of 119 M... | C04 |
8,276 | 7,091 | Deletion of the human retinoblastoma gene in primary leukemias.
As an initial step in evaluating the role of tumor suppressor genes in leukemogenesis, we surveyed primary leukemia cells from 130 patients for possible deletion of the retinoblastoma susceptibility (Rb) gene by Southern blot analysis.
Two of them clearl... | C04 |
8,277 | 5,476 | Maffucci's syndrome with bilateral cartilaginous tumors of the cerebellopontine angle.
Maffucci's syndrome is characterized by the combination of multiple enchondromas (Ollier's disease) and hemangiomatosis.
These hemangiomas develop in the subcutaneous tissue and form red-blue tumors dispersed over the whole body.
... | C04 |
8,278 | 4,913 | Breast cancer screening: who should be included?
The recommendations of the U.S.
Preventive Services Task Force are reviewed in regard to screening for breast cancer.
In contradistinction to those issued by some other national organizations, screening for breast cancer using mammography at ages 40-49 is not recommen... | C04 |
8,279 | 7,623 | Patency rate of implantable devices during long-term intraarterial chemotherapy.
Intraarterial implantable drug delivery systems have been considered as an alternative method for treating patients with unresectable liver malignancies.
However, catheter problems with external implanted devices have resulted in limited... | C04 |
8,280 | 3,288 | Ph-negative chronic myeloid leukemia: molecular analysis of ABL insertion into M-BCR on chromosome 22.
Leukemic cells from a patient with Ph-negative chronic myeloid leukemia (CML) had a normal karyotype.
M-BCR was rearranged and chromosome in situ hybridization showed an ABL insertion between 5' and 3' M-BCR on an a... | C04 |
8,281 | 8,798 | Endoscopic and radiographic evaluation of the murine colon.
Endoscopic and radiographic techniques have not been widely applicable in the evaluation of chemically induced murine colon cancer.
The authors investigated methods of cleansing the rat colon and refined endoscopic and radiographic techniques.
They compared... | C04 |
8,282 | 7,770 | Piroxicam decreases postirradiation colonic neoplasia in the rat.
This study evaluated the effects of the nonsteroidal antiinflammatory agent piroxicam on chronic radiation proctitis in the rat.
Forty female Wistar rats received a 2250-cGy dose of irradiation to the distal 2 cm of the colon.
Twenty received piroxica... | C04 |
8,283 | 5,224 | Colon carcinoma associated with ureterosigmoidostomy.
A patient developing a colonic adenoma 38 years following ureterosigmoidostomy is presented.
The mechanisms of neoplastic transformation associated with ureterosigmoidostomy is now better understood.
This knowledge is being applied to develop modifications both o... | C04 |
8,284 | 594 | Resolution of inferior vena cava syndrome after embolization of a hepatic adenoma.
A 77-year-old man presented with severe pruritus and massive lower body edema.
Computerized axial tomography of the abdomen showed a large hepatic mass compressing the inferior vena cava, and a liver biopsy specimen showed hepatic aden... | C04 |
8,285 | 989 | Campylobacter pylori interactions with gastric cell tissue culture.
Many investigators have reported that gastric mucosal biopsies of patients with chronic gastritis and peptic ulcer disease show the presence of Campylobacter pylori in a large majority of cases.
Histologic examinations of such tissues indicate a clos... | C04 |
8,286 | 4,577 | Insulin-like growth factor-I supports proliferation of autocrine thymic lymphoma cells with a pre-T cell phenotype.
We have studied the phenotypic characteristics and growth properties of murine T lymphoma cell lines derived from primary x-ray-induced thymic lymphomas at the earliest stage at which they can be detecte... | C04 |
8,287 | 2,111 | Synchronous carcinoma of the colon and rectum.
Reports on the incidence of synchronous carcinoma of the colon and rectum have varied from 2 to 11 per cent.
The variability is a result of a lack of uniformity in criteria of diagnosis, differences in the population studied and differences in time period used.
In this ... | C04 |
8,288 | 2,483 | Genetics and biology of human ovarian teratomas. I. Cytogenetic analysis and mechanism of origin.
One hundred and two benign, mature ovarian teratomas and two immature, malignant teratomas were karyotyped and scored for centromeric heteromorphisms as part of an ongoing project to determine the chromosomal karyotype an... | C04 |
8,289 | 5,123 | In situ hybridization of prostate-specific antigen mRNA in human prostate.
Prostate-specific antigen (PSA) mRNA was detected by in situ hybridization utilizing a 428 base pair [35S]-labelled cDNA probe from the 3' noncoding region of the PSA gene.
Thirty six fresh surgical specimens were collected from patients under... | C04 |
8,290 | 6,383 | The importance of cytogenetic studies in adult acute lymphocytic leukemia.
PURPOSE: The prognostic importance of pretreatment bone marrow cytogenetic studies in adults with acute lymphocytic leukemia treated at a single institution, with an identical treatment program, is described.
PATIENTS AND METHODS: A total of 1... | C04 |
8,291 | 4,995 | Parotid gland and facial nerve trauma: a retrospective review.
Included in this study are all patients with trauma to the parotid region seen at our center from 1979 to 1989.
There was a total of five patients with injury to the parotid area: two patients with isolated facial nerve injury; one with isolated parotid d... | C04 |
8,292 | 7,360 | Chondrosarcoma of the head and neck.
Chondrosarcoma is a malignancy rarely encountered in the head and neck.
In an attempt to define this tumor's characteristics and response to therapy, all cases of chondrosarcoma treated at the University of Michigan over the past 25 years were retrospectively studied.
Fourteen ca... | C04 |
8,293 | 7,231 | Adverse mortality experience of a southwestern American Indian community: overall death rates and underlying causes of death in Pima Indians.
As part of an ongoing epidemiologic study, the death rate and causes of death during 1975 through 1984 were determined in Pima Indians who resided in the Gila River Indian Commu... | C04 |
8,294 | 2,503 | Equal parental origin of chromosome 22 losses in human sporadic meningioma: no evidence for genomic imprinting.
Inactivation of tumor suppressor genes can occur either by mutation at the gene locus or by loss of part or all of the chromosome region containing the gene.
The latter is most frequently detected by DNA ma... | C04 |
8,295 | 4,054 | Pathological observations of intrahepatic peribiliary glands in 1,000 consecutive autopsy livers. III. Survey of necroinflammation and cystic dilatation.
Pathological changes and significance of intrahepatic peribiliary glands, hitherto poorly recognized intrahepatic elements, have been evaluated in our laboratory.
I... | C04 |
8,296 | 7,505 | Trends in conserving treatment of invasive carcinoma of the breast in females.
This population-based study presents trends in the treatment of node-negative invasive carcinoma of the breast in females during the 1980s in the Detroit metropolitan area.
It was done to determine whether or not there has been a significa... | C04 |
8,297 | 582 | Pancreatic secretory trypsin inhibitor stimulates the growth of rat pancreatic carcinoma cells.
Pancreatic secretory trypsin inhibitor was examined for growth-promoting activity on five cell lines using standard cell culture techniques.
One cell line, AR4-2J, derived from a rat pancreatic acinar cell carcinoma, respo... | C04 |
8,298 | 9,738 | Function after amputation, arthrodesis, or arthroplasty for tumors about the knee.
We studied the function of twenty-two patients who had had a malignant skeletal tumor adjacent to the knee.
An above-the-knee amputation was done in seven; a resection arthrodesis, in nine; and a replacement arthroplasty, in six.
The ... | C04 |
8,299 | 7,585 | Angiocentric lymphoma with histologic features of neoplastic angioendotheliomatosis presenting with predominant respiratory and hematologic manifestations. Report of a case and review of the literature
Neoplastic angioendotheliomatosis (NAE) is a rare fatal disease characterized by widespread intravascular proliferat... | C04 |
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