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9,000 | 5,759 | Transfer of secretory proteins from the endoplasmic reticulum to the Golgi apparatus: discrimination between homologous and heterologous transfer in intact heterokaryons.
To examine aspects of the transfer of secretory proteins from the endoplasmic reticulum to the Golgi apparatus in situ, heterokaryons were formed be... | C04 |
9,001 | 2,258 | Selenium. Nutritional, toxicologic, and clinical aspects
Despite the recent findings of environmental contamination, selenium toxicosis in humans is exceedingly rare in the United States, with the few known cases resulting from industrial accidents and an episode involving the ingestion of superpotent selenium supple... | C04 |
9,002 | 2,643 | Survival discriminants for differentiated thyroid cancer.
Since 1975, the American Cancer Society, Illinois Division, has published end results of major cancer sites drawn from patient data contributed voluntarily by hospital cancer registries throughout the state.
The current study was undertaken, in part, to appreh... | C04 |
9,003 | 2,785 | Functional character and augmentation of lymphocytes in regional lymph nodes of patients with lung cancer.
It appears that lymph node metastases are more frequent in lung cancer than in other cancers because of impaired defensive mechanisms in the regional lymph nodes.
However, little is known about the immunologic f... | C04 |
9,004 | 3,136 | Platelet norepinephrine and epinephrine concentration in patients with pheochromocytoma.
Platelet and plasma catecholamine concentrations were determined in 17 patients with surgically proven pheochromocytoma (mean age 42.3 years); in 31 patients with borderline hypertension (mean age 35.3 years) and in 9 healthy cont... | C04 |
9,005 | 227 | A clinical and flow cytometric analysis of patients with nasopharyngeal cancer.
Abnormal cellular DNA content, a hallmark of malignancy, is known to be an important prognostic factor in many human solid tumors; however, no data have been published on whether cellular DNA content carries prognostic significance for pat... | C04 |
9,006 | 2,978 | Fast and effective treatment of malignant hypercalcemia. Combination of suppositories of calcitonin and a single infusion of 3-amino 1-hydroxypropylidene-1-bisphosphonate.
Seventeen patients with malignant hypercalcemia were treated with a combination of a single dose of 3-amino 1-hydroxypropylidene-1-bisphosphonate (... | C04 |
9,007 | 9,084 | Mapping chromosome band 11q23 in human acute leukemia with biotinylated probes: identification of 11q23 translocation breakpoints with a yeast artificial chromosome.
Translocations involving chromosome 11, band q23, are frequent recurring abnormalities in human acute lymphoblastic and acute myeloid leukemia.
We used ... | C04 |
9,008 | 3,085 | Pseudotumor of the craniocervical junction during long-term hemodialysis.
A systematic study of the upper cervical spine was performed using magnetic resonance imaging in 25 patients (15 men and 10 women) who had been undergoing hemodialysis for more than 10 years.
Seven pseudotumors of the periodontoid soft tissue w... | C04 |
9,009 | 2,159 | Long-term results of surgical resection of locally advanced colorectal carcinoma.
This study was undertaken to review the long-term results of multivisceral resection of locally advanced colorectal carcinoma.
Between 1964 and 1980, 1042 patients underwent exploratory surgery for colorectal cancer.
Of these, 58 patie... | C04 |
9,010 | 4,952 | Interaction between trimethoprim-sulfamethoxazole and methotrexate in children with leukemia.
Because trimethoprim-sulfamethoxazole (TMP-SMX) causes neutropenia in children with leukemia, we investigated the possibility that pharmacokinetic interaction between methotrexate (MTX) and TMP-SMX causes accumulation of the ... | C04 |
9,011 | 8,008 | Clinical application of ras gene mutation for diagnosis of pancreatic adenocarcinoma.
Most pancreatic adenocarcinomas are known to have ras gene (oncogene) mutations.
The site of the mutations is localized in codon 12 of K-ras gene.
Such high incidence and localization of the ras gene mutations have not been observe... | C04 |
9,012 | 5,451 | Multiple intracranial tumors of different cell types.
Multiple intracranial tumors of different cell types are rare.
We report nine patients with multiple intracranial tumors, who did not have a history of trauma, irradiation, or phacomatosis.
The clinical, radiological, and histopathological findings as well as ind... | C04 |
9,013 | 5,395 | Relation of meat, fat, and fiber intake to the risk of colon cancer in a prospective study among women.
BACKGROUND.
The rates of colon cancer in various countries are strongly correlated with the per capita consumption of red meat and animal fat and, to a lesser degree, inversely associated with the consumption of fi... | C04 |
9,014 | 5,296 | Carcinoma of the external auditory canal: an update.
This review is a continuation of the series of 35 cases of carcinoma of the external auditory canal originally reported by the senior author and colleagues.
Eighteen additional cases have been evaluated and treated since 1976.
Preoperative high-resolution computed... | C04 |
9,015 | 2,665 | Cervical lymph nodes from an unknown primary tumor in 190 patients.
Over 10 years, 475 patients with isolated lateral neck masses were evaluated: 190 with lymph nodes from an unknown primary tumor (LNUP), 188 with neck lymphomas, 78 with benign tumors, 10 with sarcomas, and 9 with chemodectomas.
This study focused on... | C04 |
9,016 | 3,292 | In vitro rosetting, cytoadherence, and microagglutination properties of Plasmodium falciparum-infected erythrocytes from Gambian and Tanzanian patients.
To understand the molecular mechanisms that lead to sequestration of red blood cells infected with mature stages of Plasmodium falciparum and to examine the relevance... | C04 |
9,017 | 6,747 | Jejunal-rectal fistula as a complication of postoperative radiotherapy.
We present the case of a patient with an unusual, complex enteric fistula with multiple tracts and associated abscesses.
The fistula was a late complication of radiotherapy, administered three years earlier, after resection for carcinoma of the s... | C04 |
9,018 | 6,067 | The role of gastric resection in the management of multicentric argyrophil gastric carcinoids.
A patient with pernicious anemia, atrophic non-antral gastritis, hypergastrinemia, and widespread hyperplasia of enterochromaffin-like cells and manifest enterochromaffin-like cell carcinoma was followed up during 39 months,... | C04 |
9,019 | 4,704 | Rhinosporidiosis associated with squamous cell carcinoma in the tongue.
The peritumoural region of a squamous cell carcinoma of the tongue when examined with light and electron microscope showed nodular bodies in the submucosa with all the distinctive features of 'sporangium and 'spores' of rhinosporidiosis.
The occu... | C04 |
9,020 | 2,457 | Genitourinary cancer in the elderly.
The subject of genitourinary cancer in the elderly becomes increasingly more important as our population of patients older than 50 years expands.
Carcinoma of the kidney, bladder, and prostate all have an increasing incidence over the age of 50 and have a predilection for afflicti... | C04 |
9,021 | 2,896 | Histopathologic spectrum of clinically atypical melanocytic nevi. II. Studies of nonfamilial melanoma [published erratum appears in Arch Dermatol 1990 Dec;126(12):1616]
We studied the clinically most atypical pigmented lesion removed from each of 142 patients with newly diagnosed sporadic melanoma.
The specimens were... | C04 |
9,022 | 8,406 | Purification and characterization of an inhibitor (soluble tumor necrosis factor receptor) for tumor necrosis factor and lymphotoxin obtained from the serum ultrafiltrates of human cancer patients.
Serum ultrafiltrates (SUF) from human patients with different types of cancer contain a blocking factor (BF) that inhibit... | C04 |
9,023 | 9,642 | Vastus lateralis myocutaneous flap for reconstruction of defects around the groin and pelvis.
We present our experience using the vastus lateralis myocutaneous flap for the repair of defects around the groin and pelvis.
It is a relatively new technique, with many advantages over other flaps used in this area, though ... | C04 |
9,024 | 5,616 | Clinical and instrumental evaluation of sensory function before and after percutaneous anterolateral cordotomy at cervical level in man.
Sensory perception thresholds were assessed by clinical testing and by quantitative instrumental testing before and after operation in 16 subjects for whom unilateral percutaneous ce... | C04 |
9,025 | 3,422 | Possible involvement of the retinoblastoma gene in undifferentiated sinonasal carcinoma.
Retinoblastoma tumor formation is initiated by the loss of function of both alleles of the RB-1 gene on chromosome 13.
Patients with the hereditary form of retinoblastoma carry a germ line mutation at one of the two homologous ge... | C04 |
9,026 | 9,186 | Failure to limit quantities of benzodiazepine hypnotic drugs for outpatients: placing the elderly at risk.
PURPOSE: The long-term use of benzodiazepine hypnotics by the elderly is associated with serious side effects, and prescriptions of large quantities of these agents allow such use.
Therefore, we determined the q... | C04 |
9,027 | 6,796 | Histopathologic grading of salivary gland neoplasms: II. Acinic cell carcinomas.
Acinic cell carcinomas display varied cytoarchitectural patterns of growth that should allow for formulation of histopathologic grading.
Grading of these carcinomas may serve to identify subsets whose biologic behavior is more aggressive... | C04 |
9,028 | 2,161 | Follicular cell predominance in the cytologic examination of dominant thyroid nodules indicates a sixty percent incidence of neoplasia.
The interpretation of aspiration cytologic smears that contain a predominance of follicular components often presents a dilemma to the clinician who is treating a patient who has a do... | C04 |
9,029 | 4,355 | Cutaneous horn of the penis: its association with squamous cell carcinoma and HPV-16 infection.
Cutaneous horns of the penis are rare.
Including this case, only 19 cases have been reported in the English-language literature.
In 37% of the reported cases a malignant tumor was found beneath the cutaneous horn.
Our ca... | C04 |
9,030 | 5,475 | Subdural hematoma associated with metastatic neoplasms.
Two cases of subdural hematoma, one acute and the other chronic, associated with cancer metastatic to the dura are reported.
Various mechanisms of the association of hematomas with cancer are reviewed. | C04 |
9,031 | 5,054 | Pheochromocytoma in the pediatric age group: the prostate--an unusual location.
Pheochromocytomas of the prostate are rare, with only 3 cases in adults reported in the literature.
We present the case of an 8-year-old boy with a pheochromocytoma of the prostate and a second tumor in the region of the left internal ili... | C04 |
9,032 | 8,190 | Antigen-induced cross-linking of the IgE receptor leads to an association with the detergent-insoluble membrane skeleton of rat basophilic leukemia (RBL-2H3) cells.
Cross-linking of the IgE receptor on the surface of rat basophilic leukemia cells by multivalent Ag (DNP-BSA) causes a rapid conversion to a detergent-ins... | C04 |
9,033 | 8,020 | Screening colonoscopy in asymptomatic average-risk persons with negative fecal occult blood tests.
Colonoscopy was performed on 210 asymptomatic average-risk persons, aged 50-75 years, who had negative fecal occult blood test results.
Colonoscopy was complete to the cecum in 209 subjects.
Fifty-three subjects (25%) ... | C04 |
9,034 | 8,772 | Surgical approach to the retrocrural lymph nodes.
Removal of retrocrural lymph nodes requires an approach other than the infradiaphragmatic retroperitoneal access generally used in the surgical management of testicular tumours.
The transperitoneal route given access, at best, to the origin of the superior mesenteric ... | C04 |
9,035 | 4,698 | Second primary tumours of the larynx following bronchial carcinoma.
The occurrence of multiple primary malignancies in patients with laryngeal cancer is well known.
The possibility that lung cancer patients may be at risk of subsequent laryngeal cancer is less well recognized.
The possibility of laryngeal cancer dev... | C04 |
9,036 | 4,381 | Lip paresthesia associated with a jaw mass.
A case is reported in which mandibular swelling and lower lip numbness were the first signs of a metastatic adenocarcinoma of the lung.
The development of paresthesia, with or without other oral symptoms, requires that a diagnosis of malignancy be considered until confirmed... | C04 |
9,037 | 5,040 | The relationship of prostate specific antigen levels and residual tumor volume in stage A prostate cancer.
Preoperative serum prostate specific antigen correlates well with morphometrically determined prostate tumor volume in prostatectomy specimens.
However, since prostate specific antigen is produced by hyperplasti... | C04 |
9,038 | 82 | Characterization of a factor-dependent acute leukemia cell line with translocation (3;3)(q21;q26).
A strictly factor-dependent cell line (UCSD/AML1) was established from a patient with the syndrome of multilineage acute leukemia with high platelets.
The patient's cells and the cell line karyotype were 45,XX,-7,t(3;3)... | C04 |
9,039 | 7,578 | Immunocytochemical profile of benign and carcinomatous effusions. A practical approach to difficult diagnosis.
One of the great challenges in the cytodiagnosis of effusions is the distinction between reactive mesothelium/histiocytes and cancer cells.
This is notably true in patients having undergone radiation and/or ... | C04 |
9,040 | 3,377 | Primary chemotherapy with or without radiation therapy and/or surgery for children with localized sarcoma of the bladder, prostate, vagina, uterus, and cervix. A comparison of the results in Intergroup Rhabdomyosarcoma Studies I and II.
A major objective of the second Intergroup Rhabdomyosarcoma Study (IRS-II) (1978 t... | C04 |
9,041 | 4,603 | Premalignant lesions and cancers of the skin in the general population: evaluation of the role of human papillomaviruses.
To evaluate the role of human papillomaviruses (HPV) in the development of premalignant lesions and cancers of the skin in the general population, 314 biopsies obtained from 227 patients with benig... | C04 |
9,042 | 9,255 | Kaposi's sarcoma of the rectum in patients with the acquired immunodeficiency syndrome.
We retrospectively reviewed eight patients with biopsy-proven anorectal Kaposi's sarcoma (KS) treated between 1984 and 1989 at San Francisco General Hospital.
All patients were homosexual men with the acquired immunodeficiency syn... | C04 |
9,043 | 386 | Oncocytic glomus tumor of the trachea.
An oncocytic variant of glomus tumor of the trachea occurred in a 47-year-old woman.
She experienced intermittent cough and hemoptysis for about three years.
Bronchoscopy and chest CT scan showed a small reddish polypoid tumor on the lower end of the trachea.
Bronchoscopic bio... | C04 |
9,044 | 778 | Unusual haemostasis for an unusual tumour. Catastrophic bleeding from a tactile neurofibroma affecting the thoracic vertebrae. Case report.
The symptomatology of a typical acute descending thoracic aorta dissection was imitated by profuse haemorrhage caused by a benign tumour composed almost exclusively of Wagner-Meis... | C04 |
9,045 | 9,373 | Acquired childhood aphasia. Outcome 1 year after onset.
The effects of the variables age at onset, cause, severity and bilaterality of lesion, and type of aphasia on course and outcome were investigated in a group of 28 aphasic children.
Analysis of spontaneous speech and tests of auditory verbal comprehension were u... | C04 |
9,046 | 2,662 | Lateral temporal bone resections.
Eighteen consecutive patients underwent a lateral temporal bone resection for the treatment of tumors originating in the auricle, the external auditory canal, the periauricular skin, or the parotid and were retrospectively analyzed.
The different lateral temporal bone resections perf... | C04 |
9,047 | 7,176 | Whole-body lipolysis and triglyceride-fatty acid cycling in cachectic patients with esophageal cancer.
Whole-body lipolytic rates and the rate of triglyceride-fatty acid cycling (reesterification of fatty acids released during lipolysis) were measured with stable isotopic tracers in the basal state and during beta-adr... | C04 |
9,048 | 8,758 | Dilatation in the duplex kidney: 3 unusual cases.
Dilatation in the upper limb of a duplex ureter is usually secondary to obstruction and may be associated with a ureterocele.
By contrast, vesicoureteric reflux is the usual cause of a dilated lower moiety ureter.
We report 3 cases in which unusual or complex causes ... | C04 |
9,049 | 3,278 | Human basophils express interleukin-4 receptors.
Interleukin-4 (IL-4), a multipotential lymphokine reputed to play an important role in the regulation of immune responses, interacts with a variety of hemopoietic target cells through specific cell surface membrane receptors.
The present study was designed to investiga... | C04 |
9,050 | 9,416 | Morphine-induced transactivation of HIV-1 LTR in human neuroblastoma cells.
Infection by human immunodeficiency virus (HIV) is followed in many cases by a clinically quiescent or latent phase that appears to continue as long as host antiviral defense is intact.
This has raised the possibility that certain host suscep... | C04 |
9,051 | 8,933 | Ability of circular extrachromosomal DNA molecules to carry amplified MYCN proto-oncogenes in human neuroblastomas in vivo.
Amplification of the proto-oncogene MYCN (also known as N-myc) in neuroblastomas has been shown to correlate with both disease stage and prognosis, yet little is known about the DNA structures th... | C04 |
9,052 | 5,291 | 1990 Ogura memorial lecture: moral dilemmas in head and neck cancer.
Neither morality nor dilemma can be defined meaningfully in the concept of the practical management of head and neck cancer.
Although both have important implications, particularly with regard to ethnic and social factors, they play a relatively min... | C04 |
9,053 | 3,006 | Mucinous cystadenoma of the lung. A report of two cases with immunohistochemical and ultrastructural analysis.
We describe two patients who presented with solitary pulmonary masses that consisted of unilocular cysts lined by columnar mucinous epithelium.
The cysts contained copious mucus.
The epithelial lining of th... | C04 |
9,054 | 4,716 | Effect of microwave and ionizing radiation in patients with recurrent laryngeal carcinoma.
This study describes the treatment and survival of 54 patients with gross recurrent laryngeal carcinoma after radiotherapy.
Twenty-six patients were treated with local ultra-high frequency hyperthermia in combination with radio... | C04 |
9,055 | 3,784 | Endometrioma. An intra-abdominal troublemaker.
A ten-year review of intestinal and abdominal wall endometriomas is reported.
Seven cases of intestinal and two cases of abdominal wall endometriomas are presented.
Symptoms were varied but a majority had some gynecologic complaint.
In this select group of patients, pr... | C04 |
9,056 | 220 | Significance of blasts in low-cell-count cerebrospinal fluid specimens from children with acute lymphoblastic leukemia.
The purpose of this study was to determine whether the presence of more than 5% blasts in a differential count of cytocentrifuged cerebrospinal fluid (CSF) with less than 6 leukocytes/microliter was ... | C04 |
9,057 | 3,432 | Infiltration of dendritic cells in relation to tumor invasion and lymph node metastasis in human gastric cancer.
The infiltration of dendritic cells determined in 210 patients with gastric carcinoma was investigated from the standpoint of tumor invasion, lymph node metastasis, and prognosis.
Dendritic cell infiltrati... | C04 |
9,058 | 3,435 | Intraoral adenoid cystic carcinoma. The presence of perineural spread in relation to site, size, local extension, and metastatic spread in 22 cases.
Twenty-two patients with an intraoral adenoid cystic carcinoma (ACC), initially treated by surgery with or without postoperative radiotherapy, were examined for the prese... | C04 |
9,059 | 7,526 | Magnetic resonance imaging of experimental rat brain tumors: histopathological evaluation.
Using RG-C6 glioma-transplanted rats, we studied precontrast and postcontrast magnetic resonance imaging, extravasation of Evans blue, and histology.
In all rats, tumor was enhanced with gadolinium-diethylenetriaminepentaacetic... | C04 |
9,060 | 6,077 | Adoptive immunotherapy of human pancreatic cancer with lymphokine-activated killer cells and interleukin-2 in a nude mouse model.
A pancreatic cancer cell line was grown in orthotopic and heterotopic positions in young Swiss/NIH nude mice, which were tested with adoptive immunotherapy.
Mice were injected with 1 x 10(... | C04 |
9,061 | 8,686 | Parotid duct communicating with a labial pit and ectopic salivary cyst.
Labial pits are usually described as blind epidermal invaginations of lip mucosa with occasional drainage of minor salivary gland secretions.
A case of an aberrant parotid duct in communication with both a unilateral, commissural labial pit and a... | C04 |
9,062 | 2,534 | Colon cancer in pregnancy with elevated maternal serum alpha-fetoprotein level at presentation.
A case of colon cancer in pregnancy is presented in which the maternal serum alpha-fetoprotein level was elevated.
Failure to evaluate colon cancer as a cause of the elevated maternal serum alpha-fetoprotein may have accou... | C04 |
9,063 | 2,438 | In vivo evaluation of monopolar versus bipolar electrosurgical polypectomy snares.
The energy required and tissue damage in bipolar and monopolar polypectomy snares were compared in a canine model.
The bipolar snare required an average of 34 joules of energy, whereas the monopolar snare required 228 joules to cut the... | C04 |
9,064 | 7,768 | Low-dose preoperative radiation postpones recurrences in operable rectal cancer. Results of a randomized multicenter trial in western Norway.
A randomized, multicenter clinical trial was conducted in Western Norway to study the effectiveness of preoperative radiation therapy in operable rectal cancer, given at a dosag... | C04 |
9,065 | 4,014 | Caseating hepatic granulomas in Hodgkin's lymphoma.
A 68-year-old man presented with recurrent Hodgkin's lymphoma after a 9-year disease-free interval induced by chemotherapy.
In addition to histological evidence of recurrent Hodgkin's disease, the liver biopsy specimen showed extensive caseating granulomas.
Culture... | C04 |
9,066 | 9,362 | Hepatic cyst associated with Peutz-Jeghers syndrome.
A solitary hepatic cyst, associated with Peutz-Jeghers syndrome, is described.
To our knowledge, this association has not been previously reported.
A developmental anomaly or hamartomatous nature of this lesion is suggested.
Knowledge of this association may be h... | C04 |
9,067 | 5,438 | Characterization of a newly established malignant meningioma cell line of the human brain: IOMM-Lee.
A permanent malignant meningioma (MM) cell line of the human brain designated "IOMM-Lee" is reported.
This cell line was successfully established from the tumor of a 61-year-old Chinese man with repeated recurrent pri... | C04 |
9,068 | 2,227 | Local failure and related complications after definitive treatment of carcinoma of the prostate by irradiation or surgery.
The authors review their institution's experience with the failure of definitive treatment to achieve local tumor control and with the distant dissemination and local morbidity associated with suc... | C04 |
9,069 | 7,644 | Intraocular lens complications.
The authors implanted intraocular lenses (IOL) in 780 eyes and considered complications of this surgery, dividing the complications into intraoperative and postoperative, the latter early and late.
The most frequent intraoperative complications were: hyphema, vitreous injury, pupil def... | C04 |
9,070 | 8,281 | Laser therapy for vaginal intraepithelial neoplasia after hysterectomy.
In recent years there has been a marked increase in the number of reported cases of vaginal intraepithelial neoplasia (VAIN) after hysterectomy.
Until about 10 years ago radiation or surgery had been the therapeutic modality mostly used for this ... | C04 |
9,071 | 318 | A newly established human osteosarcoma cell line with osteoblastic properties.
A human osteosarcoma cell line, HuO9, was established from a tumor that was heterotransplanted into athymic nude mice.
Antiserum against nude mouse spleen cells was added to the early passage cultures to eliminate the host fibroblastic cel... | C04 |
9,072 | 9,921 | Incidence of polymyositis-dermatomyositis: a 20-year study of hospital diagnosed cases in Allegheny County, PA 1963-1982.
The incidence of hospital diagnosed polymyositis-dermatomyositis (PM-DM) among residents of Pittsburgh and Allegheny County, PA was determined from 1963 to 1982.
Medical records of all Allegheny C... | C04 |
9,073 | 225 | Comparison of DNA content in gastric cancer cells between primary lesions and lymph node metastases.
Cytophotomtric DNA contents of tumor cells in primary lesions and the corresponding metastatic lymph nodes were compared in 61 cases of gastric cancer to determine whether the DNA content remains stable during lymph no... | C04 |
9,074 | 234 | Flow cytometric DNA-ploidy analysis of synchronously occurring multiple malignant tumors of the female genital tract.
In this study the authors applied flow cytometric DNA-ploidy analysis to multiple female genital tract malignant tumors in 43 patients, most of whom (n = 37) had bilateral ovarian cancer.
An algorithm... | C04 |
9,075 | 679 | HBV-DNA sequences in tumor and nontumor tissue in a patient with the fibrolamellar variant of hepatocellular carcinoma.
One patient with the fibrolamellar variant of hepatocellular carcinoma was found to be seropositive for HBsAg and anti-HBe.
DNA from tumor and nontumor areas of the liver was examined by molecular h... | C04 |
9,076 | 4,304 | Importance of sampling method in DNA analysis of lung cancer.
Lung carcinomas are characterised by considerable histological variation within the tumour.
The possible effects of this morphological heterogeneity on the estimation of tumour ploidy were investigated.
Multiple tissue blocks were systematically taken fro... | C04 |
9,077 | 7,375 | Prophylaxis of aphakic cystoid macular edema without corticosteroids. A paired-comparison, placebo-controlled double-masked study.
Prior investigations have reported that topical nonsteroidal anti-inflammatory drug (NSAID) therapy prevents the development of postoperative angiographic signs of angiographic cystoid mac... | C04 |
9,078 | 3,004 | Persistence of mucosal gastric carcinomas for 8 and 6 years in two patients.
A small gastric carcinoma was detected in a man, but he refused surgery.
Eight years later, he was readmitted for a check-up, and a partial gastrectomy was performed.
Pathologic examination revealed a well-differentiated adenocarcinoma rest... | C04 |
9,079 | 4,978 | Inhibition of invasion of invasive human bladder carcinoma cells by protein kinase C inhibitor staurosporine.
To study the effect of the protein kinase C (PKC) inhibitor staurosporine on invasion, we selected the invasive human bladder carcinoma cell line EJ.
Total PKC activity was more than twofold higher in the EJ ... | C04 |
9,080 | 9,242 | Characteristics of duodenal wall gastrinomas.
Fifteen patients with duodenal wall gastrinomas (DWGs) and the Zollinger-Ellison syndrome have been treated since 1960.
In 6 of 11 patients, DWGs were recognized at operation and totally excised.
In four patients, the tumor was subsequently found in the proximal duodenum... | C04 |
9,081 | 6,372 | The mutation for medullary thyroid carcinoma with parathyroid tumors (MTC with PTs) is closely linked to the centromeric region of chromosome 10.
Two new morphs (F and G) detected by the centromeric alpha satellite probe p alpha 10RP8 and D10Z1 in HinfI digests are linked to the PstI polymorphisms of D10Z1, confirming... | C04 |
9,082 | 8,803 | Expression of placental alkaline phosphatase in gastric and colorectal cancers. An immunohistochemical study using the prepared monoclonal antibody.
The authors developed monoclonal antibodies (MoAb) against human placental alkaline phosphatase (PLAP).
Four specific MoAb reacting only with PLAP and two nonspecific Mo... | C04 |
9,083 | 7,175 | Characterization in vitro of a human tumor necrosis factor-binding protein. A soluble form of a tumor necrosis factor receptor.
Tumor necrosis factor (TNF) is a pleiotropic mediator of inflammatory responses.
A cysteine-rich, highly glycosylated 30-kD TNF-binding protein (TNF-BP) purified from urine may have a role i... | C04 |
9,084 | 6,840 | Localization and surgical treatment of occult insulinomas.
Management of patients with biochemical evidence of insulinoma and negative preoperative imaging studies (occult) tumors is controversial, varying from primarily medical management to aggressive, blind nearly total pancreatectomy to extirpate the tumor.
Since... | C04 |
9,085 | 9,976 | Exaggerated venous mural hypertrophy in association with metastatic adenocarcinoma of the prostate.
A 61-year-old black man presented with metastases to the right groin 5 years after 125iodine treatment for a well differentiated primary prostatic adenocarcinoma.
Medium sized veins within and immediately adjacent to t... | C04 |
9,086 | 9,043 | Tissue-specific transformation by epidermal growth factor receptor: a single point mutation within the ATP-binding pocket of the erbB product increases its intrinsic kinase activity and activates its sarcomagenic potential.
Avian c-erbB is activated to a leukemia oncogene following truncation of its amino-terminal, li... | C04 |
9,087 | 3,009 | A signet-ring cell carcinoma of the ampulla of Vater.
We describe a variant of carcinoma of the ampulla of Vater, which, to our knowledge, has not been previously described.
Classic signet-ring cells represented the predominant cell type, and were admixed with more poorly differentiated tumor cells that were chromogr... | C04 |
9,088 | 3,768 | Pulmonary malignant angioendotheliomatosis. Presentation with fever and syndrome of inappropriate antidiuretic hormone.
A 64-year-old man presented with protracted fever, hyponatremia, and mononeuritis multiplex.
Inappropriate antidiuretic hormone secretion was established.
The absence of pulmonary infiltrates precl... | C04 |
9,089 | 2,664 | Efficacy of radical neck dissection for the control of cervical metastasis after radiotherapy for nasopharyngeal carcinoma.
Fifty-one patients who had persistent or recurrent neck disease from nasopharyngeal carcinoma after radiotherapy underwent radical neck dissection.
The follow-up period ranged from 0.5 to 9 year... | C04 |
9,090 | 596 | Misdiagnosis of the Zollinger-Ellison syndrome due to hyperlipidemia.
Most authorities feel that diagnosis of the Zollinger-Ellison syndrome is established when the serum gastrin level is greater than 1000 pg/mL (1000 ng/L) in a patient with gastric acid hypersecretion and clinical manifestations consistent with the d... | C04 |
9,091 | 2,387 | The use of molecular probes to distinguish new primary tumors from recurrent tumors in gynecologic malignancies.
This is the first report using DNA molecular probe technology to distinguish between recurrent tumor and a second primary malignancy in a patient.
Tumor DNA was extracted from squamous cell carcinoma of th... | C04 |
9,092 | 7,794 | Increasing incidence of cecal and sigmoid carcinoma. Data from the Connecticut Tumor Registry.
We have studied both the distribution and incidence of colorectal cancer using The Connecticut Tumor Registry, the oldest tumor registry in the United States.
During the time period 1973 to 1985, left-sided colon cancers ac... | C04 |
9,093 | 7,698 | Detection of primary colorectal cancer with indium 111 monoclonal antibody B72.3.
B72.3 is a murine monoclonal antibody of the immunoglobulin subclass IgG1 directed against TAG-72, a cell surface antigen present on colorectal carcinoma cells.
We investigated the utility of scanning with indium 111-labeled B72.3 in 16... | C04 |
9,094 | 2,873 | Bactericidal effect of doxycycline associated with lysosomotropic agents on Coxiella burnetii in P388D1 cells.
There is no consistently reliable treatment for endocarditis resulting from chronic Coxiella burnetii infection, the causative agent of Q fever.
Although certain antibiotics are recommended on the basis of t... | C04 |
9,095 | 9,251 | Selective nonoperative management of patients referred with abnormal mammograms.
Screening mammography provides a means of detecting clinically occult breast carcinoma, but the question of whether all abnormal mammograms require biopsy remains unanswered.
We retrospectively reviewed records of 214 women referred over... | C04 |
9,096 | 6,478 | Inhibition of angiogenesis and tumor growth in the brain. Suppression of endothelial cell turnover by penicillamine and the depletion of copper, an angiogenic cofactor.
Microvascular proliferation, a hallmark of malignant brain tumors, represents an attractive target of anticancer research, especially because of the q... | C04 |
9,097 | 9,438 | Shear stress induces not only platelet aggregation but also platelet-tumor cell interaction.
To investigate the interaction between platelets and tumor cells under well-defined flow conditions, the effect of tumor cells on platelet aggregation induced by shear stress was studied using a cone and plate viscometer adapt... | C04 |
9,098 | 5,570 | Visual disturbance in patients with melanocytoma of the optic disk.
Visual disturbance in 11 patients with melanocytoma of the optic disk was analyzed.
Goldmann visual field examination showed enlargement of Mariotte's blind spot in 7 of 10 patients (70%) and visual field defect or depression in 7 patients (70%).
In... | C04 |
9,099 | 3,405 | Cancer in the families of children with soft tissue sarcoma.
The cancer experience among 754 first-degree relatives (mothers, fathers, and siblings) of a population-based series of 177 children with soft tissue sarcoma is reported.
The current study represents an extension of our earlier work in which the authors fou... | C04 |
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