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9,100 | 6,982 | Management of perineal wounds following abdominoperineal resection with inferior gluteal flaps.
Our experience treating perineal wounds secondary to abdominoperineal resection, either for inflammatory bowel disease or cancer, is presented.
A total of 16 patients were treated either on a delayed basis or at the same t... | C04 |
9,101 | 2,136 | Prospective evaluation of clinical and pathologic detection of axillary metastases in patients with carcinoma of the breast.
Complete axillary dissection was performed in 287 patients undergoing modified radical mastectomy between 1984 and 1987 to identify patterns of axillary node metastases, as well as discontinuous... | C04 |
9,102 | 7,069 | The management of primary fallopian tube carcinoma.
The outcome of 30 patients with primary fallopian tube carcinoma is described.
Treatment varied over the 22 year period of accrual and included combinations of surgery, radiotherapy and chemotherapy.
There was an apparent increase in stage at treatment with time wh... | C04 |
9,103 | 2,578 | Correlations of acoustic tissue typing of malignant melanoma and histopathologic features as a predictor of death.
Forty-six eyes with uveal melanoma were scanned with a computerized diagnostic ultrasound system before enucleation, and light microscope sections were obtained.
Tumors were characterized by ultrasonical... | C04 |
9,104 | 2,246 | Staging of ureteral transitional cell carcinoma by CT and MRI.
Intravenous urography and retrograde pyelography are the primary radiologic studies for detecting ureteral carcinoma but give limited information regarding stage of disease.
Computed tomography (CT) and magnetic resonance imaging (MRI) delineate the exten... | C04 |
9,105 | 3,832 | Anionic complex-carbohydrate units of human thyroglobulin.
Human thyroglobulin (hTG) contains sulfate in chondroitin 6-sulfate chains and in complex carbohydrates.
In this study the sulfate-containing complex carbohydrates were characterized by the number of sulfate and sialic acid residues that they contain.
Sample... | C04 |
9,106 | 9,619 | The relationship of "high risk" mammographic patterns to histological risk factors for development of cancer in the human breast.
In the UK Trial for the Early Detection of Breast Cancer in Nottingham, 119 women were identified as having fibrocystic change with epithelial hyperplasia or in situ carcinoma.
Their mammo... | C04 |
9,107 | 7,052 | Flow cytometric DNA content of adenoid cystic carcinoma of submandibular gland. Correlation of histologic features and prognosis.
Flow cytometric analysis of nuclear DNA content was performed in 26 adenoid cystic carcinomas of the submandibular gland using archived, paraffin-embedded tissues.
The DNA content was comp... | C04 |
9,108 | 5,860 | Sixty consecutive breast reconstructions with the inflatable expander: a critical appraisal.
Breast reconstruction using inflatable expanders has become an established and preferred technique.
Although our knowledge of the biomechanical changes occurring in expanded skin has increased greatly, little information is a... | C04 |
9,109 | 7,427 | Reasons why mastectomy patients do not have breast reconstruction.
Breast reconstruction after mastectomy is valuable, yet only a small percentage of eligible patients ever have reconstruction.
Little has been done to determine why so few patients proceed with reconstructive surgery.
A homogeneous population of mast... | C04 |
9,110 | 5,032 | Local recurrence and survival following nerve-sparing radical cystoprostatectomy.
From March 1982 through July 1988, 76 men underwent nerve-sparing radical cystoprostatectomy for carcinoma of the bladder at our hospital.
Of the 76 patients 2 (2.6%) had positive surgical margins (dome of the bladder and left ureter) a... | C04 |
9,111 | 5,559 | Experience with photocoagulation in Behcet's disease.
Between 1973 and 1987 we examined both eyes of 300 patients with the uveoretinitis-type lesions characteristic of Behcet's disease.
Of the 556 eyes whose fundus could be examined, 38 eyes (6.8%) in 33 patients (11%) had developed retinal capillary nonperfusion, br... | C04 |
9,112 | 8,295 | Carcinosarcoma and spindle cell carcinoma of the lung. Clinicopathologic and immunohistochemical studies.
We examined pulmonary carcinomas with prominent sarcoma-like lesions both clinicopathologically and immunohistochemically.
Grossly, two tumors had predominantly endobronchial growths, four bulky parenchymal growt... | C04 |
9,113 | 9,252 | When is polypectomy sufficient treatment for colorectal cancer in a polyp?
Eighty-seven patients with a carcinoma in a polyp were reviewed over a 12-year period.
Ten histologic criteria were analyzed for an association with the presence of residual carcinoma.
Four factors were identified as having prognostic value: ... | C04 |
9,114 | 9,971 | Adenocarcinoma of the urachus associated with elevated levels of CA 125.
Adenocarcinoma of the urachus is a rare genitourinary tumor with a poor prognosis.
The treatment of choice is en bloc surgical resection, although combination therapy with surgery and chemotherapy has been used with mixed results.
We describe a... | C04 |
9,115 | 7,445 | Metabolism of human gliomas: assessment with H-1 MR spectroscopy and F-18 fluorodeoxyglucose PET
Localized hydrogen-1 magnetic resonance (MR) spectroscopy and fluorine-18 fluorodeoxyglucose (FDG) positron emission tomography (PET) were employed to obtain metabolic information from intracranial gliomas.
Advantages an... | C04 |
9,116 | 2,233 | Low incidence of asymptomatic brain metastases in patients with renal cell carcinoma.
Brain metastases from renal cell carcinoma are uncommon.
The present study was undertaken to determine the value of routine computerized tomographic (CT) scanning of the brain in patients with renal cell carcinoma.
A review of 106 ... | C04 |
9,117 | 2,009 | Rectal carcinoma: CT staging with water as contrast medium.
Computed tomography (CT) was used to study 42 patients with rectal carcinoma.
Water was used as a contrast medium for studying the local extent of tumor in all patients.
Scans were read prospectively without knowledge of the histologic staging and then comp... | C04 |
9,118 | 9,996 | Total bladder replacement using detubularized sigmoid colon: technique and results.
We performed total bladder replacement with a detubularized segment of sigmoid colon in patients after cystoprostatectomy.
The surgical technique and long-term results in 27 patients are reported.
This neobladder configuration compar... | C04 |
9,119 | 4,533 | Insulinoma after streptozotocin therapy for metastatic gastrinoma: natural history or iatrogenic complication?
Islet cell carcinoma frequently produces more than one chemical product, although its clinical expression is usually restricted to a single hormone.
We describe an unusual patient who presented with full-blo... | C04 |
9,120 | 2,423 | Clinical significance of colonic fermentation.
Recent evidence of the potential benefits of short chain fatty acids has prompted renewed interest in the area of human colonic fermentation.
This paper reviews the clinical and metabolic consequences of colonic fermentation. | C04 |
9,121 | 590 | Endoscopic retrograde brush cytology. A new technique.
Endoscopic retrograde cholangiopancreatography has been shown to be a very valuable adjunct in the diagnosis of malignancy involving the biliary and/or pancreatic ductal system.
However, characteristic endoscopic retrograde cholangiopancreatography radiographic f... | C04 |
9,122 | 6,759 | Risk for colon adenomas in patients with rectosigmoid hyperplastic polyps
OBJECTIVE: To determine whether hyperplastic polyps found in the rectosigmoid area of the colon are associated with proximal adenomas, and to judge whether patients with distal hyperplastic polyps found during sigmoidoscopy might benefit from f... | C04 |
9,123 | 8,982 | Matched group study of surgical resection versus cobalt-60 plaque radiotherapy for primary choroidal or ciliary body melanoma.
We report the results of a nonrandomized, matched-group, survival and visual preservation study of patients with a choroidal or ciliary body melanoma managed by microsurgical resection of the ... | C04 |
9,124 | 2,378 | Characterization of the morphonuclear features and DNA ploidy of typical and atypical carcinoids and small cell carcinomas of the lung.
The authors analyzed several cytomorphonuclear parameters related to chromatin distribution and DNA ploidy in typical and atypical carcinoids and in small cell lung cancers.
Nuclear ... | C04 |
9,125 | 428 | Palliative operations for colorectal cancer.
A review of 96 consecutive patients who underwent palliative surgery for primary colorectal cancer was undertaken to clarify the value of palliation achieved with surgical treatment.
The overall rate of postoperative mortality was 8 percent (8 of 96) and the overall rate o... | C04 |
9,126 | 7,187 | Potent toxicity of 2-chlorodeoxyadenosine toward human monocytes in vitro and in vivo. A novel approach to immunosuppressive therapy.
Lymphoid cells were thought to be uniquely susceptible to excess 2'-deoxyadenosine (dAdo), when exposed to inhibitors of adenosine deaminase (ADA).
However, we now find that human mono... | C04 |
9,127 | 5,483 | Suprasellar pituitary adenoma arising from the pars tuberalis: case report.
A rare case of suprasellar pituitary adenoma arising from the pars tuberalis in a 53-year-old woman is presented.
The tumor was located exclusively above the diaphragma sellae, and no invasion into the sella turcica was noted. | C04 |
9,128 | 7,512 | Therapeutic dilemmas associated with antenatally detected ovarian cysts.
Fifteen instances of ovarian cysts detected antenatally are reported.
Seven cysts more than 5 centimeters in diameter were treated surgically because of clinical signs, such as palpable abdominal mass, vomiting and abdominal distension.
Seven c... | C04 |
9,129 | 5,055 | Nuclear morphometry as a prognostic indicator for genitourinary rhabdomyosarcoma: a preliminary investigation.
Rhabdomyosarcoma of the urogenital tract is a malignant mesenchymal tumor seen primarily in childhood.
Multimodal therapy, encompassing surgery, radiotherapy and chemotherapy, has dramatically improved the s... | C04 |
9,130 | 5,805 | Introduction of nerve growth factor (NGF) receptors into a medulloblastoma cell line results in expression of high- and low-affinity NGF receptors but not NGF-mediated differentiation.
Expression of the cloned human nerve growth factor receptor (NGFR) cDNA in cell lines can generate both high- and low-affinity binding... | C04 |
9,131 | 3,337 | Malignant left-sided large bowel obstruction managed by subtotal/total colectomy.
Of 60 patients presenting with acute obstructing carcinoma of the left colon, 49 underwent immediate resection either by radical subtotal/total colectomy (31 patients, group I) or by radical segmental resection (18 patients, group II) of... | C04 |
9,132 | 8,229 | Osteoma of the middle ear.
Osteomas involving the middle ear and causing a functional disturbance are rare.
We report a case of a patient with an osteoma arising from the lateral semicircular canal.
The main symptom was vertigo and to halt this the defect of the canal was obliterated with a bone chip and fibrin glue... | C04 |
9,133 | 4,800 | High- versus standard-dose megestrol acetate in women with advanced breast cancer: a phase III trial of the Piedmont Oncology Association.
One hundred seventy-two patients with advanced breast cancer were randomized to receive oral standard-dose megestrol acetate (MA), 160 mg/d or high-dose MA, 800 mg/d.
All but two ... | C04 |
9,134 | 5,813 | Molecular structure of a major insulin/mitogen-activated 70-kDa S6 protein kinase.
The molecular structure of a rat hepatoma 70-kDa insulin/mitogen-stimulated S6 protein kinase, obtained by molecular cloning, is compared to that of a rat homolog of the 85-kDa Xenopus S6 protein kinase alpha; both kinases were cloned f... | C04 |
9,135 | 7,587 | Multiple myeloma and acute megakaryoblast leukemia in spent phase polycythemia vera.
The spontaneous and simultaneous occurrence of multiple myeloma and megakaryoblast leukemia with myelodysplastic features in a case of spent phase polycythemia vera is well documented.
In support of the morphologic characteristics of... | C04 |
9,136 | 5,460 | Epidermoid tumors of the 4th ventricle: report of seven cases.
Epidermoid tumors occur very rarely in the 4th ventricle.
We discuss the history, clinical course, and the surgical results for seven patients.
One patient had a remittal of symptoms, probably due to the emergence of the tumor from the 4th ventricle into... | C04 |
9,137 | 2,575 | Vitrectomy retinotomy aspiration biopsy of choroidal tumors
We used an investigational technique for the biopsy of intraocular tumors to aid in the diagnosis of three choroidal tumors.
A three-port trans-pars plana vitrectomy was performed in conjunction with retinotomy, tumor biopsy, endophotocoagulation, and air-f... | C04 |
9,138 | 7,365 | A palmar dermatosis linked to occult carcinoma of the upper thorax, head and neck: Bazex's syndrome and tripe palm.
An unusual, persistent, corregated-to-honeycombed thickening of the palms accompanied by tenderness around the fingernails was found to be a cutaneous marker for internal malignancy.
This combination of... | C04 |
9,139 | 5,039 | Erythrocyte polyamine levels in human prostatic carcinoma.
Abnormally high red blood cell polyamine levels were found in benign prostatic hyperplasia and in prostatic adenocarcinoma patients.
In prostatic adenocarcinoma patients a relationship was noted between the importance of red blood cell spermidine and spermine... | C04 |
9,140 | 7,538 | Computed tomography and bronchoscopy in chest radiographically occult main-stem neoplasm diagnosis and Nd-YAG laser treatment in 8 patients.
We studied 8 adult patients with variable symptoms of cough, dyspnea, stridor, wheezing, or hemoptysis.
Fiberoptic bronchoscopy in all showed complete or nearly complete endobro... | C04 |
9,141 | 417 | Multicentric endobronchial granular cell myoblastoma.
Granular cell myoblastoma (GCM) is a rare benign neoplasm involving the tracheobronchial tree.
It is believed to arise from the Schwann cell.
Four cases of tracheobronchial GCM, all of which were multicentric, are presented and a conservative therapeutic approach... | C04 |
9,142 | 2,394 | Isolation of measles virus in primary rhesus monkey cells from a child with acute interstitial pneumonia who cytologically had giant-cell pneumonia without a rash.
The isolation of measles virus in primary Rhesus monkey kidney cells (PRMK) in patients with documented giant-cell pneumonia who have presented without a r... | C04 |
9,143 | 2,224 | Prostate-specific antigen for staging prior to surgery and for early detection of recurrence after surgery.
The exact usefulness of prostate-specific antigen for staging before radical prostatectomy is still unclear.
Perhaps the marker's most exciting feature is its value in detecting residual disease after radical p... | C04 |
9,144 | 7,485 | Small cell lung cancer: staging with MR imaging.
Small cell lung cancer is an aggressive neoplasm; metastases are detected in two-thirds of patients at diagnosis with use of conventional staging, which includes bilateral bone marrow biopsy, bone scintigraphy, and computed tomography (CT) of the head and abdomen.
In 2... | C04 |
9,145 | 9,056 | v-Ha-ras transgene abrogates the initiation step in mouse skin tumorigenesis: effects of phorbol esters and retinoic acid.
Experimental carcinogenesis has led to a concept that defines two discrete stages in the development of skin tumors: (i) initiation, which is accomplished by using a mutagen that presumably activa... | C04 |
9,146 | 6,489 | Immunocytochemical localization of progesterone receptors in endocrine cells of the human pancreas.
Progesterone receptors (PgR) have been immunocytochemically localized in the nuclei of several (40% to 75%) endocrine cells of the human pancreas and in a more variable number of neoplastic cells of 7 of 18 endocrine pa... | C04 |
9,147 | 6,872 | Mediastinal hibernoma, a rare tumor.
Hibernoma is an uncommon soft tissue tumor that is derived from the remnants of fetal brown fat.
Review of the world medical literature revealed 90 cases, 6 of which were intrathoracic.
We present the seventh case of intrathoracic hibernoma; in this case, the hibernoma was within... | C04 |
9,148 | 6,649 | Infection during chronic epidural catheterization: diagnosis and treatment.
A potentially serious complication of long-term epidural catheterization in cancer patients is infection.
The early signs of infection were studied in 350 patients in whom long-term epidural catheters were inserted.
Three areas of the cathet... | C04 |
9,149 | 9,864 | A randomized trial of the effect of three non-steroid anti-inflammatory agents in ameliorating cancer-induced fever.
Paraneoplastic fever is well known, and is not an uncommon problem in daily practice.
In an effort to ameliorate tumour-induced fever we randomized 48 patients to receive three different non-steroid an... | C04 |
9,150 | 6,065 | Decollateralization with silicone rubber sheeting for advanced hepatocellular carcinoma: a preliminary report.
A new treatment method, interception of collaterals with a silicone rubber sheet, was applied to three patients with advanced hepatocellular carcinoma in whom arterial chemoembolization was assessed as ineffe... | C04 |
9,151 | 6,046 | Focal nodular hyperplasia of the liver.
Twenty-four patients underwent biopsy or resection of the liver for focal nodular hyperplasia (FNH) at Memorial Sloan-Kettering Cancer Center from 1978 to 1988.
Twenty-two of the patients were women.
The mean age was 35 years.
A history of antecedent oral contraceptive or con... | C04 |
9,152 | 2,642 | Lymph node metastasis from papillary-follicular thyroid carcinoma in young patients.
A total of 117 patients under 20 years of age with papillary and/or follicular thyroid cancer presented to the M.
D.
Anderson Cancer Center between 1949 and 1987.
The most common presenting symptom was a cervical mass.
Twenty perc... | C04 |
9,153 | 28 | Computed tomography of metastatic cervical lymph nodes. A clinical, computed tomographic, pathologic correlative study.
A retrospective comparative study of 63 neck dissections was undertaken to evaluate further the accuracy of high-resolution computed tomography (CT) in the detection of nodal metastases, as previous ... | C04 |
9,154 | 8,885 | Alterations in opioid parameters in the hypothalamus of rats with estradiol-induced polycystic ovarian disease.
The distribution and density of selectively labeled mu-, delta-, and kappa-opioid binding sites were examined by in vitro radioautography in the hypothalamus of normal, estradiol valerate (EV)-injected, and ... | C04 |
9,155 | 495 | The effect of metoclopramide on ovarian responsiveness to gonadotropin administration in patients with severe polycystic ovarian syndrome.
Six patients with poor ovarian response to menotropin after pretreatment with a gonadotropin-releasing hormone analog exhibited improved ovarian responsiveness when metoclopramide ... | C04 |
9,156 | 4,724 | Laryngeal metastasis from colonic adenocarcinoma.
Metastases to the larynx from distant primaries are very rare.
Usually the secondary lesion comes from an hypernephroma or malignant melanoma.
A case of metastatic laryngeal tumour from a colonic adenocarcinoma, occurring in a 59-year-old woman, is presented and the ... | C04 |
9,157 | 2,016 | Effect of somatostatin analogue (octreotide) on blood flow to endocrine tumors metastatic to the liver: angiographic evaluation.
The effect of an octapeptide analogue of somatostatin, octreotide, on tumor blood flow was evaluated with angiography in eight patients with hepatic endocrine tumors; one patient had primary... | C04 |
9,158 | 4,819 | Pediatric osteosarcoma: therapeutic strategies, results, and prognostic factors derived from a 10-year experience.
Ninety-eight pediatric patients were treated with three separate protocols (Treatment and investigation of Osteosarcoma [TIOS] I, II, and III) and 47 developed recurrent disease (metastases and/or local r... | C04 |
9,159 | 3,388 | Expression of pancreatic secretory trypsin inhibitor gene in human colorectal tumor.
Expression of pancreatic secretory trypsin inhibitor (PSTI) gene was examined by Northern blotting analyses in 31 human colorectal tumors that included two benign adenomas and 26 adenocarcinomas.
Among the total of 28 cases which pro... | C04 |
9,160 | 2,941 | Surgical treatment of cardiac myxomas: long-term results.
Between 1965 and 1988, 22 patients underwent 24 operations for cardiac myxomas.
Two patients had the complex myxoma syndrome.
Mitral valve replacement was required at initial operation in 2 patients.
One patient died perioperatively, and 5 others died subseq... | C04 |
9,161 | 5,755 | Human colorectal cancers display abnormal Fourier-transform infrared spectra.
Fourier-transform infrared spectroscopy (FT-IR) was applied to the study of tissue sections of human colorectal cancer.
Pairs of tissue samples from colorectal cancer and histologically normal mucosa 5-10 cm away from the tumor were obtaine... | C04 |
9,162 | 6,854 | Giant chest wall tumor resulting from tissue reaction to foreign bodies.
Three patients are reported in whom chest wall tumors developed 19 to 28 years after thoracoplasty and increased in size with time.
The tumors could be removed operatively with good results.
All tumors were composed of hematoma and necrotic mat... | C04 |
9,163 | 5,996 | Regulation of gene expression with double-stranded phosphorothioate oligonucleotides.
Alteration of gene transcription by inhibition of specific transcriptional regulatory proteins is necessary for determining how these factors participate in cellular differentiation.
The functions of these proteins can be antagonize... | C04 |
9,164 | 2,583 | Limbal autograft reconstruction after conjunctival squamous cell carcinoma.
Two patients who had squamous cell carcinoma with extensive limbal and corneal involvement were treated with surgery and cryotherapy.
Rarely large areas of the cornea are involved by this tumor.
Visual prognosis in such patients is poor.
In... | C04 |
9,165 | 5,038 | Clinical stage 1 testicular cancer: the role of modified retroperitoneal lymphadenectomy.
A total of 85 patients underwent modified retroperitoneal lymphadenectomy for clinical stage I nonseminomatous germ cell tumor of the testis from 1982 to 1989.
The technique was a modified bilateral dissection via a thoracoabdom... | C04 |
9,166 | 5,499 | Procarbazine chemotherapy in the treatment of recurrent malignant astrocytomas after radiation and nitrosourea failure.
The Brain Tumor Study Group has shown procarbazine (PCB) to be as effective an adjuvant treatment as 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU).
We treated 35 patients with recurrent malignant astr... | C04 |
9,167 | 6,838 | Intrarectal ultrasonography in rectal cancer staging and in the evaluation of pelvic disease. Clinical uses of intrarectal ultrasound.
Accurate preoperative staging of a rectal cancer patient may impact heavily on subsequent management.
This study attempts to evaluate the accuracy of intrarectal ultrasonography (IRUS... | C04 |
9,168 | 7,059 | Metastasizing pleomorphic adenoma of the nasal septum.
Pleomorphic adenoma is the most common benign tumor of glandular tissue occurring in the head and neck region.
There have been several reports of metastasis of this benign-appearing tumor from the salivary glands to distant sites, suggesting hematogenous spread a... | C04 |
9,169 | 8,685 | Use of the levator scapulae muscle flap in head and neck reconstruction.
There are numerous techniques available for reconstruction of defects following composite resection of oral cavity and oropharyngeal tumors.
No single technique is applicable in all situations.
The levator scapulae muscle flap is well known for... | C04 |
9,170 | 4,859 | The potential of 2-deoxy-2[18F]fluoro-D-glucose (FDG) for the detection of tumor involvement in lymph nodes.
To assess the potential of FDG for PET imaging of nodal tumor metastases, we evaluated its uptake into normal lymph nodes, tumor-involved lymph nodes, and subcutaneous tumor xenografts in rodents.
Normal lymph... | C04 |
9,171 | 5,042 | Radical prostatectomy for clinical stage T1-2N0M0 prostatic adenocarcinoma: long-term results.
A total of 441 stage T1-2N0M0 and 11 stage T1-2N0M0 cancer patients with an elevated acid phosphatase level only, and 18 stage T1-2N+M0 cancer patients underwent radical prostatectomy.
Analysis of the 441 stage T1-2N0M0 can... | C04 |
9,172 | 9,627 | Microdochectomy for discharge from a single lactiferous duct.
Microdochectomy for persistent discharge from a single lactiferous duct was performed in 162 women.
Invasive or in situ ductal carcinoma was diagnosed in 16 patients (10 per cent), none of whom had a palpable lump.
The discharge was blood-stained in 14 of... | C04 |
9,173 | 2,108 | Trends in primary breast cancer management. Where are we going?
The treatment of cancer during any period has been based not on the whim of a clinician but on the therapeutic consequences of the dominant biologic model of the disease.
Until the 1960s, the dominant model of breast cancer was of a disease that spread c... | C04 |
9,174 | 6,335 | Adenocarcinoma arising in Barrett's esophagus after total gastrectomy
A 64-yr-old Japanese male who underwent a partial gastrectomy for a duodenal ulcer at the age of 21, a total resection of the remnant stomach for a stomal ulcer at age 25, and in whom Barrett's esophagus was diagnosed at age 47, was found to have a... | C04 |
9,175 | 2,850 | Histopathologic grading of salivary gland neoplasms: I. Mucoepidermoid carcinomas.
Histopathologic grading of salivary gland neoplasms has been done with various degrees of success and hence various degrees of acceptance among pathologists and otolaryngologists-head and neck surgeons.
Given their histopathologic dive... | C04 |
9,176 | 8,130 | New primary basal cell carcinomas arising in skin flaps following Mohs micrographic surgery for primary and recurrent basal cell carcinoma.
Two patients developed new primary basal cell carcinomas (BCCs) in skin flaps used to reconstruct wounds that followed an earlier primary BCC and a recurrent BCC treated by Mohs m... | C04 |
9,177 | 3,426 | Increased expression of the multidrug-resistance gene in undifferentiated sarcoma.
We analyzed multidrug-resistance gene (mdr1 gene) expression in a patient with undifferentiated sarcoma of the liver using the cloned cDNA for the mdr1 gene.
Tissue samples were available at the time of initial diagnosis and of two int... | C04 |
9,178 | 9,677 | The importance of calcium regulation in toxic cell injury. Studies utilizing the technology of digital imaging fluorescence microscopy.
The regulation of ions within the cell is of critical importance in both acute and chronic toxicology.
Recently, new methods have been developed for measuring such changes in living ... | C04 |
9,179 | 5,221 | In vivo selection and characterization of a murine mammary tumor subline with high potential for spontaneous lymph node metastasis.
A transplantable mammary adenocarcinoma, grown in Balb/c mice, with a marked enhancement in its draining lymph node metastatic ability (MM3LN), was obtained through an in vivo procedure f... | C04 |
9,180 | 2,661 | Flow cytometric evaluation of chemosensitive and chemoresistant head and neck tumors.
For patients with head and neck squamous carcinoma, a clinical response to induction chemotherapy has correlated with a survival advantage.
Similarly, patients with diploid tumors have displayed a survival advantage when compared wi... | C04 |
9,181 | 857 | Years of potential life lost: another indicator of the impact of cutaneous malignant melanoma on society.
Years of potential life lost (YPLL) is an indicator of premature mortality that complements traditional incidence and mortality rates and that facilitates comparisons among different cancers.
We calculated YPLL f... | C04 |
9,182 | 5,774 | Adult T-cell leukemia-derived factor/thioredoxin, produced by both human T-lymphotropic virus type I- and Epstein-Barr virus-transformed lymphocytes, acts as an autocrine growth factor and synergizes with interleukin 1 and interleukin 2.
Interleukin 1 (IL-1) has been obtained from the Epstein-Barr virus-infected B-lym... | C04 |
9,183 | 6,025 | Adenocarcinoma of the colon occurring with intussusception in an adolescent.
Hydrostatic reduction of intussusception is definitive therapy in most infants with this abnormality.
In the older child, adolescent, and adult, a polyp or tumor is often present.
Operative intervention should be considered earlier in the c... | C04 |
9,184 | 2,109 | Prognostic indicators in invasive breast cancer.
Tumor size and axillary lymph node involvement are the primary determinants of clinical course for most patients.
Receptors for estrogen and progesterone are important additional prognostic factors for disease-free survival, overall survival, survival time after initia... | C04 |
9,185 | 8,162 | The gastrin hypothesis. Implications for antisecretory drug selection.
Newer potent and long-acting inhibitors of acid secretion, such as the proton pump inhibitor omeprazole, are becoming available for general use.
These drugs promise to control acid-peptic disease effectively in patients who do not respond adequate... | C04 |
9,186 | 5,791 | Homeobox gene expression plus autocrine growth factor production elicits myeloid leukemia.
In the murine myelomonocytic leukemia WEHI-3B, proviral insertions have induced expression of the Hox-2.4 homeobox gene and the gene for the myeloid growth factor interleukin 3 (IL-3).
To assess their potential oncogenic role, ... | C04 |
9,187 | 2,381 | Bcr/abl recombinant DNA analysis versus karyotype in the diagnosis and therapeutic monitoring of chronic myeloid leukemia.
Karyotype and bcr/abl recombinant DNA analyses are two means of detecting the chromosomal aberration in chronic myeloid leukemia.
The authors compared these two methods in a retrospective study o... | C04 |
9,188 | 6,246 | Natural history of cardiac rhabdomyoma in infancy and childhood.
Although spontaneous regression of cardiac rhabdomyoma has been reported, prognosis is still considered to be poor and surgery continues to be indicated.
The experience with rhabdomyoma diagnosed in live infants over a 20-year period was reviewed.
Diag... | C04 |
9,189 | 3,997 | Liver fatty acid-binding protein: a marker for studying cellular differentiation in gut epithelial neoplasms.
Human liver fatty acid binding protein is a 127 residue cytoplasmic protein synthesized in liver and in the intestinal epithelium.
Previous studies of normal and transgenic mice indicated that the liver fatty... | C04 |
9,190 | 3,335 | Urinary tissue factor activity in colorectal disease.
Procoagulant activity (PCA) in normal urine has been recognized for over 50 years.
Although tissue factor (TF) is produced by certain tumours, and is increased in both tumour-associated macrophages and blood monocytes, the possibility that it might also be increas... | C04 |
9,191 | 4,810 | A prospective, randomized evaluation of the treatment of colorectal cancer metastatic to the liver.
Over a 4-year period (1982 to 1986), 91 patients with solitary or multiple metastases from colorectal cancer were stratified, based on findings at laparotomy, to one of three groups and then prospectively randomized to ... | C04 |
9,192 | 5,217 | Neoadjuvant Cis-DDP in esophageal cancers: an experience at a regional cancer centre, India.
We are analysing the results of 80 patients who underwent surgery during 1983-84 for esophageal cancer.
Forty patients who received pre-operative single agent Cis-DDP were grouped under "A" and 40 patients who went for surger... | C04 |
9,193 | 8,794 | Primary central nervous system lymphoma in a pediatric patient with acquired immune deficiency syndrome. Treatment with radiation therapy.
Primary central nervous system (CNS) lymphoma, an otherwise rare pediatric tumor, has been reported with increasing frequency in children with acquired immune deficiency syndrome (... | C04 |
9,194 | 3,634 | Chondrosarcoma complicating total hip arthroplasty in Maffucci's syndrome.
A 70-year-old woman who was followed for 60 years for Maffucci's syndrome required a total hip arthroplasty (THA) of the right hip for degenerative arthritis.
This did not relieve pain.
Three years later, chondrosarcoma of the femur developed... | C04 |
9,195 | 3,414 | Chemotherapy-related hemolytic-uremic syndrome after the treatment of head and neck cancer. A case report.
A 62-year-old woman who was being treated for squamous cell carcinoma of the head and neck developed a chemotherapy-related hemolytic-uremic syndrome during the second cycle of neoadjuvant chemotherapy consisting... | C04 |
9,196 | 9,787 | Occurrence of human papillomavirus type 16 DNA in cutaneous squamous and basal cell neoplasms.
Sixty-eight cutaneous squamous cell neoplasms (in situ and invasive) and 26 basal cell carcinomas from 89 patients were analyzed for DNA sequences homologous to the human papillomavirus (HPV) types found predominantly in the... | C04 |
9,197 | 6,153 | Radiologic staging of chest in testicular seminoma.
We investigated the usefulness of chest x-ray (CXR), conventional planar tomography (TOM), and computerized axial tomography (CAT) in evaluating patients with Stages I and II testicular seminoma.
All patients had a CXR, and 22 patients had either TOM or CAT as part ... | C04 |
9,198 | 2,999 | The technicon H6000 analyzer discriminates chronic lymphocytic leukemia from other B-cell leukemias through automatic assessment of large unstained cells.
The separation of chronic lymphocytic leukemia of B-cell origin from other chronic B-cell leukemias is subjective, being largely based on the morphologic features o... | C04 |
9,199 | 6,314 | Primary malignant melanoma of the lower respiratory tract. Report of a case and literature review.
The authors report a case of primary bronchial malignant melanoma, occurring in a 34-year-old woman presenting with persistent cough.
At bronchoscopic examination, a polypoid mass was found to occlude the left mainstem ... | C04 |
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