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10.1016/j.jpeds.2009.01.015 | Medicine_364 | In other words, among overweight and obese kids, a doubling of sodium intake was associated with a 3 percent increase in systolic blood pressure. | At the same time, the P value for trend in the sugar-sweetened beverages and systolic blood pressure association is very close to the conventional threshold for statistical significance so it is possible that this is a false positive association due to chance. | (The two groups' average diastolic pressures, the bottom number in the ratio, were the same.) In other words, among overweight and obese kids, a doubling of sodium intake was associated with a 3 percent increase in systolic blood pressure. An average systolic blood-pressure difference of 3 percent could, however, have ... | This misclassification bias may also diminish the observed effect size of the sugar-sweetened beverage consumption and systolic blood pressure association. At the same time, the P value for trend in the sugar-sweetened beverages and systolic blood pressure association is very close to the conventional threshold for sta... | [1.0, 3.0, 1.0, 1.0, 1.0] | Medicine | train | 1.4 | news | http://www.scientificamerican.com/article.cfm?id=what-science-on-hypertension-really-shows |
10.1093/gerona/glt162 | Medicine_365 | So, the "work longer" strategy might be physically possible for large numbers of older people. | Our findings suggest that the time has arrived to reconsider the importance of chronological age and to design better social policies to reflect the substantial variation in health trajectories across the life span. | Based on this data, it's probably safe to say that roughly eight out of 10 people in their late 60s are healthy enough to work in some capacity, roughly three-fourths of people in their 70s could work and maybe half of those in their early 80s could work. So, the "work longer" strategy might be physically possible for ... | Instead, different people appear to be experiencing widely different health trajectories with widely different health outcomes at the same ages. Our findings suggest that the time has arrived to reconsider the importance of chronological age and to design better social policies to reflect the substantial variation in h... | [3.0, 1.0, 4.0, 1.0] | Medicine | train | 1 | news | http://www.cbsnews.com/news/how-long-could-you-delay-retirement/ |
10.1126/science.1252496 | Medicine_366 | While the samples are suspected to be from beyond the solar system, he says, potential confirmation of their origin must come from subsequent tests that will ultimately destroy some of the particles. | The residues of the particles captured in the Al foil appear to be amorphous, but whether this is an original feature or an effect of hypervelocity capture alteration is unclear. | All analysis was non-destructive, meaning that it preserved the structural and chemical properties of the particles. While the samples are suspected to be from beyond the solar system, he says, potential confirmation of their origin must come from subsequent tests that will ultimately destroy some of the particles. "Th... | This hypothesis may be testable by a future measurement of the isotopic composition of oxygen. The residues of the particles captured in the Al foil appear to be amorphous, but whether this is an original feature or an effect of hypervelocity capture alteration is unclear. Three of the four craters contain sulfides, wh... | [3.0, 2.0, 2.0, 1.0, 5.0] | Medicine | train | 2 | news | http://www.nanowerk.com/news2/space/newsid=37140.php |
10.1016/j.neuron.2018.12.026 | Medicine_367 | Increased Excitation-Inhibition Ratio Stabilizes Synapse and Circuit Excitability in Four Autism Mouse Models. | The results above suggest that despite substantial loss of inhibition, L2/3 spike rate may be relatively unchanged or even reduced in vivo. | Note: material may have been edited for length and content. For further information, please contact the cited source. Increased Excitation-Inhibition Ratio Stabilizes Synapse and Circuit Excitability in Four Autism Mouse Models. | The only exception was a non-significant trend toward reduced, not increased, PSP amplitude in Fmr1 À/y mice near spike threshold ( Figures 4E and 4F ). The results above suggest that despite substantial loss of inhibition, L2/3 spike rate may be relatively unchanged or even reduced in vivo. Spontaneous spiking of L2/3... | [2.0, 2.0, 1.0] | Medicine | train | 1.666667 | news | http://ct.moreover.com/?a=38318437455&p=1pl&v=1&x=tFlh-_qIVNCNf8CEol-uvQ |
10.1038/s41591-018-0091-x | Medicine_368 | The results revealed that two particular enhancers, regulating SLC9A3R1 and Yin Yang 1 genes, are activated at specific stages when they might help cancer cells grow and evade treatment. | YY1positive cells appear to dominate both primary and metastatic lesions in luminal patients, suggesting that this might remain important even after ET ( Fig. | The cancer might have changed significantly in this time, and would respond to different treatments. The results revealed that two particular enhancers, regulating SLC9A3R1 and Yin Yang 1 genes, are activated at specific stages when they might help cancer cells grow and evade treatment. In particular Yin Yang1 was foun... | YY1 contributes to endocrine resistance in luminal BC. YY1positive cells appear to dominate both primary and metastatic lesions in luminal patients, suggesting that this might remain important even after ET ( Fig. Interestingly, LTED cells have an expanded repertoire of ERα binding compared to MCF7, fuelled by endogeno... | [2.0, 2.0, 3.0, 4.0] | Medicine | train | 2.75 | news | http://ct.moreover.com/?a=34627030168&p=1pl&v=1&x=hF9k2ZTU-XUiToM72b9JHA |
10.1073/pnas.1408439111 | Medicine_369 | When this information is repeated multiple times, over millions of users, we can extract a detailed picture of population density and how it changes over time in a given area." | Applying the approach to countries such as the DRC, where reliable training data may not be available, requires some adjustments and assumptions, particularly regarding the relation between the MP user density and the population density, through estimates for the parameters α and β. | However, anonymous phone data can be examined regularly to map daily, weekly or monthly changes across an entire country, at less cost and with greater flexibility. When this information is repeated multiple times, over millions of users, we can extract a detailed picture of population density and how it changes over t... | Even if at present the most remote and isolated populations may not have reception in some low-income countries, possibly affecting the ability to produce a comprehensive countrywide map, network coverage continues to grow at a rapid rate everywhere. Applying the approach to countries such as the DRC, where reliable tr... | [2.0, 4.0, 1.0, 3.0] | Medicine | train | 2.5 | news | http://www.sciencedaily.com/releases/2014/10/141028082456.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 |
10.1001/jama.2018.20578 | Medicine_37 | The use of aspirin in patients without cardiovascular disease was associated with increased risk of major bleeding. | The current study demonstrates that the absolute risk reduction for cardiovascular events and absolute risk increase for major bleeding associated with aspirin use were of similar magnitude. | In this systematic review and meta-analysis, while aspirin use among patients without cardiovascular disease was associated with fewer adverse cardiovascular events, it was not associated with a reduction in all-cause mortality. The use of aspirin in patients without cardiovascular disease was associated with increased... | 6 This study showed that when analysis was restricted to populations with observation-derived 10-year cardiovascular event rate estimates of 10% or more, aspirin use was associated with an absolute risk decrease of 0.51% (5% CI, 0.06%-0.3%) for the cardiovascular composite outcome, but an absolute risk increase of 0.64... | [2.0, 4.0, 3.0, 2.0, 3.0] | Medicine | train | 2.8 | news | http://ct.moreover.com/?a=38328030969&p=1pl&v=1&x=7e7iZH1GB8Gg-5kdEyEhYQ |
10.3945/an.111.000513 | Medicine_370 | Eating apples can increase the production of saliva in the mouth, eliminating bacteria and food particles. | AP might be protective because of their antioxidant potential and phytochemical content. | Better oral health
Alkaline foods can help promote acidic balance, and apples just happen to be a great alkaline fruit. Eating apples can increase the production of saliva in the mouth, eliminating bacteria and food particles. This can help in reducing the risk of bad breath. | If these findings are applicable to the in vivo situation, altered intestinal lipid secretion might account for the lipid-lowering effect of AP observed in some studies and suggest one possible mechanism for reduced risk of cardiovascular disease. AP might be protective because of their antioxidant potential and phytoc... | [1.0, 1.0, 1.0] | Medicine | train | 1 | news | http://ct.moreover.com/?a=35001604984&p=1pl&v=1&x=gj9dPxhyqwLYLECDqTxsew |
10.1038/s41598-018-35253-2 | Medicine_371 | This demonstrates the methane must be sourced from beneath the glacier," Dr Wynn explains. | Extensive potential for methanotrophic activity, as evidenced through the incubation of sediments under oxidizing conditions (see Supplementary Fig. | "The highest concentrations were found at the point where the river emerges from underneath the glacier and enters the lake. This demonstrates the methane must be sourced from beneath the glacier," Dr Wynn explains. But there is still a connection with the volcano. | As the most enriched values exceed the geogenic range, the observed isotopic signatures cannot be explained by a mixture of biogenic and geogenic methane (Fig. Extensive potential for methanotrophic activity, as evidenced through the incubation of sediments under oxidizing conditions (see Supplementary Fig. S2 ), likel... | [2.0, 1.0, 1.0, 2.0] | Medicine | train | 1.5 | news | http://ct.moreover.com/?a=37746306455&p=1pl&v=1&x=Jqs7WivP4DGVbjXdDvLl4g |
10.1136/injuryprev-2013-040923 | Medicine_372 | "While pedestrian deaths are more common in many parts of Africa, motorcycle and bicycle deaths occur more frequently in southeast Asia. | 4 Baker et al showed that infectious diseases made up only 1% of traveller deaths, despite being a prominent focus for travel clinics and government agencies working to reduce risk abroad. | "While pedestrian deaths are more common in many parts of Africa, motorcycle and bicycle deaths occur more frequently in southeast Asia. One limitation of the study, which the authors acknowledge, is that we still do not know the characteristics of people who travel to different countries." Out of all the countries dee... | However, this information cannot be used to effectively communicate risk information because it does not account for the number of outbound trips to the countries of interest. 4 Baker et al showed that infectious diseases made up only 1% of traveller deaths, despite being a prominent focus for travel clinics and gover... | [1.0, 1.0, 1.0, 1.0, 1.0] | Medicine | train | 1 | news | http://www.medicaldaily.com/road-crashes-1-killer-americans-abroad-more-us-citizens-died-car-or-motorcycle-accidents-terrorist |
10.1016/j.cmet.2015.02.003 | Medicine_373 | Salt increased the microbe-killing capacity of the immune cells, the team reports; the macrophages exposed to high levels of sodium chloride released significantly more microbicidal molecules than those that grew in a culture medium without salt. | Activation of macrophages in the presence of high NaCl concentrations modified epigenetic markers and enhanced p38 mitogen-activated protein kinase (p38/MAPK)-dependent nuclear factor of activated T cells 5 (NFAT5) activation. | Titze and his colleagues realized that immune cells arriving in wounded skin to fight infections were entering a salty microenvironment. Salt increased the microbe-killing capacity of the immune cells, the team reports; the macrophages exposed to high levels of sodium chloride released significantly more microbicidal m... | We found that Na + accumulated at the site of bacterial skin infections in humans and in mice. Activation of macrophages in the presence of high NaCl concentrations modified epigenetic markers and enhanced p38 mitogen-activated protein kinase (p38/MAPK)-dependent nuclear factor of activated T cells 5 (NFAT5) activation... | [4.0, 5.0, 4.0, 3.0, 3.0] | Medicine | train | 3.8 | news | http://news.sciencemag.org/biology/2015/03/does-high-salt-diet-combat-infections |
10.1038/s41467-018-04355-w | Medicine_374 | They saw a significant decrease in lung metastases. | Specifically, y = 9 when this ratio is the highest and y = 1 when this ratio is the lowest. | The researchers were able to reduce metastases by using a compound that blocks CCR2, a receptor on the surface of the inflammatory monocytes. They saw a significant decrease in lung metastases. Pecot said they want to continue investigating this strategy, and potentially other ways of preventing clotting within tumors,... | Clearly, this heatmap/matrix a i,j is symmetrical with respect to its main diagonal (a i*,j* = a j*,i* ). Specifically, y = 9 when this ratio is the highest and y = 1 when this ratio is the lowest. Notably, HR > 1 for each of these nine cell types, since when their density is "high" the prognosis, collectively speaking... | [1.0, 1.0, 2.0, 1.0] | Medicine | train | 1.25 | news | http://healthmedicinet.com/news/by-forming-clots-in-tumors-immune-cell-aids-lung-cancers-spread/ |
10.1007/s00213-014-3810-0 | Medicine_375 | / no comments
These Bacteria Could Be The Leading Cause Of Your Anxiety -- And Other Issues
Your gut feeling could be causing your anxiety. | There were no associations of cortisol with attentional performance (all p>0.1). | / no comments
These Bacteria Could Be The Leading Cause Of Your Anxiety -- And Other Issues
Your gut feeling could be causing your anxiety. There is a connection between anxiety and an upset gut. In the study, when the bacteria's healthy functions were restored, mood and behavior leveled out, reducing or eliminating ... | Furthermore, there were no group differences in the overall cognitive status as assessed by digit span on the day of psychological testing. There were no associations of cortisol with attentional performance (all p>0.1). Results revealed that B-GOS prebiotic intake was associated with decreased waking salivary cortisol... | [1.0, 3.0, 1.0] | Medicine | train | 1.666667 | news | http://healthmedicinet.com/news/can-bacteria-cause-anxiety/ |
10.1038/s41598-017-18618-x | Medicine_377 | This study administered 30 cc of ACV per day and found that it created significantly reduced body weight, BMI, hip-circumference, visceral adiposity index, and appetite score. | Figure 3 depicts the effects of a dose dependent reduction in TNFα and IL-6 release from monocytes which have been co-cultured with ACV, together with either C. albicans, E-coli or S. aureus for 24 h. | This study administered 30 cc of ACV per day and found that it created significantly reduced body weight, BMI, hip-circumference, visceral adiposity index, and appetite score. In addition, plasma triglycerides and total cholesterol levels were decreased and HDL (good lipids) was increased in the ACV group. Weight check... | Both sets of results were also confirmed further by microdilution. Figure 3 depicts the effects of a dose dependent reduction in TNFα and IL-6 release from monocytes which have been co-cultured with ACV, together with either C. albicans, E-coli or S. aureus for 24 h. Consistent with the microbial growth inhibition data... | [2.0, 1.0, 1.0, 2.0] | Medicine | train | 1.5 | news | http://ct.moreover.com/?a=39098464353&p=1pl&v=1&x=1oF0R8OHMp2RCFFanDJNtw |
10.1016/j.mayocp.2014.07.004 | Medicine_378 | "As far as we are aware, our study is the first prospective cohort study comparing prescription medication when offered with specialist behavioral support with prescription medication offered without such support. | The use of NRT bought over the counter was associated with a lower odds of abstinence (odds ratio, 0.68; 95% CI, 0.49-0.94). | A combination of prescription medication along with limited behavioral support was also more effective than unaided quitting. "As far as we are aware, our study is the first prospective cohort study comparing prescription medication when offered with specialist behavioral support with prescription medication offered wi... | Results: Compared with smokers using none of the cessation aids, the adjusted odds of remaining abstinent up to the time of the 6-month follow-up survey were 2.58 (95% CI, 1.48-4.52) times higher in users of prescription medication in combination with specialist behavioral support and 1.55 (95% CI, 1.11-2.16) times hig... | [2.0, 2.0, 1.0, 1.0] | Medicine | train | 1.5 | news | http://www.sciencedaily.com/releases/2014/10/141008083514.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29 |
10.1038/s41467-019-09863-x | Medicine_379 | But they are considerably lower for these scenarios compared to business as usual," said Yumashev. | For the PCF, the legacy value is zero emissions from permafrost since the PCF is not included in most climate projections using GCMs 18 . | "Even at 1.5degC to 2degC [warming], there are impacts and costs due to thawing permafrost. But they are considerably lower for these scenarios compared to business as usual," said Yumashev. "The most important thing to remember about our study is the greater the warming, the stronger the feedbacks and the higher the c... | Figure 3 shows the medians and 25-75% ranges for the GMST projections relative to pre-industrial levels for the climate scenarios considered, obtained using PAGE-ICE with the legacy values of the PCF and SAF. For the PCF, the legacy value is zero emissions from permafrost since the PCF is not included in most climate p... | [1.0, 1.0, 1.0, 1.0] | Medicine | train | 1 | news | http://ct.moreover.com/?a=39059198716&p=1pl&v=1&x=LFeOjGrAvD1wF12D7W6Wvg |
10.1073/pnas.1504869112 | Medicine_38 | Extrapolating their results to tropical forests as a whole, the team calculated that lianas could potentially reduce long-term storage of carbon in tropical forests by one-third or more. | This study is the first direct demonstration of liana effects at the ecosystem scale and illustrates the important role of lianas in tropical forests, particularly with respect to carbon budgets. | The researchers found that study plots with lianas accumulated 76 percent less biomass over the experimental period due to reduced tree growth and increased tree death. Extrapolating their results to tropical forests as a whole, the team calculated that lianas could potentially reduce long-term storage of carbon in tro... | By impacting on tree growth and survival, lianas impact the carbon balance of these forests. This study is the first direct demonstration of liana effects at the ecosystem scale and illustrates the important role of lianas in tropical forests, particularly with respect to carbon budgets. Lianas are increasing in biomas... | [3.0, 5.0, 5.0, 4.0] | Medicine | train | 4.25 | news | http://feedproxy.google.com/~r/TechnologyOrg/~3/PUyOGba13Ho/ |
10.1186/gb-2013-14-7-r73 | Medicine_380 | Importantly, removal of these RNAs causes the death of cancer cells providing a clear direction for the development of therapeutics and better diagnostics for cancer patients. | It's tantalizing to speculate that these RNAs could participate in the complex machinery that supports the pluripotent-like properties of cancerous cells. | Researchers found that some of these vlincRNAs are co-opted by cancer-associated transcriptional programs. Importantly, removal of these RNAs causes the death of cancer cells providing a clear direction for the development of therapeutics and better diagnostics for cancer patients. VlincRNAs may contribute to the regul... | In this respect, it's reminiscent of very recent studies showing the prominent importance of cancer stem cells in disease . It's tantalizing to speculate that these RNAs could participate in the complex machinery that supports the pluripotent-like properties of cancerous cells. Here we provide evidence that these cellu... | [3.0, 3.0, 1.0, 1.0, 2.0] | Medicine | train | 2 | news | http://www.sciencedaily.com/releases/2013/07/130731093915.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29 |
10.1001/jamaophthalmol.2017.4655 | Medicine_381 | For each BCVA criterion, the total annual incidence was 12.4 percent of the total prevalence. | If the death rate has been underestimated for the LV population, then the annual LV incidence rate also has been underestimated. | The researchers found that among older adults (>=45 years) in 2017, the prevalence of low vision and blindness was estimated at 3,894,406 individuals with a best corrected visual acuity (BCVA) less than 20/40, 1,483,703 individuals with a BCVA less than 20/60, and 1,082,790 individuals with a BCVA of 20/200 or less. Fo... | 17 In addition, it is possible, if not probable, that LV increases death rates because LV increases the risk of falls, 18-22 medication mismanagement, 24 and reduced activity levels. If the death rate has been underestimated for the LV population, then the annual LV incidence rate also has been underestimated. The risk... | [1.0, 1.0, 1.0, 1.0] | Medicine | train | 1 | news | http://www.physiciansbriefing.com/Article.asp?AID=728151 |
10.1098/rsos.150710 | Medicine_382 | "The findings suggest it's not so easy to increase good behaviour using online cues such as images, and that's an interesting finding given the level of interest in looking at how we behave online and what might influence online behaviour," he says. | This work supports the importance of cultural differences and enduring individual differences in prosocial behaviour and shows that a range of artificial monitoring cues do not reliably boost online charity donation on MTurk. | Study co-author Associate Professor Quentin Atkinson says none of the 'monitoring cues' such as human faces or simply a pair of watching eyes, worked to increase donations. "The findings suggest it's not so easy to increase good behaviour using online cues such as images, and that's an interesting finding given the lev... | By contrast, the control variables of culture, age, sex and previous charity giving frequency did predict donations. This work supports the importance of cultural differences and enduring individual differences in prosocial behaviour and shows that a range of artificial monitoring cues do not reliably boost online char... | [3.0, 2.0, 4.0] | Medicine | train | 3 | news | http://healthmedicinet.com/news/do-online-tools-change-online-behaviour/ |
10.1098/rspb.2013.3172 | Medicine_383 | According to Professor Bauch, as that trend continues Canadians will increasingly find themselves in a situation where vaccination coverage has declined and populations are once again susceptible to disease. | Viewed from this perspective, the whole-cell pertussis vaccine scare of the 1970s interrupted an otherwise steady climb in vaccine coverage that was converging towards the E 1 equilibrium. | Obviously, when enough parents are no longer vaccinating, the disease will come back." According to Professor Bauch, as that trend continues Canadians will increasingly find themselves in a situation where vaccination coverage has declined and populations are once again susceptible to disease. "Parents are not cold, cl... | The long-term effects of the scare are apparent in the continued discrepancy between vaccine coverage with and without the scare as late as 2010, which is 30 years after perceived vaccine risk was modelled to have returned to baseline levels. Viewed from this perspective, the whole-cell pertussis vaccine scare of the 1... | [2.0, 4.0, 2.0, 4.0] | Medicine | train | 3 | news | http://www.sciencedaily.com/releases/2014/02/140214111211.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 |
10.1001/jamapsychiatry.2015.0500 | Medicine_387 | In 2010, it began at 0.11 percent among ages 1 to 6. | In the community, the prevalence of adolescents with severe impairment is 8.7% for depression, 4.3% for ADHD, and 2.6% for bipolar disorder. | The percentage dropped to about half a percent by the time they reach the age of 19. In 2010, it began at 0.11 percent among ages 1 to 6. Then it increased to 0.80 percent among ages 7 to 12. | 41 In our study, among adolescents treated with antipsychotics who had diagnosed psychiatric disorders, the most common diagnoses were ADHD (34.9%), followed by depression (24.4%) and bipolar disorder (20.5%). In the community, the prevalence of adolescents with severe impairment is 8.7% for depression, 4.3% for ADHD, ... | [1.0, 2.0, 2.0, 1.0, 2.0] | Medicine | train | 1.6 | news | http://www.techtimes.com/articles/65576/20150702/boys-with-adhd-more-likely-to-be-given-antipsychotics-study.htm |
10.1126/science.aat9688 | Medicine_388 | The team hopes that their new technique will open the door for lots of new experiments and discoveries at the nanoscale, thanks to the options that it provides for the first time. | The STM tunneling current, however, can generate excited states of a molecule and hence give enhanced specificity, and more varied outcomes, to the manipulation action [e.g., bond dissociation (4, 5) , isomerization (6), or tautomerization (7) ]. | Essentially we have a new dial we can set when running our experiment. The extreme nature of working on these scales makes it hard to do, but we have extreme resolution and reproducibility with this technique." The team hopes that their new technique will open the door for lots of new experiments and discoveries at the... | Through the mechanical interaction between tip and target molecule, or by the electric field in the gap, the STM can induce molecular change across a groundstate potential energy landscape (3) . The STM tunneling current, however, can generate excited states of a molecule and hence give enhanced specificity, and more v... | [2.0, 3.0, 1.0] | Medicine | train | 2 | news | http://ct.moreover.com/?a=37038008290&p=1pl&v=1&x=cdTv0tZ1tttrqFN7rPlSvA |
10.1073/pnas.1318978111 | Medicine_390 | "If these data are confirmed in clinical trials, we could propose that raising low levels of androgens in a woman with diminished ovarian reserve might increase her ability to produce more and better eggs for fertilization." | involve paxillin-mediated synergistic action between nuclear and extranuclear signaling of ARs that induces expression of the antiapoptotic miR-125b and up-regulates expression of the proproliferative FSHR. | "This information is important because it provides theoretical support for administering androgens to some women undergoing IVF, a practice that our fertility clinic and many others across the country have started in recent years," said Hoeger, who is also a professor of Obstetrics and Gynecology at the School of Medic... | In vivo knockdown of miR-125b-2 increases follicular atresia. involve paxillin-mediated synergistic action between nuclear and extranuclear signaling of ARs that induces expression of the antiapoptotic miR-125b and up-regulates expression of the proproliferative FSHR. Our study not only demonstrates miR125b as an impor... | [1.0, 2.0, 1.0, 1.0] | Medicine | train | 1.25 | news | http://www.sciencedaily.com/releases/2014/03/140304141948.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 |
10.1093/chemse/bjt066 | Medicine_391 | When associated with a pleasant label, we enjoy the odour more than when it is presented with a negative label. | Specifically, the effect was also seen for the 2 nonfood odorants suggesting an unbiased effect. | When associated with a pleasant label, we enjoy the odour more than when it is presented with a negative label. The result was that all participants rated the four odours more positively when they were presented with positive labels than when presented with negative labels. Specifically, participants described the odou... | All odorants presented with positive labels were rated as being more edible than when they were presented with negative labels. Specifically, the effect was also seen for the 2 nonfood odorants suggesting an unbiased effect. All odorants presented with positive labels were rated as being more pleasant than when they we... | [4.0, 1.0, 1.0, 2.0] | Medicine | train | 2 | news | http://www.sciencedaily.com/releases/2014/02/140211084007.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 |
10.1098/rsos.180695 | Medicine_392 | We could also be adapting to the cozy indoor climates where we spend most of our time, speculates Gilligan. | Moreover, predictions can be made about the communities of home associates through time and space, as climate, home technologies and fortunes change. | Gilligan said he would be interested to see how people keep their houses in other parts of the world, since there may be differences in preference based on culture and genetics. We could also be adapting to the cozy indoor climates where we spend most of our time, speculates Gilligan. And while the inside of a house ma... | Our results also offer a hypothesis about the likely origin of human home-associated species, as indoor climates probably favour certain lineages, those pre-adapted to indoor climates. Moreover, predictions can be made about the communities of home associates through time and space, as climate, home technologies and fo... | [1.0, 3.0, 4.0, 4.0] | Medicine | train | 2 | news | http://ct.moreover.com/?a=38798635240&p=1pl&v=1&x=dKEYUvmyKXnUNRgeE2st1A |
10.1534/genetics.116.197285 | Medicine_394 | "We expect that resistance alleles will pop up either before the drive can spread, or after the drive spreads, and eventually replace the drive," he said. | Thus, resistance is more likely to evolve from alleles in the SGV than from de novo mutation after introduction of the driver, unless the drive is very slow. | Yet, faced with the new and sophisticated CRISPR/Cas9 method of gene drive, nature is still likely to fight back to resist the mutation successfully, Unckless said. "We expect that resistance alleles will pop up either before the drive can spread, or after the drive spreads, and eventually replace the drive," he said. ... | We find that in most scenarios P SGV is higher than P μ . Thus, resistance is more likely to evolve from alleles in the SGV than from de novo mutation after introduction of the driver, unless the drive is very slow. The key parameter determining the likelihood of resistance from NHEJ is the product N e δ, similar to th... | [3.0, 2.0, 4.0, 3.0, 4.0] | Medicine | train | 3.2 | news | http://healthmedicinet.com/news/research-shows-nature-can-beat-back-scientific-tinkering-with-genes-of-entire-species/ |
10.1002/hec.3070 | Medicine_395 | A 20 per cent sales tax would raise annual costs per person by about $15 to $17. | show that a 20% increase in price will lead to reductions in consumption of 17.67%, 46.5% and 20.03% of regular soft drinks, cordial and fruit juice respectively. | Although both taxes would be regressive, representing a greater proportion of lower incomes than higher ones, the proposed rates would keep this effect mild, Dr Sharma said. A 20 per cent sales tax would raise annual costs per person by about $15 to $17. But in weight-loss terms, average consumption would drop by more ... | These effects are expressed in percentage changes in quantities of all ten non-alcoholic beverages once the 20% tax is applied on regular soft drinks, cordial and fruit drinks. show that a 20% increase in price will lead to reductions in consumption of 17.67%, 46.5% and 20.03% of regular soft drinks, cordial and fruit ... | [3.0, 1.0, 2.0, 2.0] | Medicine | train | 2 | news | http://www.sciencedaily.com/releases/2014/06/140617094037.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 |
10.1073/pnas.1403984111 | Medicine_396 | The data also show that the destination of the illegally trafficked ivory increasingly shifted to China. | At the intensively monitored site, illegal killing increased markedly after 2008 and was correlated strongly with the local black market ivory price and increased seizures of ivory destined for China. | This surge was directly correlated to a more than quadrupling of local black-market ivory prices paid to poachers and tripling in the volume and number of illegal ivory seizures through Kenyan ports of transit. The data also show that the destination of the illegally trafficked ivory increasingly shifted to China. Such... | At the intensively monitored site, illegal killing increased markedly after 2008 and was correlated strongly with the local black market ivory price and increased seizures of ivory destined for China. More broadly, results from application to continental data indicated illegal killing levels were unsustainable for the ... | [4.0, 4.0, 4.0, 3.0, 3.0] | Medicine | train | 3.6 | news | http://www.newswise.com/articles/colorado-state-university-study-verifies-more-than-100-000-african-elephants-killed-in-three-years |
10.1073/pnas.1424293112 | Medicine_397 | The discovery of their existence, outlined this week in a study in The Proceedings of the National Academy of Sciences, brings researchers one-step closer to fully understanding how the fungus attacks and kills trees. | Most of the M. populorum secondary metabolite cluster proteins were found nested within a group of Eurotiomycetes fungi, including P. oxalicum, as expected under the hypothesis that the cluster was transferred from a Eurotiomycetes ancestor through a horizontal transfer event ( Fig. | The discovery of their existence, outlined this week in a study in The Proceedings of the National Academy of Sciences, brings researchers one-step closer to fully understanding how the fungus attacks and kills trees. "Our findings will help us develop better methods to detect the fungus and prevent its spread," says s... | The striking conservation in synteny and gene sequence as well as the sporadic distribution of the full cluster in only two groups of the fungal phylogeny (Dothideomycetes and Eurotiales) raises the possibility that this cluster was acquired through horizontal gene transfer (HGT) (Fig. Most of the M. populorum secondar... | [1.0, 3.0, 2.0, 2.0] | Medicine | train | 2 | news | http://www.sciencedaily.com/releases/2015/03/150304104352.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29 |
10.1186/2045-5380-3-19 | Medicine_398 | But, the stabilizing effects of CBD can help patients through withdrawal. | As hippocampal volume is known to be reduced in major depression , and reduced hippocampal volume is thought to be a risk factor in PTSD , these data would suggest that polymorphisms in the CNR1 gene that result in greater CB1 receptor activity may result in increased hippocampal volume and thus provide a neural substr... | That said, due to the withdrawal symptoms of Adderall, those with ADHD should consult their doctor before changing their treatment. But, the stabilizing effects of CBD can help patients through withdrawal. And, CBD also offers continuing support as an effective alternative to Adderall in the long-term. | Taken together, these studies would suggest that the A allele in the rs1049353 polymorphism of the CNR1 gene results in some level of protection against the development of depression, particularly in response to stress exposure. As hippocampal volume is known to be reduced in major depression , and reduced hippocampal ... | [1.0, 1.0, 1.0, 1.0] | Medicine | train | 1 | news | http://ct.moreover.com/?a=38859700967&p=1pl&v=1&x=UP_btp_fYMUlHDGz6aK1Xw |
10.1007/s13524-014-0321-x | Medicine_399 | The happiness level of parents varied among different ages. | We assume the cardinality of life satisfaction because treating life satisfaction as ordinal versus cardinal makes little difference . | On the third child, parents inadvertently switched back to their "pre-child happiness level," according to LSE. The happiness level of parents varied among different ages. Those aged 35 to 49 experienced the highest level of happiness, while those between age 18 and 22 reported a decline in their happiness. | We experimented with both measures, and like , we found that our results were very similar independent of the measure, the key difference being the loss in statistical power for the sporadically measured life satisfaction. We assume the cardinality of life satisfaction because treating life satisfaction as ordinal vers... | [1.0, 2.0, 1.0, 1.0] | Medicine | train | 1.25 | news | http://www.hngn.com/articles/47780/20141031/births-of-first-and-second-child-bring-parents-more-happiness-than-the-third-but-why.htm |
10.1001/jama.2018.20578 | Medicine_4 | >>
Le Dr. Zheng a explique que l'usage de l'aspirine devrait donner lieu a une discussion entre les patients et les medecins, et leur preciser que toute amelioration de leur sante cardiovasculaire, meme minime, implique << un reel risque d'hemorragie grave >>. | In this meta-analysis, the use of aspirin in individuals without cardiovascular disease was associated with a lower risk of cardiovascular events and an increased risk of major bleeding. | Cette etude montre que, si les incidents cardiovasculaires peuvent etre reduits chez ces patients, les avantages sont confrontes a un plus grand risque d'incidents hemorragiques majeurs. >>
Le Dr. Zheng a explique que l'usage de l'aspirine devrait donner lieu a une discussion entre les patients et les medecins, et leu... | 19, 22 Increasing adoption of additional primary prevention strategies, such as risk factor modification and development of public health initiatives, may limit the applicability of earlier studies to current practice. In this meta-analysis, the use of aspirin in individuals without cardiovascular disease was associate... | [1.0, 1.0, 4.0, 5.0, 3.0] | Medicine | train | 4 | news | http://ct.moreover.com/?a=38330869620&p=1pl&v=1&x=M8k770LVWvQytywr57cyKg |
10.1016/j.childyouth.2014.05.001 | Medicine_400 | Low levels of self-esteem and poor emotional processing skills were significantly correlated with gang involvement, as were low levels of parental monitoring, poor parental communication and housing instability. | Major findings also indicated that low levels of parental monitoring, poor parental communication and housing instability were significantly associated with gang involvement. | Among the 188 participants, 66 percent reported having received food stamps, 58 percent reported housing instability (either being thrown out of their house or running away from home), 52 percent reported living in neighborhoods with poor quality (living on a street with abandoned homes or apartments; buildings with br... | Similarly, our findings support earlier studies documenting that emotional processing ability has been associated with the quality of social interactions with both friends and family , and antisocial behavior and delinquency over time ). Major findings also indicated that low levels of parental monitoring, poor parenta... | [2.0, 4.0, 5.0, 5.0] | Medicine | train | 5 | news | http://www.sciencedaily.com/releases/2014/08/140827151656.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 |
10.1007/s10484-015-9286-9 | Medicine_402 | "Because evidence shows that low HRV is a potential risk factor for sexual dysfunction, physicians have a simple, low-cost and nonintrusive method to measure a woman's risk for sexual dysfunction," said Stanton. | In conclusion, low HRV may be a risk factor for female sexual arousal dysfunction and overall sexual dysfunction. | With recent support from the Food and Drug Administration on what could be the first-ever approved drug for the treatment of female sexual dysfunction, the researchers believe that HRV could be used as an index of drug-related changes in sexual function. "Because evidence shows that low HRV is a potential risk factor f... | Women with below average HRV were significantly more likely to report sexual arousal dysfunction (p \ .001) and overall sexual dysfunction (p \ .001) than both women with average HRV and women with above average HRV. In conclusion, low HRV may be a risk factor for female sexual arousal dysfunction and overall sexual dy... | [4.0, 5.0, 4.0, 4.0, 4.0] | Medicine | train | 4.2 | news | http://www.newswise.com/articles/study-links-heartbeat-to-female-libido |
10.1007/s10803-013-1920-x | Medicine_403 | No child had both SCQ and ADOS scores in the relevant ranges that would lead to an ASD diagnosis. | In this study, not one child met strict diagnostic criteria for ASD using results of both the ADOS and SCQ. | Only two -- 7 percent -- had SCQ scores above the cut off. No child had both SCQ and ADOS scores in the relevant ranges that would lead to an ASD diagnosis. It's quite clear that children with the disorder do have social impairments," Simon said. | While it is important to note that research evaluations are not substitutes for clinical evaluations, it is useful to examine the yield of ASD diagnoses based on criteria that more closely resemble what is used in clinical practice (both directly administered assessment and parental history). In this study, not one chi... | [5.0, 5.0, 5.0, 5.0] | Medicine | train | 5 | news | http://www.sciencedaily.com/releases/2013/09/130918090845.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29 |
10.1186/s13058-018-1049-0 | Medicine_404 | Using this research, physicians could monitor their patients with bone marrow aspirates. | This opens the way for testing new treatments that prevent metastasis by inducing/enforcing dormancy, and/or to eradicate MRD . | The research is especially important in the United States because bone marrow tests, called aspirates, are not used to monitor patients there. Using this research, physicians could monitor their patients with bone marrow aspirates. Tests for the protein could also help clinicians identify patients who may benefit from ... | Improved techniques to assess the MRD population and their dormant or reactivating state will be key to identifying the risk of future metastasis despite undergoing standard treatment. This opens the way for testing new treatments that prevent metastasis by inducing/enforcing dormancy, and/or to eradicate MRD . These d... | [1.0, 2.0, 2.0, 4.0, 1.0] | Medicine | train | 2 | news | http://ct.moreover.com/?a=37400845010&p=1pl&v=1&x=9kQQeeV3wfEGbY0w3Hhy5Q |
10.1111/psyp.12228 | Medicine_408 | By 35 weeks, the fetus responds to familiar music with a change in movement patterns. | Note, however, that this may not be a mechanism of prenatal cultural transfer specific to music, but that physiological responses in Enhanced response to music in pregnancypregnant women may be enhanced to acoustic stimulation in general, a question that is not addressed in the current study. | However, non-pregnant women were taking birth control contraceptives, which influences estrogen levels greatly and they did not register the same strong emotions that pregnant women had felt toward each type of music. By 35 weeks, the fetus responds to familiar music with a change in movement patterns. Enhanced Respons... | Our finding suggests that the physiological response of the mother is enhanced with respect to a specific type of acoustical stimulus, namely, music, which may in turn partly underlie the strong physiological effects of music on the listener. Note, however, that this may not be a mechanism of prenatal cultural transfer... | [3.0, 5.0, 2.0, 3.0, 2.0] | Medicine | train | 3 | news | http://www.medicaldaily.com/pregnant-women-have-stronger-response-music-enough-raise-their-blood-pressure-284496 |
10.1001/jama.2018.20578 | Medicine_41 | They found that while it was associated with a lower risk of heart attacks and other cardiovascular events, it did lead to an increased risk of major bleeding. | Aspirin use was associated with significant reductions in the composite cardiovascular outcome compared with no aspirin (57.1 per 10 000 participant-years with aspirin and 61.4 per 10 000 participant-years with no aspirin) (hazard ratio CONCLUSIONS AND RELEVANCE The use of aspirin in individuals without cardiovascular ... | They found that while it was associated with a lower risk of heart attacks and other cardiovascular events, it did lead to an increased risk of major bleeding. The results showed that:
Aspirin use was associated with an 11% lower risk of cardiovascular events. Approximately 250 patients needed to be treated with aspir... | The median age of trial participants was 62 years (range, 53-74), 77 501 (47%) were men, 30 361 (19%) had diabetes, and the median baseline risk of the primary cardiovascular outcome was 9.2% (range, 2.6%-15.9%). Aspirin use was associated with significant reductions in the composite cardiovascular outcome compared wit... | [5.0, 5.0, 3.0] | Medicine | train | 4.333333 | news | https://www.sciencedaily.com/releases/2019/01/190122114950.htm |
10.1038/s41598-018-25671-7 | Medicine_411 | The researchers acknowledge that YouTube videos of dog bites are likely subject to some bias, with, for example, bites by small dogs perhaps perceived as "comical" and therefore more likely to be uploaded online. | We also did not include a breed as a predictor variable due to documented problems in recognising a breed based on visual characteristics 30 and a small number of dogs in each breed category. | For 56 of these videos they were also able to analyse the details of human and dog behaviour leading up to the bite. The researchers acknowledge that YouTube videos of dog bites are likely subject to some bias, with, for example, bites by small dogs perhaps perceived as "comical" and therefore more likely to be uploade... | Moreover, not all variables which are often cited in literature as risk factors for bites were used as predictor variables in our model as it was not always possible to discern them from the video. We also did not include a breed as a predictor variable due to documented problems in recognising a breed based on visual ... | [3.0, 3.0, 2.0, 2.0] | Medicine | train | 2.5 | news | http://ct.moreover.com/?a=34019053777&p=1pl&v=1&x=5nYw5SbVJSqoLC3Qtatd9A |
10.1001/jamaoncol.2018.2254 | Medicine_413 | The researchers identified 1,063 deaths during a median follow-up of 9.6 years. | There was a significant inverse association across quartiles of exercise and all-cause mortality after adjusting for chronic health conditions and treatment exposures (P = .02 for trend). | The researchers identified 1,063 deaths during a median follow-up of 9.6 years. At 15 years, the cumulative incidence of all-cause mortality was 11.7, 8.6, 7.4, and 8 percent for those who exercised zero, three to six, nine to 12, and 15 to 21 MET-hours/week, respectively. After adjustment for chronic health conditions... | At 15 years, the cumulative incidence of all-cause mortality was 11.7% (95% CI, 10.6%-12.8%) for those who exercised 0 MET-h/wk, 8.6% (95% CI, 7.4%-9.7%) for 3 to 6 MET-h/wk, 7.4% (95% CI, 6.2%-8.6%) for 9 to 12 MET-h/wk, and 8.0% (95% CI, 6.5%-9.5%) for 15 to 21 MET-h/wk (P < .001). There was a significant inverse ass... | [3.0, 2.0, 2.0, 1.0, 1.0] | Medicine | train | 1.8 | news | http://ct.moreover.com/?a=34289670602&p=1pl&v=1&x=a-vHk9gR3QeZmhOGRMfTUQ |
10.1080/08870446.2014.918267 | Medicine_414 | Interestingly, in the second experiment, overweight viewers of food ads reported a stronger desire to eat than those in the control group. | The overweight and obese sample here reported a stronger desire to eat following priming with a series of television advertisements for food products than when primed with advertisements for non-food products. | Researchers found that in both experiments, those shown food ads produced more food related words, suggesting that the advertising does activate increased food-related cognitions. Interestingly, in the second experiment, overweight viewers of food ads reported a stronger desire to eat than those in the control group. E... | In contrast to Experiment 1, exposure to television food advertising also affected ratings of desire to eat. The overweight and obese sample here reported a stronger desire to eat following priming with a series of television advertisements for food products than when primed with advertisements for non-food products. T... | [4.0, 2.0, 3.0, 4.0] | Medicine | train | 3.25 | news | http://www.hngn.com/articles/40594/20140828/food-advertisements-make-eat-more-study-confirms.htm |
10.1073/pnas.1418572112 | Medicine_415 | Children who had acquired a hostile attributional bias were more likely than other children to grow in the rate and severity of their aggressive behavior across the four years of the study. | As expected, motherrated and child-rated chronic aggressive behavior problem scores were significantly correlated with each other and with similar scores across years. | In fact, on average, they were five times more likely to do so than children who accepted the act as non-hostile. Children who had acquired a hostile attributional bias were more likely than other children to grow in the rate and severity of their aggressive behavior across the four years of the study. Expanded Golden ... | Likewise, internal consistency of individual differences in selfpredicted reactive aggression was high overall (ρ = 0.95; 95% CI: 0.94, 0.96) and in each group. As expected, motherrated and child-rated chronic aggressive behavior problem scores were significantly correlated with each other and with similar scores acros... | [3.0, 3.0, 3.0, 4.0] | Medicine | train | 3.25 | news | http://www.futurity.org/children-hostility-violence-960852/ |
10.1073/pnas.1614389114 | Medicine_417 | "Pride appears to be an elegantly engineered emotion: It makes you pursue socially valued courses of action, and it facilitates the gains in esteem that make those actions worth pursuing." | This suggests that pride, rather than other positive emotions, is distinctively involved in social valuation. | This may explain why pride is a target of righteous indignation around the world. "A careful mapping of this emotion suggests a different view, however," he continues. "Pride appears to be an elegantly engineered emotion: It makes you pursue socially valued courses of action, and it facilitates the gains in esteem that... | Further, pride is specific to audience valuation: Emotions that co-activate with pride, such as happiness and excitement, do not track audience valuation uniquely and reliably. This suggests that pride, rather than other positive emotions, is distinctively involved in social valuation. Further evidence to demonstrate d... | [4.0, 5.0, 4.0, 5.0, 5.0] | Medicine | train | 4.6 | news | http://www.futurity.org/pride-evolution-emotions-1357352-2/ |
10.1098/rsos.172398 | Medicine_418 | A new study on dog behavior may help us better understand how human personalities affect obesity. | These results are very similar to those expected from the parallel models that exist between certain personality traits and being overweight in humans, suggesting that dogs are indeed a promising model for experimentally investigating obesity in humans. | A new study on dog behavior may help us better understand how human personalities affect obesity. The scientists thought that the obese dogs would be more likely to wait for the potential high-value meal, that they would do anything for something big and tasty. However, that was not the case. | Our results also confirm that overweight dogs, as opposed to normal weight dogs, tried to maximize food intake from the higher quality food and hesitated to do the task when the food reward was uncertain. These results are very similar to those expected from the parallel models that exist between certain personality tr... | [3.0, 5.0, 4.0, 4.0] | Medicine | train | 4 | news | http://ct.moreover.com/?a=34325969822&p=1pl&v=1&x=salba5rYf-HICBtD5mnRpg |
10.1016/j.biopsych.2013.07.024 | Medicine_419 | Associations between prenatal exposure to both glucocorticoids -- particularly cortisol -- and tobacco smoke emerged only for daughters, which Stroud says it consistent with some recent research findings. | Given evidence for more pronounced MSDP-offspring smoking links in daughters (12-14, 16,17,19,24) and for sex differences in prenatal glucocorticoid levels (59) and offspring outcomes after prenatal glucocorticoid exposure (60), we also hypothesized that links between prenatal glucocorticoids and offspring ND would be ... | Because mothers who smoke are often more stressed and living in adverse conditions -- these findings represent a public health concern and highlight the need to help smoking moms quit and reduce stress levels and improve social conditions for poor pregnant mothers," Stroud added. Associations between prenatal exposure ... | Thus, we propose that maternal cortisol levels might mediate the relation between MSDP and offspring ND. Given evidence for more pronounced MSDP-offspring smoking links in daughters (12-14, 16,17,19,24) and for sex differences in prenatal glucocorticoid levels (59) and offspring outcomes after prenatal glucocorticoid e... | [4.0, 3.0, 5.0, 4.0] | Medicine | train | 4 | news | http://psychcentral.com/news/2013/10/08/risk-for-nicotine-addiction-tied-to-mothers-childbirth-stress/60475.html |
10.1038/s41593-018-0289-8 | Medicine_421 | "Our current study reinforces growing evidence suggesting that A-beta and tau work together to impair brain function and that, for certain aspects of that impairment, tau predominates. | Again, ELISA analysis showed a substantial reduction in total human tau levels in all mice receiving DOX ( Supplementary Fig. | The findings suggest that strategies directed against both pathologic proteins, rather than one or the other, might be promising therapeutic options. "Our current study reinforces growing evidence suggesting that A-beta and tau work together to impair brain function and that, for certain aspects of that impairment, tau... | ), demonstrating that the difference between the effects of DOX treatment in the young rTg4510 and APP/PS1-rTg4510 mice were highly significant. Again, ELISA analysis showed a substantial reduction in total human tau levels in all mice receiving DOX ( Supplementary Fig. As a control, we treated wild-type control mice w... | [2.0, 2.0, 1.0, 3.0] | Medicine | train | 2 | news | http://ct.moreover.com/?a=38148348820&p=1pl&v=1&x=3selMPRuYABgNhN6T6VMqw |
10.1111/infa.12017 | Medicine_422 | "This is the first study to show a matching ability with an infant this young. | The present findings are the first to show 5-month-olds match the faces and voices of other infants on the basis of global invariant properties common to facial and vocal emotional expressions. | "We found that 5 month old infants can match their peer's positive and negative vocalizations with the appropriate facial expression," says Flom. "This is the first study to show a matching ability with an infant this young. They are exposed to affect in a peer's voice and face which is likely more familiar to them bec... | These temporal and intensity patterns are invariant across face and voice and may specify different emotional valences which can be detected only in dynamic, moving expressions ) where changes in intensity and temporal patterns are evident. The present findings are the first to show 5-month-olds match the faces and voi... | [5.0, 5.0, 5.0, 3.0, 3.0] | Medicine | train | 4.2 | news | http://www.healthcanal.com/mental-health-behavior/40222-babies-can-read-each-other%E2%80%99s-moods%2C-study-finds.html |
10.1126/sciadv.1400121 | Medicine_423 | These immune signatures represent the first robust physical evidence that ME/CFS is a biological illness as opposed to a psychological disorder, and the first evidence that the disease has distinct stages. | Integration of these immune markers with clinical findings will provide clinicians with a stronger framework for establishing an ME/CFS diagnosis, and, possibly, make it easier to rule out other conditions at an earlier time point. | The findings could help improve diagnosis and identify treatment options for the disabling disorder, in which symptoms range from extreme fatigue and difficulty concentrating to headaches and muscle pain. These immune signatures represent the first robust physical evidence that ME/CFS is a biological illness as opposed... | First, we were able to define a distinctive immune signature that differed from that of healthy controls. Integration of these immune markers with clinical findings will provide clinicians with a stronger framework for establishing an ME/CFS diagnosis, and, possibly, make it easier to rule out other conditions at an ea... | [2.0, 3.0, 3.0, 4.0] | Medicine | train | 3 | news | http://www.sciencedaily.com/releases/2015/02/150227144903.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29 |
10.1001/jamainternmed.2013.6536 | Medicine_425 | advertisement
The authors uncovered a striking benefit: Men who replaced 10 percent of their total daily calories from carbohydrates with healthy vegetable fats had a 29 percent lower risk of developing lethal prostate cancer and a 26 percent lower risk of dying from all causes. | In this prospective analysis, vegetable fat intake after diagnosis was associated with a lower risk of lethal prostate cancer and all-cause mortality. | During the study timeframe, 1,064 men died, primarily from cardiovascular disease (31 percent), prostate cancer (21 percent) and other cancers (nearly 21 percent). advertisement
The authors uncovered a striking benefit: Men who replaced 10 percent of their total daily calories from carbohydrates with healthy vegetable... | Post-diagnostic intakes of mayonnaise and margarine were not associated with risk of lethal prostate cancer or all-cause mortality. In this prospective analysis, vegetable fat intake after diagnosis was associated with a lower risk of lethal prostate cancer and all-cause mortality. Among 525 Swedish men, marine fatty a... | [4.0, 3.0, 4.0, 3.0] | Medicine | train | 3.5 | news | http://www.sciencedaily.com/releases/2013/06/130610192948.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29 |
10.1038/s41467-019-10570-w | Medicine_427 | It has to link to Ran first in order to reach the cell membrane. | In fact, the Ran association with RhoA prevents its ubiquitin-mediated proteasomal degradation through promoting RhoA localization to the PM and then its activation. | "In normal cells, RhoA can make its way directly to the cell membrane but in ovarian cancer cells it cannot. It has to link to Ran first in order to reach the cell membrane. "In our study, we showed that in cancer cells where we inhibit the action of Ran, RhoA gets broken down. | In summary, this study provides an undescribed link between Ran and RhoA signaling that collectively contributes to enhanced ovarian cancer cell growth and invasiveness. In fact, the Ran association with RhoA prevents its ubiquitin-mediated proteasomal degradation through promoting RhoA localization to the PM and then ... | [2.0, 2.0, 4.0, 2.0, 1.0] | Medicine | train | 2.2 | news | http://ct.moreover.com/?a=39652157590&p=1pl&v=1&x=iLAV7nt5Bd4yspqFvXSuQg |
10.1038/s41467-018-05870-6 | Medicine_43 | "This allows us to explore the potential of finding a novel therapeutic approach that alters energy balance in obesity and modulates the associated diseases." | The regulation of energy metabolism by Ago2 provides a novel paradigm in which RNA silencing plays an integral role in determining basal metabolic activity in obesity-associated sequelae. | "Although this is still basic science, we propose that there may be important translational implications for our findings for chronic metabolic disorders like diabetes, fatty liver diseases, and other obesity associated illnesses," said Nakamura, senior investigator and a member of the Division of Endocrinology. "This ... | Notably, hepatic Ago2-deficiency improves glucose metabolism in conditions of insulin receptor antagonist treatment, high-fat diet challenge, and hepatic AMPKα1-deletion. The regulation of energy metabolism by Ago2 provides a novel paradigm in which RNA silencing plays an integral role in determining basal metabolic ac... | [4.0, 4.0, 3.0, 4.0] | Medicine | train | 3.75 | news | http://ct.moreover.com/?a=37061323146&p=1pl&v=1&x=l5-40ws2AOkos3TN_hE55A |
10.1542/peds.2014-2707 | Medicine_430 | While the reasons for the difference in sleep times is unclear, it could be due to housing quality, obesity, and conditions that disrupt sleep, as well as worrying about money, of course. | Cohort effects were also observed for some subgroups, particularly in $7 hours of sleep for male subjects, white subjects, and those in urban areas; those in the earliest cohorts, as well as cohorts born in the early 1990s, were more likely to report regular $7 hours of sleep compared with all other adolescents. | Despite the fact that the recommended amount of sleep for adolescents is nine hours, students from lower-income families and ethnic minorities did not report having more than seven hours of sleep a night. While the reasons for the difference in sleep times is unclear, it could be due to housing quality, obesity, and co... | Thus, these data indicate that adolescent sleep is declining across all age groups and major sociodemographic subgroups. Cohort effects were also observed for some subgroups, particularly in $7 hours of sleep for male subjects, white subjects, and those in urban areas; those in the earliest cohorts, as well as cohorts ... | [5.0, 3.0, 2.0, 4.0, 5.0] | Medicine | train | 3.8 | news | http://www.inquisitr.com/1865139/rich-americans-sleep-better-at-night-than-poor-ones-study-finds/ |
10.1001/jamaoto.2018.1446 | Medicine_431 | >> RELATED: Hi-tech nose helps sniff out cancer, 16 other diseases by analyzing breath
After analyzing the results, they discovered that the ability to identify odors decreases with age, while phantom odor perception seems to improve with age. | In this cross-sectional study of 7417 adults, the prevalence of phantom odor perception was 6.5% (n = 534) and was greater among women, younger age groups, and those of lower socioeconomic position. | >> RELATED: Hi-tech nose helps sniff out cancer, 16 other diseases by analyzing breath
After analyzing the results, they discovered that the ability to identify odors decreases with age, while phantom odor perception seems to improve with age. Furthermore, they said that one in 15 Americans experience phantom odors. I... | Overall response rates for the interviewed sample were 72.6% in the 2011-2012 period and 71.0% in the 2013-2014 period. In this cross-sectional study of 7417 adults, the prevalence of phantom odor perception was 6.5% (n = 534) and was greater among women, younger age groups, and those of lower socioeconomic position. P... | [3.0, 4.0, 2.0, 4.0] | Medicine | train | 3.25 | news | http://ct.moreover.com/?a=34841635020&p=1pl&v=1&x=HkVZeOeHcFcX4nK0eYTeTw |
10.1038/srep03141 | Medicine_432 | "Increases in Flickr photo counts with particular labels may reveal notable increases in attention to a particular issue, which in some cases may merit further investigation for policymakers." | We find a striking correlation between the moving average of the normalized number of Hurricane Sandy related Flickr photos taken and the atmospheric pressure in New Jersey for Dt 5 24 hours (Kendall's tau 5 20.37, z 5 215.14, p , 0.001). | This probably doesn't come as a surprise to anyone familiar with social media. "Increases in Flickr photo counts with particular labels may reveal notable increases in attention to a particular issue, which in some cases may merit further investigation for policymakers." Through their analysis, scientists from the Warw... | Visualization of the data reveals that the normalized number of photos taken increased continuously while ''Sandy'' was moving toward the coast of the United States ( Figure 1A ). We find a striking correlation between the moving average of the normalized number of Hurricane Sandy related Flickr photos taken and the at... | [4.0, 2.0, 4.0, 4.0] | Medicine | train | 3.5 | news | http://www.ibtimes.com/can-flickr-predict-natural-disasters-hurricane-sandy-created-digital-trace-when-photo-uploads-peaked |
10.1016/j.jpsychires.2013.06.014 | Medicine_433 | Dr Bilderbeck added: 'This was only a preliminary study, but nothing has been done like this before. | Participation in the yoga course significantly influenced positive affect as measured by the PANAS, F(1,86) ¼ 5.26, p ¼ 0.024. | 'The suggestion is that yoga is helpful for these prisoners.' Dr Bilderbeck added: 'This was only a preliminary study, but nothing has been done like this before. Offering yoga sessions in prisons is cheap - much cheaper than other mental health interventions. | The average time that participants in the yoga group spent practising yoga (outside of class) did not differ significantly when compared to the time spent by the control group doing other forms of exercise (167.1 AE 48.4 min vs. 241.76 AE 27.0 min, respectively), t(75) ¼ À1.46, p ¼ 0.15. Participation in the yoga cours... | [1.0, 1.0, 1.0, 3.0, 1.0] | Medicine | train | 1.4 | news | http://www.healthcanal.com/alternative-therapies/40699-prisoners-doing-yoga-may-see-psychological-benefits.html |
10.1111/acer.12656 | Medicine_434 | "We found that lower results on IQ tests in Swedish adolescent men are associated with a higher consumption of alcohol, measured in both terms of total intake and binge drinking," said Sjolund. | They found a J-shaped association between frequency of drinking and IQ test results, where the daily drinkers had the lowest IQ. | "It could be the other way around for a minority of individuals, that is, when exposure to alcohol has led to cognitive impairment, but this is less likely to be found among young persons of course." "We found that lower results on IQ tests in Swedish adolescent men are associated with a higher consumption of alcohol, ... | It should be noted that the authors report a skewed study population with regard to low socioeconomic position . They found a J-shaped association between frequency of drinking and IQ test results, where the daily drinkers had the lowest IQ. A higher IQ was associated with being a rare, an occasional, and a moderate dr... | [4.0, 4.0, 4.0, 5.0] | Medicine | train | 4.25 | news | http://www.sciencedaily.com/releases/2015/02/150220190744.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29 |
10.1016/j.cels.2017.12.013 | Medicine_435 | As people pack on pounds or shed excess weight, they exhibit notable changes in their microbiome, cardiovascular system, immune system and levels of gene expression, the study found. | Extensive multi-omic profiling of the blood and microbiomes of healthy and insulin-resistant humans as they gain and lose weight reveals insights into the systemic impacts of weight gain. | / no comments
Medicine, Health Care Weight Flux Alters Molecular Profile,... As people pack on pounds or shed excess weight, they exhibit notable changes in their microbiome, cardiovascular system, immune system and levels of gene expression, the study found. "Omics" is equivalent to tacking on "the study of" to the n... | Graphical Abstract Highlights d Analysis of insulin-sensitive and -resistant individuals across multiple omes d We reveal molecular changes in the human body after modest short-term weight gain d Reversal of short-term weight gain eliminates negative molecular alterations d Open-access multi-omic resource for further b... | [2.0, 4.0, 5.0, 4.0, 4.0] | Medicine | train | 3.8 | news | http://healthmedicinet.com/news/weight-flux-alters-molecular-profile-stanford-led-study-finds/ |
10.1001/jamapsychiatry.2013.2163 | Medicine_436 | The risks associated with maternal depression during pregnancy and maternal depression after pregnancy are clearly different. | Analyses found that maternal education moderated the effects of postnatal but not antenatal depression. | In particular, the findings suggest that treating depression in pregnancy, irrespective of background, may be most effective." The risks associated with maternal depression during pregnancy and maternal depression after pregnancy are clearly different. While maternal education can decrease the risks from postpartum dep... | However, for more educated mothers, there was little association (odds ratio, 1.09; 95% CI, 0.88-1.36; P = .42). Analyses found that maternal education moderated the effects of postnatal but not antenatal depression. Paternal depression antenatally was not associated with offspring depression, while postnatally, patern... | [4.0, 2.0, 4.0, 2.0] | Medicine | train | 3 | news | http://www.inquisitr.com/987314/maternal-depression-during-pregnancy-linked-to-depression-in-young-adults/ |
10.1073/pnas.1605782113 | Medicine_438 | Sound-meaning association biases evidenced across thousands of languages. | Hence, the explanation for the observed prevalence of sound-meaning associations across the world has to be found elsewhere (49). | "Likely it has something to do with the human mind or brain, our ways of interacting, or signals we use when we learn or process language. That's a key question for future research." Sound-meaning association biases evidenced across thousands of languages. | These results suggest that, although it is possible that the presence of signals in some families are symptomatic of a particularly pervasive cognate set, this is not the usual case. Hence, the explanation for the observed prevalence of sound-meaning associations across the world has to be found elsewhere (49). We have... | [5.0, 4.0, 3.0, 4.0, 4.0] | Medicine | train | 4 | news | http://feedproxy.google.com/~r/BreakingScienceNews/~3/UITWK-W4wO8/languages-use-same-sounds-common-objects-ideas-04185.html |
10.1002/ece3.3060 | Medicine_44 | Distance between ponds and various landscape features could not fully explain the observed genetic differences. | found that no landscape surface described genetic differentiation demonstrably better than distance alone and our work expanding the number of ponds landscape surface described genetic differentiation demonstrably better than distance alone. | DNA analysis showed that salamanders that breed in the fall move to new ponds less often than salamanders that breed in the spring. Distance between ponds and various landscape features could not fully explain the observed genetic differences. "Even though some habitat features seemed to affect dispersal, we found that... | The support for a composite surface of TPI and distance from ravines explaining the genetic differentiation for A. annulatum and eastness describing genetic differentiation for A. maculatum extends previous work with A. annulatum and A. maculatum on this landscape. found that no landscape surface described genetic diff... | [2.0, 3.0, 4.0, 5.0] | Medicine | train | 3.5 | news | http://www.futurity.org/salamanders-breeding-1515412-2/ |
10.1038/s41588-018-0175-z | Medicine_440 | The video demonstrates that physical contact between the enhancer and the gene is necessary to activate transcription, the first step in reading the genetic instructions. | We show that sustained proximity of the enhancer to its target is required for activation. | The video demonstrates that physical contact between the enhancer and the gene is necessary to activate transcription, the first step in reading the genetic instructions. The researchers also found that during transcription, the structure formed by the enhancer and gene becomes more compact, suggesting a change in the ... | Even for a compact genome such as Drosophila melanogaster, at least 30% of enhancer-promoter interactions occur over 20 kb, and in many cases over intervening genes . We show that sustained proximity of the enhancer to its target is required for activation. Transcription in turn affects the three-dimensional topology a... | [1.0, 5.0, 5.0, 5.0, 5.0] | Medicine | train | 5 | news | http://ct.moreover.com/?a=34614782738&p=1pl&v=1&x=jOJzAOciM3ZzT6ZVS5rOkg |
10.1038/ncomms16015 | Medicine_441 | Professor Nick Wareham, director of the MRC Epidemiology Unit and a senior author of the study, noted: "This work highlights the importance of muscle strength in the prevention of fractures and the complications which can often follow a fall." | We also performed Mendelian randomization (MR) analyses, which showed no evidence for causality in the associations of grip strength with CVD or all-cause mortality, but were suggestive of a causal effect of muscular strength on fracture risk. | Using the sixteen genetic variants identified for strength, the researchers were able to investigate the hypothesised causal link between strength and these adverse health outcomes. Their study found no evidence that lower strength causally increases risk of death or cardiovascular disease, but they did find evidence t... | Grip strength is highly heritable (h 2 ¼ 30-65%) [10] . We also performed Mendelian randomization (MR) analyses, which showed no evidence for causality in the associations of grip strength with CVD or all-cause mortality, but were suggestive of a causal effect of muscular strength on fracture risk. Multiple novel loci ... | [2.0, 2.0, 4.0, 5.0, 3.0] | Medicine | train | 3.2 | news | http://feedproxy.google.com/~r/TechnologyOrg/~3/QIOvIvcpAuc/ |
10.1073/pnas.1812786116 | Medicine_442 | "While we found moderate effects at the national level, these results reflect mean differences," Karbownik said. | We do not have direct measures of prenatal testosterone exposure in our administrative data (e.g., from amniotic fluid), and models using all twin births cannot differentiate in utero testosterone exposure from the postbirth socialization effects of being raised with a male co-twin. | "But whether we view those effects as 'positive' or 'negative' may be culturally dependent." "While we found moderate effects at the national level, these results reflect mean differences," Karbownik said. "Not everyone will be affected in the same way, and some female twins may not be affected at all. | Consistent with some past studies, there was minimal evidence of any long-term impacts on males of exposure to a female co-twin (SI Appendix, Table S2 ). We do not have direct measures of prenatal testosterone exposure in our administrative data (e.g., from amniotic fluid), and models using all twin births cannot diffe... | [1.0, 1.0, 1.0, 2.0, 2.0] | Medicine | train | 1.4 | news | http://ct.moreover.com/?a=38791064033&p=1pl&v=1&x=s_hKDbNKNwMBE8lWCXruqQ |
10.3945/ajcn.113.066688 | Medicine_443 | Now, findings from Monell reveal that a person's sensitivity to bitter taste is shaped not only by which taste genes that person has, but also by how much messenger RNA -- the gene's instruction guide that tells a taste cell to build a specific receptor - their cells make. | We provide the first experimental evidence that mRNA expression amounts of the PAV allele of the TAS2R38 taste receptor gene correlate with sensory perception of bitterness and with dietary habits in humans. | However, some perplexing pieces of the puzzle remained, as two people with exactly the same genetic makeup can still differ markedly regarding how bitter certain foods and liquids taste to them. Now, findings from Monell reveal that a person's sensitivity to bitter taste is shaped not only by which taste genes that per... | intensity, it was not combined with gene expression in a final model. We provide the first experimental evidence that mRNA expression amounts of the PAV allele of the TAS2R38 taste receptor gene correlate with sensory perception of bitterness and with dietary habits in humans. PAV-TAS2R38 expression was detected in the... | [4.0, 5.0, 5.0, 4.0, 3.0] | Medicine | train | 4.2 | news | http://www.sciencedaily.com/releases/2013/09/130911184403.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29 |
10.1098/rsif.2019.0183 | Medicine_444 | Those with trichromatic (normal) vision, on the other hand, were very good at breaking camouflage. | The result, that trichromatic vision is more effective at breaking camouflage, seems to run counter to oft-quoted temperate forest trichromat temperate forest dichromat semi-arid desert trichromat semi-arid desert dichromat historical accounts of the military value of dichromatic observers and contemporary theories for... | Also, during testing with humans, they found that observers with dichromatic vision (color blindness) took longer to spot strongly colored animals. Those with trichromatic (normal) vision, on the other hand, were very good at breaking camouflage. They suggest their network could be a useful tool for better understandin... | Consequently this does not account for the difference between simulated dichromat and trichromat reaction times. The result, that trichromatic vision is more effective at breaking camouflage, seems to run counter to oft-quoted temperate forest trichromat temperate forest dichromat semi-arid desert trichromat semi-arid ... | [2.0, 5.0, 3.0, 5.0] | Medicine | train | 4 | news | http://ct.moreover.com/?a=39338408762&p=1pl&v=1&x=pliWAwUPbz0xbXd7c5wOLg |
10.1038/s41598-018-29405-7 | Medicine_445 | The team found that the greatest perception biases emerged when majority and minority groups were disproportionate in size, and when nodes of the same group were highly connected to each other. | Overall, despite the fact that in highly segregated networks the degree exponent and ranks of groups show similar behaviour, the ability of minority nodes to receive information from majority and vice versa decreases dramatically due to the split of the network. | Based on the position of an individual node within the network, the researchers predicted different perception biases would arise depending on two network properties: the relative sizes of the majority and minority groups, and their level of homophily (the extent to which like nodes connected to like). The team found t... | In addition, information is transmitted faster among minority nodes in high homophily due to a smaller number of nodes and thus shorter transmission paths, resembling rumor spreading in a small village. Overall, despite the fact that in highly segregated networks the degree exponent and ranks of groups show similar beh... | [2.0, 3.0, 2.0, 3.0, 4.0] | Medicine | train | 2.8 | news | http://ct.moreover.com/?a=39932111786&p=1pl&v=1&x=PKCnqR6uJrrrbBZhiSe8GQ |
10.1016/j.ajhg.2018.10.007 | Medicine_446 | "Our findings uncover, for the first time, a mechanism for the genesis of this abnormality and link the causal factors involved in recurrent molar pregnancies, miscarriages, and male and female infertility to mutations in three genes." | In TOP6BL/C11orf80, we found in one woman (ID 10), with one miscarriage and two HMs, a 1-bp insertion, c.783dup (p.Glu262*) in a homozygous state (Figure 2A , Table S4 ). | Long-standing mystery
"Our findings add three new genes to the list of mutations leading to fetal loss and will allow for more DNA testing for patients in order to prevent the recurrence of molar pregnancies and provide better genetic counseling and management for couples," says lead author Rima Slim, an associate pro... | Using RT-PCR on total RNA from a LCL from the proband 880, we found that the invariant splice site mutation, c.1196þ1G>A, leads to a smaller cDNA fragment that corresponds to the skipping of exon 11 ( Figure 1D ) located in one of the two predicted Armadillo-type fold domains ( Figure 1E ). In TOP6BL/C11orf80, we found... | [4.0, 2.0, 3.0, 4.0, 2.0] | Medicine | train | 3 | news | https://www.futurity.org/molar-pregnancy-miscarriage-genes-1917792/ |
10.1136/esmoopen-2017-000250 | Medicine_447 | Cancer survivors naturally age faster than others who haven't had cancer, and are more likely to develop long-term health problems related to aging while they're still relatively young, the study authors said. | We found multiple biological process of ageing at the cellular level and their association with cancer therapies, as well as with clinical effects. | Cancer survivors naturally age faster than others who haven't had cancer, and are more likely to develop long-term health problems related to aging while they're still relatively young, the study authors said. Survivors also are more likely to become frail as the years pass. Childhood cancer survivors' estimated life e... | We found multiple biological process of ageing at the cellular level and their association with cancer therapies, as well as with clinical effects. The direct effects of various chemotherapies and radiation on telomere length, senescent cells, epigenetic modifications and microRNA were found. Long-term follow-up of can... | [5.0, 2.0, 4.0, 2.0, 4.0] | Medicine | train | 2 | news | http://ct.moreover.com/?a=32822546106&p=1pl&v=1&x=tiTNu_73pWjRQlX-YijqIg |
10.1126/science.1244797 | Medicine_448 | "In comparison, RAD data show an average GCR dose equivalent rate of 1.8 millisieverts per day on the journey to Mars, when RAD measured the radiation inside the spaceship." | The RAD surface measurements provide a baseline for inferring the flux in these more shielded environments (by validating and anchoring transport models) and thus the foundation for understanding the limits to preservation of organic matter in the soil and rocks of Gale crater. | "The RAD surface radiation data show an average GCR dose equivalent rate of 0.67 millisieverts per day from August 2012 to June 2013 on the Martian surface," said Hassler. "In comparison, RAD data show an average GCR dose equivalent rate of 1.8 millisieverts per day on the journey to Mars, when RAD measured the radiati... | The radiation environment on Mars may also play a key role in the chemical alteration of the regolith and martian rocks over geologic time scales, affecting the preservation of organics, including potential organic biosignatures of the ancient martian environment . The RAD surface measurements provide a baseline for in... | [3.0, 2.0, 3.0, 2.0] | Medicine | train | 2.5 | news | http://www.sciencedaily.com/releases/2013/12/131209181133.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29 |
10.1038/s41598-018-25573-8 | Medicine_45 | "The lack of toxic effect of nanoparticle loaded doxorubicin was associated with specific delivery of doxorubicin to the tumor. | The color of liver, intestine and kidney was quite different. | In contrast, injection of free doxorubicin caused widespread organ damage, even when less amount was administered," write the investigators. "The lack of toxic effect of nanoparticle loaded doxorubicin was associated with specific delivery of doxorubicin to the tumor. Furthermore, we observed excellent tumor accumulati... | 5 left picture) . The color of liver, intestine and kidney was quite different. Kidney shape is altered and spleen shrank and could not be detected. | [1.0, 1.0, 2.0] | Medicine | train | 1.333333 | news | http://ct.moreover.com/?a=34218407527&p=1pl&v=1&x=TZ9cA3HHZNB3jHckRRSErA |
10.1177/0146167214565055 | Medicine_450 | Superstitions, by and large, apply to performance goals. | We suggest that this internal sense of judgment and control for learning goals means that people do not believe that superstition (contingent on external forces such as luck) will facilitate the achievement of learning goals, and will not use superstitious behavior to facilitate their achievement. | How well you do is up for debate. Superstitions, by and large, apply to performance goals. When we're at home studying, and the light from our desk lamp is illuminating all our missed math problems, we don't run to the dresser to fish out a pair of smelly socks -- we'd have no reason to. | Intrinsic motivation leads to a perception of internal (rather than external) locus of control , which is consistent with the idea that learning goals are judged internally-by oneself. We suggest that this internal sense of judgment and control for learning goals means that people do not believe that superstition (cont... | [3.0, 5.0, 3.0, 2.0, 4.0] | Medicine | train | 3.4 | news | http://www.medicaldaily.com/superstition-comes-lacking-sense-control-science-behind-good-luck-charms-319098 |
10.1186/1742-9994-10-39 | Medicine_451 | Dingoes and red foxes are temporarily suppressed, while feral cats and goannas are not affected, which suggests that careful planning of culls, around calving time to save livestock from attacks, should not in the long-term harm of other animals in the ecosystem. | Rarely did any of these occur for any mesopredator at any site. | The culling of dingoes in Australia to protect livestock does not open the way for other predators to take their place finds research in BioMed Central's open access journal Frontiers in Zoology by the Invasive Animals CRC in Australia. Dingoes and red foxes are temporarily suppressed, while feral cats and goannas are ... | If either fox, cat or goanna populations gained an overall benefit from lethal dingo control, then (1) overall mean mesopredator PTI should have been higher in baited areas, and/ or (2) mesopredator PTI values should have increased in baited areas following baiting, and/or (3) mesopredator PTI trends should have diverg... | [1.0, 1.0, 2.0, 2.0] | Medicine | train | 1.5 | news | http://www.sciencedaily.com/releases/2013/07/130710114324.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29 |
10.1007/s10071-013-0672-5 | Medicine_453 | Apparently, chimpanzee mothers endow their offspring with important social skills. | Weighing these alternative explanations, however, we would argue that the deprivation of maternal care would be a more likely explanation of the presented results than the early trauma suffered by the orphaned chimpanzees. | Apparently, chimpanzee mothers endow their offspring with important social skills. It may not come as a surprise, but mother chimpanzees seem to be important for the development of social skills in young chimpanzees. "Orphaned chimpanzees had more difficulties to successfully coordinate their social play interactions,"... | Finally, it might have been the case that early separation trauma intrinsically caused the orphaned chimpanzees to become less socially attuned, irrespective of the subsequent absence of maternal care. Weighing these alternative explanations, however, we would argue that the deprivation of maternal care would be a more... | [3.0, 1.0, 4.0, 2.0, 4.0] | Medicine | train | 2.8 | news | http://www.sciencedaily.com/releases/2013/09/130906114300.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29 |
10.1542/peds.2013-3406 | Medicine_454 | "However, association does not mean causation, and this is very important for the woman to understand." | Adjusting, rather than restricting, for maternal mental health yielded similar findings. | "This study shows an association between the use of SSRIs and autism spectrum disorders," says Dr. Ariela Frieder of Montefiore Medical Center in New York. "However, association does not mean causation, and this is very important for the woman to understand." It is also important to contextualize how many cases of auti... | The pattern was similar among boys in the anxiety/mood disorder subset, but with low precision (102 ASD, 29 DD, 50 TD). Adjusting, rather than restricting, for maternal mental health yielded similar findings. Results were similar, although attenuated. | [1.0, 2.0, 1.0, 1.0, 1.0] | Medicine | train | 1.2 | news | http://www.thedailybeast.com/articles/2014/04/17/new-study-shows-link-between-ssris-and-autism.html |
10.1073/pnas.1606526113 | Medicine_458 | For instance, it can take into account a whole range of factors that are decisive for hydrology, such as rain and snow volume, evaporation, groundwater and also the ways in which glaciers expand and experience changes in volume. | Modeling studies at a high spatiotemporal resolution and degree of process complexity are crucial to assess the impact of climate change on the hydrological balance of high-altitude catchments and to refine the projections of the coarser-scale models . | New model also enables regional predictions
"What's new and unique about our model is that it can realistically illustrate many different processes," says Ragettli. For instance, it can take into account a whole range of factors that are decisive for hydrology, such as rain and snow volume, evaporation, groundwater an... | Given the multitude of control factors, often acting at relatively small scales, current projections of global glacier change models do not constrain the mechanisms underlying the variations in river flow from high-altitude catchments well . Modeling studies at a high spatiotemporal resolution and degree of process com... | [4.0, 4.0, 4.0, 4.0, 3.0] | Medicine | train | 3.8 | news | http://healthmedicinet.com/news/opposing-mountain-ranges/ |
10.1073/pnas.1407535111 | Medicine_459 | We find that there is some truth to this: lower expectations make it more likely that an outcome will exceed those expectations and have a positive impact on happiness. | However, self-reported overall happiness did not increase between the beginning and the end of the experiment [initial happiness: 60 ± 18, final happiness: 54 ± 20 (mean ± SD), t(25)= −1.0, P = 0.33; Fig. | In real-world situations, the rewards associated with life decisions such as starting a new job or getting married are often not realised for a long time, and our results suggest expectations related to these decisions, good and bad, have a big effect on happiness. We find that there is some truth to this: lower expect... | Prizes up to £3 were sufficient to elicit changes in happiness with root-mean-square differences between successive ratings of 17 ± 8 (mean ± SD, range 6-43). However, self-reported overall happiness did not increase between the beginning and the end of the experiment [initial happiness: 60 ± 18, final happiness: 54 ± ... | [2.0, 4.0, 2.0, 1.0, 1.0] | Medicine | train | 2 | news | http://www.healthcanal.com/mental-health-behavior/53795-equation-to-predict-happiness.html |
10.1001/jama.2018.20578 | Medicine_46 | In other words, researchers wrote, approximately one in 200 people treated with aspirin would experience significant bleeding. | 6 This study showed that when analysis was restricted to populations with observation-derived 10-year cardiovascular event rate estimates of 10% or more, aspirin use was associated with an absolute risk decrease of 0.51% (5% CI, 0.06%-0.3%) for the cardiovascular composite outcome, but an absolute risk increase of 0.64... | Compared to those who didn't take aspirin, aspirin use was associated with a 43 percent increase of major bleeding events. In other words, researchers wrote, approximately one in 200 people treated with aspirin would experience significant bleeding. To prevent a single heart attack, stroke or cardiovascular death, appr... | However, the use of cardiovascular risk scores tends to overestimate an individual's true risk, 32 with poor agreement between different cardiovascular risk calculators. 6 This study showed that when analysis was restricted to populations with observation-derived 10-year cardiovascular event rate estimates of 10% or mo... | [3.0, 1.0, 4.0, 4.0] | Medicine | train | 4 | news | http://ct.moreover.com/?a=38330617260&p=1pl&v=1&x=SFs6QnNOIxtCukPluYBeGg |
10.1111/cdev.12344 | Medicine_460 | Our study reveals some of the negative implications of higher rates of teachers' symptoms of depression for students." | Teachers' depressive symptoms were negatively associated with quality of CLE, and quality of CLE mediated the association between depressive symptoms and student achievement. | Our study reveals some of the negative implications of higher rates of teachers' symptoms of depression for students." The students most vulnerable to the negative effects of their teachers' depression were those who were already struggling in math, suggesting that the children who needed to improve the most were less ... | This depended on students' fall mathematics scores; students who began the year with weaker math skills and were in classrooms where teachers reported more depressive symptoms achieved smaller gains than did peers whose teachers reported fewer symptoms. Teachers' depressive symptoms were negatively associated with qual... | [3.0, 4.0, 1.0, 5.0] | Medicine | train | 4 | news | http://psychcentral.com/news/2015/02/12/teachers-depression-linked-to-poor-student-performance/81153.html |
10.1177/0141076815593403 | Medicine_461 | If the program is successful, these rates should fall over time, indicating that mammography screening is contributing effectively to reducing breast cancer mortality. | Our re-calculations of Swedish trial revealed that risks of breast cancer death were similar for cancers found during the intervention and the post-intervention periods, indicating that reductions in the risk of breast cancer death also applied to cancer cases diagnosed when screening (or absence of screening) was the ... | Early detection reduces the risk of being diagnosed with an advanced cancer that is often deadly. If the program is successful, these rates should fall over time, indicating that mammography screening is contributing effectively to reducing breast cancer mortality. Moreover, with increased screening, more rapid and mor... | The compensation argument invoked by Swedish trial investigators 6, is thus not tenable. Our re-calculations of Swedish trial revealed that risks of breast cancer death were similar for cancers found during the intervention and the post-intervention periods, indicating that reductions in the risk of breast cancer death... | [2.0, 4.0, 1.0, 3.0, 5.0] | Medicine | train | 4 | news | http://www.oncologynurseadvisor.com/benefits-of-mammography-may-be-statistically-overestimated/article/428234/ |
10.1002/pon.4156 | Medicine_462 | In the study, more physical activity was associated with higher levels of self-confidence, lower distress and less fatigue, which in turn is associated with lower levels of perceived memory impairment. | Finally, higher levels of distress (β = À0.31) and fatigue (β = À0.18) were associated with lower Frequency of Forgetting scores which is indicative of greater SMI. | The study will be published July 8 in the journal Psycho-Oncology. In the study, more physical activity was associated with higher levels of self-confidence, lower distress and less fatigue, which in turn is associated with lower levels of perceived memory impairment. "We found moderate to vigorous physical activity ac... | Survivors who reported higher levels of distress also reported higher levels of fatigue (β = 0.63). Finally, higher levels of distress (β = À0.31) and fatigue (β = À0.18) were associated with lower Frequency of Forgetting scores which is indicative of greater SMI. Additionally, the indirect paths from physical activity... | [3.0, 3.0, 5.0, 1.0, 1.0] | Medicine | train | 3 | news | http://healthmedicinet.com/news/moderate-to-vigorous-physical-activity-linked-to-improved-memory-in-breast-cancer-survivors/ |
10.1038/s41541-019-0118-4 | Medicine_463 | "We're excited by these findings, because they seem to suggest that we can use the body's own immune system to make antibodies against these tangles, and that these antibodies actually bind and clear these tau tangles," said Ph.D. student Nicole Maphis at UNM's Biomedical Sciences department in a press release. | Therefore, we believe that this report provides compelling evidence that a VLP-based immunotherapy approach can be beneficial in preventing tau pathology and could be applicable to diverse human tauopathies, such as Alzheimer's disease (AD), frontotemporal dementia (FTD), traumatic brain injury (TBI), and chronic traum... | When the mice fed the vaccine were put in maze like test scenarios, they fared better than mice who had not received treatment. "We're excited by these findings, because they seem to suggest that we can use the body's own immune system to make antibodies against these tangles, and that these antibodies actually bind an... | Reduction in pathological consequences following this immunotherapy translated into improved cognitive function using well-established measurements of delay-dependent and spatial learning and memory tests. Therefore, we believe that this report provides compelling evidence that a VLP-based immunotherapy approach can be... | [2.0, 2.0, 3.0, 1.0] | Medicine | train | 2 | news | http://ct.moreover.com/?a=39458834280&p=1pl&v=1&x=a6UcobFlOESXjLG2kIvzhA |
10.1126/science.1261498 | Medicine_464 | "If we can use computational tricks to predict the host, we can explore that viral-host linkage. | Beyond core and pan metagenomic analyses, PCs also provide a metric for viral community diversity comparisons (Fig. | "None of these genomic features is really a smoking gun per se, but combining them led to a robust detection of 'new' viruses - viruses we did not have in the database, but can identify because they have capsid genes and a viral organization," he said. "If we can use computational tricks to predict the host, we can exp... | Indeed, nichedifferentiation has been observed in viromes sampled across these oceanic zones in the POV data set (28), and similar findings were observed in the microbial metagenomic counterparts from the Tara Oceans Expedition (25). Beyond core and pan metagenomic analyses, PCs also provide a metric for viral communit... | [4.0, 1.0, 3.0, 1.0, 3.0] | Medicine | train | 2 | news | http://www.technology.org/2015/08/17/%e2%80%8bfishing-expedition-nets-nearly-tenfold-increase-number-sequenced-virus-genomes/ |
10.1038/s41467-018-04133-8 | Medicine_465 | The results of this study provide new insight into the channel function. | It is important to note that obtaining a linear release profile for a molecule carrying a charge of sign opposite to that of the channel surfaces is trivial: as a matter of fact, it is a previously unreported achievement. | In the context of drug delivery, this platform is considered 'drug-agnostic,' which simply means the same membrane technology can be used for a wide spectrum of drugs, and just the size of the channel is what needs to be customized. The results of this study provide new insight into the channel function. Upon putting t... | 3 and Supplementary Fig. It is important to note that obtaining a linear release profile for a molecule carrying a charge of sign opposite to that of the channel surfaces is trivial: as a matter of fact, it is a previously unreported achievement. Figure 2b exhibits release curves of anionic cefazolin, (3-aminosalicylic... | [4.0, 3.0, 5.0, 1.0, 4.0] | Medicine | train | 4 | news | http://healthmedicinet.com/news/discovery-will-impact-design-of-drug-delivery-systems-at-the-molecular-level/ |
10.1038/s41588-018-0135-7 | Medicine_466 | The study has also generated the first comprehensive database of which microbes are associated with which chemical metabolites in the gut. | 2b ), and one metabolite, phytanate, was significantly different between the oldest and youngest deciles (P = 5.0 × −3 ; Fig. | On the back of the study researchers have built a gut metabolome bank that can help other scientists engineer bespoke and ideal gut environments that efficiently process and distribute fat. The study has also generated the first comprehensive database of which microbes are associated with which chemical metabolites in ... | However, a multivariate partial-least-squares discriminant analysis incorporating all the common 570 metabolites was able to distinguish the oldest decile (> 75 years) from the youngest decile (< 56 years) of the study population (area under the curve = 0.71, P = 6.8 × −6 ; Fig. 2b ), and one metabolite, phytanate, was... | [2.0, 2.0, 1.0, 1.0, 1.0] | Medicine | train | 1.4 | news | http://ct.moreover.com/?a=34164034859&p=1pl&v=1&x=zrs5-TWfNa6KsyzWLpB7FQ |
10.1126/sciadv.1400155 | Medicine_467 | However, the findings also revealed that the markings of male and female birds have become less different over time, as the animals attempt to blend in with their surroundings to hide themselves from predators. | Plumage with more UV/blue/green reflectance (higher PC2) in both sexes was associated with larger body mass, sedentary behavior, semiprecocial young (that is, gulls with white UV-reflecting plumage), male parental care, and nesting in trees (table S2) . | However, the findings of the research team are the opposite. However, the findings also revealed that the markings of male and female birds have become less different over time, as the animals attempt to blend in with their surroundings to hide themselves from predators. The research found that natural selection, which... | Note that these are general characteristics, because some of these variables rarely co-occur (for example, only 5% of species had both altricial young and no male care). Plumage with more UV/blue/green reflectance (higher PC2) in both sexes was associated with larger body mass, sedentary behavior, semiprecocial young (... | [3.0, 4.0, 2.0, 1.0, 2.0] | Medicine | train | 2.4 | news | http://www.techtimes.com/articles/43011/20150330/evolution-of-bird-plumage-color-also-affected-by-predation.htm |
10.1088/2057-1739/aa83bf | Medicine_468 | Dr Torga said: "The system allows us to carry out continuous observation of the interactions of multiple cell types at cell-by-cell resolution, and observe the development of drug resistance in the cancer cells in real time. | The engineered microenviron ment device allows at the quantitative study at the singlecell level of signaling dynamics and gene expres sion by monitoring in realtime the interactions of multiple cell types in response to each other as well as varying environmental conditions over time. | The team's system acts as an 'evolution accelerator', allowing the study of key interactions between host cells and cancer cells, and their response to the drug, to be carried out in a much shorter timeframe. Dr Torga said: "The system allows us to carry out continuous observation of the interactions of multiple cell t... | Population dynamics is qualitatively different from singlecell behaviors. The engineered microenviron ment device allows at the quantitative study at the singlecell level of signaling dynamics and gene expres sion by monitoring in realtime the interactions of multiple cell types in response to each other as well as var... | [4.0, 3.0, 1.0, 4.0, 2.0] | Medicine | train | 2.8 | news | http://healthmedicinet.com/news/cell-culture-system-could-offer-cancer-breakthrough/ |
10.1126/science.1261713 | Medicine_469 | I'll try to update this piece with a link when it becomes available.) | Contradictions were noted between the locations of maxima reported from ground-based observations and maps inferred by PFS and TES from Mars orbit. | (Zahnle has critical commentary on the new Curiosity results as well, but as of the time I'm writing this article, it wasn't yet linked from the Science website. I'll try to update this piece with a link when it becomes available.) That reactivity paradoxically is what makes its sudden coming and going mysterious. | (13) . Contradictions were noted between the locations of maxima reported from ground-based observations and maps inferred by PFS and TES from Mars orbit. The plume results (13) were questioned (22) on the basis of a possible misinterpretation from methane lines whose positions coincided with those of terrestrial isoto... | [1.0, 2.0, 1.0, 1.0, 1.0] | Medicine | train | 1.2 | news | http://www.thedailybeast.com/articles/2014/12/16/methane-on-mars-life-or-just-gas.html |
10.1001/jama.2018.20578 | Medicine_47 | Over the thousands of people included in the meta-study, those who took daily aspirin had a 0.38 percent lower absolute risk of heart attacks, strokes, or death from cardiovascular events. | 25 However, the 10-year myocardial infarction event rate (19.2%) justified its inclusion in the high-risk subgroup. | Now the picture is a little more clear. Over the thousands of people included in the meta-study, those who took daily aspirin had a 0.38 percent lower absolute risk of heart attacks, strokes, or death from cardiovascular events. At the same time, a daily aspirin habit was associated with a 0.47 percent higher absolute ... | The estimated population 10-year risk of the primary composite cardiovascular outcome was less than 10% in 6 studies enrolling 112 566 participants (median, 6.8%; range, 2.6%-8.1%) 6, 23, 24, 26 and was at least 10% in 7 studies enrolling 50 383 participants (median, 12.7%; range, 10.2%-15.9%). 25 However, the 10-year ... | [2.0, 2.0, 1.0] | Medicine | train | 1.666667 | news | http://ct.moreover.com/?a=38333931091&p=1pl&v=1&x=RFNXfRDC7W6ykWiKhqzpYQ |
10.1073/pnas.1318801111 | Medicine_470 | According to Bergouignan, who has tried the experiment many times, this creates a very strong effect. | The experiments revealed two important findings. | The out-of-body experience was heightened by the illusion of stick touching the students as they watch a different stick point at the camera from a similar angle. According to Bergouignan, who has tried the experiment many times, this creates a very strong effect. Bergouignan explained that since the student's location... | Taken together, these imaging results associate out-of-body-induced episodic memory impairment with altered hippocampal recruitment. The experiments revealed two important findings. First, the behavioral results showed that episodic encoding of life events requires perceiving the world from the first-person perspective... | [1.0, 3.0, 1.0, 1.0, 2.0] | Medicine | train | 1.6 | news | http://www.hngn.com/articles/26248/20140312/brain-struggles-recalling-out-of-body-memories-study-finds.htm |
10.1016/j.cub.2014.12.023 | Medicine_472 | Dr Webb added: "When we concentrate on those groups of animals and plants which are best known, and where estimates of extinction risk are likely to be most reliable, the difference between marine and non-marine species disappears. | We define 11 marine and eight non-marine groups as well assessed by the IUCN (of which six and seven, respectively, are also well described; Table 1 ). | This assessment means that species have been checked against a list of criteria published by the International Union for the Conservation of Nature, a time-consuming process that has been completed for only three per cent of marine species, with no assessments at all in three quarters of the major groups of marine anim... | 16.8% marine), and proportions of predicted total species numbers (10.0% non-marine cf. We define 11 marine and eight non-marine groups as well assessed by the IUCN (of which six and seven, respectively, are also well described; Table 1 ). These contain 42.7% of all described and 98.8% of all assessed marine species an... | [3.0, 3.0, 3.0, 5.0, 2.0] | Medicine | train | 3.2 | news | http://www.sciencedaily.com/releases/2015/01/150129125544.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_science+%28ScienceDaily%3A+Top+Science+News%29 |
10.1126/scitranslmed.3006055 | Medicine_473 | They found that all of these drugs were safe after six hours of treatment, but longer-term treatment of about four days caused the mitochondria to malfunction. | These findings are analogous to our previous work in bacteria, in which we showed that clinically relevant doses of bactericidal antibiotics induce a common oxidative damage pathway (4). | They found that all of these drugs were safe after six hours of treatment, but longer-term treatment of about four days caused the mitochondria to malfunction. Kalghatgi and Spina then did a series of biochemical tests, which showed that the same three antibiotics damaged the DNA, proteins and lipids of cultured human ... | Second, we demonstrate that these deleterious effects are produced by clinically relevant doses of bactericidal antibiotics, both in cell culture and in mice. These findings are analogous to our previous work in bacteria, in which we showed that clinically relevant doses of bactericidal antibiotics induce a common oxid... | [4.0, 1.0, 1.0, 4.0, 2.0] | Medicine | train | 2 | news | http://www.healthcanal.com/immune-system/40496-dodging-antibiotic-side-effects.html |
10.1098/rsbl.2013.0974 | Medicine_474 | Chimpanzees can and do use these same muscle movements when making an angry face, but their facial expressions were not linked to the time they spent trying to get into the box. | Humans exhibit a motivation for, and level of, cooperation in their social interactions that is unique among primate species , and so, in this context, we might expect human facial expressivity to exhibit some important differences from other primates. | The results showed that the longer the children persisted at trying to open the box, the more they displayed a "determination face" -- essentially, pressed-together lips and a raised chin, the sort of muscle motion that happens if you stick out your lower lip. Chimpanzees can and do use these same muscle movements when... | Overall, physical similarity of the main facial expression configurations, however, may obscure important differences in how facial expression is actually used. Humans exhibit a motivation for, and level of, cooperation in their social interactions that is unique among primate species , and so, in this context, we migh... | [2.0, 3.0, 4.0, 3.0, 4.0] | Medicine | train | 3.2 | news | http://www.scientificamerican.com/article/game-face-evolved-as-plea-for-help/?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciam%2Fevolution+%28Topic%3A+Evolution%29 |
10.1098/rspb.2014.2449 | Medicine_475 | The team claim that the massive increase in Holopedium will have a major impact on the ecosystem and the jelly could also block drinking water filtration systems. | Many environmental changes other than Ca decline influence zooplankton, though they are unlikely to be the dominant factor explaining the rise of Holopedium. | Holopedium only require one tenth of the calcium of Daphnia and their jelly coating also protects them from predators. The upsurge in Holopedium has led to the water becoming increasingly gelatinous. The team claim that the massive increase in Holopedium will have a major impact on the ecosystem and the jelly could als... | Additional data on nutritional thresholds and phytoplankton community composition would help to test these explanations. Many environmental changes other than Ca decline influence zooplankton, though they are unlikely to be the dominant factor explaining the rise of Holopedium. For example, the SEM suggests that recent... | [3.0, 2.0, 3.0, 2.0, 3.0] | Medicine | train | 2.6 | news | http://www.scientificamerican.com/article/plankton-culprit-turns-clear-lakes-to-jelly/ |
10.1016/j.biopsych.2013.11.018 | Medicine_477 | Senior author Dr. Matcheri Keshavan, a Professor at Harvard Medical School, describes their results: "The main finding was that psychotic disorders are characterized by reduced folding of the cortex in key brain regions such as the cingulate cortex (a brain region involved in thinking and emotions). | Although the direct BP-SZ comparison yielded no significant results, these findings of disparate gyrification profiles relative to controls may lend some support for the divides between psychotic diagnoses such as schizophrenia, schizoaffective disorder, and psychotic bipolar disorder. | "The cortical folding pattern itself may not be so important, but the disturbances in connections between brain regions implicated by the changes in cortical folding could provide critical clues to deficits in the integrity of brain circuits that contribute to symptoms and functional impairment in schizophrenia," comme... | Psychotic bipolar disorder patients had only one region of significant difference compared to controls. Although the direct BP-SZ comparison yielded no significant results, these findings of disparate gyrification profiles relative to controls may lend some support for the divides between psychotic diagnoses such as sc... | [4.0, 1.0, 2.0, 2.0, 4.0] | Medicine | train | 2 | news | http://www.sciencedaily.com/releases/2014/09/140911092915.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29 |
10.1038/s41467-017-00618-0 | Medicine_478 | The paper, with first author Dr Mian Bi and co-senior author Dr Ke, is the first to show a direct role of tau in brain damage after stroke. | Accordingly, treatment of primary neurons with bicuculline or KCl to increase synaptic glutamate levels and induce excitotoxic signaling 38 resulted in ERK phosphorylation and IEGs induction in tau +/+ but not tau −/− cells ( Fig. | Drug development in this space should consider stroke as a disease that you can treat by targeting tau," Dr Ke added. The paper, with first author Dr Mian Bi and co-senior author Dr Ke, is the first to show a direct role of tau in brain damage after stroke. It demonstrates profound protection from brain damage, of more... | This is in line with a failure to activate ERK downstream of synaptic NMDARs, while ERK inhibition mediated by extra-synaptic NMDARs 36 remained intact in tau −/− neurons. Accordingly, treatment of primary neurons with bicuculline or KCl to increase synaptic glutamate levels and induce excitotoxic signaling 38 resulted... | [2.0, 4.0, 2.0, 2.0, 1.0] | Medicine | train | 2.2 | news | http://healthmedicinet.com/news/study-offers-a-new-mindset-in-the-search-for-stroke-therapies/ |
10.1007/s10935-017-0491-6 | Medicine_479 | Encouraging even small amounts of exercise is important, Bellettiere added, because of its compounding effect in people's lives: If they take the stairs early in the day, they may make similar healthy choices later in the day. | Our results and these recommended modifications to the built environment are consistent with the principles of behavior in that both prompts for behavior and contingencies of reinforcement increase stair use . | "It's the first time this kind of effect has been shown at an airport." Encouraging even small amounts of exercise is important, Bellettiere added, because of its compounding effect in people's lives: If they take the stairs early in the day, they may make similar healthy choices later in the day. Also, when people see... | This result led the CDC to recommend improved and aesthetically pleasing stairwells for all their facilities worldwide . Our results and these recommended modifications to the built environment are consistent with the principles of behavior in that both prompts for behavior and contingencies of reinforcement increase s... | [3.0, 2.0, 4.0, 3.0, 3.0] | Medicine | train | 3 | news | http://healthmedicinet.com/news/making-healthier-decisions-step-by-step/ |
10.1210/en.2015-2036 | Medicine_48 | The research highlights a direct link between circulating vitamin D levels and the expression of a gene called ID1, known to be associated with tumor growth and breast cancer metastasis. | We also discovered that, although circulating 25(OH)D has many systemic effects (1), a critical mechanism for vitamin D signaling to inhibit BCa progression is a tumor autonomous activity that suppresses Id1 expression. | The research highlights a direct link between circulating vitamin D levels and the expression of a gene called ID1, known to be associated with tumor growth and breast cancer metastasis. The finding builds upon several previous studies suggesting that low levels of vitamin D not only increase a person's risk of develop... | Further, we discovered that attenuated vitamin D signaling due to Vdr ablation enhances tumor progression and, importantly, is sufficient to enable metastases, which are the primary cause of treatment failure and death for patients with BCa. We also discovered that, although circulating 25(OH)D has many systemic effect... | [5.0, 2.0, 3.0, 3.0, 3.0] | Medicine | train | 3.2 | news | http://www.science20.com/news_articles/vitamin_d_deficiency_contributes_to_spread_of_breast_cancer_in_mice_stanford_study_finds-167109 |
10.1186/s13027-016-0049-x | Medicine_480 | If the former is true, Wang says simple antibiotics may prove useful or researchers can develop other therapeutic approaches for esophageal cancer utilizing genetic technology to target the P. gingivalis and ultimately destroy the cancer cells. | While the presence of P. gingivalis was not significantly associated with age, gender, or smoking history of the patients, the presence of P. gingivalis was positively related to differentiation, lymph node metastasis and the TNM stage of ESCC (p < 0.05). | According to Wang, there are two likely explanations: either ESCC cells are a preferred niche for P. gingivalis to thrive or the infection of P. gingivalis facilitates the development of esophageal cancer. If the former is true, Wang says simple antibiotics may prove useful or researchers can develop other therapeutic ... | If we set the samples with IHC scores more than 1 as P. gingivalis positive, the sensitivity and specificity of IHC would be 94.3 and 96.6 %, respectively (Kappa = 0.882; p < 0.001, Additional file 2: Table S1), showing excellence concordance between IHC and qRT-PCR for the detection of P. gingivalis infection in the c... | [3.0, 4.0, 2.0, 2.0, 4.0] | Medicine | train | 3 | news | http://healthmedicinet.com/news/p-gingivalis-could-be-a-novel-risk-factor-for-esophageal-cancer/ |
10.1016/j.ijlp.2009.01.002 | Medicine_481 | Sociopaths, he suggested, are capable of feeling remorse or guilt. | Moreover, our findings do not support the hypothesis of an association between the interpersonal domain of psychopathy and greater cognitive abilities. | So, about all we can say is that around 1% of the male population would receive a score of 30" on the extended exam or a score of 18 on a shorter version. Sociopaths, he suggested, are capable of feeling remorse or guilt. Lilienfeld said by email that the oft-cited 1 percent figure, rooted in research employing Hare's ... | However, the negative association with the Affective factor was not confirmed by our study. Moreover, our findings do not support the hypothesis of an association between the interpersonal domain of psychopathy and greater cognitive abilities. It has to be considered, however, that our measure of intelligence was more ... | [2.0, 1.0, 3.0, 2.0, 2.0] | Medicine | train | 2 | news | http://ct.moreover.com/?a=33688948919&p=1pl&v=1&x=BleRJIQwQoEXWJSTnroQ8g |
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