text stringlengths 16 69.9k |
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A/N: Sorry for skipping on Whisper again. I’m going to try and do a load of writing on it and Haventon this weekend.
“I’d definitely say wait another day,” Lucas said after he’d poked at Andrew and Naria’s bond extensively. “It’s not trying to revert so we don’t need to rush it and risk doing you both damage. Are you getting used to it being bound less tightly?”
“Yes,” Andrew said even as Naria nodded.
“That’s good,” Lucas said. “You should sleep better tonight, then. If you want, I can get Ishleen to nudge you to make sure you do.”
Andrew hesitated. Somehow he was more comfortable with the thought of a speaker like Ishleen nudging him than another human doing it, but it was still an uncomfortable thought.
Naria seemed to have no such reservations. “I think that’s a great idea,” she said. “I accept.” She gave Andrew a sly look. “I don’t know if Drew will.”
Lucas gave Andrew a thoughtful look. “Yes, you do value you privacy, don’t you? Ish won’t do anything more than help you sleep, I promise.â€
“It’ll just be like when that healer Simon helped you sleep,†Naria said. “You should consider it.â€
Andrew gave a wry smile. “I doubt I would have let him do that if I hadn’t been so exhausted but that’s a good point.†He closed his eyes thoughtfully. “Okay, let’s do it. I do need to sleep. I’ve too much to do to be sleep deprived.â€
“Great!†Lucas said. “I’ll go and get her while you two get ready for bed.â€
“But how how we going to do this?†Andrew asked suddenly. “She won’t fit up the stairs.â€
“No,†Lucas agreed. “Not even in resting form. I’m rather afraid we’ll have to carry you to your beds.â€
“Ah!†Andrew said. “Okay then.â€
***
When Andrew got back downstairs after getting into his nightclothes, the french windows had been opened to admit Ishleen. In her full form, the nightmare resembled a black Arabian mare with bat wings and was large enough to make the lounge seem crowded all on her own. As soon as he entered the lounge, Ishleen nuzzled Andrew.
Andrew gave her a thoughtful look. “You’re a nightmare, right? I’m not going too get bad dreams if you make me sleep?â€
“Drew!†Naria said as she entered the room wrapped in a dressing gown. “That’s a terrible, distrustful thing to ask. You should apologise to Ishleen.â€
Ishleen gave a neighing chuckle. “No, it’s a fair question, not an accusation. Causing bad dreams is what we’re known for and it would be counterproductive when you are trying to rest if my making you sleep caused nightmares as a side-effect.†She nuzzled Andrew again. “But it’s not all we can do. You’ll have good dreams, I promise.â€
“Ah, okay then,†Andrew said. “Thanks.â€
“You’re welcome,†Ishleen replied. “Now sit down so you don’t fall down when I do this.â€
Andrew did as she said and Ishleen touched her nose to his forehead. There was a moment of pleasant fogginess before everything went black. |
JZ suggested going out and laptopping in a public cafe etc as an easier route to productivity than home-officeing... gotta try it.
Snacks are of course incredibly important, nay, essential to the roleplaying experience. Being part of a balanced diet, it's essential to have representatives of all four basic food groups: sugar, salt, fat, and caffeine.
Interestingly, these are usually combined into the pairs (sugar, caffeine) - cola or other caffeinated fizzy drinks - and (salt, fat) - pizza, potato chips, other assorted snack foods. The pairing (sugar, fat), while perfectly valid - e.g. cakes, doughnuts, ice cream - is not seen anywhere near as much. And its counterpart (salt, caffeine) is just too bizarre to contemplate. |
About
The Swiss Society of Health Economics sggö aims to foster the promotion of science, research and scientific consultancy in health economics. It informs the public about health economic insights and represent them vis-à-vis Swiss parliaments and governments. ssgö communicates with other Swiss, national and international health economics associations. |
Like search_objects_GET() but does not set result values, only a total count. Useful for AJAX-y types of situations where you want to query for a total number of matches and create a pager but not actually retrieve any data. |
Chances are you’ve never really counted, but it might be worth starting, especially if weight is a concern. Because according to a new study, taking more time to chew could help you better control your weight.
Testing The Hypothesis
Chinese researchers tested this hypothesis by serving breakfast to thirty young men fourteen of whom were obese, and sixteen who were of normal weight. First, they watched to see if the obese guys chewed differently from their skinnier co subjects, and found that the obese men ate faster and chewed less.
Later, the researchers served up another meal and divided the participants into two groups: one that would chew each bite fifteen times, and another told to chew each bite forty times.
The more active chewers ended up eating around twelve percent fewer calories no matter if they were skinny or fat. The researchers suspect that more chewing helped lower levels of ghrelin a brain chemical that stimulates appetite and increased levels of a chemical that tells the brain when it’s time to stop eating.
Chewing The Sample
The study’s sample size was small, and previous studies along similar lines have had mixed results. So it’s probably not the case that more chewing, alone, can vanquish obesity. But it may be a piece of the puzzle.
Other studies have shown that eating without thinking about what’s going into your mouth can result in overeating. If more chewing leads to more mindful eating, then it could help you eat less.
Related Posts (Automatically Generated)
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Q:
Not Getting External Font in Android
I am not getting external font, from creating new class, where i defined external font.
FontStyle.Java
public class FontStyle extends Activity{
public final static String roboto_regular = "fonts/roboto_regular.ttf";
public Typeface font_roboto_regular = Typeface.createFromAsset(getAssets(),
roboto_regular);
}
and MainActivity.Java
public class MainActivity extends Activity {
FontStyle font_style;
@Override
public void onCreate(Bundle savedInstanceState) {
super.onCreate(savedInstanceState);
setContentView(R.layout.main);
fontStyling();
}
private void fontStyling() {
TextView test= (TextView) findViewById(R.id.tv_test);
test.setTypeface(font_style.font_roboto_regular );
}
I am getting this error or logcat:
java.lang.RuntimeException: Unable to start activity ComponentInfo{com.test/com.test.MainActivity}: java.lang.NullPointerException
please guy correct me: thanks in advance.
A:
first you will need to pass Activity context in FontStyle to access getAssets method. if FontStyle is not an Activity then no need to extends Activity to it. change your FontStyle class as:
public class FontStyle {
Context context;
public final static String roboto_regular = "fonts/roboto_regular.ttf";
public FontStyle(Context context){
this.context=context;
}
public Typeface getTtypeface(){
Typeface font_roboto_regular =
Typeface.createFromAsset(context.getAssets(),roboto_regular);
return font_roboto_regular;
}
}
Now change Activity code as to set Custom font for TextView :
public class MainActivity extends Activity {
FontStyle font_style;
@Override
public void onCreate(Bundle savedInstanceState) {
super.onCreate(savedInstanceState);
setContentView(R.layout.main);
font_style=new FontStyle(MainActivity.this);
fontStyling();
}
private void fontStyling() {
TextView test= (TextView) findViewById(R.id.tv_test);
test.setTypeface(font_style.getTtypeface());
}
|
[Substance abuse in recreational exercise].
Substance abuse has become increasingly widespread among athletes at sub competitive and recreational level, due in part to the lack of controls in form of doping tests. Hypertension and the many other side effects related to the illicit use of prescription drugs pose a substantial but often underestimated threat to public health. The symptoms are recognized late and are then mostly repressed or misjudged. Since the abuse is concealed to the doctor when help is finally sought, it results in extensive and expensive tests that can seldom lead to an effective treatment. Two case reports are presented to elaborate on this issue. |
Q:
How can I get the list of all google fonts WITHOUT using the API key?
Im making a wordpress theme with a feature to allow users to choose their own fonts from Google. Obviously because this is a wordpress theme there is no way to create a new API key for each installation.
All I need is the list of fonts in alphabetical order.
Bonus points if someone gives me a way to group them by category!
A:
Check out the developer API. You can query it for a list of the fonts. I'm not sure it categorises them, but you do get a bunch of details.
EDIT/ADDITION:
You only need an API key beyond usage limits, so depending on how many calls you make, you could just parse this JSON.
|
Q:
Copying an array of int8_t in C
I have the following:
int8_t rtp[size];
int8_t holding[size];
I want to copy the value in rtp into holding.
A:
Use memcpy() for simply copying.
This works regardless of the type of the objects.
Insuring there are the same size is a good safeguard if the goal is to copy the entire object.
assert(sizeof holding == sizeof rtp);
memcpy(holding, rtp, sizeof holding);
Use memmove() if the objects may overlap - or unsure.
This is sometimes a little slower. Usually this potential slight reduced performance is insignificant.
memmove(holding, rtp, sizeof holding);
|
Letter From A Busty Lady To Ladies With Small Boobs
There is this evil I have seen under the sun. Very nonsensical something!
.
Today I attended one of these ‘accepting yourself the way you are’ seminars. I deliberately went late. Fashionably.
.
Reason: I have accepted myself since time immemorial. I am short, fair in complexion, thick, busty and have a portable ass to complement.
When I realized my shortness, I wanted to vex for God. But then again, I discovered he gave me small sense.
Sense will do. Atleast with sense plus my other endowments, no how, I must see man. If I don’t see man, man will see me. Any way nä way.
In other words, I was not going because I needed some sort of validation, I was going because a fine boy invited me. So, Lemme just go and press phone. Before I say jack, they will close and I will see man. Finish!
The speaker was about rounding off when I strolled in.
The ushers gave me a seat very close to one guy like that. As I sank down my seat, my boobs jiggled.
“Damn!” Uncle looked at me and unconsciously exclaimed. Then my problems began.
Speaker all of a sudden, decided to talk a little more, and I became the new subject of discourse.
“Look at that girl who just walked in. Look at her big breasts! ” she shouted.
Everyone turned to peruse my innocent fun bags. Reflex action abi? Good.
” Now, a lot of flat or small chested ladies, are dying to have big boobs, not knowing that big boobs are nothing but load to the owner. They are trouble! Their owners don’t even like them. Many big breasted ladies cry in the night. You dont know! Funny enough, they don’t get married on time, because men just see them as sex tools not wife materials.
But a small or flat chested girl? No breasted distractions.So, Men hardly approach them for sex. Any man coming to them is coming for something serious like marriage. Only irresponsible men rush busty ladies. They just want to satisfy their inordinate sexual desires.” She added.
I kept screaming Waaaawu! Waawu!! Waawu! in my mind like an ambulance siren.
As I watched all the ladies with egg and lime sized boobs, applaud Aunty speaker vigorously, I looked closely at her chest. She was flat chested. Boom! There goes my answer.Smh! I smiled. She has not even accepted her self gaan, shes teaching others to. Brain dead Nigerians.
Here on Facebook, I see so many people talk down on busty ladies because they feel the urge to validate the flat chested ones. Including men.
Men who keep raping our ‘booby’ inboxes with their messages. Smh!
On many occasions also, I have noticed ladies with pimples sized boobs, make lenghty posts on how they adore their pimples. Beautiful!
But they don’t stop at telling us the advantages of their flat chests. No! They don’t stop at telling us how they can run faster than us in the event of Biafran war, because, our heavy milk industries. No! They might die as a result.
So, they go ahead to criticize we the busty ones.They tell us how we are open to cancer and they aren’t, and how our water filled heavy baloon boobs are capable of sagging early and suffocating our babies in future. Issokay.
There are many myths when it comes to large breasts. Firstly I blame society and I blame SOME flat chested girls too.
Building up another’s self worth by talking down on another is B.S. Yup! You heard me right. B.S!
Dear ‘affected’ small breasted girls,
We are not fighting with you. It is not a game of thrones sontin.We love you with the love of Christ. It is not a bad thing to be flat chested. We totally agree.
Lime sized breasts have their advantages. Great! We also agree. But can you please do your thing without making refrence to our innocent jugs? Can you stop being breast biased? Hapu nu anyi aka bikonu! We are not with your destiny.
See, downgrading our huge fun bags does not change the price of tea in China. It only makes us feel you have issues of self worth. And in the end, we don’t still hate you or our boobs.We still love you regardless, and we sympathize greatly with you.
You tell us how you can wear tanktops and denims and rock andrgynous looks like an American teenager. Agreed. We are not fighting with you. We are not dragging land.We will rock our cocktail dresses and other boobs-friendly attires in peace.
Men love you better? Great! No be fight. Carry go! We won’t even argue one bit. No strenght. We love you.
Collectively, we accept our femininity with joy. We love that natural jiggle. Nothing is better than watching a pair of breasts bounce.
Our cleavages might not be ‘office appropriate’, but we appreaciate them regardless. We know looking profesionally appropriate is difficult, no doubt.
But people like me, look forward to little accidental spill of cleavage, every now and then. I like the attention.
Yea! It makes everyone go “WHOA!” Including your fathers and boyfriends. We know. We see them.
Yes! We have a huge boobs situation. We know. But we would rather have boobs than not have boobs.
Tenkyu!
Written By Penocrat Ayomide Ugonna
#ProudlyBusty.
Signed by Eby Amanda Pius-Urum
Gen.Sec. |
Mint Spearmint
Details
Botanical Name: Menthaspicata
This is the common culinary mint which when crushed produces a long-lasting and pleasant aroma. Tiny purple flowers are borne on long spikes during late summer. Culinary: Serve with soups, sauces, in stuffings, as a traditional accompaniment to lamb and new potatoes, also good with shellfish. Crystallized leaves are an alternative decoration for cakes, cold desserts and can be used in summer drinks.
We hope you enjoy these herb seeds, just another great example of vegetable seeds from Mr Fothergill’s!
How To Grow
Sow outdoors in a well prepared seed bed in August and September. Freeze rather than dry to store. For potted plants, sow in trays of compost. Just cover the seed and keep moist. Germination may be a little erratic. Thin as necessary and transplant to their final positions in September, spacing 12in. (30cm) apart. The roots are invasive and October be contained by growing in an old bottomless bucket or between buried bricks or slate or in tubs.
When To Plant
All year round as required.
Harvest
As required
Sow
Spring, Summer, Autumn, Winter
Our Seed Guarantee
If you are not completely satisfied with these seeds Mr. Fothergill's will gladly replace them for free. Performance subject to growing conditions.
Mr. Fothergill's Seeds offers Australian gardeners the very best seed, bulb, and garden gift range in the market. Our products adhere to strict quality guidelines ensuring optimum performance and peace of mind when purchasing. |
add_llvm_library(LLVMMipsDesc
MipsABIInfo.cpp
MipsABIFlagsSection.cpp
MipsAsmBackend.cpp
MipsELFObjectWriter.cpp
MipsELFStreamer.cpp
MipsInstPrinter.cpp
MipsMCAsmInfo.cpp
MipsMCCodeEmitter.cpp
MipsMCExpr.cpp
MipsMCTargetDesc.cpp
MipsNaClELFStreamer.cpp
MipsOptionRecord.cpp
MipsTargetStreamer.cpp
)
|
<script src="{{ root_url }}/assets/bootstrap/dist/js/bootstrap.min.js"></script>
<script src="{{ root_url }}/javascripts/modernizr.js"></script>
|
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Ravensdale
Project “Ravensdale” is a fast paced fantasy action game in a very unique “steam powered” setting featuring cool and outrageously over-powered gadgetry. The player will seek out high pressure steam outlets, to supercharge his equipment, allowing him to pulverize his adversaries and overcome the obstacles on his path. |
Assessment of the decision support needs of women from HIV endemic countries regarding voluntary HIV testing in Canada.
To describe the decision support needs of immigrant and refugee women from HIV endemic countries regarding decision-making about voluntary counseling and testing for HIV (VCT) in Canada; and the needs of practitioners who support these women in making this decision, in a culturally appropriate manner. Adapted, semi-structured questionnaires, based on the Ottawa Decision Support Framework (ODSF), were used to interview practitioners and patients. Practitioners from diverse backgrounds were purposefully selected from centers providing VCT in Ottawa. Adult, English-speaking immigrant and refugee women from HIV endemic countries were recruited from a clinic specializing in immigrant health services. Responses were tabulated using descriptive statistics, and emerging themes coded to identify unique factors affecting decision-making. Analysis revealed differences between practitioner and patient perceptions of the decision-making needs of women from HIV endemic countries regarding VCT. Practitioners identified women's lack of knowledge about HIV transmission and prevention as a primary need, while patients identified inadequate awareness of HIV screening and treatment services, and their benefits and harms. Patients also perceived that women would not be aware of the various VCT options, while few practitioners highlighted this concern. Both groups held similar viewpoints about counseling strategies that could improve decision-making. Women were unaware of the options available to them for VCT. Both practitioners and patients highlighted the issue of stigma and negative outcomes associated with testing that created barriers or contributed to delays in women receiving testing. Women preferred anonymous testing, and recommended that information and decision support regarding HIV testing be provided via non-targeted strategies, and integrated within general health services or public education. Decision support in the context of VCT can improve decision quality, empowering patients to make informed decisions based on personal values. Study findings can inform the development of clinical guidelines for the routine offering of VCT. |
Q:
What is the meaning of this "go in and out"?
What is the meaning of this "go in and out": (from Randall Jarrell’s The Bat-Poet)
The chipmunk said in a pleased voice: "My day." He sat there and listened while the bat said:
In and out the bushes, up the ivy,
Into the hole
By the old oak stump, the chipmunk flashes.
Up the pole.
To the feeder full of seeds he dashes,
Stuffs his cheeks.
The chickadee and titmouse scold him.
Down he streaks.
Red as the leaves the wind blows off the maple,
Red as a fox,
Striped like a skunk, the chipmunk whistles
Past the love seat, past the mailbox,
Down the path,
Home to his warm hole stuffed with sweet
Things to eat.
Neat and slight and shining, his front feet
Curled at his breast, he sits there while the sun
Stripes the red west
With its last light: the chipmunk
Dives to his rest.
When he'd finished, the bat asked: "Do you like it?"
For a moment the chipmunk didn't say anything, then he said in a surprised, pleased voice: "Say it again." The bat said it again. When he'd finished, the chipmunk said: "Oh, it's nice. It all goes in and out, doesn't it?"
A:
I think the chipmunk is mostly referring to the rhythm of the poem - the length of each line: long, short, long, short, ..., short, long, short, long.
It certainly looks that way written down: each line alternating in and out. The chipmunk only heard it read however so it would depend on how the bat voiced it but I find myself reading it in an 'in and out' rhythm.
The motion it describes is also quite 'in and out' - the chipmunk moving hither and thither. That's especially true, of course, of the first three words.
The two combined makes it an apt and poetic description of the poem to me.
|
Q:
SPI or I2C? Termonology questions
Please help me understand why SPI and I2C SOMETIME describes SAME serial / synchronous protocol?
On Raspberry Pi the "ports" are "labeled" SDA / SCL - two wire (serial) protocol.
Please no references to "what is SPI /I2C?", just seeking clarification / comment on the above SPECIFIC question.
PS
Does "S" in SDA / SCL stands for serial or synchronous?
Given the hardware it cannot be parallel, so is "serial" redundant?
Thanks for replies.
A:
SPI and I2C are very different protocols (have a look at the Wikipedia description). They even have a different number of lines: Clock and data for I2C, and SCLK, MISO, MOSI and SS for SPI. And the pinouts for the Raspberry Pi B I've also use names like SPI_MOSI, SPI_MOSI and SPI_SCLK.
There is a protocol which is very similar (so similar it can be viewed as a kind of subset) to I2C called SMBus. Maybe you mean that instead of SPI?
That said, on embdedded SoC's like the one on the Raspberry Pi, pins of often multi-purpose, and can be reassigned to different parts of the chip (e.g. I2C controller vs. SPI controller, or even UART ...) by writing to special registers. Which is why you see particular pins used in different roles. And of course, if you use them in different, but similar roles, it makes sense to reassign them in such a way that their purpose is similar.
I've no idea if the developers of the SoC meant "serial" or "synchronous" when they named the SDA and SCL pins, and I guess it really doesn't matter ... and unless you read through the SoC documentation and get lucky and find a place where the spell out the abbreviation, it will probably remain a mystery.
|
Q:
FOSUserBundle: Get EntityManager instance overriding Form Handler
I am starting with Symfony2 and I am trying to override FOS\UserBundle\Form\Handler\RegistrationFormHandler of FOSUserBundle.
My code is:
<?php
namespace Testing\CoreBundle\Form\Handler;
use FOS\UserBundle\Model\UserInterface;
use FOS\UserBundle\Form\Handler\RegistrationFormHandler as BaseHandler;
use Testing\CoreBundle\Entity\User as UserDetails;
class RegistrationFormHandler extends BaseHandler
{
protected function onSuccess(UserInterface $user, $confirmation)
{
// I need an instance of Entity Manager but I don't know where get it!
$em = $this->container->get('doctrine')->getEntityManager();
// or something like: $em = $this->getDoctrine()->getEntityManager
$userDetails = new UserDetails;
$em->persist($userDetails);
$user->setId($userDetails->getId());
parent::onSuccess($user, $confirmation);
}
}
So, the point is that I need an instance of Doctrine's Entity Manager but I don't know where/how get it in this case!
Any idea?
Thanks in advance!
A:
You should not use EntityManager directly in most of the cases. Use a proper manager/provider service instead.
In case of FOSUserBundle service implementing UserManagerInterface is such a manager. It is accessible through fos_user.user_manager key in the service container (which is an allias to fos_user.user_manager.default). Of course registration form handler uses that service, it is accessible through userManager property.
You should not treat your domain-model (i.a. Doctrine's entities) as if it was exact representation of the database-model. This means, that you should assign objects to other objects (not their ids).
Doctrine is capable of handling nested objects within your entities (UserDetails and User objects have a direct relationship). Eventually you will have to configure cascade options for User entity.
Finally, UserDetails seems to be a mandatory dependency for each User. Therefore you should override UserManagerInterface::createUser() not the form handler - you are not dealing with user's details there anyway.
Create your own UserManagerInterface implementation:
class MyUserManager extends \FOS\UserBundle\Entity\UserManager {
/**
* {@inheritdoc}
*/
public function createUser() {
$user = parent::createUser();
$user->setUserDetails(new UserDetails());
// some optional code required for a proper
// initialization of User/UserDetails object
// that might require access to other objects
// not available inside the entity
return $user;
}
}
Register your own manager as a serive inside DIC:
<service id="my_project.user_manager" class="\MyProject\UserManager" parent="fos_user.user_manager.default" />
Configure FOSUserBundle to use your own implementation:
# /app/config/config.yml
fos_user:
...
service:
user_manager: my_project.user_manager
|
Stretching is an ancient tradition that more and more body modification fans are adopting today. Most common is the earlobe stretching, but most piercings can be stretched over time -- tongues, navels and septums. Tapers are generally used to assist in the stretching process. Tapers are needle-like tools that can be moved through your piercing at varying times to widen the hole.
A general rule with stretching is not to rush the process. You may be anxious to try out that great collection of tribal wooden body jewelry, but if you rush, you'll only end up injuring yourself. Stretch at about three times the rate as your piercing originally took to heal. For example, if your earlobe took two months to heal, wait six months to begin your stretching process with body jewelery. See your piercing professional for a steady schedule you can follow.
Ever wonder how you could make your life better and more fun? So have tens of millions of fans who have turned to LifeTips for answers over the past decade. We keep the tips, advice, books, podcasts and writing services flowing, so you can keep your life and business growing in the right direction. Upward! |
A low temperature infrared study of the coordinated water in calcium malonate dihydrate.
The infrared spectra of calcium malonate dihydrate in the polycrystalline state, both normal and with different degrees of deuteration, were obtained at low temperatures in order to obtain information about the crystalline environment of the hydration water molecules. The study showed that both water molecules are non-equivalent and non-symmetric. That result is indicative of a non-symmetric space group for the crystal, in agreement with one out of three different crystallographic studies made on the substance. |
Trackless Sea
The Trackless Sea is the name of the western ocean due west of the continent of Faerun. The Trackless Sea runs from Faerun in the west, to Maztica (where it is known as Taylola, the Eastern Ocean) and Anchorome in the east, north to to the Sea of Moving Ice and south to the peninsula of Chult. |
Ultrasonic flow meters have many advantages over other methods of determining flow rates. Ultrasonic flow meters can continuously measure the flow rate, while other methods generally measure average flow rates. In addition, ultrasonic flow meters are obstructionless and work with non-conductive fluids.
Ultrasonic flow meters have a pair of transducers that are placed on either side of the flow path of a fluid flowing through a pipe. The transducers are pointed at each other and placed on either side of the flow path of a fluid flowing through a pipe. The transducers are pointed at each other and the line between them has a component in the direction of the fluid flow. The principle used to detect flow rates is that the transit time of an ultrasonic packet will increase in the upstream and decrease in the downstream path. The amount by which the transit time changes is directly proportional to the flow rate. Generally, the signal is detected and aligned by having an oscillator that is used to trigger a transmit transducer to launch an ultrasonic packet that is received by a receive transducer. The oscillator's frequency is adjusted so that transit time is an integer multiple of the period of the oscillator signal. This allows the arrival of the ultrasonic packet to be compared with a rising edge of the oscillator signal for adjusting the oscillator signal. Flow rate determination is facilitated by having an oscillator signal with a period that is proportional to the transit time. Unfortunately, noise obscures the arrival time of the ultrasonic packet. If the noise is large enough, it completely hides the signal. This results in false and missed detections. Smaller amounts of noise cause jitter in detecting when the ultrasonic packet arrived.
Thus there exist a need for a method and apparatus that can detect an ultrasonic packet in the presence of noise. |
Common questions about the diagnosis and management of fibromyalgia.
Fibromyalgia has a distinct pathophysiology involving central amplification of peripheral sensory signals. Core symptoms are chronic widespread pain, fatigue, and sleep disturbance. Most patients with fibromyalgia have muscle pain and tenderness, forgetfulness or problems concentrating, and significant functional limitations. Fibromyalgia is diagnosed using an updated set of clinical criteria that no longer depend on tender point examination; laboratory testing may rule out other disorders that commonly present with fatigue, such as anemia and thyroid disease. Patients with fibromyalgia should be evaluated for comorbid functional pain syndromes and mood disorders. Management of fibromyalgia should include patient education, symptom relief, and regular aerobic physical activity. Serotoninnorepinephrine reuptake inhibitors, tricyclic antidepressants, antiepileptics, and muscle relaxants have the strongest evidence of benefit for improving pain, fatigue, sleep symptoms, and quality of life. Multiple complementary and alternative medicine therapies have been used but have limited evidence of effectiveness. Opioids should be used to relieve pain in carefully selected patients only if alternative therapies are ineffective. |
Visuo-perceptual organization and working memory in patients with schizophrenia.
We explore the mechanisms sub-tending the re-organization and memorization of visual information by studying how these mechanisms fail in patients with schizophrenia. Several studies have suggested that patients have difficulties in organizing information in perception and memory. We explore to what extent prompting patients to group items influences memory performance. We distinguish automatic grouping from top-down grouping processes, which are especially involved in re-organizing information. The main task was to memorize pairs of figures. Following manipulation of proximity, pairs of figures were part of the same perceptual group (within-group pair, formed on the basis of automatic grouping) or belonged to different groups (between-group pairs, re-grouped through top-down processes). Prior to the memory task, subjects ran a perception task prompting them to prioritize either within-group or between-group pairs. Unlike patients, controls globally benefited from grouping by proximity in the memory task. In addition, the results showed that prioritizing between-group pairs had a deleterious effect in patients, but with a large decrement in memory performance in the case of within-group rather than between-group figures. This occurred despite preserved focalization on within-group figures, as shown by eye-movement recordings. The suggestion is that when patients are prompted to re-group separate items, they can do so, but the benefit derived from automatic grouping is then not only lost but also reversed. This suggests re-organizing visual information not only involves re-grouping separate items but also integrating these new groups in a unified representation, which is impaired in patients with schizophrenia. |
Q:
Is there anything different between R.merge vs composing with rest operator?
Is there any advantage of use R.merge over composing with the rest operator?
const a = {name: 'john', job: 'developer'};
const b = {name: 'peter', commute: 'bike', address: {city: 'San Francisco'}};
const c = {...a, ...b};
console.log('rest', c);
const d = R.merge(a, b);
console.log('R.merge', d);
c and d appear to be the same.
Are there any cases where the rest operator won't work while R.merge will?
A:
The current implementation of R.merge is effectively R.curry((l, r) => Object.assign({}, l, r)) (albeit polyfilled when necessary), so when fully applied it will behave the same as the rest operator in your example.
The main difference being that R.merge is curried, allowing for partial application. It can also be useful when operating in environments where the rest operator (or Object.assign) isn't available.
So if you don't require partial application and have the the rest operator natively available to you, then there is little benefit to use R.merge(a, b) over {...a, ...b}.
|
Q:
how to make a form with grid view pop out with populated data, appear when a button is pressed in c#.net
I guess I need to write code in this button click event to get my desired output, but unable write down the steps. Any help from you guys would be helpful and will make me learn. Thank you.
private void btnViewAllEntries_Click(object sender, EventArgs e)
{
SqlConnection con = new SqlConnection(Helper.ConnectionString);
SqlCommand cmd = new SqlCommand("Select * from DirDetails");
con.Open();
con.Close();
MessageBox.Show(DetailsView.cs);//DetailsView.cs is winform with gridview
}
A:
First of all, MessageBox just shows messages, not Forms.
To show a Form you should instantiate it and use Show or ShowDialog methods.
DetailsView frm=new DetailsView();
frm.ShowDialog();
Second, run the query in the DetailsView.cs
private void Form1_Load(object sender, EventArgs e)
{
SqlConnection con = new SqlConnection(Helper.ConnectionString);
SqlDataAdapter da = new SqlDataAdapter("Select * from DirDetails", con);
DataTable dt = new DataTable();
con.Open();
da.Fill(dt);
con.Close();
datagridview1.DataSource = dt;
}
|
Q:
how to review a complete process/application activity?
In Ubuntu is it possible to check for an application/process activity ? I want information like
When the application/process started
what files has been accessed by the application/process
what I/O operations it have performed
If application/process connected to Internet , with what IP's its communicated.
A:
there is a tool named as Health check tool.
Health-check can monitor:
CPU utilisation
Wakeup events
Context Switches
File I/O operations (Open/Read/Write/Close using fnotify)
System calls (using ptrace)
Analysis of polling system calls
Memory utilisation (including memory growth)
Network connections
Wakelock activity
To install it open your terminal and type as
sudo add-apt-repository ppa:colin-king/white
sudo apt-get update
sudo apt-get install health-check
For information of what It can do please click here
|
@{
ViewBag.Title = "Index";
}
<h2>@ViewBag.Message</h2>
|
My GoDaddy-hosted web site won't let me configure my WOD integration
If you have a website built on the WordPress.org platform, you are able to use the Wodify-WordPress integration to send your daily WODs over to the blog page on your site. Wodify uses a plugin called 0Auth to connect to your site and posts these workouts each day.
Unfortunately, GoDaddy often applies special security settings to their WordPress-hosted pages out of the box. In order to get things working with Wodify, you'll need to reach out to them and ask them to update the .htaccess file on your web server to give Wodify permissions to post to your site via 0Auth. Follow these steps below in order to get things working! |
SUBDIRS = cli++ fdbuf mystring
noinst_LIBRARIES = libmisc.a libnullmailer.a
noinst_HEADERS = list.h
EXTRA_DIST = make_defines.sh listtest.cc mergelib.sh
CLEANFILES = defines.cc
libmisc_a_SOURCES = \
ac/dirent.h ac/time.h ac/wait.h \
address.h address.cc \
argparse.h argparse.cc \
autoclose.h \
base64.h base64.cc \
canonicalize.h canonicalize.cc \
configio.h config_path.cc \
config_read.cc config_readlist.cc config_readint.cc config_syserr.cc \
connect.h tcpconnect.cc \
defines.h \
errcodes.h errcodes.cc \
hostname.h hostname.cc \
itoa.h itoa.cc \
makefield.cc makefield.h \
netstring.h netstring.cc \
forkexec.cc forkexec.h \
selfpipe.cc selfpipe.h \
setenv.cc setenv.h
nodist_libmisc_a_SOURCES = defines.cc
libnullmailer_a_SOURCES =
libnullmailer.a: mergelib.sh libmisc.a fdbuf/libfdbuf.a \
mystring/libmystring.a Makefile
$(RM) -f libnullmailer.a
sh $(srcdir)/mergelib.sh libnullmailer.a \
libmisc.a \
fdbuf/libfdbuf.a \
mystring/libmystring.a
defines.cc: Makefile make_defines.sh
@echo Creating defines.cc
@sh $(srcdir)/make_defines.sh \
@localstatedir@/spool/nullmailer \
@sysconfdir@/nullmailer \
@libexecdir@/nullmailer \
@bindir@ \
@sbindir@
|
For a resistive random access memory (RRAM) or a phase change random access memory (PCRAM), 1T1R (i.e., a transistor and a resistive memory/a phase change memory) array architecture is a common array architecture. Comparing to the array architecture of 1T1R, 2D1R (i.e., two diodes and one resistive random access memory) can have a higher working current, a lower leakage current, and a higher array density.
In the 2D/1R array architecture, the first diode of the two diodes includes a P+ doped region and an n-well. PN junction is formed at the interface between the P+ doped region and the n-well. The second diode of the two diodes includes an N+ doped region and a p-well. PN junction is formed at the interface between the N+ doped region and a p-well. In the 2D/1R array architecture, the n-well of the first diode is used as a bit line, and the p-well of the second diode is used a reset line.
Problems arise, however, the set current and the reset current of the 2D/1R array architecture described above are small.
Therefore, there is a need to provide array architecture of a 2D/1R in which the reset current and the reset current may be increased.
The disclosed devices and methods are directed to at least partially alleviate one or more problems set forth above and to solve other problems in the art. |
KDE: Project Silk Should Integrate Web
The KDE project's Sebastian Kügler dreams of a desktop that melts, like silk, into the Web. In a writeup to KDE developers he promotes Project Silk for better Web integration.
Sebastian Kügler isn't appealing just to KDE developers involved in Web technologies, but also to application developers who want to add Web integration value to the user experience. Social desktops such as YouTube, geoweb applications and technical documents should be usable outside Web browsers, whether as wiki pages or private and confidential as webmail accounts.
Project Silk shouldn't be a mere "one-off or a single application," Kügler emphasizes. Instead, it demands participation from all KDE developers working on different programs with a single goal. Kügler assigns "silkiness" factors to applications in how close they come to Silk goals: one point for using files off the Web, one point for caching and another for clients to process Web content. Apps get another bonus point if they support multiple devices, such as a smartphone and mega-display screen.
As examples of already successful apps, Kügler cites OpenStreetMap integration in Marble, photo uploads from digiKam and web services embedded in Amarok. The trick now is to coordinate all these Web technologies among the individual apps and share code. There is already a separate Silk git repository with libraries, such as QtJson, that can serve developers. Project Silk also has its own mailing list for discussion and coordination. |
Q:
Class finalization: how to avoid creating dummy instances?
I've run into a problem that a third-party library needs to act on a class as if it was finalized. After some reading I understand the motivation behind this mechanism, but I don't really know how it functions.
Example:
(make-instance 'expression :op '+ :left 'nan :right 'nan)
(defmethod normalize-expression ((this expression))
(optima:match this
((optima::or (expression :left 'nan) (expression :right 'nan)) 'nan)
((expression :op op :left x :right y) (funcall op x y))))
Unless I add the first line, the function will not compile, giving me this error:
; caught ERROR:
; (during macroexpansion of (SB-PCL::%DEFMETHOD-EXPANDER NORMALIZE-EXPRESSION ...))
; SB-MOP:CLASS-SLOTS called on #<STANDARD-CLASS EXPRESSION>, which is not yet finalized.
; See also:
; AMOP, Generic Function SB-MOP:CLASS-SLOTS
optima is a pattern-matching library, the (expression :op op ...) is matching instances of class expression against the given pattern. I don't know in much details, but it looks like it needs to know what are the accessors defined for this class, and it looks like that information is not available until it is finalized. So, is there any way to sidestep the finalization problem?
The class will not be extended (at least not in this project, and it's not being planned). It doesn't hurt that much to create a dummy instance... it is just an ugly solution, so I hoped to find a better one. Also, perhaps, I'd get some more info on finalization, which is good too :)
A:
Forgetting to ensure class finalization seems to be quite common mistake when using MOP.
In lisp, classes are defined in two "phases":
Direct class definition
Effective class definition
Direct class definition is isomorphic to defclass form. It has class name, names of superclasses, list of direct slots (i.e., slots defined on this particular class but on its superclasses).
Effective class definition contains all information needed for compiler/interpreter. It contains list of all class slots (including those defined on superclasses), class instance layout, references to accessor methods, etc.
Process of transforming direct class definition to effective class definition is called class finalization. Since CLOS supports redefining classes, finalization might be called multiple times for a class. One of the reasons why finalization is delayed is because class may be defined before its superclasses are defined.
Regarding your particular problem: is seems that optima:match should ensure that class is finalized before trying to list its slots. This can be done with two functions: class-finalized-p (to check whether class needs finalization) and finalize-inheritance to actually perform finalization. Or you can use utility function closer-mop:ensure-finalized. (closer-mop is a library for portable usage of CLOS MOP).
E.g.,:
(c2mop:ensure-finalized (find-class 'expression))
|
What are some common causes of brown vomit?
A:
Quick Answer
Brown vomit that reeks of fecal matter may be caused by backed up bowels due to severe constipation, notes UnityPoint Health. Vomited blood may also appear brown in coloration, which is usually attributed to minor health concerns, injuries or serious ailments.
Keep Learning
Vomiting is not a disease but a manifestation of a condition, which can range from mild to more serious medical issues. The color of the vomit, which is usually indicative of the underlying cause, commonly serves as a basis for treating the condition. Individuals with bowel movement difficulty may experience abdominal bloating and severe vomiting of brown matter that smells like excrement. When this occurs, prompt medical attention is generally recommended, suggests UnityPoint Health.
There are instances when vomited blood appears brown and resembles coffee grounds, states Healthline. Non-serious conditions, such as esophageal inflammation, nosebleeds, swallowed blood or esophageal tears from persistent coughing may lead to throwing up a brown-colored vomit. Other known causes include side effects from using aspirin and non-steroidal anti-inflammatory drugs, inflammation of the stomach lining or the pancreas and presence of abdominal ulcers.
Children may also vomit blood from an accidental ingestion of a foreign object or due to a congenital abnormality. Serious medical conditions, such as cirrhosis, alcoholic hepatitis, pancreatic malignancy, erosion of the gastric lining and esophageal cancer, are also possible causes of regurgitating a bloody brownish vomitus. |
Benefits equity. Providers anticipate core mental health coverage.
In recent years, payer restrictions have led to many belt-tightening measures in the psychiatric field. But word that the administration may expand mental health insurance coverage has provided a needed shot in the arm for that field. |
Will Petreaus Call For a 'Pullback?'
The Los Angeles Times is telling us this morning that in his report to be given next month before Congress, Iraq Commander General David Petreaus will recommend a "pullback" of US forces from areas that have been sufficiently cleared of terrorists:
Intent on demonstrating progress in Iraq, the top U.S. general there is expected by Bush administration officials to recommend removing American troops soon from several areas where commanders believe security has improved, possibly including Al Anbar province.
According to the officials, Gen. David H. Petraeus is expected to propose the partial pullback in his September status report to Congress, when both the war's critics and supporters plan to reassess its course. Administration officials who support the current troop levels hope Petraeus' recommendations will persuade Congress to reject pressure for a major U.S. withdrawal.
The expected recommendation would authorize U.S. commanders to withdraw troops from places that have become less violent and turn over security responsibilities to Iraqi forces.
But it does not necessarily follow that Petraeus would call for reducing the overall number of troops in the country. Instead, he could move them to another hot spot, or use them to create a reserve force to counter any rise in violence.
That last is important to keep in mind. The troops will be redeployed to other areas where they would be needed. Certainly Petreaus has his eye on the south, especially around Basra where rival Shia militias are engaged in a low level civil war to establish their dominance in the area. Many of those militias are offshoots of radical cleric Moqtada al-Sadr's JAM force (Jaish Al Mahdi) and are hostile to Americans. Others belong to the Badr Organization who might be expected to cooperate with American forces. Establishing control in the south while breaking the power of some of the Shia militias will help bring peace to Iraq.
Will Congress buy in? Recent statements by Democratic members of Congress would seem to indicate that they may be willing to grant Petreaus more time to bring the violence in Iraq down even further. But nothing is certain at this point and both sides are on edge as the September deadline for the general's report approaches.
The Los Angeles Times is telling us this morning that in his report to be given next month before Congress, Iraq Commander General David Petreaus will recommend a "pullback" of US forces from areas that have been sufficiently cleared of terrorists:
Intent on demonstrating progress in Iraq, the top U.S. general there is expected by Bush administration officials to recommend removing American troops soon from several areas where commanders believe security has improved, possibly including Al Anbar province.
According to the officials, Gen. David H. Petraeus is expected to propose the partial pullback in his September status report to Congress, when both the war's critics and supporters plan to reassess its course. Administration officials who support the current troop levels hope Petraeus' recommendations will persuade Congress to reject pressure for a major U.S. withdrawal.
The expected recommendation would authorize U.S. commanders to withdraw troops from places that have become less violent and turn over security responsibilities to Iraqi forces.
But it does not necessarily follow that Petraeus would call for reducing the overall number of troops in the country. Instead, he could move them to another hot spot, or use them to create a reserve force to counter any rise in violence.
That last is important to keep in mind. The troops will be redeployed to other areas where they would be needed. Certainly Petreaus has his eye on the south, especially around Basra where rival Shia militias are engaged in a low level civil war to establish their dominance in the area. Many of those militias are offshoots of radical cleric Moqtada al-Sadr's JAM force (Jaish Al Mahdi) and are hostile to Americans. Others belong to the Badr Organization who might be expected to cooperate with American forces. Establishing control in the south while breaking the power of some of the Shia militias will help bring peace to Iraq.
Will Congress buy in? Recent statements by Democratic members of Congress would seem to indicate that they may be willing to grant Petreaus more time to bring the violence in Iraq down even further. But nothing is certain at this point and both sides are on edge as the September deadline for the general's report approaches. |
There are mixed messages coming from the federal government and military regarding Canadian military vets enlisting with Kurdish forces to fight against ISIS in Iraq.
On Saturday, Public Safety Minister Steven Blaney told CBC News that the government “would not oppose a citizen who is willing to engage in a battle for liberty and helping the victims of barbaric crimes,” alluding to several well-documented massacres of civilians by ISIS fighters in Iraq and Syria. Some of the killings have been videotaped and posted online to pro-ISIS YouTube accounts.
Blaney was in Halifax on Saturday attending the sixth annual International Security Forum, where the threat from ISIS and Canada’s response to it took a prominent place in discussions.
Also at that meeting was Chief of Defence Staff Tom Lawson, who wasn’t as welcoming to the idea of Canadian vets travelling overseas to join the fight against ISIS on the ground.
“I don’t encourage Canadians to leave our nation and head to other nations to get involved with the militaries of that nation,” Lawson said.
Rather, he added, vets who want to help combat ISIS should re-enlist in the Canadian Forces.
Earlier this week, CBC News reported that at least a half-dozen Canadian military veterans are currently planning on enlisting with Kurdish forces in the upcoming weeks and months. There are currently at least three Canadians purportedly fighting alongside Kurdish troops.
On Saturday, one veteran, who wished to remain anonymous, said that it was the U.S.-led coalition’s decision not to send ground troops that spurred his decision to eventually travel to northern Iraq, despite the enormous risk.
“It’s a different army and at the same time we’re going in blind. But that’s one of the risks we’re going to have to take,” he told CBC News.
It is not illegal in Canada to enlist in a foreign military force, provided it is not a group the federal government designates as a terrorist entity and it is not engaged in hostilities against Canada or its allies.
But there are several potentially complicating legal factors that could affect those who travel overseas to fight against ISIS. Some Kurdish forces themselves have been accused of war crimes, including killing prisoners and destroying villages in search of ISIS sympathizers. Kurdish officials have denied the allegations.
It emerged several weeks ago that Gill Rosenberg, a Canadian-Israeli, had become the first female foreign fighter to join the Kurds fighting ISIS. (Facebook) Similarly, Canadians travelling to Iraq and Syria could find themselves rubbing shoulders with the Kurdish PKK, a nationalist militant group in the region that fought a nearly three decade war against Turkey for independence. The Kurdish PKK is banned in Canada and the United States, where they are classified as a terrorist entity.
But the veteran who spoke with CBC News said that there are ways to ensure that his enlistment will adhere to Canadian and international law.
“You know you can’t be going around like a cowboy shooting everything. You have to be responsible, professional and follow the guidelines of the laws of war.”
Lawson acknowledged that some veterans may enlist with the Kurds even without the consent of the Canadian military, but offered up some advice to anyone considering the move.
“Be very careful. You’re swimming with the sharks and there’s no safety net, to mix analogies.” |
Academics & Research
Carl France, left, with the Alaska Center for Unmanned Aircraft Systems Integration (ACUASI) and Jimmy Fox, deputy field supervisor with the U.S. Fish and Wildlife Service, inspect an unmanned aerial vehicle used to collect video of a popular stretch of the upper Chena River which serves as prime king salmon habitat. |
The consumer market is constantly changing. Consumers are becoming more discerning and have a greater awareness of dietary needs. In particular, consumers are increasingly showing a preference for natural foods not containing any "artificial" ingredients such as preservatives, stabilisers or artificial colouring or flavouring. Fresh food is, therefore, becoming more popular than dried, processed or frozen foods.
Chilled foods are perceived as being fresh and natural, the chilled cabinet is one of the fastest growing sectors of the European food market. However, a major problem of chilled culinary foods at the present time is that, unless they contain added preservatives, the maximum shelf life is usually no more than about seven days.
When one considers that, after manufacture, the life or a chilled food usually comprises distribution to a retailer, backof-store chill storage, display in chill cabinets, purchase by the consumer, transport home and storage in the refrigerator before consumption, a shelf life of seven days is extremely short and it would be desirable to have a significantly longer shelf life of up to three weeks or more yet without the addition of any "artificial" ingredients. |
Quantitative receptor autoradiography in the human brain. Methodical aspects.
Quantitative receptor autoradiography on sections of the human brain raises methodical problems of which some are relevant also for studies in animal tissue, but others are unique in studies of human brain tissue. Procedures for the following methodical aspects are discussed: image analysis for quantitation of the regional distribution of receptor densities, saturation analysis on autoradiographs, influence of age and post-mortem delay and quenching of beta-radiation in brain tissue. The solutions proposed to these problems make receptor autoradiography in the human brain to a reliable method for studies of chemical neuroanatomy. |
I truly believe health is the real wealth. If one is healthy he/she can truly make the most of everything life has to offer. In... |
Tyler Bates Composing ‘Halloween’ Sequel
Writer/Director Rob Zombie updated his blog once again confirming the return of Tyler Bates, composer of HALLOWEEN. “Tyler Bates has returned to begin work on H2,” Zombie writes, “Fresh off his composer duties on DAY THE EARTH STOOD STILL and The WATCHMEN. The man himself will begin work immediately on the soundtrack to H2. Expect a bold new direction for the sounds to make you shiver.” Michael Myers returns to theaters August 28th from Dimension Films. |
About LSM330 Register Problem
Currently, I am now using LSM330, the only reference driver I found is official Linux-OS driver. Since there's no programming guides, I search website for source code for reference, only to find that all source code I found have a different register definition.
For instance, in a project in github, among the initialization code block, the author wrote the code below:
However, in LSM330 official datasheet, the accelerate motion sensor has no CTRL_REG1, and from the content, we can see that the author disable HPF for ACCEL, where's ACCEL-HPF??? Only gyroscope has two LPF and one HPF. |
nag – Detecting and warning about obsolete LaTeX commands
Old habits die hard. All the same, there are commands, classes and
packages which are outdated and superseded. The nag package
provides routines to warn the user about the use of such obsolete
things. As an example, we provide an extension that detects many
of the “sins” described in
l2tabu. |
Taylor Swift heads to the cinema with Loki, Thor and The Hulk!
Since they began dating a few short months ago, Taylor Swift and Tom Hiddleston have been badgered about their relationship. First Taylor was branded as ‘insensitive’ for flaunting new beau Tom while former-flame Calvin Harris had not quite recovered from their breakup, and then the A-list pair even had to respond to rumours that their relationship was a publicity stunt! No wonder Taylor and her man Tom are in need of some downtime.
With no shortage of romance between them, Taylor and Tom took their pause by heading to a cinema to watch the new ‘Ghostbusters’ movie recently. If you think that’s ordinary and not unlike your last date night, think again! For company, the couple had ‘Ghostbusters’ star Chris Hemsworth, as well as actor Mark Ruffalo. And it gets better. Not only did Tom, Taylor and their celebrity friends have the best seats in the cinema hall, they actually had the entire cinema hall to themselves. “It was Chris Hemsworth who had rented out the whole place,” a source confirmed, adding that the premium theatre also provided two wait staff, as well as food and drinks inside.
For those who want to know, the group ate popcorn and sliders while they watched Hemsworth and his co-star Melissa McCarthy on screen. Chew on that while we get over the idea of Taylor Swift watching a movie with half the ‘Avengers’ cast in attendance!
Taylor Swift heads to the cinema with Loki, Thor and The Hulk!
Since they began dating a few short months ago, Taylor Swift and Tom Hiddleston have been badgered about their relationship. First Taylor was branded as ‘insensitive’ for flaunting new beau Tom while former-flame Calvin Harris had not quite recovered from their breakup, and then the A-list pair even had to respond to rumours that their relationship was a publicity stunt! No wonder Taylor and her man Tom are in need of some downtime.
With no shortage of romance between them, Taylor and Tom took their pause by heading to a cinema to watch the new ‘Ghostbusters’ movie recently. If you think that’s ordinary and not unlike your last date night, think again! For company, the couple had ‘Ghostbusters’ star Chris Hemsworth, as well as actor Mark Ruffalo. And it gets better. Not only did Tom, Taylor and their celebrity friends have the best seats in the cinema hall, they actually had the entire cinema hall to themselves. “It was Chris Hemsworth who had rented out the whole place,” a source confirmed, adding that the premium theatre also provided two wait staff, as well as food and drinks inside.
For those who want to know, the group ate popcorn and sliders while they watched Hemsworth and his co-star Melissa McCarthy on screen. Chew on that while we get over the idea of Taylor Swift watching a movie with half the ‘Avengers’ cast in attendance! |
If Buildings could talk…
If Buildings Could Talk…
… some of them would sound like Shakespeare.
Others would speak like the Financial Times,
yet others would praise God, or Allah.
Some would just whisper,
some would loudly sing their own praises,
while others would modestly mumble a few words
and really have nothing to say.
Some are plain dead and don’t speak anymore…
Buildings are like people, in fact.
Old and young, male and female,
ugly and beautiful, fat and skinny,
ambitious and lazy, rich and poor,
clinging to the past
or reaching out to the future.
Don’t get me wrong: this is not a metaphor.
Buildings DO speak to us!
They have messages. Of course.
Some really WANT a constant dialogue with us.
Some rather listen carefully first.
And you have probably noticed:
Some of them like us a lot, some less
and some not at all.
Buildings, like people, are subject to time
and exist in a three-dimensional world.
That’s why our film is in 3D.
It’s an invitation to wander around,
to experience and to listen, for once.
The building you will encounter
is a particularly gentle and friendly one,
made for learning, reading and communicating.
Its hills and valleys (yes, they exist in there)
are eager to welcome you,
to help, to be of service,
and to be, in the best sense of the word,
a meeting place. |
Similar Products
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Answers
A:
Description:OM11083 is a Embedded Artist base board for LPCXpresso boards and embedded module. The LPCXpresso Base Board makes it possible for user to get started with experiments and prototyping immediately with the LPCXpresso Board. The LPCXpresso Base Board can also be used together with the mbed module. LPCXpresso Base Board, designed for the LPCXpresso Board (with multiple targets LPC176x, LPC1343, LPC1227, LPC11C24, LPC11U14, LPC1114 and more to come) and the mbed module from NXP. LPCXpresso is a new, low-cost development platform available from NXP. The software consists of an enhanced, Eclipse based IDE, a GNU C compiler, linker, libraries and an enhanced GDB debugger. |
Q:
dynamic publications in Meteor based on logged in user's "role"
I would like to have some publications that only return the items a user has access to based on their role. I am using the alanning:roles package to handle the roles.
For instance, I have a publication like:
Meteor.publish('header_fields', function() {
console.log("header_fields: %j", this.userId);
if (Roles.userIsInRole(this.userId,['ADMIN','INSPECTOR'])) {
// Inspectors and Admins can see all header fields
return HeaderFields.find();
} else {
// Clients should only be able to see header fields for forms they have access to
var user = Meteor.users.find({_id: this.userId});
var formIds = [];
_.each(Forms.find({client_id: user.profile.client_id}).fetch(), function(form) {
this.push(form._id);
}, formIds);
return HeaderFields.find({form_id: {$in: formIds}});
}
});
The problem I am having is that, in all the examples I have seen, publications are defined in a .js file in the server folder, and thus run and get when the client first connects. However, the user isn't logged in when the client first connects initially. But, I don't know where to put these publications or how it should work.
A:
Meteor handles this particular use-case by default in an elegant way, quoting the official docs :
this.userId
Access inside the publish function. The id of the logged-in user, or null if no user is logged in. This is constant.
However, if the logged-in user changes, the publish function is rerun
with the new value.
http://docs.meteor.com/#publish_userId
So basically it means that if you subscribed in the client to a publication which returns different documents based on this.userId as in your example, everything should work out of the box !
|
Q:
Silverlight reflection
With ASP.NET, for instance, we could reflect on the assemblies in an AppDomain, or using the type we could get the metadata about the class (props, methods, etc.). What is the technique used to extract metadata on a class, extract dependency properties, etc., in Silverlight?
A:
Reflection exists in Silverlight, with a subset of the APIs provided in the full .NET Framework.
One notable difference is that you can't reflect onto private members in Silverlight (or maybe you can inside your own assembly, but the boundaries should become apparent pretty quickly). This is a security feature to ensure you don't go messing with the internals of the framework itself.
Other than that (admittedly, rather large) limitation, Reflection should be basically the same.
A:
In addition to what Austin said, the rule with Reflection in Silverlight is that you can only access via reflection whatever you could access via normal code. So it's not just about private members. You can reflect over protected members only in the class itself or in any class inheriting it.
There are numerous missing pieces of the API but in general most things should be possible, even if they require a bit more work than in full .NET
|
Amazing how Chile looks so organized. It truly is the first south-american country to become a developed nation, regardless of any problems it might still have. Beautiful city, beautiful country, amazing skyline! |
Q:
how to use required in input
I have this input field
<td>
<input class="task-input" type="text" value="" ng-model="workflow.TaskDescription" ng-model-options="{ updateOn: 'blur' }"
ng-change="addActionButtons(workflow)" placeholder="Task" />
</td>
This field must be filled in each row and user cant fill next row while this field is empty. How to use required or ng-required in this context?
A:
use ng-required="true" inside input tag.
<td>
<input class="task-input" type="text" value="" ng-model="workflow.TaskDescription" ng-model-options="{ updateOn: 'blur' }"
ng-change="addActionButtons(workflow)" placeholder="Task" ng-required="true" />
</td>
|
Q:
Using multiple parameters in URL in express
I am using Express with Node and I have a requirement in which the user can request the URL as: http://myhost/fruit/apple/red.
Such a request will return a JSON response.
The JSON data, before the above call looks like:
{
"fruit": {
"apple": "foo"
}
}
With the above request, the response JSON data should be:
{
"apple": "foo",
"color": "red"
}
I have configured express to route as follows:
app.get('/fruit/:fruitName/:fruitColor', function(request, response) {
/*return the response JSON data as above using request.params.fruitName and
request.params.fruitColor to fetch the fruit apple and update its color to red*/
});
But this does not work. I am unsure of how to pass multiple parameters, that is, I am unsure if /fruit/:fruitName/:fruitColor is the correct way to do this. Is it?
A:
app.get('/fruit/:fruitName/:fruitColor', function(req, res) {
var data = {
"fruit": {
"apple": req.params.fruitName,
"color": req.params.fruitColor
}
};
send.json(data);
});
If that doesn't work, try using console.log(req.params) to see what it is giving you.
A:
For what you want I would've used
app.get('/fruit/:fruitName&:fruitColor', function(request, response) {
const name = request.params.fruitName
const color = request.params.fruitColor
});
or better yet
app.get('/fruit/:fruit', function(request, response) {
const fruit = request.params.fruit
console.log(fruit)
});
where fruit is a object. So in the client app you just call
https://mydomain.dm/fruit/{"name":"My fruit name", "color":"The color of the fruit"}
and as a response you should see:
// client side response
// { name: My fruit name, color:The color of the fruit}
|
Cour de Cassation — Tort Law — Damage — Legal recognised damage
The person responsible for any act which causes damage to another is bound to repair it This does not require, in the case of a fatal accident, that there be any legal relationship between the descendant and the plaintiff |
Malignant hemangioendothelioma (angiosarcoma) of the salivary gland: an ultrastructural study.
A case of malignant hemangioendothelioma (angiosarcoma) of the submaxillary salivary gland is reported and its microscopic and ultrastructural features are described and compared to previous reports of angiosarcoma arising in other locations. These tumors may often contain areas of solid sheets of cells without vascular characteristics and may be confused with poorly differentiated carcinoma or other sarcomas. The ultrastructural features of angiosarcoma are compared to other poorly differentiated tumors. It is concluded that the ultrastructural features of angiosarcoma are distinctive and aid in the diagnosis of this neoplasm. |
The Technique
We’ve all been there: Standing over a hot grill, waiting for the ribs to get tender or wondering if the chicken is cooked through (but not dried out). Brine-boiling makes grilled summer meals as easy and quick as they should be—both speeding up the cooking process and eliminating any guesswork. It even lets you prep the meat in advance.
Here’s how it works. Precook whole chicken legs, pork ribs, or beef short ribs in boiling water generously seasoned with salt, sugar, and garlic. Like a traditional brine (a mixture of salt, cold water, and sometimes seasonings in which you soak meats before cooking), this solution seasons the meat and helps keep it moist. But here you’re actually cooking the meat in the brine, which means that when you’re ready to grill, it will take mere minutes—you’re simply crisping up the exterior and layering on some smokiness. You can add a dry rub or some sauce—but the meat is great without it. And this time of year, less is more. |
[Differences in the therapeutic strategies for lung cancer between Europe/United States and Japan].
Lung cancer is a leading cause of malignancy-related death worldwide. Recently, therapeutic strategies for lung cancer have dramatically progressed, and attempts have been made to standardize the therapy for lung cancer. Because the disease prevalence and the susceptibility to the drugs differ with the circumstances, such as lifestyle, and genetic background, and ethnicity, the standard therapeutic strategies for lung cancer may differ with the individual country or region. Actually, the EGFR tyrosine kinase inhibitor, gefitinib, is well known to be significantly effective for oriental people, including Japanese, female, adenocarcinoma and never-smoker, suggesting an inherited difference. Here we describe not only the standard therapeutic strategies but also the difference in therapeutic strategies for lung cancer between Europe/United States and Japan. |
Q:
Count specific word occurrence on page
I have a webpage that has a table of usernames and scores, and it changes weekly based on scores. I just want to have a number of user's shown on my page. My table has multiple 's so using a script to count those will not work.
Every row does have something in common though, the word "Score". So I figured I could just count that word, and return the value. I cannot figure out how to just count that one word after the page is loaded completely.
Help?
Edit: fixed tag
A:
You can use simple Javascript - which is done on the clients machine, so it'll save server resources.
JSFiddle
var str = document.body.innerText;
var n = str.match(/Score/ig);
The i flag means case insensitive search
The g flag means to do a global match (match all occurrences, not just one)
|
Selectivity in DNA interstrand-stacking.
The synthesis and spectroscopic investigation of DNA hybrids containing non-nucleosidic pyrene and phenanthrene building blocks is reported. It was found that interstrand-stacking of the polyaromatic compounds in the DNA duplex takes place with a high degree of selectivity. |
The aim of the research project is a detailed understanding of the chemical reactivity of the flavin coenzymes, and how their chemical versatility is channeled and controlled in biological systems. The methods of approach will be the study of specific enzymes representative of most of the main classes of flavoproteins and studies of model systems with free flavins. Considerable use will be made of steady state kinetics coupled with rapid reaction kinetics studies, and of the technique of replacing the natural coenzymes of fiavoproteins with synthetic flavins, in order to test possible mechanisms, and to probe the nature of the environment immediately around the protein-bound flavin. This technique is not only particularly important in providing information about the active site region in proteins where structures are not available from x-ray crystallography, but in addition offers a powerful way for investigating dynamic aspects of protein structure in the case of enzymes where the crystal structure is known. We are also making extensive use of molecular genetics techniques in the elucidation of chemical reaction mechanisms. We have cloned and expressed the genes for L-lactate monooxygenase and Old Yellow Enzyme, and through our collaborators have access to genetically modified forms of L-lactate oxidase, alkyl hydroperoxide reductase and theioredoxin reductases. For all of these enzymes, three-dimensional structures are already available, or the structural determination is in progress. |
/*!
* ${copyright}
*/
sap.ui.define(["./Shape"], function (Shape) {
"use strict";
/**
*
* @constructor
*/
var Polygon = Shape.extend();
Polygon.prototype.setPosition = function (sCoords) {
this.oContainer.setAttribute("points", sCoords);
};
return Polygon;
}); |
ONE of my colleagues at the University of Virginia, a world authority on how culture influences personality, almost didn’t become a professor. He wanted to teach high school, but went for his Ph.D. because it seemed easier; he thought he would fail the exacting admissions test for teacher candidates. Perhaps I should mention that my colleague is from Japan.
When I tell this story to Americans, they usually nod knowingly, because it confirms their beliefs about the quality of teachers in both countries.
Most Americans think that teaching is a natural talent, not the product of training, and that smart people are the ones with the talent. So some policy makers have concluded that the way to improve schooling is to lure top-scoring graduates into teaching (as Japan does) instead of scraping the bottom of the academic barrel (as America supposedly does). Arne Duncan, the secretary of education, invoked this idea in a speech last year.
But the problem in American education is not dumb teachers. The problem is dumb teacher training.
It’s true that the average SAT score of high school students who plan to become teachers is below the national average. But planning to teach doesn’t guarantee that you’ll succeed in college, pass the certification test and be hired. The median SAT score for those who actually do end up teaching is about the national mean for other college graduates. (There is some variation, depending on teaching specialty.) |
//
// Author:
// Manish Sinha <manish.sinha@xamarin.com>
//
// Copyright (c) Microsoft Corporation. All rights reserved.
// Licensed under the MIT License.
using System;
using Newtonsoft.Json;
namespace Xamarin.Interactive.Representations
{
[JsonObject]
public sealed class Size
{
[JsonConstructor]
public Size (double width, double height)
{
Width = width;
Height = height;
}
public double Width { get; }
public double Height { get; }
}
} |
Mobile phone based SCADA for industrial automation.
SCADA is the acronym for "Supervisory Control And Data Acquisition." SCADA systems are widely used in industry for supervisory control and data acquisition of industrial processes. Conventional SCADA systems use PC, notebook, thin client, and PDA as a client. In this paper, a Java-enabled mobile phone has been used as a client in a sample SCADA application in order to display and supervise the position of a sample prototype crane. The paper presents an actual implementation of the on-line controlling of the prototype crane via mobile phone. The wireless communication between the mobile phone and the SCADA server is performed by means of a base station via general packet radio service (GPRS) and wireless application protocol (WAP). Test results have indicated that the mobile phone based SCADA integration using the GPRS or WAP transfer scheme could enhance the performance of the crane in a day without causing an increase in the response times of SCADA functions. The operator can visualize and modify the plant parameters using his mobile phone, without reaching the site. In this way maintenance costs are reduced and productivity is increased. |
This disclosure relates to a system and method for mass notifying recent visitors to a location.
Recently, terrorism has become a problem in many areas of the world, including on American soil. In such critical situations, communication is highly important. For this reason among others, mass notification systems have been developed and improved. However, in a facility, such as military installations, numerous individuals, uniformed or civilian individuals can enter and leave the vicinity regularly and repeatedly. As such, knowing whom to notify in a localized emergency can be difficult. Moreover, current mass notification systems are not designed for facilities comprising different visitors each day. For a military installation, particular notifications and instructions can be given to specific personnel on the base regularly, as they are known. However, visitors having minimal or irregular contact with the military installation may be difficult to contact during an emergency. Consequently, people who are not a part of the organization but none-the-less are in an area impacted by emergency may not be properly notified.
As such it would be useful to have an improved system and method for a mass notification for recent visitors to a location. |
Rat Wax™ Car Care Products are specifically designed for street rods, custom cars and motorcycles with flat, matte, satin and patina paint finishes. These products will clean, protect and maintain a matte paint finish without adding shine. The RatWax™ No Shine Car Soap cleans and protects in one easy step, while the Rat Wax™ No Shine Detailer removes dirt, dust, water spots, great, tar, fingerprints, grime, oil, & bird droppings from your car’s unique finish. The RatWax™ No Shine Detailer also leaves a clean natural look and an invisible layer of UV protection against the fade of sun, rain, and other harsh elements. Most waxes, detailers , and soaps, have either a petroleum base or gloss enhancers that contain high PH levels, which will damage these types of finishes, by changing its original sheen to a shine. Rat Wax™ also works on metal, vinyl, rubber, plastic, chrome, aluminum, and glass. |
Last one! Baymax hugging Elsa. (I think she was supposed to be sad? Again I have forgotten specifics. Apologies!) |
The one thing man cannot know is that he is at fault, that the error is not of anyone else, but only his. What is hilariously strange is, it will be blatant to every other person. The accusing finger arises from all sides of the society, but the only thing the accused knows is hostility, jealousy and that he is the victim of mean, perverse, low culture.
Introspection, self-criticism, self-awareness have thus become more and more important socially. The Bible speaks of this and any culture has a few proverbs on these values. What makes man so blind? The urge to put down the other person is greater than the aspiration to rise, as the former is easier. So he is alert in finding every defect of others, little knowing they are his own, or rather the reflection of his own.
There was a very popular man teaching in a school, popular with his students and teachers. He was the conscience keeper of his colleagues. He was a graduate in history with mathematics in his pre-degree course. So, in his teacher’s training he was trained for mathematics, which disqualified him as a permanent teacher in either subject.
Unusual circumstances combined and he landed in MA English Literature. He became very popular due to the fact that he had the uncanny faculty of knowing the other man’s sensation, which is a rare endowment in a student of literature. He was unaware of it and resented the fact when it was pointed out, due to a suspicion that he was being ridiculed. Soon his capacity was acknowledged by his classmates as well as teachers, which made him a miniature celebrity in the university. No longer did he need to return to the high school for teaching. Early in his career his services were sought after by another university from where he left for USA to do Ph.D.
What this man possessed was sense mind, which is below the Mind. In knowing that one is Spirit, not Mind, one knows the highest in oneself. A further stage is to know one’s evolving soul, the Psychic Being, to which this column pleads for attention. |
Can’t decide between minimalist and attention-seeking nails? Compromise with this split nail look. Start by taping off one half of your nail, and then paint in your basic color. Let dry and remove the tape, revealing a clean half to embellish.
Add a statement nail or two in the form of a stained glass design, either hand-painted or with the help of a nail stencil. It’s a subtle way to add personal details, seen here in the form of dainty stars of David.
This easy negative nail can be made with the help of varying nail tapes. Start with a clear base coat. Once the lacquer is tacky, set alternating strips of metallic horizontally. Seal the look with a topcoat. |
The Buzz
REVIEW: Divergent
Set in a world that is divided by the people, and supposedly, for the people. Divergent bring class warfare into the everyday. We follow a young girl named Tris Prior (Shailene Woodley) as she emerges from her upbringing to redefine herself and her way of life. Unfortunately, when she finds herself, she also discovers an anomaly that if discovered could be disastrous.
Hiding in plain sight and working to understand an emerging conspiracy are only two items on the to-do list. Tris must survive her new and violent station in life as well as her growing interest in her leader named Four (Theo James). Twists, turns and danger spill out of this movie as girl-power gets put to the test when a power struggle for the city comes to light.
A movie more interesting than the first Hunger Games, Divergent has many options for an all-out war. Meanings that are less than "hidden" and life lessons softened by love and companionship are plated in heaping portions. Aiming to be likened to many popular brands, I look forward to the opportunity of Divergent breaking ground in some way when it moves into its sequel. |
Modified asymmetric T-tube model to infer arterial wave reflection at the aortic root.
A modified version of the T-tube model was constructed to represent the systemic arterial loading system as "seen" by the left ventricle (LV). This model consisted of two uniform tubes connected in parallel. It differs from the original T-tube model in that the transmission paths have no frictional losses and are terminated with complex impedances, rather than simple resistors. To estimate model parameters (load and tube compliances, tube inertances, characteristic impedances, and peripheral resistances) we measured ascending aortic pressure and flow in a group of five open-chest, anesthetized dogs. Parameter estimates were obtained by fitting experimental pressure to the pressure predicted by the model from experimental flow. To check the reliability of the model, an additional experiment was performed where flow in the upper descending thoracic aorta was measured in addition to ascending aorta pressure and flow. The fit between the experiment and model predicted ascending aortic pressure was satisfactory in all six dogs. This pressure was always characterized by the presence of a prominent diastolic oscillation. Our model showed that this oscillation is due to reflections from the lower body, the effective reflection site being most probably located at the level of middle to low abdominal aorta. The effective reflection site located in the upper body is closer to the heart. The related reflected wave affects pressure in late systole. |
Already, the change in weather patterns, such as the ongoing impact of El-Nino has suffocated parts, if not all, the major farming areas in Fiji. As nations become more rigorous
by ranoba baoa, indonesia
FMF Foods managing director, Ram Bajekal.
Already, the change in weather patterns, such as the ongoing impact of El-Nino has suffocated parts, if not all, the major farming areas in Fiji.
As nations become more rigorous about food sovereignty, there has never been a better time for farmers in Fiji to start thinking bigger about self-sufficiency and fast.
This was the strong message by FMF Foods managing director Ram Bajekal during a big Asia Pacific conference in Bali, Indonesia this week.
“As food becomes more and more scarce, the downstream producers will need to start looking for areas where they can have long-term contracts on sourcing,” Mr Bajekal said.
“For instance, in our case, things like cassava, taro, potatoes. We will need to start looking for sources directly, in order to secure supplies that are of a continuous nature.
“And also an adequate volume that we require.”
The ‘market movers’
The meeting discussed talks about future food hikes that’s likely to be controlled by the two most powerful market movers, China and India.
“The question of how long would this threaten our food import bill, our livelihood and food security, standards of living is something that a country as small as ours should not have to endure.
“In recent times, we have seen how natural disasters have strangled our subsistence and commercial food crops.
“Already, the change in weather patterns, such as the ongoing impact of El-Nino has suffocated parts, if not all, the major farming areas in Fiji.
“Toppled by this are other areas which climate change’s impact such as coastal areas. Issues like soil inundation and soil salinity seeping through our water systems is becoming a major concern for Government and farmers.
“The question of demand and supply should now be addressed more than ever before, he added.
“There are clearly a lot of projects happening all over the place. We need a kind of focused effort into what Fiji needs,” Mr Bajekal added.
“I’m hoping that Fiji has been able to garner the kind of support that it requires from these projects.”
The workshop
The four-day conference was themed Innovation for Rural Transformation Asia and Pacific in the 21st Century.
It is focused at making global and national policies favourable to rural farmers, find marketable ways to sell their produce while at the same time overcoming issues surrounding climate change.
The meeting helped Asia Pacific government officials and executives to learn from each other’s techniques, brainstorm ideas, debate and adopt ideas that would be mutual and beneficial for their respective nations.
The drivers behind the fruitful discussions were the Indonesian government and the International Fund for Agricultural Development (IFAD).
IFAD is the United Nation’s funding institution which focuses on enabling rural people to overcome poverty, social and environmental issues like climate change.
Disintermediation
Mr Bajekal said one top priority Fiji would have to look into was disintermediation, meaning, a reduction in the use of intermediaries between producers and consumers.
“Every act of disintermediation is there is an opportunity to save some costs and that saving can be shared between the food producer and the primary producer/farmer,” he said.
“We ought to be looking backwards and try to intervene backwards with the farming sector.”
“Once there’s a linkage between the markets, the food producers and the farms there will be a huge opportunity for farmers to start looking at growing more high volume because they know that market access is short.”
The discussion was drawn from the emergence of Public-Private-Producers Partnerships or PPPP, a partnership that is for efficient and inclusive value-chain investment.
Feedback: ranobab@fijisun.com.fj |
Q:
What are the parser techniques implemented in kaitai struct? Does it implement backtracking?
I have to deal with a buffer of bytes. This buffer can have multiple grammars (A, B, C, .. , etc).
For example: AxxxxBxxxxACxxx
where x's are dirty bytes and I would like to skip them. (They don't match any grammar)
I want to know if it is possible to use kaitai-struct to parse those grammars skipping the dirty bytes.
A:
No, it's not possible, and it's generally not an objective of Kaitai Struct.
Whole idea of binary parsing is generally very different from classic parsing theory, as binary formats are designed to be machine-readable and thus are typically non-ambiguous. Binary parsers typically are very straightforward and do not employ "state", "backtracking", "recursive descent", grammars as a representation of internal state machine, etc.
|
The CRISPR-Cas system is an immune system that is found in many bacteria. It provides protection from viruses and other molecular parasites that can invade the bacterium and take over its genome. In these systems, the immunity is mediated by a complex multi-protein molecular machinery that uses RNA molecules as molecular guides to recognize the invader and target it for destruction. Until now, it has been known that the complex itself has nuclease activity -- it can directly degrade the DNA and RNA of the invading viruses. Now, an international research team headed by Martin Jinek of the University of Zurich has found a new mechanism by which the invaders get destroyed.
Signaling molecule activates additional anti-viral enzyme
The targeting machinery of CRISPR-Cas systems is composed of RNA sequences derived from clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated proteins (Cas). While the CRISPR RNAs recognize the genetic material of the invader, the Cas proteins cleave it like a molecular scissors. In a subset of CRISPR-Cas systems (known as type III), the researchers made a surprising discovery. When the targeting machinery recognizes the invader, it synthesises a "second messenger": a small, circular RNA molecule. This signaling molecule can diffuse within the bacterial cell and activates another RNA-degrading enzyme called Csm6, which then helps to destroy the RNA of the virus.
Similar mechanism as in human innate immune system
"In this way, when the CRISPR-Cas system in the infected bacterial cell becomes overwhelmed," Martin Jinek explains, "it signals an alarm by means of the second messenger to get help from another defense mechanism to eliminate the virus." In their study, the researchers were able to identify a unprecedented defense mechanism in bacteria. Moreover, second messenger molecules produced by the CRISPR-Cas system have never been observed in nature before. Furthermore, the newly found bacterial defense mechanism has some unexpected similarities to a well-known antiviral mechanism that operates in the human innate immune system. "So bacteria, in their own way, fight viral infections in a way that is surprisingly similar to what human cells do," Jinek adds. |
American Film Market kicks off next week, so be prepared for a windfall of new movies being sold to distributors. Deadline reports that a romantic comedy called Outrun has been acquired by Exclusive Media Group. Parenthood's Dax Shepard wrote and co-directed the film, which he stars in along with Kristen Bell, Bradley Cooper and Tom Arnold. David Palmer serves as co-director on the film that has Shepard playing "an ex getaway driver who breaks the rules of Witness Protection to drive his girlfriend (Bell) to Los Angeles so she can land her dream job. Authorities and his former gang (led by Cooper) get wise and try to track him down." The film was produced by Andrew Panay with Nate Tuck, Kim Waltrip and Jim Casey.
I really like Shepard and Parenthood. He and Bell have good chemistry because they are an actual couple. What are your thoughts? |
Simulations of spinodal nucleation in systems with elastic interactions.
Systems with long-range interactions quenched into a metastable state near the pseudospinodal exhibit nucleation that is qualitatively different from classical nucleation near the coexistence curve. We observe nucleation droplets in Langevin simulations of a two-dimensional model of martensitic transformations and determine that the structure of the nucleating droplet differs from the stable martensite structure. Our results, together with experimental measurements of the phonon dispersion curve, allow us to predict the nature of the droplet. The results have implications for nucleation in many solid-solid transitions and the structure of the final state. |
Hollow MnCo2O4 submicrospheres with multilevel interiors: from mesoporous spheres to yolk-in-double-shell structures.
We present a general strategy to synthesize uniform MnCo2O4 submicrospheres with various hollow structures. By using MnCo-glycolate submicrospheres as the precursor with proper manipulation of ramping rates during the heating process, we have fabricated hollow MnCo2O4 submicrospheres with multilevel interiors, including mesoporous spheres, hollow spheres, yolk-shell spheres, shell-in-shell spheres, and yolk-in-double-shell spheres. Interestingly, when tested as anode materials in lithium ion batteries, the MnCo2O4 submicrospheres with a yolk-shell structure showed the best performance among these multilevel interior structures because these structures can not only supply a high contact area but also maintain a stable structure. |
DeAndre Levy
During the season, Lions linebacker DeAndre Levy will express his thoughts in the Free Press about football and life.
I’m feeling a new energy finally getting back on the field with my teammates. It’s been a long ride but it’s been encouraging watching this defense battle and step up in crunch time. I’m getting caught up and can’t wait to be apart of this push.
The feeling of actually competing with everyone again is unrivaled. It’s especially exciting when I think about playing alongside the teammates that I’ve been lucky to have.
►DeAndre Levy:Anyone who fails to act vs. sexual abuse is ‘dirtbag’
►Related:Detroit Lions' Carey aims to help youth with new book
►Related:Lions LB DeAndre Levy expected to miss 11th straight game
I want to shout out one of those players. One who has become one of my favorite teammates I’ve ever played with: Darius (Big Play) Slay.
I don’t think there’s been a day since I’ve known him that he hasn’t been joking and laughing. I can never tell if Slay is having a bad day. He shows up, works hard and does it all with a smile. The season gets long and when I need a laugh I find Slay.
I don’t know how many times he’s had me laughing in tears at how he can beat up everybody on the team or something that he’s the best at. You name it — video games, corn hole, best hands on the team, best looking on the team, fastest, hardest hitter — Slay is always the best, according to Slay.
When he was a rookie I used to mistake his playful demeanor as him not taking his job seriously. But I was wrong.
I watch him work, from his technique on the sideline in between series during practice to working his footwork before and after. I watch how eager and fired up he gets from competing. I see the energy and focus that he uses to approach his match up each week. His unwavering confidence and joyful nature have helped him become the player he is today.
There’s no denying that Slay loves what he does and it’s important to him.
Winning makes it easier to laugh and have fun. Being on the losing end can make it easy to lose that joy. I'm glad we have a teammate like Slay, a player that always reminds you to stay loose and stay confident, win or lose. |
Q:
Change route order in Ruby on Rails
I want to have the following URL route in my application: /:username/:resource_name. So, when I type http://www.mywebsite.com/john/apple, it will load the resource called apple that belongs to john. If john or apple don't exist, it will show a message saying that the user or the resource doesn't exist.
When I create that route, it goes to the top of the routes list (rake routes). And in this way, it gets confused with other routes, such as /users/sign_in, and it says that the resource sign_in doesn't exist.
What I want to do is to send my route /:username/:resource_name right to the bottom of the routes list, so it's the last one to be matched. Is that possible, and does it solve my problem? Or is there another way to get this to work?
A:
That's very possible. The routes file is linear - routes defined first take higher precedence over the ones listed later. Just put that route at the bottom of the file.
|
package com.linbit.linstor.systemstarter;
import com.linbit.SystemServiceStartException;
import com.linbit.linstor.InitializationException;
import com.linbit.linstor.annotation.SystemContext;
import com.linbit.linstor.api.LinStorScope;
import com.linbit.linstor.core.apicallhandler.controller.CtrlSnapshotDeleteApiCallHandler;
import com.linbit.linstor.core.apicallhandler.controller.CtrlTransactionHelper;
import com.linbit.linstor.core.objects.Resource;
import com.linbit.linstor.core.objects.ResourceDefinition;
import com.linbit.linstor.core.objects.Snapshot;
import com.linbit.linstor.core.objects.SnapshotDefinition;
import com.linbit.linstor.core.repository.ResourceDefinitionRepository;
import com.linbit.linstor.dbdrivers.DatabaseException;
import com.linbit.linstor.logging.ErrorReporter;
import com.linbit.linstor.security.AccessContext;
import com.linbit.linstor.security.AccessDeniedException;
import com.linbit.linstor.tasks.RetryResourcesTask;
import com.linbit.linstor.transaction.manager.TransactionMgrGenerator;
import com.linbit.linstor.transaction.manager.TransactionMgrUtil;
import javax.inject.Inject;
import javax.inject.Singleton;
@Singleton
public class PreConnectInitializer implements StartupInitializer
{
private final ErrorReporter errorReporter;
private final ResourceDefinitionRepository rscDfnRepo;
private final CtrlTransactionHelper ctrlTransactionHelper;
private final AccessContext sysCtx;
private final LinStorScope apiCallScope;
private final TransactionMgrGenerator transactionMgrGenerator;
private final CtrlSnapshotDeleteApiCallHandler snapDelApiCallHandler;
private final RetryResourcesTask retryResourceTask;
@Inject
public PreConnectInitializer(
ErrorReporter errorReporterRef,
@SystemContext AccessContext sysCtxRef,
ResourceDefinitionRepository rscDfnRepoRef,
CtrlTransactionHelper ctrlTransactionHelperRef,
LinStorScope apiCallScopeRef,
TransactionMgrGenerator transactionMgrGeneratorRef,
CtrlSnapshotDeleteApiCallHandler snapDelApiCallHandlerRef,
RetryResourcesTask retryResourceTaskRef
)
{
errorReporter = errorReporterRef;
sysCtx = sysCtxRef;
rscDfnRepo = rscDfnRepoRef;
ctrlTransactionHelper = ctrlTransactionHelperRef;
apiCallScope = apiCallScopeRef;
transactionMgrGenerator = transactionMgrGeneratorRef;
snapDelApiCallHandler = snapDelApiCallHandlerRef;
retryResourceTask = retryResourceTaskRef;
}
@Override
public void initialize()
throws InitializationException, AccessDeniedException, DatabaseException, SystemServiceStartException
{
apiCallScope.enter();
try
{
TransactionMgrUtil.seedTransactionMgr(apiCallScope, transactionMgrGenerator.startTransaction());
for (ResourceDefinition rscDfn : rscDfnRepo.getMapForView(sysCtx).values())
{
for (SnapshotDefinition snapDfn : rscDfn.getSnapshotDfns(sysCtx))
{
if (
snapDfn.getFlags().isSomeSet(
sysCtx,
SnapshotDefinition.Flags.SHIPPING,
SnapshotDefinition.Flags.SHIPPING_CLEANUP
)
)
{
snapDfn.getFlags().enableFlags(sysCtx, SnapshotDefinition.Flags.DELETE);
for (Snapshot snap : snapDfn.getAllSnapshots(sysCtx))
{
snap.getFlags().enableFlags(sysCtx, Snapshot.Flags.DELETE);
Resource rsc = rscDfn.getResource(sysCtx, snap.getNodeName());
retryResourceTask.add(
rsc,
snapDelApiCallHandler.deleteSnapshotsOnNodes(rscDfn.getName(), snapDfn.getName())
);
}
}
}
}
ctrlTransactionHelper.commit();
}
catch (Throwable exc)
{
throw new SystemServiceStartException("Automatic injection of passphrase failed", exc, true);
}
finally
{
apiCallScope.exit();
}
}
}
|
Clostridium difficile is an emerging pathogen that causes severe and sometimes deadly colitis. Epidemiological evidence indicates that both the severity and incidence of C. difficile-associated disease (CDAD) are increasing at an alarming rate. Available treatment is inadequate and there are no licensed vaccines. Type IV pili (T4Ps), surface appendages that play important roles in infections caused by diverse bacterial pathogens, have been exploited for vaccine development. Recently, T4Ps were discovered in C. perfringens and the genes for T4Ps are present in C. difficile. Our overall hypothesis states that an immune response against the major pilin will protect against colonization and CDAD. To test this hypothesis we will first determine which pilin gene encodes the major structural subunit of the C. difficile T4P and then investigate the efficacy of immunization with purified pilin in prevention of C. difficile colonization and disease in a murine model. The proposed research is highly innovative because it will examine the potential of a novel antigen usually identified with Gram-negative bacteria to protect against colonization by a Gram-positive anaerobe. A result indicating a protective effect will have a profound effect on research and strategies for prevention and therapy for clostridial infections. The investigators have an established record of productivity studying T4P and using animal models of disease and the environment at the University of Maryland Baltimore is ideal for the proposed research. Given the indispensible role of T4Ps for other infections, the immunogenicity of pilin proteins, and the success of other T4P vaccines, we expect that a C. difficile pilin vaccine (alone or in combination with a toxoid vaccine) will generate a potent protective immune response against this potentially lethal infection. Demonstration of protection in a highly relevant animal model will pave the road to further preclinical and clinical testing. PUBLIC HEALTH RELEVANCE: Clostridium difficile is a bacterium that causes severe and sometimes deadly infections of the large intestine. Both the severity and incidence of C. difficile associated disease (CDAD) are increasing at an alarming rate. Available treatment is inadequate and there are no licensed vaccines. Type IV pili (T4Ps) are surface fibers made by many important bacteria that cause disease. T4Ps play important roles in infection and have been used successfully as vaccines. We seek to determine whether vaccination with the protein that makes up the recently discovered T4P of C. difficile will protect against colonization and CDAD. Demonstration of protection in a highly relevant animal model will pave the road to further preclinical and clinical testing and potentially lead to a new weapon to prevent this letha infection. |
Q:
Is it ok to have a collection in class ABC? Is it good practice?
I have a class suppose ABC, inside that class I have a collection of type ABC, Is it good practice, in what conditions we should try this approach?
Public Class ABC
{
Public Collection<ABC> abcCollection{get;set;}
}
A:
There are cases in which you may want to associate a class with a collection of the same class. For example::
public class Person
{
public Collection<Person> Family { get; set; }
public Collection<Person> Children { get; set; }
}
A:
You can use this approach when you want create a tree structure.For example you create a Node class and your nodes migth contain child nodes and so on like:
public class Node
{
public Node Parent { get; set; }
public ICollection<Node> Childrens { get; set; }
}
|
Q:
How to add a Defalut-welcome-intent on Dialogflow which is deleted by mistake?
I'm learning actions on google and I accidentally deleted Default-Welcome-Intent in Dialogflow. So how to add it back?
A:
Relax! There is nothing magic about the "Default Welcome Intent". In fact, you can call it anything you want. The important bit is that it have the "WELCOME" Event set. You can then add any responses you want, etc.
You can re-create it by creating a new Intent, setting the name, and setting the event. It should look something like this
|
<footer class="fn-footer" role="contentinfo">
<div class="container">
<p>This project is released for your page-designing pleasure by the Salesforce Foundation Business Applications Team under the open-source BSD license. Contributors to the project are welcome.</p>
<p><a href="http://www.getbootstrap.com">Bootstrap</a> is released under its own <a href="https://github.com/twbs/bootstrap/blob/master/LICENSE">license</a></p>
</div>
</footer> |
In a land of high rollers and risk takers, two major daily newspapers
have been playing it safe, operating under a pact that has the Las Vegas Sun running as an ad-free insert in its rival the Las Vegas Review-Journal. But after seven years under the agreement, which has maintained both news outlets as separate entities, the Sun
is shining as the brighter of the two in digital, capturing the lead in
comScore’s tally of unique visitors for the past six months. |
The only thing that stops the dust is the rain. It’s a sweet reprieve, but there is no middle ground. The land is either as dry as the Betty Ford clinic, or as wet as the ocean floor. Everything can be seen from the ridge overlooking Armadillo as John Marston gently bounces along atop...
Dont connect to someone elses connection. If you dont know the passowrd to the network - your screwed either way
-->Select Wii Options, which is located on the bottom left of the screen. This is the button with the Wii logo. Go to Wii Settings.
----> Select Internet.
----> Select Connection Settings.
-----> Choose an open connection.
-----> Choose a wireless connection.
------> Search for an Access Point, your Wii will search for a wireless network to connect to and will display a list of available networks. Networks identified with a closed padlock require authentication to join. |
comfort eating and beyond
Menu
Fun Halloween Monster Lollipops
These Monster Lollipops are so cute and such a fun project for small children to do. Perfect for Halloween and an easily adaptable idea for other festive occasions.
The lollipops are left-overs from my son’s birthday. If I didn’t already have these I probably would have used Oreo cookies as they are easily bought from the supermarket and children love them.
I bought the Wilton Candy Eyeballs from Spotlight. The multi-coloured ready-to-use fondant, sprinkles, and writing icing are available from most supermarkets. Also pictured is a small quantity of icing (powdered) sugar and some simple sugar syrup. Handy tools include a new and unused paint brush, mini-roller, skewer, small cookie cutters, and a small knife.
These are really simple to put together. Sprinkle icing sugar on the board and then roll out the fondant. Cut into shape using a knife or cookie cutters. Brush with some sugar syrup and stick on the flat side of the lollipop. Attach details and sprinkles by brushing on a little sugar syrup and gently sticking on.
Let the decorated lollipops lay flat in an air-tight container for a few days to dry. Once dry they are surprisingly sturdy. I am rather clumsy and dropped them several times when photographing them and none of the fondant pieces broke off! |
-----BEGIN RSA PRIVATE KEY-----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-----END RSA PRIVATE KEY-----
|
Antimicrobial resistance: factors and outcomes.
Antimicrobial resistance in the ICU is characterized by increasing overall resistance rates among gram-negative and gram-positive pathogens and increased frequency of multidrug-resistant organisms. In addition to basic principles of appropriate drug selection for empiric and definitive therapy, other specific strategies that may decrease problems of resistance through improved use of antimicrobials include appropriate application of pharmacokinetic and pharmacodynamic principles to antimicrobial use, aggressive dosing of antimicrobials, use of broad-spectrum and combination antimicrobial therapy for initial treatment, decreased duration of antimicrobial therapy, hospital formulary-based antimicrobial restrictions, use of antimicrobial protocols and guidelines, programs for restriction of target antimicrobials, scheduled antimicrobial rotation, and use of antimicrobial management programs. Combinations of various approaches may offer the best potential for effectively intervening in and reducing the spread of resistant pathogens in critically ill patients. |
Gerald,
Have you been able to get the Credit Ticket for the Enron North America/Upstream Master?
Have you had a chance to discuss the Master Committed Reserves contract with Jeff Hodge?
Thanks,
Judy |
Mayor Keisha Lance Bottoms issued the following statement upon the passage of legislation strengthening oversight and expanding restrictions on City credit card use.
“In keeping with our Administration’s commitment to building an ethical, transparent and fiscally responsible government, we have taken yet another significant stride towards sound stewardship of public dollars,” said Mayor Bottoms. “The legislation defines once-inexplicit guidelines, sets unequivocal expectations for card holders and outlines legal consequences—including termination of employment and criminal charges—for any violations of these new standards. I look forward to signing this new policy into law.”
Highlights of the credit card policy reform legislation include:
· Identification of City cardholders;
· Expansion of restrictions of card use—including but not limited to the purchase of alcoholic beverages, gift cards, any personal use and use of the card by anyone other than the authorized cardholder or CFO’s approved personnel;
· New definitions of legal consequences for violation or misuse of cards.
Mayor Bottoms introduced the credit card reform legislation during her first year as Mayor. |
Q:
LINQ query to select subjects of interest
Here's the query:
using (var db = CreateContext())
{
// performing the check for HasBeenAdded inline here, is this only one db call?
return db.Subjects.Select(s => new SubjectDto(s){HasBeenAdded = db.Interests.Any(x => x.SubjectId == s.SubjectId)}).ToList();
}
Basically I create a DTO from a subject and then populate a property of that DTO (HasBeenAdded) based on whether or not that entry's foreign key exists in another table. Is this the right way to go?
A:
In terms of "SQL" what you need is a "Left Outer Join". So I would suggest this:
using (var db = CreateContext())
{
var subjectDtos = from subject in Subjects
join interest in Interests on subject.SubjectId equals interest.SubjectId into si
from interest in si.DefaultIfEmpty()
select new SubjectDto { Subject = subject, HasBeenAdded = interest != null };
return subjectDtos.Distinct().ToList();
}
And here is why:
I think that LINQ query is more readable in 'SQL like' format.
With the join clause you retrieve only the "subjects" that have an "interest". But with potential duplications if more than one "interest" has the ID of the same "subject" (For this reason I introduced the "Distinct" in the query, you can remove if the duplicate results interest you).
As a matter of consistency I suggest you rather than use the constructor, initialize the property directly.
For "DefaultIfEmpty" steatment docs go here. The Left Outer Join is there.
UPDATE My first code does not work. Fixed and tested now :)
|
What's New on Jessica's Pinterest
Should I Learn to Sew?
Have you heard of a little girl named Lane Rouch? (on Instagram as ferdalump) Her sweet momma makes her BEAUTIFUL handmade Disney costumes (seriously, check her out). But even in my wildest dreams I couldn’t imagine myself making such elaborate costumes. But maybe simpler ones?
For our Year of Disney I’m picturing my little one walking around the parks in cute handmade costumes and getting tons of wonderful cast member and guest interaction. I’m sure your asking yourself, why don’t you just buy a Disney-made costume? Well, while the ones Disney makes are cute, the fabrics just don’t look very comfortable. I’m thinking a skater dress type shape made in jersey-like fabric.
The only thing holding me back is the fact that I cannot sew. At all. I asked for (and received) a sewing machine for mother’s day last year, but I haven’t even taken it out of the box. But maybe this is the kick in the pants I need? |
Not sure. Have you tried a hard reset with the pinhole button on the back? I don't know if this will leave your data intact (it should, but...), so you may want to hook it into your computer first and see about backing it up.
If this doesn't work, you might try re-flashing it again. From my studies of the upgrades that Augen provided I don't think applying multiple updates or even applying the same update twice should be any problem. Let me know how it goes.
Chris
Chris,
I am experiencing the same problem. The init screen came up and will not proceed any further. The Book cannot be powered down. I cannot connect to the computer because the device is not working properly. How do I turn this thing off? I have tried like a computer hard power down by holding the power button. NO Joy. |
if TARGET_AP_SH4A_4A
config SYS_BOARD
default "ap_sh4a_4a"
config SYS_VENDOR
default "alphaproject"
config SYS_CONFIG_NAME
default "ap_sh4a_4a"
endif
|
What basic mechanisms underlie development and how can we manipulate, disrupt, or correct them? I propose to study the collective behavior of Dictyostelium discoideum - a classic model organism for cell-cell signaling - focusing on how single-cell dynamics influence and give rise to the behavior of the aggregate. During starvation, Dictyostelium cells periodically secrete the chemoattractant cAMP, inducing production of cAMP in other cells. The result is a wavelike signal relay, and, ultimately, cellular aggregation. This transition from single-celled to multicellular life provides an ideal system to utilize my background in condensed matter physics to address a fundamental question in biology. At Princeton, I will collaborate closely with Thomas Gregor's lab, which developed the first FRET reporter of intracellular cAMP concentration. Their quantitative experiments provide a unique opportunity to connect the behavior of individual cells with the consequent fate of the population. The guidance of my mentor Ned Wingreen, an expert in bacterial chemotaxis, gradient sensing, and cell-cell communication, will be an invaluable resource. Through analysis of quantitative single-cell experiments, I have developed a model of the single-cell response to extracellular cAMP. My preliminary studies indicate that each cell behaves as an excitable system (a prime example is a spiking neuron). I will extend this model to study collective spatial dynamics mediated by diffusion of cAMP. In preliminary studies, I considered a mean-field situation, as in a well-mixed perfusion chamber, finding an intriguing dynamical quorum-sensing transition. To include spatial dynamics, I will first construct a model of spatial gradient sensing - unifying the concepts of excitability, adaptation, and directional sensing - guided by microfluidics-based experiments performed by the Gregor Lab. With this model, I will quantitatively reproduce aggregation through simulations of chemotactic cells. I will compare aggregation fidelity, measured by the size and spatial distribution of mound centers, against other chemotaxis mechanisms lacking excitable dynamics. I will then explore ways to disrupt faithful aggregation and make predictions for the behavior of various Dictyostelium mutants that can be tested in the Gregor Lab. Answering the questions in this proposal requires the right balance between using my background in condensed matter physics theory and engaging with the details of a complex biological system. The proposed project is therefore ideal for my transition to become an independent researcher working in the field of quantitative biology-it will allow me to use my established skills and to develop new ones. The environment at Princeton, both due to the guidance of my mentors, Professors Ned Wingreen and Thomas Gregor, and the greater community of quantitative biologists, provides an ideal setting to develop into an effective independent investigator. |
<!--
Please only file issues if you have confirmed the issue is valid for
the latest virt-manager code. Running code from git is pretty easy,
see CONTRIBUTING.md for details.
If you are using distro provided packages and you have not confirmed
the bug exists in this repo, then please file a bug with your distro
instead.
If you are requesting a feature or UI change, please read DESIGN.md
first, especially the section at the end about previously rejected
features.
Thank you!
-->
**Distro**: <!-- FILL ME IN PLEASE -->
|
/* ______ ___ ___
* /\ _ \ /\_ \ /\_ \
* \ \ \L\ \\//\ \ \//\ \ __ __ _ __ ___
* \ \ __ \ \ \ \ \ \ \ /'__`\ /'_ `\/\`'__\/ __`\
* \ \ \/\ \ \_\ \_ \_\ \_/\ __//\ \L\ \ \ \//\ \L\ \
* \ \_\ \_\/\____\/\____\ \____\ \____ \ \_\\ \____/
* \/_/\/_/\/____/\/____/\/____/\/___L\ \/_/ \/___/
* /\____/
* \_/__/
*
* Dynamic driver lists shared by Unixy system drivers.
*
* By Peter Wang.
*
* See readme.txt for copyright information.
*/
#include "allegro5/allegro.h"
#include "allegro5/internal/aintern.h"
#include "allegro5/internal/aintern_bitmap.h"
#include "allegro5/internal/aintern_system.h"
#if defined ALLEGRO_WITH_XWINDOWS
#ifndef ALLEGRO_RASPBERRYPI
#include "allegro5/platform/aintxglx.h"
#else
#include "allegro5/internal/aintern_raspberrypi.h"
#endif
#endif
/* This is a function each platform must define to register all available
* system drivers.
*/
void _al_register_system_interfaces(void)
{
ALLEGRO_SYSTEM_INTERFACE **add;
#if defined ALLEGRO_WITH_XWINDOWS && !defined ALLEGRO_RASPBERRYPI
add = _al_vector_alloc_back(&_al_system_interfaces);
*add = _al_system_xglx_driver();
#elif defined ALLEGRO_RASPBERRYPI
add = _al_vector_alloc_back(&_al_system_interfaces);
*add = _al_system_raspberrypi_driver();
#endif
}
|
#
# main firewall configfile.
# all settings are on sane defaults. you *really* should know what you
# do if you change them
#
# please read the readme-file or head over to:
# https://github.com/bmaeser/iptables-boilerplate
##################################################################
# IPv4 settings
##################################################################
# set to 'true' if you want to enable ipv4 forwarden
# if set to false this setting overwrites sysctl settings
ipv4_forwarding=false
# set to 'true' (default) if you want to drop and log invalid packages
drop_invalid=true
# set to 'true' (default) if you want to drop broadcast and multicast
drop_broadcast=true
# set to 'true' (default) if you want the firewall to
# detect portscans and drop+log them
drop_portscan=true
# set to 'true' (default) if you want to allow ICMP redirects only from
# our own gateway
secure_redirects=true
# set to 'true' (default) if you want to block ICMP redirects
block_redirects=true
# set to 'true' (default) if you want to ignore broadcast/multicast ICMP
# this prevents from smurf-attacks
ignore_broadcast_icmp=true
# set to 'true' (default) if you want to ignore bogues error responses
ignore_bogus_errors=true
# set to 'true' (default) if you want to block source route packages
block_source_route_packages=true
# set to 'true' (default) if you dont want to proxy arp-packages
block_proxy_arp=true
# set to 'true' (default) to enable syn-cookies.
# this prevents from syn-flood-attacks
enable_syn_cookies=true
# set to 'true' (default) to enable reverse path filter (RFC1812)
# prevents from spoofing attacks
enable_reverse_path=true
# set to 'true' (default) to disable relaying of bootp
disable_bootp_relay=true
# set to 'true' (default) to disable logging of martian packages
disable_martian_loging=true
# set to 'true' (default) to disable acceptance of source route packages
disable_srr=true
# set to 'true' (default) to enable SACK
enable_sack=true
##################################################################
### IPv6 settings
##################################################################
# set to 'true' (default) to allow ipv6 traffic on the loopback interface
ipv6_loopback_ok=true
# set to 'true' (default) to drop all other ipv6 traffic
ipv6_drop_all=true
# set to 'true' if you want to enable ipv6 forwarden
# if set to false this setting overwrites sysctl settings
ipv6_forwarding=false
# set this to 'true' if you want to disable ipv6 at all
ipv6_disabled=false
|
There are many biological methods of soil reclamation with oil pollution. Bioremediation of PAH’s-contaminated sites were largely carried out by the stimulation of microorganisms already present in the contaminated site can of difficulties with bioaugmentation processes. Successful bioaugmentation requires not only a catabolically active inoculum but also a microbial strains or consortium that can survive well in the target environment. PAH’s are often presents in a mixture of compounds in the contaminated environments, which leads to various interactions among PAH mixtures by PAH-degrading bacteria, such as cometabolism, inhibition, induction. Biodegradation by the microbial community is the primary removal mechanisms for PAHs from soil and rhizosphere and bacteria constitute the most important group of soil microbes involved in the biodegradation of PAH’s. Phytoremediation (phytoextraction, phytostabilization, phytotransformation) use of green plants to bioremediate polluted sites, was found to be a feasible approach for the in situ clean up of the soil surface contaminated with PAH’s and disel fuel. A more rapid biodegradation of PAH’s and diesel fuel in the root zone is thus important for improving phytoremediation and bioaugmentation of fuel - polluted field sites. |
package org.openstack4j.openstack.storage.block.domain;
import org.openstack4j.model.ModelEntity;
import com.fasterxml.jackson.annotation.JsonRootName;
@JsonRootName("os-force_delete")
public class ForceDeleteAction implements ModelEntity {
private static final long serialVersionUID = 1L;
public ForceDeleteAction() { }
}
|
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