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Q: Converting characters in a string swift I need to convert specific characters in a string (spaces and hyphens) to other specific characters (I will probably use an integer). I'm using a program that sends a user's location to Parse, and I need the class name to be the location, but it can't build class names with special characters or spaces. A: extension String { func exclude(excludeIt: String) -> String { return "".join(componentsSeparatedByCharactersInSet(NSCharacterSet(charactersInString: excludeIt))) } func replaceAll(find:String, with:String) -> String { return stringByReplacingOccurrencesOfString(find, withString: with, options: .LiteralSearch, range: nil) } } let helloWorld = "- -Hello - - -Wor ;ld:".exclude(" -:;") // "HelloWorld" let myReplacedString = "- -Hello - - -Wor ld".replaceAll(" ", with: "*").replaceAll("-", with: "|") // "|*|Hello*|*|*|Wor*ld"
Title A common reason that pages are not appearing in search results is the presence of the attribute rel=”nofollow” in page links. This attribute tells crawlers to not follow the link and to not record its contents. In short, if a link contains rel=”nofollow”, search cannot access it. Many link generators will include this attribute, either by default or as an option you can select. If a certain page is not showing in results for you, visit a page where it is linked to and see if rel=”nofollow” is present. If it is, edit the link and contact ucm@umn.edu to recrawl your site.
THERESA May has ordered the UK electorate to vote in exact accordance with polling numbers on 18th April, the day the election was called. Following polls showing that the Conservative lead has dropped to five points, the prime minister instructed voters to disregard every new thought they had had in the last month. She continued: “I called this election based on what you told me. If I have done that based on false pretences, I will sue. “You have no right and no business changing your views, merely because of my ‘campaign performance’. That’s nothing to do with you. “Cast your minds back to 18th April, when I announced this election and everyone agreed it would be a landslide, and bloody keep them there.” Mary Fisher of Hitchin said: “Oooh, that’s actually put me off her a little bit more. That keeps happening.”
Overview of the ability of different treatment methods for liquid and solid manure to inactivate pathogens. The use of manure as a fertilizer in agriculture includes the risk of spreading pathogenic infectious agents to the environment, to animals and humans. The treatment of manure can help avoid or reduce these risks. Even if the treatment is dominated by economic considerations such as biogas production, ammonia stripping or phosphorous precipitation, the hygienic aspect should be kept in mind. Otherwise, new infection chains may be established by the use of insufficiently treated manure by-products such as fertilizers still containing infective pathogens. Treatment plants should use a concept according to HACCP principles that includes hazard analysis, risk assessment, the determination of process relevant CCPs and the validation of the process by determining the hygienizing efficiency using representative test organisms as well as microbial end product supervision. Treatment methods can be divided into physical, chemical and microbiological treatment, sometimes used in combination. For economical reasons, only composting or anaerobic treatment (biogas) or, to a minor extent, aerobic thermophilic stabilization (ATS) are used as routine preventive measures on a farm level. In cases of outbreaks of notifiable diseases both physical and chemical treatment of manure can lead to reliable disinfected/pasteurised end products which can be used in agriculture without long-lasting risks for soil fertility or the environment.
Like millions of other Americans, I love shopping at Target. Which is why I was so appalled last week when I saw this “TROPHY” shirt proudly displayed in my local Target’s junior girls department. Calling any woman, but especially the young girls who shop in the juniors department, a “trophy” is objectifying and demeaning. We are not things - we are human beings, and we cannot let huge, influential corporations like Target get away with such irresponsible behavior. This is not the first time Target has been in hot water for sexism and gender bias, but it seems that they have not learned anything from their past mistakes. In a press release, a Target spokesperson called these shirts “a fun wink,” but I, along with thousands of other consumers, fail to see anything fun or funny about the message this shirt sends. I wish I could say that the decision to make this shirt was a simple oversight, but the truth is that dozens of people had to approve this before it hit store shelves, and that is a serious problem. The fact that no one at Target had the judgment to see this as demeaning and objectifying shows their ignorance to their own market once again. The anger is not over just one t-shirt, but the repeated (and minimized) sexism toward female consumers. You may say to yourself, "It's only a shirt, what's the big deal?" but I would respond by asking you to consider how strong words can be (especially to young people), and the power they have to both help and hinder. This shirt hinders progress made by thousands of advocates before us. It says that, despite being 'equal' on paper, we are still viewed as 'things,' and Target should not be profiting from that.
Q: PHPUnit test case aware of symfony2 dependency injection container I'm actually testing a bundle that I created. All the code is fully unit tested but now, I want to test if my symfony2 services can be request without any trouble. For that, I need the symfony2 dependency injection container in my test case. How can I do that ? A: I recently asked a question similar to this in that I needed just the validator, however the person who replied to my question first had a solution which gave access to the whole container. Basically you can pick apart WebTestCase in order to see how it builds the Symfony2 environment and make your own base class which is Symfony aware as it were. Here is the answer, I hope it helps: Symfony2: Testing entity validation constraints
Prize Summary: For the prompt: In which the real reason everything is fucked is because John is evil. We're talking pure fucking evil here, makes Jack Noir look like a girl scout, made all the more potent by the fact that John was a really nice guy up until the point where he literally tore someone into pieces. Notes: Work Text: carcinoGeneticist [CG] began trolling ectoBiologist [EB] CG: JOHN.CG: WHAT THE HELLEB: hey, karkat!CG: WHAT THE HELL DID YOU JUST DO.EB: oh, right.... i forgot about the viewport.EB: i was going to talk to you about this later!EB: i didn't really get it at first,EB: but i was thinking about what you said, and i decided that you were right!CG: WHAT THE FUCK DID I SAY.CG: WAS IT, HEY JOHN, YOU KNOW WHAT WE'VE BEEN MISSING AROUND HERE?CG: ASSHOLES LOSING THEIR SHIT AND GOING ON MURDER SPREESCG: DO YOU THINK THAT YOU CAN HELP ME WITH THIS PROBLEM.CG: OH MY GOD.EB: noooooo.....EB: it was the last conversation we had before meeting up.EB: or i guess the first one, for you.EB: about being tyrants, remember?EB: you were going to be gods, and have an entire universe as your plaything.EB: that does sound pretty sweet!CG: OH MANCG: OH GODCG: WHY IS PAST ME SUCH A GRUBFUCKING IDIOT.CG: IF I EVER MEET HIM I AM GOING TO SHOVE MY SICKLE THROUGH HIS BRAIN SPONGE.EB: karkat! i think you need to stop being so hard on yourself.EB: you're a pretty great guy!CG: NOCG: NO NO NO NOCG: I DON'T WANT TO HEAR THIS FROM YOU.EB: oh. because you still haaate me?CG: NO.CG: I MEAN YES, I HATE YOU.CG: EVERY TIME I THINK YOU ARE THE BIGGEST PIECE OF SHIT POSSIBLE,CG: IT TURNS OUT GOD TOOK ANOTHER DUMP SO BIG EVEN HE COULDN'T FLUSH ITCG: AND ADDED IT TO THE JOHN EGBERT PILECG: YOU ARE A SHIT SINGULARITY SET TO SWALLOW ALL OF PARADOX SPACECG: AND I'M TRAPPED CIRCLING THE EVENT HORIZON TO THE LOAD GAPER OF YOUR EXISTENCE.EB: ew!CG: BUT IN THIS CASE YOU NEED TO SHUT THE HELL UP BECAUSE YOU ARE SHITHIVE MAGGOTS.CG: IN RETROSPECT, YOUR WEIRD INFATUATION WITH ME TROLLING YOU SHOULD HAVE BEEN A WARNING THAT SOMETHING IS SERIOUSLY WRONG WITH YOU.CG: FUCK.EB: but i told you, bro! i'm not infatuated with you.EB: we're just buddies!CG: FUCK THAT.CG: AND FUCK YOU FOR TYPING THAT.CG: AND FUCK ME FOR NOT UNDERSTANDING THE DEFINITION OF EARTH HUMAN BUDDIES.CG: I GUESS I MISSED THE SMALL PRINT ON THE SHITTY EARTH HUMAN LABEL.CG: WARNING: HAVING EARTH HUMAN BUDDIES MAY LEAD TO YOUR OXYGEN PROCESSING SACKS EXPLODING FROM YOUR TORSO.CG: DO NOT USE IF YOU SUSPECT YOUR EARTH HUMAN BUDDY MAY FLIP OUT AND SPLATTER YOUR MUTANT COLOURED ORGAN MEATS ALL OVER THE ABANDONED LAB YOU'RE HIDING IN.EB: siiiiiigh.EB: yeah, i feel bad about how messy that was.EB: but i had to do it quick! if he escaped, it's really hard to predict what would have happened!CG: WHY WOULD YOU EVEN WANT TO KILL YOUR TIME PLAYER.CG: I DON'T GET IT.CG: PROBABLY BECAUSE I HAVEN'T GONE INSANE.CG: DID YOU THINK THE EXTRA CHANCES WOULD MAKE FACING DOWN AN OMNIPOTENT INDESTRUCTIBLE DEMON TOO BORING OR SOMETHING?EB: but we still have a time player. aradia!EB: and she's god tier- that's way higher than dave is.EB: ooops.EB: "was."EB: hehehe!CG: OH GOD OH GODEB: sorry dude. this is why i wanted to talk to you later. it's kind of hard to explain!EB: but rose figured out why we can't enter the new universe jade made.EB: it's because the game is supposed be won by a single session.EB: we have all these players with the same powers, so it doesn't know what to make of us.EB: but once we only have one of each, we should finally be able to claim our prize!EB: it's going to be great!CG: BUT WHY TIME. WE'VE GOT OTHER DUPLICATES.CG: WHY NOT START WITH THE PSYCHO LIGHT BITCHES.CG: I NOTICE ROSE IS STILL IN THE FARTHEST RING DOING HER CREEPY GOTH THING, AND VRISKACG: ...CG: JUST A MINUTECG: I NEED TOCG: ...OH FUCK. SHE'S NOT ANSWERING.EB: yeaaaaaaaahhhhhhhh........CG: OH GOD.CG: I THOUGHT YOU LIKED HER. YOU WERE THE ONLY FUCKING ONE.CG: I THOUGHT YOU WERE BUGFUCK NUTS BECAUSE YOU LIKED HER.CG: HA HA HA HA HACG: JOKE'S ON ME.CG: YOUR PRANKSTER'S GAMBIT MUST BE SHATTERING ITS METER.CG: PURPLE RECTANGLES CARVED FROM PUREST BULLSHIT FLYING EVERYWHERE.EB: hehehehe! yeah, it's pretty full right now.EB: anyway, i did like her!EB: but rose has more useful talents, even if she's not god tier.EB: we need a seer more than a thief,EB: and vriska was kind of untrustworthy, even when she tried not to be.EB: no offense!CG: WHAT THE HELL.CG: ARE YOU EVEN READING WHAT YOU'RE TYPING.CG: OR IS THAT A THING BATSHIT PSYCHO MURDERERS GET TO OPT OUT OF NOW.CG: WAIT.CG: "A SEER."CG: OH GODCG: OH MANEB: what?CG: JOHN.CG: I NEED TOCG: JUST TELL ME. ARE YOU CULLING OUR DUPLICATE CLASSES AS WELL AS ASPECTS?EB: hahaha! don't worry, bro, there's only one knight left in this game.EB: but no, rose didn't say anything about the classes.EB: i guess i will ask her later, when i tell her what i am up to!CG: OKAY.CG: THAT'S NOT ACTUALLY REASSURING.CG: BUT OKAY FOR NOW.CG: LET'S WAIT FOR ROSE TO COME BACK.CG: PRESS THE PAUSE BUTTON FOR THE KILLING RAMPAGE AND COME BACK TO IT LATER.CG: HAVE AN INTERMISSIONCG: GIVE ME A CHANCE TO USE THE LOAD GAPERCG: AND GET A GRUBSAUCE REFILLCG: AND CURL UP IN THE CORNERCG: AND FLIP THE FUCK OUT SO BADLY I CAN'T EVEN COME UP WITH A SHITTY METAPHOR FOR IT.EB: oh, yeah, i can feel that you're hyperventilating a bit.EB: here! i can help you with that!CG: NO DON'TCG: DSF;LKHASCG: ARRGHHHEB: wow, troll lungs sure are different from human ones.CG: WHAT ARE YOU DOINGCG: STOP IT STOP IT STOP IT STOP ITCG: FUCKCG: PLEASECG: STOPEB: are you feeling better yet, buddy?CG: IF I SAY YES WILL YOU STOPEB: of course! i was just getting a little concerned.EB: it would really suck if you passed out from lack of oxygen.EB: but don't worry, you've got the heir of breath looking out for you!EB: hehehehe!CG: OH GODEB: anyway, i'm about three minutes from your room, so maybe we should continue this conversation in person?CG: YOU ARE?CG: FUCK FUCK FUCK FUCK FUCKEB: well, yeah, karkat. we had plans to watch movies tonight.EB: i know you didn't forget, because you were messaging me all day about how shitty my movies always are!CG: RIGHT. UH.CG: YOU KNOW WHATCG: SOMETHING CAME UP.CG: THERE'S AN EMERGENCY.CG: TONIGHT IS REALLY BAD FOR ME AFTER ALL.CG: CAN WE CANCEL?EB: i guess...EB: i just think it would be a bad idea!EB: i brought failure to launch, with matthew mcconaughey. i think you'll like this one!EB: and we need to talk about our space player.CG: OH FUCK KANAYA AND JADE.CG: WHICH ONE DID YOUCG: FUCK I CAN'T EVEN TYPE THIS.EB: yeah, that's what we need to talk about!EB: like, jade is really smart, and she's my best friend and sort of my sister.EB: but kanaya is an alien vampire, which is totally cool, and i guess she is also sort of your girlfriend?EB: and maybe rose's as well?EB: bluh, i still don't understand how your alien romance works.CG: I DON'T GIVE A RANCID HOOFBEAST ASSFUCK ABOUT OUR ALIEN ROMANCE RIGHT NOW.CG: AND THIS IS ME YOU'RE TALKING TO,CG: SO IT MUST REALLY NOT MATTER NUBGRINDING SQUAT.EB: whatever! i'm just saying i don't know enough about kanaya.EB: but you do, and you're pretty great friends with jade too.EB: so it's probably better if you decide between them!CG: OH GODCG: I CAN'T FUCKINGCG: OH GODCG: MY BRAIN HAS JUST MELTEDCG: IT'S POOLING IN MY AURICULAR SPONGE CLOTSCG: THE ROOM IS SPINNINGCG: I GUESS BECAUSE IT'S ON THIS PIECE OF SHIT METEOR HA HA HA HAEB: um, are you alright? it feels like you're starting to hyperventilate again.CG: NO NO I'M FINE NO NO NO FUCK YOU FUCK NOEB: look, karkat, i'm not saying you need to tell me right now.EB: i know it's a big decision!EB: so we can watch failure to launch and then one of your weird troll movies that don't make any sense!EB: and we can talk about which one is better.EB: uh, out of jade and kanaya...EB: but i guess we can talk about the movies too!CG: NO. I CAN'T DO THIS.EB: sorry, but you kind of don't have a choice!CG: NO.EB: and i brought popcorn!CG: I HATE YOU.EB: suuuure you do, karkat.EB: oh man! when we get our new universe, we need to track down its version of matthew mcconaughey and enslave him!EB: force him to star in sooo many movies!EB: i can't wait!EB: this is going to be so awesome!!!
Nanowire-Coated Fabric Keeps You Warm So Your House Won’t Have To The high-tech alternative to throwing on an extra sweater
With so many countries around the world keeping a close eye on the evolution of consumer payments, drastic changes are bound to happen sooner or later. Norway is looking to get rid of cash payments altogether while the United Kingdom is being urged to embrace the blockchain and digital currency. But what would to happen if various countries around the world suddenly decided to create their own digital currency? Also read: Death of Bitcoin Network? Not so Soon! Issuing Digitized Fiat Currency On A Blockchain A few days ago, BBC mentioned how a report by the UK’s chief scientific advisor urges the government to get involved in the future development of blockchain technology. Not to aid Bitcoin directly, mind you, but rather to run the country’s public services in a more convenient, transparent, and accountable manner. It is no secret that the blockchain powering the Bitcoin network can be used for just about anything that comes to mind, even if that idea has nothing to do with finance. Data management is becoming a hot topic, as governments are collecting more information on consumers, yet fail to properly use or secure this vast wealth of information. As the name suggests, a blockchain moves blocks of data around on a network powered by computational power. Every computer dedicating its power to the blockchain network will run a perfect copy of that information, creating a completely decentralized system. By removing the central point of failure in the data storage system, there is no chance to tamper with the information recorded. Embracing the blockchain for various governmental purposes seems to be the right way forward. Not only would it be possible to store and manage data, but it would help with nearly every aspect of day-to-day actions that make a country tick. In fact, countries could even decide to digitize their local currency and issue the new form as tokens on a blockchain. This would allow for keeping tabs on local currency at any given time, and removing the threat of counterfeit money completely. While it remains unclear as to whether or not any country in the world would issue fiat currency in a digitized form on any blockchain, the concept is definitely worth considering. Such a system would run completely autonomous and removes the human element almost completely. As a result, risks of fraud and corruption are reduced to near zero, which would, in turn, be very beneficial for any economy in the world today. Norway Wants To Remove Cash Completely One of the first countries that could be looking at digitizing cash completely is Norway. Based on a recent statement by the country’s largest bank, there is no further need for cash transactions in Norway. Furthermore, cash is a dangerous and inconvenient form of payment, making it less preferable compared to electronic options. Statistics seem to indicate less Norwegians are using cash these days. Most of the payments take place with plastic cards or even mobile solutions, but there is still plenty of room for improvement, especially where card payments are concerned. The blockchain could result in faster clearing and settlement for transactions. Doing so would remove liquidity issues retailers might experience during busy sale periods or weekends, where incoming fund transfers can get delayed by several days in some cases. It would make sense for any government to embrace blockchain technology and distributed ledgers in the very near future. How this solution would be implemented, and in what capacity it would be used, is a different question, though. Digitizing existing fiat currencies is just one option, as the blockchain can be adapted to virtually suit any need that comes to mind. However, issuing independent digital currencies on a blockchain could create a whole new set of problems. Banks and governments could track all funds at any given time – including who owns it and how it is spent – which can be seen as privacy invasion. Furthermore, this would result in tons of different blockchains, which is not what the technology is about. The goal of this ecosystem is to create one platform anyone in the world can access, regardless of existing financial services or relationships with institutions. Bitcoin has shown the world how easy it is to use one blockchain connecting everybody in the world. The popular digital currency works anywhere in the world and gives the end user complete control over their finances. It remains doubtful that private blockchains – such as the ones created by banks and governments – will offer the same privileges. Source: IB Times
""" General example for an attack against code like this: Py_DECREF(obj->attr); obj->attr = ...; here in Module/_json.c:scanner_init(). Explanation: if the first Py_DECREF() calls either a __del__ or a weakref callback, it will run while the 'obj' appears to have in 'obj->attr' still the old reference to the object, but not holding the reference count any more. Status: progress has been made replacing these cases, but there is an infinite number of such cases. """ import _json, weakref class Ctx1(object): encoding = "utf8" strict = None object_hook = None object_pairs_hook = None parse_float = None parse_int = None parse_constant = None class Foo(unicode): pass def delete_me(*args): print scanner.encoding.__dict__ class Ctx2(Ctx1): @property def encoding(self): global wref f = Foo("utf8") f.abc = globals() wref = weakref.ref(f, delete_me) return f scanner = _json.make_scanner(Ctx1()) scanner.__init__(Ctx2())
Cardiotoxicities of Modern Treatments in Breast Cancer. This paper will focus on novel breast cancer therapies used in clinical practice today, as well as review our understanding of standard therapies and their potential impact on cardiovascular health. Established and novel treatments such as anthracyclines, HER2-targeted agents, and immunotherapy have contributed to improvements in breast cancer outcomes; however, these treatments may be associated with an increased risk of cardiovascular injury. The number of available breast cancer treatments continues to expand, as does the need for health care providers to understand the potential impact of these treatments on cardiovascular health. Collaborative approaches in the development of risk stratification, prevention, and surveillance strategies for patients exposed to established and novel breast cancer treatments will facilitate improvements in patient outcomes without compromising their cardiovascular health.
Q: Does the AUG | Akihabara Accept come from an anime? If so, which one? In Counter-Strike: Global Offensive a new skin was released called the Akihabara Accept. The description of the skin is: Powerful and accurate, the AUG scoped assault rifle compensates for its long reload times with low spread and a high rate of fire. It has been decorated with a heat transfer vinyl of an anime magazine cover. So I'm curious, does this actually come from a real anime magazine cover? Or is this just some custom in-house work by Valve? On the girl on the butt end of the gun the words "Fazik" are labelled on her uniform; perhaps it's part of the artist or something? Here's an imgur album with closeups of the skin in question. A: Also, as mentioned by Matt, it does not look like it comes from any specific manga or anime and is just some random Japanese anime character put on there by Steam, hoping to get some money from otaku fans alike willing to pay huge amounts of money for just an anime skin. Based on comments on it at Reddit and steam itself. If it was based on something you would expected steam to promote it as such.
import graphene from graphene import relay from ....core.permissions import ProductPermissions from ....product import models from ...core.connection import CountableDjangoObjectType from ...core.scalars import UUID from ...decorators import permission_required from ...meta.deprecated.resolvers import resolve_meta, resolve_private_meta from ...meta.types import ObjectWithMetadata class DigitalContentUrl(CountableDjangoObjectType): url = graphene.String(description="URL for digital content.") token = graphene.Field( UUID, description=("UUID of digital content."), required=True ) class Meta: model = models.DigitalContentUrl only_fields = ["content", "created", "download_num"] interfaces = (relay.Node,) @staticmethod def resolve_url(root: models.DigitalContentUrl, *_args): return root.get_absolute_url() class DigitalContent(CountableDjangoObjectType): urls = graphene.List( lambda: DigitalContentUrl, description="List of URLs for the digital variant.", ) class Meta: model = models.DigitalContent only_fields = [ "automatic_fulfillment", "content_file", "max_downloads", "product_variant", "url_valid_days", "urls", "use_default_settings", ] interfaces = (relay.Node, ObjectWithMetadata) @staticmethod def resolve_urls(root: models.DigitalContent, info, **_kwargs): return root.urls.all() @staticmethod @permission_required(ProductPermissions.MANAGE_PRODUCTS) def resolve_private_meta(root: models.DigitalContent, _info): return resolve_private_meta(root, _info) @staticmethod def resolve_meta(root: models.DigitalContent, _info): return resolve_meta(root, _info)
[Development and validation of programs for ligand-binding-pocket search]. Searching for the ligand-binding pockets of proteins plays an important role in structure-based drug design (SBDD), which is based on knowledge of the three-dimensional structures of target proteins. In SBDD, small molecules that can interact with the target protein are designed. SBDD methods require the identification of ligand-binding pockets, in which ligand molecules interact with protein atoms. The computer programs for the detection of ligand-binding pockets are categorized into two types: one is programs using only geometric properties; and the other is programs using the physicochemical properties of proteins as well as geometry. This paper describes the development and evaluation of a program for ligand-binding pocket search. The program HBOP (Hydropho Bicity On a Protein) searches for ligand-binding pockets using hydrophobic potentials derived from experimentally determined functions. This is based on the fact that hydrophobicity plays a significant role in protein-ligand binding. The results of evaluation indicate that programs using physicochemical properties can discover actual ligand-binding pockets more efficiently than those using only geometric properties.
/home/user/exo/ExoPlayer/extensions/vp9/src/main/obj/local/arm64-v8a/objs/vpx/libvpx/vpx_scale/generic/yv12extend.o: \ libvpx/vpx_scale/generic/yv12extend.c \ libvpx_android_configs/arm64-v8a/./vpx_config.h \ libvpx_android_configs/arm64-v8a/./vpx_scale_rtcd.h \ libvpx_android_configs/arm64-v8a/vpx_config.h libvpx/vpx/vpx_integer.h \ libvpx/vpx_mem/vpx_mem.h libvpx/vpx_ports/mem.h \ libvpx/vpx_scale/yv12config.h libvpx/vpx/vpx_codec.h \ libvpx/vpx/./vpx_image.h libvpx/vpx/./vpx_integer.h \ libvpx/vpx/vpx_frame_buffer.h libvpx/vp9/common/vp9_common.h \ libvpx/vpx_dsp/vpx_dsp_common.h libvpx/vpx_ports/bitops.h \ libvpx/vpx_ports/msvc.h libvpx_android_configs/arm64-v8a/./vpx_config.h: libvpx_android_configs/arm64-v8a/./vpx_scale_rtcd.h: libvpx_android_configs/arm64-v8a/vpx_config.h: libvpx/vpx/vpx_integer.h: libvpx/vpx_mem/vpx_mem.h: libvpx/vpx_ports/mem.h: libvpx/vpx_scale/yv12config.h: libvpx/vpx/vpx_codec.h: libvpx/vpx/./vpx_image.h: libvpx/vpx/./vpx_integer.h: libvpx/vpx/vpx_frame_buffer.h: libvpx/vp9/common/vp9_common.h: libvpx/vpx_dsp/vpx_dsp_common.h: libvpx/vpx_ports/bitops.h: libvpx/vpx_ports/msvc.h:
Loaded Cauliflower Mac and Cheese Paleo - Loaded Cauliflower Mac and Cheese - cauliflower tossed in a delicious paleo cheese sauce and topped with bacon. Get your mac and cheese fix without the guilt! - It’s The Best Selling Book For Getting Started With Paleo Paleo Chicken Fajita Bowl Paleo Chicken Fajita Bowl- an easy, healthy, complete meal in a bowl. Packed with juicy chicken and veggies. gluten free, and dairy free. All clean eating ingredients are used for this healthy chicken recipe. Diabetic diet foods Diabetic diet foods Paleo Takeover Infographic : Eat It, Stay Away Comments: “I do not strictly adhere to a paleo diet, but these are nice guidelines.” “Butternut squash and sweet potato are allowed” “Dairy is more of a gray area, and at any rate, grains
After six practices to open fall camp the Vols will shift gears on Tuesday for their first full-on scrimmage of August. That's always a day that comes with some anticipation -- especially for newcomers -- but it's also an important stage for the quarterbacks. That's especially true when whoever emerges as the starter under center will be a new face for Vol fans.
Pratul Sharma By Tigers are going to the dogs. An incurable pathogen named canine distemper virus, (CDV) is spreading fast from dogs to tigers, making them fearless and in the process possibly turning them into man-eaters. The most dangerous consequence of this is that the tiger population could be wiped out by the virus. The National Tiger Conservation Authority (previously called Project Tiger) has issued an advisory to all tiger range states asking them to look out for abnormal behaviour among big cats. The advisory noted the serious symptoms of CDV. “It is incurable, causing high fever, watery eyes, lethargy, vomiting and diarrhoea progressing to seizures, paralysis and death. Tigers have also been observed to display strange behaviour, with disorientation, inability to hunt, besides loss of fear.” The brain damage caused by CDV results in fatalities among tigers. However, equally disturbing are the consequences to humans. As CDV-infected tigers become fearless, they could venture into villages and towns posing a danger to humans. As shrinking habitats are forcing tigers to venture out to look for prey, cattle and stray dogs around national parks become the first victims. As many of the strays may carry CDV, it could spread to big cats, experts warn. Wildlife wardens have been asked to take precautionary measures. “Vaccination of stray cattle, cats and dogs around the tiger reserves should be done on a regular basis. Periodic checking of water quality in tiger reserves (pre and post-monsoon) along with their chemical analysis should be undertaken,” S P Yadav, Deputy Inspector General NTCA, noted. The NTCA advisory cautions wildlife authorities in different states to take notice of the dangerous phenomenon. It has asked wildlife wardens to keep an eye on wild animals showing abnormal behaviour. “Tissues of dead animals (brain tissue) should be collected for pathological analysis. Facilities of deep freezes storing samples should be set up and the record of each should be maintained.” CDV is making conservators study the phenomenon. A UK-based conservation organisation, Wildlife Vets International (WVI), involved in saving tigers in the Sunderbans — spread between Bangladesh and West Bengal — wants to test whether CDV is causing healthy tigers attack humans and walk unperturbed into villages because they have lost all fear.
Cirrhosis of the liver and receptor-mediated function in vascular smooth muscle. Altered regulation of receptors on the vascular smooth muscle has been proposed as one of the mechanisms that may account for the vascular abnormalities in patients with cirrhosis of the liver. Impaired contractility and down-regulation of contractile receptors have been demonstrated in cirrhotic patients and animal models, although interpretation of the literature is hampered by methodological variation and conflicting results. There is little evidence, however, that receptor down-regulation is the cause of contractile dysfunction in either patients or animal models. Receptor desensitisation may contribute to impaired contraction in human arteries, but further investigation is required to confirm this possibility.
var equal = require('assert').equal; var toSentence = require('../toSentence'); test('#toSentence', function() { equal(toSentence(['jQuery']), 'jQuery', 'array with a single element'); equal(toSentence(['jQuery', 'MooTools']), 'jQuery and MooTools', 'array with two elements'); equal(toSentence(['jQuery', 'MooTools', 'Prototype']), 'jQuery, MooTools and Prototype', 'array with three elements'); equal(toSentence(['jQuery', 'MooTools', 'Prototype', 'YUI']), 'jQuery, MooTools, Prototype and YUI', 'array with multiple elements'); equal(toSentence(['jQuery', 'MooTools', 'Prototype'], ',', ' or '), 'jQuery,MooTools or Prototype', 'handles custom separators'); });
GL_ARB_shader_group_vote http://www.opengl.org/registry/specs/gl/ARB/shader_group_vote.txt GL_ARB_shader_group_vote
Weaker Economy, Weaker America Martin Indyk and Michael O'Hanlon, two Democratic-leaning foreign policy scholars at the Brookings Institution, have an op-ed piece in USA Today that says America is weaker now than it was before President Obama took office: "Four straight years of trillion-dollar deficits, even if not primarily Obama's fault, leave the country weaker than when he stepped into the Oval Office," they write. Indyk served in the Clinton administration as ambassador to Israel and as assistant secretary of state.
The present disclosure relates generally to chip manufacturing, and more particularly to methods, systems and computer program products for generating functional test patterns for diagnostics, characterization and manufacture test. The generation of effective functional test patterns is a difficult and complex problem encountered at device final test. These functional test patterns need to be equivalent to system exercisers executed in a system mission mode environment. Final tests are a critical step to ensure system design verification, functionality and acceptable device quality level at system integration. The rapid densification of VLSI devices, incorporating complex functions operating at extreme circuit performance, has driven designs towards integrating many diverse functional macros or cores within these large chips. These macros range from autonomous processor cores with large cache arrays occupying relatively large portions of the chip's real estate, to a multitude of small arrays used as register stacks, trace arrays, content addressable memories, phase locked loops (PLL), and many other special purpose logic functions. These highly integrated circuit functions, in conjunction with state-of-the-art semiconductor technology advances, results in several test and diagnostic problems that have driven the generation of functional test patterns toward system equivalent functional test execution. The functional test patterns need to be used during manufacturing final tests of the device on a generic automatic test equipment (ATE) system, and these functional test patterns need to effectively emulate the execution of functional exercisers in a system mission equivalent environment. Therefore, heretofore unaddressed needs still exist in the art to address the aforementioned deficiencies and inadequacies.
Some of you may be averse to using pork rinds, but I promise you, you won't taste them in this recipe. The pork rinds mainly act as a binder for the pizza crust and there are virtually NO carbs! I will never EVER go back to regular pizza dough again! To make the pizza topping as low as possible in carbs, I made the topping as a "white" pizza - sauteed spinach, seasoned pan roasted chicken and mushrooms. This should satisfy every low-carb eater's pizza craving.
Brand Description Hunter Fleece Welly Sock Hunter sock range now has an added a new luxury material, fleece. These Hunter welly socks are the perfect companion for your Hunter boots. Warm and snug, they will keep you toasty all day no matter the weather conditions, specially designed to fit within a Hunter wellington boot with ease, say goodbye to ripping holes in your socks or wellies falling off your feet and treat your feet to some luxurious, fleece lined socks. The cuff folds over the welly, displaying the Hunter label centre front mimicking our Original boot.
package com.ruffian.widget; import android.os.Bundle; import android.support.v4.app.Fragment; import android.view.LayoutInflater; import android.view.View; import android.view.ViewGroup; /** * 示例FragmentCorner * 备注:各种圆角使用示例 * * @author ZhongDaFeng */ public class FragmentCorner extends Fragment { @Override public View onCreateView(LayoutInflater inflater, ViewGroup container, Bundle savedInstanceState) { return LayoutInflater.from(getActivity()).inflate(R.layout.fragment_corner, null); } }
Review of the state of the art in cardiovascular endoscopy imaging of atherosclerosis using photoacoustic techniques with pulsed and continuous-wave optical excitations. Intravascular photoacoustics (IV-PA) is an emerging atherosclerosis imaging modality that provides chemical-specific optical information of arterial walls with acoustic depth penetration and resolution. As lipid composition of atherosclerotic plaques is considered to be one of the primary indicators for plaque vulnerability, many IV-PA applications are calibrated so as to target plaque necrotic cores. Based on the mode of optical excitation and the corresponding signal processing technique, IV-PA is categorized into two different modalities. The pulse-based IV-PA has been the universal IV-PA imaging mode with its high peak power and straightforward time-domain signal processing technique. As an alternative, the low power continuous-wave (CW)-based IV-PA has been under intense development as a radar-like frequency-domain signal processing modality. The two state-of-the-art types of IV-PA are reviewed in terms of their physics and imaging capabilities, with major emphasis on frequency-swept CW-based IV-PA that has been recently introduced in the field.
How Well Do You Understand Design? - saurabh http://www.andyrutledge.com/design-test.php ====== herdrick Q: The most powerful and communicative shape in art and design is the: A: triangle. It's the triangle, huh? Just... the triangle. Really? Much of this quiz has the attitude of the overconfident journeyman. I'd rather listen to a master. (I'm not knowledgeable enough to criticize, but if I do maybe I'll get a little education from those here who know better. So please set me straight on triangle theory.) ~~~ george_morgan "Overconfident journeyman" sums up a lot of the web design bloggers. There is a nice quote about the difference between "men who understand everything and appreciate nothing", which seems relevant here in the sense the author appears to understand 'art' but not fully appreciate it's nuances, shown by his very rote-style. ------ aarongough And for all the understanding the author has of design, none of it stops his website feeling lopsided and cramped. I really think that interface design and user experience design are very different animals than plain 'ole graphic design. None of them are more important than the others, but they should definitely all be considered together... ~~~ SlyShy Not to mention the homepage of his website doesn't render correctly for me on Chrome with a 1024px wide screen. ~~~ jk4930 Ah, Chrome becomes the new Opera for people who love to whine around that they are an ignored minority even with using Windows while they are unable to install Linux to become a real minority. Drama queen reloaded. :) ~~~ SlyShy Cute, except that it doesn't render correctly in Firefox either. And I'm using Chrome on Linux. ;) ------ bayareaguy I find design sites like this more readable in Opera's "User Mode". ------ JohnnyBrown What is affordance? ~~~ aarongough From Wikipedia: <http://en.wikipedia.org/wiki/Affordance> It's always worthwhile doing a little research... ~~~ memetichazard The wikipedia definition is a bit abstruce. One of the links in the external links section has a much better definition, and is more relevant to usability rather than being the more general definition: <http://www.usabilityfirst.com/glossary/term_66.txl> ------ windsurfer Love how a "design" quiz requires JavaScript, but doesn't let the user know.
breastfeeding & anesthesia Your question: Can I breastfeed after my gallbladder surgery -- and will the anesthesia affect my baby? The expert answers: Breastfeeding is a good thing -- so much so, the American Academy of Pediatrics recommends an infant be given nothing else but breast milk for their entire first year of life! A breastfeeding mother may undergo surgery because of ailments that arose during pregnancy but were non-emergent. Often the surgeon will postpone surgery until after delivery -- for example excision of a lump or bump. Sometimes pregnancy can aggravate an underlying problem like gallbladder disease (cholelithiasis, cholecystitis) and the mom will need a cholecystectomy (surgical removal of gallbladder). Medications given for surgical anesthesia circulate in the bloodstream and are eliminated via the lungs (breathed out), kidneys or metabolized by the liver. The majority of medications and inhaled anesthetic agents are excreted into the milk, but in very minute quantities. Not only does the medication get diluted out in the mother's bloodstream, the amounts that are excreted into the milk are very small. Assuming a patient is able to do so, most physicians do not mind if a mother breastfeeds immediately after a surgical procedure. Remember, the mother/patient must be awake and alert enough to hold the baby. The surgical procedure determines which type of anesthesia may be used. General inhalational, regional (epidural, spinal, local anesthetics) or intravenous medications (twilight) or a combination may be given. Will the baby absorb these drugs via the breastmilk? Yes, but in relatively insignificant amounts. The amounts absorbed by the baby during breastfeeding are small compared to the blood levels reached when a baby receives anesthesia for a surgical procedure on itself. The circumstances surrounding each surgery and anesthetic can vary, so plan to ask your physician about breastfeeding during your pre-op visit.
<?php namespace TRegx\CleanRegex\Match; use TRegx\CleanRegex\Internal\Match\Base\FilteredBaseDecorator; use function count; class FilteredMatchPattern extends AbstractMatchPattern { public function __construct(FilteredBaseDecorator $base) { parent::__construct($base); } public function test(): bool { return !empty($this->getMatchObjects()); } public function count(): int { return count($this->getMatchObjects()); } }
The RCMP is refusing to pay the medical bills for Mounties treated by an outspoken critic of the force, CBC News has learned Patients of B.C. psychologist Mike Webster have been told to find another doctor, or pay for Webster's sessions out of their own pocket. Webster treats about two dozen RCMP officers who are on medical leave due to some sort of on-the-job conflict. Webster said the RCMP's move to silence him is a political vendetta that will only hurt its own members. "It just amazes me that one little-old-psychologist can have this kind of effect on the RCMP— can bring it to its knees so that they have to resort to something like this," Webster said. In a letter sent to Webster, the RCMP said its medical case managers lodged the complaint because: ...your lack of objectivity in both your clinical work and public commentary towards the RCMP have weakened your effectiveness in treating your RCMP client base. (CBC) The RCMP also lodged a formal complaint against Webster with the College of Psychologists of British Columbia. In a letter sent to Webster, the RCMP said its medical case managers lodged the complaint because: "...your lack of objectivity in both your clinical work and public commentary towards the RCMP have weakened your effectiveness in treating your RCMP client base." It also said it is concerned Webster isn't getting his patients back to work quickly enough. Webster has long argued that an unhealthy workplace can affect a person's mental health, but he said the RCMP doesn't want to fix that. He said the force just wants its members work-ready. "It's uncontroversial that working for the RCMP can make you sick, so why would I want to return my patients to the toxic environment that made them sick in the first place?" Cpl. Roland Beaulieu has been off work since February of last year due to what he described as systemic harassment issues. He said he's been seeing Webster for about two years, and has improved. He said it should be up to him who he sees — not the RCMP. Cpl. Roland Beaulieu said it should be up to him to choose a psychologist, not the RCMP. (CBC) "For them to dictate who I see tells me they want a certain report back that they're happy, not necessarily the truth," he said. "And sometimes the truth hurts." The RCMP said members can still see Webster: It just won't pay for it. Supt. Kevin DeBruyckere said the change is not meant to be punitive and that with Webster's co-operation, patients can transition to other psychologists. "The number one priority is the health of the members. A by-product of that is getting them back to work. And that's the expectation of our employees, of those members and of the people who are paying for it: the taxpayers," DeBruyckere said. Cpl. Beaulieu said the organization is making Webster's patients suffer. He said if the RCMP really cared about the health of its members, it would put its differences with Webster aside.
Stable albinism induced without mutagenesis: a model for ribosome-free plastid inheritance. Maternally inherited chlorophyll deficiency, or albinism, is a standard marker in plant cytoplasmic genetics. Its stability is consistent with mutations in the plastid genome. Nuclear mutations inducing plastid ribosome deficiency (PRD) also lead to maternally inherited chlorophyll deficiency. Here we report that stable chlorophyll deficiency can be efficiently generated in cruciferous plants without mutagenesis by a short exposure to spectinomycin, an inhibitor of plastid protein synthesis. We show that the chlorophyll-deficient phenotype results from a deficiency in plastid ribosomes and plastid translation products. Loss of plastid ribosomes is irreversible. The data suggest that mutations are not essential for generating inheritable PRD. It allows the formulation of a more general model in which stable PRD can be induced by a variety of factors that prevent the formation of functional plastid ribosomes. A non-mutational mechanisms for generating inheritable chlorophyll deficiency has implications for the origin and inheritance of green-white variegation in nature.
The first step to building an amazing About page is to figure out what you want the page to say about your company. You then must grab the attention of the reader, boast a bit, tell a story and let others brag about you. With a little bit of thought… In this Micro Tutorial viewers will learn how to create navigation buttons that change on rollover, using CSS (Continuation of the CSS Image Sprite tutorial) Create a parent ID for all the list items - Specify position: absolute and display: block… In this tutorial viewers will learn how to style a corner ribbon overlay for an image using CSS Create a new class by typing ".Ribbon": Define the class' "display:" as "inline-block": Define its "position:" as "relative": Define its "overflow:" as …
How to speed up timers? Hello everyone! Simply my question is how to speed up timers in Adobe AIR/Actionscript. I recently have encountered a timer on a game and I just want to speed it up. I just am not familiar with flash coding as I have only used C++ and Java but still.... I have seen people doing this through a an executable program that would speed the timer up as the process was running which I thought was ingenious. Now I just want to replicate that with your help! Anything will help me as at this moment I am doing a lot of research as well.
Red blood cell polyamines in mice bearing the Lewis lung carcinoma (3LL) and in patients with bronchopulmonary cancers. Experimentally, during Lewis lung carcinoma (3LL) growth, the red blood cell (RBC) polyamine levels increase with tumor volume and are inversely correlated to tumoral concentrations of spermidine and spermine. The RBC level of spermidine is continually correlated to both the volume and the tumoral concentration of this polyamine. Clinically, high levels of RBC polyamine are observed in cases of squamous-cell carcinoma or anaplastic cancer, and not in cases of adenocarcinoma. RBC polyamine levels only permit the establishment of statistical differences between groups of patients. Therefore, clinical use of these molecules as tumor markers depends on an understanding of polyamine distribution within blood.
// Ionic Starter App // angular.module is a global place for creating, registering and retrieving Angular modules // 'starter' is the name of this angular module example (also set in a <body> attribute in index.html) // the 2nd parameter is an array of 'requires' // 'starter.controllers' is found in controllers.js angular.module('starter', ['ionic', 'starter.controllers']) .run(function($ionicPlatform) { $ionicPlatform.ready(function() { // Hide the accessory bar by default (remove this to show the accessory bar above the keyboard // for form inputs) if(window.cordova && window.cordova.plugins.Keyboard) { cordova.plugins.Keyboard.hideKeyboardAccessoryBar(true); } if(window.StatusBar) { // org.apache.cordova.statusbar required StatusBar.styleDefault(); } }); }) .config(function($stateProvider, $urlRouterProvider) { $stateProvider .state('app', { url: "/app", abstract: true, templateUrl: "templates/menu.html", controller: 'AppCtrl' }) .state('app.search', { url: "/search", views: { 'menuContent' :{ templateUrl: "templates/search.html" } } }) .state('app.browse', { url: "/browse", views: { 'menuContent' :{ templateUrl: "templates/browse.html" } } }) .state('app.playlists', { url: "/playlists", views: { 'menuContent' :{ templateUrl: "templates/playlists.html", controller: 'PlaylistsCtrl' } } }) .state('app.single', { url: "/playlists/:playlistId", views: { 'menuContent' :{ templateUrl: "templates/playlist.html", controller: 'PlaylistCtrl' } } }); // if none of the above states are matched, use this as the fallback $urlRouterProvider.otherwise('/app/playlists'); });
All Titles in PHP PHP is still today's most popular open source web scripting language for web application developers. Apress is a leading publisher of PHP books including best sellers starting with Jason Gilmore's Beginning PHP and MySQL, David Power's PHP Solutions and much more.
#if !NETSTANDARD2_0 // Copyright (c) Microsoft Open Technologies, Inc. All rights reserved. See License.txt in the project root for license information. namespace ServiceStack.Html.AntiXsrf { // Abstracts out the serialization process for an anti-forgery token internal interface IAntiForgeryTokenSerializer { AntiForgeryToken Deserialize(string serializedToken); string Serialize(AntiForgeryToken token); } } #endif
After the build has completed and the container is pushed to docker hub, you can deploy the app into your cluster. Ensure that the container image value in service.yaml matches the container you built in the previous step. Apply the configuration using kubectl: kubectl apply --filename service.yaml Now that your service is created, Knative performs the following steps: Automatically scale your pods up and down (including to zero active pods). Run the following command to find the external IP address for your service. The ingress IP for your cluster is returned. If you just created your cluster, you might need to wait and rerun the command until your service gets asssigned an external IP address.
Q: How to send json response in redirect url for jquery file upload I am using blueimp file upload and on server side i am using cgi script.I am able to upload the file and getting valid json data.Now what i want is to sent this json data to the redirect url so i can do further procession on the redirect page. My js code in jsp page is as follows:- $(function () { //alert(window.location.hostname); 'use strict'; var urlTemp = '<%=actionStr%>'; var successurl = '<%=successURL%>'; $('#fileupload').fileupload( { url: urlTemp, sequentialUploads: true, redirect: successurl, type: 'POST' } ); $('#fileupload').bind('fileuploadstop', function (e, data) { data.formdata = data.result; alert(data); alert(data.formdata); //getting undefined window.location.href = successurl; } ); $('#fileupload').fileupload('option','url'); }); in fileuploadstop event i am getting data.result as 'undefined'. A: Try doing it like this: $('#fileupload').bind('fileuploaddone', function (e, data) { var results = data.result; });
House Intel Chair: Snowden Is Lying About Access To Surveillance Program The chairman of the House Intelligence Committee said Thursday that the man who leaked information about National Security Agency surveillance programs is lying about his access to that information as well as the programs' scope. "He was lying," Rep. Mike Rogers (R-MI) said after a closed briefing with NSA Director Keith Alexander, as quoted by The Hill. "He clearly has over-inflated his position, he has over-inflated his access and he's even over-inflated what the actually technology of the programs would allow one to do. It's impossible for him to do what he was saying he could do." Leaker Edward Snowden claimed that while working for a security contractor, he had virtually unlimited access to the information the NSA's phone and internet data collection programs culled. "The NSA has built an infrastructure that allows it to intercept almost everything," Snowden told The Guardian. "If I wanted to see your emails or your wife's phone, all I have to do is use intercepts. I can get your emails, passwords, phone records, credit cards."
Contents History Mr. Zimmwad used to be a dead spider, who Sir Pickles found the dead spider and built a body for, creating Mr. Zimmwad. At some point in Dark's first movie, he was cloned millions of times, resulting in the original dying. All of the clones were programmed to destroy Dark709. After the movie, all but ten of the Zimmwad Clones were destroyed, these clones having been manufactured independently from the other clones. Mr. Zimmwad took command of them, but after the third season, they were killed. Controversy Interestingly, the first form of Mr. Zimmwad seems to be a direct copy of Doom from Marty Razor Kirra's The Doom Chronicles. Apparently, at the time, Dark709 did not like recoloring (which is why why Sir Pickles was the default Razor palette before getting switched to blue/Dark709 in Razor was the Matoran Makuta sprite), and thought that the character looked good, so he used it.
Q: php class extends - attributes/methods with same name ok? If you have a class named "User" and another class named "Admin" that extends "User", and you want Admin to inherit all attributes,methods from User, except for the __construct method, for example. class User { private $name; function __construct($name) { $this->name = $name; } } and class Admin extends User { private $authorization; function __construct($name,$authorization) { $this->name = $name; $this->authorization = $authorization; } } Is this correct? Does Admin override User's construct method? If the extending class has the same method name I suppose it's invalid. Am I totally missing the point of class extension? A: It is not invalid. One aspect of class inheritance is, that you can override methods and provide another implementation. But in your case, I would do class Admin extends User { private $authorization; function __construct($name,$authorization) { parent::__construct($name); $this->authorization = $authorization; } } as you already implement the "name assignment" in the parent class. It is a cleaner approach.
Q: Ruby gem to quickly validate partial HTML snippets? I'm making a customized quasi-CMS in Rails, and we'd like to have one field that is editable as an HTML fragment in code (the admin interface will be using CodeMirror on the frontend). When it's presented to the end user, it will just be html_safe'd and inserted into a div. We trust our content editors not to be malicious, but it would be helpful to ensure they're creating valid HTML so they don't break the page, especially since they're relatively new to coding! As a first attempt, I'm using Hash.from_xml and rescuing exceptions as a custom validator. But is there a better and/or more-optimized way (i.e. a gem) to check that it is valid HTML? Thanks! A: You can use the Nokogiri library (and gem) to create a validator in your model. Using Nokogiri on fragments isn't perfect (so you might want to add the ability to override the validator) but it will catch many obvious errors that might break the page. Example (assuming your model attribute/field is called content): validate :invalid_html? def invalid_html? doc = Nokogiri::HTML(self.content) do |config| config.strict end if doc.errors.any? errors.add(:base, "Custom Error Message") end end A: Instead of validation, perhaps it's worth to use Nokogiri which is capable of fixing markup: require 'nokogiri' html = '<div><b>Whoa</i>' Nokogiri::HTML::DocumentFragment.parse(html).to_html #=> "<div><b>Whoa</b></div>"
Influence of hepatitis B virus genotypes on the response to antiviral therapies. Hepatitis B virus (HBV) has been classified into eight genotypes (A-H) based on genome sequence divergence. Genotypes of HBV have distinct geographical distributions, and two genotypes account for most HBV worldwide. Hepatitis B e antigen expression lasts longer and liver disease is more severe with graver outcomes in carriers of genotype C than B in Asia. Accumulating lines of evidence indicate a better response to interferon and lamivudine in patients with chronic hepatitis B who are infected with genotype B rather than C. The therapeutic response may differ, however, in patients infected with HBV of the same genotype. For example, the response to lamivudine is poorer in patients infected with subtype Ba, which contains a recombination with genotype C, than in those with subtype Bj without such a recombination. Influence of genotypes on therapeutic response needs to be examined in patients infected with the other genotypes, particularly in those with genotype A or D infection.
Santa Monica Mountains National Recreation Area Custom Search This is a great wilderness vicinity that everybody likes. A visit to Santa Monica Mountains National Recreation Area is a great selection when you need to get out of the house. Camping is available at Camp Jca Sholom, and if you need a site to stay Quality Inn & Suites Thousand Oaks is a glorious choice. A splendid close by hotel is Best Western Thousand Oaks Inn, and if you're here, you could have a look at North Fork Arroyo Conejo. A golf course close to Santa Monica Mountains National Recreation Area is Sunset Hills Country Club; there's some flowing water close by, Arroyo Simi is a stream you can have a look at during your stay. There are many amusing pastimes for everybody. Santa Monica Mountains National Recreation Area is a popular destination for folks arriving from Thousand Oaks. Enjoy a round of golf at Max Out Golf not far from Santa Monica Mountains National Recreation Area; it's a nice idea to visit South Branch Arroyo Conejo. Camping at Camp Westoaks is always a glorious experience; obviously Arroyo Santa Rosa flows through this region. The majestic splendor of Santa Monica Mountains National Recreation Area is there for your viewing pleasure. Whohoo, so many enjoyable things in one place! Santa Monica Mountains National Recreation Area is great! Hmptn Inn and Suites Thousand Oaks is a pleasant spot to get some rest, and here at Santa Monica Mountains National Recreation Area you can spot Mount Clef. There is great outdoors recreation at Santa Monica Mountains National Recreation Area, so you may have a heap of fun. Having a good time at Santa Monica Mountains National Recreation Area is easy. The peak of Santa Monica Mountains can be distinguished from Santa Monica Mountains National Recreation Area. If you're here, you might as well stop by Happy Camp Canyon, and why not camp at Camp Keystone while you're here at Santa Monica Mountains National Recreation Area. Leo Carillo State Park is a perfect local campground, and Simi Peak is clearly visible from Santa Monica Mountains National Recreation Area. At Santa Monica Mountains National Recreation Area you always meet someone from Thousand Oaks. Westlake Golf Course is a splendid golf course close by; you might also want to pay a visit to Hidden Valley since you're here at Santa Monica Mountains National Recreation Area. All the outdoors exciting stuff in the vicinity of Santa Monica Mountains National Recreation Area will keep you coming back over and over. A range like the Santa Monica Mountains here at Santa Monica Mountains National Recreation Area is always delightful, and a quick tour to Lake Eleanor Creek is unquestionably a great idea. Hi, please take a look at the attached photo. I took it today in La Jolla Canyon, at the water fall (dry now). Notice that a large rock appears to be loose and or without support. It looks like the rock is supporting the trail above. Someone should take a closer look at that rock. In heavy rain it could come down. It looks unstable. - James R. Caballero, D.C.
"Knife is a dirty thief who always sneak into King Kinos palace to steal his treatures. She always success sneak in without any Royal Guards notice. But she always get caught all the times by the king himself. However, he always let her go everytime he caught her...and she always come back again and again..."Just an OC I made with an original species that belong to my friend. Unlike all other Lucretiar. She is a cold blood dragon that can't breath fire and can't summon aura weapon over her tail. But she is master in stealing because she can low her body temperature to the same as enviroment temperature and deep pale color also make it hard to notice her...Knife belong to me [Vavacung]Lucretiar tribe belong to DarkPotzm[ inkbunny.net/submissionview.ph…
Our Wet Cast & Pre Cast pavers are made by hand, one at a time, to ensure that the quality is maintained and every paver is scrutinized for flaws before they leave our premises. Origin Pavers are our go to range for domestic situations and are a very cost effective way of enhancing the outdoor living area of your home. The Paving Slab Co. is also able to supply the Bowers range of dry cast pavers.Read More… Need an old fashioned bird bath, a concrete sphere, or a nice big bollard to stop people driving across your berm? These all come in a variety of sizes so give us a call to discuss your requirements. We also stock tree rings, mowing strips and L-shaped garden edges. Read More… We take pleasure in producing ‘made to order’ products that are special to the purchaser. We have a number of moulds to create water features, so talk to us about that special feature and how we can help create a centre piece for your property or how you can incorporate a fabulous piece of water art into your garden. Read More… With age has also come experience and with the current staff and management we have both in truckloads. The Paving Slab Co. can produce the finest of new pavers or match to existing pavers that may be damaged or maybe you just want a few more to extend an outdoor living area. PAVING THE WAY Trying to match old Stevenson’s pavers that are no longer produced? This is a specialty we pride ourselves upon. McCallums Red Chip pavers that are becoming popular again are always in stock. Ask about our polished bench tops or those one off pool copings. Our pavers are made by hand, one at a time, to ensure quality is maintained and every paver is scrutinized for flaws before they leave our premises. They are suitable for domestic and commercial landscaping applications, indoor and outdoor.
Meat consumption, cancer risk and population groups within New Zealand. In comparison with other OECD countries with good cancer registries, New Zealand has the highest mortality rate of colon cancer, second highest of breast cancer and third highest of prostate cancer. A possible association with heterocyclic amine consumption has been suggested for each of these cancers. Studies of locally cooked meat suggest that the main contributors to heterocyclic amines in the New Zealand diet would be well-cooked beef, chicken and pork. Well-cooked beef steak, and the specific heterocyclic amine, IFP, showed a weak positive correlation with prostate cancer risk in the New Zealand population, but no studies thus far have considered the role of meat cooking practices or heterocyclic amines in the development of other cancers. The Maori and Pacific Island people, despite a superficially similar diet, have a substantially lower incidence of colon cancer than people of Caucasian origin. These differences are particularly intriguing in view of a report that a very high percentage of these people have a fast acetylator phenotype-a factor suggested to augment the effect of well-cooked red meat in other populations. The three population groups are known to differ in their preferences for meat type (including processed meats), and there are anecdotal suggestions that they may differ in preferred cooking methods. More detailed population studies are warranted to establish the role of meat, meat processing, cooking methods and the interaction with food plants and/or with genotype and phenotype in New Zealand.
import React from 'react'; import { shallow } from 'enzyme'; import assert from 'assert'; import WeUI from '../src/index'; const {CellHeader} = WeUI; describe('<CellHeader></CellHeader>', ()=> { ['cell header wording', <img src="http://mmrb.github.io/avatar/jf.jpg" />, <p>cell header wording</p>].map((child)=>{ describe(`<CellHeader>${child}</CellHeader>`, ()=>{ const customClassName = 'customClassName1 customClassName2'; const wrapper = shallow( <CellHeader className={customClassName}>{child}</CellHeader> ); it(`should have 'weui-cell__hd' class name`, ()=>{ assert(wrapper.hasClass(`weui-cell__hd`)); }); it(`should have custom class name ${customClassName}`, ()=> { assert(wrapper.hasClass(customClassName)); }); it(`should have child ${child}`, ()=>{ assert(wrapper.contains(child)); }); }); }); });
Please enable Javascript to use Kanopy! Show me how
using System.ComponentModel; using System.Runtime.CompilerServices; namespace CardIdleRemastered { public abstract class ObservableModel : INotifyPropertyChanged { public event PropertyChangedEventHandler PropertyChanged; protected virtual void OnPropertyChanged([CallerMemberName] string propertyName = null) { var handler = PropertyChanged; if (handler != null) handler(this, new PropertyChangedEventArgs(propertyName)); } } }
Personalized Bags: Before You Go When you go out, your style shouldn’t stay in. So let’s add some customization to your closet with an embellished clutch, tote or crossbody. Look here for loads of inspiration to get started. Then say goodbye to store-bought and hello to so-you.
Role of copper species in the oxidative dimerization of arylboronic acids: synthesis of symmetrical biaryls. Certain Cu(I) and Cu(II) salts are able to mediate the dimerization of arylboronic acids in DMF. They provide the corresponding symmetrical biaryls in moderate to very good yields. It is possible to run the reaction catalytically under an oxygen atmosphere without a significant loss of yields.
# babel-plugin-veui This Babel plugin enables you to wrtie simpler `import` statements by converting such statements: ```js import { Button, Input } from 'veui' ``` ...into: ```js import Button from 'veui/components/Button' import Input from 'veui/components/Input' ``` ...just like `babel-plugin-lodash` does. You can also use the following prefixed version to make it easier to register components using object property shorthand: ```js import { VeuiButton, VeuiInput } from 'veui' export default { components: { VeuiButton, VeuiIcon } } ``` ...or... ```js import { VButton, VInput } from 'veui' export default { components: { VButton, VIcon } } ``` So you can use `<veui-button>` or `<v-button>` in templates.
Q: alignment of div in css <span>Text</span> <div class="ui-icon ui-icon-circle-arrow-e abc" style=" display:block; border-width:2px; border-style:solid; border-color:red;"></div> <span>Text</span> <div class="ui-icon ui-icon-circle-arrow-e abc" style=" display:block; border-width:2px; border-style:solid; border-color:red;"></div> <span>Text</span> <div class="ui-icon ui-icon-circle-arrow-e abc" style=" display:block; border-width:2px; border-style:solid; border-color:red;"></div> <span>Text</span> <div class="ui-icon ui-icon-circle-arrow-e abc" style=" display:block; border-width:2px; border-style:solid; border-color:red;"></div> Will produce How can I format the above code to look like the following The property float: left is not working as I desired. If I use this for div, all the divs will come first. Then all the span will come second. A: Divs are block level elements so they take up an entire 'line' on the screen. You can set them to display: inline-block; instead. http://jsfiddle.net/nLMGT/
Description Shiprock has two of the longest climbs at Pictured Rocks(Somn Somn, Over the Counter), along with Tarzan a popluar first or second lead. Getting There From the Main trail walk past Wild Iowa Wall, past A Wall, The Comic Gallery, and Ice Cave Wall. Follow the high trail. You should come to a formation that that has a gully going up on the left and a trail leading down to the right, this is Shiprock, and the route you see is Tarzan. Easy climbing on good holds, the crux is between the third and fourth bolts requiring the climber to reach on not so good holds, great climb for the beginning leader or top roper....[more]Browse More Classics in IA Never fear as the trail gets a bit smaller and smaller the farther up river you go. Just stay between the cliffs and the water and you shall be fine. Very nice belay pad for tarzan to let you know that you are there. Also a large vine running up the side of the rock. Vine is not on. Kind of a landmark of sorts. OTC and Somn Somn are just to the right. There are now nice, cedar steps leading down the hill to Silk Road and Over the Counter. Cedar belays, too. This hillside has been a constant source of erosion troubles. The old RR ties have been removed. Please help this hillside come back into a state of vegetation and stick to the established trail. Thanks and enjoy.
Swollen hexagonal liquid crystals as smart nanoreactors: implementation in materials chemistry for energy applications. Materials are the key roadblocks for the commercialization of energy conversion devices in fuel cells and solar cells. Significant research has focused on tuning the intrinsic properties of materials at the nanometer scale. The soft template mediated controlled fabrication of advanced nanostructured materials is attracting considerable interest due to the promising applications of these materials in catalysis and electrocatalysis. Swollen hexagonal lyotropic liquid crystals (SLCs) consist of oil-swollen surfactant-stabilized 1D, 2D or 3D nanometric assemblies regularly arranged in an aqueous solvent. Interestingly, the characteristic size of the SLCs can be controlled by adjusting the volume ratio of oil to water. The non-polar and/or polar compartments of the SLCs can be doped with guest molecules and used as nanoreactors for the synthesis of various metals (Pt, Pd, Au, etc.), conducting polymers and composite nanostructures with controlled size and shape. 1D, 2D and 3D mono- and bimetallic nanostructures of controlled composition and porosity can also be fabricated. These materials have demonstrated impressive enhancements of their electrochemical properties as compared to their bulk counterparts and have been identified as promising for further implementation in energy harvesting applications. In this review article, recent research materials are described regarding the development of functional materials with much improved performances for catalysis applications. This review addresses a brief overview of swollen hexagonal mesophases as nanoreactors, describes examples of nanostructured materials synthesized in these nanoreactors, shows several examples of the energy conversion applications in solar light harvesting, fuel cells etc. and also summarizes the associated reaction mechanisms developed in the recent literature for enhanced catalytic activity.
Colin Kaepernick kneeled during the playing of the US national anthem at NFL games to bring attention to racial injustice in America. Now he is being blackballed because he did so. Fans are ready to protest if he is not signed. DiscussBury
Q: Ionic: how can I access constructor objects from nested methods? I am using leaflet to render a map, and leaflet draw to draw shapes. I am able to draw & save shapes as well as retrieve them. I am struggling how to interact with the retrieved shapes. In my specific case, I want to init a popover. myfile.ts constructor(public popoverCtrl: PopoverController) {...} drawShape(data) { let shape = {...} // has geometry etc. L.geoJSON(shape, { onEachFeature: this.onEachFeature }).addTo(this.myMap); } onEachFeature(feature, layer) { layer.on('click', function (e) { let popover = this.popoverCtrl.create('MyComponent', { layer: event }); popover.present(); }); I can't get to this.popoverCtrl since it's in a different scope than the constructor. How can I get access to the popover component? Thank you for any suggestions! A: So you need to deal with ‘this’ in your case. For that you can use fat arrow functions to do that as they do not create their own “this” unlike anonymous and other functions: see in the layer.on part where i did the change going from anonymous to fat arrow function: onEachFeature(feature, layer) { layer.on('click', event => { let popover = this.popoverCtrl.create('MyComponent', { layer: event }); popover.present(); }); Sometimes you will still have issues “getting to” the “this” you need from your component method if you sort of traverse through various execution contexts. In such cases you can also do this trick in your component methods: assign method through variable onEachFeature = (feature, layer) => { layer.on('click', event => { let popover = this.popoverCtrl.create('MyComponent', { layer: event }); popover.present(); }); This basically prevents your methods from creating their own “this” context. PS: please note that your code defines event differently in argument of function and then in the code (e vs event) i hope you can fix that
Treatment of acute gastroenteritis: too much and too little care. This paper reviews the health services literature regarding care for gastroenteritis in children. United States health care utilization, use of oral rehydration therapy (ORT), and quality of care considerations are described. The literature suggests that some US children may receive too much care while others may not be getting enough and that physician practices continue to differ from expert recommendations.
This is a list of Bot::Backbone::Service::Role::ChatConsumers that hvae registered to receive messages from this chat service. A chat consumer is registered using the register_chat_cnosumer method. A list_chat_consumers method is provided to list the registered consumers. Sends a message to a group or individual using this chat service. This is used when the message is not being made as a direct reply to a message received from the chat service. If both group and to are passed, the preference should be to send to the group. This role also provides a wrapper around your chat's implementation of send_message, which will apply the current service's send policy to the message. The most restrictive send policy encountered at any point will win. A send policy may be explicitly provided by setting the send_policy setting in the parameters to a Bot::Backbone::SendPolicy object. Missing this parameter will result in an error. The send_policy_result may also be set to reflect the most restrictive send policy result encountered so far. Given a message generated by this chat service, this should send a reply to the origin of the message, whether that be a group or individual or other entity. The second argument is a hash reference of options, which is used to modify the reply further. See "send_message" for additional options and be aware that individual chat implementations may provide more options in addition to those shown here.
Q: Implement Microsoft Outlook Calendar on a private project As the title implies, I'm trying to implement Microsoft's Graph API. So far I've implemented everything I need except for the Calendar. My problem is that I can't seem to implement any REST methods for their calendar. My project is built using Angular and I am stuck at where to go to implement their calendar fully. A: Fixed it by making the calendar grab events from your account session and by fixing permissions in Azure AD. Then I made the calendar list your events and show them as dots on the calendar. Easy fix that took way too long but it's a private project, thankfully I didn't abandon it.
MP Alec Shelbrooke has told the Wetherby News that he is prepared to be “the last man standing” as he gets ready to argue against Leeds City Council’s Site Allocations Plan at a public examination next month.
Q: Additional Autonumber in an SQL table that has an identity How do I get an additional auto-number in my SQL table. I already have an IDENTITY column, but i need an additional column that also auto-increments. A: There are a set of ranking functions that you can use for this. For instanse, you can use the ROW_NUMBER() function like so: SELECT *, ROW_NUMBER() OVER (ORDER BY somefield) rownum FROM table;
With the advent of electronic calendars on computer systems, users of the calendar may assign a multitude of attributes to an event scheduled thereon. For example, if an event is a meeting or a class, it is possible to include attributes/information such as the identity of attendees, duration of the meeting or class, number of seats required, whether a projector or overhead is needed, and etc. As an event becomes more complicated in terms of resources and equipment, additional attributes may be created and added. Also, there are scheduling programs (scheduler) that can be used in conjunction with a calendar. For example, a scheduler can be used to search for a vacant classroom or meeting room (facility). The search results typically present a user with a listing of alternative openings (i.e., time slots) for each facility searched. If there are required attributes for the facility, such attributes may be used in the search to ensure the facility available meets those requirements. However, the calendar user must specify attributes individually for each calendar event. In many cases, a user may find that the attributes relating to the event's facility (i.e., classroom or meeting room) for a new event are identical to those required by a previous calendar event. Presently, there is no simple way to allow a user to replicate the same facility attributes for different events. For example, a user may need a slide projector, speaker phone, and seating for eight for multiple but different meetings. The user must manually respecify these attributes for each of the meetings, which may be both time-consuming and tedious, before initiating a search on a scheduling program. Thus, there is a need for a mechanism by which the same attributes may be saved and assigned to multiple meetings/classes.
Q: Query to return customer order history? I am trying to dump historical customer order data from a legacy ecommerce site that we restored from an AMI. Ideally this would grab customer ID, email, order date, product SKUs ordered, and order totals. Is this possible to do through a straight sql query or would we be better off fixing the broken PHP framework and exporting from Magento? A: It really depends on your version of Magento and whether there are flat sales tables or not. If there are flat sales tables, then straight SQL is: select e.*,sfoi.* from sales_flat_order e left join sales_flat_order_item sfoi on (e.entity_id=sfoi.order_id) where e.customer_email = '[your_customer_id]'; Via the object model: $customer_email = 'youremail@gmail.com'; $collection = Mage::getModel('sales/order') ->getCollection() ->addAttributeToFilter('customer_email',array('like'=>$customer_email)); foreach($collection as $order){ //do something echo $order->getCustomerEmail(); }
mod pipe_read; mod pipe_write; pub use self::pipe_read::PipeRead; pub use self::pipe_write::PipeWrite;
The rising demand for bioethanol, the most common alternative to petroleum-derived fuel used worldwide, has encouraged a feedstock shift to non-food crops to reduce the competition for resources between food and energy production. Sweet sorghum has become one of the most promising non-food energy crops because of its high output and strong adaptive ability. However, the means by...
Role of penicillin-binding protein 1b in competitive stationary-phase survival of Escherichia coli. The penicillin-binding proteins (PBPs) catalyze the synthesis and modification of bacterial cell wall peptidoglycan. Although the biochemical activities of these proteins have been determined in Escherichia coli, the physiological roles of many PBPs remain enigmatic. Previous studies have cast doubt on the individual importance of the majority of PBPs during log phase growth. We show here that PBP1b is vital for competitive survival of E. coli during extended stationary phase, but the other nine PBPs studied are dispensable. Loss of PBP1b leads to the stationary phase-specific competition defective phenotype and causes cells to become more sensitive to osmotic stress. Additionally, we present evidence that this protein, as well as AmpC, may assist in cellular resistance to beta-lactam antibiotics.
[Xanthine lithiasis in a case of Lesch-Nyhan syndrome treated with allopurinol]. Classically it is considered that vital prognosis of Lesch-Nyhan syndrome depends on renal affectation secondary to uric nephropathy. A case of Lesch-Nyhan syndrome treated with Allopurinol is described which presented multiple and bilateral renal stones by precipitation of xanthine. Treatment with Allopurinol inhibits the formation of uric acid and qualitatively renal excretion of oxypurines modifies. In special circumstances (disminution of urinary output and pH), they can precipitate and originate a radiotransparent lithiasis with uric lithiasis. Interest of this case, lies in being alert to possible xanthine stone formation in patients with a large excretion of purinics metabolites, who are treated with Allopurinol.
The column was taken down from the newspaper’s website. It should not have been. How can the rest of us assess its arguments absent an authoritative version of the writing? The student body president has called for defunding the student newspaper. He should not be advocating punishing speech he does not like. A few hundred people have signed an online petition calling for the paper to be defunded. But let’s say I proposed an online petition to take away the right to petition the government “for redress of grievances.” If several hundred people sign my petition, would it be right? No, it would deeply offend the First Amendment. Now imagine there was a “hate speech” exception to the First Amendment. Would such an exception allow public officials to censor “Your DNA is an Abomination?” The author apparently wrote: Ontologically speaking, white death will mean liberation for all. To you good-hearted liberals, apathetic nihilists and right-wing extremists: accept this death as the first step toward defining yourself as something other than the oppressor. Until then, remember this: I hate you because you shouldn’t exist. You are both the dominant apparatus on the planet and the void in which all other cultures, upon meeting you, die. So does using the verb “hate” in regard to a group of people constitute “hate speech?” Or are such statements only subject to censorship if the speaker is an “oppressor” but not if they are one of “the oppressed?” Who decides which speakers belong in which categories and thus who can use the verb and who cannot? The courts? Legislatures? We do know this. Absent a hate speech exception to the First Amendment, this essay has been pulled from a website, its editors have apologized, and the highest-ranking public official involved seems to be obliquely threatening the newspaper and the author of the essay. If “hate speech” were not protected by the Constitution, what would have happened?
Hellgrammite Hellgrammite may refer to: Hellgrammite (comics) Hellgrammite, the larval form of the dobsonfly
•This Keypad is mainly used for unsupervised or semi-supervised positions of varied access applications, internet terminals and information kiosks at universities, shopping malls, hotels, banks, airports, railway-stations and other public areas.
Cast in Shadow Seven years ago Kaylin fled the crime-riddled streets of Nightshade,knowing that something was after her. Children were being murdered -- and all had the same odd markings that mysteriously appeared on her own skin... Since then, she's learned to read, she's learned to fight and she's become one of the vaunted Hawks who patrol and police the City of Elantra. Alongside the winged Aerians and immortal Barrani, she's made a place for herself, far from the mean streets of her birth. But children are once again dying, and a dark and familiar pattern is emerging, Kaylin is ordered back into Nightshade with a partner sheknows she can't trust, a Dragon lord for a companion and a device to contain her powers -- powers that no other human has. Her task is simple -- find the killer, stop the murders... and survive the attentions of those who claim to be her allies!
Neurobiological evidence for abstract phonological representations in the mental lexicon during speech recognition. A central issue in speech recognition is how contrastive phonemic information is stored in the mental lexicon. The conventional view assumes that this information is closely related to acoustic properties of speech. Considering that no world is ever pronounced alike twice and that the brain has limited capacities to manage information, an opposing view proposes abstract underspecified representations where not all phonemic features are stored. We examined this propos.al using event-related brain potentials, in particular mismatch negativity (MMN), an automatic change detection response in the brain that is sensitive to language-specific phoneme representations. In the current study, vowel pairs were presented to subjects, reversed as standard and deviant. Models not assuming underspecification predict equal MMNsfor vowel pairs regardless of the reversal. In contrast, enhanced and earlier MMNs were observed for those conditions where the standard is not phonologically underspecified in the mental representation. This provides the first neuro-biological evidence for a featurally underspecified mental lexicon.
Q: how to display categories in layered navigation magento? already set up my categories as anchors active My attributes are displayed correctly, more categories are not displaying. can anyone help me? thank you A: Please double check if the categories you want display is not empty. Magento hide the empty Categories.
Cristiano Ronaldo’s Nike FC CR7 Releasing Soon Cristiano Ronaldo has recently made news by leaving Real Madrid and taking his talents to Juventus. With the move making global news, Nike has already designed a brand new sneaker for their elite soccer player, the Nike FC CR7. Advertisment Dressed in a Black and Gold color scheme. This FC CR7 features a Black mesh upper with Gold detailing along the mudguard, Nike Swoosh, and heel. A Black React midsole, embroidered CR7 branding on the tongue, suede paneling on the heel atop a Gold icy outsole completes the design. Nike FC CR7 Release Date No release date has been set, but you can expect to see the Nike FC CR7 debut soon than later at select retailers and Nike.com.
"Wake up!" "This is no place to sleep." "Step back, you reek." "If you want me to read you the letter, step back." "It's from your old lady." "She says she really loves you." "But she has needs, and the wait is long." "So she's already fucking some other asshole." "That's life, Chapo." "I feel the warmth from my boiling blood" "I feel the fear sweat dripping away" "There's a stillness that nothing transmits" "I'm a breeze that grows stronger" "Even when the clouds drift away" "Even when my skin dries away" "I'll be back someday" "To unleash my return" "I have the dust that protects the road" "I have the branches of a leafless tree" "I'm the one guarding over the tired night" "There are silhouettes that come to see me" "Even when clouds drift away" "Even when my skin dries away" "I'll be back someday" "To unleash my return" "Let me go!" "Where are you taking me?" "Wait!" "I'm the Deputy Director of this prison." "You've spent a month in isolation because I gave the order." "I'll decide whether you stay in there or not." "Let me ask you just one question." "Do you promise to live a different life?" "Do you agree that so much luxury, money, and power was a mistake?" "You can look me in the eyes to answer me." "Yes, Deputy Director." "I promise I've changed." "Take him back, one more month." "Wait, ma'am!" "I'll take revenge!" "Be harsher with your discipline." "Make it clear to him that he's in Almoloya." "No, no!" "No!" "No, no, no!" "No!" "Turn it off!" "Turn it off!" "I have a stomachache." "I have a stomachache!" "I have a stomachache." "I have a stomachache!" "Hey..." "Deputy Director." "El Chapo has not been eating for several days and he says he has a stomachache." "Take that off and take a shower." "I left you a clean uniform." "Lay down on your back." "If you tell them it's serious, I'll pay you a shitload of money." " I can pay you a lot." " How much?" "You set the price." "You just have to convince them to take me back to my cell." "The pain will go away if you eat." "Do me the favor, doc." "All right." "No!" "A message from the Deputy Director." "For trying to bribe the doctor, you've just won yourself two more months in here, asshole." "No, please, no!" "No!" "I'll do whatever you want!" "Take me out of here!" "Deputy Director, I swear I've changed!" "Deputy Director!" "Deputy Director!" "I swear I won't live like I used to." "Deputy Director!" "Keep pressuring Mr. Guzman." "I want to know everything he says or does." "Understood." "Give me what's in your pockets." "I don't have anything." "No." "It's just a thread." "Do you think you are the first one to try this?" "You're counting the days to see when you're out, right?" "You just have to ask me." "Chapo... you'll never leave this place, son of a bitch." "Deputy Director, Joaqui­n Guzman has once again attacked the authorities of this prison." "Very good, Chapo." "Take good care of your plants." "Mr. Pedro will need more opium gum." "Of course." "I think these will do for two more harvests." "Thank you." "You're better at this than your dad." "Mom." "I'll get the same or more with the other two harvests." "Great, my son." "Go hide it." "What's up?" "What?" "You thought I wouldn't find out about the money from the harvest?" "I earned it." "It's mine, not yours." "Who taught you how to farm it, you ungrateful punk!" "Joaqui­n." "Joaqui­n." "Son, go and get your father." "Come on." "Bye." "Tauro Hardware Store" "Hey!" "Hey!" "Get away from the car." "This car needs to be properly cleaned and waxed." "I can do it." "How much?" "You can name the price." "I can even clean the interior." "There's some buckets and water there." "Come on!" "Okay." "Son of a bitch!" "Come on, Pancho!" "Get in!" "Get out, son of a bitch!" "Get out of the car!" "Get out!" "Come on!" "Pancho, get in the car!" "Come on, punk!" "Did you want to steal my car, fucking punk?" "No, sir." "I only wanted to go for a ride and see how it felt to drive such a car." "I wouldn't steal from you, Mr. Pedro." "I want to have that same car." "That's why I want to work for you." "You go for a ride in my car, and now you're asking for work?" "Yes." "What's your name?" "Joaqui­n Guzman." "But everybody calls me El Chapo." "You're the one who is taking good care of the poppy field?" " That's right." " Then you're already working for me." "No, Don Pedro," "I can do much more than just taking care of the fields." "I want to do more." "If you want to join me, you've got to earn it." "Tell me what to do." "What do I have to do to earn myself a place?" "There's someone who is stealing money from me." "I can't stand those things." "I want you to kill him." "I bet he won't do it." "I bet he will." "Have you used one before?" "You're going to lose the bet, buddy." "Get out." "Damn!" "Chapo, what's up?" "What are you doing?" "Damn it!" "You did better than I thought." "You killed him!" "Come here." "Boss." "Welcome to my organization." "Tomorrow we'll go to Culiacan." " You're coming with me." " Thank you, Don Pedro." "Now go and have some fun." "Enjoy the party." "Hold this." "Take this." "The guys at the back, the ones all dressed up, are the DEA guys." "The guys standing over there are the politicians." "Be careful with them." "They're the real assholes." "Those guys are the military men." "They take care of the fields and watch our backs." "No crooked games with them." " Your package, boss." " Let me see." "That's it!" "Look!" "Fresh from the ocean, just as we like it!" "For all of you to eat!" "Long live Don Pedro!" "Yeah!" "More tequila." " Hurray!" " Hurray!" "I know that I'm out" "But the day I die" "I know you'll be crying" "Crying and crying" "Crying and crying" "You'll say you never loved me" "But you're going to be really sad" "And sad you're going to stay" "With or without money" "I always do what I want" "And what I say goes" "I have no throne or queen" "Nobody understands me" "But I still remain the king" "Long live Mexico, assholes!" "Long live Mexico!" "When you have money... you have power." "When you have power... everybody wants to be with you." "Your mom says you're going to work for Pedro Aviles in Culiacan." "Don't pack, you're not going anywhere." "Go!" "Leave!" "You're just going to be one more servant to a drug lord." "Just a fucking servant." "I'm going to have more power than anybody else." "I'm going to become the most powerful drug lord." "Did you get that?" "I can swear on that!" "Four months locked up." "Surely that was enough." "You've behaved." "Do you promise to live a different life?" "Do you agree that so much luxury, money, and power was a mistake?" "Yes." "Take him to his cell." "Chapo." "Chapo." "We thought you were dead." "Wake up!" "You're not on vacation!" "Ruben was never himself again." "They took him to a special area." "Chapo." "What'd they do to you?" "They kept you all these months in isolation?" "Silence!" "Enrique." "Contreras Vidal." "Joaqui­n." "Guzman Loera." "Permission to speak, sir." "Speak." "Sir." "Is it true that there is community work in the prison?" "I'd like to work." "Anything is fine." "I tell the Deputy Director who deserves to work and who doesn't." "Believe it or not, it's like a prize." "Yes, sir." "Adrian." "Velazquez Saavedra." "Where should I put the bags?" "Container in the backyard." "Joaqui­n." "I came every two weeks." "They didn't let me see you." "I filed defense statements, but it was useless." "Don't worry." "I'm fine now." "Better than before." " Hello." " Buddy." "What's up, buddy?" "How are they treating you?" "Do you remember the party we had for Mr. Palomino?" "Yes, of course I remember." "Could you please organize a similar party?" "This time is for Lora's wife." "She's a nice girl and she's been helping him out a lot." "Please, help me with that." "That's him." "I won't hurt you, buddy." "On the contrary..." "I'll reward you if you do as I say." "I'm going to escape." "Joaqui­n, unless they transfer you to another prison... escaping is impossible." "I'm going to escape using the trucks that enter though the back gate." "We need a false floor in the truck." "And we need to bribe the driver, the loaders, and the guards." "Ask Ismael for the money." "Joaqui­n, this is crazy." "I don't care how long it takes me, I'm going to be free again." "C5, keep I3 in red." "Message received." "Are you going to open the door?" "Bring him." "I'm going to escape using the trucks that enter though the back gate." "We need a false floor in the truck." "And we need to bribe the driver, the loaders, and the guards." "Ask Ismael for the money." "You're very naive if you think I trust people." "Everything is being monitored, Mr. Guzman." "That's why nobody can escape from Almoloya." "Take him back to isolation." "No!" "You may say you never loved me" "But you're going to be really sad" "And sad you're going to stay" "With or without money" "I always do what I want" "And what I say goes" "I have no throne or queen" "Nobody understands me" "But I still remain the king"
STAT5 transcriptional activity is impaired by LIF in a mammary epithelial cell line. Gene regulation mediated by STAT factors has been implicated in cellular functions with relevance to a variety of processes. Particularly, STAT5 and STAT3 play a crucial role in mammary epithelium displaying reciprocal activation kinetics during pregnancy, lactation and involution. Here, we show that LIF treatment of mammary epithelial HC11 cells reduces the phosphorylation levels and transcriptional activity of p-STAT5 in correlation with STAT3 phosphorylation. We have also found that STAT5 activity is negatively modulated by this cytokine, both on a gene whose expression is induced, as well as on a promoter repressed by STAT5. Besides, our results show that lactogenic hormones increase LIF effect on gene induction without modifying STAT3 phosphorylation state. Our findings strongly suggest that there is crosstalk between STAT5 and STAT3 pathways that could modulate their ability to regulate gene expression.
package org.openalpr.model; /** * Coordinate model. */ public class Coordinate { private final Integer x; private final Integer y; public Coordinate(Integer x, Integer y) { this.x = x; this.y = y; } /** * Gets the X coordinate. * * @return The X coordinate. */ public Integer getX() { return x; } /** * Gets the Y coordinate. * * @return the Y coordinate. */ public Integer getY() { return y; } }
Depth of Extinction Depth of Extinction is a retro RPG with a modern turn-based, tactical combat system. Recruit and lead your team on raids in undersea habitats containing all that remains of humanity. Find cover and attack enemies but be careful because every move is critical if you want to keep your team alive.
Okay, so if that's not real, what is? What counts, to you?" He thought for a second, then said, "I don't know. Just because someone's pretty doesn't mean she's decent. Or vice versa. I'm not into appearances. I like flaws, I think they make things interesting." I wasn't sure what answer I'd expected. But this wasn't it. For a second, I just sat there, letting it sink in. "You know," I said finally, "saying stuff like that would make girls even crazier for you. Now you're cuteand somewhat more attainable. If you were appealing before, now you're off the charts.
Random binding of dimers to chains. We develop a probabilistic model for the binding of a small linear polymer to a larger chain. We assume that we can approximate the energy of interaction of the two chains by summing the pairwise interactions between subunits. Because the energy of interaction between a pair of subunits can depend on neighboring subunits, which we assume vary along the chain, we assign the pairwise energies of interactions according to a specified probability distribution. Thus we develop a statistical model for the binding of two molecules. While such models may not be appropriate for studying the interaction of a particular pair of molecules, they can provide insight into questions that deal with populations of molecules, such as why do MHC molecules bind peptides of a certain size? Here we analyze in detail the special case of a heterodimer binding to a polymer.
Universal curve The term universal curve is used: In the mathematical field of fractals and curves: Menger sponge To describe the Inelastic mean free path of electrons in solids. A universal object for the moduli of curves.
/** * Namespace for color-related utilities. * @namespace commons.color * @memberof axe */ export { default as centerPointOfRect } from './center-point-of-rect'; export { default as Color } from './color'; export { default as elementHasImage } from './element-has-image'; export { default as elementIsDistinct } from './element-is-distinct'; export { default as filteredRectStack } from './filtered-rect-stack'; export { default as flattenColors } from './flatten-colors'; export { default as getBackgroundColor } from './get-background-color'; export { default as getBackgroundStack } from './get-background-stack'; export { default as getContrast } from './get-contrast'; export { default as getForegroundColor } from './get-foreground-color'; export { default as getOwnBackgroundColor } from './get-own-background-color'; export { default as getRectStack } from './get-rect-stack'; export { default as hasValidContrastRatio } from './has-valid-contrast-ratio'; export { default as incompleteData } from './incomplete-data'; export { default as getTextShadowColors } from './get-text-shadow-colors';
The formation of integrated circuit often involves etching metal layers. For example, aluminum-containing gate electrodes and aluminum copper pads are commonly seen integrated circuit components. These components are formed by depositing a blanket metal layer, and then patterning the blanket metal layer as desirable patterns using an etching process. The etching of the metal layer may be performed in a dry etching chamber, which is vacuumed, and etching gases are introduced into the etching chamber to etch the metal layer. In the etching process, plasma is generated from the etching gases. The metal ions in the metal layer may sometimes react with the ions in the etching gases to form particles. For example, when aluminum is etched, the aluminum ions may react with fluorine ions to form aluminum fluorine (AlF) particles, which stick to the inner surface of the etching chamber. The bonding of the AlF particles to the inner surface of the etching chamber, however, is weak. Hence, the bonds between the AlF particles and the inner surface may break, and the AlF particles fall on wafers, causing manufacturing yield to drop. AlF has a high vaporizing temperature. Hence, it is difficult to remove the AlF particles.
Transition from phase to generalized synchronization in time-delay systems. The notion of phase synchronization in time-delay systems, exhibiting highly non-phase-coherent attractors, has not been realized yet even though it has been well studied in chaotic dynamical systems without delay. We report the identification of phase synchronization in coupled nonidentical piecewise linear and in coupled Mackey-Glass time-delay systems with highly non-phase-coherent regimes. We show that there is a transition from nonsynchronized behavior to phase and then to generalized synchronization as a function of coupling strength. We have introduced a transformation to capture the phase of the non-phase-coherent attractors, which works equally well for both the time-delay systems. The instantaneous phases of the above coupled systems calculated from the transformed attractors satisfy both the phase and mean frequency locking conditions. These transitions are also characterized in terms of recurrence-based indices, namely generalized autocorrelation function P(t), correlation of probability of recurrence, joint probability of recurrence, and similarity of probability of recurrence. We have quantified the different synchronization regimes in terms of these indices. The existence of phase synchronization is also characterized by typical transitions in the Lyapunov exponents of the coupled time-delay systems.
The present invention relates to improvements in dryer drums for paper making machines, and more particularly to an improved mechanism for removing the water condensate which forms on the inner surface of the drum shell from condensing steam and which reduces the heat transfer from the steam within the shell to the surface of the shell for drying a traveling fibrous web. In a drying drum for a paper making machine, the mechanism includes a cylindrical shell with heads that have shafts for rotational mounting of the drum. A steam supply gland is provided to direct heated steam into the interior of the drum and generally dipper tubes or straws are positioned adjacent the inner surface of the drum to remove condensate which forms against the drum. In the formation of a relatively wide web of paper, the length of the drums has to be substantial, and it is essential for uniform drying that the drum have uniform heat along its length. Since the layer of condensate which forms within the drum reduces heat transfer from the steam to the metal of the drum shell, it is essential that this condensate layer be maintained as thin as possible, but more importantly, that it may be maintained of uniform thickness because if nonuniformity exists, different rates of heat transfer will exist along the length of the drum resulting in temperature differences and differences in dryness of the paper web along its width. It is accordingly an object of the present invention to provide a means for removing a maximum amount of rimming condensate and removing it very uniformly to maintain a uniform thickness layer and to avoid the adverse effects of heat expansion and contraction which change the spacing between the condensate removal means and the inner surface of the drum shell. Drying drums for paper making machines are often provided internally with narrow circumferential grooves spaced axially along the inner surface of the shell to leave a series of ribs or lands therebetween. These ribs strengthen the relatively thin shell of the dryer drum, and permit the safe use of a significantly thinner shell through which heat transfer is improved with a consequent increase in efficiency of the drying action on the paper or other web. Condensate is removed from within such drying cylinders through one or more header tubes carrying a plurality of dipper pipes or straws extending into the grooves and drawing off the condensate as it collects in such grooves. It has been found that, with wide machines having axially long drying cylinders, uneven moisture profiles of the dried web are often present, due to an uneven drying effect across the width of the machine. This uneveness is undesirable, particularly in thin webs, such as tissues, and it is believed that it results from uneven extraction of the condensate due to distortion of the dipper-carrying, condensate-removal header pipes. If, as is generally the case, these pipes are of substantial length, extending across substantially the full axial length of the cylinder, there is a tendency for them to distort locally when hot, and their spacing relative to the inner periphery of the cylinder shell to vary across the width of the cylinder. In this way the positioning of the dipper tubes or straws within the grooves varies, and hence condensate removal through these tubes may vary across the cylinder, producing temperature gradients across the smooth outer drying surface of the cylinder. Attempts to minimize this disadvantage by altering the lengths of the dipper tubes or straws has proved unsuccessful as the temperature gradient across the cylinder may vary according to running conditions of the machine. The present invention seeks to obviate or reduce the aforementioned difficulty by maintaining the setting distance between the end of each dipper and the inner surface of its associated groove in the shell of the dryer thereby to achieve an even depth of condensate layers. This is achieved by splitting the dipper-carrying tubes into several individual sections, each serving a part-only of the condensate removal across the width of the cylinder, whereby any distortion is minimized. According to the present invention the dipper tubes or straws across the or each condensate collection region within an internally grooved drying cylinder are carried from a plurality of individual short header tubes which together extend across substantially the whole axial width of the cylinder at said collecting region, the individual short header tubes being connected to one or more common header pipes arranged to lead condensate away from the individual short header tubes into a condensate discharge. Conveniently the short header tubes are slightly staggered across the width of the cylinder at the or each collection region to facilitate mounting of the tubes while still ensuring that each groove across the region has a dipper tube or straw projecting therein. Preferably the connections between each short header tube and the common header pipe are flexible, and this eliminates or reduces problems resulting from expansion of the tubes and pipes. The short header tubes are fastened to the shell locally and hence are able to follow changes in the shape of the dryer resulting from the application of a wet sheet thereto which tends to cause distortion of the dryer especially at the ends. With this local fastening it is possible to maintain the same accurate setting distance of the dipper tubes or straws within their respective grooves. An additional advantage stems from the use of separate common header pipes because flooding of the header in the vicinity of the riser tubes is thereby avoided. By using a plurality of short header tubes overall manufacture is less exacting inasmuch as accurate location of the dipper tubes or straws within the grooves is less difficult with the short sections than with a single long length. Moreover, the use of short sections of header tube enables internal erosion plates to be changed without removing the headers from the shell. While the above discussion relates primarily to dryer cylinders or drums which have grooves on the inner surface, the concepts of the invention apply equally to drums which have a smooth inner surface inasmuch as the objective must be to maintain uniform heat transfer from the steam to the metal of the drum shell at all axial locations and to maintain this by maintaining a uniform thickness of condensate at all axial locations along the drum length. It is an object of the present invention to provide a condensate removal means which is so constructed that heat expansion and contraction of the parts will not cause axial displacement of the condensate removal means either axially or radially relative to the drum surface. It is a further object of the invention to provide an improved mechanism which provides dipper straws with open condensate receiving ends adjacent the inner surface of the shell of a dryer drum wherein the straws are individually divided, or divided in groups, which individual straws or groups are rigidly positioned relative to the inner surface of the shell so that heat expansion of the individual straws or individual groups along a relatively long length of dryer drum does not displace the straws or groups of straws so as to change their effective location with respect to their ability to remove condensate. Other objects, advantages and features, as well as equivalent structures which are intended to be covered herein, will become more apparent with the teaching of the principles of the invention in connection with the disclosure of the preferred embodiments thereof in the specification, claims and drawings, in which:
The present invention generally relates to parse/build engines and more specifically to a high performance and yet very flexible parse/build engine capable of translating multi-format message streams into an internal message format for processing and translating the internal message format back to the multi-format message streams where formats that can be translated may be dynamically added to the parse/build engine. Applications need to communicate with other heterogeneous systems when performing tasks. These heterogeneous systems may use data in a format that is different from the internal format of the host application. In order to be able to process information received in the different data format, the host-application may have to parse the external data format to its own internal data format. The host application can then process the parsed information in the internal data format. After processing, the processed information is then built into the external data format. Accordingly, the software application can then effectively communicate with external heterogeneous systems that process data in a different data format than the internal data format used by the software application. Conventionally, parse/build engines are used for the parse and build steps described above. The engines are generally one of two types, interpreter-based parse/build engines and compiled parse/build engines. Interpreter-based parse/build engines can handle multiple data formats. The interpreter-based parse/build engines include a large grammar dictionary that is used to interpret a certain set of messages. Accordingly, multiple data formats can be handled, but at the cost of performance because using the grammar dictionary is often very complex and translating messages using it degrades performance. Another drawback with the interpreter-based parse/build engines is they can only interpret the certain set of messages included in the grammar dictionary. If additional definitions in the grammar dictionary need to be added, the engine typically has to be recompiled in order to use the new definitions for the grammar dictionary. Compiled parse/build engines are customized for high performance for a fixed set of data formats. But compiled parse/build engines cannot support new data formats dynamically. They require code changes to incorporate the new data formats that may be necessary to support new business requirements. The code changes must then be recompiled. Thus, compiled parse/build engines are not a good fit for systems that need to handle new message types dynamically and cannot be brought down for re-compiling.
From Evil Flowers:Emi has a friend she keep in contact via text messages, Kei. They promised to met in the summer but Kei didn't come. It turns out Kei has actually passed away! So who has been messaging Emi? And at the same time, Emi meets Kazumi who reminds her of Kei. Who exactly is Kazumi?
The 'balanced force' concept for instrumentation of curved canals revisited. The principal characteristics of K-type files are described and the succession of operations as prescribed by the 'balanced force' method of preparation of root canals, particularly curved root canals, examined. On the basis of a simple mathematical model, the motions of a file in a straight canal and in a curved canal are successively considered, and the merits of the recommended method highlighted and confirmed.
wouldn't let me review this when I first read it, but that just gave me a chance to read it again. Writing this from Spike's POV was pure genius; not only is he a savvy judge of people, he's also in the forced possition of observer. He would also, naturally, take the whole situation personally, although the addition of memories of his mothers was an insightful surprise.
Q: Why is this simple Javascript refactor not working? A simple question about a form submit in HTML. Why does this work: var inputStuff = document.getElementById("inputBox"); var output = document.getElementById("outputBox"); function useMethod(element) { output.innerText = inputStuff.value; return false; } But this doesn't: var inputStuff = document.getElementById("inputBox"); var output = document.getElementById("outputBox"); function useMethod(element) { var out = output.innerText; var into = inputStuff.value; out = into; return false; } Here's the HTML: <h1>Put your input in here</h1> <form onsubmit="return useMethod(this)" action=""> <input type="text" id="inputBox"> <input type="submit" value="Submit"> </form> <h2>Output:</h2> <p id="outputBox">Starter text</p> Many thanks in advance for any help, R A: out = into; will simply assign the value of into (string) to out (string), whereas output.innerText = inputStuff.value; will invoke an implicit setter that will change the DOM value as well.
// -*- C++ -*- TAO_BEGIN_VERSIONED_NAMESPACE_DECL ACE_INLINE TAO_EC_Kokyu_Filter_Builder:: TAO_EC_Kokyu_Filter_Builder (TAO_EC_Event_Channel_Base *ec) : event_channel_ (ec) { } TAO_END_VERSIONED_NAMESPACE_DECL
A fully featured gantt chart component built entirely in Javascript, CSS and AJAX. It is lightweight and there is no need of external libraries or additional images. You can view a live example at https://jsGanttImproved.github.io/jsgantt-improved Features include: * Tasks & Collapsible Task Groups * Dependencies * Task Completion * Task Styling * Milestones * Resources * Dynamic Loading of Tasks * Dynamic change of format: Hour, Day, Week, Month, Quarter * Load Gantt from XML * From external files (including experimental support for MS Project XML files) * From JavaScript Strings * Support for Internationalization (all hard coded strings can be overridden) Project forked as I was unable to contact the original maintainers. This work was done to support a personal project that didn't warrant a more heavyweight system (e.g. the dojo toolkit gantt chart features). See the [Documentation](https://github.com/jsGanttImproved/jsgantt-improved/wiki/Documentation) wiki page or the included ``index.html`` file for instructions on use.
Structural optimization of cyclic peptides that efficiently detect denatured collagen. To develop a facile method for detecting denatured collagen, we investigated the structure-activity relationship of cyclic collagen-mimetic peptides (cCMPs). Reported cCMP prototypes tend to self-assemble and they must be disassembled just before use. Introducing charge repulsion and a deformation in the peptide backbone structure enabled cCMPs to detect denatured collagen without a pre-treatment for disassembly. Using the optimized cCMP, types I-V collagen were detected by western blotting and denatured collagen fibrils were visualized in a cell culture system.
[kakao](../../index.md) / [com.agoda.kakao](../index.md) / [FirstViewMatcher](index.md) / [matched](.) # matched `var matched: `[`Boolean`](https://kotlinlang.org/api/latest/jvm/stdlib/kotlin/-boolean/index.html)
Product Description An interesting packing puzzle. There is a half-cube frame, some internal pieces with pegs, and a series of plaques with holes. To solve the puzzle, you must arrange the internal pieces in order to fit the constraints of the plaque. This is quite challenging as the plaques can be rotated multiple ways respective to each other. Made in wood and stainless steel by Jean-Claude Constantin. Jean-Claude Constantin lives in Germany, where he designs and manufactures many different wood and metal puzzle, as well as magic tricks. Write your own review * If you're vision impaired or are using a browser that doesn't display images, please email your review to info@puzzlemaster.ca instead of using this form. Your review will be approved by the site admins (to filter inappropriate matter and spam) before appearing on the site.Please only post your message once, it will be received and processed in a timely manner. We make every attempt to post all legitimate reviews submitted, positive or negative. To help ensure your review appears please make it relevant to the product shown above and keep your words family friendly. If you provide an email address (above) you will be notified when your review is processed. Your email address will not be used for any other purpose and you will not be added to any mailing lists. Thank you for sharing your opinions with us and others! Subscribe to our newsletter Receive monthly updates and exclusive offers from Puzzle Master right in your inbox, all for FREE! You will be able to unsubscribe at any time.
Cloning and embryonic expression of Hrsna, a snail family gene of the ascidian Halocynthia roretzi: implication in the origins of mechanisms for mesoderm specification and body axis formation in chordates. snail family genes encode a transcription factor with specific zinc finger motifs. In vertebrates, they are expressed in the entire mesoderm in early embryogenesis and later in the paraxial mesoderm and the tail-bud, suggesting roles in specification and morphogenesis of the paraxial mesoderm. In the present study, a snail family gene Hrsna from a member of the chordates, an ascidian (Halocynthia roretzi), was cloned to obtain an insight into the origin of the mechanisms of mesoderm specification and body axis formation as observed in vertebrates. Expression of Hrsna during ascidian embryogenesis was found to be quite similar to that of vertebrate snail genes. First, before gastrulation, Hrsna was initially expressed in most precursors of mesodermal tissues including the notochord where As-T, the ascidian homolog of brachyury, was expressed. Hrsna expression persisted in the paraxial mesoderm, the mesenchyme and muscle, but not in the notochord precursors. Also, just as vertebrate snail family genes are expressed in the border of the neural plate that develops into dorsal neural tube and neural crest cells, so Hrsna expression was detected in the precursors of lateral and dorsal regions of the neural tube. However, Hrsna expression was not detected in the tip of the tail, unlike in vertebrate counterparts. In the light of the present findings, similarity and dissimilarity of mechanisms governing mesoderm specification and body axis formation between ascidians and vertebrates are discussed.