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Conflict of interest | The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review proce... | PMC10642256 | ||
Publisher’s note | All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or ... | PMC10642256 | ||
Supplementary material | infection, NLV | VIRUS, DISEASE, RECRUITMENT, INFECTION, PROLIFERATIVE | The Supplementary Material for this article can be found online at: Study design overview. Patients were randomized at visit 1 before allogeneic stem cell transplantation between day -28 and -7. Transplant procedure was carried out according to standards of the participating centers. A small fraction of the stem cell g... | PMC10642256 |
References | PMC10642256 | |||
Background | pain, Low back pain | Low back pain is one of the most common disabling pathologies in humanity worldwide. Physical exercises have been used in recent decades to reduce the pain, improve the functionality of the lumbar spine and avoid relapses. The purpose of the study is to analyze the effect of a program based on re-education exercises in... | PMC10483714 | |
Methods | pain | A two-arm, single-blind randomized control trial with 35 primary care patients with chronic nonspecific low back pain. Both groups received a 4-week intervention. Data were collected at baseline and at the end of the intervention. Sixteen patients participated in the intervention group, and 19 patients in the control g... | PMC10483714 | |
Results | disability, pain | For the experimental group, the outcomes of disability and activation of the abdominal transverse muscle decreased significantly (MD -2.9; CI 95% -5.6 to -0.35; η2 = 0.14; p = 0.028) and (MD 2.3; CI 95% 0.91 to 3.67; η2 = 0.25; p = 0.002) respectively, with a large effect size, compared to the control group. There were... | PMC10483714 | |
Conclusion | disability | A 4-week specific program based on re-education exercises of the preactivation of the abdominal transverse muscle is more effective than conventional treatment for reducing disability and increasing the activation of the abdominal transverse muscle measured by VAS scale and PBU. | PMC10483714 | |
Trial registration | Clinicaltrials.gov identifier: NCT03097497. Date of registration: 31/03/2017. | PMC10483714 | ||
Supplementary Information | The online version contains supplementary material available at 10.1186/s12875-023-02140-3. | PMC10483714 | ||
Keywords | PMC10483714 | |||
Background | lumbopelvic instability, CNLBP, LBP, Low back pain | DISEASE | Low back pain (LBP) is one of the most common disabling pathologies worldwide [In Western countries, the societal costs of this disease are estimated to be 1–2% of the gross national product, and between 80 and 90% of the costs are from productivity loss and disability [LBP does not discriminate based on age, but the i... | PMC10483714 |
Methods | PMC10483714 | |||
Aim | CNLBP, disability, pain | This study aimed to analyze the effect of a program based on re-education exercises on the preactivation of the TrA muscle in terms of pain intensity, disability, activation measured with a pressure biofeedback unit (PBU), thickness measured with ultrasound (US), resistance measured with electromyography (EMG) compared... | PMC10483714 | |
Design | neurological deficit, cancer, CNLBP | CANCER, CARDIAC DISEASE, METASTATIC CANCER | A longitudinal, single-blind, randomized controlled trial study was conducted between August 2017 and November 2018. This study was registered on clinicaltrials.gov (NCT03097497) on 31/03/2017 and followed the Consolidated Standards of Reporting Trials statement (CONSORT) recommendations to develop the structure and gu... | PMC10483714 |
Sample size | The sample size calculation was based on the study by Unsgaard-Tøndel et al. [Accepting an alpha risk of 0.05 (95% confidence) and a beta risk of 0.1 (statistical power of 90%), using a two-sided contrast, 17 individuals were necessary in each group (34 patients in total), accepting a patient drop-out rate of 20%. We u... | PMC10483714 | ||
Randomization and blinding | The researchers used a simple randomization technique. An external researcher generated the randomization assignment using a computer random number generator in Excel 2011 (version 14.0.0) and kept the assignments on a specific computer for this study. The group assignments were inaccessible to the rest of the staff. N... | PMC10483714 | ||
Interventions | Richardson | CONTRACTION | The intervention was carried out at the Faculty of Nursing and Physiotherapy of the University of Lleida, Spain. Based on several previous studies, the duration of the intervention was four weeks [The patients assigned to the control group followed the conventional treatment prescribed by their family physician during ... | PMC10483714 |
Outcomes | ’s lumbar spine, thoracolumbar, fatigue, pain | CREST, CONTRACTION, CONTRACTIONS | The intervention lasted for four weeks. All variables were measured pre- and post-test. For all of the variables, whenever possible, the minimal clinically important difference (MCID) to be detected was established. The study’s main variable was pain intensity measured with a VAS scale of 0–10 cm [The PBU was inserted ... | PMC10483714 |
Statistical analysis | SE, disability, pain | The statistical analysis was performed using the statistical program SPSS v22, and the intention-to-treat analysis was performed with an alpha of 0.05. Quantitative variables were described using the mean, standard deviation (SD), standard error (SE), median, and interquartile range.Sociodemographic baseline characteri... | PMC10483714 | |
Results | LBP, Pain | RECRUITMENT | Recruitment took place in different primary care centers of the “Institut Català de la Salut” in Lleida (Spain) from April to August 2017. Of 271 potential subjects, 155 were impossible to contact, and 78 were excluded after the telephone interview. Figure
CONSORT Flow diagram of the studyFinally, 38 patients particip... | PMC10483714 |
Main outcome | SE, pain | The main outcome in this study was pain intensity measured with a 0–10 VAS scale. The measurements were taken pre- and post-test before the start of the intervention and after four weeks (Tables
Results experimental group*Statistically significant difference. SD: Standard Deviation VAS: Visual Analogue Scale. RMQ: Rol... | PMC10483714 | |
Secondary outcomes | abdominal transverse muscle thickness, disability | SECONDARY | There were four secondary outcomes: (i) disability measured with the RMQ, (ii) activation of the transverse abdominal muscle using the pressure biofeedback unit, (iii) abdominal transverse muscle thickness measured with ultrasound, and (iv) resistance of the transverse abdominal muscle measured with electromyography. A... | PMC10483714 |
Disability (RMQ) | disability | The interaction effect between time and treatment on disability was statistically significant (F(1, 33) = 13.64, p < 0.001, η2 = 0.3). There was a significant main effect of the intervention (differences between measurements pre- and post-intervention) on disability (F(1, 33) = 6.9, p = 0.013, η2 = 0.17). For the exper... | PMC10483714 | |
Activation of the Abdominal Transverse Muscle (PBU) | pain | The interaction effect between time and treatment on pain intensity was statistically significant (F(1, 33) = 32.59, p = 0.00, η2 = 0.49). There was a significant main effect of the intervention (differences between measurements pre- and post-intervention) on the activation of the transverse abdominal muscle using the ... | PMC10483714 | |
Abdominal Transverse Muscle Thickness (US) | abdominal transverse muscle thickness | The interaction effect between time and treatment on abdominal transverse muscle thickness was statistically significant (F(1, 33) = 12.12, p = 0.001, η2 = 0.27). For the experimental group, the abdominal transverse muscle thickness measured with US was significantly increased post-test compared to pre-test (MD 0.74; C... | PMC10483714 | |
Resistance of the Abdominal Transverse Muscle (EMG) | The interaction effect between time and treatment on the resistance of the transverse abdominal muscle was not statistically significant (F(1, 33) = 0.58, p = 0.45, η2 = 0.17). There were no statistically significant differences within and between groups (Table | PMC10483714 | ||
Correlation analysis between the Activation of the Abdominal Transverse Muscle (PBU) and pain (VAS), disability (RMQ) and Abdominal Transverse Muscle Thickness (US) | pain | A statistically significant negative correlation was found between TrA activation and pain (r= -0.358, p = 0.035).There was no correlation between TrA activation and disability.A statistically significant correlation was found between TrA activation and TrA thickness (r = 0.474, p = 0.004). | PMC10483714 | |
Discussion | decreased disability, disability, pain | Our findings suggest that a specific program based on re-education exercises on the preactivation of the transverse abdominal muscle significantly reduces disability and increases the activation capacity of the transverse abdominal muscle in the short term compared to a conventional treatment that includes education ab... | PMC10483714 | |
Limitations | The main limitation of this study is the placement of the US. The professionals were adequately instructed in the use of it and where they must place it to perform the measurement, but due to the morphological variability of each patient, the US position could have been slightly modified, which could cause intraobserve... | PMC10483714 | ||
Conclusions | disability | The main conclusion is that a 4-week specific program based on re-education exercises on the preactivation of the transverse abdominal muscle is more effective than conventional treatment for reducing disability and increasing the activation of the transverse abdominal muscle measured by the RMQ and PBU.Additional stud... | PMC10483714 | |
Acknowledgements | We thank all physicians and patients from the Lleida primary care centers, who provided support and helped in the acquisition of data. | PMC10483714 | ||
Authors’ contributions | All authors read and approved the final version of the article. Study conception and design: FRC; FVP; JSG. Drafting the article or revising: FRC; MMA; FVP; CCS; JSG; MGE; OMN. Acquisiton of data: FRC; FVP; OMN; JSG. Analysis and interpretation of data: FRC; FVP; CCS; MGE; OMN. | PMC10483714 | ||
Funding | This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. | PMC10483714 | ||
Data Availability | The datasets generated during the current study are available from the first author on reasonable request. | PMC10483714 | ||
Declarations | PMC10483714 | |||
Competing interests | The authors declare no competing interests. | PMC10483714 | ||
Ethics approval and consent to participate | This study was conducted according to the Declaration of Helsinki [Participants agreed to sign informed consent forms and participated voluntarily without financial rewards.Organic Law 15/1999 on the Protection of Personal Data, of December 13 [ | PMC10483714 | ||
Consent for publication | Written informed consent for participate in the study was obtained for all the participants.Written Informed consent to publish the images was obtained from the volunteer. | PMC10483714 | ||
Abbreviations | Chronic Nonspecific Low Back PainElectromyographyLow back painPressure Biofeedback UnitMaximum RepetitionRoland-Morris QuestionnaireAbdominal transversus muscleVisual Analogic Scale | PMC10483714 | ||
References | PMC10483714 | |||
Background | autism | Significant challenges remain in the early identification of child developmental disabilities in the community. Implementing supports and services early in the life course has been shown to promote positive developmental outcomes for children at high likelihood of developmental disabilities, including autism. As part o... | PMC10416397 | |
Methods | Autism | A qualitative research methodology with semi-structured interviews and thematic inductive analysis underpinned by grounded theory was utilised. All GPs from South Western Sydney (NSW) and Melbourne (Victoria) who participated in the main program (“GP Surveillance for Autism”) were invited to the interview. GPs who prov... | PMC10416397 | |
Results | autism | Twenty-three GPs across the two sites (NSW: n = 11; Victoria: n = 12) agreed to be interviewed; data saturation had reached following this number of participants. Inductive thematic coding and analysis yielded eight major themes and highlighted common enablers such as the role of GPs in early identification and subsequ... | PMC10416397 | |
Conclusions | autism | The study highlighted the need for practice and policy changes, including further training of GPs alongside sufficient time to complete developmental checks and appropriate financial remuneration through a Medicare billing item. Further research is needed on implementation and scale up of a national surveillance progra... | PMC10416397 | |
Supplementary Information | The online version contains supplementary material available at 10.1186/s12875-023-02121-6. | PMC10416397 | ||
Keywords | PMC10416397 | |||
Methods | PMC10416397 | |||
Study context | autism | This article forms one part of the qualitative component of the main program “A multistate trial of an early surveillance program for autism within General Practices in Australia” [ | PMC10416397 | |
Participant recruitment and interviews | A total of 53 GPs across South-West Sydney (NSW; n = 30) and Melbourne (Victoria; n = 23) recruited as part of the main study were invited to participate in this interview. A formal email invitation was sent along with a participation information sheet and consent form to the 53 practices. Twenty-three of 53 (43%) GPs ... | PMC10416397 | ||
Data analysis | MAY | Interviews were conducted with participants between 1st May and 26th June 2021 by research staff (TW, AL, MG and RN). All interviews were audio-recorded, transcribed by professional transcription services, and coded using NVivo12 [
General interview questions for GPs.What barriers did the COVID pandemic and associated ... | PMC10416397 | |
Results | The analysis yielded eight major themes and 23 subthemes across the two groups/pathways. Figure
Comparisons of barriers, enablers and suggestive improvements out of general practitioners’ perspectives between current GP developmental pathway and ASP research pathway | PMC10416397 | ||
Discussion | autism | RECRUITMENT | A number of factors emerged regarding GPs’ perceptions and experiences about feasibility after they had participated and implemented the program’s developmental surveillance assessments with families of children potentially on the autism spectrum. The findings from this study highlighted a number of enablers, barriers,... | PMC10416397 |
Implications for health practice and policy | autistic, Autism Spectrum Disorders, autism | The findings from this study indicate the need for increased awareness about the importance of developmental screening/surveillance, including for autism, amongst primary care clinicians such as GPs. This should focus on providing education and training about developmental milestones in general and early signs of autis... | PMC10416397 | |
Strengths and limitations | autism-specific | There are a number of strengths to this study, including the use of a semi-structured interview guide for a relatively high number of participating GPs. Further, we maintained a high level of interpretive rigour and trustworthiness and quality of the study through an awareness of reflexivity, data auditing and use of q... | PMC10416397 | |
Conclusion | autism | The findings from this qualitative study provides valuable insights into the perceptions and experiences of Australian GPs regarding the contextual enablers and barriers that impact their participation in developmental surveillance programs, and in particular, the potential and beneficial usage of digital screening too... | PMC10416397 | |
Acknowledgements | Autism CRC, Autism | We would like to gratefully acknowledge and thank the GP clinics who participated in this study. The authors acknowledge the financial support of the Cooperative Research Centre for Living with Autism (Autism CRC), established and supported under the Australian Government’s Cooperative Research Centres Program. | PMC10416397 | |
Authors’ contributions | AMD | JB and VE initially conceived the study. TW led this qualitative phase study and specified the methods. TW, MG, RN, FK, and AL conducted and analysed the interviews. An external researcher RI also reviewed and conducted some analysis of these interviews. TW drafted and revised the manuscript with JB, VE, MG, and AM. Th... | PMC10416397 | |
Funding | Autism CRC, Autism | This work was funded through the financial support of the Cooperative Research Centre for Living with Autism (Autism CRC), established and supported under the Australian Government’s Cooperative Research Centres Program. | PMC10416397 | |
Data Availability | All data generated or analysed during this study are included in this published article and its supplementary information files. | PMC10416397 | ||
Declarations | PMC10416397 | |||
Competing interests | The authors declare no competing interests. | PMC10416397 | ||
Ethics approval and consent to participate | This study was approved by the Human Research Ethics Committee of the University of New South Wales Sydney (HC190143), with reciprocal ethics granted by the La Trobe University Human Research Ethics Committee (HC190143). Written informed consent to participate in this study was provided by the participating GPs. All pr... | PMC10416397 | ||
Consent for publication | Not applicable. | PMC10416397 | ||
Provenance and peer review | Not commissioned; externally peer reviewed. | PMC10416397 | ||
Abbreviations | Autism | DISEASE | Autism Surveillance PathwayAges and Stages QuestionnaireAges and Stages Questionnaire-Social and Emotional ScaleCooperative Research Centre for Living with AutismCulturally and Linguistically DiverseCoronavirus Disease 2019cluster Randomised Controlled TrialGeneral PractitionerKey Age and StageLearn The Signs. Act Earl... | PMC10416397 |
References | PMC10416397 | |||
Subject terms | NCT05373030 | ADVERSE REACTIONS | Data on the safety and immunity of a heterologous booster (fourth dose) after three-doses of inactivated SARS-CoV-2 vaccine in Chinese adults are limited. We evaluate the safety and immunogenicity of Ad5-nCoV in a randomized, double-blind, parallel-controlled phase 4 clinical trial in Zhejiang, China (NCT05373030). Par... | PMC10409730 |
Introduction | coronavirus disease 2019 | BREAKTHROUGH INFECTION, CORONAVIRUS DISEASE 2019 | Breakthrough infection cases of coronavirus disease 2019 (COVID-19) are a continuing issue in the clinical arenaThe administration of a fourth vaccine dose (additional booster) was recommended by the WHO for individuals aged ≥60 years, immunocompromised patients, and healthcare personnel after they have received the th... | PMC10409730 |
Results | PMC10409730 | |||
Study participants | MAY | Between May 14 and 27, 2022, 211 volunteers aged 18–80 years who had received three doses of inactivated vaccine (CoronaVac or Covilo) ≥ 6 months earlier were recruited and screened for eligibility for this phase 4 trial. A total of 201 participants, including 120 adults (18–59 years) and 81 older individuals (60–80 ye... | PMC10409730 | |
Factors influencing antibody levels | ADVERSE REACTIONS | The seropositivity and seroconversion results for the BA.4/5 pseudovirus-neutralizing antibody grouped by age (i.e., 18–59 years and 60–80 years), sex, BMI, chronic conditions, and adverse reactions are presented in Table Analysis of factors influencing antibody levels (Omicron BA.4/5)Comparisons were analyzed by Fishe... | PMC10409730 | |
Discussion | infection | ADVERSE EVENTS, INFECTION, VIRUS | Vaccination provides immune-protection against SARS-CoV-2, owing to the induction of neutralizing antibodies and cellular immunity. However, as we are faced with the rapid evolution of SARS-CoV-2 variants worldwide and the virus’s increasing immune escape abilityThe antibody levels following homologous booster of inact... | PMC10409730 |
Methods | PMC10409730 | |||
Study design and participants | anaphylaxis, fever, laboratory-confirmed SARS-CoV-2 infection, neurologic illness, hypertension, diabetes | ADVERSE REACTIONS, RESPIRATORY DISEASE, ANAPHYLAXIS, CARDIOVASCULAR DISEASE, CORONAVIRUS, HYPERTENSION, DISEASE, DIABETES | We performed a single-center, randomized, double-blind, parallel-controlled trial of a fourth vaccine dose with heterologous booster (Ad5-nCoV) or homologous booster (inactivated SARS-CoV-2 vaccine) in a population that had completed a three-dose inactivated SARS-CoV-2 vaccine regime in Hangzhou, Zhejiang Province, Chi... | PMC10409730 |
Vaccines | Trial vaccines included CoronaVac (Vero Cell; Beijing Sinovac Research & Development, Beijing, China) and Covilo (Vero Cell; Beijing Institute of Biological Products Co., Beijing, China), which are inactivated whole virion vaccines to wild-type SARS-CoV-2 with aluminum hydroxide as the adjuvant, administered intramuscu... | PMC10409730 | ||
Randomization and masking | The block randomization method was used with block sizes of 2 and stratified by age group. Eligible participants in each cohort were randomly assigned at a 1:1 ratio to receive Ad5-nCoV or inactivated vaccine. Randomization was done using a sealed enveloped system integrated with the electronic case report forms in the... | PMC10409730 | ||
Procedures | redness, nausea, itching, swelling, fever, cellulitis, muscle ache, fatigue, pain, headache | ADVERSE REACTIONS, ADVERSE EVENTS, CELLULITIS, ADVERSE EVENT, INDURATION, MAY, EVENTS | In May 2022, 200 eligible participants received one dose of Ad5-nCoV or inactivated vaccine via intramuscular injection. The variety of the fourth dose of inactivated vaccine was the same as that used for the pre-received third dose. After the booster vaccination, all participants were monitored for 30 min for any imme... | PMC10409730 |
Outcomes | SARS-CoV-2-specific RBD | ADVERSE REACTIONS, SECONDARY, ADVERSE EVENTS, CHRONIC DISEASES | The primary outcomes were the occurrence of solicited local or systemic adverse reactions and assessments of geometric mean concentration (GMC)/geometric mean titer (GMT), seroconversion/seropositive rates, and geometric mean fold increase (GMFI) of antibodies that bind SARS-CoV-2-specific RBD and pseudovirus-neutraliz... | PMC10409730 |
Statistical analysis | ADVERSE EVENT | The sample size calculation was based on the assumption that heterologous booster immunization with Ad5-nCoV after three-dose priming with inactivated SARS-CoV-2 vaccine would elicit non-inferior and superior concentrations of neutralizing antibodies compared with a homologous booster dose with inactivated SARS-CoV-2 v... | PMC10409730 | |
Supplementary information |
Supplementary InformationPeer Review File | PMC10409730 | ||
Supplementary information | The online version contains supplementary material available at 10.1038/s41467-023-40489-2. | PMC10409730 | ||
Acknowledgements | We thank all the generous volunteer subjects who enrolled in the study. This work was supported by the Key Research and Development Program of Zhejiang Province (2021C03200, J.J., H.L., H.Z.); the Key Program of Health Commission of Zhejiang Province/Science Foundation of National Health Commission (WKJ-ZJ-2221, H.L., ... | PMC10409730 | ||
Author contributions | RECRUITMENT | H.L., J.J., and H.Z. were the principal investigators who designed and performed the research and coordinated the study; N.X., X.H., P.Q., Q.H., Y.L., and J.Y. led and participated in the site work, including the recruitment, follow-up, and data collection; S.W., J.F., L.D., Y.X., S.Z. and B.X. supervised the study; H.... | PMC10409730 | |
Peer review | PMC10409730 | |||
Data availability | The raw data on demographics and clinical status of participants, are protected and not available due to data privacy laws. The processed data are available by specific request to the corresponding author Huakun Lv(hlv@zj.cdc.cn). | PMC10409730 | ||
Competing interests | Y.X., S.Z., and B.X. are employees of CanSino Biologics and contributed to the conceptualization of the study (clinical protocol and electronic case report form design) but did not participate in the analysis or interpretation of the data presented in the manuscript. All other authors declare no competing interests. | PMC10409730 | ||
References | PMC10409730 | |||
Background | denture, edentulous, Denture | Denture adhesives can be useful in improving patients’ satisfaction with complete dentures. However, comparison clinical trials are lacking. The purpose of this randomized clinical trial was to assess the satisfaction of edentulous patients and their oral health impact profile when provided with 3 types of denture adhe... | PMC10731830 | |
Methods | denture, edentulous | Sixty-four completely edentulous patients seeking complete dentures for their first time were randomly divided into 3 groups. Each group received a set of complete dentures, which were adjusted at review appointments until participants reported no complaints. After 1 month of using the dentures, participants rated thei... | PMC10731830 | |
Results | Significantly higher VAS values were detected in all groups and significantly lower values for many OHIP items in addition to total OHIP values were detected in all groups after using the adhesives ( | PMC10731830 | ||
Conclusions | denture adhesives, edentulous | Using denture adhesives for completely edentulous patients resulted in higher patient satisfaction as indicated by higher VAS scores as well as improved quality of life as indicated by lower OHIP-EDENT scores after using the adhesives. These improvements were not dependent on the type of adhesive, except for ease of cl... | PMC10731830 | |
Trial registration | This trial was registered at ClinicalTrials.gov (ID: NCT05496283) on 11/08/2022. | PMC10731830 | ||
Keywords | PMC10731830 | |||
Background | denture, denture adhesives, edentulous | Complete edentulism is one of the major challenges facing the elderly populations. The majority of these patients experience difficulties with different oral functions including chewing, eating, and speaking. These difficulties can profoundly affect their oral health-related quality of life [The retention of complete d... | PMC10731830 | |
Methods | dry dentures, edentulous, Denture, denture adhesives, tooth, denture | This study was designed as a randomized, single-blind, clinical trial. The study was conducted in accordance with the World Medical Declaration of Helsinki and conformed to the Consolidated Standards of Reporting Trials (CONSORT) statement for randomized clinical trials [All participants were completely edentulous pati... | PMC10731830 | |
Results | Seventy-three participants were initially recruited for this study. However, 9 of them didn’t show up for the second review appointment, resulting in a dropout rate of 12%. As a result, 64 participants were eventually included in this study. The sample consisted of 39 men (61%) and 25 women (39%). The age of the partic... | PMC10731830 | ||
Discussion | xerostomia, impaired manual dexterity, candidiasis, edentulous, mandibular dentures, denture stomatitis, denture adhesives, denture | CANDIDIASIS, XEROSTOMIA, DISEASES | This study aimed to investigate the effects of different types of denture adhesives on complete denture patient satisfaction and oral health-related quality of life. The results showed that the use of denture adhesives significantly improved patient satisfaction scores and OHIP scores in all 3 groups, except for the ea... | PMC10731830 |
Conclusions | denture adhesives, edentulous | Within the limitations of this study, the following conclusions can be withdrawn:Using denture adhesives for completely edentulous patients resulted in higher patient satisfaction as indicated by higher VAS scores as well as improved quality of life as indicated by lower OHIP-EDENT scores after using the adhesives.Thes... | PMC10731830 | |
Acknowledgements | Not applicable. | PMC10731830 |
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