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FUNDING INFORMATION
The study was funded by The Research Council of Norway.
PMC10099854
CONFLICT OF INTEREST
The authors declare no conflicts of interest.
PMC10099854
INFORMED CONSENT
Participants were informed with a written consent.
PMC10099854
ACKNOWLEDGEMENT
We thank the subjects for their time, effort, and cooperation during this project. The authors declare no conflicts of interest. The results of this study are presented clearly, honestly, and without fabrication falsification, or inappropriate data manipulation. The study was funded by The Research Council of Norway.
PMC10099854
DATA AVAILABILITY STATEMENT
The data that support the findings of this study are available from the corresponding author upon reasonable request.
PMC10099854
REFERENCES
PMC10099854
Background
mental illness, PLWS, psychiatric, schizophrenia, hopefulness
Hopefulness is a positive orientation or state of mind that can aid in the recovery and treatment of mental illness, as it can have significant impacts on clinical and psychosocial outcomes. As resource-constrained settings work to implement recovery-oriented care, there is a need to better understand hopefulness among...
PMC10339619
Methods
PLWS, hopefulness
This study utilized baseline and immediate post-intervention data collected as part of a randomized controlled trial testing a culturally tailored model of Family Psychoeducation, KUPAA, in Tanzania. The Herth Hope Index was used to measure hopefulness among PLWS (
PMC10339619
Results
PLWS, lower disability
Better family functioning was associated with higher levels of hopefulness in PLWS and their caregivers. Lower levels of stigma, lower symptom severity, and lower disability were associated with higher levels of hopefulness in PLWS. For PLWS and their caregivers, actor effects from the APIM model were less than one (PL...
PMC10339619
Conclusion
PLWS, hopefulness
Hopefulness is important to consider in family or caregiver-based treatments for PLWS because caregiver hopefulness may influence improvements in hopefulness among PLWS over time. Future studies should further explore the longitudinal dyadic relationship of hopefulness for these populations, as hope is a non-pharmacolo...
PMC10339619
Trial registration
Clinical Trials #NCT04013932, July 10, 2019.
PMC10339619
Supplementary Information
The online version contains supplementary material available at 10.1186/s12888-023-04990-8.
PMC10339619
Keywords
PMC10339619
Background
schizophrenia [Mental illness, PLWS, psychiatric, Schizophrenia, schizophrenia, hopefulness
DISORDER, SECONDARY
Schizophrenia is a severe psychiatric disorder that affects 21 million people worldwide [In low- and middle-income countries like Tanzania and high-income countries like the United States, there are high rates of relapse and rehospitalizations for schizophrenia, highlighting the urgent need for accessible, recovery-ori...
PMC10339619
Methods
PMC10339619
Study overview
Psychotic Disorders, ’
All data used in this study were collected as part of the pilot individually randomized group treatment trial titled: “Family Psychoeducation for Adults with Psychotic Disorders in Tanzania” (KUPAA), funded by the National Institute of Mental Health (NIMH) [R34MH106663]. KUPAA is a Swahili word meaning ‘to soar’ and it...
PMC10339619
Study setting
MZRH, psychiatric
The KUPAA study was conducted in Dar es Salaam and Mbeya regions, located in the East African country of Tanzania. The first study site was Muhimbili National Hospital (MNH), which is located in the major urban city of Dar es Salaam. MNH is the national referral hospital with a catchment area of about 4 million people....
PMC10339619
Participants
schizophrenia
DISEASE
A total of 66 dyads composed of individuals living with schizophrenia and their caregivers were included in the study. The study was powered for the primary aim of the clinical trial, which was to assess intervention efficacy, and not for the APIM analysis. All treatment-engaged patient participants had an ICD-10 (Inte...
PMC10339619
Procedures
schizophrenia
SYNDROME, POSITIVE
Baseline data collection took place in September and October of 2019, the intervention was delivered from November 2019 to February 2020, and immediate post-intervention follow-up data collection occurred from March through June of 2020. Written informed consent was obtained from all participants after being screened f...
PMC10339619
Measures
schizophrenia, disability
REGRESSION, SYNDROME, POSITIVE
This study includes measures for PLWS and their caregivers. The World Health Organization’s four-step translation and cultural validation process, namely, forward-translation, back-translation, pre-testing, and finalization with expert consensus, was implemented for all scales in the study [Hopefulness, our dependent v...
PMC10339619
Results
PMC10339619
Participant characteristics
Table Table
PMC10339619
Correlates of hopefulness
REGRESSION
Supplemental Table Results of univariable and multivariable linear regression models estimating mean hopefulness for PLWSTable Results of univariable and multivariable linear regression models estimating mean hopefulness for caregivers
PMC10339619
APIM analysis
The results of the APIM analysis are depicted in Fig. Results of APIM analysis. Time 0 is baseline data collection and time 1 is data collection immediately post-interventionIn an APIM model, the joint effect, or the additive effect of both actor and partner baseline HHI score on follow-up actor HHI score, differs depe...
PMC10339619
Discussion
mental illness, illness, PLWS [A, cancer, PLWS, disability, hopefulness
CANCER, RECRUITMENT
The current study examined the independent and dyadic associations between hopefulness and selected predictors within the PLWS-caregiver relationship. Hopefulness in our study population exhibits interdependence meaning dyad partners influence one another’s level of hope over time. To the best of our knowledge, there i...
PMC10339619
Conclusion
schizophrenia, PLWS hopefulness
The results of our study suggest that hopefulness may be important to consider in PLWS treatment regimens as caregiver hopefulness is associated with improvements in PLWS hopefulness over time. Dyads of this nature are complex, and members are continuously influencing each other’s outcomes. Neither schizophrenia nor ho...
PMC10339619
Acknowledgements
We thank our colleagues at the Muhimbili National Hospital and Mbeya Zonal Referral Hospital in Tanzania for supporting this clinical trial. We are also incredibly grateful to the affected individuals that gave their time and energy to our study.
PMC10339619
Authors’ contributions
AM wrote the first draft of the manuscript. AM, JRE, and JNB contributed to the design, implementation, and analysis of the study and edited the first draft. All authors revised drafts and approved the final manuscript.
PMC10339619
Funding
Funding was received from the National Institute of Mental Health (NIMH; award 5R34MH106663).
PMC10339619
Availability of data and materials
SECONDARY
The dataset generated and analyzed during the current study is not publicly available per IRB requirements, but it is available from the senior author (JRE) on reasonable request, with permission from study PIs, and with IRB approval for secondary analyses to maintain confidentiality.
PMC10339619
Declarations
PMC10339619
Consent for publication
Not applicable.
PMC10339619
Competing interests
None.
PMC10339619
References
PMC10339619
1. Introduction
Ten percent of Americans are food-insecure. Few known studies have accessed college food insecurity via random sampling. An online cross-sectional survey (Food insecurity is a global health concern. A total of 13.5 million Americans (10.2%) have experienced food insecurity at some point within the last year [The USDA d...
PMC10005036
2. Materials and Methods
PMC10005036
2.1. Sample
A self-administered online survey via Qualtrics was sent to a simple random sample of 5000 currently enrolled University of Florida (UF) undergraduate students. The total undergraduate population at UF was 35,043 (female: 19,355 (55.2%), male: 15,688 (44.8%)). A request was made to the UF Office of Institutional Planni...
PMC10005036
2.2. Measure of Food Insecurity
The six-item food security scale is an instrument created by the USDA developed to determine the level of food security of individuals [There are six-items from the USDA Food Security Short Form which measure food insecurity experienced within the last 12 months. These six items are:“In the last 12 months, the food tha...
PMC10005036
2.3. Measure of Government Assistance
Respondents were asked “if their family ever obtained government assistance during childhood (government housing, free/reduced lunch in school, SNAP, Women, Infants, and Children (WIC), and food banks)”. Respondents had the option to “choose all that apply” from the listed options.
PMC10005036
2.4. Measures of Food Shortage Contacts
For the last item, respondents were asked to “choose all that apply” as to whether they felt comfortable discussing with a parent, roommate, counseling and wellness personnel, advisor/mentor, resident assistant, or professor if they were running short on food.
PMC10005036
2.5. Data Analysis
The data for this study were analyzed using JMP Pro 12 (SAS Institute Inc., Cary, NC, USA, 1989–2021) software. Descriptive statistical analyses were used to provide group percentages and compare differences among the individual variables. Sociodemographic characteristics that were measured include: current college cla...
PMC10005036
3. Results
PMC10005036
3.1. Sample Characteristics
The mean age for college students was 20.77 ± 3.43. Most (78.1%,
PMC10005036
3.1.1. Food Insecurity
Students responded to a total of six items to measure their individual level of food insecurity. Out of 1087 total responses to all items, 36.1% (Food insecurity differences were found based on race. Most of the students that were food-insecure were non-white (59.6%,
PMC10005036
3.1.2. Food Insecurity and Food Bank Usage
Over half of all college students (56.5%,
PMC10005036
3.1.3. Campus Meal Plan
Most students did not have a campus meal plan (52.3%,
PMC10005036
3.1.4. GPA
The average GPA was 3.45 ± 0.39 for all participants. The mean GPA of all food-insecure students was 3.36 ± 0.42. Significant differences in GPA were found based on food security status (t(1039) = 34.78;
PMC10005036
3.1.5. Student Employment and Volunteer Activities
Most students (53.7%, College students reported that they participated in volunteer activities for on average 8.64 ± 6.63 h per week. Food-insecure students were significantly more likely to participate in volunteer activities compared to food-secure students (9.42 ± 6.96 vs. 7.58 ± 6.03; t(719) = 13.73;
PMC10005036
3.1.6. Student Financial Aid and Debt
Most students were currently receiving financial aid (65.1%,
PMC10005036
3.1.7. Marital Status
Most students were single (97.4%,
PMC10005036
3.1.8. US Citizenship
Most students were born in the US (86.0%,
PMC10005036
3.1.9. First-Generation Student
Most (67.3%,
PMC10005036
3.1.10. Online/Distance Education
Most students were not in an online/distance education program (94.9%,
PMC10005036
3.1.11. Current Residence
Most students lived off-campus (74.2%,
PMC10005036
3.1.12. Fraternity/Sorority
Most students were not members of a fraternity/sorority (80.9%,
PMC10005036
3.2. Food Insecurity and Government Assistance
Participants were asked to “choose all that apply” based on five government assistance programs participated in during childhood. Most students never lived in government housing (94.8%,
PMC10005036
3.3. Food Insecurity and Food Shortage Contacts
Participants were asked to “choose all that apply” based on who they were comfortable telling that they were short on food. Most students reported they were comfortable telling a parent (79.8%,
PMC10005036
4. Discussion
PMC10005036
4.1. Prevalence of Food Insecurity
In the current study, 36.1% of college students were found to be food-insecure. The prevalence of food-insecure college students at this university was nearly four times greater compared to the entire state of Florida (36.1% vs. 9.9%), and three times greater than the food-insecure population in Alachua County, Florida...
PMC10005036
4.2. Profile of a Food-Insecure College Student
The current study found many differences in the demographics of food-insecure students compared to the total sample. Food-insecure college students in this study were significantly more likely to be non-white, on financial aid, employed, with lower GPAs, and first-generation college students compared to those that were...
PMC10005036
4.2.1. Employment among Food-Insecure College Students
Employment status and hours volunteered per week were found to have significant differences in food security status in the current study. Similarly, one study found that college students were more likely to be food-insecure if they were employed while in school and averaged 18 h of work per week [
PMC10005036
4.2.2. Off-Campus Food-Insecure College Students’ Food Access
Off-campus students represented most of the college students within the study. Off-campus college students represented three times as many of the food-insecure students within the study compared to on-campus students (75% vs. 25%). Off-campus students could possibly experience food insecurity due to a number of factors...
PMC10005036
4.2.3. Food-Insecure Students’ Food Shortage Contacts
Being a college student often comes with the notion of the “silent struggle”, representing the stereotypical college student that might be short on food or barely surviving on limited options [One Canadian study of food-insecure college students found that nearly 76% received food from a relative or went to a relative’...
PMC10005036
Author Contributions
Conceptualization, C.H.II and D.C.S.J.; methodology, C.H.II; software, D.C.S.J.; validation, C.H.II and D.C.S.J.; formal analysis, C.H.II; investigation, C.H.II; resources, D.C.S.J.; data curation, C.H.II; writing—original draft preparation, C.H.II, D.C.S.J. and A.B.; writing—review and editing, C.H.II, D.C.S.J. and A....
PMC10005036
Institutional Review Board Statement
The study was conducted in accordance with the Declaration of Helsinki and approved by the Institutional Review Board (or Ethics Committee) of the University of Florida (IRB#201601763, approved 15 September 2016).
PMC10005036
Informed Consent Statement
Informed consent was obtained from all subjects involved in the study.
PMC10005036
Data Availability Statement
The data presented in this study are available upon request from the corresponding author. The data are not publicly available due to FERPA regulations.
PMC10005036
Conflicts of Interest
The authors declare no conflict of interest.
PMC10005036
References
Student responses to the USDA Food Security Short Form.Chi-square analysis of childhood access to government assistance based on food security status of undergraduate college students.* Chi-square analysis of contacts for college students if experiencing a food shortage, by food security status.*
PMC10005036
Introduction
ambiguous social situations, depression, anxiety disorder, anxiety
DISEASE
According to the 2016 Psychological Disease Dynamics Survey released by the Ministry of Health and Welfare of Korea, the demographic distribution of the annual prevalence rate of social anxiety disorder in 2016 was 1.0% in the age group of 18–29 years, and this figure is about twice as high as the below 0.5% for other ...
PMC10653471
Method
PMC10653471
Participants
A total of 114 undergraduate and graduate students completed an online screening survey using the Center for Epidemiological Studies-Depression(CES-D), Social Avoidance Distress Scale (SADS), and Brief version of Fear of Negative Evaluation Scale (B-FNE). Participants who scored under 16 points on the CES-D, < 99 point...
PMC10653471
Questionnaires
PMC10653471
Center for Epidemiological Studies-Depression (CES-D)
The CES-D [
PMC10653471
Social Avoidance and Distress Scale (SADS)
The SADS [
PMC10653471
Brief Version of Fear of Negative Evaluation Scale (B-FNE)
The B-FNE [
PMC10653471
Visual Analogue Scale (VAS)
pain
To assess participants’ state mood, they were asked to rate their mood before and after the training and the first filler task. The VAS was used as a self-report measure of current emotions and pain. The VAS is a simple tool that allows individuals to rate their subjective state [
PMC10653471
Six-item short version of the state-trait anxiety inventory (STAI-6)
STAI-6 [
PMC10653471
Training
PMC10653471
Imagery training
Imagery practice of approximately 10 minutes was conducted for the participants before the CBM-I training. Imagery practice was based on Oxford Imagery Generation (OxIGen) used by Blackwell and colleagues [
PMC10653471
Cognitive Bias Modification-Interpretation (CBM-I)
CBM-I was structured on interpretation training with imagery used by previous studies [Salemink, Kindt [
PMC10653471
Test phase
PMC10653471
Similarity Rating Task (SRT)
The SRT was used in this study to assess the participants’ interpretation bias after CBM training. The procedure and format of the SRT were based on the previous studies [<Presentation of liberal arts class>You give a presentation in a liberal arts class.After the presentation, some people ask you questions.As you answ...
PMC10653471
Free recall task
To assess memory bias related to the scenarios, the free recall task used by Joormann, Waugh [The coding format used by Joormann, Waugh [
PMC10653471
Past recollection task
MACLEOD
To examine whether there was a bias in not only recalling the scenario but also a memory from the participant’s actual past, the future thinking task used by MacLeod and Byrne [
PMC10653471
Procedure
SECONDARY
The present study was approved by the authors’ University’s Institutional Review Board (KWNUIRB-2017-05-006-003). Participants were recruited via internet communities and university bulletin boards. When the participants contacted the researchers, they received a preliminary screening survey link to complete. If the pa...
PMC10653471
Flowchart of the experiment for positive and negative CBM-I.
Participants were randomly assigned to either a positive CBM-I group or a negative CBM-I group. They completed the VAS (happiness, sadness) for baseline measurement and participated in approximately 10 min of imagery training, followed by CBM-I training. Subsequently, the VAS and STAI-6 was completed. To minimize the e...
PMC10653471
Result
PMC10653471
General characteristics of groups and test of homogeneity
To investigate between-group differences in demographic variables and pre-test measurements, independent samples
PMC10653471
The effects of CBM-I on state mood
’ mood
To examine the effects of CBM-I on participants’ mood states, we conducted a 2 (group: positive CBM-I, negative CBM-I) × 2 (time: Pre, Post) × 2 (valence: happiness, sadness) repeated ANOVA (dependent variables: pre- and post-levels of sadness and happiness). Analyses revealed the three-way interaction of group, time, ...
PMC10653471
The effects of CBM-I on state anxiety
anxiety
To examine the effects of CBM-I on participants’ state anxiety, we conducted a 2 (group: positive CBM-I, negative CBM-I) × 2 (time: Pre, Post) repeated ANOVA (dependent variables: pre-post state anxiety measured with STAI-6). Results revealed that there were the main effect of group,
PMC10653471
The effects of CBM-I on interpretation bias
To investigate the effects of CBM-I on interpretation bias (dependent variables: target positive, target negative, foil positive, foil negative), a generalized linear mixed model (GLMM) was conducted to investigate the interactions between group (positive CBM-I, negative CBM-I), sentence type (target, foil) and valence...
PMC10653471
Mean and standard deviation in each group for recognition task, free recall task, and past recollection task.
PMC10653471
GLMM for Effects of CBM-I training on interpretation bias.
SE
Group was coded as 1 for positive-CBM -I and 2 for negative CBM-I; The Sentence was coded as 1 for Target sentence and 2 for Foil sentence; Valence was coded as 1 for positive and 2 for negative. SE = Standard Error.
PMC10653471
The effects of CBM-I on memory bias
PMC10653471
Free recall task
A generalized linear mixed models (GLMMs) were conducted to investigate whether CBM-I training affected the participants’ memory bias (see the results of the GLMM in
PMC10653471
Mean of neutral, positive, and negative memory intrusion made by each training group during the recall task.
Error bar represent 1
PMC10653471
GLMM for Effects of CBM-I training on free recall and past recollection.
SE
Group was coded as 1 for positive-CBM -I and 2 for negative CBM-I; Valence was coded as 1 for positive, 0 for neutral, and -1 for negative. SE = Standard Error.For content, a significant two-way interaction between group and content valence was observed, The groups also differed in the number of errors: the negative gr...
PMC10653471
Past recollection task
In addition to the memory bias for SRT scenarios, we investigated whether memory bias could be observed in past memories. A generalized linear mixed models(GLMMs) were conducted to investigate whether CBM-I training influenced the participants’ past memories. Specifically, a two-way interaction between group (positive ...
PMC10653471
Discussion
anxiety
The main purpose of the present study was to examine whether experimentally induced interpretation bias would affect biases in memory in Korean samples. In doing this, the present study used CBM scenarios that were auditory-specific and with a focus on social anxiety symptoms. The main results showed that interpretatio...
PMC10653471