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1,328 | Strategies for enhancing compliance in the dialysis elderly.
Noncompliance must be viewed as a symptom of another problem or problems.
Treatment plans should be developed based on an individualized assessment of the patient's physiologic functioning and psychosocial situation.
It must be determined whether the patie... | 11 |
2,536 | Treating diabetes in the elderly. What are the special considerations?
Management of diabetes in elderly patients generally follows the same lines as in younger patients; that is, improvement of blood glucose status with diet, oral hypoglycemic, and insulin therapy as required.
Older patients are more fragile, howeve... | 18 |
1,334 | Spontaneous resolution of congenital nephrotic syndrome in a neonate
An infant with congenital nephrotic syndrome recovered spontaneously and completely by the age of 11 days and had remained well at the age of 1 year.
This reinforces the view that reversible congenital nephrotic syndrome does occur and that it is n... | 11 |
711 | Unconjugated bilirubin and cholesterol gallstone formation.
Cholesterol gallstones usually have small amounts of pigment at their centers and often have diffuse pigmentation or pigmented layers alternating with cholesterol layers and/or pigmented rims associated with calcium carbonate (eggshell calcification).
The pi... | 5 |
1,770 | Time course of cellular enzyme release in dog heart injury.
The transport time of enzyme from heart to plasma was studied in two experimental models.
First, the enzyme alanine aminotransferase was slowly infused into the left ventricular wall in open-chest dogs.
The half-life for the washout of alanine aminotransfer... | 13 |
370 | Total pelvic exenteration with simultaneous bowel and urinary reconstruction.
The technique of total pelvic exenteration with simultaneous bowel and urinary reconstruction is described as a surgical option for the management of pelvic sarcoma in adults and for highly selected patients with other types of advanced pelv... | 3 |
152 | Immunization of owl monkeys with a combination of Plasmodium falciparum asexual blood-stage synthetic peptide antigens.
A mixture of 3 synthetic peptides (35.1, 55.1, and 83.1) corresponding to portions of the 35 kDa, 55 kDa, and 83 kDa proteins from the asexual blood stages of Plasmodium falciparum and a polymer of a... | 2 |
2,070 | Apical hypertrophic cardiomyopathy in a non-Oriental man.
Japanese investigators first described apical HCM in 2.9% of patients who had diagnostic left ventricular catheterization for suspected ischemic heart disease or cardiomyopathy.
This entity was initially thought to be limited to individuals of Asian origin and... | 13 |
87 | Initial evaluation of human monoclonal anti-lipid A antibody (HA-1A) in patients with sepsis syndrome.
HA-1A, a human monoclonal immunoglobulin M antibody that binds specifically to the lipid A domain of endotoxin, was administered to septic patients to evaluate the safety, pharmacokinetics, and immunogenicity of the ... | 0 |
632 | Cross-sectional radiography for implant site assessment.
An accurate tomographic technique is described for acquisition of optimal cross-sectional images of implant sites before implant surgery.
The described technique is applicable to tomographic systems equipped with a cephalometric head positioner.
This cross-sec... | 4 |
2,221 | Osmiophilic deposits in cytosomes in Hallervorden-Spatz syndrome.
A young child with Hallervorden-Spatz syndrome is presented.
She was well until 8 years of age when she lost interest in activities and her school performance declined.
At age 11 years, she began having episodes of blepharospasm, accompanied by bilate... | 15 |
3,008 | Different tumor-derived p53 mutants exhibit distinct biological activities.
In its wild-type form, the protein p53 can interfere with neoplastic processes.
Tumor-derived cells often express mutant p53.
Full-length mutant forms of p53 isolated so far from transformed mouse cells exhibit three common properties in vit... | 22 |
2,138 | Incubation of platelet concentrates before transfusion does not improve posttransfusion recovery.
Incubation of stored platelet concentrates (PCs) at 37 degrees C for 1 hour has been reported to result in a better morphology score and improved platelet recovery.
A study was conducted in adult patients with leukemia t... | 14 |
1,744 | Responses of cytosolic free calcium to ADP in platelets of spontaneously hypertensive rats.
Abnormalities of Ca2+ handling have been reported in patients with essential hypertension and in spontaneously hypertensive rats (SHR).
In this study, responses of cytosolic Ca2+ to ADP in platelets of SHR were examined.
Four... | 13 |
828 | Xipamide disposition in liver cirrhosis.
The pharmacokinetics of the sulfonamide-type diuretic xipamide was studied in patients with liver cirrhosis and ascites and compared with healthy control subjects.
After oral administration of 40 mg xipamide, the diuretic was rapidly distributed in the blood and the ascites.
... | 5 |
1,622 | Prostaglandins, the kidney, and hypertension
Prostaglandins are part of the family of oxygenated metabolites of arachidonic acid known collectively as eicosanoids.
While they are formed, act, and are inactivated locally and rarely circulate in plasma, they can affect blood flow in some tissues and so might contribut... | 13 |
3,237 | Vitamin B6 in the treatment of the premenstrual syndrome--a review [published erratum appears in Br J Obstet Gynaecol 1991 Mar;98(3):329-30]
A search of the literature yielded 12 controlled trials on vitamin B6 in the treatment of the premenstrual syndrome.
These are discussed with emphasis on methodological aspects... | 22 |
2,243 | DNA content and Ks8.12 binding of the psoriatic lesion during treatment with the vitamin D3 analogue MC903 and betamethasone.
Twenty patients with psoriasis were treated with the vitamin D3 analogue MC903 and betamethasone ointment in a double-blind trial with a left-right comparison.
In addition to the clinical seve... | 16 |
735 | CT diagnosis of acquired small bowel volvulus.
Small-bowel volvulus is an uncommon but important cause of small-bowel obstruction and often results in ischemia or infarction.
Clinical examination and plain film radiography may be nondiagnostic, leading to delay in surgical intervention with subsequent increase in mor... | 5 |
2,338 | Digital imaging techniques in dermatology.
Digital imaging is a versatile technique that has been infrequently used in dermatology to record visual images.
We have used this technology for 10 patients to follow cutaneous lesions, including alopecia mucinosa, psoriasis, and dysplastic nevi.
The setup included a perso... | 16 |
242 | Clinical significance of colonic fermentation.
Recent evidence of the potential benefits of short chain fatty acids has prompted renewed interest in the area of human colonic fermentation.
This paper reviews the clinical and metabolic consequences of colonic fermentation.
| 3 |
1,354 | Treatment of testicular cancer: a new and improved model.
Testicular cancer has become a model for a curable neoplasm.
Prior to the advent of cisplatin combination chemotherapy, standard chemotherapy consisted of dactinomycin, alone or in combination with chlorambucil and methotrexate.
Disseminated germ cell tumors ... | 11 |
1,110 | Facial bone fracture associated with carotid-cavernous sinus fistula.
Out of 989 cases of facial bone fracture, ten patients had carotid-cavernous sinus fistulas (1.01%).
Their ages ranged from 25 to 48 years.
Seven were male and three female.
Two of the ten patients had lower third, three patients had middle third... | 9 |
394 | The human immunodeficiency virus type 2 vpr gene is essential for productive infection of human macrophages.
The human immunodeficiency virus (HIV) genetic determinant(s) responsible for tropism in human T cells or macrophages are not well defined.
We studied the role of the HIV type 2 (HIV-2) nef and vpr genes in vi... | 3 |
2,202 | Use of a palatal stabilizing device in prevention of palatal grooves in premature infants.
A prospective, randomized study using an acrylic palatal stabilizing device (PSD) was conducted to evaluate the effectiveness of this device in preventing disruptions in palatal architecture.
A total of 26 premature infants wit... | 15 |
3,166 | Fatigue.
Fatigue is a pervasive, protective phenomenon affecting the totality of the individual.
Assessment and management involve a wide range of activities to address the total human being's physical, psychological, cognitive, and spiritual dimensions.
When elimination or neutralization of the effect of an anteced... | 22 |
509 | Late development of a squamous carcinoma in a reconstructed pharynx.
We report a case in which a squamous cell carcinoma was found to have arisen from a delto-pectoral skin flap used in pharyngeal reconstruction.
The flap had been forming a neo-pharynx for 24 years.
No other signs of recurrent disease had developed ... | 3 |
1,265 | Unilateral mydriasis caused by transdermal scopolamine.
Contamination of the eye after handling of a transdermal scopolamine patch may cause accidental mydriasis.
A simple office test is discussed to identify this pharmacologic blockade and thereby avoid an extensive neurologic workup.
| 10 |
2,715 | HTLV-I sequences are not detected in peripheral blood genomic DNA or in brain cDNA of multiple sclerosis patients.
Human T-cell lymphotropic virus (HTLV-I) was recently reported to be etiologically associated with multiple sclerosis (MS).
Genomic DNA from peripheral blood lymphocytes and brain plaques of patients wit... | 19 |
3,143 | Mitral valve replacement in the first year of life.
From 1973 through 1987 25 patients underwent mitral valve replacement in the first year of life for mitral stenosis and mitral regurgitation.
The patients with mitral stenosis included two with mitral arcade, two with supravalvular mitral stenosis with hypoplastic m... | 22 |
2,741 | Secondary total hip replacement after fractures of the femoral neck.
We studied the rate of revision in 84 consecutive total hip replacements performed for failed osteosynthesis of femoral neck fractures and compared it with that for primary arthroplasty for osteoarthritis.
The age and sex adjusted risk of prosthetic... | 20 |
345 | Adjuvant cyclophosphamide, methotrexate, and fluorouracil in patients with axillary node-positive breast cancer: an update of the Guy's/Manchester trial.
Between 1976 and 1985, 391 patients (202 premenopausal, 189 postmenopausal) with operable breast cancer and positive axillary lymph nodes were randomized after total... | 3 |
3,126 | Isolation of a novel tumor protein that induces resistance to natural killer cell lysis.
The human metastatic tumor cell line CAP-2, produces a soluble factor that induces resistance to NK lysis of K-562 susceptible leukemia cell line, and does not inhibit the cytotoxic capacity of effector cells.
The use of sequenti... | 22 |
9 | Itraconazole in common dermatophyte infections of the skin: fixed treatment schedules.
Itraconazole is an effective medication against the most common dermatophytoses.
It has been shown to be more active than griseofulvin and ketoconazole.
Ease of use, affinity for keratinized tissues, lack of toxicity, continued ac... | 0 |
434 | Localization and surgical treatment of occult insulinomas.
Management of patients with biochemical evidence of insulinoma and negative preoperative imaging studies (occult) tumors is controversial, varying from primarily medical management to aggressive, blind nearly total pancreatectomy to extirpate the tumor.
Since... | 3 |
2,286 | Persistent melanocytic lesions associated with cosmetic tanning bed use: "sunbed lentigines".
A patient with persistent melanocytic lesions after tanning bed use is described.
A review of the literature provides two additional examples of similar clinical and histologic presentations after UVA exposure without psoral... | 16 |
1,532 | Aggressive evaluation for atypical squamous cells in Papanicolaou smears.
A retrospective study was done on women who had atypical Papanicolaou smears and were referred for immediate colposcopy.
The smears were obtained during January 1985 to March 1989 at Edwards Air Force Base, California.
Excluded from the evalua... | 12 |
201 | Comparison of methods for checking surgical margins.
Surgical margins of a cutaneous neoplasm can be evaluated by various combinations of three major types of sections: vertical (perpendicular), horizontal (parallel), and oblique (Mohs method).
Vertical sections may run transversely through tumor (breadloaf method), ... | 3 |
833 | Incidence and prevalence of ulcerative colitis in the upper Galilee, Northern Israel, 1967-1986.
An epidemiological study of ulcerative colitis was performed in the Upper Galilee, Israel, over a 20-yr period (1967-1986).
The average annual incidence of ulcerative colitis was 2.23 per 100,000 population, and the preva... | 5 |
2,451 | Obesity and iron status in menstruating women.
The relationship between iron stores and obesity in menstruating women was studied in 20 obese and 20 nonobese women matched for age and contraception.
Although no difference was observed in serum iron or total-iron-binding capacity, the obese group showed significantly ... | 17 |
1,602 | Effects of benazepril and metoprolol OROS alone and in combination on myocardial ischemia in patients with chronic stable angina
The efficacy of benazepril, metoprolol OROS and their combination was evaluated in 29 patients (42 to 74 years of age) with chronic stable angina and documented coronary artery disease in a... | 13 |
1,364 | Burkitt's lymphoma of the testicle: report of 2 cases occurring in elderly patients.
Burkitt's lymphoma is rare in patients older than 50 years and almost never presents as a testicular tumor.
We report 2 cases of primary Burkitt's lymphoma of the testicle in men 68 and 79 years old.
In 1 man the extragonadal tumor ... | 11 |
3,026 | Thyroid antibodies as a risk factor for Down syndrome and other trisomies.
To test whether the presence of thyroid antibodies in a parent is a risk factor for meiotic nondisjunction, we measured the levels of thyroid antibodies in serum samples drawn during early pregnancy from 101 gravidas who delivered a child with ... | 22 |
178 | Prognostic implication of ecto-5'-nucleotidase activity in acute lymphoblastic leukemia.
Ecto-5'-nucleotidase (5'-N) activity was determined in 191 patients (71 children and 120 adults) with acute leukemia.
Elevated values for 5'-N were registered in common acute lymphoblastic leukemia (ALL), but blast cells of T-cel... | 3 |
2,306 | Experimental models for psoriasis.
Evidence suggests that inherent in skin of psoriatic subjects are cells, architectural structures, and/or mediators, which are, at a minimum, responsible for its hyperproliferative epidermis.
An objective of our laboratory has been to establish an in vitro definition of this inheren... | 16 |
1,047 | Beneficial effect of 1,3-butanediol on cerebral energy metabolism and edema following brain embolization in rats.
We assessed the effect of 1,3-butanediol on cerebral energy metabolism and edema after inducing multifocal brain infarcts in 108 rats by the intracarotid injection of 50-microns carbonized microspheres.
A... | 9 |
2,262 | Surgical management of palmar hyperhidrosis.
Hyperhidrosis is an idiopathic pathologic condition characterized by excessive sweating beyond that required to cool the body.
Disturbance of the central nervous system, endocrine system, or obesity has been associated with this condition.
Patients have a history of sever... | 16 |
2,896 | The hippocampus and parahippocampus in schizophrenia, suicide, and control brains [published erratum appears in Arch Gen Psychiatry 1991 May;48(5):422]
Recent postmortem studies in schizophrenia have shown abnormalities in medial temporal lobe structures, including the hippocampus and parahippocampus.
We tried to rep... | 20 |
2,088 | The real impact of mechanical bridge strategy in patients with severe acute infarction.
Results obtained in the past 3 years in patients referred with acute myocardial infarction (AMI) and cardiogenic shock for a mechanical bridge to urgent transplantation permit one to assess the real impact of the present strategy i... | 13 |
3,342 | Total perinatal wastage. A clarification of priorities.
The pregnancy outcome of 16,971 women carrying 17,352 living fetuses after 16 weeks gestation was studied.
As well as recording perinatal deaths, all losses before 28 weeks and up to one year after delivery were recorded to give a total perinatal wastage rate of... | 22 |
2,097 | ECMO assisted angioplasty for cardiomyopathy patients with unstable angina.
Patients who are otherwise unsuitable candidates for coronary bypass surgery or standard coronary angioplasty (PTCA) may be successfully treated with PTCA during ECMO.
Five patients (3 men, 2 women), with a mean age of 57 years, are reported ... | 13 |
3,197 | Localization of the human angiogenin gene to chromosome band 14q11, proximal to the T cell receptor alpha/delta locus.
The gene encoding angiogenin, a potent inducer of blood vessel formation, has been localized within the human genome.
It is present as a single copy per haploid genome and is located on chromosome 14... | 22 |
1,970 | Differentiation of ventricular tachyarrhythmias.
Implantable devices capable of several modes of therapy will require differentiation of various ventricular tachyarrhythmias.
Three methods of arrhythmia analysis, magnitude-squared coherence, ventricular rate, and irregularity of cycle length were performed for 45 epi... | 13 |
2,649 | Cytomegalovirus infection in children with AIDS.
Data for 38 children perinatally exposed to human immunodeficiency virus (HIV) were evaluated to determine the impact of cytomegalovirus (CMV) infection on the course of perinatally acquired HIV infection.
Thirteen children belonged to the P0 (indeterminate) group, one... | 19 |
1,029 | Bilateral semicircular canal aplasia with near-normal cochlear development. Two case reports.
Congenital malformations of the vestibular labyrinth (pars superior) are rare.
We present two patients with computed tomographic findings of bilateral semicircular canal aplasia with normal or near-normal cochleas.
Initial ... | 8 |
2,792 | Is arterial proximity a valid indication for arteriography in penetrating extremity trauma? A prospective analysis.
Three hundred seventy-three patients with a penetrating extremity injury were studied to assess the yield of arteriography.
Patients underwent arteriography if any of the following was present: bruit, h... | 20 |
1,003 | Effect of vitamin C on histamine bronchial responsiveness of patients with allergic rhinitis.
The effect of acute oral administration of 2 g vitamin C on bronchial responsiveness to inhaled histamine in 16 patients with allergic rhinitis was compared with placebo on two consecutive days in a double-blind, crossover de... | 8 |
526 | Posterior mediastinal teratoma with abdominal extension.
Posterior mediastinal benign teratomas are uncommon neoplasms in infancy; nine cases have been reported so far.
A one month old baby was found to have a benign posterior mediastinal teratoma infiltrating the lower oesophagus from the level of the carina through... | 3 |
2,868 | The acute effects of alcohol on the blood pressure of young, normotensive men.
Alcohol's acute effects on arterial blood pressure (BP) were examined.
To separate the effects of alcohol on BP from those of fluid volume and expectancy, normotensive men were divided into three groups.
The alcohol group received 1.0 ml ... | 20 |
3,355 | En bloc transplantation of kidneys from donors weighing less than 15 kg. into adult recipients.
En bloc transplantation of kidneys from donors who weighed less than 15 kg.
into 20 adult patients is described.
Intraperitonealization of the medial kidney allowed adequate renal positioning and growth.
Graft venous thr... | 22 |
2,582 | Dust mite assays in clinical allergy practice: mite antigen exposures among skin test positive patients in Kansas.
We have attempted to determine whether sensitive monoclonal antibody assays for Dermatophagoides mite antigens Der p I and Der f I can be carried out in a private clinical allergy practice laboratory, to ... | 19 |
2,151 | Hypergammaglobulinemic purpura of Waldenstrom.
Hypergammaglobulinemic purpura of Waldenstrom is characterized by hypergammaglobulinemia, recurring purpura, an elevated erythrocyte sedimentation rate, and the presence of rheumatoid factor indicative of circulating immune complexes.
There is a significant association w... | 14 |
2,902 | Pediatric penetrating head and neck trauma.
Penetrating head and neck trauma in children causes uncommon and potentially life-threatening injuries.
We reviewed the charts of 21 patients who sustained penetrating injuries to the face or upper neck.
Seventeen males and 4 females, aged 32 weeks' gestation to 19 years (... | 20 |
495 | Melanoma and soft tissue sarcoma in seven patients.
Seven patients with both melanoma and sarcoma were seen at the Dana Farber Cancer Institute (Boston, MA) over a 4-year period.
Three had additional malignant neoplasms; one of these patients also had the hereditary cutaneous malignant melanoma, dysplastic nevus synd... | 3 |
2,918 | Endotracheal tube cuff pressure assessment: pitfalls of finger estimation and need for objective measurement.
Estimation of endotracheal (ET) cuff pressure by finger palpation is one of the methods currently used in the clinical setting.
We compared the accuracy of this method with instrumental intracuff pressure mea... | 20 |
173 | Treatment of advanced squamous cell carcinoma of the skin with cisplatin, 5-fluorouracil, and bleomycin.
The authors treated 14 patients with advanced squamous cell carcinoma (SCC) of the skin or lip with one to four cycles of combination chemotherapy consisting of cisplatin by bolus injection, and 5-fluorouracil (5-F... | 3 |
620 | Spondyloepiphyseal dysplasia of Maroteaux.
The cases of four patients who had an unusual clinical entity of disproportionately short stature, referred to as spondyloepiphyseal dysplasia of Maroteaux, are described.
In patients who have this syndrome, the abnormalities are confined to the musculoskeletal system.
The ... | 4 |
287 | Giant cell tumor of bone. A clinicopathologic and DNA flow cytometric analysis.
Flow cytometric DNA analysis was performed on 60 cases of giant cell tumor of bone and the results were correlated with the clinicopathologic features.
Tumors studied were from 31 men and 29 women whose ages ranged from 18 to 62 years (me... | 3 |
2,449 | Pursuing mild elevations of liver enzyme values to exclude hemochromatosis.
To determine whether physicians in an academic medical center excluded hemochromatosis as a diagnosis in a population of patients with mildly elevated liver enzyme values, we reviewed 100 charts of patients with both aspartate aminotransferase... | 17 |
2,391 | Serial evaluation of lipid profiles and risk factors for development of hyperlipidemia after cardiac transplantation.
To determine the prevalence, time course and factors responsible for hyperlipidemia after heart transplantation, 83 consecutive 1-year survivors were studied.
By 1 year, 83% of patients had serum tota... | 17 |
1,541 | The establishment of an ovum donation program using a simple fixed-dose estrogen-progesterone replacement regimen.
Most ovum donation (OD) programs involve cycle synchronization between recipient and donor for normally cycling recipients and a complex estrogen-progesterone replacement regimen for recipients with ovari... | 12 |
3,351 | Role of membrane proteins in monosodium urate crystal-membrane interactions. II. Effect of pretreatments of erythrocyte membranes with membrane permeable and impermeable protein crosslinking agents.
Intact, human erythrocytes were pretreated with membrane permeable, dimethyl adipimidate (DMA) and dimethyl suberimidate... | 22 |
2,936 | Efficacy of tetracaine-adrenaline-cocaine topical anesthetic without tetracaine for facial laceration repair in children [published erratum appears in Pediatrics 1991 Feb;87(2):185]
To determine whether the tetracaine component traditionally used in tetracaine-adrenaline-cocaine (TAC) is necessary to obtain effective ... | 20 |
1,764 | Percutaneous popliteal approach for angioplasty of superficial femoral artery occlusions.
Angioplasty using the percutaneous popliteal approach was utilized in 50 patients (PTS) to recanalize 59 occluded superficial femoral arteries which had been unsuccessfully canalized by using the antegrade approach because of eit... | 13 |
1,188 | Innervation territories for touch and pain afferents of single fascicles of the human ulnar nerve. Mapping through intraneural microrecording and microstimulation.
The peripheral distribution of the fibre content of individual ulnar nerve fascicles supplying skin and muscles of the hand in human volunteers was indirec... | 9 |
824 | Carcinoma of the gallbladder.
Gallbladder cancer remains difficult to diagnose preoperatively.
However, recent work suggests that ultrasound may be effective.
Gallbladder cancer remains highly lethal despite aggressive therapy.
Extension of the disease beyond the mucosa predicts a poor chance of long-term survival.... | 5 |
2,878 | Controlled tissue expansion of a groin flap for upper extremity reconstruction.
A large upper extremity defect in an 8-year-old girl was resurfaced with an expanded groin flap.
Tissue expansion allowed complete coverage of the defect while minimizing the donor deformity.
Pretransfer expansion of pedicled flaps offer... | 20 |
2,296 | Interleukin-1 in human skin: dysregulation in psoriasis.
Cytokine dysregulation is an attractive concept to explain many of the observed abnormalities in psoriasis.
IL-1, in particular, can potentiate immune cellular activation, activate fibroblasts, and increase endothelial cell adhesiveness to leukocytes.
Here, we... | 16 |
2,224 | Ultrasonic forms of posterior staphyloma.
The most frequent deformations of the globe encountered in pediatric ophthalmology are staphylomas and colobomas.
In this paper we reviewed 16 ultrasonographically diagnosed staphylomas and classified the ultrasonographic patterns produced by staphyloma cases into four types:... | 15 |
430 | Anesthesia for craniotomy: a double-blind comparison of alfentanil, fentanyl, and sufentanil.
Using a prospective, randomized, and double-blind study design, alfentanil (n = 15), fentanyl (n = 14), or sufentanil (n = 16), in combination with N2O, were administered to patients undergoing craniotomy for supratentorial t... | 3 |
1,559 | Simplified method for estimating true aortic valve mean gradient from simultaneous left ventricular and peripheral arterial pressure recordings.
Estimation of the aortic valve gradient by simultaneous recording of left ventricular and peripheral arterial pressures is subject to error due to delay and modulation of the... | 13 |
1,230 | Efficacy of methylphenidate among mentally retarded children with attention deficit hyperactivity disorder.
Twelve children with IQ scores of 50 to 74 (educable mental retardation) who met rigorous diagnostic criteria for attention deficit hyperactivity disorder participated in a double-blind crossover study of the ef... | 9 |
992 | Surfactant replacement improves lung recoil in rabbit lungs after acid aspiration.
We tested the hypothesis that surfactant replacement would be beneficial in the acid-aspiration model of acute lung injury.
HCl (0.1 N, 2 ml/kg) was injected into the trachea of excised rabbit lungs (n = 8).
Control lungs (n = 4) had ... | 7 |
2,143 | HLA-B38, DR4, DQw3 and clozapine-induced agranulocytosis in Jewish patients with schizophrenia.
Agranulocytosis develops in approximately 1% of patients with chronic schizophrenia treated with the atypical neuroleptic drug clozapine.
Previous studies have not identified the mechanism or risk factors for this adverse ... | 14 |
2,298 | Lymphocyte adhesion to psoriatic dermal endothelium: mechanism and modulation.
Psoriasis is characterized by the hyperproliferation of keratinocytes in the epidermis and the accumulation of activated CD4+ T lymphocytes in the upper dermis.
We have recently tested the hypothesis that the abnormal endothelial prolifera... | 16 |
2,950 | Improved trauma care in a rural hospital after establishing a level II trauma center.
A study of motor vehicle accident deaths occurring in Napa County, California, from 1979 through 1983 showed that there was a preventable death rate of 42% for deaths that were not related to central nervous system injuries.
After d... | 20 |
981 | Inhibition of exercise-induced bronchoconstriction by MK-571, a potent leukotriene D4-receptor antagonist
BACKGROUND.
Exercise is a common stimulus of bronchoconstriction in subjects with asthma, who also have bronchoconstriction after inhaling the sulfidopeptide leukotriene D4 (LTD4).
The purpose of this study was... | 7 |
1,478 | The role of tubal pathology and other parameters in ectopic pregnancies occurring in in vitro fertilization and embryo transfer.
Contradictory findings were reported concerning the role of tubal disease in the genesis of ectopic pregnancy in in vitro fertilization and embryo transfer (IVF-ET).
We report on six ectopi... | 12 |
2,570 | Failure of T cell receptor-anti-CD3 monoclonal antibody interaction in T cells from marrow recipients to induce increases in intracellular ionized calcium.
There are multiple immune defects in T cells from recipients after bone marrow transplantation (BMT).
This study examines recipient T cells for increases in intra... | 19 |
1,153 | Relief of injection pain in adults. EMLA cream for 5 minutes before venepuncture.
The effectiveness of skin anaesthesia after 5 minutes' topical application of a lignocaine-prilocaine cream was evaluated.
One hundred and twenty patients estimated the pain of antecubital venepuncture both on a linear scale and verball... | 9 |
782 | Interventional gallbladder procedures.
Interventional radiologic procedures in the gallbladder are influencing both the diagnosis and therapy of many gallbladder disorders.
Current diagnostic and therapeutic percutaneous techniques offer important alternatives for their management.
This article highlights the spectr... | 5 |
1,539 | A morphological and immunological study of human placental bed biopsies in miscarriage.
Placental bed biopsies were examined in three groups of pregnant women for maternal vascular response to placentation as well as for the presence of cells associated with local immunosuppression activity.
In the group of women und... | 12 |
3,131 | Observer reliability in detecting surreptitious random occlusions of the monaural esophageal stethoscope.
The esophageal stethoscope is used often during anesthesia to monitor ventilation and cardiac function.
Deficiencies in observer vigilance may limit the effectiveness of this monitoring instrument.
The aim of th... | 22 |
432 | Colorectal cancer: evidence for distinct genetic categories based on proximal or distal tumor location
PURPOSE: To examine studies of normal colon and colorectal cancer for evidence that the location of the primary tumor proximal or distal to the splenic flexure of the colon may determine distinct genetic categories ... | 3 |
2,780 | Effects of alcohol on the import of aldehyde dehydrogenase precursor into rat liver mitochondria.
We previously showed that incubation of rat liver mitochondria with alcohols resulted in the inhibition of the import of aldehyde dehydrogenase precursor but not that of ornithine transcarbamylase precursor (Wang TTY, Far... | 20 |
542 | Expression of placental alkaline phosphatase in gastric and colorectal cancers. An immunohistochemical study using the prepared monoclonal antibody.
The authors developed monoclonal antibodies (MoAb) against human placental alkaline phosphatase (PLAP).
Four specific MoAb reacting only with PLAP and two nonspecific Mo... | 3 |
1,619 | Hemodynamics in internal carotid artery occlusion examined by positron emission tomography.
Using positron emission tomography in nine patients with minor strokes, unilateral internal carotid artery occlusion, and good collateral circulation through the anterior portion of the circle of Willis, we analyzed regional ce... | 13 |
1,324 | Basic evaluation of female urinary incontinence.
Urinary incontinence is a common disorder that is frequently underreported because of its social implications.
Although several types of urinary incontinence are recognized, they can be generally classified as failure of the bladder to store or failure of the urethral ... | 11 |
3,301 | Diclofenac for day-care arthroscopy surgery: comparison with a standard opioid therapy.
Sixty unpremedicated patients presenting for day-care arthroscopy surgery were allocated randomly to receive diclofenac 1 mg kg-1 i.m., fentanyl 1 microgram kg-1 i.v.
or no analgesic during the course of anaesthesia.
Patients rec... | 22 |
3,123 | Feasibility and cost savings of outpatient electrophysiologic testing.
The feasibility of outpatient electrophysiologic testing was examined by reviewing 100 consecutive outpatient tests performed in 95 patients.
Seventy-one of the patients (75%) had no underlying heart disease.
The electrophysiologic tests were per... | 22 |
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