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1,311 | Economics of screening for carcinoma of the prostate.
The proposition of whether to adopt a system of mass screening for carcinoma of the prostate in the U.S.
is well suited to the clinical decision analysis approach.
The authors demonstrate this by using available data, which suggest that offering a screening progr... | 11 |
1,237 | Synaptic transmission in human neocortex removed for treatment of intractable epilepsy in children.
Synaptic transmission to pyramidal cells was studied in slices of neocortex resected from infants and children (n = 10, age 8 months to 13 years) undergoing surgical treatment for intractable epilepsy.
Most specimens w... | 9 |
492 | Comparative study of cutaneous T-cell lymphoma and adult T-cell leukemia/lymphoma. Clinical, histopathologic, and immunohistochemical analyses.
An important disease entity distinct from cutaneous T-cell lymphoma (CTCL) in Japan is adult T-cell leukemia/lymphoma (ATL), which usually shows the same phenotype as CTCL, i.... | 3 |
1,600 | The daylong pattern of the antianginal effect of long-term three times daily administered isosorbide dinitrate
Three times daily administration of isosorbide dinitrate may avoid much of the tolerance seen with more frequent dosing.
To determine the daylong pattern of the antianginal effect of three times daily isoso... | 13 |
3,066 | Neurological phenomena during emergence from enflurane or isoflurane anaesthesia.
During emergence from anaesthesia, transient neurological signs that would usually be considered pathological may appear.
The objective of this randomized, patient (n = 30) and observer-blinded study was to compare prospectively the inc... | 22 |
1,422 | Non-heparin hemodialysis with oral administration of newly developed antiplatelet agent.
Non-heparin hemodialysis (HD) was successfully done in anuric dogs with the oral administration of a newly developed antiplatelet agent, 4-cyano-5,5-bis(4-methoxyphenyl)-4-pentenoic acid, (E5510, Eisai Pharmaceutical Co., Japan).
... | 11 |
150 | Geographical distribution of Plasmodium falciparum erythrocyte rosetting and frequency of rosetting antibodies in human sera.
Uninfected erythrocytes bind spontaneously to those infected with certain strains of Plasmodium falciparum.
This is known as spontaneous erythrocyte rosetting.
We have studied the occurrence ... | 2 |
3,077 | Late results with Carpentier-Edwards porcine bioprosthesis.
From 1977 to 1984, 429 patients underwent aortic valve replacement (AVR), and 339 underwent mitral valve replacement (MVR) with a Carpentier-Edwards bioprosthesis.
Early mortality for AVR was 4.6% (isolated AVR, 1.9%) and for MVR was 5.3% (isolated MVR, 4.1%... | 22 |
221 | Male breast cancer.
Male breast cancer is uncommon but important.
The diagnosis is easily made by breast biopsy, and patients are presenting earlier in the course of the disease than in the past.
Despite this, patients are often first seen with tumors that have metastasized to the axillary nodes, which markedly decr... | 3 |
424 | Increase of beta 1-6-branched oligosaccharides in human esophageal carcinomas invasive against surrounding tissue in vivo and in vitro.
The -GlcNAc beta 1-6Man- (beta 1-6) branched N-glycosidic oligosaccharides expressed on tumor cells have been found to contribute to malignant and metastatic potential in experimental... | 3 |
2,823 | Alcohol and trauma.
Countermeasures to alcohol-related trauma are essential.
The public perception that there is low risk of detection and punishment for alcohol-precipitated violence is being addressed.
Current legislation is aimed at decreasing the availability of alcohol (e.g., adjusting legal drinking age, decre... | 20 |
1,248 | Phenotypic and functional characterization of T cells from patients with myasthenia gravis.
A study of cell surface phenotypes of PBL of myasthenia gravis (MG) patients showed that their T cells had a significantly higher percentage of 4B4+ T cells (the helper/inducer subset) than age- and sex-matched controls.
The P... | 9 |
2,089 | Complement activation and use of a cell saver in cardiopulmonary bypass.
Complement activation was evaluated in ten patients undergoing cardiopulmonary bypass (CPB) and intraoperative blood salvage with a cell saver (CS) to assess the inflammatory response related to the CS.
The washed red blood cell concentrate was ... | 13 |
1,394 | Extracorporeal removal of anti-HLA antibodies in transplant candidates.
We report on the results of a clinical trial in which 14 transplant candidates were treated with an extracorporeal immunoadsorption system using Protein A that selectively removes immunoglobulin from plasma; we also assessed the dynamics of anti-H... | 11 |
2,179 | Rheologic properties of mixed hemoglobin gels: deoxyhemoglobins S and F.
To obtain new information concerning the behaviors--and in turn, the structures--of gels formed from mixtures of S and F hemoglobins, their rheologic properties have been characterized by stress relaxation.
The variables manipulated were (1) ini... | 14 |
1,659 | Myocardial perfusion imaging with technetium-99m sestamibi SPECT in the evaluation of coronary artery disease.
Technetium-99m (Tc-99m) sestamibi is a new myocardial perfusion imaging agent that offers significant advantages over thallium-201 (Tl-201) for myocardial perfusion imaging.
The results of the current clinic... | 13 |
2,412 | Reduced insulinotropic effects of glucagonlike peptide I-(7-36)-amide and gastric inhibitory polypeptide in isolated perfused diabetic rat pancreas.
The pathophysiological role of incretin in diabetes mellitus has not been established.
We therefore examined the effects of glucagonlike peptide I-(7-36)-amide (truncate... | 17 |
573 | Internists' practices in health promotion and disease prevention. A survey.
OBJECTIVE: To estimate internists' use of disease prevention and health promotion activities, and to explore demographic, professional, behavioral, psychological, cognitive, and organizational factors associated with the use of such practices.... | 3 |
2,791 | Long-term therapeutic use of benzodiazepines. II. Effects of gradual taper.
We compared the effect on withdrawal severity and acute outcome of a 25% per week taper of short half-life vs long half-life benzodiazepines in 63 benzodiazepine-dependent patients.
Patients unable to tolerate taper were permitted to slow the... | 20 |
942 | Chronic obstructive pulmonary disease.
Chronic obstructive pulmonary disease is indeed a multifaceted illness.
The obstructive picture is the result of multiple pathologic processes.
The most common cause is cigarette smoking.
The key to decreasing the incidence of this disease is education to prevent people from s... | 7 |
2,662 | Clearance of 99mTc-DTPA in pigeon fancier's hypersensitivity pneumonitis.
The rate of clearance of inhaled 99mTc-DTPA was measured in 20 nonsmoking pigeon fanciers and 7 control subjects.
The degree of their avian contact and pigeon-related symptoms were noted, humoral immune response in the form of IgG antibody to p... | 19 |
1,382 | Bidirectional incompatibility between conspecific populations of Drosophila simulans
Cytoplasmic incompatibility (CI) describes the phenomenon whereby eggs fertilized by sperm from insects infected with a rickettsial endosymbiont fail to hatch.
Unidirectional CI between conspecific populations of insects is a well d... | 11 |
2,465 | Slow glucose removal rate and hyperinsulinemia precede the development of type II diabetes in the offspring of diabetic parents.
OBJECTIVE: To determine whether insulin resistance or insulin deficiency is primary in the pathogenesis of type II diabetes.
DESIGN: Cohort analytic study of persons with normal glucose tol... | 17 |
2,860 | Anomie, alcohol abuse and alcohol consumption: a prospective-analysis.
Cross-sectional and 36-month prospective analyses of the relationships among anomie and both alcohol abuse and alcohol consumption patterns provided little support that anomie was directly associated with ethanol ingestion patterns in a sample of 3... | 20 |
3,250 | Treatment of chronic facial palsy by transplantation of the neurovascularized free rectus abdominis muscle.
We performed neurovascularized free rectus abdominis muscle transplantations in two patients with chronic facial palsy.
In one patient, the postoperative course was uneventful, but the patient died from rupture... | 22 |
3,107 | Distribution of pulmonary capillary transit times in recruited networks.
When pulmonary blood flow is elevated, hypoxemia can occur in the fastest-moving erythrocytes if their transit times through the capillaries fall below the minimum time for complete oxygenation.
This desaturation is more likely to occur if the d... | 22 |
1,630 | Contribution of transesophageal echocardiography to patient diagnosis and treatment: a prospective analysis.
The capability of transesophageal (TEE) versus transthoracic (TTE) echocardiography as a diagnostic tool in clinical practice was prospectively examined in 86 consecutive cases.
A conclusive diagnosis was poss... | 13 |
3,125 | The Senior Care Study. The optimal use of medications in acutely ill older patients.
Geriatric assessment units have improved pharmacotherapy for their patients by decreasing the number of medications prescribed.
The Senior Care Study, a randomized controlled trial, compared a multidisciplinary-team approach to patie... | 22 |
730 | Exacerbation of chronic active hepatitis type B after short-term corticosteroid therapy resulting in fatal liver failure.
The case of a 36-yr-old male with chronic active type B hepatitis in whom 4-wk prednisone therapy resulted in prolonged and fatal exacerbation of liver disease is described.
Thus, short-term corti... | 5 |
2,102 | Comparison of right ventricular and biventricular circulatory support in a porcine model of right heart failure.
The effects of right ventricular (RVAD) and biventricular assist devices (BVAD) in an acute porcine model of right heart ischemic failure produced by occluding the right coronary artery for 2 min (RCAO) wer... | 13 |
668 | Incidence of cervical spinal stenosis in professional and rookie football players.
Sagittal canal/vertebral body ratios were measured on cervical spine lateral radiographs of 124 professional football players and 100 rookie football players.
A total of 894 levels were measured in 224 players.
Thirty-two percent (40)... | 4 |
2,428 | Effect of central obesity on regulation of carbohydrate metabolism in obese patients with varying degrees of glucose tolerance.
It has been proposed that central obesity, by virtue of the enhanced lipolytic activity of abdominal adipose tissue, leads to higher plasma FFA concentrations, which, in turn, decrease both h... | 17 |
2,562 | Formoterol in the treatment of nocturnal asthma.
Formoterol fumarate is a new beta 2-adrenergic agonist with a long lasting effect.
The bronchospasmolytic effect of 12 micrograms of formoterol was compared with that of 200 micrograms of albuterol (salbutamol) in a single-center, double-blind, randomized within-patien... | 19 |
1,459 | Contraception and ectopic pregnancy risk.
Studies of the association of ectopic pregnancy with contraception have generated a conflicting array of results because of methodologic differences between studies.
We estimated the absolute incidence rates of ectopic pregnancy for various contraceptives by multiplying the p... | 12 |
3,265 | Relation between transcardiac and transthoracic current during defibrillation in humans.
Conceptually, transthoracic defibrillation threshold current can be considered a function of at least two quantities.
It is directly proportional to the transcardiac threshold current and inversely proportional to the transcardia... | 22 |
1,286 | A miniaturized vitrectomy system for vitreous and retinal biopsy.
The author has developed a miniaturized vitrectomy system and its accessories with the size of a 23-gauge needle.
The hand-piece can be inserted inside the eye through a Ziegler knife track.
This instrument can be used for "atraumatic" removal of vitr... | 10 |
179 | Lewis system alterations in gastric carcinogenesis.
Alterations in the expression of type 1 blood group-related antigens (Lewis a and b) were examined immunohistochemically in 371 consecutives gastric biopsy and 80 surgical specimens from patients of gastric carcinoma.
The ABH and Lewis phenotype and secretor status ... | 3 |
1,229 | The influence of warning signal timing and cognitive preparation on the aversiveness of electric shock.
Many medical and dental procedures are noxious.
Finding an optimal way of warning patients concerning the aversive procedures could help them to cope better.
A model for the effective use of a warning signal in co... | 9 |
2,737 | Critical care for clonidine poisoning in toddlers.
Clonidine may be a source of serious toxicity when ingested by toddlers.
We describe 11 cases of clonidine ingestion by toddlers (mean dose 0.15 mg/kg; range 0.01 to 0.57).
The source of the clonidine was a grand-parent in six of 11 cases.
Symptoms included altered... | 20 |
3,168 | Estrogen receptor level determines sex-specific in vitro transcription from the Xenopus vitellogenin promoter.
Female-specific expression of the Xenopus laevis vitellogenin gene was reconstituted in vitro by addition of recombinant vaccinia-virus-produced estrogen receptor to nuclear extracts from male livers, in whic... | 22 |
3,122 | Balloon expandable stent implantation in stenotic right heart valved conduits.
Although valved conduits have been used successfully in severe forms of right ventricular-pulmonary artery discontinuity, progressive valved conduit stenosis is an important clinical problem.
To determine the feasibility of reducing right ... | 22 |
3,295 | Simultaneous 'dual system' rehabilitation in the treatment of facial paralysis.
Simultaneous dual system rehabilitation of facial paralysis involves using two independent reanimation techniques to optimize facial movement in both a quantitative and qualitative manner.
These techniques involve the use of nerve graftin... | 22 |
1,051 | Auditory hallucinations and smaller superior temporal gyral volume in schizophrenia.
Recent neuropathologic investigations in schizophrenia report smaller volume of medial temporal lobe structures.
These findings are confirmed by preliminary magnetic resonance imaging (MRI) studies.
Direct stimulation of lateral tem... | 9 |
1,576 | Caliber-persistent artery of the stomach (Dieulafoy's vascular malformation).
Caliber-persistent artery of the stomach (also known as cirsoid aneurysm, Dieulafoy's lesion, and submucosal arterial malformation) is clinically manifested as recurrent, massive, often fatal hematemesis.
The lesion often is not seen endosc... | 13 |
493 | von Willebrand factor in head and neck cancer.
Laboratory abnormalities in blood coagulation factors are common in patients with cancer but the significance is unknown.
Twenty-eight patients with head and neck cancer were studied at the time of diagnosis.
Twenty-five were advanced-stage (III or IV) patients.
Levels... | 3 |
1,014 | Dysequilibrium and otitis media with effusion: what is the association?
An association between non-suppurative otitis media (NSOM) and symptoms of dysequilibrium has been observed but not previously quantified in children (Gates, 1980; Busis, 1983; Blayney and Coleman, 1984).
This study compared the incidence of bala... | 8 |
1,517 | A new method for the dressing of free skin grafts.
Using adhesive drapes and a disposable suction drain, a new method for the dressing of free skin grafts has been devised.
The graft is compressed by pressure that is equivalent to the negative pressure of the suction drain.
This method can apply uniform and constant... | 12 |
3,145 | Acute hypervolaemic haemodilution to avoid blood transfusion during major surgery
16 patients underwent acute hypervolaemic haemodilution with dextran 40 and Ringers lactate, to see whether this procedure could avoid preoperative blood transfusion.
Packed cell volume (PCV) and oxygen extraction decreased, and cardia... | 22 |
382 | Inhibition of tumor growth in a glioma model treated with boron neutron capture therapy.
This investigation attempts to determine whether increased survival time seen when the F98 glioma model is treated with boron neutron capture therapy (BNCT) is a result of inhibition of tumor growth caused by radiation-induced alt... | 3 |
2,116 | Apical segmental dysfunction in hypertrophic cardiomyopathy: subgroup with unique clinical features.
A segmental wall motion abnormality is an unusual finding in patients with hypertrophic cardiomyopathy.
To clarify its clinical significance, 48 patients with hypertrophic cardiomyopathy were analyzed.
Eight patients... | 13 |
2,429 | Beta-cell cytoadherent lymphocytes in some subjects at risk for type 1 (insulin-dependent) diabetes: progression to diabetes within 2 years.
The increased binding in vitro of CD3 CD4 T-lymphocytes from type 1 (insulin-dependent) diabetic patients to beta-cell membrane antigens compared to lymphocytes from control subj... | 17 |
1,590 | Multiple breakpoint method for measuring effect of antibiotics on endocarditis strains of streptococci.
The activity of penicillin alone and combined with aminoglycoside on endocarditis strains of streptococci was examined.
Good assay reproducibility was obtained by the use of logarithmic phase cultures standardised ... | 13 |
1,695 | Does isoflurane lead to a higher incidence of myocardial infarction and perioperative death than enflurane in coronary artery surgery? A clinical study of 1178 patients
To examine if the choice of volatile agents influences cardiac outcome in coronary artery surgery, 1178 patients undergoing elective coronary artery ... | 13 |
2,406 | Insulin use in NIDDM. Rationale based on pathophysiology of disease.
Because basal hyperglycemia is a major feature in non-insulin-dependent diabetes mellitus, diabetes control can be monitored by the fasting blood glucose concentration.
A hierarchical sequence of therapies is proposed in which the major aim is to ma... | 17 |
2,580 | Bacterial lipopolysaccharide transforms mesangial into proliferative lupus nephritis without interfering with processing of pathogenic immune complexes in NZB/W mice.
Systemic lupus erythematosus is a multifactorial systemic disease in which genetic, immunologic, hormonal, and environmental factors may contribute to d... | 19 |
2,239 | Prevalence of additional cardiovascular anomalies in patients referred for transcatheter closure of patent ductus arteriosus.
Catheter closure of the patent ductus arteriosus is now a reality.
The purpose of this study was to establish the prevalence of associated cardiovascular defects and the accuracy of echocardio... | 15 |
342 | Intraperitoneal yttrium-90-labeled monoclonal antibody in ovarian cancer
From March 1987 to March 1988, a phase I to II study was carried out in 25 patients with ovarian cancer.
They received escalating doses of intraperitoneally (IP) administered yttrium-90 (Y-90)-labeled monoclonal antibody, HMFG1, against a tumor... | 3 |
127 | Impact of cytomegalovirus infection on organ transplant recipients.
Cytomegalovirus (CMV) is the single most important infectious agent affecting recipients of organ transplants, with at least two-thirds of these patients having CMV infection 1-4 months after transplantation.
Latently infected allografts are the majo... | 1 |
1,807 | The effects of phenylephrine on right ventricular performance in patients with pulmonary hypertension
Pulmonary hypertension causes right ventricular ischemia and failure as a result of increased afterload combined with reduced coronary blood flow.
Increasing coronary driving pressure by raising aortic pressure with... | 13 |
2,484 | Hydroquinone-induced localized exogenous ochronosis treated with dermabrasion and CO2 laser.
Exogenous localized ochronosis can result from the repeated use of hydroquinone-containing creams, many of which are available over the counter.
We report a case that was managed by dermabrasion and CO2 laser.
The incidence ... | 17 |
2,351 | WHO Multinational Project for Childhood Diabetes. WHO Diamond Project Group.
Insulin-dependent diabetes mellitus (IDDM) is one of the most important chronic diseases of children worldwide.
IDDM leads to an 8- to 10-fold excess risk of mortality in developed countries, whereas in developing countries, most cases die w... | 17 |
1,120 | Fibrillation potential amplitude and muscle atrophy following peripheral nerve injury.
Maximum peak-to-peak fibrillation potential amplitude was measured in 69 subjects between 7 days and 10 1/2 years post complete or partial peripheral nerve injury.
Mean amplitude during the first 2 months was 612 muV; third and fou... | 9 |
2,414 | Insulinlike activity of new antidiabetic agent CP 68722 in 3T3-L1 adipocytes.
We examined the in vitro effects of CP 68722, a novel antidiabetic agent, in 3T3-L1 adipocytes.
CP 68722 stimulated 2-deoxyglucose uptake in the absence of insulin.
At least 30 min of incubation were required for stimulation of uptake.
Th... | 17 |
546 | Extrahepatic metabolism of morphine occurs in humans.
The pharmacokinetics of morphine was studied in six patients in whom a radiologic localization of an insulinoma was to be performed under general anesthesia.
Sampling was done in the peripheral artery, the mesenteric vein in five of the six patients, the hepatic v... | 3 |
1,785 | Early and late results after isolated coronary artery bypass surgery in 159 patients aged 80 years and older.
We have studied 159 patients 80 years of age or older who have had isolated coronary artery bypass grafting (CABG) since 1977.
Eighty-seven percent have had surgery since 1984.
Two thirds of the patients wer... | 13 |
2,782 | Examination of Cloninger's type I and type II alcoholism with a sample of men alcoholics in treatment.
Cloninger's clinical method of classifying alcoholics into two groups (Types I and II) was examined with data obtained from 360 VA hospitalized male alcoholic patients.
For operational criteria, the Cloninger clinic... | 20 |
2,799 | Prospective evaluation of gastric emptying in the self-poisoned patient.
The authors prospectively studied the effect of gastric emptying (GE) and activated charcoal (AC) upon clinical outcome in acutely self-poisoned patients.
Presumed overdose patients (n = 808) were treated using an alternate day protocol based on... | 20 |
3,006 | An effective and adaptable transvenous defibrillation system using the coronary sinus in humans.
With use of a coronary sinus catheter electrode, a right ventricular catheter electrode and a chest wall patch electrode system, defibrillation threshold voltage, current and energy were measured with four distinct transve... | 22 |
2,911 | Treatment of digitalis intoxication with emphasis on the clinical use of digoxin immune Fab.
Many studies and cases of digitalis intoxication have been reported since the time of William Withering's first publication in 1785.
Recognition and management of digitalis toxicity is challenging.
Before digoxin immune Fab ... | 20 |
936 | Serologic evidence of subclinical pertussis in immunized children.
Incidental to a vaccine study involving 783 immunized children conducted at two study sites, inner city children had significantly higher geometric mean pertussis agglutinin titers compared with suburban children just before the fourth dose of diphther... | 7 |
491 | The effect of dietary omega-3 fatty acids (fish oil) on azoxymethanol-induced focal areas of dysplasia and colon tumor incidence.
MaxEPA (MA), a fish oil high in omega-3 fatty acids, was combined with various levels of corn oil (CO), rich in omega-6 fatty acids, and fed to female CF1 mice.
The three fish oil blends w... | 3 |
2,479 | Role of two types of glucose transporters in enlarged adipocytes from aged obese rats.
The mechanism of insulin-resistant glucose-transport activity in enlarged aged adipocytes was examined.
Glucose-transport activity was assessed by measuring 3-O-methylglucose transport and the concentration of HepG2 erythrocyte/glu... | 17 |
2,301 | The expression of retrovirus-like particles in psoriasis.
Retrovirus-like particles have been isolated from patients with psoriasis.
Antigens crossreacting with the major internal protein, pso p27, of these particles have been demonstrated in the wall of dermal vessels and in a subfraction of cells in psoriatic lesio... | 16 |
2,382 | Hyponatremia in rats induces downregulation of vasopressin synthesis.
Hyponatremia due to inappropriate secretion of vasopressin is a common disorder in human pathophysiology, but vasopressin synthesis during hypoosmolality has not been investigated.
We used a new method to quantitate synthesis of vasopressin in rats... | 17 |
1,060 | Vasoactive peptide release in the extracerebral circulation of humans during migraine headache.
The innervation of the cranial vessels by the trigeminal nerve, the trigeminovascular system, has recently been the subject of study in view of its possible role in the mediation of some aspects of migraine.
Since stimulat... | 9 |
1,679 | Efficacy of acebutolol after acute myocardial infarction (the APSI trial). The APSI Investigators.
A randomized, placebo-controlled trial was carried out to determine the effectiveness of acebutolol in preventing late death in high-risk patients surviving an acute myocardial infarction (MI).
The average 1-year mortal... | 13 |
105 | Risk factors for Staphylococcus aureus nosocomial pneumonia in critically ill patients.
Staphylococcus aureus nosocomial pneumonia has become an important infection not only because of an apparently increasing incidence but also because of its high mortality rate.
A total of 50 episodes of nosocomial pneumonia in cri... | 0 |
3,330 | Improved biocompatibility by postfixation treatment of aldehyde fixed bovine pericardium.
Long-standing release of locally cytotoxic aldehyde concentrations is responsible for lack of spontaneous endothelialization and increased calcification of glutaraldehyde fixed bovine pericardium.
Postfixation treatment with ami... | 22 |
211 | Results of conservative surgery and radiation therapy for breast cancer.
For stage I or II breast cancer, conservative surgery and radiation therapy are as effective as modified radical or radical mastectomy.
In most cases, cosmetic considerations and the availability of therapy are the primary concerns.
The extent ... | 3 |
1,341 | Comparison of pathological lesions on repeated renal biopsies in 73 patients with primary IgA glomerulonephritis: value of quantitative scoring and approach to final prognosis.
In order to improve our possibility of establishing a long-term prognosis in IgA nephritis, 73 patients out of a cohort of 282, followed over ... | 11 |
1,548 | Prevalence of aortic regurgitation by color flow Doppler in relation to aortic root size.
To determine whether there is a correlation between aortic root size and the prevalence of aortic regurgitation, we performed color flow Doppler echocardiographic studies on 1015 consecutive patients during a 3-month period.
Pat... | 13 |
1,846 | Transesophageal echocardiography to detect atrial clots in candidates for percutaneous transseptal mitral balloon valvuloplasty.
Left atrial thrombi are common in patients with mitral stenosis.
When percutaneous balloon mitral valvuloplasty is performed on such patients, there is a potential risk of thrombus dislodgm... | 13 |
1,256 | Topical timolol and serum lipoproteins.
Oral timolol taken for the treatment of systemic hypertension has been shown to affect adversely serum lipoprotein levels.
In a 15-week study on 19 patients topical timolol therapy for raised intraocular pressure was found to have no significant adverse effect on serum lipoprot... | 10 |
2,366 | Association of elevated fasting C-peptide level and increased intra-abdominal fat distribution with development of NIDDM in Japanese-American men.
The Japanese-American population of King County, Washington, is known to have a high prevalence of non-insulin-dependent diabetes mellitus (NIDDM).
As part of a community-... | 17 |
2,579 | Morphometric analysis of follicular center cell lymphomas.
The Lukes/Collins classification of non-Hodgkin's lymphomas subdivides follicular center cell (FCC) lymphomas into four categories based on nuclear size, shape, and state of transformation.
Because of the well-recognized difficulty in making these subdivision... | 19 |
3,162 | Low dose amitriptyline in chronic pain: the gain is modest.
In the double-blind placebo-controlled study presented here, the effects were investigated of a low dose of amitriptyline (75 mg) in patients with chronic pain of various origins.
The active drug was superior to placebo in reducing pain intensity.
The reduc... | 22 |
3,053 | Comparison of four pulse oximeters: effects of venous occlusion and cold-induced peripheral vasoconstriction.
The ability of four pulse oximeters (the Ohmeda 3700, Nellcor N100 and N200 and the Datex Oscar) to detect hypoxaemia was determined in the presence of venous obstruction and cold-induced peripheral vasoconstr... | 22 |
871 | Histopathologic grading of salivary gland neoplasms: III. Adenoid cystic carcinomas.
Histopathologic grading of adenoid cystic carcinomas can provide valuable prognostic information, particularly when the presence or absence of a solid growth architecture is noted.
Other growth patterns, exemplified by a tubuloductal... | 6 |
2,853 | The effects of fluoxetine in the overdose patient.
Fluoxetine (Prozac) is a new antidepressant, first marketed in the United States in January 1988.
Only limited toxicologic information during a fluoxetine overdose is available.
The goal of this prospective multi-center study was to develop a toxicity profile of ini... | 20 |
162 | Computed tomography of metastatic cervical lymph nodes. A clinical, computed tomographic, pathologic correlative study.
A retrospective comparative study of 63 neck dissections was undertaken to evaluate further the accuracy of high-resolution computed tomography (CT) in the detection of nodal metastases, as previous ... | 3 |
2,379 | Diabetes and the myo-inositol paradox.
To test the general applicability of the hypothesis that diabetes mellitus causes increased polyol pathway activity, decreased tissue free myo-inositol, and resultant pathological changes in tissues susceptible to the ravages of diabetes, we measured glucose, sorbitol, and myo-in... | 17 |
52 | Positive Lyme serology in subacute bacterial endocarditis. A study of four patients.
Lyme borreliosis is a multisystem inflammatory disorder caused by the tick-borne spirochete Borrelia burgdorferi.
Clinical manifestations are protean, involving the skin, joints, peripheral and central nervous systems, and the heart.... | 0 |
3,303 | Late postoperative episodic and constant hypoxaemia and associated ECG abnormalities.
Twenty-two patients without cardiopulmonary disease and undergoing elective major abdominal surgery were monitored continuously with a Holter tape recorder and a pulse oximeter on one night before operation and the first two nights a... | 22 |
2,734 | Isolated avulsion of the biceps femoris insertion. A case report.
The clinical, roentgenographic, and operative findings of an isolated biceps femoris avulsion in a 21-year-old man demonstrated the significance of the static stabilizers about the knee, menisci, and articular cartilage.
Examination of the dynamic stru... | 20 |
3,328 | Monitoring platelet interactions with prosthetic graft implants in a canine model.
This study shows that prosthetic arterial grafts stimulate platelets for as long as 1 year after implantation in a canine model.
Carotid-to-distal aorta Dacron (DuPont, Wilmington, DE) grafts (0.8 x 50.0 cm) were tunneled subcutaneousl... | 22 |
145 | Transmission indices of Loa loa in the Chaillu Mountains, Congo.
A longitudinal entomological survey of the vectors of loiasis was conducted in the Missama area (Lekoumou region) in the Congo from September 1987 to August 1989.
The principal catching site was a palm grove surrounded by forest 3 km from the village.
... | 2 |
2,850 | Cranial electrostimulation (CES) use in the detoxification of opiate-dependent patients.
This paper reviews the scientific literature on cranial electrostimulation (CES) as a non-chemical means to alleviate opiate withdrawal symptoms.
CES involves applying small amounts of electrical stimulation through electrodes ap... | 20 |
1,620 | Pharmacologic irreversible narrowing in chronic cerebrovasospasm in rabbits is associated with functional damage.
We studied isolated basilar artery segments from a rabbit model of chronic cerebrovasospasm.
Autologous blood placed around the basilar artery of rabbits killed 1, 2, 3, 4, 5, 6, 7, or 9 days later caused... | 13 |
2,006 | Evidence of hibernating myocardium by a new transesophageal echocardiographic technique.
Reversal of resting wall motion abnormalities after successful coronary angioplasty were documented in a patient with the use of a novel approach to stress testing.
Transesophageal stress echocardiography utilizes transesophageal... | 13 |
1,254 | A survey of the initial referral of children to an ophthalmology department.
We report on a survey of the referral of 525 children making their first visit to an ophthalmology department.
Information was gathered by interviewing the parents and reviewing the case notes.
Parents and relatives initiated the referrals ... | 10 |
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