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2,504 | Mechanism of increased gluconeogenesis in noninsulin-dependent diabetes mellitus. Role of alterations in systemic, hepatic, and muscle lactate and alanine metabolism.
To assess the mechanisms responsible for increased gluconeogenesis in noninsulin-dependent diabetes mellitus (NIDDM), we infused [3-14C]lactate, [3-13C]... | 17 |
704 | Duodenal ulcer and refined carbohydrate intake: a case-control study assessing dietary fibre and refined sugar intake
An association between duodenal ulceration and a low fibre intake and a high refined carbohydrate diet has been reported.
We therefore compared the current diet, smoking habits, social class, and pos... | 5 |
1,371 | Prospective comparison of plain abdominal radiography with conventional and digital renal tomography in assessing renal extracorporeal shock wave lithotripsy patients.
Most publications citing the effectiveness of renal extracorporeal shock wave lithotripsy have used plain abdominal radiography to assess residual calc... | 11 |
2,165 | Prenatal diagnosis of laryngeal atresia.
In a patient in whom preeclampsia developed at 23 weeks' gestation, ultrasonographic examination of the fetus showed enlarged edematous lungs, a compressed fetal heart, severe ascites, fetal hydrops, and placental edema.
Autopsy of the hydropic stillborn infant showed laryngea... | 14 |
798 | Extracellular matrix gene expression increases preferentially in rat lipocytes and sinusoidal endothelial cells during hepatic fibrosis in vivo.
Whether parenchymal or nonparenchymal liver cells play a predominant role in the pathophysiology of hepatic fibrosis has not been firmly established in vivo.
We have address... | 5 |
2,998 | High dietary fiber and low saturated fat intake among oligomenorrheic undergraduates.
Numerous functional risk factors are associated with the occurrence of secondary amenorrhea in young women.
Less is known regarding factors associated with the more prevalent problem of oligomenorrhea.
We have evaluated nutrient in... | 22 |
2,888 | Rapid visual colorimetry of peritoneal lavage fluid.
STUDY HYPOTHESIS: That visual colorimetry can be used to rapidly and precisely estimate the erythrocyte count of 1:5 dilutions of simulated peritoneal lavage fluid.
POPULATION: Fifty-four normal adult human subjects.
METHODS: The automated or chamber RBC count is ... | 20 |
1,526 | Establishment of pregnancies in humans after transcervical transfer of gametes immediately after oocyte retrieval.
This study, like that of Veersema et al.
demonstrates the feasibility of direct intrauterine transfer of gametes in initiating pregnancy.
Whether the success of this procedure can be further improved wi... | 12 |
2,924 | A survey of wound monitoring and topical antimicrobial therapy practices in the treatment of burn injury.
A survey was done to determine how burn wound microbial monitoring is performed and how topical antimicrobial agents are employed.
The survey was sent to 90 burn-care facilities, which comprised most of the major... | 20 |
294 | Final report of the French multicenter phase II study of the nitrosourea fotemustine in 153 evaluable patients with disseminated malignant melanoma including patients with cerebral metastases.
One hundred sixty-nine patients with histologic evidence of disseminated malignant melanoma, including patients with cerebral ... | 3 |
953 | Determination of serum concentrations of type III procollagen peptide in mechanically ventilated patients. Pronounced augmented concentrations in the adult respiratory distress syndrome.
Type III procollagen peptide (PCP) is a byproduct of type III collagen synthesis and a potential marker of collagen secretion.
In c... | 7 |
56 | The use of prophylactic furazolidone to control a nosocomial epidemic of multiply resistant Salmonella typhimurium in pediatric wards.
The nosocomial spread of enteric pathogens is often difficult to control in overcrowded pediatric wards.
During 1983 and 1984, despite cohorting of patients and enforced hand washing,... | 0 |
99 | Interleukin-1 receptor antagonist reduces mortality from endotoxin shock.
About five out of 1,000 patients admitted to hospital develop bacterial sepsis leading to shock, the mortality rate for which is high despite antibiotic therapy.
The infection results in hypotension and poor tissue perfusion, and eventually lea... | 0 |
3,256 | Effects of pill-giving on maintenance of placebo response in patients with chronic mild depression
Fifty outpatients with mild, chronic, mood-reactive depression whose mood improved markedly after a 10-day single-blind placebo trial were randomly assigned in a double-blind design either to have their placebo medicati... | 22 |
729 | Sucralfate used as adjunctive therapy in patients with severe erosive peptic esophagitis resulting from gastroesophageal reflux.
A total of 36 patients with grade 2 or greater erosive esophagitis and an abnormal 24-h pH monitor study, were treated in a randomized, double-blind fashion to assess the efficacy of sucralf... | 5 |
241 | Estimation of PR and ER by immunocytochemistry in breast cancer. Comparison with radioligand binding methods.
Immunocytochemical assays for progesterone receptor (PR) using monoclonal antirabbit PR antibodies (PR-ICA) and for estrogen receptor (ER) (ER-ICA) were compared with radioligand binding (dextran-coated charco... | 3 |
195 | Prognostic factors of hepatocellular carcinoma in the west: a multivariate analysis in 206 patients.
To investigate the prognostic factors in Western patients with hepatocellular carcinoma, 206 patients with confirmed diagnoses of hepatocellular carcinoma were studied in terms of survival.
All patients were diagnosed... | 3 |
3,130 | Placement of esophageal stethoscope by acoustic criteria does not consistently yield an optimal location for the monitoring of core temperature.
The esophageal stethoscope has evolved into a device for both acoustic and core temperature monitoring.
To test whether routine placement according to acoustic criteria resu... | 22 |
2,304 | Cyclosporine A in the treatment of psoriasis: a clinical and mechanistic perspective.
Cyclosporine A, a unique immunomodulatory agent, has been used increasingly over the last 5 years in the management of severe psoriasis.
The remarkable efficacy of this drug coupled with its known immunosuppressive properties have e... | 16 |
504 | Growth factor-dependent differentiation along the myeloid and lymphoid lineages in an immature acute T lymphocytic leukemia.
Bone marrow cells from a child with an immature (CD2+, CD5+, CD7+) acute T lymphocytic leukemia (T-ALL) were cultured in the presence and absence of human rIL-2, IL-3, or granulocyte-macrophage ... | 3 |
14 | Cerebrospinal fluid changes after 48 hours of effective therapy for Hemophilus influenzae type B meningitis.
Interval cerebrospinal fluid (CSF) analysis is often performed to assess efficacy of treatment for bacterial meningitis.
The authors reviewed 101 cases of pediatric bacterial meningitis resulting from Hemophil... | 0 |
2,160 | Impaired thermoregulation and thyroid function in iron-deficiency anemia.
Ten women with iron-deficiency anemia, 8 with depleted iron stores (nonanemic), and 12 control women, all of similar body fatness, were exposed to a 28 degrees C water bath to test the hypothesis that iron-deficiency anemia impairs thermoregulat... | 14 |
2,295 | Lymphocyte chemoattractants in psoriasis and normal skin.
The local production of lymphocyte attractants may influence both physiologic lymphocyte trafficking in the skin as well as the infiltration of these cells in pathologic states.
Recent evidence for the production of acidic lipid lymphocyte chemoattractants, pa... | 16 |
346 | Node-negative breast cancer: prognostic subgroups defined by tumor size and flow cytometry
Adjuvant systemic therapy for women with node-negative breast cancer is most easily justified for those patients at highest risk of relapse.
We have examined the impact of tumor size, histologic grade, estrogen receptor (ER) s... | 3 |
2,692 | Recognition of a B cell lymphoma by anti-idiotypic T cells.
Idiotypic IgM derived from a B cell lymphoma can act as a tumor-associated Ag, in that immunization with this purified protein generates an anti-idiotypic immune response that specifically suppresses tumor development.
Spleens of immune mice contain T cells ... | 19 |
328 | Insulin-like growth factor-I supports proliferation of autocrine thymic lymphoma cells with a pre-T cell phenotype.
We have studied the phenotypic characteristics and growth properties of murine T lymphoma cell lines derived from primary x-ray-induced thymic lymphomas at the earliest stage at which they can be detecte... | 3 |
2,018 | Collagen phenotypes during development and regression of myocardial hypertrophy in spontaneously hypertensive rats.
The myocardium contains collagen matrix that is a major determinant of its architecture, structural integrity, and mechanical properties.
This fibrillar matrix consists primarily of type I and type III ... | 13 |
2,841 | Diagnostic peritoneal lavage: accuracy in predicting necessary laparotomy following blunt and penetrating trauma.
The purpose of this study was to evaluate the ability of diagnostic peritoneal lavage (DPL) to predict intra-abdominal injuries that required surgical repair.
To do this, we retrospectively reviewed 944 p... | 20 |
880 | Confluence of pulmonary veins simulating a pulmonary mass.
Confluence of the pulmonary veins commonly appears on the frontal view of the chest and generally is easily recognized as such.
On plain film tomography, computerized tomography, and pulmonary angiography, the anatomy of convergence of pulmonary veins prior t... | 7 |
320 | Tissue preparation for simultaneous flow cytometric quantitation of tumour associated antigens and DNA in solid tumours.
A multiparameter flow cytometric assay for the simultaneous study of tumour associated antigens (TAA) and DNA in fresh solid tumours was devised.
Cell suspensions were prepared by disaggregating un... | 3 |
1,862 | Embolization of a giant renal arterial aneurysm.
A 49-year-old man presented with right flank pain.
Angiography revealed a giant right renal arterial aneurysm.
Giant renal arterial aneurysms are typically treated by nephrectomy.
In this patient the aneurysm was embolized successfully with multiple Gianturco-Wallace... | 13 |
783 | Intracorporeal biliary lithotripsy.
Most bile duct calculi can be removed with standard percutaneous or endoscopic techniques.
Very large stones are the most common cause for failure.
Intracorporeal lithotripsy, and EHL in particular, can be used safely in either the biliary tree or gallbladder to fragment these lar... | 5 |
2,571 | Platelet activating factor-induced clinical and histopathologic responses in atopic skin and their modification by the platelet activating factor antagonist BN52063.
The clinical and histopathologic responses to intradermal platelet-activating factor (PAF-acether) in atopic subjects, without evidence of atopic dermati... | 19 |
2,191 | Value of transesophageal echocardiography during repair of congenital heart defects.
Two-dimensional transesophageal color Doppler echocardiography was employed intraoperatively in 30 children undergoing repair of a variety of simple and complex cardiac malformations.
There were 16 female and 14 male patients, with a... | 15 |
273 | Human macrophage colony-stimulating factor induces macrophage colonies after L-phenylalanine methylester treatment of human marrow.
Macrophage-colony stimulating factor (M-CSF) has well-known effects on murine bone marrow, but its colony stimulating activity for human bone marrow is controversial.
After treatment of ... | 3 |
1,522 | Home monitoring of gonadotropin ovulation induction using the Ovarian Monitor.
The safe use of gonadotropins relies on close hormonal and/or ultrasound monitoring to assess the response to treatment, requiring multiple hospital visits.
Home monitoring with the Ovarian Monitor (St.
Michael Research Foundation, Macleo... | 12 |
1,289 | Glaucoma secondary to epithelial downgrowth and 5-fluorouracil.
Since epithelial downgrowth involves an actively proliferating intraocular tissue, it is possible that the antimetabolite 5-fluorouracil may inhibit it.
We report a case of secondary glaucoma caused by epithelial downgrowth in which filtration surgery wa... | 10 |
1,769 | Evidence for decreased coronary flow reserve in viable postischemic myocardium.
To try to unravel the complexity and heterogeneity of the "no-reflow" phenomenon and its underlying mechanisms, we studied tissue perfusion in reperfused heart muscle by using tracer microspheres in an anesthetized dog model of 90-minute c... | 13 |
614 | Studies of the porcine intestinal calcitriol receptor in pseudo-vitamin D deficiency rickets type I.
1.
Calcitriol (1,25-dihydroxyvitamin D3) concentrations in plasma of humans and pigs with pseudo-vitamin D deficiency rickets type I (PVDRI) have been reported to be significantly lower than in normal subjects and ani... | 4 |
3,209 | Postoperative hypoxemia after nonabdominal surgery: a frequent event not caused by nitrous oxide.
We tested whether anesthesia that includes nitrous oxide (N2O) results in the development of intraoperative and postoperative pulmonary complications, including hypoxemia.
We also tested whether aging contributes to the ... | 22 |
3,249 | The efficacy of methylprednisolone in reducing flap edema.
It has been suggested that systemic steroids reduce postoperative flap edema.
This has been poorly documented by several reports based on subjective clinical observations.
In an effort to provide quantitative data on methylprednisolone and edema, a flap edem... | 22 |
2,251 | Contact dermatitis from acrylate and methacrylate compounds in Lowicryl embedding media for electron microscopy.
This report is about occupational contact dermatitis found in 3 out of 6 workers of a chemistry laboratory using Lowicryl embedding media, which contain (meth)acrylate monomer mixtures of known composition.... | 16 |
2,478 | Multigenic basis for type I diabetes. Association of HRAS1 polymorphism with HLA-DR3, DQw2/DR4, DQw8.
We analyzed extended haplotypes composed of DNA loci on the short arm of chromosome 11 for segregation with insulin-dependent (type I) diabetes mellitus.
The markers for these loci are tyrosine hydroxylase, insulin, ... | 17 |
514 | Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth.
Neovascularization is critical for the growth of tumours and is a dominant feature in a variety of angiogenic diseases such as diabetic retinopathy, haemangiomas, arthritis and psoriasis.
Recognition of the potential therapeutic b... | 3 |
972 | Pentoxifylline attenuates edema formation in proteolytic enzyme-induced lung injury.
Ex vivo canine lung lobes were exposed to a pancreatic proteolytic enzyme (chymotrypsin) alone or chymotrypsin after pretreatment with a continuous infusion with pentoxifylline.
The lobes exposed to chymotrypsin gained 133 g, while t... | 7 |
1,709 | Intraoperative coronary excimer laser angioplasty: preliminary clinical experience.
Diffuse coronary artery atherosclerosis is generally recognized as a deterrent to successful revascularization if it cannot be adequately treated.
Mechanical endarterectomy can be useful, but it is not the optimal solution owing to th... | 13 |
1,376 | The use of prostaglandin F2 alpha for the prophylaxis of cyclophosphamide induced cystitis in rats.
It is well-established that cystitis is a significant cause of morbidity after cyclophosphamide administration in clinical populations.
We induced hemorrhagic cystitis in rats using cyclophosphamide and compared contro... | 11 |
3 | Effects of epinephrine on hemodynamics and oxygen metabolism in dopamine-resistant septic shock.
The hemodynamic effects of epinephrine were prospectively studied in 13 patients with septic shock who remained hypotensive after both fluid loading and dopamine.
Hemodynamic measurements were performed before and one hou... | 0 |
2,098 | Bioenergetic recovery processes of injured myocardium.
We employed cervically transplanted nonworking myocardium to simulate the condition of a heart supported by a ventricular assist device, and to investigate the bioenergetic recovery processes of injured myocardium with 31P nuclear magnetic resonance (NMR) techniqu... | 13 |
1,938 | Comparison of blood flow assessment between laser Doppler velocimetry and the hydrogen gas clearance method in ischemic intestine in dogs.
Blood flow of the colon and the ileum was measured before and after intestinal devascularization by laser Doppler velocimetry and the hydrogen gas clearance technique in 10 dogs in... | 13 |
170 | Association of disease-free survival and percent of ideal dose in adjuvant breast chemotherapy.
The relationship between percent of ideal dose and disease-free survival was examined in 256 Stage II and III patients who participated in a 2-year breast adjuvant chemotherapy trial consisting of cyclophosphamide, methotre... | 3 |
2,602 | A randomized comparison of methotrexate dose and the addition of bleomycin to CHOP therapy for diffuse large cell lymphoma and other non-Hodgkin's lymphomas. Cancer and Leukemia Group B study 7851.
In 1978, Cancer and Leukemia Group B initiated a randomized study to determine the usefulness of the addition of bleomyci... | 19 |
350 | Immunoscintigraphy of ovarian cancer with indium-111-labeled OV-TL 3 F(ab')2 monoclonal antibody.
The safety and diagnostic accuracy of immunoscintigraphy with the indium-111-labeled monoclonal antibody OV-TL 3 F(ab')2(111In-OV-TL 3 F(ab')2) for diagnosis and follow-up of ovarian cancer was prospectively studied in 31... | 3 |
1,624 | Intracoronary adenosine administration during reperfusion following 3 hours of ischemia: effects on infarct size, ventricular function, and regional myocardial blood flow.
Previous studies have demonstrated that adenosine significantly enhances myocardial salvage after 90 minutes of regional ischemia.
To determine it... | 13 |
149 | Variations in malaria transmission rates are not related to anopheline survivorship per feeding cycle.
Anopheline survivorship, vectorial capacity, and mosquito infection probability estimates from mosquito infection rates were determined 4 times in 1 year in a Papua New Guinea village.
Estimates of survivorship over... | 2 |
2,404 | Diabetic patients have abnormal cerebral autoregulation during cardiopulmonary bypass.
We tested the hypothesis that insulin-dependent diabetic patients with coronary artery bypass graft surgery experience altered coupling of cerebral blood flow and oxygen consumption.
In a study of 23 patients (11 diabetics and 12 a... | 17 |
1,845 | Effects of calcium channel blockers on coronary vasoconstriction induced by endothelin-1 in closed chest pigs.
The purpose of this study was to determine the effects of endothelin-1 on the coronary vascular bed of closed chest pigs.
Endothelin-1 (3 to 30 pmol/kg body weight) was selectively administered into the left... | 13 |
380 | Overall mortality and cancer mortality around French nuclear sites
Higher than expected mortality from leukaemia has been observed in the population under age 25 living around Sellafield and Dounreay, nuclear reprocessing plants in the United Kingdom.
We report the results of a similar study for the population resid... | 3 |
696 | Soluble interleukin-2 receptor in Crohn's disease: relation of serum concentrations to disease activity.
Serum concentrations of soluble interleukin-2 receptor (sIL-2R) were measured as a marker of immune activation in a group of 30 patients with Crohn's disease.
sIL-2R concentrations were determined by enzyme linked... | 5 |
347 | Drug-induced DNA damage and tumor chemosensitivity.
Cytotoxic drugs act principally by damaging tumor-cell DNA.
Quantitative analysis of this interaction provides a basis for understanding the biology of therapeutic cell kill as well as a rational strategy for optimizing and predicting tumor response.
Recent advance... | 3 |
297 | Medroxyprogesterone acetate lowers plasma corticotropin and cortisol but does not suppress anterior pituitary responsiveness to human corticotropin releasing factor.
The endocrine action of medroxyprogesterone acetate (MPA) has been claimed to be of a glucocorticoid-like nature.
Upon clinical observation, MPA has bee... | 3 |
2,113 | Buerger's colour.
Cyanosis of the hands and feet in Buerger's disease is known as 'Buerger's colour'.
This characteristic skin colour is produced by the subpapillary venous plexus.
The reactions of the subpapillary venous plexus in patients with Buerger's disease were observed by analysing the fractional blood volum... | 13 |
877 | Sialolithiasis: case studies and review.
Three cases of sialolithiasis are presented, each representative of acute and chronic presentations of this problem.
The evaluation and treatment of salivary gland and duct stones are outlined.
The primary axiom is, "Treat the gland, not the stone," and the essential aspects ... | 6 |
70 | Day care characteristics associated with Haemophilus influenzae disease. Haemophilus influenzae Study Group.
To identify characteristics of day care facilities associated with H.
influenzae disease, we compared 92 licensed facilities in which a case of H.
influenzae disease had occurred with randomly selected facili... | 0 |
2,293 | Psoriasis vulgaris: a genetic approach.
Evidence for a genetic contribution in psoriasis comes from direct examination of a large segment of the population in an isolated island environment, epidemiologic and questionnaire studies presented to psoriatic patients, twin studies collected from the literature and from twi... | 16 |
1,124 | Mechanism of stroke in patients taking aspirin.
During a 1-year period, we prospectively studied the mechanism and severity of stroke in 47 patients sustaining a cerebral infarction while taking aspirin.
The mechanism of stroke was undetermined in 12 patients (26%).
In the remaining 35 patients, we identified 39 pot... | 9 |
3,007 | Effects of stress on gastric mucosal prostaglandin generation in intact, adrenalectomized, and sham-operated rats.
To study the effects of (a) cold restraint stress and (b) adrenalectomy in association with cold restraint stress on gastric mucosal ulceration and prostaglandin generation, we performed two experiments.
... | 22 |
1,995 | Effects of renin inhibition in systemic hypertension.
The effect of the direct renin inhibitor enalkiren (Abbott Laboratories) was examined in 8 healthy patients with essential hypertension.
With an unrestricted sodium diet, plasma renin concentration was inhibited within 10 minutes by intravenous enalkiren and remai... | 13 |
615 | Macrophage colony stimulating factor restores in vivo bone resorption in the op/op osteopetrotic mouse.
The op/op variant of murine osteopetrosis is a recessive mutation characterized by impaired bone resorption due to lack of osteoclasts.
Cultured osteoblasts and fibroblasts from this mutant do not secrete M-CSF act... | 4 |
444 | Improving diagnostic accuracy of cervical metastases with computed tomography and magnetic resonance imaging.
Elective neck dissection in patients with head and neck cancer continues to be controversial.
The management of these patients would be greatly facilitated by improvements in predicting cervical metastases.
... | 3 |
2,256 | Localized hyperhidrosis in pretibial myxedema.
Two cases of spontaneous hyperhidrosis limited to pretibial myxedema lesions were studied.
Quantitative measurements of stimulated eccrine sweat were made after the intradermal injection of methacholine.
The sweat rate was two to four times greater in the lesional skin ... | 16 |
2,469 | Reduced beta-cell glucose transporter in new onset diabetic BB rats.
Previous studies from our laboratories have suggested a defect in glucose transport in islets isolated from BB rats on the first day of overt diabetes.
To quantitate by immunostaining the glucose transporter of beta-cells (GLUT-2) before and at the ... | 17 |
775 | Increased cholecystectomy rates in Saudi Arabia
Gallstones have become increasingly prevalent in Saudi Arabia, where cholecystectomy is now one of the commonest major abdominal operations.
2854 people underwent cholecystectomy in the 14 hospitals of the country's Eastern Province in the years 1977 to 1986.
During t... | 5 |
3,111 | Measurement of resistance versus flow in assessing efficiency of aortocoronary bypass grafts.
Measurement of flow in saphenous bypass grafts with an electromagnetic flowmeter is complicated and poorly reproducible.
Since coronary flow is largely dependent on variable factors the stable value of resistance seems more ... | 22 |
2,084 | In vitro and in vivo evaluation of intraluminal ultrasound in normal and atherosclerotic arteries.
This study evaluated the dimensional and morphologic precision of arterial images obtained using intraluminal rotating A-scan ultrasound catheters [5.0F (30 mHz) and 8.0F (20 mHz)].
Dimensions of in vitro ultrasound ima... | 13 |
2,288 | The role of antihistamines in atopic dermatitis.
Although several lines of evidence support a role for histamine in the pathogenesis of atopic dermatitis, antihistamines have generally offered only marginal therapeutic benefit.
The efficacy of the classic antihistamines has been severely limited by sedative effects, ... | 16 |
576 | Soft-tissue tumor with abnormal amianthoid collagen fibers.
Electron microscopic examination of a solitary soft-tissue tumor from the face demonstrated large areas with abnormal amianthoid collagen fibers in the neoplasm.
The lesion was classified as a benign neoplasm of myofibroblasts and tentatively named a myofibr... | 3 |
1,486 | Sodium lauryl sulfate-induced irritant contact dermatitis in vulvar and forearm skin of premenopausal and postmenopausal women.
Reactivity of the skin of the forearm and labia majora to three concentrations (2%, 3%, 5%) of sodium lauryl sulfate was studied in 20 healthy women, 10 premenopausal and 10 postmenopausal.
... | 12 |
3,016 | Red cell autoantibodies, multiple immunoglobulin classes, and autoimmune hemolysis.
The effects and interrelationships of multiple immunoglobulin coating (i.e., increased red cell [RBC]-bound IgM and/or IgA in addition to IgG) were investigated in 404 patients with warm-reactive RBC autoantibodies on 590 occasions.
M... | 22 |
510 | Haemangiosarcoma of the maxillary antrum.
Angiosarcomas are extremely rare in the head and neck and the histological diagnosis is often difficult.
We present a case of a haemangiosarcoma of the maxillary antrum in a 33 year old male.
The histological diagnosis and subsequent management are discussed.
| 3 |
141 | Humoral and cell-mediated immune responses to the Plasmodium falciparum antigens PF155/RESA and CS protein: seasonal variations in a population recently reexposed to endemic malaria.
Resurgence of falciparum malaria occurred in the Central Highlands of Madagascar in the 1980s and the disease is currently hyperendemic.... | 2 |
838 | Antibiotic use among children in an urban Brazilian slum: a risk factor for diarrhea? [published erratum appears in Am J Public Health 1991 Apr;81(4):417]
Among a cohort of children in a poor urban setting in Brazil, the relative risk for the occurrence of a new episode of diarrhea in the two weeks following antibioti... | 5 |
1,106 | Systems analysis of cerebrovascular pressure transmission: an observational study in head-injured patients.
In an observational study in head-injured patients, cerebrovascular pressure transmission was investigated using a systems analysis approach whereby the blood pressure (BP) waveform was used as a measure of an i... | 9 |
1,184 | Pharmacologic treatment of noncognitive behavioral disturbances in elderly demented patients.
Fifty-nine elderly residents of long-term care facilities who had DSM-III diagnoses of dementia were studied in an 8-week randomized, double-blind comparison trial of haloperidol, oxazepam, and diphenhydramine to test the eff... | 9 |
2,866 | The MAC scale in a normal population: the meaning of "false positives".
The MAC scale has been very successful in identifying alcoholics and, in studies of clinical populations, is often considered a test for predisposition to alcoholism.
MacAndrew, however, holds that the MAC scale assesses a more general personalit... | 20 |
2,534 | A review of iodine toxicity reports.
This article summarizes case reports, population studies, and experimental studies from the literature concerning adverse effects of exposure to iodine from the mid-1880s to 1988.
Exposure to excessive iodine through foods, dietary supplements, topical medications, and/or iodinate... | 18 |
3,030 | Reversal of colchicine-induced mitotic arrest in Chinese hamster cells with a colchicine-specific monoclonal antibody.
The ability of a high-affinity colchicine-binding monoclonal antibody to reverse the effects of colchicine on Chinese hamster ovary cells was investigated.
Using flow cytometry, a complete mitotic bl... | 22 |
2,373 | Increased preproinsulin mRNA in pancreatic islets incubated with islet cell-stimulating antibodies from serums of type I diabetic patients.
We recently described autoantibodies that stimulate the release of insulin from pancreatic beta-cells both in vitro and in vivo.
The aim of this study was to establish whether is... | 17 |
533 | Carboplatin in childhood brain tumors. A Children's Cancer Study Group Phase II trial.
Between October 1985 and March 1988, Children's Cancer Study Group institutions entered 95 patients with recurrent brain tumors into a Phase II trial of carboplatin 560 mg/m2 every 4 weeks.
Complete or partial responses were observ... | 3 |
2,906 | Skiing and snowboarding injuries. When schussing is a pain.
Downhill and cross-country skiing and snowboarding are growing rapidly in popularity.
With the ever-increasing number of participants, physicians must be prepared to deal with the injuries specific to these sports.
More important, physicians need to use epi... | 20 |
258 | Serologic determinants of survival in patients with squamous cell carcinoma of the head and neck.
Specific circulating serum proteins may reflect unique properties governing the growth and progression of head and neck cancers.
One hundred three previously untreated patients with squamous cell carcinoma of the head an... | 3 |
3,252 | Obstructive jaundice: use of expandable metal endoprosthesis for biliary drainage. Work in progress.
Expandable metal endoprostheses were implanted transhepatically in 61 patients with obstructive jaundice.
Fifty-three patients had malignant and eight had benign obstructions.
Because of the small diameter of the com... | 22 |
832 | High-fat semielemental diet in the treatment of protracted diarrhea of infancy.
The capacity for greater fat absorption relative to carbohydrate absorption in protracted diarrhea of infancy was studied in a developed and a developing country (Buffalo, NY, and Bangkok, Thailand).
Fifty patients with protracted diarrhe... | 5 |
1,964 | Intermittent claudication, heart disease risk factors, and mortality. The Whitehall Study
In the Whitehall study, 18,388 subjects aged 40-64 years completed a questionnaire on intermittent claudication.
Of these subjects, 0.8% (147) and 1% (175) were deemed to have probable intermittent claudication and possible int... | 13 |
2,691 | Serologic, biologic, and western blot analysis of a T suppressor factor with specificity for the hapten 4-hydroxy-3-nitrophenyl acetyl derived from serum-free medium.
A T cell hybridoma producing a T suppressor factor (TsF) with specificity for the hapten nitrophenyl was converted to long term growth in serum-free med... | 19 |
1,243 | Plasticity in the aging brain. Reversibility of anatomic, metabolic, and cognitive deficits in normal-pressure hydrocephalus following shunt surgery.
The course of idiopathic normal-pressure hydrocephalus was studied in a 78-year-old woman with a 4-year history of progressive dementia who underwent neuropsychologic te... | 9 |
1,302 | Treatment of idiopathic testicular failure with high-dose testosterone undecanoate: a double-blind pilot study.
The effect of high-dose (240 mg/d) intake of testosterone (T) undecanoate was studied for sperm characteristics, function of the accessory sex glands, and hormonal parameters of men with idiopathic oligozoos... | 11 |
2,886 | Overcoming potential pitfalls in the use of Medicare data for epidemiologic research.
We used Medicare data bases and US Census data to address two questions critical to the use of Medicare files for epidemiologic research.
First, we examined the degree to which the population enrolled in the Medicare program is simi... | 20 |
1,438 | Suppression of immunoglobulin and interleukin-6 production from peripheral blood mononuclear cells by dialysis membranes.
The influence of dialysis membranes on immunoglobulin and interleukin-6 production was estimated in vitro.
Peripheral blood mononuclear cells from 11 patients undergoing hemodialysis were incubate... | 11 |
2,275 | The inhibition of NK cell function by azathioprine during the treatment of patients with rheumatoid arthritis.
Treatment with azathioprine of patients with rheumatoid arthritis leads to a dramatic reduction in the 4 h NK cytotoxicity against K562 cells.
The 24 h cytotoxicity against K562 and U937 cells, however, rema... | 16 |
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