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1,059 | Ubiquitin immunoreactivity in kuru plaques in Creutzfeldt-Jakob disease.
Cerebellar kuru plaques in 2 cases of Creutzfeldt-Jakob disease were studied immunohistochemically.
Similar to cerebellar senile plaques in Alzheimer's disease, many kuru plaques contained ubiquitin-positive, tau-negative small granular elements... | 9 |
736 | Surgical aspects of sclerosing cholangitis. Results in 178 patients.
Of 178 patients with sclerosing cholangitis treated since 1950, 88 patients had associated inflammatory bowel disease, 72 had no such history, and 18 had iatrogenic injury or stone disease.
A total of 233 biliary operations were performed, with a 75... | 5 |
973 | Prototype volume-controlled resuscitator for neonates and infants.
Twenty-five infants receiving assisted ventilation in an ICU were manually ventilated for 5-min periods using either a new prototype volume-controlled resuscitator (VCR) or a standard self-inflating resuscitator (SIR).
Variables monitored during these... | 7 |
1,053 | Depression in dementia of the Alzheimer type and in multi-infarct dementia.
The authors used the Hamilton Rating Scale for Depression and a rating of depressed mood to investigate the prevalence of depression in 55 patients with Alzheimer's disease, 37 patients with multi-infarct dementia, and 30 nondemented compariso... | 9 |
1,262 | Evaluation of visual fields by ophthalmologists and by OCTOSMART program.
The introduction of Goldmann perimetry standardized measuring conditions as much as possible.
In spite of this, it had been possible for the perimetrist to influence the results of perimeter measurements.
The introduction of computer-controlle... | 10 |
3,092 | Measuring crackles.
Crackles heard on auscultation can be represented graphically as a time-amplitude plot of the associated waveform.
To assess the relative merits of several measures which might be considered for machine implementation in diagnostic instruments, we compared the reproducibility of those based on the... | 22 |
2,904 | Unintended injuries in children: the French situation.
The French situation with respect to mortality from unintentional injuries in children is far from satisfactory.
International comparison is made difficult by statistical bias, but although excess injury mortality is decreasing in France, rates are higher than in... | 20 |
3,167 | Postinduction repression of the beta-interferon gene is mediated through two positive regulatory domains.
Virus induction of the human beta-interferon (beta-IFN) gene results in an increase in the rate of beta-IFN mRNA synthesis, followed by a rapid postinduction decrease.
In this paper, we show that two beta-IFN pro... | 22 |
2,264 | Basophil histamine release and airway response to mite allergen in atopic dermatitis.
Twelve patients with atopic dermatitis (AD) were subjected to in vitro histamine release from peripheral blood leukocytes (basophils) and in vivo bronchial inhalation challenge using house dust mite (Dermatophagoides farinae) allerge... | 16 |
2,554 | Rearrangement of immunoglobulin, T-cell receptor, and bcl-2 genes in malignant lymphomas in Hong Kong.
The pattern of malignant lymphomas in the Hong Kong Chinese population is characterized by a low incidence of Hodgkin's disease and follicular lymphomas.
The authors studied the immunoglobulin (Ig), T-cell receptor ... | 19 |
2,490 | Depletion of alcohol (hexanol) dehydrogenase activity in the epidermis and jejunal mucosa in Sjogren-Larsson syndrome.
Using a histochemical technique, we have demonstrated a consistent deficiency of alcohol (hexanol) dehydrogenase activity within the epidermis and jejunal mucosa of patients with Sjogren-Larsson syndr... | 17 |
1,465 | A progesterone-induced blocking factor corrects high resorption rates in mice treated with antiprogesterone.
Earlier we showed that because of the presence of functional progesterone receptors, lymphocytes of healthy pregnant women produced an immunomodulatory protein in the presence of progesterone, whereas those of ... | 12 |
3,005 | Problem solving in implant dentistry.
Dental implants have become an accepted form of dental care, with reported functional 5-year success rates of 90% and higher.
These impressive statistics include, but do not identify, the problems that may have been created by clinical ineptitude.
Diagnostic acumen and preventiv... | 22 |
15 | Streptococcus mitis sepsis in bone marrow transplant patients receiving oral antimicrobial prophylaxis.
PURPOSE: Streptococcal infection has increasingly become a problem in neutropenic patients.
We report on an outbreak of Streptococcus mitis sepsis in six bone marrow transplant patients receiving oral antimicrobial... | 0 |
2,085 | Stunned myocardium during extracorporeal membrane oxygenation.
The "stunned myocardium" is a syndrome of reversible myocardial dysfunction that may be mediated by oxygen-derived free radicals.
This phenomenon has been seen in some neonates undergoing extracorporeal membrane oxygenation.
We performed echocardiograms ... | 13 |
502 | Embryologic fusion planes and the spread of cutaneous carcinoma: a review and reassessment.
It has long been held that embryologic fusion planes influence the spread of skin cancer.
Embryologic fusion planes have been implicated in the depth of invasion, horizontal spread, and recurrence of cutaneous carcinoma.
Howe... | 3 |
2,968 | Pulmonary circulation and burns and trauma.
The lung is a critical organ in victims of thermal injury or multiple trauma since the blood that drains injured organs circulates through the pulmonary circulation before passing through any other organ.
The lung therefore will receive the first volley of cytotoxins releas... | 20 |
920 | Bronchial cartilage alterations in lung transplantation.
Changes in the hyaline cartilage of the proximal bronchial tree were investigated in a group of combined heart-lung and double-lung recipients with and without OB.
Ossification, calcification and fibrovascular ingrowth into the normally avascular hyaline bronch... | 7 |
1,239 | Failure of nine-month phenobarbital administration to reverse amygdaloid-kindled seizure susceptibility in cats.
Upon completion of left amygdaloid kindling, 4 cats underwent long-term phenobarbital administration during the subsequent 5- to 9-month rest period.
Plasma phenobarbital levels were maintained above 15 to... | 9 |
1,214 | Deteriorating ischemic stroke: risk factors and prognosis.
To determine a risk profile of deterioration in cerebral infarction of less than 8 hours' duration, we studied prospectively a series of clinical and radiologic data in 98 patients.
We evaluated the Canadian Neurological Scale Score and Barthel index during a... | 9 |
499 | Clinical application of ras gene mutation for diagnosis of pancreatic adenocarcinoma.
Most pancreatic adenocarcinomas are known to have ras gene (oncogene) mutations.
The site of the mutations is localized in codon 12 of K-ras gene.
Such high incidence and localization of the ras gene mutations have not been observe... | 3 |
3,003 | Blood loss reduced during hip arthroplasty by lumbar plexus block.
We measured the blood loss during and after hip replacement in two groups of women, each consisting of 10 patients.
In one group the lumbar plexus was infiltrated with bupivacaine, in the other it was not.
The group in whom the plexus was blocked had... | 22 |
3,013 | The use of the Jarvik-7 total artificial heart and the Symbion ventricular assist device as a bridge to transplantation.
The proliferation of transplantation programs has not been paralleled by a similar increase in the availability of organ donors.
Between 1984 and 1987, 104 orthotopic heart transplantations were pe... | 22 |
349 | Antigen related to cell proliferation in malignant gliomas recognized by a human monoclonal antibody.
A human monoclonal antibody (CLN-IgG) was produced from a human-human hybridoma derived from lymphocytes of a patient with cervical carcinoma.
The reactivities of this antibody with various human glioma tissues and c... | 3 |
89 | Accuracy in early prediction of prognosis of patients with septic shock by analysis of simple indices: prospective study.
In 26 consecutive septic shock patients, we analyzed the clinical, hemodynamic, and metabolic data before and during volume infusion to test their circulatory reserve in response to fluid repletion... | 0 |
3,188 | Patients at risk for cardiac death late after aortic valve replacement.
A total of 100 patients aged 24 to 78 years were screened prospectively a mean of 71 months after aortic valve replacement for the presence of left ventricular hypertrophy (LVH) on the ECG (Estes scores greater than or equal to 5.0) and for repeti... | 22 |
3,154 | Maternal serum screening for aneuploid pregnancy by alpha-fetoprotein, hCG, and unconjugated estriol.
A number of serum screening protocols are either currently in use or proposed to identify pregnant women under 35 years of age who are at increased risk for a Down syndrome fetus.
It has been suggested that these sam... | 22 |
2,193 | Longitudinal results after first-stage palliation for hypoplastic left heart syndrome.
To evaluate the results of palliative surgery for hypoplastic left heart syndrome, we reviewed the records of 57 infants who underwent first-stage reconstruction at our institution between July 1983 and April 1989.
Of the 57 infant... | 15 |
1,937 | Fish oil supplementation in patients with stable claudication.
Increased blood viscosity occurs in patients with claudication.
This increase in viscosity, which is mainly due to elevated fibrinogen levels and a decreased red cell deformability, adversely influences blood flow.
In addition to a positive effect on blo... | 13 |
1,226 | Neonatal facial and cry responses to invasive and non-invasive procedures.
Evaluation of pain in neonates is difficult due to their limited means of communication.
The aim was to determine whether behavioural reactions of cry and facial activity provoked by an invasive procedure could be discriminated from responses ... | 9 |
1,450 | Intracavernous injection of prostaglandin E1 in combination with papaverine: enhanced effectiveness in comparison with papaverine plus phentolamine and prostaglandin E1 alone.
We compared the erectile response to intracavernous injection of a combination of papaverine and prostaglandin E1 with that of a combination of... | 11 |
3,094 | Association of anterior ectopic anus and partial absence of levator musculature in a woman with impaired defecation. Report of a case.
A 25-year-old nulliparous woman with adult onset constipation and slight anterior displacement of the anus underwent pelvic magnetic resonance imaging and was diagnosed with congenital... | 22 |
1,443 | Palmar keratoses in family members of individuals with bladder cancer.
A total of 270 bladder cancer cases, 178 first-degree relatives and 127 spouses of the bladder cancer cases and 329 hospital controls were studied to evaluate the association between palmar keratoses, bladder cancer and environmental and genetic fa... | 11 |
107 | Patterns of bacterial infection in calves implanted with artificial hearts.
Device-related infection is one of the most serious potential consequences of total artificial heart (TAH) implantation.
This complication must be addressed before the full potential benefit of these devices, especially fully implantable devi... | 0 |
3,260 | Three-year outcomes for maintenance therapies in recurrent depression.
We conducted a randomized 3-year maintenance trial in 128 patients with recurrent depression who had responded to combined short-term and continuation treatment with imipramine hydrochloride and interpersonal psychotherapy.
A five-cell design was ... | 22 |
1,546 | Left and right ventricular flows by Doppler echocardiography: serial measurements in patients with aortic regurgitation during exercise, cold pressor stimulation, and vasodilation.
To test the practicality of Doppler echocardiography to measure serial change, biventricular outputs were measured in 15 patients with aor... | 13 |
220 | Breast cancer during pregnancy and lactation.
Breast cancer is the most frequently seen cancer in pregnancy and lactation, but the incidence is low, the disease being seen in approximately 0.03% of pregnancies.
Only 1% to 2% of breast cancer overall is diagnosed during pregnancy or lactation.
There is no evidence to... | 3 |
1,043 | Increased serotoninergic and noradrenergic activity in hepatic encephalopathy in rats with thioacetamide-induced acute liver failure.
Functional changes of various neurotransmitter systems have been implicated in the pathogenesis of hepatic encephalopathy.
In this study the role of brain monoaminergic neurotransmitte... | 9 |
1,636 | Sensitivity of a set of myocardial infarction screening criteria in patients with anatomically documented single and multiple infarcts.
A subset of 3 screening criteria (Q wave greater than or equal to 30 ms in lead aVF, any Q or R wave less than or equal to 10 ms and less than or equal to 0.1 mV in lead V2, and R wav... | 13 |
755 | Sphincter of Oddi manometry: decreased risk of clinical pancreatitis with use of a modified aspirating catheter.
This study was undertaken to determine whether routine use of a modified triple-lumen five French sphincter of Oddi manometry catheter would reduce the frequency and severity of post-manometry pancreatitis ... | 5 |
2,274 | Anaesthetic management of systemic mastocytosis.
Systemic mastocytosis is an uncommon disorder of mast cell proliferation in connective tissues.
Mast cell degranulation may occur on exposure to various stimuli and drugs.
The release of histamine, heparin and vasoactive substances such as prostaglandin D2 may cause s... | 16 |
1,067 | Racial differences in the anterior circulation in cerebrovascular disease. How much can be explained by risk factors?
The entry characteristics of 1367 patients enrolled into the Extracranial/Intracranial Bypass Study were examined to determine if site differences in intracranial and extracranial arterial lesions amon... | 9 |
2,023 | Brief angiotensin converting enzyme inhibitor treatment in young spontaneously hypertensive rats reduces blood pressure long-term
Our study examines the long-term cardiovascular effects after a brief period of angiotensin converting enzyme (ACE) inhibitor treatment in young spontaneously hypertensive rats (SHR).
SHR... | 13 |
2,512 | Tests of thyroid function: update in the diagnosis and management of thyroid disease.
Current thyroid function tests give the clinician powerful tools for the accurate assessment of thyroid status in the majority of patients encountered.
There are, however, a small number of clinical situations in which there appear ... | 18 |
1,722 | Critical care transportation medicine: new concepts in pretransport stabilization of the critically ill patient.
Regionalization of health care for trauma has become commonplace, and the same concept for critically ill medical/surgical patients is developing.
Recent evidence suggests that current stabilization measur... | 13 |
1,484 | Comparative study of the changes in insulin-like growth factor-I, procollagen-III N-terminal extension peptide, bone Gla-protein, and bone mineral content in children with Turner's syndrome treated with recombinant growth hormone.
Six girls (7-13 yr old) with Turner's syndrome and short stature were treated for 1 yr w... | 12 |
1,034 | Excitatory amino acids in the developing brain: ontogeny, plasticity, and excitotoxicity.
Besides their role as neurotransmitters, excitatory amino acids (EAAs) in the developing brain are crucially involved in plasticity and excitotoxicity which are modified by their distinct ontogeny.
Along with incomplete neuritog... | 9 |
1,162 | Skin conductance and arousal in the newborn.
We measured skin conductance continuously from the sole of a foot in babies of different conceptional ages before, during, and for 10 minutes after a 'heel prick' carried out for routine blood sampling.
We studied 82 healthy babies whose gestational and postnatal ages rang... | 9 |
1,009 | Sensorineural hearing loss in bullous myringitis. A prospective study of eighteen patients.
Eighteen patients were seen over a period of 3 years.
Twenty of their ears were diagnosed as having bullous myringitis.
Pure tone audiograms and stapedial reflexes were performed within 48 h of referral.
Six ears demonstrate... | 8 |
371 | Prospective study of estrogen replacement therapy and risk of breast cancer in postmenopausal women [published erratum appears in JAMA 1991 Apr 10;265(14):1828]
We prospectively examined the use of estrogen replacement therapy in relation to breast cancer incidence in a cohort of women 30 to 55 years of age in 1976.
... | 3 |
2,378 | Biochemical studies of RT6 alloantigens in BB/Wor and normal rats. Evidence for intact unexpressed RT6a structural gene in diabetes-prone BB rats.
Lymphocytes bearing the T-lymphocyte differentiation antigen RT6 play an important immunoregulatory role in the development of autoimmune diabetes in BB rats.
Immunofluore... | 17 |
2,277 | Treatment of idiopathic guttate hypomelanosis with liquid nitrogen: light and electron microscopic studies.
Idiopathic guttate hypomelanosis is a common skin disorder of unknown cause.
Our studies have shown that significantly fewer dopa-positive melanocytes are in the white macules of idiopathic guttate hypomelanosi... | 16 |
1,082 | An implantable neurocybernetic prosthesis system.
The neurocybernetic prosthesis (Cyberonics, Inc.) is an implantable, multiprogrammable pulse generator that delivers constant current electrical signals to the vagus nerve for the purpose of reducing the frequency and/or severity of epileptic seizures.
The device is i... | 9 |
1,638 | Functional significance of myocardial perfusion defects induced by dipyridamole using thallium-201 single-photon emission computed tomography and two-dimensional echocardiography.
The mechanisms responsible for inhomogeneous myocardial blood flow after oral administration of a large dose (300 mg) of dipyridamole were ... | 13 |
2,132 | A specific in vitro bioassay for measuring erythropoietin levels in human serum and plasma.
The accurate measurement of biologically active erythropoietin (Ep) in human serum and plasma using present in vivo and in vitro bioassays is difficult because of the presence of both inhibitors and non-Ep stimulators of erythr... | 14 |
797 | A combined electromyographic and cineradiologic investigation in patients with defecation disorders.
Records from 20 patients on whom defecography and electromyography were performed simultaneously because of defecation disorders were analyzed.
According to the electromyographic investigation, the patients could be d... | 5 |
1,102 | Untying the gordian knot: the genetics of Tourette syndrome.
A review of the current status of the genetics of Tourette syndrome is presented.
Over the course of the 104 years since Gilles de la Tourette described the syndrome that bears his name, a body of carefully collected, described, and analyzed data has produc... | 9 |
1,429 | Modulation of peritoneal macrophage antimicrobial activity by peritoneal dialysis fluid, Ca++, and 1,25(OH)2D3 in CAPD patients.
Previous in vitro studies showed that Ca++ and 1,25(OH)2D3 modulate peritoneal macrophage (PM0) antimicrobial activity in CAPD patients.
Twenty-four CAPD patients were evaluated in vivo (12... | 11 |
2,174 | Elevated serum procollagen III aminopeptide levels in sarcoidosis.
Procollagen III aminopeptide (P-III-P), a peptide released during the conversion of type III procollagen to type III collagen, is considered a potential marker of fibroblast activity in a variety of pulmonary and extrapulmonary diseases.
The aim of th... | 14 |
2,770 | The natural history of alcohol abuse: implications for definitions of alcohol use disorders
Is the DSM-III-R category of alcohol abuse validly differentiated from the DSM-III-R category of alcohol dependence, or is abuse primarily a mild, prodromal condition that typically deteriorates into dependence? A 4-year longi... | 20 |
1,013 | Adenoid cystic carcinoma: a comparison between CT, MR and Gd MR imaging techniques.
Nasopharyngeal carcinoma continues to be a difficult diagnostic problem in many patients.
It is well known that amongst the many and varied manifestations of this disease, a unilateral middle ear effusion in an adult should be regarde... | 8 |
1,759 | Regression of infundibular pulmonary stenosis after successful balloon pulmonary valvuloplasty in adults.
Between July 1985 and March 1988, 22 adult patients with congenital pulmonary stenosis underwent balloon pulmonary valvuloplasty.
There were 10 males and 12 females aged 16-45 (average 25 +/- 9.9) years.
All pat... | 13 |
2,669 | A novel X-linked combined immunodeficiency disease.
A novel X-linked combined immunodeficiency disease was found in five living males in an extended family in the United States.
The age of the affected males ranged from 2.5 to 34 yr.
The most prominent clinical abnormalities were a paucity of lymphoid tissue; recurr... | 19 |
1,400 | Sodium loading treatment for amphotericin B-induced nephrotoxicity.
The increased frequency and duration of antifungal treatment with amphotericin B in immunocompromised patients has stimulated a great deal of research into the mechanisms of its nephrotoxic effects and treatment modalities designed to attenuate these ... | 11 |
3,236 | Audiometric and subjective assessment of hearing handicap.
This study compares self-perceived assessment of hearing handicap with audiometrically derived measures of hearing handicap in a sample of elderly persons.
Subjects were evaluated by traditional audiometric tests, the Speech Perception in Noise test, and the ... | 22 |
962 | Glucocorticoids inhibit neurogenic plasma extravasation and prevent virus-potentiated extravasation in the rat trachea.
Capsaicin increases the permeability of blood vessels in the rat tracheal mucosa through a mechanism involving the release of tachykinins from sensory nerves.
This capsaicin-induced increase in vasc... | 7 |
1,690 | Further mapping of an ataxia-telangiectasia locus to the chromosome 11q23 region.
We recently mapped the gene for ataxia-telangiectasia group A (ATA) to chromosome 11q22-23 by linkage analysis, using the genetic markers THY1 and pYNB3.12 (D11S144).
The most likely order was cent-AT-S144-THY1.
The present paper descr... | 13 |
1,856 | Ultrasound-Doppler diagnosis of Budd-Chiari syndrome.
We report a case of apparently idiopathic Budd-Chiari syndrome, diagnosed by ultrasound and Doppler sonography, in a patient with latent myeloproliferative disease.
This case proves that Doppler sonography shows in the hepatic veins a flow pattern suggestive of pa... | 13 |
550 | Ability of circular extrachromosomal DNA molecules to carry amplified MYCN proto-oncogenes in human neuroblastomas in vivo.
Amplification of the proto-oncogene MYCN (also known as N-myc) in neuroblastomas has been shown to correlate with both disease stage and prognosis, yet little is known about the DNA structures th... | 3 |
746 | Alcoholic liver disease.
Alcoholic liver disease presents a wide spectrum of clinical manifestations ranging from mild asymptomatic fatty liver to alcoholic hepatitis and severe life-threatening liver failure with ascites, hemorrhaging esophageal varices, and encephalopathy.
Although still poorly understood, the mech... | 5 |
1,983 | Both d-cis- and l-cis-diltiazem have anti-ischemic action in the isolated, perfused working rat heart.
The effect of diltiazem (d-cis-diltiazem) on the ischemic myocardium was compared with that of l-cis-diltiazem, an optical isomer having less potent calcium channel-blocking action, in the isolated, perfused working ... | 13 |
180 | Comparison of DNA content in gastric cancer cells between primary lesions and lymph node metastases.
Cytophotomtric DNA contents of tumor cells in primary lesions and the corresponding metastatic lymph nodes were compared in 61 cases of gastric cancer to determine whether the DNA content remains stable during lymph no... | 3 |
3,344 | Development and reversibility of T lymphocyte dysfunction in experimental obstructive jaundice
This study evaluates the effect of experimental biliary obstruction by bile duct ligation (BDL) and biliary drainage on cell-mediated immunity in Wistar rats.
Immune status has been assessed by a mitogen stimulation test o... | 22 |
1,297 | The viscous fluid pump.
We describe a device useful for injection of viscoelastic material into the vitreous cavity for internal tamponade.
The instrument has proven to be reliable and "user friendly" in a clinical setting.
| 10 |
1,880 | Pharmacological reversibility of experimental cerebral vasospasm.
Using a morphometric technique, the pharmacological reversibility of luminal narrowing after experimental subarachnoid hemorrhage (SAH) was investigated.
For vasodilation, a "cocktail" consisting of 10(-4) M papaverine, 2 x 10(-4) M sodium nitroprussid... | 13 |
2,974 | Systemic amiloride inhibits experimentally induced neovascularization.
Amiloride is an inhibitor of urokinase-type plasminogen activator, and might therefore have an inhibitory effect on neovascularization.
Neovascularization was induced in rabbit corneas via local implantation of prostaglandin E1 pellets prepared in... | 21 |
1,406 | A glance at the urodynamic database.
Three hundred sixty-four patients with urinary incontinence as their presenting complaint were evaluated in the urogynecology laboratory, Department of Obstetrics and Gynecology, University of Rochester, Rochester, New York.
Of them, 226 (62%) were found to have genuine stress uri... | 11 |
2,339 | Clinical, laboratory and radiographic features in early rheumatoid arthritis.
We evaluated disease status in relation to age, sex and disease duration using some short term indices of disease activity, laboratory tests, and radiological features in 315 patients with rheumatoid arthritis of duration varying from 3 to 3... | 16 |
1,817 | Effects of angiotensin converting enzyme inhibitors and of hydralazine on endothelial function in hypertensive rats
The function of the endothelium is impaired in hypertension.
In spontaneously hypertensive rats (SHR), acetylcholine-induced relaxation is decreased and serotonin-induced constriction is increased.
Th... | 13 |
302 | Infiltration of dendritic cells in relation to tumor invasion and lymph node metastasis in human gastric cancer.
The infiltration of dendritic cells determined in 210 patients with gastric carcinoma was investigated from the standpoint of tumor invasion, lymph node metastasis, and prognosis.
Dendritic cell infiltrati... | 3 |
793 | Prevention of pancreatic fistula by modified pancreaticojejunal anastomosis.
A major cause of morbidity after pancreatoduodenectomy is leakage from the pancreaticojejunal anastomosis.
To prevent this complication, we have employed mucosal stripping from the proximal jejunum prior to end-to-end anastomosis in 19 patie... | 5 |
321 | Cutaneous manifestations of postthymic T cell malignancies: description of five clinicopathologic subtypes.
This study was undertaken to identify the cutaneous manifestations among different prognostic subgroups of postthymic T cell malignancies.
Cutaneous involvement was demonstrated in 43 of 88 cases.
We recognize... | 3 |
388 | Treatment of fallopian tube carcinoma with cisplatin, doxorubicin, and cyclophosphamide.
Primary carcinoma of the fallopian tube is uncommon and is often treated using regimens active in ovarian carcinoma.
Evidence is scant that such therapies benefit patients with fallopian tube carcinoma.
Between December 1979 and... | 3 |
3,087 | A protocol for the investigation of pregnancy loss.
A protocol for the evaluation of pregnancy loss should include a maternal history, dysmorphic examination of the fetus or abortus, photographs, autopsy, chromosome studies (in most cases), and radiographic or xeroradiographic studies.
Selected cases with suspected a... | 22 |
117 | Chronic encephalitis caused by leukoencephalopathy.
As mentioned previously, both MS and PML are demyelinating conditions of the CNS and pose diagnostic difficulties in their differentiation because of similarities in their clinical findings.
However, certain features unique to each of these diseases are helpful in c... | 1 |
1,147 | Putative neuroexcitation in cerebral ischemia and brain injury.
Involvement of neuroexcitatory mechanisms in cerebral ischemia and brain injury was explored in experimental models of repetitive forebrain ischemia by temporary occlusion of carotid arteries in gerbils and cryogenic injury to the cerebral cortex in rats ... | 9 |
2,884 | Injury and disability in matched men's and women's intercollegiate sports.
Eight matched men's and women's intercollegiate varsity teams were studied prospectively for one academic year to determine the incidence of athletic injury and resulting disability.
Sports in which both men and women participated in a compara... | 20 |
77 | Seroprevalence of Helicobacter pylori in Seventh-Day Adventists and other groups in Maryland. Lack of association with diet.
To evaluate the possible role of diet in the transmission of Helicobacter pylori, we compared H pylori seroprevalence among Seventh-Day Adventists (who are vegetarian and abstain from alcohol, c... | 0 |
1,416 | The role of ifosfamide plus cisplatin-based chemotherapy as salvage therapy for patients with refractory germ cell tumors.
A prospective study of four cycles of etoposide with ifosfamide and cisplatin (VIP) chemotherapy was conducted in 42 germ cell tumor (GCT) patients who were refractory to cisplatin with etoposide/... | 11 |
8 | Itraconazole in tinea versicolor: a review.
Itraconazole, a new orally active triazole antifungal, has been tested in patients with pityriasis versicolor.
A number of studies have shown that itraconazole is effective for this mild fungal skin disease.
The total dose required for effective treatment is 1000 mg, and i... | 0 |
644 | Estrogen prophylaxis. The U.S. Preventive Services Task Force.
Recommendation: Although routine postmenopausal estrogen replacement is not recommended, estrogen therapy should be considered for asymptomatic women who are at increased risk for osteoporosis, who lack known contraindications and who have received adequat... | 4 |
511 | Laser therapy for vaginal intraepithelial neoplasia after hysterectomy.
In recent years there has been a marked increase in the number of reported cases of vaginal intraepithelial neoplasia (VAIN) after hysterectomy.
Until about 10 years ago radiation or surgery had been the therapeutic modality mostly used for this ... | 3 |
1,940 | Thoracic epidural anesthesia improves global and regional left ventricular function during stress-induced myocardial ischemia in patients with coronary artery disease.
The aim of the present investigation was to study the effects of high thoracic epidural anesthesia (TEA), including the cardiac sympathetic segments, o... | 13 |
1,699 | Endogenous vasopressin supports blood pressure and prevents severe hypotension during epidural anesthesia in conscious dogs.
To evaluate whether, and to what extent, release of endogenous vasopressin supports blood pressure when efferent sympathetic drive is blocked by epidural anesthesia, the authors studied the effe... | 13 |
1,766 | Nonuniform regional deformation of the pericardium during the cardiac cycle in dogs.
We hypothesized that local contact forces between the pericardium and the heart cause regional variation in pericardial deformation during the cardiac cycle, reflecting volume changes of the underlying cardiac chambers.
To test this,... | 13 |
1,985 | The value of pulmonary artery and central venous monitoring in patients undergoing abdominal aortic reconstructive surgery: a comparative study of two selected, randomized groups.
One hundred two patients undergoing abdominal aortic reconstructive surgery were prospectively, randomly allocated to two groups, one of wh... | 13 |
1,480 | Peritoneal fluid fractions from patients with endometriosis do not promote two-cell mouse embryo growth.
Peritoneal fluid (PF) from 10 infertile patients with endometriosis, obtained during the follicular phase of the cycle during laparoscopy, did not promote two-cell mouse embryo growth to the extent observed by flui... | 12 |
1,424 | Ionic strength affects diffusive permeability to an inorganic phosphate ion of negatively charged dialysis membranes.
Electrolytes undergo electrostatic resistances in reaching membrane surfaces and passing through membrane pores when weakly charged dialysis membranes are used in hemodialysis treatments.
Diffusive pe... | 11 |
1,367 | Time-course of alterations of bladder function following acetone-induced cystitis.
Although chemical cystitis is known clinically to cause decreased bladder function, there are few experimental studies on the progression of, and recovery from chemical cystitis.
Mature male rabbits underwent intravesical instillation ... | 11 |
481 | Generation of human monoclonal antibodies against colon cancer.
Lymphocytes from regional lymph nodes of patients with colon cancer were fused with a human lymphoblastoid cell line with or without in vitro immunization.
The efficacy of these two protocols for the generation of human monoclonal antibodies against colo... | 3 |
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