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2,812 | Preventing alcohol problems: survey of Canadian medical schools.
In preparation for a national conference on medical education in the prevention of alcohol problems, a survey of conference participants was conducted.
Participants were undergraduate and postgraduate representatives from each Canadian medical school an... | 20 |
551 | Segregation analysis of breast cancer from the cancer and steroid hormone study: histologic subtypes
The segregation pattern of breast cancer in white families from the Cancer and Steroid Hormone Study was investigated.
Families were categorized into four groups based on the histologic type of breast cancer in the p... | 3 |
1,824 | Surgical treatment of aneurysm or dissection involving the ascending aorta and aortic arch, utilizing circulatory arrest and retrograde cerebral perfusion.
Recently we replaced the ascending aorta and aortic arch in 8 patients with aneurysm or dissection, using profound hypothermic circulatory arrest with retrograde c... | 13 |
205 | Campylobacter pylori interactions with gastric cell tissue culture.
Many investigators have reported that gastric mucosal biopsies of patients with chronic gastritis and peptic ulcer disease show the presence of Campylobacter pylori in a large majority of cases.
Histologic examinations of such tissues indicate a clos... | 3 |
913 | Identification of somatostatin receptors in human small cell lung carcinoma.
Biopsy specimens obtained from eight patients with lung cancer were tested for content of somatostatin receptors by autoradiography.
Somatostatin receptors were detected in two of three patients with small cell lung cancer (SCLC) but in none... | 7 |
1,921 | Frequency of myocardial indium-111 antimyosin uptake after uncomplicated coronary artery bypass grafting.
The reported incidence of myocardial damage after coronary artery bypass grafting (CABG) is highly related to the methods used.
Since indium-111 monoclonal antimyosin antibody scintigraphy has been shown to be hi... | 13 |
3,227 | Myotonic dystrophy: quantification of muscle weakness and myotonia and the effect of amitriptyline and exercise.
The purpose of this study was to quantify the degree of muscle weakness and myotonia in 12 patients with myotonic dystrophy (MD), and to quantitatively determine the effects of a four- to six-month therapeu... | 22 |
322 | Giant eccrine acrospiroma.
Four cases of large eccrine acrospiroma (three benign, one malignant) are reported.
The benign tumors involved the lower extremities of two women and one man (73 to 89 years of age).
The duration of the lesions ranged from 10 to 20 years.
The malignant tumor involved the left side of the ... | 3 |
749 | Pathogenesis of ceftriaxone-associated biliary sludge. In vitro studies of calcium-ceftriaxone binding and solubility.
Ceftriaxone, a semisynthetic third-generation cephalosporin, has recently been associated with biliary sludge formation.
Analysis of the biliary concretions induced by this agent shows a calcium salt... | 5 |
92 | Lack of association between medication use and the presence or absence of bacteriuria in elderly women.
This study was undertaken to determine if there is an association between medication use and the presence or absence of bacteriuria in elderly ambulatory women.
Of 198 women who participated in three urine culture ... | 0 |
402 | Molecular structure of a major insulin/mitogen-activated 70-kDa S6 protein kinase.
The molecular structure of a rat hepatoma 70-kDa insulin/mitogen-stimulated S6 protein kinase, obtained by molecular cloning, is compared to that of a rat homolog of the 85-kDa Xenopus S6 protein kinase alpha; both kinases were cloned f... | 3 |
169 | Teniposide (VM-26) and continuous infusion cytosine arabinoside for initial induction failure in childhood acute lymphoblastic leukemia. A Pediatric Oncology Group pilot study.
Twenty-six evaluable children with newly diagnosed acute lymphoblastic leukemia (ALL) who failed to achieve initial remission after receiving ... | 3 |
1,086 | Effects of vagal stimulation on experimentally induced seizures in rats.
Repetitive stimulation of the vagus nerve inhibits chemically induced seizures in dogs.
We report here the results and conclusions from studies designed to answer some of the immediate questions raised by this finding.
(1) Maximal stimulation o... | 9 |
2,368 | Leucine metabolism in IDDM. Role of insulin and substrate availability.
The effect of insulin on plasma amino acid concentrations and leucine metabolism was examined in 18 healthy nondiabetic young volunteers and in 7 subjects with insulin-dependent diabetes mellitus (IDDM) with the euglycemic insulin-clamp technique ... | 17 |
1,135 | Controlling stability of a complex movement system.
Human movement systems have frequently been treated as one-dimensional, single-axis, rigid bodies in order to simplify the gathering, analysis, and interpretation of data.
The problem with this approach is that the results of such assumptions often lead to conclusio... | 9 |
2,040 | The estimation of post-test probability of coronary disease following exercise testing using the sequential application of two Bayesian methods.
Recent studies have revealed that Bayesian methods to estimate post-test probability following exercise testing differ in their sensitivity and specificity across the range o... | 13 |
1,514 | Genetic and familial predisposition to eclampsia and pre-eclampsia in a defined population.
Familial predisposition and patterns of genetic inheritance of eclampsia and pre-eclampsia were investigated through three or four generations in 94 families from the homogenous island population of Iceland.
The families desce... | 12 |
1,750 | Use of computed tomographic scanning and aortography in the diagnosis of acute dissection of the thoracic aorta.
Before the introduction of computed tomographic (CT) scanning, aortography was the investigation of choice for acute aortic dissection.
Between 1978 and 1982, 24 patients were referred to the Brompton Hosp... | 13 |
2,156 | Antigenic recognition by intravenous gamma-globulin of selected bacteria isolated from throats of patients with Kawasaki syndrome.
Kawasaki syndrome (KS) or mucocutaneous lymph node syndrome is an acute febrile exanthematous illness of unknown etiology.
Therapy with intravenous gamma-globulin (IVGG) results in rapid ... | 14 |
805 | Geographic variation of inflammatory bowel disease within the United States.
One approach to learn about possible environmental risks in inflammatory bowel disease relates to studying its geographic pattern of occurrence.
The geographic variation of inflammatory bowel disease within the United States was analyzed usi... | 5 |
3,304 | Nitrous oxide antagonizes CNS stimulation by laudanosine in mice.
We have investigated whether nitrous oxide antagonizes or augments the CNS stimulant action of laudanosine in mice by comparing the mean convulsive doses (CD50 (SE] of a control group and those following pretreatment with 65% nitrous oxide in oxygen for... | 22 |
1,020 | Lasers for otosclerosis--which one if any and why.
Laboratory stapedotomy and stapedectomy revisions were performed in human temporal bones while pyroelectric wave energy analyzers and ultrasensitive thermocouples measured energy absorption at the stapes footplate and in the vestibule.
Analysis of these data shows th... | 8 |
1,374 | Flutamide in hormone-resistant prostatic cancer.
Flutamide (250 mg.
orally 3 times daily) yielded a subjective response in 5 of 25 fully evaluable patients with hormone-resistant prostatic cancer.
Four additional patients had early progression.
A 40% or greater decrease in the pre-treatment prostate specific antige... | 11 |
1,540 | Ovarian response to exogenous gonadotropins during pregnancy.
Multiple ovarian follicles were successfully induced in a patient undergoing superovulation for a gamete intrafallopian transfer (GIFT) procedure despite the presence of an undiagnosed ectopic pregnancy.
Midluteal gonadotropin releasing hormone agonist (Gn... | 12 |
520 | Extraadrenal retroperitoneal paragangliomas: natural history and response to treatment.
Extraadrenal retroperitoneal paragangliomas (RP) are uncommon tumors.
Because of their rarity, little is known of their natural history or response to treatment.
We reviewed 22 patients with RP who were seen at our center between... | 3 |
3,100 | Sincalide-aided ultrasonography of the common bile duct as a predictor of biliary obstruction determined by ERCP and biliary manometry.
Sonographically observed changes in common bile duct caliber following intravenous sincalide injection were correlated with distal common duct pathology as defined by endoscopic retro... | 22 |
1,402 | The placebo response of subfertile couples to attending a tertiary referral centre.
The objective of this study was to determine whether there was a placebo response to clinic attendance in couples with prolonged (greater than 4 years) subfertility.
From 4 to 18 years of subfertility we observed a treatment independe... | 11 |
90 | Pseudomonas aeruginosa compared with Escherichia coli produces less endotoxemia but more cardiovascular dysfunction and mortality in a canine model of septic shock.
We investigated the effects of two different Gram-negative bacteria and radiation-induced leukopenia on endotoxemia, cardiovascular abnormalities, and mor... | 0 |
309 | Prospective study of alcohol intake and large bowel cancer.
The alcohol intake of a cohort of Japanese men in Hawaii is directly and significantly related to the risk of developing rectal cancer, whether assessed on the basis of amount consumed or as a percent of total calories.
Wine and whiskey are directly related ... | 3 |
2,800 | Controlling for the severity of injuries in emergency medicine research.
The injury severity score (ISS) and age have been used retrospectively to control for trauma severity.
Other control variables such as the revised trauma score (RTS) and the TRISS method (which estimates the probability of survival for each pati... | 20 |
293 | Concomitant cisplatin chemotherapy and radiotherapy in advanced mucosal squamous cell carcinoma of the head and neck. Long-term results of the Radiation Therapy Oncology Group study 81-17.
One hundred twenty-four eligible patients with advanced mucosal squamous cell carcinoma of the head and neck were entered into a p... | 3 |
2,071 | Multiple arterial fenestrations, multiple aneurysms, and an arteriovenous malformation in a patient with subarachnoid hemorrhage.
We report the case of a 49-year-old, right-handed man with multiple vascular pathologies, including a fenestrated anterior communicating artery and middle cerebral artery, an aneurysm of th... | 13 |
2,034 | A comparison of coarctation resection and subclavian flap angioplasty using ultrasonographically monitored postocclusive reactive hyperemia
The reported relatively high incidence of early restenosis at the coarctation repair site with subclavian flap angioplasty, especially in infants less than 3 months of age, promp... | 13 |
2,945 | Early detection of myocardial contusion and its complications in patients with blunt trauma.
Myocardial contusion remains an elusive clinical entity, which consumes a disproportionate amount of scarce and expensive critical care resources for the purpose of cardiac monitoring.
This study attempts to define a group of... | 20 |
2,126 | Nisoldipine--effects on the renin-angiotensin-aldosterone system and catecholamines. Studies in normotensive and hypertensive subjects.
We have studied the effects of nisoldipine, a new calcium channel antagonist, on the renin-angiotensin-aldosterone system and on plasma catecholamines in 10 healthy volunteers and in ... | 13 |
1,208 | Motor unit discharge characteristics and short term synchrony in paraplegic humans.
Frequency of firing and regularity of discharge of human motor units, and short term synchrony between pairs of motor units, have been assessed in extensor digitorum communis (EDC) and tibialis anterior (TA) muscles in control subjects... | 9 |
3,000 | Family recovery after vascular surgery.
Twenty-one families were observed in a 3-month study to assess family coping with major vascular surgery and recovery.
Analysis of family measures data (the Family APGAR, the Family Inventory of Resource for Management, and the Family Crisis Oriented Personal Evaluation Scales)... | 22 |
2,199 | Clinical approach to prenatal detection of human structural defects.
Tremendous advances in prenatal diagnosis have allowed clinicians to recognize a variety of structural defects in the developing fetus.
Guidelines for fetal ultrasonography and an approach to fetal evaluation are outlined.
The developmental morphol... | 15 |
2,129 | Alcohol consumption and blood pressure: a comparison of native Japanese to American men.
We compared the cross-sectional association of alcohol consumption with blood pressure in 810 Japanese men (JM) living in Tokyo and 946 white men (WM) living in New York.
Mean systolic (JM and WM, p less than 0.001) and diastolic... | 13 |
779 | Diarrhea.
Diarrhea is one manifestation of GI disturbance.
Symptoms may be acute if caused by such things as infections, drug reactions, alterations in diet, heavy metal poisoning, or fecal impaction.
Chronic diarrhea is a symptom of GI diseases such as irritable bowel syndrome, lactase deficiency, cancer of the col... | 5 |
3,277 | Mechanical deficit persists during long-term muscle hypertrophy.
Hypotheses were tested that the deficit in maximum isometric force normalized to muscle cross-sectional area (i.e., specific Po, N/cm2) of hypertrophied muscle would return to control value with time and that the rate and magnitude of adaptation of speci... | 22 |
683 | Phospholipids from rat, human, and canine gastric mucosa. Composition and metabolism of molecular classes of phosphatidylcholine.
To validate a recent proposal that a phospholipid lining with a high content of dipalmitoylphosphatidylcholine may protect gastric mucosa against luminal acid, it was decided to study compo... | 5 |
1,606 | Dietary preference for sweet foods in patients with dementia
Using a telephone survey, patients with probable Alzheimer's disease (n = 31) and vascular dementia (n = 14) were compared with elderly normal controls (n = 43) in preferences for different foods.
Patients with Alzheimer's disease had a greater preference ... | 13 |
2,319 | Dermal mast cell degranulation in systemic sclerosis.
Paired biopsy samples from involved and uninvolved skin were obtained from 19 patients with generalized scleroderma (11 with early, progressive disease and 8 with late, improving disease).
Skin biopsy samples were double stained for mast cell granules and for mast... | 16 |
2,054 | Efficacy of ibopamine in the treatment of heart failure.
Loss of myocardial contractility, reflexly enhanced vasoconstriction, and neuroendocrine excitation are the pathophysiologic hallmarks of low-output heart failure.
Drugs that counter both consequences afford considerable therapeutic potential in retarding and p... | 13 |
3,064 | Reduction of postoperative morbidity following patient-controlled morphine
The present study examined the impact of two methods of pain management on recovery in 38 women undergoing hysterectomy.
One group received IV morphine in the recovery room and IM morphine on the ward on a PRN basis (PRN group).
In the other... | 22 |
400 | Introduction of nerve growth factor (NGF) receptors into a medulloblastoma cell line results in expression of high- and low-affinity NGF receptors but not NGF-mediated differentiation.
Expression of the cloned human nerve growth factor receptor (NGFR) cDNA in cell lines can generate both high- and low-affinity binding... | 3 |
2,865 | The relationship between ethanol intake and DSM-III-R alcohol dependence.
The purpose of this investigation was to quantify the relationship between ethanol consumption and DSM-III-R alcohol dependence using mathematical modeling techniques that allowed for the control of confounding and assessment of interaction.
Al... | 20 |
1,398 | In vivo human testicular function assessed with P-31 MR spectroscopy.
The clinical feasibility of assessing testicular metabolic integrity with phosphorus-31 magnetic resonance (MR) spectroscopy was investigated in six healthy volunteers and 23 patients with azoospermia.
MR spectroscopic findings were compared with s... | 11 |
2,829 | The Hymenoptera venom study. III: Safety of venom immunotherapy.
One thousand four hundred ten (44%) of the 3236 subjects in the Hymenoptera venom study accepted venom immunotherapy (VIT).
Time to maintenance averaged 95 days, and the largest number achieved maintenance (147 subjects, 10.4%) at day 56.
Ninety-two pe... | 20 |
2,810 | Early identification of alcohol problems.
A high proportion of patients seen in clinical practice have an underlying alcohol problem.
This is often difficult to detect, but failure to make the diagnosis may result in unnecessary investigations and inappropriate treatment.
Furthermore, there is now good evidence of t... | 20 |
2,656 | The AIDS-related experiences and practices of primary care physicians in Los Angeles: 1984-89.
Telephone interviews of random samples of Los Angeles primary care physicians in 1984, 1986, and 1989 obtained information about their AIDS-related practice experiences, and sexual history taking.
Data from mid-1989 reveal ... | 19 |
875 | Detection of a human intracisternal A-type retroviral particle antigenically related to HIV.
Sjogren's syndrome is an autoimmune disease that is characterized by dryness of the mouth and eyes.
The loss of salivary and lacrimal gland function is accompanied by lymphocytic infiltration.
Because similar symptoms and gl... | 6 |
2,189 | Anterior fontanel pressure and visual evoked potentials in neonates and infants undergoing profound hypothermic circulatory arrest.
To determine the effects of cardiopulmonary bypass with profound hypothermic circulatory arrest (PHCA) on anterior fontanel pressure (AFP) and visual evoked potentials (VEPs), 21 neonates... | 15 |
1,142 | Influence of amphetamine treatment on somatosensory function of the normal and infarcted rat brain.
The consequences of acute amphetamine administration on the metabolic responsiveness of the cerebral cortex to physiologic activation were studied in normal and infarcted rats.
Treated rats received a 4 mg/kg intraveno... | 9 |
2,485 | Management of hypercholesterolemia in a family practice setting.
A study was undertaken to assess physician adherence and patient compliance with the National Cholesterol Education Program guidelines for the management of newly detected hypercholesterolemia.
The study site was the Department of Family Medicine, Medic... | 17 |
22 | Beta-lactamase production and susceptibilities to amoxicillin, amoxicillin-clavulanate, ticarcillin, ticarcillin-clavulanate, cefoxitin, imipenem, and metronidazole of 320 non-Bacteroides fragilis Bacteroides isolates and 129 fusobacteria from 28 U.S. centers.
beta-Lactamase production (nitrocefin disk method) and aga... | 0 |
2,837 | Nicotine dependence: a preventable risk factor for other diseases.
Nicotine meets all critical criteria for an addictive drug.
Furthermore, there is no evidence that there would be widespread compulsive use of tobacco without nicotine.
These findings have led to consideration of the cigarette as a contaminated vehic... | 20 |
1,222 | Onset phase of spinal bupivacaine analgesia assessed quantitatively by laser stimulation.
Analgesia was assessed quantitatively at various dermatomes (C7, T8, T10, T12, L1, L3, S1) for the first 30 min after subarachnoid administration of 0.5% bupivacaine 3.5 ml.
Stimulation with 10 needles and laser stimulation coul... | 9 |
244 | Equal parental origin of chromosome 22 losses in human sporadic meningioma: no evidence for genomic imprinting.
Inactivation of tumor suppressor genes can occur either by mutation at the gene locus or by loss of part or all of the chromosome region containing the gene.
The latter is most frequently detected by DNA ma... | 3 |
2,148 | Serum concentration of soluble interleukin-2 receptor as a sensitive parameter of disease activity in sarcoidosis.
We investigated the clinical value of measuring serum concentrations of soluble IL-2R in monitoring sarcoidosis.
Serum concentrations of soluble IL-2R were measured in 70 patients with sarcoidosis.
The ... | 14 |
908 | Selection factors resulting in improved survival after surgical resection of tumors metastatic to the lungs.
From 1973 through 1987, a total of 140 patients underwent 184 operations for removal of metastatic tumors to the lungs.
The number of lesions removed ranged form one to 30.
Of the patients, 44% had solitary l... | 7 |
2,206 | Child abuse of one of a pair of twins in Japan.
A nationwide survey in Japan on child abuse and neglect revealed that 10% of the victims were products of multiple births.
None of the victims who were singletons had multiple-birth siblings, and only in a few cases were both twins abused.
The findings indicated that o... | 15 |
331 | Excision repair of pyrimidine dimers induced by simulated solar radiation in the skin of patients with basal cell carcinoma.
One prominent lesion induced in DNA by ultraviolet (UV) radiation is the cyclobutyl pyrimidine dimer formed between adjacent pyrimidines on the same DNA strand.
We investigated whether people w... | 3 |
1,093 | Dissociation between pain and autonomic disturbances in cluster headache.
The relationship between pain and autonomic disturbances in cluster headache was studied in 54 patients whose attack always recurred on the same side, and in 7 others whose attack had affected either side on different occasions.
In one of these... | 9 |
1,274 | Early intraocular pressure rise after trabeculectomy.
Intraocular pressure (IOP) was measured 4 to 6 hours after surgery and on the first postoperative day in 35 eyes of 35 consecutive patients undergoing initial trabeculectomy.
In 27 eyes, the anterior chamber was re-formed at the completion of surgery with balanced... | 10 |
788 | Effect of omeprazole and high doses of ranitidine on gastric acidity and gastroesophageal reflux in patients with moderate-severe esophagitis
Thirty to fifty percent of patients with reflux esophagitis fail to heal after treatment with conventional doses of H2-receptor antagonists, whereas omeprazole administration i... | 5 |
189 | Characterization and significance of sulfonylurea receptors.
This study describes and characterizes a putative sulfonylurea receptor.
The radioligand used was [3H]glipizide (9 Ci/mmol).
The beta-cell plasma membranes were derived from a transplantable rat insulinoma generated by subcutaneous injection of RINm5F cell... | 3 |
2,488 | Southern blood club symposium: an update on selected aspects of hemochromatosis.
Genetic epidemiology studies have indicated that hereditary hemochromatosis (HH) occurs in caucasians with a frequency of 3 to 13 per thousand.
Clinical recognition however occurs far less frequently.
The disparity is best resolved by d... | 17 |
1,132 | Pain in children.
The assessment and management of children's pain is a topic that has received a great deal of attention since the late 1970s.
Nurse researchers have played a dominant role in all areas of pediatric pain relief and likely will continue to do so.
There are currently a number of pediatric pain assessm... | 9 |
143 | Comparison of active and passive case detection of cutaneous leishmaniasis in Guatemala.
To estimate the degree to which passive case detection underestimates the true incidence of cutaneous leishmaniasis in Guatemala, we compared data from the passive surveillance system of the Guatemalan Ministry of Health with a cr... | 2 |
2,845 | Subxiphoid pericardial windows--helpful in selected cases.
There is a small group of patients who sustain multiple penetrating injuries who present with haemodynamic changes, making it difficult to clinically exclude or prove the presence of penetrating cardiac injury.
It is in this select group of patients that we f... | 20 |
344 | Phase II study of fluorouracil and recombinant interferon alfa-2a in previously untreated advanced colorectal carcinoma.
We conducted a phase II clinical trial of fluorouracil (5FU) and recombinant interferon alfa-2a (rIFN alpha-2a) in 52 previously untreated patients with bidimensionally measurable metastatic colorec... | 3 |
2,978 | A borna virus cDNA encoding a protein recognized by antibodies in humans with behavioral diseases.
Borna disease virus (BDV) causes a rare neurological disease in horses and sheep.
The virus has not been classified because neither an infectious particle nor a specific nucleic acid had been identified.
To identify th... | 21 |
2,569 | Polyclonal B cell activation in lupus-prone mice precedes and predicts the development of autoimmune disease.
Polyclonal B cell activation is an early feature of autoimmune disease in humans and mice with systemic lupus erythematosus.
The contribution of polyclonal activation to the progression of autoimmunity is unc... | 19 |
393 | E1a-dependent expression of adenovirus genes in OTF963 embryonal carcinoma cells: role of E1a-induced differentiation.
Some undifferentiated F9 embryonal carcinoma cells allow adenovirus genes to be expressed independently of the E1a oncogene normally required for their activation; this has been attributed to a cellul... | 3 |
376 | Paraneoplastic cerebellar degeneration: a clinical comparison of patients with and without Purkinje cell cytoplasmic antibodies.
In a review of 32 patients with paraneoplastic cerebellar degeneration (PCD), 16 (all of whom were women) had Purkinje cell cytoplasmic antibodies (PCAb) and 16 (8 women) did not.
Most pati... | 3 |
733 | Nonoperative management of small-bowel obstruction with endoscopic long intestinal tube placement.
Intestinal obstruction remains a major cause of morbidity and mortality in surgical patients.
We reviewed the records of 77 patients with mechanical small-bowel obstruction who were treated with endoscopically and fluor... | 5 |
2,899 | Sensory nerve evoked responses in spinal cord injury.
Previous studies have documented the presence of fibrillations, positive waves, and decreased motor evoked response amplitudes in spinal cord injury (SCI) subjects.
The purpose of this study was to further evaluate sensory nerve status in this population.
Twenty-... | 20 |
3,084 | The effect of continuous epidural analgesia on postoperative pain, rehabilitation, and duration of hospitalization in total knee arthroplasty.
Efficacies of three alternate methods of postoperative analgesia were studied in 156 patients who had total knee arthroplasty (TKA).
Forty-two of these patients received paren... | 22 |
5 | Selection of antibiotic coverage in vascular patients undergoing cystoscopy.
Bacteremic seeding of prosthetic vascular grafts represents a cause for graft infection; transurethral procedures account for one source of bacteremia.
Therefore, a prospective study of 200 patients undergoing cystoscopy was conducted to ide... | 0 |
1,754 | Pulse oximetry: a new non-invasive assessment of peripheral arterial occlusive disease.
Peripheral skin perfusion reflects the level of vascularity and viability of a limb and may help in planning the site of amputation or bypass surgery in patients with vascular disease.
This study used peripheral pulse oximetry in ... | 13 |
1,442 | Comparison of two methods for the estimation of urea kinetics and introduction of a third simplified method.
It has been claimed that computed urea kinetic (UK) modelling in hemodialysed patients, for the estimation of protein intake, leads to an overestimation of protein catabolic rate (PCR).
In the present study, t... | 11 |
1,169 | Temporoparietal cortex in aphasia. Evidence from positron emission tomography.
Forty-four aphasic patients were examined with (F18)-fluorodeoxyglucose positron emission tomography in a resting state to determine whether consistent glucose metabolic abnormalities were present.
Ninety-seven percent of subjects showed m... | 9 |
1,002 | A controlled, double-blind study of the effect of quazolast on nasal challenge with ragweed antigen.
Quazolast is a potent mediator release inhibitor as determined by in vitro and in vivo testing.
A placebo-controlled, double-blind, two-way crossover study compared the safety and efficacy of Quazolast, 400 mg bid ora... | 8 |
2,134 | Wiskott-Aldrich syndrome. A case report.
This paper presents a report on a child with Wiskott-Aldrich syndrome.
The clinical picture and laboratory findings are characteristic of this disease.
The prevailing symptoms have included recurrent respiratory and alimentary tract infections, seborrhic dermatitis-type skin ... | 14 |
921 | Bronchoalveolar lavage in liquid paraffin pneumonitis.
We evaluated cells and lipids recovered in the bronchoalveolar lavage fluid from seven patients with liquid paraffin pneumonitis.
For each patient, the BALF was whitish with oil droplets on the surface.
Alveolar macrophages contained numerous, large vacuoles tha... | 7 |
2,516 | Occurrence of type VI collagen in extracellular matrix of renal glomeruli and its increase in diabetes.
Human and bovine glomerular basement membrane (GBM) preparations, representing the extracellular matrix of the renal filtration units, were found to contain type VI collagen.
This protein was solubilized by guanidi... | 18 |
1,080 | Anatomical, physiological, and theoretical basis for the antiepileptic effect of vagus nerve stimulation.
The vagus is a mixed nerve carrying somatic and visceral afferents and efferents.
The majority of vagal nerve fibers are visceral afferents and have a wide distribution throughout the central nervous system (CNS)... | 9 |
1,894 | Left ventricular asynchrony: an indicator of regional myocardial dysfunction.
There is a marked heterogeneity of myocardial wall thickening within the left ventricle and among different individuals.
It is therefore difficult to detect regional myocardial dysfunction from absolute values of systolic wall thickening.
... | 13 |
1,062 | Electroencephalography should not be routine in the evaluation of syncope in adults
We reviewed the reports of all electroencephalograms obtained at the Nashville (Tenn) Veterans Administration Hospital from September 1987 to August 1989.
Seventy-three patients were referred for evaluation of syncope or near syncope... | 9 |
1,300 | Evaluation of new rapid office test for microalbuminuria and its comparison to fully quantitative radioimmunoassay.
A novel enzyme-linked immunosorbent assay (ELISA [Dialbumin]) for rapid office measurement of microalbuminuria was evaluated and its performance compared with that of a commercially available radioimmuno... | 11 |
1,088 | Transient hyperprolactinemia is associated with a midcycle luteinizing hormone surge.
This study demonstrates that LH surge cycles in IVF patients were associated with significantly higher serum PRL concentrations than cycles in which a spontaneous LH surge did not occur.
Our findings support the hypothesis of concom... | 9 |
2,775 | The detection of alcoholism in hospitalized schizophrenics: a comparison of the MAST and the MAC.
The Michigan Alcoholism Screening Test (MAST) and the MacAndrew Alcoholism Scale (MAC) were administered to forty-one schizophrenic inpatients also meeting DSM-III criteria for either alcohol abuse or alcohol dependence a... | 20 |
648 | Arachnoid granulation cerebrospinal fluid otorrhea.
A case report and review of the temporal bone (TB) collection in the Department of Otolaryngology at SUNY Health Science Center in Syracuse demonstrated the occurrence of arachnoid granulations (AGs) in the posterior fossa surface of the TB and their role in cerebros... | 4 |
2,879 | The role of spinal flexibility in back pain complaints within industry. A prospective study.
Commonly used clinical measurements of spinal flexibility in the sagittal and frontal planes were examined as predictors of future back pain reports within industry.
The study sample consisted of 3,020 aircraft manufacturing ... | 20 |
525 | Actin architecture of cultured human thyroid cancer cells: predictor of differentiation?
The actin cytoskeleton is important for cell structure and motility.
A disordered actin architecture has been correlated with a high metastatic potential in melanoma, fibrosarcoma, and colon cancer models.
Thyrotropin is known t... | 3 |
1,625 | Clinical significance of plasminogen activator inhibitor activity in patients with exercise-induced ischemia.
To assess the fibrinolytic system in patients with exercise-induced ischemia and its relation to ischemia and severity of coronary artery disease (CAD), 47 patients with CAD confirmed by results of coronary an... | 13 |
1,458 | Small cell neuroendocrine carcinoma of Bartholin's gland.
A small cell neuroendocrine carcinoma that arose in Bartholin's gland in a 30-year-old woman is reported.
The tumor had light, electron microscopic, and immunohistochemical features typical of pulmonary small cell carcinoma and was metastatic to inguinal lymph... | 12 |
2,773 | Murine model of ethanol-induced immunosuppression.
Alcohol abuse has been associated with an increased susceptibility to infectious diseases and certain tumors.
On the basis of these observations, an effect of ethanol on the immune system has been suggested.
We have used a mouse model system in which male C57Bl/6 mi... | 20 |
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