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1,039 | Brain protection: physiological and pharmacological considerations. Part I: The physiology of brain injury.
Ischaemia, whether focal or global in nature, produces a sequence of intracellular events leading to increased cell permeability to water and ions including Ca++.
There is a loss of cellular integrity and funct... | 9 |
2,196 | Atrial cardiomyoplasty after Fontan-type procedures.
The purpose of right atrial cardiomyoplasty is to increase atrial-pulmonary flow in patients undergoing Fontan-type procedures.
We developed two surgical techniques to bypass the right ventricle, followed by right atrial cardiomyoplasty with a stimulated latissimus... | 15 |
2,923 | Cyclosporine A for prolonging allograft survival in patients with massive burns.
Cyclosporine A (CsA) immunosuppression was used in three patients with massive burns to prolong skin allograft survival.
Cyclosporine A kinetic studies in patients with burns revealed markedly accelerated blood clearance and high variabi... | 20 |
1,125 | A case-control study of Alzheimer's disease in Australia.
We conducted a case-control study of clinically diagnosed Alzheimer's disease (AD) on 170 cases aged 52 to 96 years, and 170 controls matched for age, sex and, where possible, the general practice of origin.
Trained lay interviewers naive to the hypotheses and... | 9 |
3,349 | Analysis of base station morphine orders: assessment of supervising physician consistency.
Paramedic contact with a base station should gemerate consistent recommendations reflecting a consensus of base station physician care.
In our urban EMS system, paramedics must contact a single base station to provide morphine ... | 22 |
984 | Corticosteroids in primary tuberculosis with bronchial obstruction.
The usefulness of prednisolone in combination with the modern potent antituberculous drugs has been studied in 29 children with primary lung tuberculosis and hilar adenopathy causing bronchial obstruction.
These children were divided at random in two... | 7 |
891 | Platelet-derived growth factor in idiopathic pulmonary fibrosis.
Fibrosis is a complex process involving an inflammatory reaction, fibroblast proliferation, and abnormal accumulation of interstitial collagens.
Mononuclear cells are usually present in lung fibrosis.
Activated monocytes and macrophages in culture have... | 7 |
1,782 | Effect of tachycardia on regional function and transmural myocardial perfusion during graded coronary pressure reduction in conscious dogs
The purpose of the present study was to examine subendocardial flow and function during graded coronary pressure reduction to determine the effect of tachycardia on the lower auto... | 13 |
1,681 | Characteristics of participants at baseline in the Treatment of Mild Hypertension Study (TOMHS).
The Treatment of Mild Hypertension Study (TOMHS) is a randomized, double-blind clinical trial currently being conducted to compare the effects of nonpharmacologic therapy alone with those of 1 of 5 active drug regimens com... | 13 |
544 | Chondrolipoangioma. A cartilage-containing benign mesenchymoma of soft tissue.
The clinical and pathologic features of four cases of benign mesenchymoma in which mature cartilage represented the predominant component are reported.
The distinctive histologic feature in all four cases was a lobular proliferation of car... | 3 |
713 | Fluorescence assays to monitor membrane fusion: potential application in biliary lipid secretion and vesicle interactions.
Membrane fusion constitutes an essential, intermediate step in numerous cell biological processes, occurring for example during endocytosis, membrane recycling and exocytosis.
Also less desirable... | 5 |
367 | Validation of intermediate end points in cancer research.
Investigations using intermediate end points as cancer surrogates are quicker, smaller, and less expensive than studies that use malignancy as the end point.
We present a strategy for determining whether a given biomarker is a valid intermediate end point betw... | 3 |
1,838 | Determinants of the ventricular rate during atrial fibrillation.
Determinants of the ventricular cycle length during atrial fibrillation were examined in 52 patients.
Thirty-three patients had structural heart disease and none had an accessory atrioventricular (AV) connection.
The AV node effective and functional re... | 13 |
639 | Factors influencing the result of posterior spinal fusion in the treatment of adolescent idiopathic scoliosis.
Sixty-six consecutive patients with adolescent idiopathic scoliosis treated by posterior spinal fusion using Harrington distraction compression instrumentation were followed for a minimum of 3 years.
Initial... | 4 |
3,072 | Internal mammary artery and saphenous vein graft patency. Effects of aspirin.
As part of two Department of Veterans Affairs Cooperative Trials, we obtained angiographic patency data for internal mammary artery (IMA) and saphenous vein grafts to the left anterior descending (LAD) coronary artery at 1 year after coronar... | 22 |
185 | A newly established human osteosarcoma cell line with osteoblastic properties.
A human osteosarcoma cell line, HuO9, was established from a tumor that was heterotransplanted into athymic nude mice.
Antiserum against nude mouse spleen cells was added to the early passage cultures to eliminate the host fibroblastic cel... | 3 |
2,576 | HIV disease: a review for the family physician. Part I. Evaluation and conventional therapy.
Family physicians will be challenged with caring for increasing numbers of patients infected with human immunodeficiency virus.
After confirming the presence of the infection, the physician must follow a logical sequence of e... | 19 |
1,835 | Simultaneous transesophageal atrial pacing and transesophageal two-dimensional echocardiography: a new method of stress echocardiography
The diagnostic use of exercise echocardiography has been widely reported.
However, transthoracic exercise echocardiography is inadequate in up to 20% of patients because of poor im... | 13 |
3,009 | Rhodopsin mutants that bind but fail to activate transducin.
Rhodopsin is a member of a family of receptors that contain seven transmembrane helices and are coupled to G proteins.
The nature of the interactions between rhodopsin mutants and the G protein, transduction (Gt), was investigated by flash photolysis in ord... | 22 |
1,704 | Coronary artery dissection--a case report.
Coronary artery dissection, both spontaneous and catheter-induced, is associated with a significant morbidity and mortality.
The authors present a case of a middle-aged woman with spontaneous right coronary artery dissection causing inferior wall myocardial infarction and le... | 13 |
3,160 | Early magnetic resonance imaging in acute traumatic internuclear ophthalmoplegia.
Adduction deficiency following acute head trauma may result not only from orbital damage but also from internuclear ophthalmoplegia, and in most instances this resolves over weeks to months.
To date, noninvasive imaging studies during t... | 22 |
465 | Colorectal tumors: an in vitro study of high-resolution MR imaging.
To study the potential utility of magnetic resonance (MR) imaging in staging colorectal tumors, 15 resected colonic segments containing 17 elevated lesions were examined on a 1.5- or 1.9-T superconductive MR system.
The whole intestinal wall was appa... | 3 |
3,127 | Delayed facial palsy following uncomplicated stapedectomy.
We report six cases of partial lower motor neurone facial palsy occurring between four and ten days after uncomplicated stapedectomy.
The aetiology is unclear but recovery was rapid and complete in all patients.
| 22 |
988 | Rising mortality from cryptogenic fibrosing alveolitis.
OBJECTIVE--To determine the pattern of mortality ascribed to cryptogenic fibrosing alveolitis and to identify factors that might be important in the aetiology of the disease; and to assess the validity of death certification of the disease.
DESIGN--A retrospecti... | 7 |
1,585 | Current results of elective aortic reconstruction for aneurysmal and occlusive disease.
Decisions to resect small aortic aneurysms or employ non-operative treatment for aorto-iliac occlusive disease must depend on current rather than historical surgical results.
To assess current morbidity and mortality, we reviewed ... | 13 |
1,269 | Lateral wall advancement in orbital decompression.
Treatment of dysthyroid orbitopathy can be enhanced with a modified craniofacial approach using a lateral wall osteotomy, and anterolateral advancement and osteosynthesis in conjunction with medial and inferior wall orbital decompression.
The technique of lateral wal... | 10 |
2,785 | Whole-bowel irrigation as treatment for zinc sulfate overdose.
A 16-year-old boy ingested approximately 50 zinc sulfate tablets (ZnSO4; 500-mg tablets).
After spontaneous emesis, ipecac-induced emesis, and orogastric lavage, an abdominal radiograph performed four hours after ingestion still demonstrated approximately... | 20 |
2,238 | The core polypeptide of cystic fibrosis tracheal mucin contains a tandem repeat structure. Evidence for a common mucin in airway and gastrointestinal tissue.
A cystic fibrosis trachea cDNA library was constructed and probed with a synthetic oligonucleotide containing a consensus sequence recently identified in human i... | 15 |
1,326 | Hemodialysis and the elderly patient: potential advantages as to quality of life, urea generation, serum creatinine, and less interdialytic weight gain.
A total of 204 patients treated by maintenance hemodialysis or continuous ambulatory peritoneal dialysis (CAPD) were studied to ascertain how advancing age influences... | 11 |
1,951 | Repair of supravalvar aortic stenosis: cardiovascular morphometric and hemodynamic results.
Supravalvar aortic stenosis is associated with normal systolic pressure in the aorta and its branches with the singular exception of the coronary arteries, which are hypertensive.
This uncommon lesion has been treated by patch... | 13 |
1,017 | Myogenic influences on the electrical auditory brainstem response (EABR) in humans.
Two cases demonstrating the effects of myogenic artifact on the electrical auditory brainstem response (EABR) when using a promontory stimulation site are presented.
Intensity-response functions were obtained in the unparalyzed condit... | 8 |
924 | Hydraulic conductivity of canine parietal pleura in vivo.
The hydraulic conductivity (Lp) of the parietal pleura was measured in vivo in spontaneously breathing anesthetized dogs in either the supine (n = 8) or the prone (n = 7) position and in an excised portion of the chest wall in which the pleura and its adjacent ... | 7 |
2,200 | Teratogenically induced fetal anomalies.
A variety of infectious and physical agents, maternal diseases and altered metabolic states, and drugs and chemicals have been shown to cause postnatal structural or functional disabilities when embryonic or fetal exposure occurs during human pregnancy.
These disabilities are ... | 15 |
2,830 | Unusual type of foreign body in the maxillary sinus.
A broken end of the spear presenting as a foreign body in the nasopharynx and right maxillary sinus in a 19-year-old Papua New Guinean is described.
The types of foreign bodies and their mechanisms of introduction into this site are summarized.
| 20 |
2,059 | Possible triggering of paroxysmal atrial fibrillation in normal hearts by psychological stressors: a report of two cases.
Paroxysmal atrial fibrillation was triggered by psychological stress in two patients, both of whom had normal echocardiograms and coronary angiography.
Neither patient was alcoholic or had ingeste... | 13 |
1,112 | Auditory-evoked responses in benign intracranial hypertension syndrome.
In this study, auditory brainstem-evoked responses were conducted on 28 patients with otologic symptoms (pulsatile tinnitus, hearing loss, aural fullness) secondary to benign intracranial hypertension syndrome.
Abnormalities consisting mainly of ... | 9 |
472 | Trends in conserving treatment of invasive carcinoma of the breast in females.
This population-based study presents trends in the treatment of node-negative invasive carcinoma of the breast in females during the 1980s in the Detroit metropolitan area.
It was done to determine whether or not there has been a significa... | 3 |
1,684 | Acebutolol effects on lipid profile [published erratum appears in Am J Cardiol 1990 Dec 1;66(19):A8]
The relation between lipid profile and the incidence of coronary artery disease has been confirmed by the results of epidemiologic and intervention studies.
Among antihypertensive agents, beta blockers, particularly t... | 13 |
2,611 | Computer assisted selection and assessment of antibodies in the diagnosis of lymphomas.
With increasing numbers of reagents the problem of selecting appropriate antibodies to solve problems in the diagnosis of lymphoma is becoming more complex.
One approach is to use a computer program to optimise the selection proce... | 19 |
609 | A clinical epidemiological study in low back pain. Description of two clinical syndromes.
In 100 patients with mainly chronic low back pain (LBP) signs and symptoms were evaluated prospectively and without preconceived expectation of particular findings.
Two clinical syndromes were distinguished, both characterized b... | 4 |
986 | Effect of oral omeprazole on intragastric pH and volume in women undergoing elective caesarean section
We have studied in obstetric patients the efficacy of omeprazole in increasing intragastric pH to more than 2.5 and reducing volume to less than 25 ml.
Omeprazole 40 mg was given orally the night before and again o... | 7 |
3,090 | Myocardial revascularization for the third time. Clinical characteristics and follow-up.
Twenty-five patients presenting for a third revascularization procedure were retrospectively reviewed at Loyola University Medical Center, Maywood, IL.
This represents 0.5 percent of the total revascularization cases over a five-... | 22 |
2,553 | Coordinate secretion of interleukin-1 beta and granulocyte-macrophage colony-stimulating factor by the blast cells of acute myeloblastic leukemia: role of interleukin-1 as an endogenous inducer.
Acute myeloblastic leukemia (AML) blasts have been shown to produce a variety of cytokines in culture such as interleukin-1 ... | 19 |
2,252 | Aging and the skin: recognizing and managing common disorders.
Senescent changes in structure and function of the skin and chronic solar radiation damage predispose the skin of the elderly to certain inflammatory and infectious diseases.
In this context, the diagnosis and treatment of senile xerosis and pruritus are ... | 16 |
1,040 | Myasthenia gravis.
Myasthenia Gravis is a disorder of neuromuscular function resulting from an immunologically based premature destruction of acetylcholine receptors.
The disease is characterized clinically by variable weakness accentuated by repetitive muscular activity and usually responding to the administration o... | 9 |
3,002 | Effects of endotracheal suctioning on mixed venous oxygen saturation and heart rate in critically ill adults.
The purpose of this multisite study was to determine the effects of endotracheal suctioning on mixed venous oxygen saturation (SvO2) and heart rate in 189 critically ill adults.
One-pass, intermittent suction... | 22 |
1,471 | Diagnosis of ectopic pregnancy by vaginal ultrasonography in combination with a discriminatory serum hCG level of 1000 IU/l (IRP)
The diagnostic value of vaginal sonography in combination with a discriminatory serum hCG level of 1000 iu/l (International Reference Preparation) was tested prospectively in 200 pregnant ... | 12 |
458 | 585 nm for the treatment of port-wine stains.
Although the flashlamp-pulsed-dye laser has been successfully used for the treatment of port-wine stains (PWS) at 577 nm, a number of adult patients had incomplete clearance of their birthmarks with this treatment modality because of residual vessels lying beyond the 0.75-... | 3 |
2,764 | Identification of the driver in two-rider motorcycle accidents. Inguinal contusion-laceration as an indication of the driver.
In motorcycle accidents involving two riders, medicolegal identification of the driver is necessary when one or both riders die.
It is particularly important in the latter case, because the su... | 20 |
1,990 | The role of preoperative radionuclide ventriculography in defining outcome after revascularization of the extremity.
Revascularization of the extremity was performed upon 110 patients after preoperative radionuclide ventriculography (RNVG).
Mean ejection fraction (EF) was 50 +/- 13 per cent.
Ventricular wall motion ... | 13 |
2 | Effect of blood transfusion on oxygen consumption in pediatric septic shock.
Treatment plans for pediatric septic shock advocate increasing oxygen consumption (VO2).
Recent studies in septic shock indicate that improving oxygen delivery (DO2) by increasing blood flow will increase VO2.
We prospectively examined the ... | 0 |
10 | Treatment of oral candidosis with itraconazole: a review.
Oral candidosis is a common infection in infants, elderly persons, patients receiving immunosuppressive therapy, and patients with acquired immunodeficiency syndrome (AIDS).
The orally active antifungal agent itraconazole has been evaluated in a number of diff... | 0 |
364 | Reduction of the membrane fluidity of human breast cancer cells by tamoxifen and 17 beta-estradiol.
The intracellular steady-state levels of methotrexate were previously shown to be reduced in estrogen receptor (ER)-negative human breast cancer MDA-MB-436 cells and ER-positive human breast cancer MCF7 cells following ... | 3 |
2,851 | Case management in addictions treatment.
The need for case management in addictions treatment systems has been recognized for at least 10 years.
As more attention is paid to developing this treatment component and as more data are available concerning the implementation of case management in addictions, it is becomin... | 20 |
2,759 | Subxiphoid pericardiotomy versus echocardiography: a prospective evaluation of the diagnosis of occult penetrating cardiac injury.
Diagnostic subxiphoid pericardiotomy (SP) is presently advocated for the diagnosis of occult cardiac injuries in patients with stable vital signs with juxta-cardiac-penetrating chest wound... | 20 |
267 | Tumor of the atrioventricular nodal region. A clinical and immunohistochemical study.
Autopsy specimens of 17 tumors of the atrioventricular nodal region were studied.
Sudden death occurred in 14 children and adults; seven of these patients had a history of atrioventricular block or syncope.
Three tumors were incide... | 3 |
271 | Human basophils express interleukin-4 receptors.
Interleukin-4 (IL-4), a multipotential lymphokine reputed to play an important role in the regulation of immune responses, interacts with a variety of hemopoietic target cells through specific cell surface membrane receptors.
The present study was designed to investiga... | 3 |
1,671 | Comparison of direct and indirect measures of systemic arterial pressure during weightlifting in coronary artery disease.
Based on auscultation measurements after exercise, circuit weight training in cardiac patients has been reported to provoke minimal increases in systolic pressure.
Direct (brachial artery catheter... | 13 |
1,948 | Selection of patients with acute myocardial infarction for thrombolytic therapy
PURPOSE: To critically review the current recommendations regarding the eligibility of patients with myocardial infarction for thrombolytic therapy.
DATA IDENTIFICATION: Relevant studies published from January 1980 to January 1990 were i... | 13 |
2,784 | Interaction between whole-bowel irrigation solution and activated charcoal: implications for the treatment of toxic ingestions.
STUDY OBJECTIVES: The purpose of this study was to address the issues of safety and efficacy of combining whole-bowel irrigation and activated charcoal administration for the treatment of tox... | 20 |
994 | Methacholine responsiveness among working populations. Relationship to smoking and airway caliber.
It has been suggested that the development of bronchial hyperresponsiveness (BHR) in some smokers may be an intermediate event in the progression to chronic obstructive pulmonary disease in this group.
If this is true, ... | 7 |
1,418 | Shortening of the hemodialysis procedure and mortality in "healthy" dialysis patients.
The influence of shortening chronic hemodialysis on mortality was studied by following cumulative survival in "ideal" nondiabetic dialysis patients, who had no other diseases besides their renal disease when beginning dialysis.
It ... | 11 |
2,455 | Continuous glucose for treatment of patients with type 1 glycogen-storage disease: comparison of the effects of dextrose and uncooked cornstarch on biochemical variables.
Responses to uncooked cornstarch (UCS), dextrose (Dex), and a 3:1 mixture (UCS:Dex) were determined in seven children with type 1 glycogen-storage d... | 17 |
649 | The American College of Rheumatology criteria for the classification and reporting of osteoarthritis of the hand.
Clinical criteria for the classification of symptomatic idiopathic (primary) osteoarthritis (OA) of the hands were developed from data collected in a multicenter study.
Patients with OA were compared with... | 4 |
1,096 | Fluctuation in timing of upper airway and chest wall inspiratory muscle activity in obstructive sleep apnea.
An imbalance in the amplitude of electrical activity of the upper airway and chest wall inspiratory muscles is associated with both collapse and reopening of the upper airway in obstructive sleep apnea (OSA).
... | 9 |
1,801 | The antihypertensive efficacy of hydrochlorothiazide is not prostacyclin dependent.
We tested the hypothesis that vascular prostacyclin synthesis is stimulated by hydrochlorothiazide and could account for some of the drug's antihypertensive effect.
We studied 13 patients with mild essential hypertension in a randomiz... | 13 |
133 | Isolation of human T-cell lymphotropic virus type 2 from Guaymi Indians in Panama.
Human T-lymphotropic virus type I (HTLV-I) is associated with adult T-cell leukemia/lymphoma and with a chronic degenerative myelopathy.
However, another major type of HTLV, HTLV-II, has been isolated only sporadically, and little is k... | 1 |
1,198 | Neonatal monosodium glutamate abolishes corticotropin-releasing factor-induced epileptogenic activity in rats.
Intracerebroventricular (i.c.v.) injection of rat corticotropin-releasing factor (rCRF) at doses of 5-20 micrograms in rats induces epileptogenic activity characterized by pacemaker-like spikes localized in t... | 9 |
553 | Effects of FUdR on primary-cultured colon carcinomas metastatic to the liver.
Hepatic arterial infusion of fluorodeoxyuridine (FUdR) has demonstrated efficacy in the treatment of metastatic colorectal carcinoma of the liver.
In this study, the direct cytotoxic effect of FUdR was measured on ten metastatic and two pri... | 3 |
1,776 | Blood pressure level, trend, and variability in Dunedin children. An 8-year study of a single birth cohort
In a birth cohort of children in the Dunedin Multidisciplinary Health and Development Study in New Zealand, resting blood pressures were recorded biennially five times from age 7 to 15 years.
Using previously d... | 13 |
2,538 | Antidiabetic agents.
Although either insulin or oral hypoglycemics may be used in conjunction with diet and exercise in the management of type II diabetes, drug therapy for type I diabetes involves only insulin.
C-peptide levels can be tested to assess whether the patient has remaining pancreatic endocrine function.
... | 18 |
1,180 | Metoprolol for aggressive behavior in persons with mental retardation.
Persons with mental retardation sometimes exhibit behaviors that are difficult to control.
Use of neuroleptic medications may be limited by side effects or ineffectiveness.
Beta blockers such as propranolol and metoprolol have been shown to decre... | 9 |
159 | Activated eosinophils increase vascular permeability and resistance in isolated perfused rat lungs
The effects of eosinophils activated with phorbol myristate acetate (PMA) on isolated perfused rat lungs were examined.
Eosinophils were obtained from lungs of rats infected with Toxocara canis by bronchoalveolar lavag... | 2 |
2,732 | Paradoxes in the history of the anterior cruciate ligament.
A historic review of anterior cruciate ligament (ACL) investigation reveals two important paradoxes.
(1) Ideas and concepts recently proposed were first put forth much earlier.
(2) Controversy regarding this ligament continues despite the increased amount o... | 20 |
1,246 | Aids for visual impairment.
This article provides only a flavour of the type and range of aids available to the visually impaired person.
Many other aids for leisure, learning, and daily living are illustrated in the RNIB equipment and games catalogue.
| 9 |
72 | Recombinant capsular antigen (fraction 1) from Yersinia pestis induces a protective antibody response in BALB/c mice.
Yersinia pestis produces a glycoprotein capsule, the biosynthesis of which appears to be temperature dependent.
The fraction I (F1) component of this capsule is specific to Y.
pestis and the detectio... | 0 |
2,120 | Reduction in incidence of inducible ventricular tachycardia after myocardial infarction by treatment with streptokinase during infarct evolution.
The aim of this study was to determine whether intravenous streptokinase administered with or without oral aspirin to patients with evolving myocardial infarction reduces th... | 13 |
2,835 | Screening for psychiatric and substance abuse disorders in clinical practice.
Psychiatric disorders, particularly depression and alcohol abuse, represent a large burden of illness to the society.
Many individuals with these disorders receive all of their care from health care providers who are not mental health speci... | 20 |
1,477 | Subzonal insemination for the alleviation of infertility.
Methods were developed to facilitate the use of subzonal insemination to achieve fertilization in vitro.
A clinical trial was undertaken in those patients having previously failed to achieve fertilization by in vitro fertilization, and in those presenting with... | 12 |
243 | Endoscopic ultrasonography in staging rectal cancer.
Endoscopic ultrasonography (EUS) was used to stage rectal cancer by assessing depth of invasion through bowel wall layers and/or involvement of lymph nodes.
EUS findings were correlated with histopathologic findings to discern the usefulness of this modality in pre... | 3 |
3,315 | A retroviral promoter is sufficient to convert proto-src to a transforming gene that is distinct from the src gene of Rous sarcoma virus.
The src genes of four natural isolates of avian sarcoma viruses differ from cellular proto-src in two genetic substitutions: the promoter of the cellular gene is replaced by a retro... | 22 |
1,195 | Maxillofacial surgery and nasal CPAP. A comparison of treatment for obstructive sleep apnea syndrome
Nasal continuous positive airway pressure (CPAP) is the primary therapy for obstructive sleep apnea syndrome (OSAS).
Recent reports have indicated, however, that there is a small but significant number of failures re... | 9 |
368 | Anti-idiotype monoclonal antibody carrying the internal image of ganglioside GM3.
Murine anti-idiotype monoclonal antibodies were generated against a human IgM monoclonal antibody (L612) that recognizes ganglioside GM3 on human melanoma.
Hybridomas secreting antibodies that bound specifically to L612 were selected by... | 3 |
219 | Bilateral breast cancer.
A second primary breast cancer in the opposite breast can be either synchronous or metachronous.
The majority are metachronous.
A woman who has had breast cancer has a fivefold increase in risk for a second breast cancer.
Additional risk factors include multifocal cancer, lobular carcinoma ... | 3 |
153 | Ultrasonographical investigations of onchocerciasis in Liberia.
The efficiency of ultrasonography (US) for the diagnosis and clinical characterization of onchocerciasis was evaluated.
US was performed on 120 probands in Liberia.
Ninety-two patients had generalized onchocerciasis, 21 patients suffered from the chroni... | 2 |
2,299 | The role of the immune system in the pathogenesis of psoriasis.
Psoriatic involved skin contains an increased number of activated T cells.
The mechanism through which these T cells achieve and maintain their activated state is unknown, and both antigen-dependent and -independent mechanisms may contribute.
Recently a... | 16 |
1,642 | Long-term follow-up in patients with incessant ventricular tachycardia.
Seventeen patients with coronary artery disease, idiopathic dilated cardiomyopathy or no organic heart disease who presented with incessant ventricular tachycardia (VT) were studied and followed for a mean period of 51 +/- 35 months.
In these pat... | 13 |
1,898 | ACE inhibition improves vagal reactivity in patients with heart failure.
The deranged autonomic control of heart rate was studied in 34 patients with heart failure (New York Heart Association [NYHA] functional class II to III) by examining the carotid sinus baroreflex.
The carotid sinus baroreceptors were stimulated ... | 13 |
3,207 | Intravenous diclofenac sodium. Does its administration before operation suppress postoperative pain?
Intravenous diclofenac sodium was evaluated in a double-blind randomised trial relative to intramuscular diclofenac, intravenous fentanyl, and intramuscular placebo in 160 patients undergoing extraction of impacted low... | 22 |
2,897 | A new orthosis for central cord syndrome and brachial plexus injuries.
Proximal upper extremity weakness may develop secondary to central cord syndrome due to spinal cord injury or brachial plexus injury.
Functional deficits, pain, decreased upper extremity arm swing during gait, and shoulder subluxation are common s... | 20 |
1,586 | Synchronous reconstruction for combined aortoiliac and femoropopliteal occlusive lesions. The role of proximal bypass.
Between January 1984 and December 1986, 31 patients underwent synchronous revascularization (SR) because of the serious clinical condition of a lower limb and presence of arteriographically visible le... | 13 |
570 | Selective nonoperative management of patients referred with abnormal mammograms.
Screening mammography provides a means of detecting clinically occult breast carcinoma, but the question of whether all abnormal mammograms require biopsy remains unanswered.
We retrospectively reviewed records of 214 women referred over... | 3 |
1,654 | Usefulness of verapamil for congestive heart failure associated with abnormal left ventricular diastolic filling and normal left ventricular systolic performance.
Normal left ventricular systolic performance with impaired left ventricular diastolic filling may be present in a substantial number of patients with conges... | 13 |
1,811 | A randomized trial comparing direct current therapy and bipolar diathermy in the outpatient treatment of third-degree hemorrhoids.
Fifty patients with third-degree hemorrhoids were randomized to receive outpatient treatment with either bipolar diathermy or direct current therapy.
Direct current therapy was used to tr... | 13 |
2,118 | Ventricular stroke work loss: validation of a method of quantifying the severity of aortic stenosis and derivation of an orifice formula
Because aortic stenosis results in the loss of left ventricular stroke work (due to resistance to flow through the valve and turbulence in the aorta), the percentage of stroke work ... | 13 |
2,080 | Physiologic peripheral pulmonic stenosis in infancy.
We studied 14 premature infants with the clinical diagnosis of peripheral pulmonic stenosis (PPS) and 15 normal full-term neonates by echocardiographic Doppler examinations.
The PPS group had an average main pulmonary artery (PA) diameter similar to the control gro... | 13 |
2,758 | Inadequate granulopoiesis after major torso trauma: a hematopoietic regulatory paradox.
Late postinjury sepsis is largely the result of defective host defense including failure to maintain an adequate number of functioning phagocytic cells.
In this study we used stem cell culture techniques to measure colony-stimulat... | 20 |
2,852 | The role of buspirone in the management of alcohol withdrawal: a preliminary investigation.
One hundred eighteen patients, 77 men and 23 women ranging in age from 18 to 70 years of age, admitted to an inpatient facility in Central New York were administered buspirone HCl for treatment of the alcohol withdrawal syndrom... | 20 |
1,498 | Objective tocodynamometry identifies labor onset earlier than subjective maternal perception.
The ability of women instructed in self-detection of uterine contractions to identify the abrupt rise in uterine activity known to precede the onset of labor has not been evaluated.
This study was designed to assess the temp... | 12 |
3,210 | Nitrous oxide and epinephrine-induced arrhythmias.
We asked whether the sympathomimetic effect of nitrous oxide (N2O) predisposed patients receiving N2O to arrhythmias in response to epinephrine administration.
We also asked whether aging contributed to the development of arrhythmias, with or without N2O.
One hundre... | 22 |
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