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Technosignature or technomarker is any measurable property or effect that provides scientific evidence of past or present technology. Technosignatures are analogous to biosignatures, which signal the presence of life, whether intelligent or not. Some authors prefer to exclude radio transmissions from the definition, but such restrictive usage is not widespread
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Archaeology, Anthropology, and Interstellar Communication is a 2014 collection of essays edited by Douglas Vakoch and published by NASA. The book is focused on the role that the humanities and social sciences, in particular anthropology and archaeology, play in the search for extraterrestrial intelligence (SETI). The seventeen essays are gathered into four sections, which respectively explore the history of SETI as a field; archaeological comparisons for human-alien communication, such as the difficulties of translating ancient languages; the inferential gap between humans and aliens, and the consequences this would have for communication and trade; and the potential nature of alien intelligences
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The berserker hypothesis, also known as the deadly probes scenario, is the idea that humans have not yet detected intelligent alien life in the universe because it has been systematically destroyed by a series of lethal Von Neumann probes. The hypothesis is named after the Berserker series of novels (1963-2005) written by Fred Saberhagen. The hypothesis has no single known proposer, and instead is thought to have emerged over time in response to the Hart–Tipler conjecture, or the idea that an absence of detectable Von Neumann probes is contrapositive evidence that no intelligent life exists outside of the Sun's Solar System
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A biosignature (sometimes called chemical fossil or molecular fossil) is any substance – such as an element, isotope, or molecule – or phenomenon that provides scientific evidence of past or present life. Measurable attributes of life include its complex physical or chemical structures and its use of free energy and the production of biomass and wastes. A biosignature can provide evidence for living organisms outside the Earth and can be directly or indirectly detected by searching for their unique byproducts
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A Bracewell probe is a hypothetical concept for an autonomous interstellar space probe dispatched for the express purpose of communication with one or more alien civilizations. It was proposed by Ronald N. Bracewell in a 1960 paper, as an alternative to interstellar radio communication between widely separated civilizations
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Breakthrough Listen is a project to search for intelligent extraterrestrial communications in the Universe. With $100 million in funding and thousands of hours of dedicated telescope time on state-of-the-art facilities, it is the most comprehensive search for alien communications to date. The project began in January 2016, and is expected to continue for 10 years
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In astronomy and astrobiology, the circumstellar habitable zone (CHZ), or simply the habitable zone, is the range of orbits around a star within which a planetary surface can support liquid water given sufficient atmospheric pressure. The bounds of the CHZ are based on Earth's position in the Solar System and the amount of radiant energy it receives from the Sun. Due to the importance of liquid water to Earth's biosphere, the nature of the CHZ and the objects within it may be instrumental in determining the scope and distribution of planets capable of supporting Earth-like extraterrestrial life and intelligence
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The Architects' Resistance (TAR) is a group formed in 1968 by architecture students from Columbia University, the Massachusetts Institute of Technology and Yale University. The group was formed as "a communications network, a research group, and an action group .
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Architecture and Vision (AV) is an international multidisciplinary design agency that was formed in 2003 by Arturo Vittori in partnership with Andreas Volger. AV works in architecture, design, and art. The practice is mainly based around technology transfer between disciplines such as aerospace, art, and architecture
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The New York Five was a group of architects based in New York City whose work was featured in the 1972 book Five Architects. The architects, Peter Eisenman, Michael Graves, Charles Gwathmey, John Hejduk, and Richard Meier, are also often referred to as "the Whites. " Other architects and theorists have been associated with the group, including Werner Seligmann, Kenneth Frampton, Colin Rowe, and Gwathmey's partner Robert Siegel
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The Preservation Foundation of Palm Beach is a private, nonprofit membership organization dedicated to the preservation of the historic, architectural, as well as cultural heritage of Palm Beach, Florida. Through advocacy initiatives, educational programs, architectural resources, and cultural events, the foundation’s goal is to encourage the community to learn about and save the historic buildings that make the town of Palm Beach special. History Founded in 1981, the organization is committed to honoring and preserving Palm Beach’s original architectural treasures and public spaces
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The Situationist International (SI) was an international organization of social revolutionaries made up of avant-garde artists, intellectuals, and political theorists. It was prominent in Europe from its formation in 1957 to its dissolution in 1972. The intellectual foundations of the Situationist International were derived primarily from libertarian Marxism and the avant-garde art movements of the early 20th century, particularly Dada and Surrealism
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Team 10 – just as often referred to as Team X or Team Ten – was a group of architects and other invited participants who assembled starting in July 1953 at the 9th Congress of the International Congresses of Modern Architecture (CIAM) and created a schism within CIAM by challenging its doctrinaire approach to urbanism. Membership The group's first formal meeting under the name of Team 10 took place in Bagnols-sur-Cèze in 1960. The last, with only four members present, was in Lisbon in 1981
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The Tucson Historic Preservation Foundation is a private, nonprofit organization dedicated to the preservation of the historic, architectural, as well as cultural heritage of Tucson, Arizona. Through advocacy initiatives, educational programs, architectural resources, and cultural events, the foundation’s goal is to encourage the community to learn about and preserve the historic buildings that make the Tucson and Pima County unique. History Founded in 1985, the organization is committed to honoring and preserving Tucson's unique architectural treasures and public spaces
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Naval architecture, or naval engineering, is an engineering discipline incorporating elements of mechanical, electrical, electronic, software and safety engineering as applied to the engineering design process, shipbuilding, maintenance, and operation of marine vessels and structures. Naval architecture involves basic and applied research, design, development, design evaluation (classification) and calculations during all stages of the life of a marine vehicle. Preliminary design of the vessel, its detailed design, construction, trials, operation and maintenance, launching and dry-docking are the main activities involved
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The Royal Institution of Naval Architects (also known as RINA) is an international organisation representing naval architects. It is an elite international professional institution based in London. Its members are involved worldwide at all levels in the design, construction, repair and operation of ships, boats and marine structures
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Architectural theory is the act of thinking, discussing, and writing about architecture. Architectural theory is taught in all architecture schools and is practiced by the world's leading architects. Some forms that architecture theory takes are the lecture or dialogue, the treatise or book, and the paper project or competition entry
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Ribophorins are dome shaped transmembrane glycoproteins which are located in the membrane of the rough endoplasmic reticulum, but are absent in the membrane of the smooth endoplasmic reticulum. There are two types of ribophorines: ribophorin I and II. These act in the protein complex oligosaccharyltransferase (OST) as two different subunits of the named complex
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Sex hormone-binding globulin (SHBG) or sex steroid-binding globulin (SSBG) is a glycoprotein that binds to androgens and estrogens. When produced by the Sertoli cells in the seminiferous tubules of the testis, it is called androgen-binding protein (ABP). Other steroid hormones such as progesterone, cortisol, and other corticosteroids are bound by transcortin
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A sialoglycoprotein is a combination of sialic acid and glycoprotein, which is, itself, a combination of sugar and protein. These proteins often contain one or more sialyl oligosaccharides that are covalently bound to the rest of the molecule. Glycophorin C is one common sialoglycoprotein
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SNED1 (Sushi, Nidogen, and EGF-like Domains) is an extracellular matrix (ECM) protein expressed at low levels in a wide range of tissues. The gene encoding SNED1 is located in the human chromosome 2 at locus q37. 3
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Synaptophysin, also known as the major synaptic vesicle protein p38, is a protein that in humans is encoded by the SYP gene. Genomics The gene is located on the short arm of X chromosome (Xp11. 23-p11
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Uromodulin (UMOD), also known as Tamm–Horsfall protein (THP), is a Zona pellucida-like domain-containing glycoprotein that in humans is encoded by the UMOD gene. Uromodulin is the most abundant protein excreted in ordinary urine. Gene The human UMOD gene is located on chromosome 16
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Thyroid-stimulating hormone (also known as thyrotropin, thyrotropic hormone, or abbreviated TSH) is a pituitary hormone that stimulates the thyroid gland to produce thyroxine (T4), and then triiodothyronine (T3) which stimulates the metabolism of almost every tissue in the body. It is a glycoprotein hormone produced by thyrotrope cells in the anterior pituitary gland, which regulates the endocrine function of the thyroid. Physiology Hormone levels TSH (with a half-life of about an hour) stimulates the thyroid gland to secrete the hormone thyroxine (T4), which has only a slight effect on metabolism
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Transcortin, also known as corticosteroid-binding globulin (CBG) or serpin A6, is a protein produced in the liver in animals. In humans it is encoded by the SERPINA6 gene. It is an alpha-globulin
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Tumor-associated glycoprotein 72 (TAG-72) is a glycoprotein found on the surface of many cancer cells, including ovary, breast, colon, lung, and pancreatic cancers. It is a mucin-like molecule with a molar mass of over 1000 kDa. TAG-72 is a tumor marker measured with radioimmunoassays like CA 72-4, which uses the monoclonal antibodies indium (111In) satumomab pendetide and iodine (125I) minretumomab
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Variant surface glycoprotein (VSG) is a ~60kDa protein which densely packs the cell surface of protozoan parasites belonging to the genus Trypanosoma. This genus is notable for their cell surface proteins. They were first isolated from Trypanosoma brucei in 1975 by George Cross
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Verrucotoxin (VTX) is a lethal venom produced by the dorsal fins of Synanceia verrucosa. This species of reef stonefish is connected to the family Synanceiidae. The venom of this species of stonefish is a tetrameric glycoprotein with cardiovascular and cytolytic effects
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Vitronectin (VTN or VN) is a glycoprotein of the hemopexin family which is synthesized and excreted by the liver, and abundantly found in serum, the extracellular matrix and bone. In humans it is encoded by the VTN gene. Vitronectin binds to integrin alpha-V beta-3 and thus promotes cell adhesion and spreading
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In chemistry, a glycoside is a molecule in which a sugar is bound to another functional group via a glycosidic bond. Glycosides play numerous important roles in living organisms. Many plants store chemicals in the form of inactive glycosides
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Alkyl polyglycosides (APGs) are a class of non-ionic surfactants widely used in a variety of cosmetic, household, and industrial applications. Biodegradable and plant-derived from sugars, these surfactants are usually glucose derivatives, and fatty alcohols. The raw materials are typically starch and fat, and the final products are typically complex mixtures of compounds with different sugars comprising the hydrophilic end and alkyl groups of variable length comprising the hydrophobic end
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Maltitol is a sugar alcohol (a polyol) used as a sugar substitute. It has 75–90% of the sweetness of sucrose (table sugar) and nearly identical properties, except for browning. It is used to replace table sugar because it is half as energetic, does not promote tooth decay, and has a somewhat lesser effect on blood glucose
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Prymnesin-2 is an organic compound that is secreted by the haptophyte Prymnesium parvum. It belongs to the prymnesin family and has potent hemolytic and ichthyotoxic properties. In a purified form it appears as a pale yellow solid
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Prymnesin-B1 is a chemical with the molecular formula C91H132ClNO34. It is a member of the prymnesins, a class of ladder-frame polyether phycotoxins made by the alga Prymnesium parvum. It is known to be toxic to fish
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Ptaquiloside is a norsesquiterpene glucoside produced by bracken ferns (majorly Pteridium aquilinum) during metabolism. It is identified to be the main carcinogen of the ferns and to be responsible for their biological effects, such as haemorrhagic disease and bright blindness in livestock and oesophageal, gastric cancer in humans. Ptaquiloside has unstable chemical structure and acts as a DNA alkylating agent under physiological conditions
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Yariv reagent (1,3,5-tri(p-glycosyloxyphenylazo)-2,4,6-trihydroxybenzene) is a glycosylated phenolic compound that binds strongly to galactans and arabinogalactan proteins. It can therefore be used in their detection, quantification, precipitation, isolation, staining, and interfere with their function. It was initially synthesised in 1962 as an antigen for carbohydrate-binding antibodies but has subsequently become more broadly used
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Neuraminidase inhibitors (NAIs) are a class of drugs which block the neuraminidase enzyme. They are a commonly used antiviral drug type against influenza. Viral neuraminidases are essential for influenza reproduction, facilitating viral budding from the host cell
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Neuraminidase inhibitors inhibit enzymatic activity of the enzyme neuraminidase (sialidase). These type of inhibitors have been introduced as anti-influenza drugs as they prevent the virus from exiting infected cells and thus stop further spreading of the virus. Neuraminidase inhibitors for human neuraminidase (hNEU) have the potential to be useful drugs as the enzyme plays a role in several signaling pathways in cells and is implicated in diseases such as diabetes and cancer
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Laninamivir (CS-8958) is a neuraminidase inhibitor that is a drug used for the treatment and prophylaxis of Influenzavirus A and Influenzavirus B. It is currently in Phase III clinical trials. It is a long-acting neuraminidase inhibitor administered by nasal inhalation
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Oseltamivir, sold under the brand name Tamiflu, is an antiviral medication used to treat and prevent influenza A and influenza B, viruses that cause the flu. Many medical organizations recommend it in people who have complications or are at high risk of complications within 48 hours of first symptoms of infection. They recommend it to prevent infection in those at high risk, but not the general population
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Peramivir (trade name Rapivab) is an antiviral drug developed by BioCryst Pharmaceuticals for the treatment of influenza. Peramivir is a neuraminidase inhibitor, acting as a transition-state analogue inhibitor of influenza neuraminidase and thereby preventing new viruses from emerging from infected cells. It is approved for intravenous administration
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Analytical Biochemistry is a peer-reviewed scientific journal established in 1960. It covers the field of biochemistry. According to the Journal Citation Reports, the journal has a 2014 impact factor of 2
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Annual Review of Biochemistry is an annual peer-reviewed scientific journal published by Annual Reviews, a nonprofit scientific publisher. Its first volume was published in 1932, and its founding editor was J. Murray Luck
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Annual Review of Chemical and Biomolecular Engineering is an annual peer-reviewed scientific journal published by Annual Reviews, covering chemical and biomolecular engineering. The co-editors are Michael F. Doherty and Rachel A
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Antioxidants is a peer-reviewed open-access scientific journal that covers various areas of antioxidants research, including biosynthesis, pharmacodynamics, and synthetic antioxidants. It is published by MDPI and was established in 2012. The editor-in-chief is Stanley Omaye (University of Nevada)
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Archives of Biochemistry and Biophysics is a biweekly peer-reviewed scientific journal that covers research on all aspects of biochemistry and biophysics. It is published by Elsevier and as of 2012, the editors-in-chief are Paul Fitzpatrick (University of Texas Health Science Center at San Antonio), Helmut Sies (University of Düsseldorf), Jian-Ping Jin (Wayne State University School of Medicine), and Henry Jay Forman (University of Southern California). History The journal was established in 1942 by Academic Press as the Archives of Biochemistry, obtaining its current name in 1952
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Bioanalysis is a biweekly peer-reviewed scientific journal established in 2009 and published by Future Science. The editor-in-chief is Neil Spooner (Spooner Bioanalytical Solutions Ltd, UK). The journal covers the field of bioanalysis, including drug and metabolite assays, chromatography and separation sciences, ligand binding assays, metabolomics, and key detection methods
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Biocatalysis & Biotransformation is an academic journal that provides coverage of the application, both actual and potential of biological catalysts, including whole cells or isolated components thereof, natural and modified enzymes and catalytic antibodies for the synthesis, interconversion or degradation of chemical species. It is published by Informa Healthcare. Core areas Coverage includes: Mechanistic, principles, kinetics and thermodynamics of biocatalytic processes The chemical or genetic modification of biocatalysts Metabolic engineering Activity and stability of biocatalysts in non-aqueous and multi-phasic environments Environmental applications of biocatalysis Editor-in-chief David Leak is the editor-in-chief of Biocatalysis & Biotransformation
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Biochemia Medica is a triannual peer-reviewed scientific journal covering biochemistry, clinical chemistry, and laboratory medicine. It was established in 1991 and is published by the Croatian Society of Medical Biochemistry and Laboratory Medicine. In 2006, the existing editor-in-chief and editorial board were replaced, and the new editorial board redesigned the journal's entire format; soon afterward, the journal was indexed in both EMBASE and Scopus
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Biochemical and Biophysical Research Communications is a weekly peer-reviewed scientific journal covering all aspects of biochemistry and biophysics. It was established in 1959 by Academic Press and is currently published by Elsevier. The editor-in-chief is Wolfgang Baumeister (Max Planck Institute of Biochemistry)
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The Biochemical Journal is a peer-reviewed scientific journal which covers all aspects of biochemistry, as well as cell and molecular biology. It is published by Portland Press and was established in 1906. History The journal was established in 1906 by Benjamin Moore, holder of the first UK chair of biochemistry at the University of Liverpool, with financial support from Edward Whitley, an heir of the Greenall Whitley brewers
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Biochemical Pharmacology is a peer-reviewed medical journal published by Elsevier. It covers research on the pharmacodynamics and pharmacokinetics of drugs and non-therapeutic xenobiotics. The editor-in-chief is S
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Biochemical Society Transactions is a bimonthly peer-reviewed scientific journal which publishes the transactions of the annual conference and focused meetings of the Biochemical Society, together with independent meetings supported by the society. The society's annual symposium, previously published only in Biochemical Society Symposium, was first published in the Transactions in 2008. The journal was established in 1973 and is published by Portland Press, the Society's publishing arm
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Biological Chemistry is a peer-reviewed scientific journal focusing on biological chemistry. The journal is published by Walter de Gruyter and the current editor-in-chief is Bernhard Brüne. History The journal was established by Felix Hoppe-Seyler in 1877, under the name Zeitschrift für Physiologische Chemie (English: Journal of Physiological Chemistry), and was edited by him until his death in 1895
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Biological Trace Element Research is a journal established in 1979 and published by Springer Science+Business Media. The editor-in-chief is M. F
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Biomarker Insights is a peer-reviewed open access academic journal focusing on biomarkers and their clinical applications. The journal aims to be a venue for rapid communications in the field. The journal was established in 2006 and was originally published by Libertas Academica
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Biomarkers in Medicine is a monthly peer-reviewed medical journal established in 2007 and published by Future Medicine. The editors-in-chief are Andre Terzic (Mayo Clinic and Scott Waldman (Thomas Jefferson University). The journal covers all aspects of research on biomarkers
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BioMetals is a bimonthly peer-reviewed scientific journal covering the role of metal ions in biological systems. It is published by Springer Science+Business Media and the editor-in-chief are Isabelle Michaud-Soret and Christopher Rensing. Associate editors are Hans Vogel, Hajo Haase and Shelley Payne
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Biopolymers is a biweekly peer-reviewed scientific journal covering the study of biopolymers from a biochemical and biophysical perspective. It was established in 1963 and is published by John Wiley & Sons. The editor-in-chief is Hilary J
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Biotechnology and Applied Biochemistry is a bimonthly peer-reviewed scientific journal covering biotechnology applied to medicine, veterinary medicine, and diagnostics. Topics covered include the expression, extraction, purification, formulation, stability, and characterization of both natural and recombinant biological molecules. It is published by Wiley-Blackwell on behalf of the International Union of Biochemistry and Molecular Biology
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Calcified Tissue International is a peer-reviewed medical journal published by Springer Science+Business Media and first launched in 1967. From 1967 to 1978, the journal was published under the name Calcified Tissue Research. It is an official journal of the International Osteoporosis Foundation
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Carbohydrate Research is a peer-reviewed scientific journal covering research on the chemistry of carbohydrates. It is published by Elsevier and was established in 1965. The editor-in-chief is M
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Cell Biochemistry & Function is a peer-reviewed scientific journal published by Wiley-Blackwell. Its 2010 impact factor is 1. 651
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ChemBioChem is a peer-reviewed scientific journal covering chemical biology, synthetic biology, and bio-nanotechnology and published by Wiley-VCH on behalf of Chemistry Europe. The journal publishes communications, full papers, reviews, minireviews, highlights, concepts, book reviews, and conference reports. Viewpoints, correspondence, essays, web sites, and databases are also occasionally featured
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Critical Reviews in Biochemistry and Molecular Biology is a bimonthly scientific journal that publishes comprehensive review articles in the areas of biochemistry and molecular biology. It was established in 1972 under the name Critical Reviews in Biochemistry, obtaining its current name in 1989. It is published by Taylor and Francis Group and the editor-in-chief is Bridget Sheppard
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Cytokine is a monthly peer-reviewed academic journal covering the study of cytokines as they relate to multiple disciplines, including molecular biology, immunology, and genetics. It was established in 1989 and is published by Elsevier. It is the official journal of the International Cytokine & Interferon Society
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The FEBS Journal is a biweekly peer-reviewed scientific journal published by John Wiley & Sons on behalf of the Federation of European Biochemical Societies. It covers research on all aspects of biochemistry, molecular biology, cell biology, and the molecular bases of disease. The editor-in-chief is Seamus Martin (Trinity College Dublin), who took over from Richard Perham (University of Cambridge) in 2014
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FEBS Letters is a not-for-profit peer-reviewed scientific journal published on behalf of the Federation of European Biochemical Societies (FEBS) by Wiley. It covers all aspects of molecular biosciences, including molecular biology and biochemistry. The aim of the journal is to publish primary research in the form of Research Articles, Research Letters, Communications and Hypotheses, as well as secondary research in the form of Review articles
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Glycobiology is a monthly peer-reviewed scientific journal covering all aspects of the field of glycobiology and the official journal of the Society for Glycobiology. It is published by Oxford University Press. The journal was established in September 1990
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The International Journal of Biological Macromolecules is a peer-reviewed scientific journal covering research into chemical and biological aspects of all natural macromolecules. It publishes articles on the molecular structure of proteins, macromolecular carbohydrates, lignins, biological poly-acids, and nucleic acids. It also includes biological activities and interactions, molecular associations, chemical and biological modifications, and functional properties as well as development of related model systems, structural including conformational studies, new analytical techniques, and relevant theoretical developments
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The International Journal of Molecular Sciences is a peer-reviewed open access scientific journal covering research in chemistry, molecular physics, and molecular biology. It is published by MDPI and was established in 2000. The editor-in-chief is Maurizio Battino (Marche Polytechnic University)
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Journal of Biological Inorganic Chemistry is a peer-reviewed scientific journal. It is an official publication of the Society of Biological Inorganic Chemistry and published by Springer Science+Business Media. Subjects covered Areas of research covered in the journal include: advances in the understanding of systems involving one or more metal ions set in a biological matrix - particularly metalloproteins and metal-nucleic acid complexes - in order to understand biological function at the molecular level
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The Journal of Biomolecular NMR publishes research on technical developments and innovative applications of nuclear magnetic resonance spectroscopy for the study of structure and dynamic properties of biopolymers in solution, liquid crystals, solids and mixed environments. Some of the main topics include experimental and computational approaches for the determination of three-dimensional structures of proteins and nucleic acids, advancements in the automated analysis of NMR spectra, and new methods to probe and interpret molecular motions. The journal was founded in 1991 by Kurt Wüthrich, who later received a Nobel prize in Chemistry in 2002 for his seminal contributions to the field of NMR
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The Journal of Clinical Lipidology is a bimonthly peer-reviewed medical journal covering medical aspects of lipidology. It was established in 2007 and is the official journal of the National Lipid Association. It is published by Elsevier and the editor-in-chief is John Richard Guyton (Duke University Medical Center)
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The Journal of Inorganic Biochemistry is a monthly peer-reviewed scientific journal covering research on the inorganic aspects of biochemistry, such as metalloenzymes and metallobiomolecules. The journal was established in 1971 as Bioinorganic Chemistry, obtaining its current name in 1979. Since 1996, the editor-in-chief has been John H
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The Journal of Molecular Biology is a biweekly peer-reviewed scientific journal covering all aspects of molecular biology. It was established in 1959 and is published by Elsevier. The editor-in-chief is Peter Wright (The Scripps Research Institute)
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The Journal of Molecular Recognition is a monthly peer-reviewed scientific journal publishing original research papers and reviews describing molecular recognition phenomena in biology. The current editor-in-chief is Marc H. V
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The Journal of Steroid Biochemistry and Molecular Biology is a peer-reviewed scientific journal, covering all aspects of steroid metabolism. It was established in the 1969 as Journal of Steroid Biochemistry and obtained its current name in 1990. The editor-in-chief is Jerzy Adamski (Helmholtz Zentrum München)
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Sargon III is a computer chess software. It is a sequel to Sargon II. Gameplay Sargon III allots a time budget based on which level of play is chosen
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The Secret of Monkey Island is a 1990 point-and-click graphic adventure game developed and published by Lucasfilm Games. It takes place in a fictional version of the Caribbean during the age of piracy. The player assumes the role of Guybrush Threepwood, a young man who dreams of becoming a pirate, and explores fictional islands while solving puzzles
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Sex Olympics, alternatively titled Brad Stallion in Sex Olympics is an erotic point-and-click adventure game developed and self-published by Free Spirit Software, and released for DOS, Atari ST, and Amiga. The Amiga version of Sex Olympics was released in Europe in April 1991. Sex Olympics is the finale of the Brad Stallion series, and is preceded by Sex Vixens from Space (1988), Planet of Lust (1989), and Bride of the Robot (1989)
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Shadow of the Beast II is a platform game developed by Reflections and published by Psygnosis in 1990. It is the sequel to the earlier Shadow of the Beast. Plot and gameplay Shadow of the Beast II finds the hero Aarbron in half-beast form, wandering the lands of Karamoon in search of his kidnapped sister
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Shoot-'Em-Up Construction Kit (a. k. a
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Sidewize is a horizontally scrolling shooter released by Firebird in 1987 for the Commodore 64 and ZX Spectrum home computers. It was followed by a sequel, Crosswize. Plot The four worlds of Omicron, Nu, Delta and Iota are under siege by the Dariard Mutants
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Silent Service II is a submarine simulation game developed and published by MicroProse for MS-DOS in 1990 and for the Amiga in 1991. It is a sequel to 1985's Silent Service, also set in the Pacific Ocean during World War II. Tommo purchased the rights to this game and digitally publishes it through its Retroism brand in 2015
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Silicon Dreams is a trilogy of interactive fiction games developed by Level 9 Computing during the 1980s. The first game was Snowball, released during 1983, followed a year later by Return to Eden, and then by The Worm in Paradise during 1985. The next year they were vended together as the first, second and last of the Silicon Dreams
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Sinbad and the Throne of the Falcon is a 1987 action-adventure game developed and published by Cinemaware. Set in an Arabian Nights-esque world, the player assumes the role of Sinbad the Sailor, and is commissioned by The Princess to rid the land of the Dark Prince. The game was designed and programmed by Bill Williams for the Amiga, who also wrote Mind Walker
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SkyChase is a combat flight simulator designed by Ralph Russell in 1988. It is the first game developed by Maxis. Gameplay SkyChase is an arcadey combat flight simulator often compared to Top Gun by Ocean Software
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Slightly Magic is an action-adventure game published in 1991 by Codemasters for the Amiga, Amstrad CPC, Atari ST, Commodore 64 and ZX Spectrum. It was written by Colin Jones, author of Rock Star Ate My Hamster (also by Codemasters). Plot Bigwiz the wizard has left the castle in a hurry and has been a bit forgetful
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Endothermic organisms known as homeotherms maintain internal temperatures with minimal metabolic regulation within a range of ambient temperatures called the thermal neutral zone (TNZ). Within the TNZ the basal rate of heat production is equal to the rate of heat loss to the environment. Homeothermic organisms adjust to the temperatures within the TNZ through different responses requiring little energy
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Thermoregulation is the ability of an organism to keep its body temperature within certain boundaries, even when the surrounding temperature is very different. A thermoconforming organism, by contrast, simply adopts the surrounding temperature as its own body temperature, thus avoiding the need for internal thermoregulation. The internal thermoregulation process is one aspect of homeostasis: a state of dynamic stability in an organism's internal conditions, maintained far from thermal equilibrium with its environment (the study of such processes in zoology has been called physiological ecology)
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Tissue hydration is the process of absorbing and retaining water in biological tissues. Plants Land plants maintain adequate tissue hydration by means of an outer waterproof layer. In soft or green tissues, this is usually a waxy cuticle over the outer epidermis
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Toxungen comprises a secretion or other body fluid of one or more biological toxins that is transferred by one animal to the external surface of another animal via a physical delivery mechanism. Toxungens can be delivered through spitting, spraying, or smearing. As one of three categories of biological toxins, toxungens can be distinguished from poisons, which are passively transferred via ingestion, inhalation, or absorption across the skin, and venoms, which are delivered through a wound generated by a bite, sting, or other such action
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Venom or zootoxin is a type of toxin produced by an animal that is actively delivered through a wound by means of a bite, sting, or similar action. The toxin is delivered through a specially evolved venom apparatus, such as fangs or a stinger, in a process called envenomation. Venom is often distinguished from poison, which is a toxin that is passively delivered by being ingested, inhaled, or absorbed through the skin, and toxungen, which is actively transferred to the external surface of another animal via a physical delivery mechanism
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Voluntary action is an anticipated goal-oriented movement. The concept of voluntary action arises in many areas of study, including cognitive psychology, operant conditioning, philosophy, neurology, criminology, and others. Additionally, voluntary action has various meanings depending on the context in which it is used
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Warm-blooded is hot and warm is an informal term referring to animal species whose bodies maintain a temperature higher than that of their environment. In particular, homeothermic species (including birds and mammals) maintain a stable body temperature by regulating metabolic processes. Other species have various degrees of thermoregulation
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Wildlife endocrinology is a branch of endocrinology which deals with the study of the endocrine system in vertebrates as well as invertebrates. It deals with hormone analysis which helps understand the basic physiological functions such as metabolic activity, reproduction, health and well-being of the organism. Hormones can be measured via multiple biological matrices such as blood, urine, faeces, hair and saliva, the choice of which depends upon the type of information required, ease of sample collection, assays available to analyse the sample and species difference in hormone metabolism and excretion
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Bioadhesives are natural polymeric materials that act as adhesives. The term is sometimes used more loosely to describe a glue formed synthetically from biological monomers such as sugars, or to mean a synthetic material designed to adhere to biological tissue. Bioadhesives may consist of a variety of substances, but proteins and carbohydrates feature prominently
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C5orf24 (chromosome 5 open reading frame 24) is a protein encoded by the C5orf24 gene (5q31. 1) in humans. C5orf24 is primarily localized to the nucleus and is highly conserved with orthologs in mammals, birds, reptiles, amphibians, and fish
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A helminth protein, or helminthic antigen, is a protein derived from a parasitic worm that causes an immune reaction. When secreted, these proteins may modify the host's immune response in order to promote longevity of the parasite. Helminth proteins can result in a deregulated response to infection, and are implicated in reduced reactivity to other antigens
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