id stringlengths 8 8 | name stringlengths 5 37 | translator_id stringlengths 9 29 | drugbank_id stringlengths 7 12 ⌀ | synonyms listlengths 0 7 | aggregated_with listlengths 0 13 | drug_class stringlengths 4 79 ⌀ | therapeutic_area stringclasses 98
values | drug_function stringlengths 5 201 ⌀ | drug_target stringlengths 2 221 ⌀ | approved_usa stringclasses 3
values | is_antipsychotic bool 2
classes | is_sedative bool 2
classes | is_antimicrobial bool 2
classes | is_glucose_regulator bool 2
classes | is_chemotherapy bool 2
classes | is_steroid bool 2
classes | is_analgesic bool 2
classes | is_cardiovascular bool 2
classes | is_cell_therapy bool 2
classes | atc_main stringlengths 7 7 ⌀ | atc_level_1 stringclasses 14
values | atc_level_2 stringclasses 80
values | atc_level_3 stringclasses 169
values | atc_level_4 stringlengths 5 5 ⌀ | atc_level_5 stringlengths 7 7 ⌀ | l1_label stringclasses 14
values | l2_label stringclasses 80
values | l3_label stringclasses 169
values | l4_label stringlengths 6 102 ⌀ | l5_label stringlengths 6 28 ⌀ | deleted bool 2
classes | deleted_reason stringclasses 8
values | new_id stringclasses 4
values | is_fda_generic_drug bool 2
classes | __index_level_0__ int64 0 1.82k |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
EC:00101 | Apremilast | CHEBI:78540 | DB05676 | [] | [] | PDE-4 inhibitor | Immune | Antiinflammatory | PDE-4 inhibitor | APPROVED | false | false | false | false | false | false | false | false | false | L04AA32 | L | L04 | L04A | L04AA | L04AA32 | Antineoplastic and immunomodulating agents | Immunosuppressants | Immunosuppressants | Selective immunosuppressants | Apremilast | false | null | null | true | 100 |
EC:00102 | Aprepitant | CHEBI:499361 | DB00673 | [] | [
"Fosaprepitant"
] | Neurokinin 1 (NK1) receptor antagonists | Gastrointestinal; Central nervous system | Antiemetic | Substance P/Neurokinin 1 Receptor Antagonist | APPROVED | false | false | false | false | false | false | false | false | false | A04AD12 | A | A04 | A04A | A04AD | A04AD12 | Alimentary tract and metabolism drugs | Antiemetics and antinauseants | Antiemetics and antinauseants | Other antiemetics in atc | Aprepitant | false | null | null | true | 101 |
EC:00103 | Aprocitentan | CHEBI:76609 | DB15059 | [] | [] | Endothelin receptor antagonist | Cardiovascular | Vasodilator | Endothelin receptor antagonist | APPROVED | false | false | false | false | false | false | false | true | false | C02KN01 | C | C02 | C02K | C02KN | C02KN01 | Cardiovascular system drugs | Antihypertensives | Other antihypertensives in atc | Other antihypertensives in atc | Aprocitentan | false | null | null | false | 102 |
EC:00104 | Arformoterol | CHEBI:408174 | DB01274 | [] | [] | Long acting beta-2 agonist | Respiratory | Bronchodilator | Beta-2 agonist | APPROVED | false | false | false | false | false | false | false | false | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | true | 103 |
EC:00105 | Argatroban | CHEBI:94385 | DB00278 | [
"Argatroban monohydrate"
] | [] | Direct thrombin inhibitor | Hematology | Anticoagulant | Direct thrombin inhibitor | APPROVED | false | false | false | false | false | false | false | false | false | B01AE03 | B | B01 | B01A | B01AE | B01AE03 | Blood and blood forming organ drugs | Antithrombotic agents | Antithrombotic agents | Direct thrombin inhibitors | Argatroban | false | null | null | true | 104 |
EC:00106 | Arginine | CHEBI:16467 | DB00125 | [
"L-arginine",
"Arginine hydrochloride"
] | [] | Arginine | Metabolic | Amino acid replacement | Arginine replacement | APPROVED | false | false | false | false | false | false | false | false | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | false | 105 |
EC:00107 | Arimoclomol | UNII:EUT3557RT5 | DB05025 | [] | [] | HSP70 inducer | Metabolic | Clears protein aggregates | Heat shock protein inducer | APPROVED | false | false | false | false | false | false | false | false | false | N07XX17 | N | N07 | N07X | N07XX | N07XX17 | Nervous system drugs | Other nervous system drugs in atc | Other nervous system drugs in atc | Other nervous system drugs in atc | Arimoclomol | false | null | null | false | 106 |
EC:00108 | Aripiprazole | CHEBI:31236 | DB01238 | [] | [] | Atypical antipsychotic | Central nervous system | Antipsychotic | D2 partial agonist | 5-HT1A partial agonist | 5-HT2A antagonist | APPROVED | true | false | false | false | false | false | false | false | false | N05AX12 | N | N05 | N05A | N05AX | N05AX12 | Nervous system drugs | Psycholeptics | Antipsychotics | Other antipsychotics in atc | Aripiprazole | false | null | null | true | 107 |
EC:00109 | Armodafinil | CHEBI:77590 | DB06413 | [] | [] | CNS stimulant | Central nervous system | CNS stimulant | Increase extracellular dopamine | APPROVED | false | false | false | false | false | false | false | false | false | N06BA13 | N | N06 | N06B | N06BA | N06BA13 | Nervous system drugs | Psychoanaleptics | Psychostimulants, agents used for adhd and nootropics | Centrally acting sympathomimetics | Armodafinil | false | null | null | true | 108 |
EC:00110 | Arsenic trioxide | PUBCHEM.COMPOUND:261004 | DB01169 | [] | [] | Miscellaneous antineoplastic agent | Targeted cancer therapy | Miscellaneous antineoplastic agent | Miscellaneous | APPROVED | false | false | false | false | false | false | false | false | false | L01XX27 | L | L01 | L01X | L01XX | L01XX27 | Antineoplastic and immunomodulating agents | Antineoplastic agents | Other antineoplastic agents in atc | Other antineoplastic agents in atc | Arsenic trioxide | false | null | null | true | 109 |
EC:00111 | Artemether | CHEBI:195280 | DB06697 | [] | [] | Artemisinin | Antimicrobial | Antiparasitic | Antimalarial | APPROVED | false | false | true | false | false | false | false | false | false | P01BE02 | P | P01 | P01B | P01BE | P01BE02 | Antiparasitic products, insecticides and repellents | Antiprotozoals | Antimalarials | Artemisinin and derivatives, plain | Artemether | false | null | null | false | 110 |
EC:00112 | Artesunate | CHEBI:63918 | DB09274 | [] | [] | Artemisinin | Antimicrobial | Antiparasitic | Antimalarial | APPROVED | false | false | true | false | false | false | false | false | false | P01BE03 | P | P01 | P01B | P01BE | P01BE03 | Antiparasitic products, insecticides and repellents | Antiprotozoals | Antimalarials | Artemisinin and derivatives, plain | Artesunate | false | null | null | false | 111 |
EC:00113 | Articaine | CHEBI:91834 | DB09009 | [] | [] | Amide local anesthetic | Peripheral nervous system | Local anesthetic | Voltage-gated sodium channel blocker | APPROVED | false | false | false | false | false | false | false | false | false | N01BB08 | N | N01 | N01B | N01BB | N01BB08 | Nervous system drugs | Anesthetics | Local anesthetics | Amide local anesthetics | Articaine | false | null | null | false | 112 |
EC:00114 | Asciminib | UNII:L1F3R18W77 | DB12597 | [] | [] | BCR-ABL inhibitor | Targeted cancer therapy | Small molecule inhibitor | BCR-ABL1 kinase inhibitor | APPROVED | false | false | false | false | false | false | false | false | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | false | 113 |
EC:00115 | Ascorbic acid | CHEBI:22652 | DB00126 | [
"Vitamin c"
] | [] | Vitamin C | Supplement | Vitamin | Vitamin C | APPROVED | false | false | false | false | false | false | false | false | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | true | 114 |
EC:00116 | Asenapine | CHEBI:71253 | DB06216 | [] | [] | Atypical antipsychotic | Central nervous system | Antipsychotic (atypical) | Dopamine antagonist | APPROVED | true | false | false | false | false | false | false | false | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | true | 115 |
EC:00117 | Asfotase alfa | UNII:Z633861EIM | DB09105 | [
"Human recombinant alkaline phosphatase"
] | [] | Alkaline phosphatase replacement | Musculoskeletal | Bone mineralisation | human recombinant tissue-nonspecific alkaline phosphatase | APPROVED | false | false | false | false | false | false | false | false | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | false | 116 |
EC:00118 | Asparaginase | UMLS:C0003993 | null | [
"Asparaginase",
"Recombinant erwinia asparaginase",
"Asparaginase escherichia coli"
] | [] | Asparaginase inhibitor | Targeted cancer therapy | Miscellaneous antineoplastic agent | Asparagine catabolism to reduce exogenous asparagine for leukemia cells | APPROVED | false | false | false | false | false | false | false | false | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | false | 117 |
EC:00119 | Aspirin | CHEBI:15365 | DB00945 | [
"Acetylsalicylic acid"
] | [] | NSAID | Hematology; Cardiovascular | Antiplatelet | COX-1 inhibitor | APPROVED | false | false | false | false | false | false | true | true | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | true | 118 |
EC:00120 | Ataluren | CHEBI:94805 | DB05016 | [] | [] | DMD nonsense mutation readthrough agent | Musculoskeletal | Restores the production of key proteins like dystrophin | Promotes ribosomal readthrough of premature stop codons (nonsense mutations) in mRNA | NOT_APPROVED | false | false | false | false | false | false | false | false | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | false | 119 |
EC:00121 | Atazanavir | CHEBI:37924 | DB01072 | [] | [] | HIV Protease Inhibitor | Antimicrobial | Antiviral | HIV | APPROVED | false | false | true | false | false | false | false | false | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | true | 120 |
EC:00122 | Atenolol | CHEBI:2904 | DB00335 | [] | [] | Beta blocker | Cardiovascular | Antihypertensive | Beta-1 antagonist | APPROVED | false | false | false | false | false | false | false | true | false | C07AB03 | C | C07 | C07A | C07AB | C07AB03 | Cardiovascular system drugs | Beta-adrenergic blocking agents | Beta blocking agents | Beta blocking agents, selective | Atenolol | false | null | null | true | 121 |
EC:00123 | Atezolizumab | UNII:52CMI0WC3Y | DB11595 | [] | [] | Anti-PD-L1 | Targeted cancer therapy | Immune checkpoint inhibitor | Anti-PD-L1 | APPROVED | false | false | false | false | false | false | false | false | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | false | 122 |
EC:00124 | Atidarsagene autotemcel | DRUGBANK:DB17538 | DB17538 | [] | [] | Gene therapy | Gene therapy | Gene therapy (ex vivo) | Modified cells to produce functional arylsulfatase A enzyme | APPROVED | false | false | false | false | false | false | false | false | true | A16AB21 | A | A16 | A16A | A16AB | A16AB21 | Alimentary tract and metabolism drugs | Other alimentary tract and metabolism products in atc | Other alimentary tract and metabolism products in atc | Enzymes for alimentary tract and metabolism | Atidarsagene autotemcel | false | null | null | false | 123 |
EC:00125 | Atogepant | CHEBI:196955 | DB16098 | [] | [] | CGRP Receptor Antagonist | Central nervous system | Antimigraine | CGRP receptor antagonist | APPROVED | false | false | false | false | false | false | false | false | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | false | 124 |
EC:00126 | Atomoxetine | CHEBI:127342 | DB00289 | [] | [] | Norepinephrine reuptake inhibitor (NRI) | Central nervous system | Anti-ADHD | Selective NE reuptake inhibitor (NRI) | APPROVED | false | false | false | false | false | false | false | false | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | true | 125 |
EC:00127 | Atorvastatin | CHEBI:39548 | DB01076 | [] | [] | Statin | Cardiovascular | Lipid-lowering | HMG-CoA Reductase Inhibitor | APPROVED | false | false | false | false | false | false | false | true | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | true | 126 |
EC:00128 | Atosiban | CHEBI:135899 | DB09059 | [] | [] | Oxytocin receptor antagonist | Obstetrics | Tocolytic | Oxytocin receptor antagonist | NOT_APPROVED | false | false | false | false | false | false | false | false | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | false | 127 |
EC:00129 | Atovaquone | CHEBI:575568 | DB01117 | [] | [] | Cytochrome bc1 inhibitor | Antimicrobial | Antiparasitic | Cytochrome bc1 inhibitor | APPROVED | false | false | true | false | false | false | false | false | false | P01AX06 | P | P01 | P01A | P01AX | P01AX06 | Antiparasitic products, insecticides and repellents | Antiprotozoals | Agents against amoebiasis and other protozoal diseases | Other agents against amoebiasis and other protozoal diseases in atc | Atovaquone | false | null | null | true | 128 |
EC:00130 | Atracurium | CHEBI:2914 | DB13295 | [
"Atracurium besilate"
] | [] | nAChR antagonist (muscular) | Peripheral nervous system | Neuromuscular blocker | Muscular nicotinic ACh inhibitor (at NMJ) | APPROVED | false | false | false | false | false | false | false | false | false | M03AC04 | M | M03 | M03A | M03AC | M03AC04 | Musculo-skeletal system drugs | Muscle relaxants | Muscle relaxants, peripherally acting agents | Other quaternary ammonium compounds in atc, muscle relaxants, peripherally acting | Atracurium | false | null | null | true | 129 |
EC:00131 | Atrasentan | CHEBI:135810 | DB06199 | [] | [] | Endothelin receptor antagonist | Renal | Vasodilator | Endothelin receptor antagonist | APPROVED | false | false | false | false | false | false | false | false | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | false | 130 |
EC:00132 | Atropine | CHEBI:92712 | DB00572 | [
"Atropine sulfate"
] | [] | Antimuscarinic | Cardiovascular; Peripheral nervous system; Ophthalmic | Parasympathetic inhibitor | Anticholingeric (non-selective muscarinic) | APPROVED | false | false | false | false | false | false | false | true | false | A03BA01 | A | A03 | A03B | A03BA | A03BA01 | Alimentary tract and metabolism drugs | Drugs for functional gastrointestinal disorders | Belladonna and derivatives containing drugs, plain for functional gastrointestinal disorders | Belladonna alkaloids, tertiary amines for functional gastrointestinal disorders | Atropine | false | null | null | true | 131 |
EC:00133 | Auranofin | CHEBI:2922 | DB00995 | [] | [] | Gold compound DMARD | Immune | Immunosuppressant | Gold compound | APPROVED | false | false | false | false | false | false | false | false | false | M01CB03 | M | M01 | M01C | M01CB | M01CB03 | Musculo-skeletal system drugs | Antiinflammatory and antirheumatic products | Specific antirheumatic agents | Gold preparations | Auranofin | false | null | null | false | 132 |
EC:00134 | Avacincaptad pegol | UNII:TT0V5JLG5B | DB15165 | [] | [] | Complement inhibitor | Ophthalmic | Complement inhibitor | C5 inhibitor | APPROVED | false | false | false | false | false | false | false | false | false | S01XA32 | S | S01 | S01X | S01XA | S01XA32 | Sensory organ drugs | Ophthalmologicals | Other ophthalmologicals in atc | Other ophthalmologicals in atc | null | false | null | null | false | 133 |
EC:00135 | Avacopan | UNII:O880NM097T | DB15011 | [] | [] | Complement inhibitor | Immune | Complement inhibitor | C5a receptor inhibitor | APPROVED | false | false | false | false | false | false | false | false | false | L04AJ05 | L | L04 | L04A | L04AJ | L04AJ05 | Antineoplastic and immunomodulating agents | Immunosuppressants | Immunosuppressants | Complement inhibitors | Avacopan | false | null | null | false | 134 |
EC:00136 | Avalglucosidase alfa | UNII:EO144CP0X9 | DB16099 | [] | [] | GAA replacement | Metabolic | Lysosomal enzyme replacement | acid-alpha glucosidase (GAA) | APPROVED | false | false | false | false | false | false | false | false | false | A16AB22 | A | A16 | A16A | A16AB | A16AB22 | Alimentary tract and metabolism drugs | Other alimentary tract and metabolism products in atc | Other alimentary tract and metabolism products in atc | Enzymes for alimentary tract and metabolism | Avalglucosidase alfa | false | null | null | false | 135 |
EC:00137 | Avanafil | CHEBI:66876 | DB06237 | [] | [] | PDE-5 inhibitor | Urological | Vasodilator | PDE-5 inhibitor | APPROVED | false | false | false | false | false | false | false | false | false | G04BE10 | G | G04 | G04B | G04BE | G04BE10 | Genito urinary system and sex hormones | Urologicals | Urologicals | Drugs used in erectile dysfunction | Avanafil | false | null | null | true | 136 |
EC:00138 | Avapritinib | UNII:513P80B4YJ | DB15233 | [] | [] | KIT / PDGFRA inhibitor | Targeted cancer therapy | Small molecule inhibitor | PDGFRA and KIT D816V inhibitor | APPROVED | false | false | false | false | false | false | false | false | false | L01EX18 | L | L01 | L01E | L01EX | L01EX18 | Antineoplastic and immunomodulating agents | Antineoplastic agents | Protein kinase inhibitors, antineoplastic and immunomodulating agents | Other protein kinase inhibitors in atc | Avapritinib | false | null | null | false | 137 |
EC:00139 | Avatrombopag | UNII:3H8GSZ4SQL | DB11995 | [] | [] | TPO receptor agonist | Hematology | Increase platelet production | TPO receptor agonist | APPROVED | false | false | false | false | false | false | false | false | false | B02BX08 | B | B02 | B02B | B02BX | B02BX08 | Blood and blood forming organ drugs | Antihemorrhagics | Vitamin k and other hemostatics | Other systemic hemostatics in atc | Avatrombopag | false | null | null | false | 138 |
EC:00140 | Avelumab | UNII:KXG2PJ551I | DB11945 | [] | [] | Anti-PD-L1 | Targeted cancer therapy | Immune checkpoint inhibitor | Anti-PD-L1 | APPROVED | false | false | false | false | false | false | false | false | false | L01FF04 | L | L01 | L01F | L01FF | L01FF04 | Antineoplastic and immunomodulating agents | Antineoplastic agents | Monoclonal antibodies and antibody drug conjugates | Pd-1/pdl-1 (programmed cell death protein 1/death ligand 1) inhibitors | Avelumab | false | null | null | false | 139 |
EC:00141 | Avibactam | CHEBI:85984 | DB09060 | [] | [] | Beta-lactamase inhibitor | Antimicrobial | Antibiotic | Beta-lactamase inhibitor | APPROVED | false | false | true | false | false | false | false | false | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | false | 140 |
EC:00142 | Avutometinib | CHEBI:78825 | DB15254 | [] | [] | MEK inhibitor | Targeted cancer therapy | Small molecule inhibitor | MEK1 and RAF inhibitor | APPROVED | false | false | false | false | false | false | false | false | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | false | 141 |
EC:00143 | Axatilimab | UMLS:C4733597 | DB16388 | [] | [] | Anti-CSF1R | Immune | Immunosuppressant | CSF-1 receptor inhibitor | APPROVED | false | false | false | false | false | false | false | false | false | L04AG19 | L | L04 | L04A | L04AG | L04AG19 | Antineoplastic and immunomodulating agents | Immunosuppressants | Immunosuppressants | Monoclonal antibodies | null | false | null | null | false | 142 |
EC:00144 | Axicabtagene ciloleucel | DRUGBANK:DB13915 | DB13915 | [] | [] | Anti-CD19 CAR-T | Cell therapy | null | Anti-CD19 CAR-T | APPROVED | false | false | false | false | false | false | false | false | true | L01XL03 | L | L01 | L01X | L01XL | L01XL03 | Antineoplastic and immunomodulating agents | Antineoplastic agents | Other antineoplastic agents in atc | Antineoplastic cell and gene therapy agents | Axicabtagene ciloleucel | false | null | null | false | 143 |
EC:00145 | Axitinib | CHEBI:66910 | DB06626 | [] | [] | VEGFR multikinase inhibitor | Targeted cancer therapy | Small molecule inhibitor | VEGFR inhibitor | APPROVED | false | false | false | false | false | false | false | false | false | L01EK01 | L | L01 | L01E | L01EK | L01EK01 | Antineoplastic and immunomodulating agents | Antineoplastic agents | Protein kinase inhibitors, antineoplastic and immunomodulating agents | Vascular endothelial growth factor receptor (vegfr) tyrosine kinase inhibitors | Axitinib | false | null | null | true | 144 |
EC:00146 | Azacitidine | CHEBI:2038 | DB00928 | [] | [] | Pyrimidine analog | Traditional cancer therapy | Antimetabolite | DNA Methylation Inhibitor | APPROVED | false | false | false | false | true | false | false | false | false | L01BC07 | L | L01 | L01B | L01BC | L01BC07 | Antineoplastic and immunomodulating agents | Antineoplastic agents | Antimetabolites | Pyrimidine analogues, antineoplastic antimetabolites | Azacitidine | false | null | null | true | 145 |
EC:00147 | Azathioprine | CHEBI:2948 | DB00993 | [] | [] | Purine synthesis inhibitor | Immune | Antimetabolite | mercaptopurine derivative | APPROVED | false | false | false | false | false | false | false | false | false | L04AX01 | L | L04 | L04A | L04AX | L04AX01 | Antineoplastic and immunomodulating agents | Immunosuppressants | Immunosuppressants | Other immunosuppressants in atc | Azathioprine | false | null | null | true | 146 |
EC:00148 | Azelaic acid | CHEBI:48131 | DB00548 | [] | [] | Azelaic acid | Dermatology | null | null | APPROVED | false | false | false | false | false | false | false | false | false | D10AX03 | D | D10 | D10A | D10AX | D10AX03 | Dermatologicals | Anti-acne preparations | Anti-acne preparations for topical use | Other anti-acne preparations for topical use in atc | Azelaic acid | false | null | null | true | 147 |
EC:00149 | Azelastine | CHEBI:2950 | DB00972 | [
"Azelastine hydrochloride"
] | [] | Histamine H1 antagonist | Immune | Antihistamine | Histamine-1 antagonist | APPROVED | false | false | false | false | false | false | false | false | false | R01AC03 | R | R01 | R01A | R01AC | R01AC03 | Respiratory system drugs | Nasal preparations | Decongestants and other nasal preparations for topical use | Antiallergic nasal preparations for topical use, excl. corticosteroids | Azelastine | false | null | null | true | 148 |
EC:00150 | Azilsartan | CHEBI:68845 | DB21772 | [
"Azilsartan medoxomil"
] | [] | Angiotensin-II receptor blocker | Cardiovascular | Antihypertensive | Angiotensin-II receptor blocker | APPROVED | false | false | false | false | false | false | false | true | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | true | 149 |
EC:00151 | Azithromycin | CHEBI:2955 | DB00207 | [] | [] | Macrolide antibiotic | Antimicrobial | Antibiotic | Macrolide | APPROVED | false | false | true | false | false | false | false | false | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | true | 150 |
EC:00152 | Aztreonam | CHEBI:161680 | DB00355 | [] | [] | Monobactam | Antimicrobial | Antibiotic | Monobactam | APPROVED | false | false | true | false | false | false | false | false | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | true | 151 |
EC:00153 | Bacitracin | CHEBI:184381 | DB00626 | [] | [] | Bacitracin | Antimicrobial; Dermatology | Antibiotic | Topical antibiotic | DISCONTINUED | false | false | true | false | false | false | false | false | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | true | 152 |
EC:00154 | Baclofen | CHEBI:187893 | DB00181 | [] | [] | GABA-B receptor agonist | Musculoskeletal | Skeletal muscle relaxant | null | APPROVED | false | false | false | false | false | false | false | false | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | true | 153 |
EC:00155 | Baloxavir | UNII:4G86Y4JT3F | DB15675 | [
"Baloxavir marboxil"
] | [] | Cap-dependent endonuclease inhibitor | Antimicrobial | Antiviral | Endonuclease inhibitor | APPROVED | false | false | true | false | false | false | false | false | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | false | 154 |
EC:00156 | Balsalazide | PUBCHEM.COMPOUND:54585 | DB01014 | [
"Balsalazide sodium"
] | [] | 5-Aminosalicylic Acid Derivative | Immune | Immunosuppressant | 5-Aminosalicylic Acid Derivative | APPROVED | false | false | false | false | false | false | false | false | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | true | 155 |
EC:00157 | Baricitinib | CHEBI:95341 | DB11817 | [] | [] | JAK inhibitor | Immune | Immunosuppressant | JAK1, JAK2 inhibitor | APPROVED | false | false | false | false | false | false | false | false | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | true | 156 |
EC:00158 | Basiliximab | UNII:9927MT646M | DB00074 | [] | [] | IL-2 receptor blocker | Immune | Cytokine therapy | IL-2 inhibitor (CD25) | APPROVED | false | false | false | false | false | false | false | false | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | false | 157 |
EC:00159 | Bazedoxifene | CHEBI:135947 | DB06401 | [] | [] | SERM | Genitourinary | Treats vasomotor symptoms and osteoporosis | selective estrogen receptor modulator | APPROVED | false | false | false | false | false | false | false | false | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | false | 158 |
EC:00160 | Becaplermin | UNII:1B56C968OA | DB00102 | [] | [] | Platelet-derived growth factor | Dermatology | Promotes wound repair | human platelet-derived growth factor | APPROVED | false | false | false | false | false | false | false | false | false | D03AX06 | D | D03 | D03A | D03AX | D03AX06 | Dermatologicals | Preparations for treatment of wounds and ulcers | Cicatrizants | Other cicatrizants in atc | Becaplermin | false | null | null | false | 159 |
EC:00161 | Beclomethasone | CHEBI:3001 | DB00394 | [
"Beclomethasone dipropionate"
] | [] | Glucocorticoid | Immune | Immunosuppressant | Glucocorticoid receptor agonist | NOT_APPROVED | false | false | false | false | false | true | false | false | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | true | 160 |
EC:00162 | Bedaquiline | CHEBI:72292 | DB08903 | [] | [] | Bedaquiline antibiotic | Antimicrobial | Antibiotic | Anti-TB | APPROVED | false | false | true | false | false | false | false | false | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | false | 161 |
EC:00163 | Belantamab mafodotin | UNII:DB1041CXDG | DB15719 | [] | [] | Anti-BCMA antibody drug conjugate | Targeted cancer therapy | Antibody drug conjugate | Anti-BCMA | DISCONTINUED | false | false | false | false | false | false | false | false | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | false | 162 |
EC:00164 | Belatacept | UNII:E3B2GI648A | DB06681 | [] | [] | Selective T-cell costimulation blocker | Immune | Immunosuppressant | Selective T-Cell costimulation blocker | APPROVED | false | false | false | false | false | false | false | false | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | false | 163 |
EC:00165 | Belimumab | UNII:73B0K5S26A | DB08879 | [] | [] | BLyS inhibitor | Immune | Immunosuppressant | Anti-BLyS (B-lymphocyte stimulator) | APPROVED | false | false | false | false | false | false | false | false | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | false | 164 |
EC:00166 | Belinostat | CHEBI:61076 | DB05015 | [] | [] | HDAC inhibitor | Targeted cancer therapy | Small molecule inhibitor | HDAC inhibitor | APPROVED | false | false | false | false | false | false | false | false | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | false | 165 |
EC:00167 | Belumosudil | UNII:834YJF89WO | DB16703 | [] | [] | ROCK2 inhibitor | Immune | Immunosuppressant | kinase inhibitor (ROCK2) | APPROVED | false | false | false | false | false | false | false | false | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | false | 166 |
EC:00168 | Belzutifan | UNII:7K28NB895L | DB15463 | [] | [] | HIF2 inhibitor | Targeted cancer therapy | Small molecule inhibitor | HIF-2alpha inhibitor | APPROVED | false | false | false | false | false | false | false | false | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | false | 167 |
EC:00169 | Bemiparin | RXCUI:2646964 | DB09258 | [] | [] | Heparin/LMWH | Hematology | Antithrombotic | Coagulation factor X antagonist | NOT_APPROVED | false | false | false | false | false | false | false | false | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | false | 168 |
EC:00170 | Bempedoic acid | CHEBI:149601 | DB11936 | [] | [] | ACL inhibitor | Cardiovascular | Lipid-lowering | Adenosine triphosphate-citrate lyase (ACL) inhibitor | APPROVED | false | false | false | false | false | false | false | true | false | C10AX15 | C | C10 | C10A | C10AX | C10AX15 | Cardiovascular system drugs | Lipid modifying agents | Lipid modifying agents, plain | Other lipid modifying agents in atc | Bempedoic acid | false | null | null | false | 169 |
EC:00171 | Benazepril | CHEBI:3011 | DB00542 | [] | [] | ACE inhibitor | Cardiovascular | Antihypertensive | ACE inhibitor | APPROVED | false | false | false | false | false | false | false | true | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | true | 170 |
EC:00172 | Bendamustine | CHEBI:135515 | DB06769 | [
"Bendamustine hydrochloride"
] | [] | Nitrogen mustard | Traditional cancer therapy | Alkylating agent | Nitrogen mustard derivative | APPROVED | false | false | false | false | true | false | false | false | false | L01AA09 | L | L01 | L01A | L01AA | L01AA09 | Antineoplastic and immunomodulating agents | Antineoplastic agents | Alkylating agents | Nitrogen mustard analogues | Bendamustine | false | null | null | true | 171 |
EC:00173 | Bendroflumethiazide | CHEBI:3013 | DB00436 | [] | [] | Thiazide diuretic | Cardiovascular | Diuretic | Active chloride reabsorption inhibitor | APPROVED | false | false | false | false | false | false | false | true | false | C03AA01 | C | C03 | C03A | C03AA | C03AA01 | Cardiovascular system drugs | Diuretics | Low-ceiling diuretics, thiazides | Thiazides, plain | Bendroflumethiazide | false | null | null | false | 172 |
EC:00174 | Benperidol | CHEBI:93403 | DB12867 | [] | [] | Typical antipsychotic | Central nervous system | Antipsychotic | Mech not known | NOT_APPROVED | true | false | false | false | false | false | false | false | false | N05AD07 | N | N05 | N05A | N05AD | N05AD07 | Nervous system drugs | Psycholeptics | Antipsychotics | Butyrophenone derivatives, antipsychotics | Benperidol | false | null | null | false | 173 |
EC:00175 | Benralizumab | UNII:71492GE1FX | DB12023 | [] | [] | Anti-IL-5 antibody | Respiratory | anti-eosinophils | Anti-IL-5 receptor antibody | APPROVED | false | false | false | false | false | false | false | false | false | R03DX10 | R | R03 | R03D | R03DX | R03DX10 | Respiratory system drugs | Drugs for obstructive airway diseases | Other systemic drugs for obstructive airway diseases in atc | Other systemic drugs for obstructive airway diseases in atc | Benralizumab | false | null | null | false | 174 |
EC:00176 | Benserazide | CHEBI:64187 | DB12783 | [] | [] | Dopa decarboxylase inhibitor | Central nervous system | Antiparkinson | Dopa decarboxylase inhibitor | APPROVED | false | false | false | false | false | false | false | false | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | false | 175 |
EC:00177 | Benzgalantamine | UNII:XOI2Q0ZF7G | DB19353 | [] | [] | Acetylcholinesterase Inhibitor | Central nervous system | Increases ACh | acetylcholinesterase inhibitor | APPROVED | false | false | false | false | false | false | false | false | false | N06DA06 | N | N06 | N06D | N06DA | N06DA06 | Nervous system drugs | Psychoanaleptics | Anti-dementia drugs | Anticholinesterase anti-dementia drugs | null | false | null | null | false | 176 |
EC:00178 | Benzhydrocodone | PUBCHEM.COMPOUND:76314940 | DB15465 | [] | [] | Opioid | Central nervous system | Analgesic | Mu-type opioid receptors | APPROVED | false | false | false | false | false | false | true | false | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | false | 177 |
EC:00179 | Benznidazole | CHEBI:133833 | DB11989 | [] | [] | Trypanosomiasis/Leishmaniasis Agent | Antimicrobial | Antiparasitic | Antitrypanosomal | APPROVED | false | false | true | false | false | false | false | false | false | P01CA02 | P | P01 | P01C | P01CA | P01CA02 | Antiparasitic products, insecticides and repellents | Antiprotozoals | Agents against leishmaniasis and trypanosomiasis | Nitroimidazole derivatives, antiprotozoal agents against leishmaniasis and trypanosomiasis | Benznidazole | false | null | null | false | 178 |
EC:00180 | Benzocaine | CHEBI:116735 | DB01086 | [] | [] | Ester local anesthetic | Peripheral nervous system | Local anesthetic | Voltage-gated sodium channel blocker | APPROVED | false | false | false | false | false | false | false | false | false | N01BA05 | N | N01 | N01B | N01BA | N01BA05 | Nervous system drugs | Anesthetics | Local anesthetics | Esters of aminobenzoic acid for local anesthesia | Benzocaine | false | null | null | true | 179 |
EC:00181 | Benzonatate | CHEBI:3032 | DB00868 | [] | [] | Peripherally acting antitussive | Respiratory | Antitussive | local anesthetic | Sodium channel inhibitor | APPROVED | false | false | false | false | false | false | false | false | false | R05DB01 | R | R05 | R05D | R05DB | R05DB01 | Respiratory system drugs | Cough and cold preparations | Cough suppressants, excl. combinations with expectorants | Other cough suppressants in atc | Benzonatate | false | null | null | true | 180 |
EC:00182 | Benzphetamine | CHEBI:3044 | DB00865 | [] | [] | Amphetamine and derivatives | Central nervous system | CNS Stimulant | Amphetamine dervative | APPROVED | false | false | false | false | false | false | false | false | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | true | 181 |
EC:00183 | Benztropine | CHEBI:94707 | DB00245 | [
"Benzatropine"
] | [] | Antimuscarinic | Central nervous system | Antiparkinson | Anticholinergic (muscarinic) | APPROVED | false | false | false | false | false | false | false | false | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | true | 182 |
EC:00184 | Benzydamine | CHEBI:94563 | DB09084 | [
"Benzydamine hydrochloride"
] | [] | NSAID | Immune | Antiinflammatory | Local anesthetic | NSAID | NOT_APPROVED | false | false | false | false | false | false | true | false | false | M02AA05 | M | M02 | M02A | M02AA | M02AA05 | Musculo-skeletal system drugs | Topical products for joint and muscular pain | Topical products for joint and muscular pain | Antiinflammatory preparations, non-steroids for topical use | Benzydamine | false | null | null | false | 183 |
EC:00185 | Benzylpenicillin | CHEBI:52139 | DB01053 | [
"Penicillin g",
"Benzathine benzylpenicillin"
] | [] | Penicillin | Antimicrobial | Antibiotic | Penicillin | APPROVED | false | false | true | false | false | false | false | false | false | J01CE01 | J | J01 | J01C | J01CE | J01CE01 | Antiinfectives for systemic use | Antibacterials for systemic use | Beta-lactam antibacterials, penicillins | Beta-lactamase sensitive penicillins | Benzylpenicillin | false | null | null | true | 184 |
EC:00186 | Bepotastine | CHEBI:71204 | DB04890 | [] | [] | Histamine H1 antagonist | Ophthalmic | Antihistamine | Histamine-1 antagonist | APPROVED | false | false | false | false | false | false | false | false | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | true | 185 |
EC:00187 | Beractant | UNII:S866O45PIG | DB06761 | [] | [] | Pulmonary surfactant | Respiratory; Neonatal | Lung surfactant | Lung surfactant | APPROVED | false | false | false | false | false | false | false | false | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | false | 186 |
EC:00188 | Berdazimer | DRUGBANK:DB18712 | DB18712 | [] | [] | Nitric oxide–releasing antiviral | Antimicrobial; Dermatology | Antiviral | molluscum contagiosum | APPROVED | false | false | true | false | false | false | false | false | false | null | null | null | null | null | null | null | null | null | null | null | false | null | null | false | 187 |
EC:00189 | Beremagene geperpavec | DRUGBANK:DB17831 | DB17831 | [] | [] | HSV-1 COL7 gene therapy | Dermatology | restoring the levels of the COL7 protein | genetically modified HSV1 delivering COL7A1 to skin cells | APPROVED | false | false | false | false | false | false | false | false | false | D03AX16 | D | D03 | D03A | D03AX | D03AX16 | Dermatologicals | Preparations for treatment of wounds and ulcers | Cicatrizants | Other cicatrizants in atc | Beremagene geperpavec | false | null | null | false | 188 |
EC:00190 | Berotralstat | UNII:XZA0KB1BDQ | DB15982 | [] | [] | Kallikrein inhibitor | Hematology | Anti-bradykinin | Kallikrein Inhibitor | APPROVED | false | false | false | false | false | false | false | false | false | B06AC06 | B | B06 | B06A | B06AC | B06AC06 | Blood and blood forming organ drugs | Other hematological agents in atc | Other hematological agents in atc | Drugs used in hereditary angioedema | Berotralstat | false | null | null | false | 189 |
EC:00191 | Besifloxacin | CHEBI:135622 | DB06771 | [] | [] | Fluoroquinolone antibiotic | Antimicrobial; Ophthalmic | Antibiotic | Fluoroquinolone | APPROVED | false | false | true | false | false | false | false | false | false | S01AE08 | S | S01 | S01A | S01AE | S01AE08 | Sensory organ drugs | Ophthalmologicals | Antiinfective ophthalmologics | Fluoroquinolone antiinfectives, ophthalmologic | Besifloxacin | false | null | null | false | 190 |
EC:00192 | Betahistine | CHEBI:35677 | DB06698 | [
"Betahistine dihydrochloride"
] | [] | Histamine analogue | Central nervous system | Antivertigo | histamine-3 antagonist | histamine-1 agonist | NOT_APPROVED | false | false | false | false | false | false | false | false | false | N07CA01 | N | N07 | N07C | N07CA | N07CA01 | Nervous system drugs | Other nervous system drugs in atc | Antivertigo preparations | Antivertigo preparations | Betahistine | false | null | null | false | 191 |
EC:00193 | Betaine | CHEBI:17750 | DB06756 | [] | [] | Glycine derivative | Metabolic | Methyl group donor for methionine | Methyl group donor for methionine | APPROVED | false | false | false | false | false | false | false | false | false | A16AA06 | A | A16 | A16A | A16AA | A16AA06 | Alimentary tract and metabolism drugs | Other alimentary tract and metabolism products in atc | Other alimentary tract and metabolism products in atc | Amino acids and derivatives | Betaine | false | null | null | true | 192 |
EC:00194 | Betamethasone | CHEBI:3077 | DB00443 | [] | [] | Glucocorticoid | Immune | Immunosuppressant | Glucocorticoid receptor agonist | APPROVED | false | false | false | false | false | true | false | false | false | H02AB01 | H | H02 | H02A | H02AB | H02AB01 | Systemic hormonal preparations, excl. sex hormones and insulins | Corticosteroids for systemic use | Corticosteroids for systemic use, plain | Glucocorticoids, systemic | Betamethasone | false | null | null | true | 193 |
EC:00195 | Betaxolol | CHEBI:3082 | DB00195 | [] | [] | Beta blocker | Cardiovascular; Ophthalmic | Antiglaucoma | Antihypertensive | Beta-1 antagonist | APPROVED | false | false | false | false | false | false | false | true | false | C07AB05 | C | C07 | C07A | C07AB | C07AB05 | Cardiovascular system drugs | Beta-adrenergic blocking agents | Beta blocking agents | Beta blocking agents, selective | Betaxolol | false | null | null | true | 194 |
EC:00196 | Bethanechol | CHEBI:3084 | DB01019 | [
"Bethanechol chloride"
] | [] | Muscarinic receptor agonist | Peripheral nervous system | parasympathomimetics | Cholinergic agonist | APPROVED | false | false | false | false | false | false | false | false | false | N07AB02 | N | N07 | N07A | N07AB | N07AB02 | Nervous system drugs | Other nervous system drugs in atc | Parasympathomimetics | Choline esters, parasympathomimetics | Bethanechol | false | null | null | true | 195 |
EC:00197 | Betibeglogene autotemcel | DRUGBANK:DB16900 | DB16900 | [] | [] | Gene therapy | Gene therapy | Gene therapy (ex vivo) | Provides functional copy of beta-globin gene | APPROVED | false | false | false | false | false | false | false | false | true | B06AX02 | B | B06 | B06A | B06AX | B06AX02 | Blood and blood forming organ drugs | Other hematological agents in atc | Other hematological agents in atc | Other hematological agents in atc | Betibeglogene autotemcel | false | null | null | false | 196 |
EC:00198 | Bevacizumab | UNII:2S9ZZM9Q9V | DB00112 | [] | [] | Anti-VEGF | Targeted cancer therapy | Monoclonal antibody therapy | Anti-VEGF | APPROVED | false | false | false | false | false | false | false | false | false | L01FG01 | L | L01 | L01F | L01FG | L01FG01 | Antineoplastic and immunomodulating agents | Antineoplastic agents | Monoclonal antibodies and antibody drug conjugates | Vegf/vegfr (vascular endothelial growth factor) inhibitors | Bevacizumab | false | null | null | true | 197 |
EC:00199 | Bexagliflozin | CHEBI:229225 | DB12236 | [] | [] | SGLT2 inhibitor | Endocrine | Antidiabetic | SGLT2 inhibitor | APPROVED | false | false | false | true | false | false | false | false | false | A10BK08 | A | A10 | A10B | A10BK | A10BK08 | Alimentary tract and metabolism drugs | Drugs used in diabetes | Blood glucose lowering drugs, excl. insulins | Sodium-glucose co-transporter 2 (sglt2) inhibitors | Bexagliflozin | false | null | null | false | 198 |
EC:00200 | Bexarotene | CHEBI:50859 | DB00307 | [] | [] | Retinoid | Targeted cancer therapy | Vitamin A derivative | Retinoic Acid Derivative | APPROVED | false | false | false | false | false | false | false | false | false | L01XF03 | L | L01 | L01X | L01XF | L01XF03 | Antineoplastic and immunomodulating agents | Antineoplastic agents | Other antineoplastic agents in atc | Retinoids for cancer treatment | Bexarotene | false | null | null | true | 199 |
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