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Which of the following findings expected on microscopic examination of biopsy from hea bowing ventricular hyperophy With asymmetric septal thickening
Patients with chronic IHD typically exhibit left ventricular hyperophy. The endocardium generally show patchy , fibrous thickening and mural thromboi may present Robbins page no. 384
2
Aschoff bodies
Disorganisation of myofibrils
infiltration by inflammatory cells
Localised fibrous scarring
Pathology
Cardiovascular system
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single
Which of the following is the mechanism of action of warfarin?
Warfarin inhibits vitamin K-dependent coagulation factor synthesis. These include factors II, VII, IX, and X, as well as protein C and S. Warfarin acts to increase the prothrombin time. Factors XI and XII are not vitamin K-dependent factors. Therefore, warfarin does not inhibit their synthesis. Activation of antithromb...
4
Activation of antithrombin lll
Fibrinolysis
Inhibition of antithrombin lll
Inhibition of synthesis of clotting factors II, VII, IX, and X
Pharmacology
null
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All of the following are the indications of non invasive ventilation except
Noninvasive ventilation (NIV) refers to the administration of ventilatory suppo without using an invasive aificial airway (endotracheal tube or tracheostomy tube). The use of noninvasive ventilation (see the video below) has markedly increased over the past two decades, and noninvasive ventilation has now become an int...
1
GCS <8
Conscious and cooperative patient
COPD
ARDS
Anaesthesia
Modes of Ventilation
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Decreased plasma renin activity is seen in:
Primary hyperaldosteronism is due to bilateral adrenal hyperplasia or due to adrenal adenoma. Both these conditions are autonomous and lead to aldosterone production in excess. The R.A.A.S system negative feedback will result in decrease in renin production. Low renin Hypeension is a feature of primary hyperaldosteroni...
1
Primary hyperaldosteronism
Baer syndrome
Pregnancy induced Hypeension
Secondary aldosteronism
Medicine
Disorders of Adrenal Gland
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single
A patient with necrotizing pancreatitis undergoes CT guided aspiration, which results in growth of E-coli on culture. The most appropriate treatment is:
Exploratory laparotomy The presence of secondary pancreatic infection suspected in patients whose systemic inflammatory response (fever, WBC count or organ dysfunction) fails to resolve, CT-guided aspiration of fluid from pancreatic bed for performance of Gram's stain & culture analysis is of critical impoance. A posit...
4
Culture appropriate antibiotic therapy
ERCP with sphincterotomy
CT guided placement of drain(s)
Exploratory laparotomy
Surgery
null
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which of the following is a SSRI
SSRI * IMPOANCE Most widely prescribed antidepressant * MECHANISM Specifically acts on serotonin transpoers and increases serotonin in synapse. DRUGS FLUOXETINE FLUVOXAMINE DAPOXETINE CITALOPRAM ESCITALOPRAM ESCITALOPRAM SERALINE PAROXETINE USE FLUOXETINE=============CHILDHOOD DEPRESSION FLUVOXAMINE===========OCD DAPOX...
2
clomipramine
fluoxetine
milnacipran
trazadone
Anatomy
Pharmacotherapy in psychiatry
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Drug used in hepatitis B infection is
Ans. is 'a' i.e., Entecavir Treatment of acute hepatitis Hepatitis B - No treatment is required. Hepatitis C - Pegylated Interferon (PEG - IFN). Treatment of chronic hepatitis Hepatitis B - Lamivudin, entecavir (preferred) or interferon. Hepatitis C - Pegylated Interferon (PEG - IFN), entecavir plus ribavirin.
1
Entecavir
Astacavir
Zanamivir
Abacavir
Pharmacology
null
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Precancerous condition of Ca stomach is -
null
2
Peptic ulcer
Chronic gastric atrophy
Achalasia cardia
Curling' s ulcer
Surgery
null
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single
Frey's syndrome is due to the involvement of-
null
1
Auriculotemporal nerve
Glossopharyngeal nerve
Vagus nerve
All
ENT
null
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multi
Commonest site of intestinal atresia is in the ?
Ans. is 'a' i.e., Duodenum
1
Duodenum
Jeiunum
Ileum
Colon
Surgery
null
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single
Which of the following is a myofunctional appliance?
Catalans or lower anterior inclined plane appliance is used to treat cross bites. The inclined plane has a 450 angulation, which forces the maxillary teeth in cross bite to a more labial position. It is teeth supported functional appliance. Expansion screw and Derichsweiler are expansion appliances.
1
Catalan's appliance
Hawley's appliance
Expansion screw
Derichsweiler appliance.
Dental
null
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An Afroamerican boy of 6 years of age presented with abdominal pain, chronic hemolysis and abnormal RBC shape on peripheral smear. Most likely disorder responsible for this condition:(AIIMS November 2014. November 2013)
Ans. a. Point mutation (Ref: Ghai 7/e p310-312; Harper's 27/e p368-371; Robbins 9/e p635-638, 8/e p646)An afroamerican kid of 6 years of age presented with abdominal pain, chronic hemolysis and abnormal RBC shape on peripheral smear. This patient is suffering from sickle cell anemia. Most likely disorder responsible fo...
1
Point mutation
Trinucleotide repeat
Antibody against RBC membrane
Genomic imprinting
Pathology
Hemolytic anemia
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Cnrnnonent of Advanced cardiovascular life suppo (ACLS) in accordance to AHA 2015 guideline:
Ans. B. Chest compression at least 5 cm/2 inchBasic life suppo (BLS), advanced cardiovascular life suppo (ACLS), and post-cardiac arrest care all describe a set of skills and knowledge applied sequentially during the treatment of patients who have a cardiac arrest.ACLS comprises the level of care between BLS and post-c...
2
Chest compression 100-150 per minute
Chest compression at least 5 cm/2 inch
Vasopressors is used to maintain MAP > 70 mmHg in non-responsive to fluids
1 Breath every 8 seconds
Anaesthesia
null
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Which of the following inhalational agent is contraindicated in a patient with history of epilepsy -
null
2
Isoflurance
Enflurane
Halothane
Sevoflurane
Anaesthesia
null
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single
For split skin graft the best source is
(A) Autograft # Autograft is skin graft taken from an uninjured part of body (e.g. thigh skin) and is used for skin grafting in same person.> It is the best skin graft for open wounds because of very high rate of successful grafting.
1
Autograft
Homograft
Isograft
Xenograft
Surgery
Miscellaneous
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The best treatment for Kawasaki disease is:
Kawasaki disease causes inflammation in the walls of medium-sized aeries throughout the body. It primarily affects children. The inflammation tends to affect the coronary aeries, which supply blood to the hea muscle. Kawasaki disease is sometimes called mucocutaneous lymph node syndrome because it also affects lymph no...
2
Aspirin
I.V. immunoglobulins
Coicosteroids
Methotrexate
Pharmacology
Immunomodulators
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single
Zafirlukast used in asthmatic patients acts by
Drugs for Bronchial AsthmaMechanism of actionDrugsBronchodilators b2 sympathomimetics Salbutamol, Terbutaline, Bambuterol, Salmeterol, Formoterol, Ephedrine Methylxanthine Theophylline, Aminophylline, Choline theophyllineAnticholinergics Ipratropium bromide, Tiotropium bromide Leukotriene antagonist Montelukast, Zafirl...
3
Phosphodiesterase inhibition
Endothelium receptor blockage
Leukotriene receptor blockage
Lipoxygenase inhibitor
Anatomy
All India exam
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single
Perforated corneal ulcer gives rise to: September 2012
Ans. A i.e. Anterior capsular cataract
1
Anterior capsular cataract
Posterior subcapsular cataract
Vossius ring
Rosette shaped cataract
Ophthalmology
null
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single
A patient develops an infection of methicillin-resistant Staphylococcus aureus. Which of the following drug cannot be used to treat the infection:
Cefaclor is a second generation cephalosporin and is not active against MRSA.
3
Vancomycin.
Cotrimoxazole.
Cefaclor.
Ciprofloxacin.
Pharmacology
null
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Generalised hypercementosis seen in:
null
1
Paget's disease
Hypothyroidism
Trauma
All of the above
Radiology
null
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multi
any behaviour that is assosiated with cessation of aversive response is called as
Behavioral therapy is learning given by BF Skinner , according to him all behaviors are learned phenomenon and thus can be unlearned Positive reinforcement a type of reinforcement when a behavior is rewarded there is more chance that the behavior is repeated Negative reinforcement is that when a behavior is done and an...
4
punishment
positive reinforcrmrnt
omission
negative reinforcement
Anatomy
Treatment in psychiatry
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multi
Pomphylox affects ?
Ans is 'a' i.e., Palms & soles POMPHOLYX An attack of pompholyx is characterized by the sudden onset of crops of clear vesicles, which appear 'sago-like'. Itching may be severe, preceding the eruption of vesicles. The attack subsides spontaneously in 2-3 weeks . In mild cases, only the sides of the fingers may be affec...
1
Palms & soles
Groin
Scalp
Trunk
Skin
null
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single
Kleine Levine syndrome is
Kleine Levin syndrome- is the best-recognized recurrent hypersomnia. It afflicts males in early adolescence. In its classic form, the recurrent episodes are associated with a) extreme sleepiness (18- to 20-hour sleep periods) b) voracious eating, c)hypersexuality, d) disinhibition (e.g., aggression). Episodes typically...
4
Insomnia
Depression
Anxiety
Hypersomnia
Psychiatry
All India exam
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single
The normal defensive mechanism for protection of gastric mucosa against acid-pepsin digestion include which of the following?
Prostaglandin is one of the impoant defensive mechanism against erosion of the gastric mucosa. Impaired production of PG will result in peptic ulcer formation. Defensive mechanisms may be divided into anatomic and physiologic types. Anatomic mechanisms are adequate blood supply, proper tight junctions between epithelia...
4
Secretion of bicarbonate into gastric mucosa
Adequate blood supply
Overproduction of PG by gastric epithelium
All of the above
Physiology
null
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multi
A 30 yrs woman 2+0, hypeension have menorrhagia. Which is best treatment for her aEUR'
MIRENA [Ref- Dewhurst text book of Gynae & Obs 7/e p. 399-404; A Comprehensive textbook of Ohs & Gynae Saillma Gupta 140, 141, 1421 The question does not give any clue regarding the aetiology of menorrhagia, so most probably the women is having D.U.B. i.e., dysfunctional uterine bleeding. When a woman present with meno...
2
Combined pills
MIRENA
Hysterectomy
Transcervical resection of endometrium
Gynaecology & Obstetrics
null
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A patient arrives in the emergency room in a coma and has a serum Ca 2+ of 4.5 mM. You sta a saline infusion of which of the following drugs
Loop diuretics such as ethacrynic acid , Furosemide increase the excretion of Ca 2+. Ref:- KD Tripathi
1
Ethacrynic acid
Calcitonin
Hydrochlorothiazide
Spironolactone
Pharmacology
Autacoids
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single
Beta-blockers are used in all of the following conditions except:-
Beta blockers are contra-indicated in AV block Beta-blockers are not given in AV blocks because they may precipitate and cause complete hea block USES OF BETA-BLOCKERS Cardiac (due to Beta 1 blockade) Extra cardiac (due to Beta 2 blockade) Hypeension PLAY : Performance anxiety , Pheochromocytoma (after a blockade) Clas...
2
Essential tremors
AV block
Angina pectoris
Migraine prophylaxis
Pharmacology
ANS
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multi
Muscle which dilates the palpebral apeure:
The levator palpebrae superioris muscle elevates and retracts the upper eyelid.
3
Orbicularis oculi
Orbicularis oris
Levator palpebrae superioris
Levator labii superioris
Anatomy
null
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single
All are seen in acute HIV syndrome Except
Clinical findings in HIV syndromeGeneralNeurologicDermatologic1. Fever2. Pharyngitis3. Lymphadenopathy4. Headache/Retroorbital pain5. Ahralgias/myalgias6. Lethargy/Malaise7. Anorexia/Weight loss8. Nausea/Vomiting/Diarrhea1. Meningitis2. Encephalitis3. Peripheral neuropathy4. Myelopathy1. Erythematous maculopapular rash...
1
Pneumonia
Lymphadenopathy
Myelopathy
Encephalitis
Medicine
Infection
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A 40 year male has Hb-10 gm%, MCV-65 fL, RDW- 16% is, Platelet count 4.5 lac/mL. Additional finding is
Serum Iron and Total Iron-Binding Capacity The serum iron level represents the amount of circulating iron bound to transferrin. The TIBC is an indirect measure of the circulating transferrin. The normal range for the serum iron is 50-150 mg/dL; the normal range for TIBC is 300-360 mg/dL. Transferrin saturation, which i...
2
Low serum transferrin
Increased iron binding capacity
Increased Hb A2
Increased Serum copper
Medicine
C.V.S
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single
O2 dissociation curve shift to right in all except
null
2
Diabetic ketoacidosis
Blood transfusion
High altitude
Anaemia
Physiology
null
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multi
Which of the following is false with regard to prevalence ?
Prevalence: Prevalence is defined as  "the total number of all individuals  who  have an attribute or disease at a  particular time  (or  during  a particular  period)  divided  by  the population at risk  of having the attribute or disease at this point in time or midway through the  period.  Although referred to as ...
3
It is a product of incidence and duration.
It can be determined by a cross-sectional studies.
It is a rate.
Prevalence is point prevalence unless otherwise specified.
Dental
null
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multi
All of the following relay in sensory cortex except
(D) Olfaction > The axons of the olfactory receptor neurons penetrate the cribriform plate and enter the olfactory bulb.> The 3 olfactory pathways that lead to the CNS are The pathway to the medial olfactory area anterior to the hypothalamus. The pathway to the lateral olfactory area of the pyriform cortex, which is th...
4
Pain
Temperature
Touch
Olfaction
Physiology
Special Senses: Smell and Taste
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multi
5HT2A antagonist drug is ?
Ans. is 'd' i.e., Ketanserin
4
Clozapine
Cisapride
Sumatriptan
Ketanserin
Pharmacology
null
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single
Topical immunomodulator used for the treatment of genital warts is :
Drugs used for viral warts (condyloma acuminata) are Imiquimod: It is an immune response modifier, useful in the treatment of external genital and peri-anal warts topi­cally. Mechanism of action against these HPV-induced lesions is unknown. 5% cream is applied 3 times weekly and washed off 6-10 hours after each applic...
1
Imiquimod
Podophyllin
Interferon
Acyclovir
Pharmacology
null
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single
Following can cause endometrial cancer:
Endometrial cancer is mainly caused by excessive estrogen Metropathia hemorrhagica is the same as cystic glandular hyperplasia and is a causative factor for endometrial cancer. Ref Dutta Gynae 5th /ed p 184 Gynandroblastoma is a virilising tumor which secretes androgens (not estrogens) and so does not lead to endometr...
1
Metropathia hemorrhagica
Gynandroblastoma
Dysgerminoma
All of the above
Gynaecology & Obstetrics
null
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multi
Beryllium expsore is associated with
Beryllium can produce a chronic granulomatous inflammatory disease that is similar to sarcoidosis.It is distinguished from sarcoidosis by evidence of a specific cell-mediated immune response(delayed hypersensitivity) to beryllium.Chest imaging shows nodules along septal lines.Pulmonary function tests show restrictive a...
2
Pulmonary fibrosis
Granulomatous lung disease
Lung cancer
Mesothelioma
Medicine
Respiratory system
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All the following are trace elements required by body except
Major elements. Trace elements 1. Calcium. 1. Iron 2. Magnesium. 2. Iodine 3. Phosphorus. 3. Copper 4. Sodium. 4. Manganese 5. Potassium. 5. Zinc 6. Chloride. 6. Molybdenum 7. Sulfur. 7. Selenium 8. Fluoride.Ref: DM Vasudevan, page no: 411
4
Zinc
Copper
Selenium
Boron
Biochemistry
nutrition and digestion
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Which type of vaccine is MMR?
ANSWER: (A) Live attenuatedREF: APPENDIX-46 below for "TYPES OF VACCINE"Live vaccines can me memorized as "BOMBEY-VT"; BCG, OPV (sabin), MMR (mumps, measles & rubella), Bubonic plague, epidemic typhus, yellow'- fever (17D), vaccinia,Oral Typhoid vaccine (Ty21a) APPENDIX - 46Types of VaccineTypeContentExamplesKilled vac...
1
Live attenuated
Killed
Toxoid
Subunit
Social & Preventive Medicine
Principles of Immunization and Vaccination
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The following host tissue responses can be seen in acute infection, except?
Ans. (d) Granuloma formationRef: Robbiris pathology 9th ed. 197* Granuloma formation is characteristic of chronic granulomatous inflammation and is not seen in acute inflammation.* Vasodilation, increase in permeability, exudation, margination, rolling etc. are seen in acute inflammation.
4
Exudation
Vasodilation
Margination
Granuloma formation
Pathology
Cellular Pathology
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Patient having fibroma of size 1.5 cm over the floor of the mouth, recommended biopsy:
null
2
Excisional biopsy
Incisional biopsy
Punch biopsy
Brush biopsy
Surgery
null
3be0217f-9e36-475e-aa48-556b229c8bc3
single
What does not make diagnosis of solitary pulmonary nodule
D i.e. Neurofibroma Primary complex in TB, produce solitary pulmonary nodule. Bronchial adenoma & Pulmonary hamaoma mostly produce solitary nodules d/ t their benign nature. Neurofibroma is almost always present at multiple foci. It is impoant to note that Hamaoma produces non cavitatory lesions.
4
Tuberculoma
Bronchial adenoma
Hamaoma
Neurofibroma
Radiology
null
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Commonest complication of parenteral nutrition includes all except: March 2007
Ans. B: Hyperkalemia Parenteral nutrition is indicated to prevent the adverse effects of malnutrition in patients who are unable to obtain adequate nutrients by oral or enteral routes. Other indications are sho gut syndrome, high-output fistula, prolonged ileus, or bowel obstruction. Sho-term TPN may be used if a perso...
2
Hyperglycemia
Hyperkalemia
Hyperosmolar dehydration
Azotemia
Surgery
null
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35-year-old c/o fever, severe abdominal pain in epigastrium radiating to the back with a h/o binge drinking. Pulse is 120 bpm, BP is 90/60 mm Hg. CT Abdomen (P+C) was done. Most likely diagnosis is(AIIMS 2016)
Ans. B Acute pancreatitisObserve a bulky pancreas with fuzzy margins and adjacent fat stranding - s/o Acute pancreatitis. CE-CT scan is IOC. Balthazar grading systemQ and CT Severity Index (CTSI)Q are used for prognosis.
2
Peptic ulcer
Acute pancreatitis
Chronic calcific pancreatitis
Acute cholecystitis
Radiology
G.I.T.
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A new born child has not passed meconium for 48 hrs. What is the diagnostic procedure of choice ?
A plain radiograph commonly shows signs of small bowel obstruction and a soft-tissue opacity. Diagnosis can be confirmed by an abdominal ultrasound scan or contrast enema. Ref: Bailey & Love&;s Sho Practice of Surgery,E25,Page-80
2
USG
Contrast enema
CT
MRI
Surgery
G.I.T
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A 25 year old male is undergoing incision and drainage of abscess under general anaesthesia with spontaneous respiration. The most efficient anaesthetic circuit is –
null
1
Maplelson A
Mapleson B
Mapleson C
Mapleson D
Anaesthesia
null
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single
Site of maximum absortion of Iron
Mnemonic Iron - Roman number One  So maximum absorption in first part of small intestine. i.e: Duodenum.
1
Duodenum
Jejunum
Ileum
Colon
Biochemistry
null
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Conn's syndrome is
Primary hyperaldosteronism (Conn's syndrome ) is defined by hypeension, as a result of hypersecretion of aldosterone. In PHA, plasma renin activity is suppressed.The most frequent cause of Primary hyperaldosteronism is a unilateral adrenocoical adenoma. Apa from hypeension, patients complain of non-specific symptoms: h...
1
Primary hyperaldosteronism
Secondary hyperaldosteronism
Primary hypoaldosteronism
Secondary hypoaldosteronism
Surgery
Endocrinology and breast
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Which of the following drugs in NOT recommended for intracheal administration during cardiopulmonary resuscitation –
Intratracheal drugs during CPR :- Adrenaline, atropine, lignocaine, naloxone.
2
Atropine
Sodium bicarbonate
Adrenaline
Lignocaine
Anaesthesia
null
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Fibrous pericardium is attached to
Fibrous pericardium base is broad and inseparably blended with the central tendon of the diaphragm.Ref: BD Chaurasia; Volume I; 6th Edition; Page no: 249
1
Central tendon
Right crus
Left crus
Pleura
Anatomy
Thorax
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single
There was a sudden increases in the size of thyroid swelling along with pain. Most likely cause is ?
Ans. is 'a' i.e., Hemorrhage within the cyst (thyroid)
1
Hemorrhage within the cyst (Thyroid)
Malignant change
Nodular goiter
Colloid goiter
Surgery
null
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single
Which of the following is the second most common congenital defect in entire spectrum of congenital deformities?
Cleft lip and palate is the most common congenital defect of facial structures and the second most congenital defect in the entire spectrum of congenital deformities (first common is clubfoot).
2
Clubfoot
Cleft lip and palate
Osteogenesis imperfecta
Ectodermal dysplasia
Dental
null
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single
Bird beak sign on barium swallow is seen in?
Ans. is 'a' i.e., Achlasia cardia * "Bird beak appearance on barium study is seen in achlasia cardia.Important esophageal signs on radiographySignConditionRat tail appearance of esophagusEsophageal carcinomaMega-esophagus (sigmoid esophagus)"Bird beak" appearanceHurst phenomenonAchlasia cardiaYo-Yo motion of barium"Cor...
1
Achlasia cardia
Carcinoma esophagus
Hiatus hernia
Nut cracker esophagus
Radiology
G.I.T.
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multi
Dietary fibre contain
Dietary fibre contains remnants of plant cells resistant to hydrolysis by the enzymes of alimentary canal. Fibre is basically composed of 2 categories : 1. Water insoluble components. 2 . Warer soluble components. 1. Water insoluble : Cellulose, Hemicellulose, Lignin 2. Water soluble : Pectins, Mucilagesn, Gums.
2
Collagen
Pectin
Proteoglycans
Starch
Biochemistry
nutrition and digestion
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single
All the follow ing are used in theTreatment of Enuresis except
(D) Spironolactone# Enuresis:> Primary Nocturnal Enuresis (PNE) is when a child has not yet stayed dry on a regular basis. Secondary Nocturnal Enuresis is when a child or adult begins wetting again after having stayed dry.> Treatment options with high success rates> Waiting Almost all children will outgrow bedwetting. ...
4
Desmopressin
Imipramine
Nortrptiline
Spironolactone
Psychiatry
Miscellaneous
364e3825-113e-416b-95af-964ffd40906a
multi
Plasrnacytoid lymphomas may be associated with -
Plasmacytoid lymphoma is lymphoplasmacytic lymphoma.Its a B cell neoplasm in adults.Most commonly the plasma cell component secretes monoclonal IgM,often in amount sufficient to cause a hyperviscosity syndrome, Waldenstrom macroglobulinemia Ref:Robbins and Cotran Pathologic basis of disease.South Asia Edition-9; volume...
2
IgG
IgM
IgA
IgE
Pathology
Haematology
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single
An 18 yrs old boy comes to the eye casualty with history of injury with a tennis ball. On examination, there is no perforation but there is hyphema. The most likely source of the blood is
.
2
Iris vessels
Circular iridis major
Sho posterior ciliary vessels
Circular iridis major
Physiology
All India exam
08930aeb-0d78-4b89-9dba-a9b60c0fa018
multi
Which of following is not a permanent mucosal fold?
Gastric rugae of the stomach and longitudinal folds in the mucosa of upper rectum and colon are temporary mucosal folds and are obliterated by distension. Whereas, plica circularis of the small intestine, crescentic mucosal folds of cystic duct (spiral valve of Heister), transverse (horizontal) rectal folds (Houston's ...
2
Spiral valve of Heister
Gastric rugae
Plica circularis
Transverse rectal fold
Anatomy
null
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single
The Hb level is healthy women has mean 13.5 g/dl and standard detion 1.5 g/dl, what is the Z score for a woman iwht Hb level 15.0 g/dl-
Ref:Parks 23rd edition pg 849 Z score = (individual value - mean) / SD =(15-13.5)/1.5= 1
4
9
10
2
1
Social & Preventive Medicine
Biostatistics
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single
True about Wegener's granulomatosis is
Triad of WG: a. Acute necrotizing granulomas of respiratory tract b. Necrotizing or granulomatous vasculitis of small to medium-sized vessels c. Focal necrotizing often crescentic GN
4
Large vessel vasculitis
Granulomas in GBM
Nephrosclerosis
Focal necrotizing GN
Physiology
All India exam
01f2b1fc-f248-4385-afef-4ee09b93044d
multi
True about GIST all except -
Ans. is 'a' i.e., Most common in duodenum o Gastrointestinal stromal tumors (GISTS) are the most common mesenchymal tumor of the GI tract and are most frequently located in the stomach (60%-70%).o In 1983, Mazur and Clark coined the term GIST to indicate a distinctive subgroup of GI mesenchymal tumor, which could be cl...
1
Most common in duodenum
Necrosis and ulceration present
PET is used to assess response to therapy
Well circumscribed
Surgery
Small Intestine - Small Bowel Tumors
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multi
Oligohydramnios is associated with :
Etiology of oligohydramnios: Intrauterine growth restriction Post-term pregnancy Premature rupture of membranes Drugs like ACE inhibitors and prostaglandin inhibitors Renal anomalies Renal Agenesis Infantile polycystic kidney disease urinary tract obstruction (refer pgno:216 Sheila 2nd edition)
2
Neural tube defects
Renal agenesis
Postmature bih
Premature bih
Gynaecology & Obstetrics
General obstetrics
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single
The property of an index to measure what is intended to measure is known as
null
1
Validity
Reliability
Quantifiabitity
Sensitivity
Dental
null
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single
Schaumann bodies are seen in
null
1
Sarcoidosis
Chronic bronchitis
Asthma
Syphilis
Pathology
null
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single
Dantrolene acts on -
Ans. is 'a' i.e., Raynodine receptor Dantroleneo Dantrolene is a directly acting skeletal muscle relaxant,o Mechanism of actionNormally excitation (depolarization of end plate) is coupled with contraction by Ca+2 - Excitation contraction coupling.Dantrolone acts on Ryanodine receptors (RyR) Calcium channels in sarcopla...
1
Raynodine receptor
Cannabinoid receptor
Both of the above
None of the above
Pharmacology
C.N.S
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multi
A study revealed lesser incidence of carcinoma colon in pure vegetarians than non-vegetarians by which it was concluded that b-carotene is protective against cancer. This may not be true because the vegetarian subjects may be consuming high fibre diet which is protective against cancer. This is an example of:
Ans is 'c' i.e. Confounding factor In an epidemiological study, in addition to the exposures that the study is investigating, there may be other factors that is associated with the exposure and independently affects the risk of developing disease. If the prevalence of these other factors differ between groups being com...
3
Multifactorial causation
Causal association
Confounding factor
Common association
Social & Preventive Medicine
Epidemiology
ec8fc07c-0015-4884-9964-31f03ca97e05
multi
Which drug is contraindicated in patients allergic to sulphonamides -
Ans. is 'c' i.e., Zonisamideo Zonisamide is a sulfonamide medication used for the treatment of seizures. It has been associated with severe skin reactions, those typically seen with sulfa reactions. This medication should not be used in sulfa-allergic patients.
3
Brizolamide
Brimonidine
Zonisamide
Bimatoprost
Pharmacology
Anti Microbial
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multi
The best prognosis in carcinoma stomach is with:
Ans. (a) Superficial spreading typeRef: Sabiston 20th Edition, Page 1214* Good prognosis is superficial spreading type and bad prognosis is Linitis Plastica type.
1
Superficial spreading type
Ulcerative type
Linitis plastic type
Polypoidal type
Surgery
Stomach & Duodenum
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single
The fouh hea sound is caused by?
A fouh hea sound is common in persons who derive benefit from atrial contraction for ventricular filling as a result of decreased ventricular wall compliance and increased resistance to ventricular filling. For example, a fouh hea sound is often heard in older patients with left ventricular hyperophy.Ref: Guyton and Ha...
3
Closureiof the aoic and pulmonary valves
Vibrations inihe ventricular wall during systole
Ventricula filling
Closure of the mitral and tricuspid valves
Physiology
Cardiovascular system
558b14f9-4957-46e1-92b3-7adf57f5324f
multi
Thyroid carcinoma with pulsating vascular, skeletal metastasis is
null
1
Follicular
Anaplastic
Medullary
Papillary
Surgery
null
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single
True about IgM is: September 2005
Ans. B: Primary response IgM is the immediate antibody that is produced once a human body is exposed to bacteria, virus or a toxin.Their demonstration in the serum indicates recent infections. IgG is found throughout the body, mainly in most of the bodily fluids, while IgM is found mainly in the blood and lymphatic flu...
2
Mediates Prausnitz-kustner reaction
Primary response
Transpoed across placenta
Secondary response
Microbiology
null
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multi
All are macrophages except-
Mononuclear macrophages o Blood macrophages → Monocytes o Tissue macrophages → Histocytes o Lung → Alveolar macrophages o Brain → Microglia o Liver → Kupjfer cells o Bone → Osteoclasts o Kidney → Mesangial cells
3
Histocytes
Kupffer cells
Lymphocytes
Osteoclasts
Pathology
null
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multi
Ascent of horse shoe shaped kidney is prevented by
Initialy in IUL(intrauterine life) kidneys are present in iliac fossa , Kidney has to reach the level of renal aery which is prevented by inferior mesenteric aery which is a branch of abdominal aoa. Fusion of right and left kidney occurs to form a U shaped structure at the level below inferior mesenteric aery.
2
Superior mesenteric aery
Inferior mesenteric aery
Superior mesenteric vein
Inferior mesenteric vein
Anatomy
GIT 1
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single
Males who are sexually underdeveloped with rudimentary testes and prostate glands, sparse pubic and facial hair, long arms and legs and large hands and feet are likely to have the chromosome complement of:
Klinefelter syndrome. Extra X chromosome, so they are 47 XXY or 46XY/47 XXY mosaics. Male phenotype Hypogonadism | Secondary sexual characteristics Dispropoionately long arms and legs.
3
45, XYY
46, XY
47, XXY
45, X0
Pathology
Genetics
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multi
Which among the following drugs is used in ectopic pregnancy?
Ans c Ref Williams Obstetrics page 247Tanaka & associates first used methotrexate to treat an interstitial preg-nancy and then it has been used successfully with ectopic pregnancy. Patient selectionInitial S. B hcg < lOOOmlU/ml-minimum failure rate size-ectopic mass<3.5cmFetal cardiac activity is a relative contraindic...
3
Mifepristone
Misoprostol
Methotrexate
Oxytocin
Surgery
Miscellaneous
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single
Features seen in a patient with chronic vomiting are all EXCEPT: March 2013
Ans. C i.e. Metabolic acidosis
3
Hyponatremia
Hypochloremia
Metabolic acidosis
Hypokalemia
Medicine
null
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multi
Antrochoanal polyp opens In which meatus:
Ans: A Middle Meatus Ref: Dhingra's ENT 6th ed./ 173-75* ANTROCHOANAL POLYP most commonly seen in children. They are unilateral, usually arises from the mucosa of maxillary antrum near its accessory ostium comes out of it & grows in the chonna & nasal cavity.* Maxillary sinus opens into the middle meatus.
1
Middle meatus
Superior meatus
Inferior meatus
Sphenoethmoidal recess
ENT
Nose and PNS
79cc1c4c-8b01-43eb-a7a6-4c103cdee3c7
single
MHC restriction is a pa of all except -
. Autoimmune disorder
4
Antiviral cytotoxic T cell
Antibacterial helper T cell/cytotoxic cells
Allograft rejection
Autoimmune disorder
Pathology
null
61965558-3501-4df7-a6ec-214bff214b60
multi
A young female presents with history of dyspnoea on exeion. On examination, she has wide, fixed split S2 with ejection systolic murmur (IIINI) in left second intercostal space. Her EKG shows left axis detion. The most probable diagnosis is :
Answer is C (Ostium primum atrial septal defect) Wide fixed splitting of S2 with ejection systolic murmur in left 2" intercostal space points towards the diagnosis of atrial septal defect.. Presence of left axis detion indicates an ostium primum 4SD. Clinical picture in ASD : Sounds S1Accentuated (Loud) S2 wide fixed s...
3
Total anomalous pulmonary venous drainage
Tricuspid atresia.
Ostium primum atrial septal defect.
Ventricular septal defect with pulmonary aerial hypeension.
Medicine
null
33b324cc-c1ee-4da4-a4b3-e04badd5b16b
single
At what gestation does the switchover from fetal to adult hemoglobin synthesis begin -
Ans. is 'b' i.e., 36 weeks Fetal Hb - (a2, g2)Adults Hb - (a2, b2,)During the initial fetal life, the major hemoglobin synthesized in the body is fetal hemoglobin, because in fetus, the chain synthesized predominantly is the g chain.b chain is present in only trace amount in early embryosThe rate of synthesis of g and ...
2
30 weeks
36 weeks
7 days postnatal
3 weeks postnatal
Pediatrics
Hematopoietic System
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single
A 40-year old male with diabetes presents with vitreous hemorrhage. What is the cause?
Ans. b. Neovascularization at disc (Ref: Kanski 5/e p447-449; Khurana 4/260-262, 3rd/256-258; Parson's 21/307, 20/e p294-299)In diabetic retinopathy, neovascularization caused by vasculoformative substance elaborated by hypoxic retinal tissue in an attempt to revascularize retina, seen especially at disc (neovasculariz...
2
Posterior retinal detachment
Neovascularization at disc
Central retinal vein occlusion
Trauma to central retinal artery
Ophthalmology
Vitreous Haemorrhage Vitrectomy
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single
Satiety centre is located at-
Ans. is 'a' i.e., Ventromedial nucleus of hypothalamus * Satiety center - Ventromedial nucleus of hypothalamus.* Feeding center - Lateral nucleus of hypothalamus.
1
Ventromedial nucleus of hypothalamus
Dorsomedial nucleus of hypothalamus
Peritrigonal area
Lateral nucleus
Physiology
Nervous System
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single
Best radiological view for diagnosis of fracture scaphoid is:
Ans. Oblique
3
Anteroposterior
Lateral
Oblique
Any of the above
Radiology
null
013c95d9-483d-4172-a023-73e2050918f5
multi
Type-I hyperlipoproteinemia is characterized by:-
Hyperlipoproeinemia Type Increased plasma lipoproteins Increased plasma lipid (most) Probable metabolic defect I Chylomicrons Triacyglycerols Deficiency of lipoprotein lipase IIa LDL Cholesterol Deficiency of LDL receptors IIb LDL and VLDL Triacylglycerols and cholesterol Overproductionn of apo-B III IDL Triacylglycero...
4
Elevated LDL
Elevated lipoprotein lipase
Elevated cholesterol
Elevated triglycerides in plasma
Biochemistry
NEET 2019
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single
Earliest finding in diabetic nephropathy
Diagnosis and screening of Diabetic nephropathy Microalbuminuria is the presence in the urine of small amounts of albumin, at a concentration below that detectable using a standard urine dipstick. Ove nephropathy is defined as the presence of macroalbuminuria (urinary albumin > 300 mg/24 hrs, detectable on urine dipsti...
4
Shrunken kidney is hallmark
Fibrin caps
Elevated serum Creatinine
Urine albumin > 300mg/ 24 hrs
Medicine
Endocrinology
c29ecf5f-4f5c-4dda-92ed-3164a9c42f20
multi
All of the following drugs are commonly used in regimens against H. pylori except -
<p>Davidson&;s principles and practice of medicine 22nd edition. *Drugs used amoxicillin,clarithromycin,metronidazole for 7 days. *Amoxicillin ,omeprazole,bismuth subcitrate and tetracycline.</p >
1
Oxytetracycline
Amoxicillin
Bismuth subcitrate
Omeprazole
Medicine
G.I.T
f4c4b6a0-8935-4f76-8800-fce01c0ac9bc
multi
According to Pugh's classification moderate to severe hepatic insufficiency is managed by ?
Ans. is 'c' ie. Ohoptic liver transplantation Child-Pugh's classification is used to assess the status of pt. of liver cirrhosis. A liver cirrhotic pt. having variceal bleeding or ascites can be controlled by shunt surgery only if he falls in ChildPugh's 'A' class (or some pts. of B class). Moderate to severe grade liv...
3
Sclerotherapy
Conservative
Ohotopic liver transplantation
Shunt surgery
Surgery
null
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single
A patient on total parenteral nutrition for 20 days presents with weakness, veigo and convulsions. Diagnosis is
Clinical features for complications of Parenteral Nutrition Hypomagnesemia Weakness, muscle cramps and tremors Marked neuromuscular and CNS hyperirritability with jerking and nystagmus Hyperkalemia Interferes with neuromuscular function to produce muscle weakness which may progress to flaccid paralysis and hypoventilat...
2
Hypermagnesemia
Hypomagnesemia
Hypercalcemia
Hypocalcemia
Anatomy
General surgery
f9ef78ff-387c-440c-acb0-35554c2681dc
single
Following are the laboratory tests for the diagnosis of vestibular dysfunction except ?
Ans. is 'd' i.e., Gelle's test Vestibular system The vestibular system contributes to balance and to the sense of spatial orientation. It is a sensory system that provides the leading contribution about movement and sense of balance. It includes the labyrinth (semicircular canals and otolith : utricle & sacules) of the...
4
Electronystagmography
Optokinetic test
Galvanic test
Gelle's test
ENT
null
58804170-9187-4c4a-b762-20200e9dc6c0
multi
The antiepileptic Drugs Which does not produce enzymes induction is:
Ref: KDT 6/e p27,408 Most anticonvulsants are enzyme inducers except valproate (inhibitor).
2
Phenobarbitone
Sodium valproate
Phenytoin sodium
Carbamazepine
Pharmacology
Central Nervous system
dd9d5a74-43b9-488f-b87f-662573c4f21a
single
Which immunogloblin is least impoant in human being -
Ans. is 'b' i.e., lgD
2
IgE
IgD
IgG
IgA
Microbiology
null
f1a4f99e-deae-4199-927f-60e8e9db4f5b
single
Mutton fat keratic precipitate is seen in -
Ans. is 'b' i.e., Granulomatous uveitis o Mutton fat keratic precipitate and Busacca's nodule are seen in granulomatous uveitis,o KPs are proteinaceous cellular deposits occuring at the back of cornea (corneal endothelial deposits).Keratic precipitates (KPs)o KPs are proteinaceous cellular deposits occurring at the bac...
2
Posterior uveitis
Granulomatous uveitis
Non-granulomatous uveitis
Choroiditis
Ophthalmology
Uveal Tract
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single
True about propofol:
B i.e. Can be used in porphyria
2
Indicated in egg allergy
Can be used in porphyria
It is of barbiturate group
All
Anaesthesia
null
7964717f-bd91-45b1-a0a0-a4722409ac57
multi
Which set of fatty acids is most effective increasing the cholesterol levels?
Lauric (12:0), myristic (14:0), and palmitic (16:0) acids raise cholesterol levels and are found primarily in animal fat and dairy products. Palmitic acid, the fatty acid that most effectively raises serum cholesterol levels, is also the major fatty acid found in palm and coconut oils. Stearic acid and fatty acids that...
2
Linoleic and linolenic
Myristic and palmitic
Butyric and stearic
Oleic and palmitic
Biochemistry
Metabolism of lipid
c690cbb9-8e89-4248-9468-f98b90763206
single
Posterior cord of brachial plexus is formed by?
Ans. is 'd'i.e., Dorsal divisions of upper, middle & lower trunks
4
Ventral division of upper trunk
Dorsal division of upper trunk
Ventral divisions of upper, middle & lower trunks
Dorsal divisions of upper, middle & lower trunks
Anatomy
null
877400a4-3e18-4da1-bf20-6c5a52597a9f
single
Which is not a side effect of dapsone ?
Ans. is 'b i.e., Myopathy Adverse effects of dapsone The most common adverse effect of dapsone is hemolytic anaemia (Patients with G-6-PP deficiency are more susceptible). Second most common adverse effect is methemoglobinemia. Other side effects are - Nausea, anorexia, headache, paresthesia, drug fever, mental symptom...
2
Hemolytic anemia
Myopathy
Hepatitis
Infectious mononucleosis type syndrome
Pharmacology
null
b7726f76-73a4-43d2-9897-4ef39ef86e60
single
Which of the following statement about the nerve supply of palate is NOT TRUE?
"Greater or anterior palatine branches of pterygopalatine ganglion supplies hard palate and lateral wall of the nose while the lesser or middle and posterior palatine nerve supply the soft palate and tonsils". All the muscles of the soft palate except tensor veli palatini are supplied by pharyngeal plexus (fibers of th...
3
Pharyngeal plexus supply muscles of soft palate
Tensor veli palatini is supplied by mandibular nerve
Anterior branch of pterygopalatine ganglion supplies soft palate
Middle and posterior lesser palatine nerves supply soft palate and tonsil
Anatomy
null
d6a05495-26cf-495f-b727-901061b6b1d2
multi
True about criggler najjar type-II syndrome is ?
Ans. is 'a' i.e., Diglucuronide deficiency
1
Diglucuronide deficiency
Recessive trait
Kernicterus is seen
Phenobarbitone not useful
Pediatrics
null
ebaef986-3ac2-446c-a316-10fda1fc1e6a
multi
A 45-year-old farmer complains of headache. Neurologic examination reveals pronator drift and mild hemiparesis on the right side. The patient's eyes and head are turned to the left side, and papilledema is visible on the left side. The lesion is most likely in which of the following coices?
Pronator drift and hemiparesis are frontal lobe signs. - Frontal eye field -> area no 8. Controls: Lateral conjugate gaze. Destruction - results in turning of the head and eyes toward the side of the lesion. Stimulation - results in contralateral turning of the eyes and head.
1
Frontal
Insular
Occipital
Parietal
Anatomy
Development of nervous system and cerebrum
a76f5d22-7c83-4d92-917e-e8dd523e4a91
single
30 years old female presents in gynaec OPD with complaints of recurrent aboions and menorahagia. Her USG showed 2 sub-serosal fibroids of 3 x 4 cm on anterior wall of uterus and fundus, which is best line of management:-
Laparoscopic myomectomy is best treatment for such young infeile patients, but it requires subserosal pedunculated fibroids and surgical expeise. Hysterectomy is advisable in patients who had completed their family. Myolysis is myoma coagulation with laparoscopic lasers. (Nd- YAG) or bipolar needle & used in perimenopa...
3
TAH with BSO
Myolysis
Myomectomy
Uterine aery embolisation (UAE)
Surgery
null
bc2461f8-6784-4deb-ab7f-faba9da7e2d4
multi