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Local anaesthetic with maximum ionized form at physiological pH ?
Ans. is 'd' i.e., Chloroprocaine Local anaesthetics with pKa value closest at physiological pH (7.4) will have a higher concentration of nonionized (unionized) base. Thus, the agent with pKa value away from physiological pH will have more concentration of ionized form. Chloroprocaine has highest pKa value, hence maximu...
4
Lignocaine
Etidocaine
Bupivacaine
Chloroprocaine
Anaesthesia
null
94a7d2ed-2ee3-4d7f-bcce-011471a891e4
single
Human hand occurs due to -
Capsicum Toxic Principle * Capsaicin * Capsicin Clinical Features 1. Dermal exposure: Burning sensation, pain * Chili burns: Person occupationally exposed to chili powder may have pain, irritation and erythema * Hunan hand: Contact dermatitis caused due to chili 2. Ocular exposure: Causes pain, lacrimation, conjunctivi...
2
Abrus prictorius
Red chilli
Dhatura
Strychnine
Forensic Medicine
Poisoning
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single
A boy attempts suicide. The boy dies due to the complications in the hospital. Doctor should:
In case of suicide, there is no need to inform the police if the person is alive. If the person dies due to complications, we should inform the police.
1
Inform police
Not required as it is a case of suicide
Repo to magistrate
Handover the body to the legal guardian
Forensic Medicine
Medical Jurisprudence
6d64321d-ad2e-407f-b331-c77e338ddeeb
single
The role played by Major Histocompatibility Complex-1 and 2 is to?
Ans. (c) Present antigens for recognition by T cell antigen receptors Ref. Ananthanarayan 9/e, p 142; Greenwood 18/e, p 106 Both Class I and Class II antigen are involved in presentation of processed antigen on microphage and other accessary cells to T-cell. Cytotoxic T-cell recognize Class I MHC antigen on target cell...
3
Transduce the signal to T cells following antigen recognition
Mediate immunogenic class switching
Present antigens for recognition by T cell antigen receptors
Enhance the secretion of cytokines
Microbiology
null
7a134787-38ae-4503-af5d-6a02991c89be
single
True about fibrates is all except:
null
3
Drug of choice for Type III hyperlipoproteinemia and severe hypertriglyceridemia
Activate PPAR to stimulate LPL
Absorbed good on empty stomach and absorption is delayed by fatty meals
Side effect are rash, urticaria, myalgia and impotence
Pharmacology
null
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multi
Diagnosis of tuberculosis in community is made by ?
<p> Diagnosis of TB is made by 2 sputum smear for AFB. Park&;s textbook of preventive and social medicine,K.Park,23rd edition,page no:429. <\p>
2
Tuberculin test
Sputum for AFB
Case fatality rate
PCR
Social & Preventive Medicine
Communicable diseases
2973dd48-9174-49e4-bc0b-25671a36d842
single
Which ahritis is common with uveitis?
Uveitis is the most common extra-aicular manifestation of AS, occurring in 20-30% of patients. The incidence is much higher in individuals who are HLA-B27 positive (84- 90%). Immune-mediated causes of uveitis Ankylosing spondylitis Behcet's disease Drug or hypersensitivity reaction Inflammatory bowel disease Multiple s...
2
RA
Ankylosing spondylitis
Still's disease
Reiter's disease
Medicine
Rheumatoid Ahritis
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single
In a child with cardiopulmonary arrest, intraosseous access should be attempted, if venous access is not available within:
a. 1 minute(Ref: Nelson's 20/e p 523-528, Ghai 8/e p 715-718)If venous access is not available within 1 minute in a child with cardiopulmonary arrest, an IO needle should be placed in anterior proximal tibia
1
1 minute
2 minutes
3 minutes
5 minutes
Pediatrics
Fluid & Electrolyte
9faeea9e-4a45-4deb-87c9-534182cf0c3c
single
Basal ganglia consist of all of the following except:
C i.e. Thalmus
3
Caudate nucleus
Putamen
Thalamus
Globus-pallidus
Anatomy
null
ae97eb0f-2126-4dbe-bb60-b1aa1434e440
multi
From which of the following aeries does the sphenopalatine aery arise?
EXTERNAL CAROTID SYSTEM 1. Sphenopalatine aery (branch of maxillary aery) gives nasopalatine and posterior medial nasal branches. 2. Septal branch of greater palatine aery (branch of max- illary aery). 3. Septal branch of superior labial aery (branch of facial aery). Ref : ENT textbook by Dhingra 6th edition Pgno : 177
3
External carotid
Facial
Maxillary
Ophthalmic
ENT
All India exam
12d79177-680a-4617-91ef-81e28e90d817
single
All are true about staing of beta-blocker therapy in a patient with congestive hea failure except:
Ref: good man and gilman, 11/e p1336 Clinical use of beta adrenergic receptor antagonistsin hea failure
1
They should be staed with optimum doses
They should be gradually increased over weeks
Special precautions should be taken in cases of NYHA class 3 and 4
Carvedilol and metoprolol are the preferred drugs
Pharmacology
Cardiovascular system
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multi
False about vaccine is -
BCG is the only widely used live bacterial vaccine. The WHO has recommended the 'Danish 1331' strain for production of the vaccine. There are 2 forms- Fresh(liquid) and freeze-dried. Ref: 25th edition, Park's Textbook of Preventive and Social Medicine, Page no. 213
4
Thiomersal is preservative in DPT vaccine
Kanamycin is preservative in measles
Magnesium chloride stabilizer used in OPV
Neomycin is a preservative in BCG vaccine
Social & Preventive Medicine
Epidemiology
315006c1-cf86-4007-8cca-4ab577f4efe4
multi
A most common cause of Neonatal Hypothyroidism is
Iodine deficiency is the commonest cause of congenital hypothyroidism in certain parts of India, while thyroid dysgenesis is the most common aetiology in non-endemic areas (75% of all cases).
1
Throid dysgenesis
Transplacental maternal thyroid antibodies
Inherited genetic disorders
Decreased thyroglubin
Pediatrics
null
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single
The drug of choice in treatment of typhoid fever in pregnancy is:
Ceftriaxone Quinolones are contraindicated in pregnancy Ref. Harrison 17/e p 958,959
4
Ampicillin
Chloramphenicol
Ciprofloxacin
Ceftriaxone
Gynaecology & Obstetrics
Medical, surgical and gynaecological illness complicating pregnancy
29e87489-43ed-498d-b560-fc571c82d125
single
Restrosternal tumor cause -
null
4
Bluish discolouration of the face
Edema of face
can occur in thyroid tumors
All
Surgery
null
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multi
Cipargamin is a drug under trial for
Cipargamin (KAE 609) is a synthetic antimalarial belonging to the spiroindolone class. In trials, it cleared the parasite rapidly in Plasmodium falciparum and Plasmodium vivax in uncomplicated Malaria patients. The safety profile of drug not known yet. Ref : Park 23rd edition Pgno : 262
4
HIV / AIDS
Tuberculosis
Typhoid
Malaria
Social & Preventive Medicine
Communicable diseases
3b781381-5510-4ac8-8fdd-5c985253b9bf
single
The age and sex structure of a population may be best described by
The age and sex composition of a country can be best described by population pyramid. Age group from 0-80+ is represented in a scale and the male and female population are represented on either side of the population pyramid. Reference: Park&;s textbook of preventive and social medicine, 23rd edition, pg no: 482,483
3
Life table
Correlation coefficient
Population pyramid
Bar cha
Social & Preventive Medicine
Demography and family planning
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single
In Troisiers sign the lymph nodes involved are
null
4
Right axillary nodes
Left axillary nodes
Right supraclavicular nodes
Left supraclavicular nodes
Pathology
null
76c37921-1baa-4541-b998-2e4dfd81a593
single
In relation to other metacarpals, the first metacarpal is
The 1st metacarpal bone (lying on a more anterior plane ) is rotated medially through 90deg relative to other metacarpals. As a result of this rotation , the movements of the thumb take place at right angles to those of other digits. B D Chaurasia 7th edition Page no : 29
2
Posterior
Anterior
Laterally rotated
Dorsally rotated
Anatomy
Upper limb
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multi
A patient of Parkinsonism, Mr. Ghai noticed that the therapeutic effect of levodopa decreased when he was given another drug by his physician but no interaction was seen when he switched over to Ievodopa-carbidopa combination. The possible drug prescribed by his physician can be:
(Ref: KDT 6/e p418, 419) Pyridoxine is a component of vitamin B complex. Pyridoxine is a cofactor for the enzyme, dopa decarboxylase and therefore, administration of vitamin B complex can stimulate the activity of this enzyme. Dopa decarboxylase conves levo-dopa to dopamine. Increased formation of dopamine in the perip...
2
Metoclopramide
Vitamin B complex
Chlorpromazine
Isoniazid
Anatomy
Other topics and Adverse effects
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single
All of the following statements about Renal physiology are true, Except
Distal tubule receives fluid from the thick ascending limb of the loop of Henle, which always contains hypotonic fluid. GFR is affected by glomerular capillary hydrostatic pressure which in turn is affected by arterial pressure, afferent and efferent arteriolar resistance. Capillaries arising from afferent arteriole fo...
2
Distal tubule always receives hypoosmotic solution
The kidneys receive 5% of the cardiac output
GFR is controlled by resistance in afferent and efferent arterioles
The Glomerulus receives capillaries from the afferent arteriole
Physiology
null
cd3f9c18-dd2e-4ca9-909c-f48c9c6d3b6b
multi
A funguicidal drug that can be used orally for the treatment of onychomycosis is
Ref-KDT 6/e 765 Fungicidal drugs are amphotericin B and terbinafine.out of these, amphotericin B cannot be given orally.thus,the and is terbinafine.
4
Griseofulvin
Amphotericin B
Clotrimazole
Terbinafine
Anatomy
Other topics and Adverse effects
b0cd3439-19f0-427d-96ae-673198f27103
multi
Consanguinity is seen with which pattern of inheritance?
Ref: Robbins E-Book, P 246* Marriage amongst cousins/close relatives is called as consanguinity.* The high consanguinity rates, could induce the expression of autosomal recessive diseases, including very rare or new syndromes.
1
AR
AD
XLR
XLD
Pathology
Genetics
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single
A 60-year-old man with a chronic cough, bloody sputum, and marked weight loss is diagnosed as having tuberculosis. A "serpentine-like" colonial morphology is noted on Lowenstein-Jensen agar. This latter finding is caused by which of the following factors
Virulence of the organism is correlated with cord factor (trehalose dimycolate).
4
A large "slimy" capsule
Wax D
Coagulase
Cord factor
Physiology
All India exam
8b4435e1-43b3-4be5-8677-ddee0bb2520b
single
Suicidal enzyme is -
Ans. is 'a' i.e., Cycloxygenase
1
C ycl oxygen ase
Lipoox ygen se
Dehydrogenase
Pyruvate kinase
Surgery
null
ba341ddc-e91d-4394-8469-86a5163e3a69
single
True regarding Japanese encephalitis are all the following EXCEPT?
Japanese encephalitis- Most common age group of children affected: 5-15 years Vector is Culex tritaeniorhynchus Permanent neurologic or psychiatric sequelae are seen Vaccine against Japanese encephalitis is available in India.
1
Children < 5 years age are most commonly affected
Transmitted by Culex tritaeniorhynchus
Permanent neurologic or psychiatric sequelae
Vaccine available in India
Pediatrics
Impoant Viral Diseases in Children
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multi
Choose the most effective drug for mild intestinal amoebiasis and asymptomatic cyst passers :
null
4
Metronidazole
Emetine
Quiniodochlor
Diloxanide furoate
Pharmacology
null
6932376e-8b1b-4e68-89b7-f3574edebee4
single
Which of the following is false regarding alpha helix?
Alpha helix is stabilized primarily by intra chain hydrogen bonds. Alpha helix is the most common and stable secondary structure. A complete turn of the helix contains an average of 3.6 aminoacyl residues. Large numbers of charged amino acids(glutamte,aspaate,histidine,lysine,and arginine) disrupt the helix by forming ...
1
Stability of an alpha helix arises primarily from the peptide bond
A complete turn of an alpha helix contains 3.6 amino acyl residues.
Pitch of the helix is 0.54nm
Large numbers of charged aminoacids such as glutamate disrupt the helix,
Anatomy
General anatomy
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multi
Non-propulsive peristalsis is a feature of
null
3
Paralytic ileus
Impacted faeces
Mesenteric vascular occlusion
Incarceration
Medicine
null
970aa467-ddcd-468e-967d-53e3851d2635
single
Which of the following inserts into the talus?
Ans. D. None of the above.The talus is made up of a head, neck, body and posterior process. It articulates with the tibia and fibula in the ankle, and the navicular and calcaneum in the foot. It has many ligamentous attachments but no muscle attachments. There is a groove posteriorly in which the flexor hallucis longus...
4
Tibialis anterior
Tibialis posterior
Extensor digitorum longus
None of the above
Orthopaedics
Miscellaneous
793e555e-11e4-4d82-ad03-88d0a4ba3c61
multi
Commonest manifestation of retinoblastoma is ?
Ans. is 'b' i.e., Leukocoria Leukocoria or amauratic cat's eye reflex this is the most common manifestation. The leukocoria or the white glow in the pupil is caused by reflection of light from the white intraocular tumor.
2
Pseudohypopyon
Leukocoria
Squint
Nystagmus
Ophthalmology
null
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single
Most common hea lesion in down syndrome
Ans. is 'a' i.e., ASD with ostium primum About 40% children with down syndrome have congenital hea disease. Endocardial cushion defect (ASD with ostium primum) account for 40-60% of cases.
1
ASD with ostium primum
ASD with ostium secundum
VSD
Coaection of aoa
Pediatrics
null
f3a6f442-442f-4365-8736-41cf3c1c1e80
single
Standard detion is measured in ?
Ans. is 'b' i.e., Dispersion
2
Distribution
Dispersion
Mean-detion
All of the following
Social & Preventive Medicine
null
701a69cb-bebe-443a-801d-e4057d81453d
multi
When two objects come in contact with each other, transfer of material takes place in accordance with:
Ans; B (Locard Exchange Principle) Locard's Exchange PrincipleQWhen any two objects come into contact, there is always a transfer of material from each object to the other. Traces from the scene may be carried away on the person or tools of crim in a l & at the same time, traces from all or any of these may be left at ...
2
Me Naughten rule: (PGI Dec 2008)
Locard Exchange Principle
Rule of Haase
Locard's method
Forensic Medicine
Law & Medicine, Identification, Autopsy & Burn
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single
Hyaline membrane is seen in: September 2011
Ans. B: Respiratory distress syndrome A homogenous eosinophilic membrane (hyaline membrane) plastering the alveolar ducts and terminal bronchioles is found in idiopathic respiratory distress syndrome HMD/ Hyaline membrane disease: Most babies with HMD shows clinical findings of respiratory distress in the delivery room...
2
Acute glomerulonephritis
Respiratory distress syndrome
Pneumonia
Cholestatic jaundice
Pediatrics
null
e5be976c-806f-4669-871d-01ff3e9b1eac
single
All of the following cranial nerves contain somatic efferent fibres except:
Facial nerve contains special branchial efferents, not somatic efferents
2
Trochlear
Facial
Abducens
Occulomotor
Anatomy
null
80b361a2-8a35-4e9e-ab89-9b51ec008b63
multi
A test for hepatitis C is performed for 200 patients with biopsy­proven disease and 200 patients known to be free of the disease. The test shows positive results on 180 of the patients with the disease, and negative results on 150 of the patients without the disease. Among those tested, this test therefore
It is given in the question, a + c (cases) = 200; b + d (healthy) = 200 And also, test shows positive results on 180 of the patients with the disease (200), so a (TP) = 180 and c (FN) = 20; and negative results on 150 of the patients without the disease, so d (TN) = 150 and b (FP) = 50
2
Has a positive predictive value of 90%
Has a sensitivity of 90%
Has a negative predictive value of 75%
Has a specificity of 82.5%
Social & Preventive Medicine
null
40cca010-f184-4054-80c6-ad57d0683ac9
single
A child came to the casualty with tetany. what will you do:
Ans: c (Inj .calcium gluconate) Ref: Nelson, 18th ed, p. 258; OP Ghai, 6th ed, p. 88Hypocalcemia may manifest with jitteriness, tetany, caipopedal spasms, laryngospasm and seizures.Signs of latent tetany(1) Trousseau's sign- caipopedal spasm of forearm and hand(2) Chovsteks sign- twitching of the orbicularis oculi and ...
3
Inj. Phenytoin
Inj. Phenobarbitone
Inj. Calcium gluconate
Wait and watch
Pediatrics
Fluid & Electrolyte
2f64b247-7449-4a30-a3f6-8ffd0d3e6a5d
single
Deep white matter lesion with bilateral deep bright thalamic appearance is suggestive of ?
Ans. is 'c' i.e., Krabbe's disease C.T. scan of leucodystrophies ? o C.T. scan of the leucodystrophies shows low density areas in the white matter which are bilateral but not necessary symmetric and becomes more extensive as the disease process progresses. Krabbe's disease On C.T, scan it shows increased density in the...
3
Alexander disease
Canavan's diseases
Krabbe's disease
Metachromatic leukodystrophy
Pediatrics
null
685a4140-40c7-47ed-9c71-7700e29d93b4
single
A 23-year-old man is admitted to the emergency department after injuring his knee while playing football. During physical examination there is pain and swelling of the knee, in addition to locking of the knee. Radiographic examination reveals a bucket-handle meniscal tear. Which of the following ligaments is most likel...
(d) Source: GAS 559, 576-577, 583, 646-647; GA 303-305 Both the medial and lateral menisci are subject to rotational injuries and may be torn. The medial meniscus is much more liable to injury because it is attached to the fused deep layer of the medial collateral ligament and joint capsule. The lateral meniscus is sep...
4
Posterior cruciate
Medial collateral
Lateral collateral
Anterior cruciate
Anatomy
Lower Extremity
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multi
Chronic discharging sinus with bone particle is seen in
Clinical features of chronic osteomyelitis The commonest presenng symptom is a chronic discharging sinus, a history of bone piece discharge from the chronic sinus is considered diagnosc of chronic osteomyelis. Pain is minimal or absent. Generalized symptoms of acute osteomyelis are not present except in acute excacer...
1
Chronic osteomyelitis
Acute osteomyelitis
Subacute osteomyelitis
Garre’s osteomyelitis
Orthopaedics
null
ec629a16-c013-4fcb-85ce-8e668b2bec5c
single
Brain tumors are best seen in which modality?
MRI is the Imaging Modality of choice for Neurological Imaging and Soft tissue evaluation Preferred investigation for Brain Tumors is a Contrast Enhanced MRI
4
USG
X-ray diffraction
CT
CE-MRI
Radiology
Magnetic Resonance Imaging
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single
Which of the following is known as 'the medical discovery of 20th century'?
Oral Rehydration Therapy (O), a cheap and effective way to tackle moality from diarrohea Hence, it is 'The medical discovery of the century' composition of Reduced Osmolarity ORS - Na+ 75 mmol /L K+ 20 mmol /L Cl- 65 mmol/L Citrate 10 mmol/L Glucose 75 mmol/L Total 245 mmol/L
3
Zidovudine
Smallpox vaccine
ORS
Penicillin
Social & Preventive Medicine
Paediatric Care in RCH: BW, BL, PEM, Breast Feeding
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multi
Immediate management of a patient with Multiple fracture and fluid loss includes the infusion -
• Resuscitation following blood loss from multiple fractures begins with administration of 2-3 liters of isotonic crystalloid immediately to restore BP and peripheral circulation. • Lactated ringer (RL) solution is generally preferred over 0.9% NaCl (normal saline) as it is balanced salt solution and designed to mimic ...
4
Blood
Dextran
Normal saline
Ringer lactate
Surgery
null
39a8c226-64a3-4b15-9801-6339cdd62b6c
single
In a patient of congenital prolonged QT syndrome and intermittent torsedes points, which of the following drug should be prescribed
Magnesium is a agent of choice for the immediate treatment of torsedes points associated with both congenital and acquired long QT syndrome . Use of intravenous isoproterenol is limited only to acquired long qt syndrome Long term treatment with oral beta blockers is required only for congenital disease Refer Goodman an...
1
Magnesium sulfate
Metaprolol
Cardiac pacing
Isoprenaline
Pharmacology
Cardiovascular system
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single
The largest ovarian tumour is seen with-
Mucinous tumor tend to produce larger cystic masses, and some have been recorded with weights of more than 25 kg.
1
Pseudomucinous cystadenoma
Serous cystadenoma
Papillary cystadenoma
Dysgerminoma
Pathology
null
8e4fea6e-a1cb-4b5a-87de-823547a09282
single
Mechanism of action of Latanoprost in glaucoma is -
Ans. is 'a' i.e., Increase the uveoscleral flow of aqueous Drugs used in open-angle glaucoma Mechanism Methods of Administration Cholinomimetics Pilocarpine, carbachol, physostigmine, echothiophate, demecarium Ciliary muscle contraction, opening of the trabecular meshwork, increased outflow Topical drops of gel; plasti...
1
Increase uveoscleral flow of aqueous
Trabecular absorption is increased
Decreases aqueous formation
All of the above
Pharmacology
A.N.S.
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multi
Glutathione requires which vitamin to act as antioxidant
Glutathione peroxidase: It detoxifies H2O2 to H2O, while reduced glutathione (G SH) is conveed to oxidized glutathione (GS SG). The reduced glutathione can be regenerated by the enzyme glutathione reductase utilizing NADPH The hexose monophosphate shunt is the major source of NADPH. ref Satyanarayana 4th ed page 659
2
Vitamin E
Niacin
Vitamin C
Vitamin A
Biochemistry
vitamins
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single
Exception of Meyer oveon rule are A/E
D i.e. Hydrophobic site Non anesthetics/ nonimmobilizers, cut off effect convulsant gases, isomers, hydrophilic site and critical volume expanism hypothesis provide exceptions to the meyer - oveon ruleQ.
4
Nonanaesthetics
Nonimmobilizer
Cut off effect
Hydrophobic site
Anaesthesia
null
7935bb07-ef65-4cc8-afb2-4de8bc22b98b
multi
Hand-knee gait is seen in patients of: March 2013 (b, e)
Ans. C i.e. Polio Hand knee gait Extend of the paralysis in the lower limbs determines the walking ability of the patient with poliomyelitis. When one leg has a normal or nearly normal muscles power, and some residual power in the antigravity muscles (gluteus maximus, quadriceps, and triceps surae) of the other limb, t...
3
Leprosy
TB
Polio
Common peroneal nerve palsy
Surgery
null
177d2d4c-8688-4383-8a6c-45e08ff5a4af
single
Spiegelberg criteria is used for the diagnosis of:
Ans. B. Ovarian pregnancyThe most common site of ectopic pregnancy is fallopian tube. Ectopic at other sites is secondary to ruptured ectopic from fallopian tube unless proved otherwise. The criteria defining primary ectopic at these uncommon sites are as followsRubin's----primary cervical, Spiegelberg----primary ovari...
2
Tubal pregnancy
Ovarian pregnancy
Cervical pregnancy
Abdominal pregnancy
Gynaecology & Obstetrics
Ecotopic Pregnancy
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single
In each freshwater drowning the death occurs within 4-5 minutes of submersion due to ventricular fibrillation. Which of the following reasons is responsible for this?
D i.e. Hemodilution, overloading of hea and hemolysis resulting in release of potassium
4
Total asphyxia is produced due to fresh water
Laryngospasm causing vagal inhibition
Haemoconcentration of blood caused by the osmotic pressure effect
Haemodilution, overloading of hea and haemolysis resulting in release of Potassium
Forensic Medicine
null
c347c1c4-04d4-4aac-a8ee-ede5fdf4b349
single
A person with type 1 diabetes ran out of her prescription insulin and has not been able to inject insulin for the past 3 days. The patient is hyperventilating to compensate for her metabolic acidosis. Which of the following reactions explains this partially compensating respiratory alkalosis?
The patient is "blowing off CO2 " to reduce acid. The equation described in answer C is the conversion of carbon dioxide into a soluble form, then into bicarbonate. During an acidosis, the high levels of protons push the reaction described in answer C to the left, to the formation of water and carbon dioxide. As the ca...
3
H+NH3=NH4+
CH3CHOHCH2COOH=CH3CHOHCH2COO-+H+
CO2+H2O=H2CO3=H++HCO3-
H2O=H++HO-
Biochemistry
Miscellaneous (Bio-Chemistry)
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multi
α and β subunits are not seen in:
hCG (Human chorionic gonadotropic hormone) has alpha and beta subunits. Its alpha subunit is similar to that of LH (leutinizing hormone), FSH (Follicular stimulating hormone) and TSH (Thyroid stimulating hormone) whereas beta subunits is specific. We have also studied that insulin hormone has alpha and beta subunits. R...
3
FSH
HCG
Prolactin
Insulin
Gynaecology & Obstetrics
null
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single
Herbert's pit is seen in:
Ans: D (Chlamydial conjunctivitis) Ref Parsons Diseases of the Eye : 21st edition: pg no -- 172-175Explanation:TRACHOMA:Caused by Chalmydia trachomatis A, B, Ba, CSpread by 3Fs - Fingers, Fomites. FliesForms epithelial inclusion bodies - Halberstader Prowazek Inclusion BodiesConjunctiva - upper tarsal follicle which he...
4
Vernal conjunctivitis
Atopic conjunctivitis
Gonococcal conjunctivitis
Chlamydial conjunctivitis
Ophthalmology
Inflammations of Conjunctiva - Infective
841cc970-2fe9-4544-9fc0-24501221a5df
single
Quality control agent for Sterilization in Autoclave
Autoclaving Geobacillus stearothermophilus(GBS) Hydroclaving Bacillus subtilis Microwaving Bacillus atrophaeus Dry heat GBS or Bacillus atrophaeus
3
Bacillus subtilis
Bacillus pumilus
Bacillus stearothermophilus
Bacillus globigi
Social & Preventive Medicine
Biomedical Waste Management
7e13f63b-98aa-4207-8227-45e3ae6aaabf
single
Coloured urine is not seen in:
All the drugs mentioned above are associated with coloured urine. Though quinine may cause dark colored urine, its relatively rare compared to the other drugs given in the option. So quinine is the single best answer of choice by exclusion. Ref: Textbook of Medical Laboratory Technology By Sood, Page 36; Harrison's Pri...
1
Quinine
Rifampcin
Nitrofurantoin
Pyridium
Medicine
null
4becc129-124e-4e74-b377-9426bb0a1a79
single
Schizopherenia is characterized by :
D i.e All- Schizophrenia is a formal thought disorderQ, characterized by third person hallucinationQ & inappropriate emotion (affect).- Delusion (primary autocanthous)Q is a Schneider's first rank symptom of schizophrenia.- Altered consciousness (sensorium) is a characteristic feature seen in deliriumQ (not in schizoph...
4
Formal through disorder
Hallucination
Delusion
All
Psychiatry
null
275d5823-7604-4607-b8f1-693ae9bc9a8f
multi
Which one of the following is NOT an absolute contraindication for oral contraceptive pills?
Contraindications for use of oral contraceptive pills (OCPs):
4
Cancer of breasts
Cardiac abnormalities
History of thrombo-embolism
Nursing mothers
Social & Preventive Medicine
null
3cb32383-5fe4-4abd-ac98-e6266dc6b3e0
single
The following condition is not associated with an Anti- phopholipid syndrome -
Ans. is 'c' i.e., Thrombocytosis
3
Venous thrombosis
Recurrent foetal loss
Thrombocytosis
Neurological manifestations
Pathology
null
14570ef5-7151-421a-b1a4-9cf535ae165b
single
Referred otalgia can be due to?
ANSWER: (D) All of the aboveREF: Dhingra 4th ed p. 124Causes of referred otalgiaEar receives nerve supply from Vth (auriculotemporal), IXth (tympanic br.) and Xth (auricular br.) cranial nerves; and from C2 (lesser occipital) and C2 and C3 (greater auricular), pain may be referred from these remote areasVia Vth cranial...
4
Carcinoma larynx
Carcinoma oral cavity
Carcinoma tongue
All of the above
ENT
Miscellaneous Ear
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multi
Water-shed area of inferior mesenteric aery and internal iliac aery lies at
Sudeck's point is an area prone to ischemia where anastomoses between distal branches of inferior mesenteric aery and internal iliac aery occurs which gives middle and inferior rectal aery which supplies pelvis and perineum. Griffiths' point is defined as the site of (a) communication of the ascending left colic aery w...
4
Griffith's point
Sigmoid colon
Anorectal junction
Sudeck's point
Anatomy
Stomach and aerial supply of abdomen
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single
True regarding water absorption in tubules:September 2007
Ans. B: Bulk of water reabsorption occurs secondary to sodium absorptionWater reabsorption keeps pace with the sodium reabsorption in the proximal tubules and hence the concentration of sodium and total osmolarity remains the same.
2
Majority of facultative reabsorption occurs in proximal tubule
Bulk of water reabsorption occurs secondary to sodium absorption
25% of water is reabsorbed irrespective of water balance
Obligatory reabsorption is ADH dependent
Physiology
null
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multi
Extensive involvement of deep white matter with bilateral hyperdense thalami on non-contrast CT scan of the brain is virtually diagnostic of -
Extensive involvement of deep white matter with bilateral hyperdense thalami on CT scan suggests the diagnosis of Krabbe's disease.
2
Alexander's disease
Krabbe's disease
Canavan's disease
Metachromatic leukodystrophy
Radiology
null
9366bfca-ddb7-4761-9901-a4f2eb4b5fef
multi
Milestone of 18 month old child includes ___________
Developmental milestones:- GROSS MOTOR DEVELOPMENT: 2 months: Holds head in plane of rest of the body when held in ventral suspension. In prone position in bed, the chin lifts momentarily. 3 months:lift head above the plane of the body. Head control stas by 3 months and fully developed by 5 months. 4 months:Remain on f...
2
Knows gender
Ten words
Rides tricycle
Climbs steps
Pediatrics
Growth and development
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multi
False about pre - styloid space
Prapharyngeal space on basis of styloid is divided into i) Prestyloid compartment Has maxillary Artery has branches of mandibular nerve ii) Post styloid compartment Has ICA IJV 9,10,11,12 cranial nerve
3
Is anterior compartment of Para pharyngeal space
Contains maxillary artery
Contains maxillary nerve Branches
Contains mandibular nerve branches
ENT
null
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multi
Enzyme responsible for conversion of androgen into estrogen -
Ans. is 'a' i.e., Aromatase o Estradiol is the major estrogen secreted by the ovary.o It is synthesized in the graffian follicle, corpus luteum and placenta from cholesterol.o Estradiol is rapidly oxidized in liver to estrone which is hydroxylated to form estriol.
1
Aromatase
Sulphatase
Fumarase
3 beta hydroxy steroid dehydrogenase
Gynaecology & Obstetrics
Endocrine Control of the Menstrual Cycle
384b7aa1-89ff-4ee4-9a40-d72aade57e24
single
The first sign of pubey in female is
Thelarche is the first sign of pubey in a girl around the age of 10 yearsDefinition:- beginning of secondary (Postnatal) breast development at the onset of pubey in girlsTanner stage 2 breast development.Because of rising level of estradiol.Breast development in a male is termed as gynecomastia, not thelarche(Refer: Ne...
2
Tanner stage I
Tanner stage II
Pubic hair
Axillary hair
Pediatrics
All India exam
b1ff71eb-b907-4b72-b43c-79719fe2358c
single
Feature of microscopic polyangitis is -
Ans. is 'c' i.e., Renal involvementMicroscopic polvangitis (MPA)It is a necrotizing vasculitis.o It is considered as a variant of polyaeritis nodosa (PAN), but in contrast to classical PAN, microscopic polyangitis involves smaller vessels, i.e. aerioles, venules and capillaries.o It is also differentiated from classica...
3
IgG deposits in kidney
Bronchospasm
Renal involvement
All of the above
Pathology
null
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multi
Most commonly performed hepatobiliary shunt in Budd-Chiari syndrome
Treatment Side-to-side poocaval shunt: SSPCS is the most effective therapy for BCS caused by thrombosis of the hepatic veins Ideal circumstances for shunt surgery include in BCS Absence of cirrhosis or significant fibrosis on biopsy Absence of a significant gradient between the Supra hepatic and Infra hepatic IVC Relat...
4
Rex shunt
Lienorenal shunt
Mesocaval shunt
Side-to-side poocaval shunt
Anatomy
G.I.T
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single
Teriparatide is used in treatment of:
Ans. A. OsteoporosisTeriparatide is recombinant PTH. It is given in osteoporosis as it increases the new bone formation and increase the bone mineral density.
1
Osteoporosis
Breast cancer
PCOD
Hyperthyroidism
Pharmacology
Endocrinology
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single
Complication of neck femur fracture are all except-
*Impoant complications of fracture femoral neck are AVN of femoral head ( most common ), nonunion and secondary osteoahritis. *AVN is the most common complication of femoral neck fracture. M/c affects => Femoral Head M/c site => Anterolateral aspect (Being principal Wt. bearing poion) Incidence&;d/t t Steroid usage & T...
2
Nonunion
Malunion
AVN
Osteoahritis
Orthopaedics
Pelvis and Hip injuries
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multi
In 4 split skin smears of a patient, 2 samples had 10 bacilli out of 100hpf and 2 samples with > 1000 bacilli. Average bacteriological index would be
RIDLEY'S LOGARITHMIC SCALE FOR BACTERIAL INDEX Bacterial/ Bacteriological Index (BI) : Density of bacilli in smears, including both living and dead bacilli. Ridley's logarithmic scale : Based on the number of bacilli seen in an average High power microscopic field, using an oil-immersion objective (1/12 in or 2 mm) Whe...
1
3.5
4.5
5.5
6.5
Social & Preventive Medicine
Communicable diseases
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single
Sub periosteal hemorrhage is seen in: (Repeat)
Ans: A (Vitamin C deficiency) Ref: Nelson's Textbook of Pediatrics. 19th Edition, Page 198Explanation:Radiographic Changes in ScurvyThe typical radiographic changes occur at the distal ends of the long bones and are particularly common at the knees.The shafts of the long bones have a ground- glass appearance due to tra...
1
Vit C deficiency
Vit A deficiency
Vit E deficiency
Vit B2 deficiency
Pediatrics
Vitamin C
ceaa98db-fabd-4a20-98ad-4bdc5b58ff94
single
Which of the following ECG changes in an Asymptomatic Athlete's Hea should be considered pathological'?
Answer is B (Second Degree (Mobitz 2) hea block) Second Degree (Mobitz 2) hea block should he considered a pathological finding in an Athletes Electrocardiogram. `Various degrees of atrioventricular blocks have been described in endurance athletes. First Degree Blocks and Second Degree (Mobitz Type- 1) are a common fin...
2
Increased amplitude of QRS
Second Degree (Mobitz 2) hea block
Prominent U Waves
T Wave inversion
Medicine
null
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single
The use of combined oral contraceptive pill is associated with an increased incidence of
Ans. is b i.e. Chlamydial endocervicitis This is a tricky question as some believe Option "b should be the answer while others believe Option "c" should be concerned. As far as candidial (monilial) vaginitis is concerned, OCP's use increase their incidence. But for Chlamydial infections : "Persons who use barrier contr...
2
Bacterial vaginosis
Chlamydial endocervicitis
Vaginal was
Genital herpes
Gynaecology & Obstetrics
null
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single
A-H interval on ECG is for conduction -
Ans. is 'b' i.e., From AV node to bundle of Hiso Certain intervals are measured to provide information regarding AV block.PA interval: It is time taken from onset of P-wave to onset of deflection in atrial catheter. It is an index of intra-atrial conduction. Normal vlaue is less than 55 mS.AH interval : it represents c...
2
Through His-Purkinje system
From AV node to bundle of His
From Purkinje system to ventricular fibres
Through ventricular fibers
Unknown
null
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single
OCD is associated with which personality?
Ans. is 'a' i.e., Anankastic Obsessive-Compulsive (anankastic) personality disorder : - People with obsessive-compulsive personality disorder are markedly preoccupied with orderliness, perfectionism, and control. They lack flexibility or openness. Their preoccupations interfere with their efficiency despite their focus...
1
Anakastic
Borderline
Narcissistic
Histrionic
Psychiatry
null
45a6bea5-018b-41f0-8654-5b4efc2eb174
single
Barr body is absent in female having ?
Ans. is 'b' i.e., 45 X0 genome Barr body (Sex - chromatin) o It is a densely staining inactivated condensed 'X' chromosome that is present in each somatic cells of female. o It is found in the nucleus. o It is used as a test of genetic femaleness it is possible to determine the genetic sex of an individual according as...
2
46 XX genome
45 X0 genome
47 XXX
All of above
Pediatrics
null
f926e4b5-a7e6-48f8-8872-df1e4ad1c043
multi
All the following are true about Papilledema except-
There is gradual painless loss of vision Papilloedema is non- inflammatory edema of optic disc. Visual symptoms (only in 25% of patients) start as transient obscurations of vision. Earliest ophthalmoscopic sign is blurring of the margins of the optic disc, which starts at the upper and lower nasal margins and entends t...
4
It is a purely non-inflammatory phenomenon
Transient loss of vision occurs
First sign is blurring of the nasal side of the optic disc
Sudden loss of vision with painful eye movement
Ophthalmology
null
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multi
Recurrent miscarriage is :
Ans. is 'b' i.e., 3 or more consecutive losses < 20 weeks * Recurrent miscarriage, habitual abortion, or recurrent pregnancy loss (RPL) is three or more consecutive pregnancy losses at less than (or equal to) 20 weeks of gestation or with a fetal weight of <500 grams.* It affects approximately 1% to 2% of women
2
4 or more pregnancy losses at any weeks
3 or more consecutive losses < 20 weeks
>2 pregnancy losses >12 weeks
>3 pregnancy losses, after 24 weeks
Gynaecology & Obstetrics
Medical & Surgical Illness Complication Pregnancy
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single
What will not help in reducing discoloration of amalgam restored tooth?
null
2
Well condensation
Void in restoration
Use of varnish on the walls prior to insertion of amalgam
Use of varnish over the restoration
Dental
null
bcaaa558-465f-44f7-b8fa-09cd3be65b64
multi
A 55-year-old female presents with tinnitus, dizziness and history of progressive deafness. Differential diagnosis includes all except:
Acoustic neuroma and endolymphic hydrops (Meniere's syndrome) present with tinnitus, dizziness and progressive hearing loss. This also holds true for meningiomas which involve cerebellopontine (CP) angle. Nearly 10% of tumors of CP angle are meningiomas.Histiocytosis X. presently called Langerhans cell histiocytosis, i...
4
Acoustic neuroma
Endolymphatic hydrops
Meningioma
Histiocytosis X
ENT
Ear
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multi
Bad prognosis in AML is indicated by aEUR'
Monosomy Prognostic factors in AML Favourable prognostic factors Unourable prognostic factors Miscellaneous prognostic factors * Age < 40 yrs * del (7q) * In recent years, with availability * AML without antecedent MDS/ MPD * dui (5q) of markers on bone marrow * Blast cells with Auer rods * 11q23 - MLL +ve trephine sec...
1
Monosomy
Deletion of X or Y chromosome
T (8 : 21)
Nucleophosmin mutation
Surgery
null
ad98e47b-48cc-4532-9a84-67f93e507ae0
single
Make the diagnosis of a 26 day old Infant presenting with recurrent nonbilious vomiting with costipation and loss of wt:
Ans. is 'd' ie Pyloric stenosis.This is a typical picture of pyloric stenosisInfant presenting in 4 th weekNon-bilious vomitting.With constipation and wt. loss.Lets see other options.Esophageal atresiaInfant presents soon after birth with complaints of regurgitation of milk, saliva pours almost continuously from its mo...
4
Oesophageal atresia
Choledochal cyst
ileal atresia
Pyloric stenosis
Surgery
Benign Gastric Disease
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single
A 60 year old man is suspected of having bronchogenic ca: TB has been ruled out in this pt. What should be the next investigation
Answer is B (Bronchoscopy and biopsy) : Fibreoptic bronchoscopy with a brochial or transbronchial biopsy is the better option here as it also allows direct visualization of the tumor mass 'The screening of lung cancer by means of sputum cytology & chest radiographs is not very effective'-H1401/255 Once signs/symptoms o...
2
CT guided FNAC
Bronchoscopy and biopsy
Sputum cytology
X-Ray chest
Medicine
null
9973eaa2-316e-48e5-bce9-1ba55eb08857
single
The characteristics of polio vaccine are all except?
Ans. is 'b' i.e., 100% immunization In OPV, the viruses multiply in the gut and the vaccine progency is excreted in the feces and secondary spread occurs to house hold contacts and susceptible contacts in the community. Non-immunized person may therefore, be immunized. Thus widespread herd immunity results, even if onl...
2
Maintenance of cold chain
100 % immunisation
Killed vaccine is effective in India
5 doses of OPV given
Social & Preventive Medicine
null
01c9f3a5-664d-4a6c-a4ab-48cae77158ce
multi
According to WHO leprosy is a public health problem if prevalence is more than:
At the end 2000, leprosy was a public health problem in 10 countries (prevalence rate > 1/10,000), mainly in Africa, Asia and Latin America. Thus to call it a public health problem prevalence per 10,000 should be more than 1 and per 100 should be > 0.01.
2
0.10%
0.01%
0.50%
1%
Unknown
null
b5a8cc2e-5482-48e1-bf90-ee4171b45760
single
Type of exercise done to increase the muscle strength:September 2005
Ans. C: IsotonicWhile isometric training increases strength at the specific joint angles of the exercises performed and additional joint angles to a lesser extent, dynamic exercises increase strength throughout the full range of motion.Generally speaking however, people who train isometrically don't train through a ful...
3
Aerobic isotonic
Isometric
Isotonic
All of the above
Physiology
null
c0750fc2-1b72-4f7f-ad10-4879da787be6
multi
Parenteral direct thrombin inhibitor?
Ans. is 'c' i.e., Argatroban
3
Ximelagatran
Dabigatran
Argatroban
Heparin
Pharmacology
null
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single
Most common cause of esophageal perforation at the site of cricopharynx -
Ans. is 'b' i.e., Iatrogenic o Oesophageal perforation is of two types :Iatrogenic (MC)Common site is cervical esophagus Just above the upper sphincter.Spontaneous rupturey As seen in Boerhaaves syndrome (Rupture of esophagus after vomitting).Common in the lower 1/3 of esophagus.
2
Spontoneous
Iatrogenic
Traumatic
null
Surgery
Esophageal Perforation
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multi
Asmann psychrometer is useful for -
A psychrometer is an instrument to measure the humidity of the air. Assmann psychrometer is a poable instrument to give accurate readings of wet and dry bulb temperatures of air. In this instrument, the air is drawn at a speed of 5 meters per second by clockwork fan. Park's Textbook of Preventive and Social Medicine, 2...
1
Humidity
Velocity
Temperature
Sound intensity
Social & Preventive Medicine
Environment and health
0ca8b50c-698d-4e86-be06-080a90200362
single
The auriculotemporal nerve encircles which of the following vessels?
After branching from the mandibular nerve (CN V3), the auriculotemporal nerve travels posteriorly and encircles the middle meningeal artery, remaining posterior and medial to the condyle. It then continues up towards the TMJ,external ear, and temporal region, passing through the parotid gland and traveling with the sup...
4
Maxillary artery.
Superficial temporal artery.
Deep auricular artery.
Middle meningeal artery.
Anatomy
null
23f453ab-caa4-4ddd-8ead-ecb43a834916
single
Unilateral middle ear serous effusion in an adult, most common cause ?
Ans. is 'c' i.e., Nasopharyngeal carcinoma "In adults presenting with a unilateral middle ear effusion the possibility of a nasopharyngeal carcinoma should be considered-- Current otolaryngology 2"d/e p. 659 "A high incidence of NPC (Nasopharyngeal carcinoma) in South East Asia and Southern China correlates with the hi...
3
TB
Foreign body
Nasopharyngeal carcinoma
CSOM
ENT
null
a85a5ab1-e2f6-4f89-8d94-f56e6d4a6ccd
single
30 yrs female presented with unilateral breast cancer associated with axilary lymph node enlargement. Modified radical mastectomy was done, fuhur traeatment plan will be
. Chemotherapy in Carcinoma Breast (Indications) * In advanced carcinoma breast as a palliative procedure. * In postoperative period after simple mastectomy in stage III carcinoma breast with fixed axillary nodes. * In inflammatory carcinoma of breast. * In stage IV carcinoma breast with secondaries in bone, lungs, liv...
2
Observation and followup
Adriamycin based chemotherapy followed by tamoxifen depending on estrogen\/progesterone receptor status
Adriamycin based chemotherapy only
Tamoxifen only
Surgery
Endocrinology and breast
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single
An 18-year-old woman comes to the emergency room with recurrent facial edema, especially around her lips. She also has recurrent bouts of intense abdominal pain and cramps, sometimes associated with vomiting. Laboratory examination reveals decreased C4, while levels of C3, decay-accelerating factor, and IgE are within ...
This  women is suffering from hereditary angioedema. C1 inhibitor blocks the activation of C1, the first protein of the classical complement pathway. Inherited deficiency of this inhibitor is the cause of hereditary angioedema. Deficiency of decay accelerating factor (DAF), which breaks down the C3 convertase complex, ...
1
C1 esterase inhibitor
Complement components C3 and C5
Decay-accelerating factor
None of the above
Pathology
null
2b40ffa1-f626-4c84-bb60-43347e1f45a2
multi
"Onion skin" fibrosis of bile duct is seen in-
null
2
Primary biliary cirrhosis
Primary sclerosing cholangitis
Extrahepatic biliary fibrosis
Congenital hepatic fibrosis
Pathology
null
fb817e43-df69-42d1-894d-03a7d2a7303c
single
A 55ps old male presents with tachypnea and mental confusion. Blood glucose 350mg/dL pH 2.7 What is the most likely acid base disorder
The condition of patient is D K A ref : harrisons 21st ed
3
metabolic alkalosis
Respiratory alkalosis
Metabolic acidosis
Respiratory acidosis
Medicine
All India exam
02f84b59-a2d6-4655-8529-31acb9fdba40
single
Management in case of rupture of disc at L5, S1 is
C i.e. Immobilization for 2 weeks with spinal brace
3
Emergency removal of disc
Joint fusion
Immobilization for 2 weeks with spinal brace
Traction
Surgery
null
1e58c9fe-af39-46e2-870d-5f67fecebdc2
single
Carpel tunnel syndrome is due to compression of -
Carpal tunnel syndrome occurs when the median nerve is compressed in the carpal tunnel below flexor retinaculum.
4
Radial nerve
Ulnar nerve
Palmer branch of the Ulnar nerve
Median nerve
Orthopaedics
null
ba9d8012-8259-4a60-a6ff-436e2fa96237
single