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Antigliadin antibodies are delectable in -
Anti-gliadin antibodies were one of the first serological markers for coeliac disease. Problematic with AGA is the typical sensitivity and specificity was about 85% Ref Davidson edition23rd pg 806
3
Tropical sprue
Whipple's disease
Celiac disease
Intestinal lymphoma
Medicine
G.I.T
d35133c3-918f-4a7b-b395-d29ac9f32591
single
Which of the following is iron chelator:
Ans. A. DesferrioxamineEDTA is used for Manganese, iron, lead, bismuth. BAL is used for bismuth arsenic and lead. Penicillamine is used for copper poisoning. Dessferrioxime is iron chelator.
1
Desferrioxamine
EDTA
BAL
Penicillamine
Pharmacology
Chelating Agent
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single
A child presents with stridor, barking cough and difficulty in breathing since 2-3 days. He has fever and elevated leukocyte count. All of the following statements about his condition are true, EXCEPT:
null
4
Subglottis stenosis and hypopharyngeal dilatation may be seen on X-rays
Boys are more commonly affected than girls
Symptoms are predominantly caused by involvement of the subglottis
Antibiotics form the mainstay of treatment
ENT
null
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multi
PACS in medical imaging stands for:
C i.e. Picture archiving communication system Picture archiving & communication system (PACS) makes hospitals filmless; as it uses digital imaging modalities like ultrasound, CT, MRI and digital x-ray (rather than traditional x ray films). Electronic patient record (EPR) or Electronic medical record (EMR) accommodate e...
3
Poal Archiving Common System
Photo Archiving Computerized System
Picture archieving communication system
Planning archiving communication scheme
Radiology
null
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single
An 8 days old neonate presents with hypoglycemia (Glucose - 17 mg%) and jaundice is diagnosed to have metabolic disorder. Most likely diagnosis:
B i.e. GalactosemiaRef: Nelson, Textbook of Pediatrics, 20th edition, page 726/Manuai of Neonatal Care, ClohertyExplanation:GalactosemiaDue to deficiency of galactose-1-phosphate uridyltransferase (GALT).Newborn develop symptoms after ingestion of lactose (glucose-galactose disaccharide) through a standard formula or b...
2
Hypothyroidism
Galactosemia
Glycogen storage disease
Fatty acid oxidation defect
Pediatrics
Inborn Errors of Metabolism
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Which of the following is not an appropriate investigation for anterior urethral stricture ?
Radiological investigations for urethral stricture are :- (1) Retrograde urethrography;  (2) Micturating cystourethrography;  (3) Endoscopy (urethroscopy);  (4) Sonographic urethrogram;  (5) High frequency USG.
1
Magnetic resonance imaging
Retrograde urethrogram
Micturating cystourethrogram
High frequency ultrasound
Radiology
null
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single
Blood is of fetal origin in:
Ans. C i.e. Vasa pre
3
Placenta pre
Abruptio placentae
Vasa pre
Placenta accreta
Gynaecology & Obstetrics
null
8580e4dd-929a-44eb-8974-d6609fce558f
single
Which is a protease inhibitor?
(C) Squanavir
3
Azothymidine
Zidovudine
Squanavir
Acyclovir
Pharmacology
Miscellaneous (Pharmacology)
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single
Meyers Kouwenaar syndrome is a synonym for -
Occult FilariasisThis term is applied to clinical conditions not directly due to lymphatic involvement, but to hypersensitivity reactions to filarial antigens. Here microfilariae are not seen in blood but may be present at the affected sites. The condition may be caused by Wuchereria, Brugia or by some animal filaria a...
3
Tropical pulmonary eosinophilia
Larva migrans
Occult filariasis
Cutaneous allergic reactions to Ascariasis
Microbiology
parasitology
418d76dd-c1f7-4902-a073-1732cae434ac
multi
How many antenatal visits covering the entire period of pregnancy are minimum required?
Minimum no. of Antenatal visits required in Pregnancy : 4 1st visit - within 12 weeks, preferably as soon as the pregnancy is suspected, for registration of pregnancy and first antenatal check-up. 2nd visit between 14 and 26 weeks POG. 3rd visit - between 28 and 34 weeks POG. 4th visit - between 36 weeks - Delivery Rec...
2
3
4
7
13
Social & Preventive Medicine
Obstetric Care in RCH: Visits, IFA, TT, MCH Indicators
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Which of the following anaemias is a risk factor for the development of gastric carcinoma ?
Ans. is 'a' i.e., Pernicious anaemia
1
Pernicious anaemia
Megaloblastic anaemia
Aplastic anaemia
Haemolytic anaemia
Surgery
null
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single
All of the following about LSD intoxication are true except -
Drug of choice for LSD intoxication is Diazepam. Neuroleptics (e.g. phenothiazines) may have psychomimetic effects and thus are not indicated in patients with LSD intoxication.
4
Panic
Confusion
Hypereflexia
Treatment is phenothiazines
Psychiatry
null
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multi
Standard Deviation (SD) formula
null
3
Highest X-lowest X/2
Σ(X-X)/n
Σ(X-X)2/n
Σ(X-X)2/n-1
Dental
null
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single
A patient has been diagnosed with achalasia. He refused surgery initially, preferring to try nonoperative therapy. He tried life-style modification, calcium channel blockers, botulin toxin injection, and endoscopic pneumatic dilatation. None of the treatments alleviated his symptoms. What are his surgical options?
A healthy patient with achalasia who has failed nonoperative management should be considered for surgical intervention. Pneumatic dilatation is first-line therapy. It causes disruption of the muscular layers of the LES. A balloon is placed endoscopically at the level of the LES. Fluoroscopically is used to visualize th...
3
Esophagectomy
Surgical esophagomyotomy proximal to the LES
Modified Heller myotomy and partial fundoplication
Repeat pneumatic dilation using pressures of loops
Surgery
Stomach & Duodenum
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multi
In which of the following condition elevated ACTH and coisol levels in comparison to a normal individual in the evening
Addison disease primary adrenal insufficiency due to disease that destroy the adrenal coex ref : harissons 21st ed
3
addison disease
normal person after giving dexamethasone
normal person after waking up in morning
Cushing's syndrome
Medicine
All India exam
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single
In renal failure diuretic phase occur on -
Oliguric (anuric) phase: Urine output decreases from renal tubule damage. 3. Diuretic phase: The kidneys try to heal and urine output increases, but tubule scarring and damage occur occurs in 14-20 days.. Recovery phase: Tubular edema resolves and renal function improves. Ref Harrison20th edition pg 288
4
11st day
3rd day
28-35 day
14-18 day
Medicine
Kidney
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single
Aspirin is contraindicated in a case who is on treatment with:
Warfarin
2
Prednisolone
Warfarin
Theophyline
Oral contraceptives
Pharmacology
null
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Which of the following is true about incidence?
INCIDENCE Incidence rate is defined as "the number of NEW cases occurring in a defined population during a specified period of time". It will be seen from the above definition that incidence rate refers a. only to new cases b. during a given period (usually one year) c. in a specified population or "population at risk"...
4
Used for chronic conditions
Measures old & new cases
More than prevalence
Not affected by duration
Social & Preventive Medicine
Epidemiology
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Shoest and narrowest pa of fallopian tube:
Pas of the fallopian tube Interstitial pa: shoest, internal diameter 1mm (narrowest) Isthmus:35 mm long, lumen diameter 2-3 mm Ampulla: 60-75 mm long, widest . Feilisation takes place here Infundibulum: where abdominal ostium opens into the peritoneal cavity
1
Interstitial
Isthmus
Ampulla
Infundibulum
Gynaecology & Obstetrics
Maternal Anatomy and Physiology
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multi
All of the following statement about Kawasaki's disease are true except
Kawasaki disease is a vasculitis that mostly involves the coronary vessels. It presents as an acute systemic disorder, usually affecting children under 5 years.Kawasaki's disease is an acute, febrile, multisystem disease of children. Some 80% of cases occur prior to the age of 5, with the peak incidence occurring at <=...
4
It is the most common immune mediated vasculitis in children
Coronary aery aneurysm is seen in 25% of patients
Intravenous imunoglobuIin is indicated only in patients with coronary aery aneurysm
All the above
Medicine
Immune system
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multi
Which of the following is least in protein quality ?
null
1
Gelatin
Lactalbumin
Albumin
Cashewnut protein
Social & Preventive Medicine
null
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single
Capsule of Cryptococcus in CSF is best seen by-
Negative staining with India ink or Nigrosine are used to stain the capsule of Cryptococcus neoformans in CSF or blood.
2
Gram stain
India ink preparation
Mucicarmine stain
Methenamine silver stain
Microbiology
Mycology
1775d277-8146-40ff-a234-6948edaa380f
single
True about Alpha1 antitrypsin deficiency is?
(255) All of the above REF: Robbin's 7th ed p. 913 Alpha 1 antitrypsin deficiency: Due to protease inhibitor deficiency Increased neutrophill elastase Neonatal cholestasis may occur, Hepatocellular carcinoma may also develop Pulmonary disease may occur in form of emphysema Gene located on chromosome 14
4
Deficiency of protease inhibitor
Autosomal recessive
May cause cholestatic jaundice
All of the above
Pediatrics
null
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multi
Which of the following structure is fixed during reimplantation of an amputated digit
.
1
Bone
Aery
Vein
Nerve
Surgery
Trauma
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single
All are methods of sterilization by dry heat except -
Dry heat : Flaming, incineration, hot air REF:Ananthanarayan & paniker's textbook of Microbiology 9th edition page no 78
4
Flaming
Incineration
Hot air oven
Autoclaving
Microbiology
general microbiology
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multi
Scabard trachea is seen in -
null
4
Thyroid cancer
Thyroiditis
Goitre
All the above
Surgery
null
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multi
NOT true about fungal Corneal ulcer
Fungal Corneal ulcer is painless.
1
Excruciating pain in the eye
Feathery margins
Large hypopyon, non sterile and non mobile
Multiple satellite like lesions
Ophthalmology
null
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multi
Zollinger Ellison syndrome is characterized by
Endocrine causes of duodenal ulcers can be Zollinger-Ellison syndrome, MEN syndrome, hyperparathyroidism.ZOLLINGER ELLISON SYNDROME is characterised by fulminant ulcer in stomach and duodenum and its recurrences in spite of adequate therapy .they are also characterised by non-beta cell islet tumours of pancreas Ref: SR...
4
Fulminating ulcer in stomach and duodenum
Recurrent ulceration despite adequate therapy
Non-beta islet cell tumors of the pancreas
All of the above
Surgery
G.I.T
69cea29b-f416-499e-a554-b9b74c57ca64
multi
Which of the following is the most likely cause of infants hyperbilirubinemia
Diseases or conditions that can cause jaundice include: Internal bleeding (hemorrhage) An infection in your baby&;s blood (sepsis) Other viral or bacterial infections. An incompatibility between the mother&;s blood and the baby&;s blood. A liver malfunction. An enzyme deficiency. Reference: GHAI Essential pediatrics, 8...
3
Biliary atresia
Breast milk jaundice
Breast feeding jaundice
ABO incompatibility
Pediatrics
Gastrointestinal tract
322f7eca-fe38-4648-8156-20ca3f92ae1f
single
The absence of intestinal motility in the normal small intestine is best described as
.
4
A migrating motor complex
An interdigeti ve state
Segmentation
Physiological ileus
Anatomy
All India exam
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multi
Which of the following is the most toxic compound of mercury?
Mercuric chloride or corrosive sublimate is the most toxic compound of mercury. Characteristic features of chronic mercury poisoning are danbury tremors, hatters shakes, concussio mercurialis, mercurial erethism, mercuriolentis and acrodynia. Ref: Essentials of Forensic Medicine and Toxicology by Dr K S Narayan Reddy 2...
1
Chloride
Oxide
Cyanide
Chromate
Forensic Medicine
null
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single
Cobblestone conjunctivitis is seen in -
Ans. is 'a' i.e., Spring Cattarrh * Cobble-stone or pavement stone appearance is seen in spring catarrh.Important signs of spring catarrhConjunctivalCornealPalpebralBulbar# Punctate epithelial keratitis# Ulcerative vernal keratitis: shallow transverse ulcer (Shield ulcer)# Vernal corneal plaques# Subepithelial scarring...
1
Spring Cattarrh
Phylctenular conjunctivitis
Inclusion conjunctivitis
Giany papillary conjunctivitis
Ophthalmology
Conjuctiva
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single
Commonest cause of sustained severe hypertension in children:
Ans. is 'c' Renal parenchymal disease Most common cause of persistent hypertension in child is - Intrinsic Renal DiseaseIntrinsic renal diseases causing persistent hypertensionChronic glomerulonephritis (Most common).Chronic pyelonephritisObstructive uropathyRenal tumours
3
Endocrine causes
Coarctation of aorta
Renal parenchyma disease
Pheochromocytoma
Medicine
Hypertension
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single
Blood group antigens chemically are made up of ?
Blood group antigens (ABO) Made up of glycoproteins. Expressed on the surface of RBCs and Platelets.
2
Carbohydrate
Glycoprotein
Phospholipids
Polysaccharide
Pathology
Platelet
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multi
A patient presents with fever, uicaria, itching and swelling followed by injection of Penicillin. It is due to
There are two clinical pictures that can result from penicillin allergy, namely acute (Type I) and sub-acute reactions (Type II) mediated by IgE and IgG antibodies respectively. The acute allergic reaction arises immediately or rapidly within minutes to an hour or two and includes sudden anaphylaxis with hypotension, b...
1
IgG Hypersensitivity
IgE Hypersensitivity
Delayed Hypersensitivity
Immune complex Hypersensitivity
Microbiology
Immunology
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single
Prophylactic antibiotics are most effective during
In the first 4 hours, after a breach in an epithelial surface and underlying connective tissues, there is delay in the mobilisation of host defences. This period is called 'decisive period' and during this period, bacterial colonisation and established infection can begin. It is logical that prophylactic antibiotics wi...
1
Decisive period
Infection period
Latent period
Golden period
Surgery
null
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single
All are radiological features of Mitral stenosis except –
Radiological signs of mitral stenosis Due to left atrial enlargement:- Straightening of left heart border, elevation of left main bronchus with the widening of the carina, double atrial shadow (Double density sign), posterior displacement of the esophagus on barium swallow, Prominent posterosuperior part of the cardia...
2
Straight left border of heart
Oligemia of upper lung fields
Pulmonary hemosiderosis
Lifting of left bronchus
Radiology
null
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multi
Shoest acting benzodiazepine is?
Ans. is 'c' i.e., Triazolam o Midazolam (slightly shoer acting than triazolam) and triazolam are shoest acting BZDs.
3
Flurazepam
Alprazolam
Triazolam
Diazepam
Pharmacology
null
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All are complication of tonsillitis EXCEPT:
Ans. (c) Malignant changeRef: DhingrcTs ENT 5th ed. / 272-273* Acute tonsillitis often affects school-going children, but it can also affect adults.Cause:* MCC: Group A Beta Hemolytic streptococcus* Acute infections of tonsil may involve these components and are thus classified as:# Acute catarrhal or superficial tonsi...
3
Otitis media
Abscess
Malignant change
Subacute Bacterial Endocarditis
ENT
Operative Surgery
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multi
All of the following statement about H (hormone replacement therapy) are true except
There is evidence that the progestogen pa of combined H can counteract the cancer-causing effects of the oestrogen pa, when it comes to endometrial cancer. But it depends on the type of combined H used. But it's impoant to remember that combined H causes the greatest increase in risk for breast cancer Ref Robbins 9/e p...
4
It increases the risk of coronary aery disease
It increases bone mineral density
It increases the risk of breast cancer
It increases the risk of endometrial cancer
Medicine
Genetics
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multi
Microscopic examination of a tumor shows 'Schiller Duval Bodies' which are characteristically seen in:
Yolk sac tumor (endodermal sinus tumor) is a germ cell tumor. The clinical presentation is similar to that of sarcoma botryoides, and the most common symptom is bloody vaginal discharge. Grossly, yolk sac tumor appears polypoid or sessile and often ulcerated. On microscopic examination, these tumors most commonly have ...
1
Endodermal sinus tumor
Choriocarcinoma
Granuloma cell tumor
Arrhenoblastoma
Gynaecology & Obstetrics
null
42142e44-d1ac-4a40-93bb-78dedb033c1c
multi
In which direction carcinoma maxilla spread to presented with pain refers to upper tooth
i.e. (Inferior): (221-Dhingra 5th)The direction of spread and extent of growth in Carcinoma of Maxillary Sinus* Medial spread - to the nasal cavity gives rise to nasal obstruction, discharge, and epistaxis.* Anterior spread - causes swelling of the cheek and later invasion of the facial skin* Inferior spread - causes e...
3
Medial
Lateral
Inferior
Posterior
Unknown
null
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Gallow's traction is used for fracture:
Ans is 'a' i.e. Shaft femur Gallows traction is used for treatment of fracture shaft femur, in infants and children < 2 yrs of age.Weight must not be more than 12 kgs.Both the fractured and the normal femur are placed in skin traction and the infant is suspended by these from a special frame. The buttocks should be lif...
1
Shaft femur
Neck femur
Shaft tibia
Tibial tuberosity
Orthopaedics
Management In Orthopedics
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"Gold standard" surgical procedure for prevention of aspiration is:
Aspiration is the passage of foreign material beyond the vocal cords: The larynx has 3 distinct functions - respiration, phonation and airway protection. Dysfunction of larynx can lead to aspiration. The primary goal of treatment of aspiration is to separate the upper digestive tract from the upper respiratory tract fo...
3
Thyroplasty
Tracheostomy
Tracheal division and permanent tracheostome
Feeding gastrostomy/jejunostomy
ENT
null
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A 75-year-old male patient who has recent hemiparesis came to the hospital for followup. On physical examination, stroking the plantar surface of foot produced a reflex extension of large toe and fanning of lateral toes. This is due to damage to one of the following structures
Upper motor neurons typically refer to coicospinal tract neurons that innervate spinal motor neurons, but they can also include brainstem neurons that control spinal motor neurons. Damage to these neurons initially causes muscles to become weak and flaccid but eventually leads to spasticity, hypeonia (increased resista...
4
Cerebellum
Basal ganglia
Lower motor neuron
Upper motor neuron
Physiology
Nervous system
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single
Mitochondrial membrance protein contain transpoer of
The electron transpo chain in the mitochondrial membrane has been separated in 4 (four) complexes or components as follows: Complex I: NADH-CoQ reductaseComplex II: Succinate-CoQ reductase Complex III: CoQ-cytochrome C reductase Complex IV: Cytochrome C oxidaseRef: MN Chatterjea Textbook of Medical Biochemistry, 8th Ed...
1
NADH
Acetyl COA
NADPH
ATP
Biochemistry
Respiratory chain
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In a chronic smoker which hemoptysis, he also gave a history of hypeension and obesity. Lab data showed raised ACTH levels, which are not suppressed by dexamethasone. The cause of Cushing's syndrome in the patient is -
- History of chronic smoking and hemoptysis along with raised ACTH levels not suppressible by dexamethasone points to ectopic ACTH producing small cell carcinoma of lung.
4
MEN1
Pituitary adenoma
Adrenal coical adenoma
Ectopic ACTH secreting tumor
Pathology
Adrenal Gland
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Forceps delivery is indicated in all of the following conditions, except
In brow presentation, the engaging diameter of head is mentoveical (14cm) . In this case vaginal delivery is impossible and elective caesarean section is usually performed.
4
Face presentation
Occipitoposterior
After warming head in breech
Brow presentation
Gynaecology & Obstetrics
null
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multi
All causes brain lesions except - rpt
Guardia lamblia causes giardiasis. the parasite attaches itself to the epithelial surface of duodenum and jejunum and causes disturbance of intestinal function leading to malabsoption of fat. The patient may complaints of persistent loosened of bowel and mild steatorrhoea. REF:Baveja textbook of microbiology 3rd editio...
1
Giardiasis
Tuberculosis
Cysticercosis
Bacteroids
Microbiology
mycology
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Heparin is a:
Ans. A. Glycosamino Glycan(Ref: Harper 31/e page 605)Heparin is a Glycosamino Glycan.Glycosamino Glycans are heteropolysacchrides.Disaccharide repeat unit is Glucosamine and Iduronic acid.Initially uronic acid present is Glucuronic acid, 5 epimerase convert 90% of GlcUA to IdUA.Heparin is found in the granules of mast ...
1
Glycosamino glycan
Polysaccharide
Proteoglycan
Carbohydrate
Biochemistry
Carbohydrates
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Most sensitive investigation for air embolism is –
Although transesophageal echocardiography (TEE) is the most sensitive method for venous air embolism (VAE) detection and is considered the "gold standard", it is costly and more invasive. When properly placed, a precordial Doppler is capable of identifying VAE at an air infusion rate as low as 0.015 ml/kg/ min and cons...
3
Decreased tidal volume of CO2
Decreased tidal volume of NO2
Doppler ultrasound
Central venous presure
Radiology
null
2e7b632e-6213-4aa4-a602-d8762978d758
single
Multiple painful ulcers with inguinal lymphadenopathy. Diagnosis is?
Ans. is 'b' i.e. Chancroid* Chancaroid characteristically present with multiple painful ulcers with no or soft induration with painful suppurative inguinal lymphadenopathy.* They have undermined, sloughed erythematous edges & bleed easily.Characteristics of various different types of genital ulcersi) Primary syphilis (...
2
Syphilis
Chancroid
LGV
Donovanosis
Skin
S.T.D.
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Copper is mainly transpoed by
Normally, dietary copper is more than body's requirement. Excess copper so absorbed through the stomach and duodenum is transpoed to the liver where it is incorporated into a2-globulin to form ceruloplasmin, which is excreted by the liver bile normally. Most of the plasma copper circulates as ceruloplasmin. Only minute...
1
Ceruloplasmin
Albumin
Haptoglobin
Globulin
Pathology
G.I.T
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Indication of Manchester operation in prolapse :
Ans. is b and c i.e. Women of < 35 yrs age; and Patient who wants child bearing function Fothergill's repair It is suitable for women under 40 years who are desirous of retaining their menstrual and reproductive function." In congenital elongation of cervix management is amputation of cervix which is just a pa of Fothe...
2
Nulliparous
Women of < 35 yrs age
Patient who wants child bearing function
Congenital elongation of cervix
Gynaecology & Obstetrics
null
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Mental retardation is a clinical feature of:
Ans. (d) PhenylketonuriaRef: Harrisons 20th ed. P 3015 - 16Phenylketonuria* MC metabolic disorder of amino acid* Seen due to deficiency of enzyme: Phenylalanine Hydroxylase* Increased phenylalanine in blood - metabolized to phenylketones - excreted in urine - hence the name Phenylketonuria (PKU).* MC organ damaged due ...
4
Alkaptonuria
Albinism
Hawkinsinuria
Phenylketonuria
Biochemistry
Proteins and Amino Acids
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Which of the following ducts are not associated with salivary glands
The accessory pancreatic duct is called the Duct of Santorini.The duct of submandibular gland is Whaon ductThe duct of the parotid gland is Stensen ductThe duct of sublingual gland drains by multiple small numerous small ducts all of which open into the floor of the mouth and are collectively termed as duct of RivinusR...
4
Whaon's duct
Stensen's duct
Ducts Of Rivinus
Ducts Of Santorini
Surgery
Head and neck
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single
Which of the following drugs is most likely to be absorbed from the stomach?
DICLOFENAC IS ABSORBED THROUGH STOMACH.Ref:KDT 6/e pg. 12
2
Morphine sulfate
Diclofenac sodium
Hyoscine hydrobromide
Quininedi hydrochloride
Pharmacology
All India exam
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single
In the presence of renal failure.............. should not be given -
Ans. is 'c' i.e., Spironolactone In renal failure loop diuretics (Furosemide, Bometanide. Torasemide) are DOC. Thiazides are ineffective in renal failure. Spironolactone can cause dangerous hyperkalemia if renal function is inadequate.
3
Furosemide
Bumetanide
Spironolactone
null
Pharmacology
null
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multi
A 38-year-old woman complains to her physician of chronic pelvic pain that is much worse during her menstrual periods. Pelvic examination demonstrates an enlarged uterus with multiple palpable masses. Ultrasound shows that a large number of ball-like masses up to 6 cm diameter are present in the uterus. Which of the fo...
Leiomyomas are benign ball-like masses that commonly form in the uterus. Cervical and uterine carcinomas tend to initially form a fairly superficial layer of cancer on the surface of the endocervix or uterine cavity, which may later become deeply infiltrative. Usually, no ball-like mass is produced. Leiomyosarcomas are...
3
Cervical adenocarcinoma
Cervical squamous cell carcinoma
Leiomyoma
Leiomyosarcoma
Gynaecology & Obstetrics
null
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multi
Most common route of spread of Hepatitis E is -
HEV is transmittef by fecal oral route REF:<\p> ANATHANARAYANAN MICROBIOLOGY NINTH EDITION PAGE.540
2
Sex
Feco-oral
Blood transfusion
IV injections
Microbiology
Virology
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single
Treatment of choice for HIV and TB along with Rifampicin is?
ANSWER: (C) RitonavirREF: Harrisons 17th ed chapter 182Ritonavir has a high affinity for several isoforms of cytochrome P450, and its use can result in large increases in the plasma concentrations of drugs metabolized by this pathway. Rifampicin is metabolized by the pathway and hence ritonavir used with rifampicin in ...
3
Saquinavir
Nevirapine
Ritonavir
Amprenavir
Medicine
Virology
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single
Investigation of choice for diagnosing macular edema:-
Optical Coherence Tomography Non-excisional "OPTICAL BIOPSY" Uses low coherence interferometry, employs michelson interferometer 830 nm infrared light, Super luminescent diode light source. Not very specific in hazy media and myopic discs
3
Biopsy
FA
Optical coherence tomography
ERG
Ophthalmology
Retina
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single
Kawasaki disease is associated with all of the following clinical features except -
null
3
Truncal rash
Posterior cervical lymphadenopathy
Thrombocytopenia
Conjunctivitis
Medicine
null
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multi
Cell injury occurs due to -
Ans. is 'a' i.e., ATP; 'b' i.e., is Cytosolic Ca'; 'c' i.e., Membrane damage; Cell injury o Cell injury results when cells are stressed so severly that they are no longer able to adapt i.e., when the limits of adaptive response to a stimulus are exceeded, cell injury occurs. o Cell injury is reversible up to a ceain po...
4
L ATP
T Cytosolic Ca'
Membrane damage
All
Pathology
null
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multi
Dyslipidemia associated with alcohol consumption-
Dyslipidemia is an abnormal amount of lipids (e.g. triglycerides, cholesterol and/or fat phospholipids) in the blood. In developed countries, most dyslipidemias are hyperlipidemias; that is, an elevation of lipids in the blood. This is often due to diet and lifestyle. Prolonged elevation of insulin levels can also lead...
2
Decreased HDL
Increased HDL
Decreased triglycerase
Decreased lipoprotein
Medicine
Miscellaneous
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single
Muscles are not involved in which glycogen storage disease-
- Muscle Glycogen Storage Diseases-TypeNameEnzyme DefectIIPompe's diseaseLysosomal a1, 4 & a1, 6 glucosidaseVMcArdle's diseaseMuscle phosphorylaseVII Muscle and erythrocyte phosphofructokinase 1
2
Type III
Type I
Type IV
Type II
Biochemistry
null
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single
A middle aged chronic alcoholic man complains of burning sensation in the mouth. On examination he has thickened, dry, smooth tongue with absence of the filliform papillae. MCV is 100. Which of the following should be first line of approach in the management of this patient?
The above given scenario is likely a case of Vitamin B12 deficiency hence estimation of Vitamin B12 levels should be the first step in management. Its deficiency may cause a bilateral peripheral neuropathy or degeneration (demyelination) of the cervical and thoracic posterior and lateral (pyramidal) tracts of the spina...
1
Estimation of Vitamin B12 levels
Brush biopsy
Sta Antifungal therapy
Incisional biopsy
Medicine
Anemia
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single
The following complications are likely to increase in a case of severe anemia during the pregnancy except :
Subinvolution
4
Pre-eclampsia
Intercurrent infection
Hea failure
Subinvolution
Gynaecology & Obstetrics
null
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multi
A child is brought to your clinic for a routine examination. She can put on a T-shirt but requires a bit of help dressing otherwise. She can copy a circle well but has difficulty in copying a square. Her speech is understandable and she knows four colors. She balances proudly on each foot for 2 seconds but is unable to...
Four- and five-year-old children should be able to copy a square and a cross; children younger than this age have difficulty with this task. By 4 years of age, their language should be fully understandable by the examiner. Children begin to be able to name four colors, define five words, and know three adjectives. A 4-...
1
1 year
2 years
3 years
4 years
Pediatrics
Growth, Development, and Behavior
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single
Which of the following rib is known as floating rib?
Ans. D 11Ref: Netter's Clinical Anatomy, 3rd ed. pg. 89* The 11th and 12th ribs are floating ribs as they are free at their ends.* The 8th, 9th and 10th ribs are false ribs as they are joined to form cartilage of rib immediately above.* The first 7 pair of ribs are true ribs.
4
8
9
10
11
Anatomy
Thorax
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single
The infarcted myocardium is replaced by scar tissue is in -
Ans. is 'c' i.e., 6 weeks
3
2 weeks
4 weeks
6 weeks
10 weeks
Pathology
null
e0b30754-98aa-47a0-8143-e4024ef96cba
single
Splenectomy is most successful in -
<p >Davidson&;s principles and practice of medicine 22nd edition. *in hereditary spherocytosis consideration is given to splenectomy ,which improves but does not normalised red cell survive.</p>
1
Hereditary spherocytosis
Chronic myeloid leukemia
Idiopathic thrombocy topenic purpura
Aplastic anaemia
Medicine
G.I.T
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single
The least common organ injured by blast injury is
Ans. (d) StomachRef: Love and Bailey 26th/e p. 430 * In blast injury ear, lung, heart are injured and to a lesser extent gastrointestinal tract occurs
4
Tympanic membrane
Alveoli of the lung
Skull
Stomach
Surgery
Trauma
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single
A 65-year old male is brought to the outpatient clinic with one year illness characterized by marked forgetfulness, visual hallucinations, suspiciousness, personality decline, poor self care and progressive deterioration in his condition. His Mini Mental Status Examination (MMSE) Score is 10. His most likely diagnosis ...
A i.e. Dementia
1
Dementia
Schizophrenia
Mania
Depression
Psychiatry
null
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multi
All of the following are definitive tests for developmental surveillance except:
Denver-II is a developmental screening test (not definitive test) which assesses child development in 4 domains Gross motor Fine motor adaptive Language and Personal Social behaviour Tests for the developmental quotient Definitive tests Screening Tests Bayley Scales of Infant and Todller development (Bayley-II) Stanfor...
3
Bayley-II
Stanford-Binet
Denver-II
Wechsler
Pediatrics
Growth and development
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multi
Decreased activity of type I 5'-monodeiodinase could lead to which physiologic effects:-
Type I 5'-monodeiodinase is the enzyme responsible for the peripheral conversion of thyroxine (T4) to triiodothyronine (T3), primarily in liver and kidney. This enzyme also participates in the breakdown of reverse T3 (rT3) by converting it to 3,3'-diiodothyro nine. Decreased activity of type I 5'-monodeiodinase will th...
2
Increased plasma triiodothyronine (T3)
Increased plasma reverse T3
Decreased plasma thyroxine T4
Increased TSH
Unknown
null
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single
Fracture of proximal forearm cast position is ?
Ans. is 'c' i.e., Supinated position
3
Pronated flexion
Neutral position
Supinated position
Position does not matter
Surgery
null
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single
Using a new technique, Hb was estimated in a blood sample. The test was repeated for 10 times. The reports were : 9.5, 9.2, 9.4, 9.6, 9.7, 9.9, 10.2, 10.3, 10.5, 12.1. Accurate value of Hb was estimated by standard tests to be 10.2. The new technique has -
Validity (Accuracy) The validity of a test is the extent to which it accurately measures which it purports to measure. In other words its the ability to show which individuals have the disease in question and which do not. Validity has two components - sensitivity & specificity. To be truly valid, a test should be hig...
2
High validity and high reliability
Low validity and low reliability
High validity and low reliability
Low validity and high reliability
Social & Preventive Medicine
null
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single
Indication of anti-D immunoglobulin is/are
Ans. is a, b and c i.e. Vaginal bleeding; ECV; Mid trimester aboion; and After amniocentesis As explained in the previous question : Anti D prophylaxis should be given after all types of aboions (threatened, medical. MTP) molar pregnancy, ectopic pregnancy, delivery (+manual removal of placenta), procedures performed a...
4
Vaginal bleeding
ECV
Mid trimester aboion and After amniocentesis both
All
Gynaecology & Obstetrics
null
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multi
All are true about respiratory viruses except
Ans. is 'b' i.e. Mumps causes septic meningitis Remember this,Bacterias cause septic meningitis whereas viruses cause aseptic meningitisRespiratory syncytial virus is the most important cause of (bronchiolitis) lower respiratory tract illness in infants and young children.Mumps and meningitis:-Central nervous system in...
2
RSV - common cause of bronchiolitis in infants
Mumps causes septic meningitis
SSPE is a late complication of measles
Para influenza attaches to cell by hemagglutinin
Microbiology
Virology
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multi
Sudomotor neuropathy in poisoning:-
Mnemonic Arsenic poisoning A - Anemia / Aldrich Mee's line / Arsenophagist (Tolerate upto 300mg ) R - Rain drop pigmentation / Reinsch test / Red velvety mucosa S - Sub endocardial hemorrhages / Sensory neuropathy E - Eruptions N - NAA I - Imbibition of arsenic ( Arsenic imbibed from surrounding soils after death ) / b...
1
Arsenic
Mercury
Lead
copper
Forensic Medicine
Toxicology - 3
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single
A man having multiple, painful, indurated, undermined, sloughed edged glans which occurred 5 days after exposures; most likely diagnosis is –
Step 1 Painful ulcer → Chancroid or HSV. Step 2 In the question, there is no information about step 2 → suppurative lymphadenopathy, U/L or B/L lymphadenopathy, presence or absence of vesicle. So go for step - 3. Step 3 Induration (+)nt → Chancroid Undermined sloughed edges → Chancroid
1
Chancroid
Primary chancre
Herpes genitalis
LGV
Dental
null
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single
Periapical granuloma is
A direct lift from Cohen. Bacteriological features of periapical granuloma: Majority of the studies have been based upon bacteriological cultures taken after the extraction of tooth Pre extraction cultures have been made in a few instances through the root canal or the alveolar plate and these have been relatively fre...
4
Anaerobic infection
Aerobic infection
Mixed infection
Sterile
Pathology
null
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single
Antipsychotic drug with least extrapyramidal effects is
null
1
Clozapine
Risperidone
Thioridazine
Chlorpromazine
Psychiatry
null
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single
A 15 year old female patient presents with pain in the calf muscles on exercise. Routine investigation reveals burgundy-colored urine (sample obtained after exercise). Histopathology of mucle shows deposits of glycogen in an excess amount. Which of the following treatment modality should not be followed in this patient...
Patient is suffering from type V Glycogen Storage Disease  (McArdle Disease). Treatment: Avoidance of strenuous exercise.  Glucose or sucrose given before exercise or injection of glucagon can markedly improve tolerance in these patients.  Vitamin B6 supplementation reduces exercise intolerance and muscle cramps.  No...
4
Avoidance of strenuous exercise
Glucose or sucrose given before exercise or injection of glucagon can markedly improve tolerance in these patients
Vitamin B6 supplementation
Specific enzyme replacement therapy (ERT) with recombinant human acid α-glucosidase
Biochemistry
null
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single
The radiographic appearance of Botryoid odontogenic cyst is
An unusual form of cyst called botryoid odontogenic cyst, manifests radiographically with a multilocular pattern, is simply a polycystic variant of the lateral periodontal cyst developing through cystic transformation of multiple islands of dental lamina rests. The  botryoid odontogenic cyst appears similar, except tha...
2
Apple green appearance
Grape bunch appearance
Lemon peel appearance
Orange peel appearance
Radiology
null
17bde1d1-8aad-47c0-8a91-2de7f03bea48
single
True about Hirschsprung’s disease is
Hirschsprung’s disease presents with non passage of stools in infants. Involved segment is not dilated Target sign is seen in intusussuption.
2
Involved segment of intestine is dilated
Non passage of meconium
Target sign
All of the above
Surgery
null
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multi
Neonatal moality is calculated as -
Neonatal moality rate is number of deaths of children <28 days per 1000 live bih. REF. PARK'S TEXTBOOK OF PREVENTIVE AND SOCIAL MEDICAL 21ST EDITION. PAGE NO - 521
1
Number of deaths of children <28 days per 1000 live bih
Number of deaths of children <28 days per 1000 still bih
Number of deaths of children <28 days per 1000 total bih
null
Social & Preventive Medicine
obstetrics,pediatrics and geriatrics
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multi
A patient needs antibiotic treatment for aificial valve, culture-positive infective enterococcal endocarditis. His medical history includes severe anaphylactic reaction to penicillin G during the past year. The best approach would be treatment with:
* Severe allergy to penicillins rule out the use of amoxicillin and cefazolin. * Vancomycin is highly effective against MRSA and enterococcal infections. * Drugs for VRSA and VRE (Vancomycin Resistant Enterococcus faecalis) include linezolid and daptomycin.
4
Amoxicillin-clavulanic acid
Aztreonam
Cefazolin plus gentamicin
Vancomycin
Pharmacology
Cell Wall Synthesis Inhibitors
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single
Each hemoglobin molecule contains how many globin?
Ans. is 'a' i.e., 1 Hemoglobin is the most impoant red cell constituent. The hemoglobin molecule is an assembly of four globular protein. Each subunit is composed of a protein (polypeptide) pa, i.e., globin and a nonprotein pa i.e., heme, i.e., Each hemoglobin molecule contains four heme units and two pairs of similar ...
1
1
2
3
4
Physiology
null
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single
Closing capacity of lung is related to
The closing capacity (CC) is the volume in the lungs at which its smallest airways, the respiratory bronchioles, collapse. It is defined mathematically as the sum of the closing volume and the residual volume. The alveoli lack suppoing cailage and so depend on other factors to keep them open Ref: guyton and hall textbo...
2
Small sized bronchioles without cailage in nondependent poion of lung
Small sized bronchioles without cailage in dependant poion of lung
Medium sized bronchioles without cailage in nondependent poion of lung
Medium sized bronchioles without cailage in dependent poion of lung
Physiology
Respiratory system
80afb734-9ad6-4794-87cc-55fec5fe5b94
multi
Duration of second stage of labor depends upon -
Ans. is 'c' i.e., Parity o The duration of the normal second stage is usually very much shorter than the normal first staee of labour.o As with the first stage the duration of the second stage will mainly depend on whether it is the first labour or the woman has previously given birth to a viable infant i. e. it depend...
3
Size of fetus
Mother's build
Parity
Lie of fetus
Gynaecology & Obstetrics
Second Stage of Labor
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single
Mongolian spots are seen most commonly over?
Ans. D. Presacral region. (Ref. Nelson Paediatrics 19th/Fig. 639-2).Mongolian spots, which are blue or slate-gray macular lesions, have variably defined margins; they occur most commonly in the presacral area but may be found over the posterior thighs, legs, back, and shoulders. They may be solitary or numerous and oft...
4
Shoulders
Occipital area
Mandibular area
Presacral region
Pediatrics
New Born Infants
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single
All of the following are true about this brain tumor except:
Meningioma (showing dural tail) Mostly occur along the superior sagittal sinus Most common intracranial, extra-axial dural-based neoplasm Associated with spasticity & lower limb weakness, sensory deficit and sphincter dysfunction of bladder Calcification is seen in 20-25% cases Simpson grading system is used for mening...
3
Most common intracranial, extra-axial dural-based neoplasm
Associated with spasticity & lower limb weakness, sensory deficit and sphincter dysfunction of bladder
Calcification is seen in 60-65% cases
Simpson grading system is used for resection
Surgery
CNS Tumors
befd2b1c-0a84-4695-a1a6-da69674d0649
multi
Inulin clearance is equal to
Inulin clearance is equal to about 125ml/min, which is the GFR.
3
55 ml/min
625 ml/min
125 ml/min
40 ml/min
Physiology
null
384491e5-d846-44a4-bc64-c14a5b345396
single
Basic pathology in rickets-
Ans. is 'b' i.e., Defect in mineralizationo To know the pathophysiology of rickets, one should know the structure of bone.o Bone consists of ?1) Protein matrix i.e. osteoid ----> also known as unmineralized bone.2) Mineral phase. principally composed of calcium and phosphate, mostly in the form of hydroxyapatite.o In r...
2
Defective bone matrix formation
Defect in mineralization
Defect in osteoid formation
All of the above
Pediatrics
null
626073aa-d879-4c9f-b526-ff8fa5df0b6f
multi
Which of the following is a mucolytic
Ambroxol & Bromhexine make the mucus less viscid & act as mucolytics.
4
Lignocaine
Aprepitant
Codeine
Ambroxol
Pharmacology
null
11d32642-8413-45e2-928e-d867e8d16f06
single
Which is not done in Septoplasty -
Anaesthetic consideration for intranasal surgeries Intranasal operations are septoplasty, polypectomy, rhinoplasty and FESS. Either a laryngeal mask or a cuffed endotracheal tube may be used with a throat pack, depending on the anaesthetist's confidence, the surgeon, the amount of blood loss and the duration of surger...
4
Elective hypotension
Throat pack
Nasal preparation with 10% cocaine
null
ENT
null
409f5fc6-ef56-4102-98a8-1560c99fcfe7
multi
Treatment of a large hydrocele in an infant:
Ans: c (Herniotomy)Ref: Bailey & Love, 24th ed, p. 1408 & 23rd ed, p. 1275
3
Repeated aspirations
Ligation of sac at the opening of inguinal canal
Herniotomy
Eversion of sac
Surgery
Testis & Scrotum
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single
The following statements are true with reference to Mycoplasma except -
null
2
They are the smallest prokaryotic organisms that can grow in cell free culture media
They are obligate intracellular organisms
They lack a cell wall
They are resistant to Beta-lactam drugs
Microbiology
null
13e56857-cd86-45dd-a107-96a685e9174d
multi