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46 year old female presented to OPD with complaints of breathlessness, purulent copious cough for 6 weeks. She lost 6 kg in 1.5 months. She was put on Clarithromycin and prednisolone for 2 weeks but there was no improvement in her condition . Chest Xray demonstrated persistent consolidation in the left lower lobe. What...
From the h/o purulent productive cough , loss of weight , and imaging study demonstrating consolidation in lung , adenocarcinoma in situ is a possibility and should be actively excluded by obtaining histology. Adenocarcinoma- seen in females & non smokers On CT scan , AIS is a nonsolid nodule On h/p, AIS shows lepidic ...
1
Adenocarcinoma in situ
Atypical pneumonia
Mesothelioma
Organising pneumonia
Medicine
Miscellaneous Questions
76670103-a2a9-4a03-809b-4d177225c5ca
single
A dairy farmer presented to the dermatology OPD with an ulcer with central black eschar over the forearm .Which of the following media will be used as selective medium for the growth of responsible organism?
Based on the profession of the person and clinical description of the lesionits most likely cutaneous anthrax (the most common form of Anthrax) and a selective medium used for it is PLET(polymyxin-lysozyme-EDTA-thallous acetate) medium. Neisseria meningitidis Thayer main medium B.pseudomallei Ashdown medium Brucella Ca...
1
PLET medium
Ashdown medium
Casteneda medium
Thayer main medium
Microbiology
Bacteriology
7c40c1c5-e7e2-4d2c-864a-4b9791412818
single
Cold agglutinins are seen in?
Ans is 'a' i.e. Influenza Cold agglutinin hemolytic anemiao This form of hemolytic anemia is caused by cold agglutinin IgM antibodies. Antibodies react with RBC at 0deg to 4degC. Both intravascular and extravascular hemolysis may occuro Causes of cold agglutinin immunohemolytic anemiaMycoplasma infection, IMN, CMV, Inf...
1
Influenza
PAN
Multiple myeloma
SLE
Unknown
null
b0c75adc-6df7-4f62-8da4-5e8c2321ab76
single
Cellular and flagellar movement is carried out by all of the following except
Intermediate filament is 8 to 14 nm in diameter and is made up of various subunits. Some of these filaments connect the nuclear membrane to the cell membrane. They form a flexible scaffolding for the cell and help it resist external pressure. In their absence, cells rupture more easily, and when they are abnormal in hu...
1
Intermediate filaments
Actin
Tubulin
Myosin
Physiology
General physiology
6c6343a6-49d6-4335-b55e-d48d53009bed
multi
The drug which can be considered as an alternative for splenectomy in severe autoimmune hemolytic anemia is:
Rituximab is effective in more than 80% of patients with severe autoimmune hemolytic anemia not responding to steroids. Ref: Harrison's principles of internal medicine, 18th edition ; Page :882.
3
Adalimubab
Eculizumab
Rituximab
IV immunoglobulin
Medicine
null
258634fd-57ce-43eb-8684-6e36abdbb2e2
single
Rate limiting enzyme in bile acid synthesis ?
Ans. is 'c' i.e., 7a-hydroxylase About half of the cholesterol in the body is ultimately metabolized to bile acids. The primary bile acids are synthesized from cholesterol in liver. These are cholic acid and chenodeoxycholic acid. Rate limiting enzyme in primary bile acids synthesis is 7a - hydroxylase (cholesterol 7a ...
3
Desmolase
21 a-hydroxylase
7a-hydroxylase
12a-hydroxylase
Biochemistry
null
1cedb5a8-51b0-49d4-b36a-51b6738f6261
single
Risk of endocarditis among the following is highest in
Risk of endocarditis - Ventricular septal defect > patent ductus arteriosus > Atrial septal defect.
1
Ventricular septal defect
Patent ductus arteriosus
Atrial septal defect
Mitral stenosis
Pediatrics
null
b827d3fe-58c7-41e0-8d00-0bd5e374352f
single
The type of hemoglobin that has least affinity for 1, 3- Diphosphoglycerate (2,3-DPG) or (2, 3-BPG) is
Fetal hemoglobin has least affinity for 13diphosphoglycerate Ref: guyton and hall textbook of medical physiology 12 edition page number: 312,313,314
2
Hg A
Hg F
HB
Hg A2
Physiology
Respiratory system
39e50e82-7173-4969-bb63-4838208c765b
single
All are autosomal recessive except: (Repeat)
Ans: D (Huntington's chorea) Ref: Harrison's Principles of Internal Medicine, 18th edition, page 3148Explanation: (See the following table)
4
Haemochromatosis
Sickle cell anaemia
Friederich ataxia
B. Huntington's chorea
Medicine
Genetics
b0e39ab4-aa7a-4f88-846c-b18dc9474b80
multi
Nagayama spots is seen in
Ulcer at Uvulopalatoglossal  junction is called Nagayama spots caused by Roseola infantum.
4
Measles
Mumps
Rubella
Roseola infantum
Pediatrics
null
a8d42114-bf9d-46e7-bf2b-15c6ae11af19
single
The scientist who discovered the transmission of malaria by anopheline mosquito -
Discovery Malarial parasite-Charles Laveran Life cycle-A.Bignami,B.Grassi, G.Bastianelli Anopheles species are vectors-Ronald Ross Culture malarial parasite-Trager and Jensen (refer pgno:54 baveja 3 rd edition )
3
Laveran
Paul muller
Ronal Ross
Pampana
Microbiology
parasitology
c4ee82c1-c51d-4ad6-8d38-8b1d5fcd7464
single
A 40 year old patient is suffering from carotid body tumor. Which of the following is the best choice of treatment for him-
Carotid Body Tumor (Chemodectoma) Arises from chemoreceptor cells on the medial side of carotid bulb Histologically it is a non-chromaffin paraganglioma Usually benign, unifocal and non-heriditary, schamblin classification is used for carotid body tumor. Associated with pheochromocytoma Higher incidence in areas where ...
1
Excision of tumor
Radiotherapy
Chemotherapy
Carotid aery ligation
Anatomy
Head and neck
536b6cc0-42ea-43b2-abe3-5399d150627e
single
Doughnut granuloma is a finding of :-
A fibrin ring granuloma also known as doughnut granuloma is a histopathological finding that is characteristic of Q fever. On H & E stain, fibrin ring granuloma consists of a central lipid vacuole surrounded by a dense red fibrin ring and epithelioid macrophages Fibrin ring granulomas may also be seen in Hodgkin's dise...
2
RMSF
Q fever
Lyme disease
Ehrlichiosis
Microbiology
Systemic Bacteriology (Haemophilus, Yersinia, Spirochaetes, Ricketssia, Chlamydia, Mycoplasma and Miscellaneous Bacteria)
da6327a2-d9fe-4492-ad82-c040801789db
single
Which type of collagen fibers demonstrates "Chicken wire" configuration?
null
4
Type I
Type II
Type III
Type IV
Dental
null
a1ed0ce2-4dab-41cf-a8b5-41e368549b28
single
Psammoma bodies are seen in the following except ?
Ans. is 'b' i.e., Mucinous cysadenoma of ovary
2
Serous cystadenoma of ovary
Mucinous cysadenoma of ovary
Meningioma
Papillary carcinoma of thyroid
Pathology
null
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multi
Which of the following is not a component of superficial perineal pouch?
Ans. a. Sphincter urethrae (Ref: BDC 5/e vol-Il p361-64: Keith Moore 6/e p404-6; Gray's 40/e p1093-97)Sphincter urethrae is not a component of superficial perineal pouch."Root, crura and bulb of penis (corpus spongiosa and corpora cavernosa), bulbospongiosus muscle, ducts of bulbourethral gland, and posterior scrotal n...
1
Sphincter urethrae
Buibospongiosus
Posterior scrotal nerves
Duct of bulbourethral glands
Anatomy
Pelvis
db5fef4c-5673-4572-a1a0-e8ba1eb2a1b6
single
The most common cause of renal scarring in a 3 years old child is:
c. Vesicoureteral reflux induced pyelonephritis(Ref: Nelson's 20/e p 2562-2567Ghai 8/e p 485-486)Most common cause of renal scarring in a child is VUR-induced pyelonephritis.
3
Trauma
Tuberculosis
Vesicoureteral reflux induced pyelonephritis
Interstitial nephritis
Pediatrics
Kidney
229d0293-4026-41a2-b998-6cc9e8fd2185
single
Loeys-Dietz Syndrome is characterized by all of the following Except
Loeys-Dietz syndrome is phenotypically distinct from Marfan syndrome. It is characterized as an aneurysmal syndrome with widespread systemic involvement. Loeys-Dietz syndrome is an aggressive, autosomal dominant condition that is distinguished by the triad of aerial touosity and aneurysms, hypeelorism (widely spaced ey...
4
Aerial aneurysms
Hypeelorism
Bifid uvula
Mutations in the gene encoding filamin A (FLNA)
Medicine
C.V.S
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multi
All of the following therapies may be required in a 1 hour old infant with severe bih asphyxia except ____________
Treatment with dexamethasone in neonatal asphyxia initiates hypoxic ischaemic brain injury. Reference: GHAI Essential pediatrics, 8th edition
2
Glucose
Dexamethasone
Calcium gluconate
Normal saline
Pediatrics
New born infants
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multi
In DNA transfer the vectors used to inse smallest to largest DNA is
Most general plasmids may be used to clone DNA inse of up to 15 kb in size. Phages can readily accept DNA fragments 10 to 20 kb longCosmids can carry inses of chimeric DNA that are 35 to 50 kb long.Ref: Harper 30th edition pg: 455
2
Cosmids, Plasmids, Bacteriophage
Plasmids, Bacteriophage, Cosmids
Bacteriophage, Cosmids, Plasmids
Cosmids, Bacteriophage, Plasmids
Biochemistry
Structure and function of protein
59dbcd33-5bca-43c6-88f7-e3d53b435918
multi
Casoni Test is used to detect infection caused by which of the following organism?
Casoni's test is used in the diagnosis of Hydatid disease, caused by Echinococcus granulosus. In this test, 0.2ml of sterile hydatid fluid is injected intradermally into one arm. This test is considered to be positive if large wheal, 5 cm in diameter with multiple pseudopodia develop in 30 minutes. Other test used to d...
3
Syphilis
Toxocariasis
Echinococcus granulosus
Trichinellosis
Microbiology
null
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A cystic, transilluminant, painless scrotal swelling presented with testes separately palpable. The procedure to be done is
(A) Lords' procedure # Hydrocele is a collection of serous fluid that results from a defect or irritation in the tunica vaginalis of the scrotum. Hydroceles also may arise in the spermatic cord or the canal of Nuck.> Structurally, hydroceles are classified into 3 principal types.> In a communicating (congenital) hydroc...
1
Lords' procedure
Hunters' procedure
Gibbons' procedure
Ombredanne's procedure
Surgery
Miscellaneous
5c0d9ea8-b9b0-4533-9251-c29e73f4abc4
single
Which of the following veins is found in relation to the paraduodenal fossa?
The paraduodenal recess / fossa is present in about 20% of subjects. The inferior mesenteric vein lies in the free edge of the peritonial fold. Ref: Last's Anatomy, 11th Edition, Page 263 ; Cunningham's Textbook of Anatomy By Daniel John Cunningham, Page 1186; Meyers' Dynamic Radiology of the Abdomen: Normal and Pathol...
1
Inferior mesentric vein
Middle colic vein
Left colic vein
Splenic vein
Anatomy
null
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single
Which form of plague can spread from person to person?
In cases of bubonic plague, bacilli are locked up within the lymph nodes and are not infective. Pneumonic plague is highly infectious and spreads from person to person through droplet method. Ref: Park 21st edition: page 270.
2
Bubonic plague
Pneumonic plague
Septicaemic plague
None of the above.
Social & Preventive Medicine
null
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multi
In congenital diaphragmatic hernia all are seen except-
null
2
Common on left side
Abdominal distension
Can be detected antenatally
Heart beat shifted to right
Surgery
null
89bb34bb-0bf7-463a-ae0b-ea383c615228
multi
Dietery factors associated with colon carcinoma -a) High fiberb) Low fiberc) Smoked fishd) High fat intakee) Japanese are common to develop Ca colon
A high incidence of colorectal cancer is seen in economically prosperous, upper socioeconomic class. This observation led to attention on environmental factors, particularly diet in the etiology of colon cancer. Dietary factors associated with colon cancers are: Animal fat diet high in animal fats such as found in r...
4
abc
ade
ace
bde
Surgery
null
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single
Potassium Iodide given for cough acts as
Potassium Iodide is an expectorant that increases bronchial secretion either directly by irritating bronchial glands or indirectly by causing gastric irritation.
2
Central antitussive
Expectorant
Peripheral antitussive
Mucolytic
Pharmacology
null
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single
A male was brought unconscious to the hospital with external injuries. CT brain showed no midline shift, but basal cisterns were compressed with multiple small hemorrhages. What is the diagnosis –
Diffuse axonal injury (DAI) and Cerebral contusions are the most common primary brain injuries in non-penetrating trauma to head, comprising almost 95% of primary injuries. Diffuse axonal injury (the most common primary brain injury), there is a shearing injury of axons most commonly at the cortico-medullary junction,...
4
Cortical contusion
Cerebral laceration
Multiple infarcts
Diffuse axonal injuries
Radiology
null
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multi
Which of the changes occur in bone growth ?
Ans. is 'd' i.e., Increased osteocalcin Bone growth o Osteoblasts are the cell in bone which form the bone.o Osteoclasts cause resorption of bone.o Osteoblasts and osteoclasts act in coordination and are considered the functional unit of bone know as the basic multicellular unit (BMU).o The processes of bone formation ...
4
Increased acid phosphatase
Increased urinary calcium
Increased bone nucleotidase
Increased osteocalcin
Pathology
null
06e76c96-932d-4eb5-a493-43a2869422e6
single
S 100 is a marker of ?
Ans. is 'd' i.e., All of the above o S 100 is normally present in cells derived from the neural crest (Schwann cells, melanocytes, and glial cells), chondrocytes, adipocytes, myoepithelial cells, macrophages, Langerhans cells, dendritic cells, and keratinocytes. It may be present in some breast epithelial cells. o S 10...
4
Melanoma
Schwannoma
Histiocytoma
All of the above
Pathology
null
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multi
A copolymer which has a direct chain of one type and branches of other type is called a
null
1
Graft copolymer
Block copolymer
Random polymerisation
Branched chain polymerization
Dental
null
54c1c34e-e850-4306-a4fc-c43b316fac6b
multi
Hepatitis B can transmitted through all of the following routes EXCEPT:
However universal precaution is not needed for breast milk (no occupational hazard), Human breast milk has been implicated in perinatal transmission of HIV, and HBsAg has been found in the milk of mothers infected with HBV (REF: JAMA 1988; 259:1353-6. Lifson AR, Bond WW, Petersen NJ, Gravelle CR, Favero MS. Hepatitis B...
3
Milk
Semen
Stool
Blood
Medicine
null
597a8418-18bb-4b2a-983a-effadd359927
multi
A patient with low-grade fever and weight loss has a poor excursion on the right side of the chest with decreased fremitus, dullness to percussion, and decreased breath sound all on the right. The trachea has deted to the left. The most likely diagnosis is
The diagnosis in this patient is suggested by the physical exam findings.The findings of poor excursion, the flatness of percussion, and decreased fremitus on the right side are all consistent with a right-sided pleural effusion.A large right-sided effusion may shift the trachea to the left. A pneumothorax should resul...
2
Pneumothorax
Pleural effusion
Consolidated pneumonia
Atelectasis
Microbiology
All India exam
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multi
Referred pain from ureteric colic is felt in the groin due to involvement of the following nerve:
Ans. (c) Ilio Inguinal nerve > Ilio hypogastric nerve* Ilio inguinal nerve supplies the medial side of thigh and hence pain radiation more chances from Ilio Inguinal nerve, (loin to groin)* Loin to testicles - Genital Br of GF nerve
3
Subcostal
Iliohypogastric
Ilioinguinal
Genitofemoral
Surgery
Kidney & Ureturs
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single
Increased incidence of reaction to L.A will occur by
null
1
Rapid rate of injection
Using an aspirating technique
Addition of vaso constrictor to the solution
Premedication with barbiturate
Surgery
null
f59c5b87-f89b-4a6a-b5d2-52f51e246792
single
Elements of primary health care include all of the following except -
Elements of primary health care education concerning prevailing health problems and the method of preventing and controlling them Promotion of food supply and proper nutrition An adequate supply of safe water and basic sanitation Maternal and child health care including family planning Immunization against major infect...
3
Adequate supply of safe water and basic sanitation
Providing essential drugs
Sound referral system
Health education
Social & Preventive Medicine
Health care of community & international health
5a501c7c-ca99-4fb7-9778-2da6199bdc64
multi
Hypopigmented lesions are seen in -
In melasma brown / grey brown macular pigmentation with well defined scalloped margins. Pigmentation darkens on sun exposure. Lichen planus pigmentosus produces hyperpigmented slate grey to bluish black coloured macules. melasma is a accquired hyperpigmentary disorder characterised by brownish black or bluish macules o...
3
Melasma
Lichen planus pigmentosus
Pityriasis alba
Uicaria pigmentosa
Dental
Skin lesions and disorders of pigmentation
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single
Most essential medicines are formulated as
Essential medicines are those that satisfy the priority health care needs of the population. Criteria for selection of essential medicines Essential medicines are selected with due regard to disease prevalence and public health relevance, evidence of clinical efficacy and safety, and comparative costs and cost-effectiv...
2
No compound
Single compound
Multiple compound
Fixed dose combination
Anatomy
General anatomy
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single
Circulatory shock is an example of
null
2
Hypoxic Hypoxia
Stagnant Hypoxia
Histotoxic Hypoxia
Anemic Hypoxia
Physiology
null
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single
All of the following are contraindications to tocolysis except:
Ans. is d, i.e. Placenta previaRef. Dutta Obs. 7/e, p 319Contraindications to tocolysis* Chorioamnionitis* Advanced labor* Abruption* Congenital anomalies not compatible with life* Preeclampsia/eclampsia* Fetal distress* IUFD* Pregnancy >34 weeksAs far as placenta previa is concerned tocolysis is not contraindicated Ma...
4
Chorioamnionitis
Fetal distress
Anencephaly
Placenta previa
Gynaecology & Obstetrics
Normal Labour
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multi
A probable etiology of gingivosis is?
null
2
High progesterone levels
Deficiency of estrogen and testosterone
Pregnancy
Aldosterone deficiency
Dental
null
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single
Bipolar disorder is child is detected by
(D) All of the above # Genetic Hypothesis: The life-time risk for the first degree relatives of bipolar mood disorder patients is 25%, and of recurrent depressive disorder patients is 20%.> The life-time risk for the children of one parent with mood disorder is 27% and of both parents with mood disorder is 74%.> The co...
4
Family history of bipolar disorder
Delayed sleep onset
Ventricular dilatation
All of the above
Medicine
Miscellaneous
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multi
The caudate lobe of liver corresponds to which segment of Counaud's classification :
Caudate lobe is segment I Quadrate lobe is segment IVa The caudate lobe (segment I) is the dorsal portion of the liver and embraces the IVC. It lies posterior to the left portal triad inferiorly and left and middle hepatic vein superiorly. Caudate lobe is unique in sense that it receives blood supply from both the ri...
1
Segment I
Segment II
Segment III
Segment IV
Surgery
null
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single
During evaluation of the cause of varicocele in a 36-year-old man, attention is directed to the method of drainage of the left testicular vein, which usually enters which of the following?
The left testicular vein empties into the left renal vein, and the right testicular vein empties into the IVC. Partial occlusion of the right renal vein is an uncommon cause of varicocele and may signify an associated retroperitoneal malignancy.
2
Left adrenal vein
Left renal vein
Left inferior mesenteric vein
Inferior vena cava (IVC)
Surgery
Urethra & Penis
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multi
All of the following are adverse effects of thioamide group of antithyroid drugs except?
Thioamide group of drugs includes carbimazole,methimazole and Propylthiouracil. Agranulocytosis and aplastic anemia are rare adverse effect seen with this group of drugs.Propylthiouracil carries the risk of hepatotoxicity.
4
Agranulocytosis
Aplastic anemia
Liver toxicity
Lung fibrosis
Pharmacology
null
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multi
Which of the following is the mechanism of action of local anaesthetics?
"Local anaesthetics block the conduction of action potential by blocking voltage gated Na+ channels". Ref: Medical Pharmacology at a Glance By Michael J. Neal 4/e, Page 15 ; Instant Pharmacology By Kourosh Saeb Parsy, Ravi G, Assomul, Fakkar J. Khan, Kasra Saeb Parsy, Eamonn Kelly; Page 123
1
Block Na+ channel
Block K+ channel
Open Na+ channel
Block Ca+ channel
Anaesthesia
null
1ebc63bd-ddd4-4c29-9bf1-2056f010df68
single
Definition of hypertrophy is?
Ans. is 'b' i.e., Increase in size of cells Hypertrophy* Hypertrophy refers to an increase in the size of cells without an increase in the number, resulting in an increase in the size of tissue. Hypertrophy involves cell enlargement without cell division. So, the hypertrophied organ has just larger cells, but no new ce...
2
Increased protein content of the cells
Increase in size of cells
Increase in number of cells
None of the above
Unknown
null
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multi
Acute lung injury is caused by all of the following except -
Ans. is 'None' o ARDS is an acute diffuse alveolar injury that is caused by variety of aetiological factors. o Patients with ARDS are often seriously ill with some other disease and features ofARDS are superimposed on them. Causes ofARDS Direct lung injury o Pneumonia o Aspiration of gastric contents o Inhalational inj...
4
Aspiration
Toxic gas inhalation
Cardiopulmonary bypass with hea lung machine
null
Pathology
null
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multi
Spuriously high BP is seen in all except
The auscultatory gap may give a falsely low recording of systolic BP, not spuriously high BP. In older patients with wide pulse pressure and in some hypeensive patients, the korotkoff sounds may become inaudible between SBP and DBP, reappear as cuff deflation continues, this is known as auscultatory gap. Small cuff siz...
1
Ausculatory BP
Small cuff
Thick calcified vessel
Obesity
Physiology
Cardiovascular system
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multi
Heat stiffening in muscles occurs above temperature (degC) -
Heat stiffening of muscles occur in temperature above 60 degree celsius due to denaturation and coagulation of muscle proteins. It simulates rigor mois. This remains till decomposition stas and there was no rigor mois. Dr. Narayana Reddys Synopsis of Forensic Medicine & Toxicology 27 th edition pg. 80.
4
30
40
50
60
Forensic Medicine
Death and postmortem changes
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multi
The treatment of choice for squamous cell anal cancer?
Squamous cell anal cancer is rare but associated with Human papilloma virus infection (HPV), Anal intra-epithelial neoplasia (AIN) and immunosuppression. The current treatment of anal canal carcinoma is chemoradiotherapy (combined modality therapy). Chemotherapy include a combination of 5-FU with mitomycin C or Cisplat...
2
Laser fulgaration
Chemoradiotherapy
Abdominoperennial resection
Platinum-based chemotherapy
Surgery
null
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single
Vital bleaching temperature
The temperature safely tolerated by pulp is 115-140 °F
2
100-115℉
115-140℉
140-160℉
160℉ - till patient tolerates
Dental
null
04d1777a-45b3-4bab-a3bb-a11c6a2ec6dd
single
True about battered baby syndrome:
Ans. d. AllThe clinical manifestations of Battered baby syndromes are: bruises, scars, internal organ damage, and fractures in various stages of healing.CLINICAL FINDINGSBruisesIt is most commonly seen.Accidental--It is thin, leading surfaces overlying bone edges (e.g., shins)Non-accidental-- Back of hands, Buttock reg...
4
Posterior rib fracture may be seen in X-ray
Injury at the side of metaphysic is specific
Epiphyseal injury is common
All
Pediatrics
Miscellaneous
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multi
Kwashiorkor and Marasmus are two types of malnutrition. All of the following are features of Kwashiorkor EXCEPT?
Kwashiorkor Marasmus 1. Edma Present Absent 2. Appetite Poor Voracious 3. CNS Apathy, Lethargy Active & Ale 4. Hepatomegaly Seen Not seen 5. skin & Hair Changes More common (Skin: Flaky Paint Dermatosis) (Hair: Flag sign) Less common
2
Child appears edematous
He has good appetite
He is apathetic and lethargic
Hepatomegaly may be seen
Pediatrics
Paediatrics
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multi
A 63-year-old man develops edema, and dyspnea on exertion. He has no prior cardiac or renal conditions, and his examination is significant for macroglossia, elevated jugular venous pressure (JVP), hepatomegaly, and 3+ pedal edema. His investigations reveal 3.5 g/d of protein in the urine, anemia, normal fasting glucose...
(a) Source: (Kasper, p. 2027) In addition to peripheral motor and sensory neuropathy, cardiac involvement, tongue enlargement, gastrointestinal (GI) manifestations, and carpal tunnel syndrome are also seen in amyloidosis. The specific diagnosis requires tissue biopsy with presence of amyloid with specific stains. In pr...
1
peripheral motor and sensory neuropathy
spinal cord compression in the lumbar region
spinal cord compression in the thoracic region
a peripheral neuropathy associated with cerebral manifestations
Medicine
Endocrinology
fce96470-4109-4080-99f8-479831d955cf
single
Rigler&;s Sign is seen in :
Pneumoperitoneum: Best projection to demonstrate pneumoperitoneum: Chest X-Ray If the patient cannot get into an erect position then left lateral decubitus projection is required Patient should be in that position for 10 minn at least for air rise up By careful technique even 1 ml of air can be detected Supine Film Sig...
4
Ulcerative colitis
Crohn's disease
Megacolon
Pneumoperitoneum
Surgery
G.I.T
858c3841-4d09-45d3-aaa9-63d93aeb8ef4
single
SARS causative agent -
null
1
Corona-virus
Picorna-virus
Myxovirus
Retrovirus
Medicine
null
350fb860-6433-4968-8a17-d56ed9c190f3
single
Rape is defined under:
Ans. (B). 375 IPC(Ref: The essentials of forensic medicine and toxicology; Dr. KS Narayana Reddy, 33rd edition; Page no: 411)According to 375 IPC, Sexual intercourse with a girl under 18 years of ageQ with or without her consent is statutory rape.The minimum age of wife to give consent for sexual intercourse is also 18...
2
Sec. 320 IPC
Sec. 375 IPC
Sec. 376 IPC
Sec. 351 IPC
Forensic Medicine
Law & Medicine, Identification, Autopsy & Burn
c63b2d76-7dfe-4dda-90e0-5872c9ac3151
single
True statement about paralysis of recurrent laryngeal nerve is
Paralysis of recurrent laryngeal nerve common on the left side. The common causes are Bronchogenic cancer Accidental trauma Thyroid surgery Thyroid disease (benign or malignant Cervical lymphadenopathy Carcinoma cervical oesophagus Carcinoma thoracic oesophagus Aoic aneurysm Mediastinal lymphadenopathy Ref: PL Dhingra ...
1
Common on left side
50% idiopathic
Cord will lie laterally
Speech therapy given
ENT
Larynx
6cada6ac-3f04-40c0-84f0-2f845a6a6c69
multi
A man has recurrent uicaria following exercise and coming out in sun. Diagnosis is:
Ans. a. Cholinergic uicaria Cholinergic uicaria develops due to acetyl choline liberated from post ganglionic cholinergic enervated sweat glands under the influence of any stimuli which induces sweating by increasing core body temperatureQ. Precipitating factors are exercise/physical exeiondeg, emotion upsetdeg, exposu...
1
Cholinergic uicaria
Atopic reaction
Photo dermatitis
Chronic idiopathic uicaria
Skin
null
c273e4b9-6df0-452a-8d92-d3f4169cc004
single
Scoring of palatal bar is
null
1
Limited to the area of soft displaced tissue
To increase the rigidity of the connector
Done on the entire posterior border of the bar
Done on the entire anterior border of the bar
Dental
null
da1ab4ca-5bea-4025-af7d-68426de2ce9a
single
Which of the following is not a feature of ASBESTOSIS?
Ans. c (Hilar adenopathy) (Ref.RRM Radiology, 6th ed., p. 463)ASBESTOSIS: Radiological featuresPleural changesPulmonary changesAsbestos-related Malignancy# Pleural Effusion (21%)# Focal Pleural Plaques (65%)# Pleural Calcification# Bilateral diaphragmatic calcifications with clear costophrenic angles are PATHOGNOMONIC#...
3
Pseudotumor of lung
Pleural plaques
Hilar adenopathy
Basal fibrosis
Radiology
Respiratory System
5b190eeb-1323-4b90-a23f-abd1ad29fd74
single
Patient is having normal CK & CKMB after 2 days of chest pain which of the following is true-
A significant concentration of CK-MB isoenzyme is found almost exclusively in the myocardium, and the appearance of elevated CK-MB levels in serum is highly specific and sensitive for myocardial cell wall injury. Normal reference values for serum CK-MB range from 3 to 5% (percentage of total CK) or 5 to 25 IU/L.if thes...
1
Excludes diagnosis of MI
Reperfusion after MI
Extracardiac source of pain
Cardiac surgery
Medicine
C.V.S
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multi
A 5 years old child presented to the OPD with complaints of rectal prolapse; On examination stunting and growth retardation was documented; What is the parasitological cause for this clinical feature
* Clinical features of rectal prolapse is a direct clue for diagnosis: Trichuriasis * This Infection is acquired by ingestion of soil with embryonated eggs (has rhabditiform larvae) * It usually affects children and remains asymptomatic * Heavy infection causes rectal prolapse in children; appendicitis; Lab diagnosis:-...
1
Trichuris trichura
Enterobius vermicularis
Giardia lamblia
Trichinella spiralis
Microbiology
parasitology
c692ec98-64d3-4fb7-9637-9898c69e3aca
single
Acetylcholine is the neurotransmitter in the cholinergic neurons. What is the precursor that acetylcholine is derived from?
The conversion of choline by CAT (choline acetyltransferase) is responsible for conveing choline to acetylcholine. Likewise, the conversion of acetylcholine back to choline is by ACH-ase (acetylcholine esterase). CAT ACh-ase Choline ----> Acetylcholine ----------> Choline
4
Dicholine
Tyrosine
Cholic acid
Choline
Biochemistry
null
41509342-a92f-4748-b3fc-7a13bad20d2a
single
Rocker bottom foot is due to -
Ans. is 'a' i.e., Overtreatment of CTEV Rocker bottom footo Rocker bottom foot is a foot with a convex plantar surface with an apex of convexity at the talar head (normal plantar surface is concave). Causes of Rocker Bottom foot areCongenital vertical talusOvercorrection of CTEVImproper correction of CTEV, i.e. forcefu...
1
Overtreatment of CTEV
Malunited fracture calcaneum
Horizontal talus
Neural tube defect
Orthopaedics
Lower Limb and Foot & Ankle Problems
5f41c0d4-43b9-4996-8e2a-eb831d8c4ad2
single
The inferior most structure of right hilum is
The inferior most structure of right hilum is inferior pulmonary vein. The sequence of structures at the right hilum superior to inferior is: Superior lobar (epaerial) bronchus. Pulmonary aery Principal bronchus Inferior pulmonary vein Ref: Gray&;s Anatomy 41st edition Pgno: 958
2
Right atrium
Inferior pulmonary vein
Pulmonary aery
Inferior bronchial vein
Anatomy
Thorax
964c949c-afff-4c27-b102-534c0f590141
single
Which of the following is associated with hypeensive pnemonitis:
Hypersensitivity pnemonotis describes a spectrum of immunoligically mediated,predominately interstitial lung disorders caused by intense often prolonged exposure to inhaled organic antigens. It is a type III +IV hypersensitivity reaction.(ref Robbins 7/e p733,9/e p688)
3
Silicosis
Asbestosis
Byssinosis
Berylliosis
Anatomy
Respiratory system
5791d84c-5b57-46cc-9d3c-b0bb9d1d74d5
single
A 21-year-old man has a nonproductive cough, shortness of breath, and chest pain, which changes with breathing. He also has pain in the left arm. On examination, there is tenderness over the left shoulder, heart sounds are normal, and the lungs are clear. CXR reveals a lytic lesion in the left humerus and reticulonodul...
Primary pulmonary Langerhans cell histiocytosis (PLCH), also called eosinophilic granuloma of the lung, pulmonary Langerhans cell granulomatosis, and pulmonary histiocytosis X, is an uncommon interstitial lung disease that primarily affects young adults. There is a coarse, reticular pattern in the whole lung, somewhat ...
3
lung biopsy
humerus bone biopsy
CT scan of chest
Bronchoscopy
Medicine
Respiratory
cbe0b35b-5343-4e6d-bb53-459176eaee2e
single
Enzyme of Pathway common to Glu- coneogenesis
Phosphoglycerate kinase (Pathway shown: Glycolysis)
4
Pyruvate kinase
PFK
Hexokinase
Phosphoglycerate kinase
Biochemistry
Gluconeogenesis
2a4127da-2d17-41a7-8061-1fda0bb3a16b
single
All of the following are the posterior relations of the kidney EXCEPT:
Nerves related to kidneys posteriorly are: Subcostal (T12), iliohypogastric (L1), and ilioinguinal (L1). Four muscles are in posterior relations of kidney: Diaphragm, quadratus lumborum, psoas major, and transversus abdominis. fig:- posterior relation of kidney
3
Psoas major
Quadratus lumborum
Sympathetic chain
Ilioinguinal nerve
Anatomy
Abdomen, Pelvis and Perineum
d9337ae9-5ec2-489c-b51d-b5e7a4c405c9
multi
Not used for intravascular volume maintainence is -
Ans. is 'c' i.e., Erythropoetin o Colloids the term 'colloids' refers to aqueous solutions that contain both large organic macromolecules and electrolytes. Presumably, the large molecular size of the dissolved molecules limited their ability to cross the endothelial membrane. These molecules are retained within the int...
3
Hydroxy ethyl starch
Dextran
Erythropoetin
Gelatin
Surgery
Fluids & Electrolyte Disorders - Volume
1e5618ba-c805-4aaf-9558-bb32394092ce
single
A 29-year-old man has developed marked joint pain beginning 12 days after receiving snake antivenom injection. On physical examination, there is diffuse joint pain with movement. The stool is negative for occult blood. Laboratory studies show a serum creatinine level of 4.4 mg/dL and urea nitrogen level of 42 mg/dL. Mi...
In the localized immune complex reaction (Arthus reaction) at the site of injection, there can be activation and depletion of complement C3. The reaction described here is serum sickness in response to the injected foreign protein, and produced more widespread antigen-antibody complex deposition, particularly in the ki...
2
CD4+ lymphocytosis
Hypocomplementemia
Increased IgE
Neutropenia
Pathology
Immunity
272a9cf1-05bf-4dd1-acb5-09f536f72f05
multi
A man presented with complaints of scanty, foul smelling, painless discharge from the ear. It is characteristic feature of the following lesion:
Patients with acquired cholesteatomas typically present with recurrent or persistent purulent otorrhea and hearing loss. The discharge is scanty & always foul-smelling due to bone destruction. Facial nerve twitching, palsy, or paralysis can also result from the inflammatory process or from mechanical compression of the...
2
ASOM
Cholesteatoma
Central perforation
Otitis externa
ENT
null
cf25d196-f3ec-43b5-8d43-e3a5e5e6f702
single
A woman with glucose-6-phosphate dehydrogenase (G6PD) deficiency develops a urinary tract infection. Free radicals generated by responding neutrophils create an oxidant stress, and RBCs are rapidly overwhelmed. As soon as intravascular hemolysis begins, serum levels of which of the following will decrease?
Haptoglobin (or alpha-2 globulin) is a serum protein that promptly binds to free hemoglobin in the serum, forming a tight complex. The haptoglobin-hemoglobin complex is quickly cleared from the blood by the reticuloendothelial system, which allows the hemoglobin to be salvaged instead of lost into the urine. Intravascu...
4
Bilirubin
C-reactive protein
Free iron
Haptoglobin
Medicine
null
004a2dda-28f5-42da-8a98-43cba9f0b2f4
single
Increased amylase may be seen in all of the following except:
Answer is B (Appendicitis) Appendicitis alone does not cause increased amylase. Perforated appendix, may be associated with increased amylase. Causes of Hyperamvlasemia and Hyperamylasuria: Pancreatiti Disease Non Pancreatic Disorders Other Abdominal Disorders I. Pancreatitis A. Acute I. Renal insufficiency II. Salivar...
2
Pancreatic pseudocyst
Appendicitis
Perforated peptic ulcer
Ruptured ectopic pregnancy
Medicine
null
34b6e2d1-a33a-4c25-9677-14e78b064a57
multi
Gleason score is used for prognosticating outcome of?
Ans. D. Prostatic cancer. (Ref. Bailey and Love 26th/pg. 98; 1352)Gleason scoreAdenocarcinomas are also often classified as Gl, 2 or 3, but prostate cancer is an exception with widespread use of the Gleason system. The Gleason system grades prostate cancer according to the degree of differentia- tion of the two most pr...
4
Gastric cancer
Bladder cancer
Colonic cancer
Prostatic cancer
Surgery
Prostate & Seminal Vesicles
f9bc1661-dbab-4cff-b8b0-25496753025d
single
In regeneration
ref, Robbins 8/e p92-94 .7/e p 88,9/e p101 When the injury is minimal, the tissue may effectively replace the damaged or lost cells . In severely damaged tissues or long-term chronic situations, the ability of the tissue toregenerate the same cell types and tissuestructure may be exceeded, so that a different and imper...
2
Granulation tissue
Repairing by same type of tissue
Repairing by different type of tissue
Cellular proliferation is largely regulated by biochemical factors
Anatomy
General anatomy
7913ebd4-8e36-4038-adbe-5449c6f387be
single
In jarjaway fracture of nasal bone, the fracture line is
Jarjaway' fracture of nasal septum occurs due to blows from the front. Fracture line stas just above the anterior nasal spine and runs horizontally backwards just above the junction of septal cailage with the vomer. Ref: Textbook of ENT; PL Dhingra;7th edition, pg no.165
4
Oblique
Comminuted
Veical
Horizontal
ENT
Nose and paranasal sinuses
5e4904dc-3023-4861-8cc6-5407e28199f4
single
Spine of Henle is a:
Spine of henle is a pa of mastoid bone. Mastoid is a spongy or cancellous bone, hence spine of henle is also cancellous.
2
Coical bone
Cancellous bone
Sclerotic bone
Long bone with Haversian system
ENT
null
0e5e04c3-f00f-433b-a675-c757a5f8e1ad
single
Severe hepatotoxicity associated with steatohepatitis, most likely a result of mitochondrial toxicity, is being recognized with:
Severe hepatotoxicity associated with steatohepatitis, most likely a result of mitochondrial toxicity, is being recognized with increasing frequency with antiretroviral therapy with reverse transcriptase inhibitors (e.g., zidovudine, didanosine) or protease inhibitors (e.g., indinavir, ritonavir. Reference: Harrisons P...
4
Zidovudine
Didanosine
Indinavir
All
Medicine
null
a1b18367-7754-4da5-8aa2-ad1205050240
multi
A 22 years old primigravida presents with suicidal tendency and severe depression in the 1st trimester. Treatment of choice is:
(Refer: Kaplan & Saddock's  CTP P.3290 chap. 31.34a) (Refer: The Maudsley Prescribing Guidelines 11th Ed  In Psychiatry Chap .7 P.430) Since, It is a Primigravida with suicidal tendencies here the therapeutic effect has to be immediate . considering the risk of suicide, medications in first trimester ECT is preferred o...
1
Electroconvulsive therapy
No treatment is necessary
Imipramine
Lithium
Unknown
null
159b9268-2355-4f37-92a4-4849a3c71543
single
Which of the following is Iso-osmolar agent?
- Ionic Monomer - High osmolality contrast media - Ionic Dimer - Low osmolality contrast media - Non-ionic Monomer - Low osmolality contrast media - Non-ionic Dimer - Iso osmolality contrast media
4
Ionic monomer
Ionic dimer
Non-ionic monomer
Non-ionic dimer
Radiology
Contrast Agents
cf3e660d-62aa-4a22-88ae-7a23d2999513
single
Following hormonal levels are increased in small cell carcinoma of lung except
Hormones produced by small cell variant ACTH AVP ANF calcitonin Gastrin relesinre peptide Ref Harrison 19th edition pg 541
2
ACTH
Growth hormone
ANF
AVP
Anatomy
Respiratory system
bd96cee0-2918-4303-9ab5-c5eceae09460
multi
Diagnostic test for HIV in window period is?
ANSWER: (C) P 24 antigenREF: Harrisons Internal Medicine 17,h edition Chapter 182. Human Immunodeficiency Virus Disease: AIDS and Related DisordersIn June 1996, blood banks in the United States added the p 24 antigen capture assay to the screening process to help identify the rare infected individuals who were donating...
3
ELISA
Western blot
P 24 antigen
Viral load
Medicine
Virology
a69bc4e5-ac36-4050-b605-735517e76573
single
RhabdomyolyMis with myoglobinuria seen in -
Rhabdomyolysis is a serious condition, with destruction of striated muscles, and can be induced by various causes such as drugs, hea attacks, CRASH syndrome, and viper bites. Mass envenomation by multiple wasp stings can also cause rhabdomyolysis followed by acute renal failure, although it is extremely rare. Ref Harri...
4
Viper bite
Heat stroke
Malignant hypehcnnia
Multiple hornet stings
Medicine
Kidney
e1b6d0ac-c5ed-4602-bf30-43c35db96a00
single
All are are features of trachoma except
Trachoma is characterized by conjunctival congestion. It causes keratitis, cicatrization and follicle ciliary congestion,and corneal is not a feature of conjunctivitis refer :Khurana 6th edition page number 65
1
Circumcorneal congestion
Follicle
Cicatrization
Keratitis
Ophthalmology
Conjunctiva
36ae674d-4dc0-46f6-927d-1796fff585f3
multi
Tendon of which of the following muscle can be felt at radial border of the anatomical snuff box.
Extensor pollicis bravis. BOUNDARIES OF ANATOMICAL SNUFF BOX The posterior border of the snuffbox is the tendon of the extensor pollicis longus. The anterior border (closest to the edge of the hand) is a pair of parallel and intimate tendons, of the extensor pollicis brevis and the abductor pollicis longus. (Accordingl...
2
Extensor pollicis longus
Extensor pollicis bravis
Extensor pollicis ulnaris
Extensor digitorium
Surgery
null
fe38d685-743f-4dbe-827b-b62005ec154a
single
All of these are physiological changes in pregnancy except?
There is decrease in platelet counts in pregnancy which is also known as gestational thrombocytopenia Lower platelet concentrations are paially due to hemodilution Platelet consumption is likely augmented because of splenic enlargement There may be an element of "hypersplenism," in which platelets are prematurely destr...
3
Increase in blood volume by 30-40%
Serum fibrinogen increases by 50%
Increase in platelet count
Decrease in packed cell volume
Gynaecology & Obstetrics
Physiological Changes of Pregnancy
406cf8db-48d8-47f8-8124-3dd1ea9113bf
multi
______ muscle pulls the tongue upwards and backwards during swallowing:
null
4
Hyoglossus
Palatoglossus
Superior longitudinal
Styloglossus
Anatomy
null
f5153d1d-ee92-4861-9965-d9a7fe7734f8
multi
Calculous cholecystitis is associated with all of the following except: March 2005
Ans. D: Diabetes Risk factors for calculous cholecystitis mirror those for cholelithiasis and include the following: Female sex Ceain ethnic groups Obesity or rapid weight loss Drugs (especially hormonal therapy in women) Pregnancy Increasing age
4
Oral contraceptives
Oestrogen
Obesity
Diabetes
Surgery
null
1ab15c10-c070-409b-b46b-8eab35b32d19
multi
Characterized by chronic, multiple tics ?
Ans. D. Tourette's syndromeTourette syndrome (also called Tourette's syndrome, Tourette's disorder, Gilles de la Tourette syndrome, GTS or, more commonly, simply Tourette's or TS) is an inherited neuropsychiatric disorder with onset in childhood, characterized by multiple physical (motor) tics and at least one vocal (p...
4
Parkinson's disease
Wilson's disease
Shy-Drager syndrome
Tourette's syndrome
Psychiatry
null
70aba217-cb64-4a29-9e51-09e549b99033
single
Treatment of nasopharyngeal carcinoma T1 -
Overall treatment of choice for nasopharyngeal carcinoma → radiotherapy. Treatment of choice for early (stage I & II) nasopharyngeal carcinoma → radiotherapy. Treatment of choice for advanced (stage III & IV) nasopharyngeal carcinoma → radiotherapy combined with chemotherapy.
1
Radiation therapy
Surgery
Local resection
Chemotherapy
ENT
null
47342dce-7670-4aaa-a27d-324855b49923
single
Gonorrhea is assumed to be caused by gonococcus. Gonococcus can be identified by being:
By the fermentation of glucose
3
By the growth on McConkey medium
By the fermentation of maltose
By the fermentation of glucose
Gram positive
Microbiology
null
edb80eb8-1fc8-4e1a-a5eb-dfc85e5dcbc2
single
Identity the true statement about Pulmonary embolism:
S1 Q3 T3 is highly predictive sign but not the most common ECG finding. And there will be right axis deviation. D-Dimer is best for screening not gold standard investigation.
4
S1 Q3 T3 is the most common ECG finding seen
There will be Left axis deviation
D-dimer is the gold standard investigation
Sinus tachycardia is most common finding on ECG
Surgery
null
3099ddd1-42bf-48a7-a4be-9852cd99840f
multi
Sharp instruments may be sterilized with-
Hot air is useful for sterilizing aicles such as glassware, syringes, swabs, dressing, French chalk oil , Vaseline and sharp instruments. The drawback of hot air is that it has no penetrating power and is not suitable for disinfection of bulky aicles such as mattresses Ref: 25th edition, Park's Textbook of Preventive a...
3
Radiation
Lysol
Hot air
Any of the above
Social & Preventive Medicine
Epidemiology
fea15bca-f797-4171-8626-125c4267812f
multi
Bleeding in haemophilia A is due to:
Ans: c (Deficiency of factor 8 which fails to activate factor 10) Ref: Harrison, 16th ed, p. 680; 17th ed, p. 726Haemophilia A occurs due to deficiency or reduced activity of factor 8 which is responsible for activation of factor 10. The intrinsic pathway of coagulation is affected.Haemophilia B or Christmas disease oc...
3
Deficiency of factor 7 which fails to convert fibrinogen to fibrin
Deficiency of factor 9 which fails to activate factor 10
Deficiency of factor 8 which fails to activate factor 10
Defect in extrinsic pathway
Medicine
Blood
29ec5d03-2d3d-491c-9641-88ef24b156ea
single
A child presented with headache, dizziness, intermittent claudication with occasional dyspnoea.The most probable diagnosis in –
Clinical manifestations of COA Symptoms of coarctation of aorta occurs due to decrease in blood supply distal to aortic obstruction. If obstruction is distal to left subclavian artery, manifestations are due to arterial insufficiency to lower limbs. Intermittent claudication Pain Weakness of Leg Dysnea on running Wea...
4
ASD
PDA
TOF
Coarctation of aorta
Pediatrics
null
b40630f9-5cd3-4386-9ddf-efe75854028a
single
Most Commmon cause of chronic osteomyelitis -
Ans. is 'a' i.e., Staphylococcus aureus o Chronic osteomyelitis is nearly always a sequel to acute osteomyelitis,o Occasionally infection is subacute or chronic from the begining.o As with acute osteomyelitis, the most common causative organism is staphylococcus areus.
1
Staphylococcus aureus
Streptococcus pyogenes
Mycobacterium tuberculosis
Staphylococcus epidermidis
Orthopaedics
Infection of Bones & Joints
14be05c2-9d2d-4d27-a942-57f87e00641b
single
What percentatge of the healthcare waste generated is infectious?
- about 80% of health care wastes accounts for general health care wastes. - 1% accounts for sharps - 15% is pathological and infectious wastes. - 3% chemical and pharmacological wastes. Reference : Park's textbook of preventive and social medicine, 23rd edition, pg no:790 <\p>
1
10% - 15%
50%
75%
100%
Social & Preventive Medicine
Hospital waste and disaster management, Occupational health
2473f815-4f9e-4171-9d61-d11e94d9df30
single