question
stringlengths
1
1.57k
exp
stringlengths
1
22.5k
⌀
cop
int64
1
4
opa
stringlengths
1
287
⌀
opb
stringlengths
1
287
⌀
opc
stringlengths
1
286
⌀
opd
stringlengths
1
301
⌀
subject_name
stringclasses
21 values
topic_name
stringlengths
3
135
⌀
id
stringlengths
36
36
choice_type
stringclasses
2 values
In which of the following cases, apical diastolic murmur occur:
null
2
Mital regurgitation
Mitral stenosis
Aortic stenosis
Ventricular septal defect
Medicine
null
40085990-6ba6-483c-9bf8-7d1305bf4bda
single
After curettage, restoration of junctional epithelium occurs after:
Resorption Re-epithelization of sulcus : After 2-7 days. Restoration of junctional epithelium : After 5 days. Immature collagen fibers after 21 days.
2
3 days
5 days
7 days
21 days
Dental
null
18ae73c2-2d0b-4477-8678-08781b8e7f3b
single
The hyperkinetic disorder is characterised by all, except-
Characteristic triad of hyperkinetic disorder (Attention deficit hyperactivity disorder) includes Hyperactivity, impulsiveness and inattention (distractibility or lack of concentration).
4
Impulsivity
Distractibility
Hyperactivity
Hallucinations
Psychiatry
null
2bad2453-6fd0-4b95-b779-a89345f7b8a0
multi
Deficiency of enzyme hexosaminidase, n subunit causes -
Ans. is 'a' i.e., Tay- Sach's disease
1
Tay-Sachs disease
Hurler syndrome
Fabry disease
Pompe disease
Pathology
null
b9062d9d-752b-4e9c-900f-46d0c9aa3647
single
Which is the drug of choice for maintenance therapy in uncomplicated bipolar disorder ?
null
3
Sodium valproate
Carbamazepine
Lithium
Lamotrigine
Pharmacology
null
93383df3-19c9-4f1e-977b-06e60f831f32
single
Which of the following drug does not cause edema?
Ans. b. Digoxin (Ref: Katzung 12/e p1036-1037; http://www.drugs.com/sfx/digoxin-side-effects.html; http://www.drugs. com/sfx/cyclosporine-side-effects. html)Digoxin does not cause edema.Digoxin Side effectsCommonRareNot known to occur* Dizziness* Fainting* Fast, pounding, or irregular heartbeat or pulse* Slow heartbeat...
2
Amlodipine
Digoxin
Estrogen
Cyclosporine
Pharmacology
Adverse Drug Effect
3bf60585-aee9-4810-945d-aba1e02abbb3
single
Q fever is transmitted by -
<p> Q fever:- Highly infectious zoonotic disease with world wide distribution. Occurs mainly in persons associated with sheep, goat ,cattle etc. Causative agent-Coxiella burnetti. It is found in ticks which act as vectors as well as reservoirs. Animal host- cattle,sheep, goat, ticks etc. The placenta of infected cows a...
1
Ticks
Mites
Louse
Flea
Social & Preventive Medicine
Communicable diseases
1f034fd7-699b-4627-8e96-cc2fc90e8dc8
single
Excitatory post synaptic potential is
EPSP: Depolarisation of post synaptic membrane by opening of Na+ or Ca2+ channels IPSP : Hyperpolarisation of post synaptic membrane by opening of Cl- or K+ channels
3
Depolarisation of post synaptic membrane by opening of K+ channels
Hyperpolarisation of post synaptic membrane by opening of Cl- channels
Depolarisation of post synaptic membrane by opening of Ca2+ channels
Hyperpolarisation of post synaptic membrane by opening of Na+ channel
Physiology
null
88284e86-48b5-4d5d-988f-98517a27074b
single
A three and half-year-old male child, who presented with characteristic self-mutilating behavior. He had history of developmental delay, difficulty in social interaction, attention deficit and features of autism. His serum blood biochemistry was normal except for low hemoglobin levels and raised serum uric acid levels....
The above features suggests diagnosis of Lesch-Nyhan syndrome is X-linked recessive disorder associated with a viually complete deficiency of Hypoxanthine-guanine phosphoribosyltransferase (HGP). This deficiency results in an inability to salvage hypoxanthine or guanine, from which excessive amounts of uric acid, the e...
3
Adenosine kinase
AP
HGP
Adenosine deaminase
Biochemistry
Metabolism of nucleic acids
7b475364-475b-4583-9618-94c1ca3455d6
multi
Most common type of colour blindness is:
Ans. Protanopes
1
Protanopes
Deuteranopes
Tritanopes
null
Ophthalmology
null
e6900eeb-ec3a-4aec-873e-ad9afd6af38e
multi
Epidemic typhus is cause by -
Ans. is 'b' i.e., R. prowazeki DiseaseAgentInsect vectorMammalian reservoir1.Typhus group a. Epidemic typhusR. prowazekiiLouseHumans b. Murine typhus (Endemic typhus)R. typhiFleaRodents c. Scrub typhusR. tsutsugamushiMiteRodents2.Spotted fever group a. Indian tick typhusR. conoriiTickRodents, dogs b. Rocky mountain spo...
2
R.typhi
R.prowazeki
R.rickettsii
R.tsutsugamushi
Microbiology
Bacteria
1ad9a4b9-b94d-44d5-b4c5-cf8a072ea1a2
single
Pulmonary hypertension may occur in all of the following conditions except -
null
4
Toxic oil syndrome
Progressive systemic sclerosis
Sickle cell anemia
Argemone mexicana poisoning
Medicine
null
761278a2-7c68-49b5-9971-ce0c7fcdd27a
multi
Essential pentosuria can occur due to deficiency in metabolic pathway of
Ans. a (Uronic acid) (Ref. Harper's Biochemistry-26th/pg. 105, 163, 170; 27th/pg. 177)Glucuronic acid is synthesized from glucose via the uronic acid pathway, of major significance for the excretion of metabolites and foreign chemicals (xenobiotics) as glucuronides. A deficiency in the pathway leads to essential pentos...
1
Uronic acid
Hexose-mono-phosphate
Glycogen
Fructose
Biochemistry
Carbohydrates
97813adf-0c84-4c2b-8ff2-0b7568055597
single
The slogan for WHO 2005 -
Ans. is b' i.e., Maternal & Child health Year
2
Road safety
Maternal and child health
Aging
Physical activity
Social & Preventive Medicine
null
2b69c0bb-86bf-4df7-a226-8d43cfda23ec
single
A 6 year old child presents with pallor that required two blood transfusions previously. He has now developed fever and petechial haemorrhages.His hemoglobin is 9 g/dL, platelet count is 20,000/mm3 and TLC is 60,000/ mm3. Flow cytometry reveals the cells to be CD10 +ve, MPO +ve, CD 19 +ve, CD 33 –ve, CD 117 +ve, and CD...
Mixed lineage acute leukemia is alternatively also known as bilineal acute leukemia. As suggested by the name, there are 2 populations of cells which are morphologically and immunophenotypically distinct from each other. Analyzing the markers on the cells, B lymphoid markers: CD10, CD19 and CD79. T lineage markers: CD...
3
ALL
AML
Mixed phenotypic leukaemia
Undifferentiated leukaemia
Pathology
null
8d8000f1-5586-40cc-8cd4-1d893e175086
multi
The Eustachian tube passes between -
GAPS BETWEEN PHARYNGEAL MUSCLES AND RELATED STRUCTURES I. Between the base of the skull and superior constrictor i.e. above superior constrictor (Sinus of Morgagni) : Levator veli palatini Auditory tube(eustachian tube) Ascending palatine artery II. Between superior and middle constrictors : Stylopharyngeus muscle G...
2
Superior and middle constrictors
Above superior constrictor
Middle and inferior constrictor
Below inferior constrictor
Anatomy
null
c2353788-12df-4064-b68c-00b7b575deef
multi
A patient presented with complaints of ipsilateral flushing and sweating with eating and salivation. He had a parotid gland surgery few weeks ago. Frey's syndrome is diagnosed. Frey's syndrome is related to:
Frey syndrome: Aberrant nerve regeneration after parotid gland injury or surgery may result in ipsilateral flushing and sweating with eating and salivation. Sweating occurs in the distribution of the auriculotemporal nerve after an injury, abscess, or surgery in the parotid region. Freys syndrome can be seen in infants...
1
Auriculotemporal nerve
Facial nerve
Abducens nerve
Glossopharyngeal nerve
ENT
null
dd0e68b5-af55-459f-ac2a-8fb9c10fb9c4
single
All are ocular emergencies except -
Central serous retinopathy (CSR) is typically a self limiting disease and undergoes spontaneous resolution in 80 to 90% of cases. Ocular emergencies Closed - angle glaucoma                                                    Retinal detachment                           Foreign body      Orbital fractures           Co...
2
Angle closure glaucoma
Central serous retinopathy
Retinal detachment
Central retinal arterial occlusion
Ophthalmology
null
43a03f7e-1632-4a97-b9f6-25db7da2669e
multi
Transitional cell carcinomas can be caused by -a) Napthylamineb) Smokingc) Bilharziasisd) Betel nut
null
1
abc
bc
acd
bcd
Pathology
null
f8d7429b-e056-48bb-aea6-d575ec93a7be
single
Regarding Lichen Planus all are true, except :
A. i.e. Hypopigmentation in residual disease
1
Hypopigmentation in most residual disease
Lymphatic infiltration in supradermal layer
Itchy polygonal, purple papule
Skin, hair and oral mucosa commonly involved
Skin
null
ef6e2017-309c-4f6d-aacc-e022d4ec59e2
multi
The ideal treatment for metastatic choriocarcinoma in the lungs in a young women is :
Ans. is a i.e. Chemotherapy "Unlike other malignant lesion, the treatment of choriocarcinoma is mainly chemotherapy, both for local and distant metastasis." Note : Treatment of malignant trophoblastic disease must be continued with repeated courses of combination chemotherapy until p HCG titres return to nondetectable ...
1
Chemotherapy
Surgery with radiation
Surgery
Wait and watch
Gynaecology & Obstetrics
null
4a3f5498-c3f3-42e9-9515-929446da93e1
single
Which of the following is true about splenic artery?
Splenic artery branches from the celiac artery and follows a course superior to the pancreas. Splenic artery gives off branches to the stomach and pancreas before reaching the spleen. The short gastric artery is through the upper part of the greater curvature of stomach and fundus of the stomach. Some other branches ar...
2
Smaller than left gastric artery
Gives short gastric arteries along the fundus
Curves around the fundus
Arises from abdominal aorta
Anatomy
null
fef9d0a7-3597-4481-a1b1-e305ca357500
multi
A 28-year-old female visits the outpatient clinic to receive the required physical examination for an insurance policy. Physical and laboratory examinations give evidence that she is probably a normal, healthy woman. A radiograph of the patient is shown. Which of the following is the most likely diagnosis?
(c) Source: GAS 316-317; GA 142-143, 162 Because physical and laboratory tests show a normal, healthy woman, the anomaly of the radiograph would be expected to be benign. Riedel's lobe is a normal variation of the liver, often an inferior extension of the right lobe of the liver, lateral to the gallbladder that extends...
3
Cholecystitis
Carcinoma of the liver
A caudal extension of the right hepatic lobe (Riedel lobe)
Pancreatic carcinoma
Anatomy
Abdomen & Pelvis
29c059eb-d1c8-4cde-9359-0979592ebefa
single
1st evidence of calcification of Primary Mandibular 2nd molar is seen in
null
4
14 wk IU
16 wk IU
17 wk IU
18-19 wk IU
Dental
null
cb75f721-d731-4f92-a6d2-e195743d0213
single
Seizures caused by ciprofloxacin are exacerbated when which drug is given concomitantly?
K.D Tripathy essentials of medical pharmacology 7th edition . *NSAIDs can enhance the CNS toxicity of FQs (ciprofloxacin):seizures are repoed.
3
Nifedipine
Steroids
Aspirin
null
Medicine
C.N.S
263550a5-11dc-4f9b-abb5-95cf1c8c6171
multi
Features of essential hypeension-
Ans. is `a' i.e., Concentric hyperophy of LV; 'b' i.e., T hea size; 'c' i.e., ls Size of hea muscleAdaptations in hea The cardiac myocyte is terminally differentiated cell that is not able to divide.Myocardium cannot undergo hyperplasia, i.e. increase in the number of myocyte.So, myocardium can adapt by increasing the ...
4
Concentric hyperophy of LV
Ted hea size
Ted size of the hea muscles
All
Pathology
null
a41bd492-2404-44b1-aa05-41b975a40e13
multi
Which of the folowing statements about calendar method (Rhythm method) is false :
Ans. is a i.e Abstinence is needed for only a few days in the month Calendar method or Rhythm method Basis - avoidance of sexual intercourse around ovulation In a 28 days cycle ovulation normally occurs on the 14" day of cycle, but may occur at anytime between the 12" and 16'h day. Spermatozoa deposited in female genit...
1
Abstinence is needed for only a few days in a month
It is associated with no costs
Safe period can also be observed using temperature rhythm or mucous method
Ectopic pregnancy is a repoed complication of calendar method
Gynaecology & Obstetrics
null
b7e1737c-69f2-4188-85bf-9363bef88811
multi
The child can Imitate scribbling at the age of ________
Emerging patterns of Adaptive milestones from 1-5years of age 15months Makes a tower of 3 cubes Makes a line with a crayon Inses raisin in a bottle 18months Makes a tower of 4 cubes Imitates scribbling Imitates veical stroke Dumps raisin from a bottle 24months Makes a tower of 7 cubes (6 at 21 mo) Scribbles in a circul...
3
12 months
15 months
18 months
24 months
Pediatrics
Growth and development
4849f424-0807-490b-bed2-73146c839184
single
Gland of Moll opens in/on the ?
Ans. is 'b' i.e., Hair follicle GLANDS OF EYELIDS : Meibomian glands : These are also known as tarsal glands and are present in the stroma of tarsal plate arranged veically. They are modified sebaceous glands. Their ducts open at the lid margin. Their secretion constitutes the oily layer of the tear film. Glands of Zei...
2
Skin
Hair follicle
Tarsal plate
Ducts of Meibomian glands
Ophthalmology
null
c84348ab-ca4d-4452-aa87-7d27b84a4770
single
Interferon is used in - a) CML b) Multiple myeloma c) Small cell Ca of lung d) Non small cell Ca of lung e) Renal cell Ca
null
1
abe
acd
ab
cd
Medicine
null
cfdac910-d272-4c2d-94e7-ecff4e32aacc
multi
Geniculate ganglion is concerned with
null
1
Taste
Lacrimation
Saliva
Sweating
Anatomy
null
ccbf9525-5b17-49dd-918c-e663fb827674
single
Borrelia undergoes antigenic variation due to:
Ans. is. 'a' i. e., Plasmids
1
Plasmids
Transposons
Intrinsic mutation
All of the above
Microbiology
null
32f54068-675d-4d1a-a8b5-1606bb3e20ba
multi
A 60-year-old man from a poor socioeconomic environment is admitted with an acute illness characterized by mental disturbances. On examination, he has bilateral sixth nerve palsy and an ataxic gait. Which of the following is the most appropriate treatment?
The patient has Wernicke's encephalopathy and requires treatment with thiamine. A delay of a few hours may permit progression to psychosis. The eye findings in Wernicke's encephalopathy include bilateral (but not necessarily symmetrical) abductor weakness or paralysis, horizontal diplopia, strabismus, and nystagmus. Th...
1
thiamine
lecithin
vitamin D
phenytoin
Medicine
C.N.S.
c53b856a-255b-4538-a137-494dd183d69b
single
Lipofuscin is associated with-
Ans is 'a' i.e. Brown atrophy o Deposition of lipofuscin in the heart is referred as brown atrophy.
1
Brownatrophy
White atrophy
Red atrophy
Black atrophy
Pathology
Intracellular Accumulations
a98304d6-2e33-4bb3-a847-7ed561455e70
single
All are measures of primordial prevention of hypeension, except -
Primordial prevention is to reduce the incidence of a disease in a population by reducing the risk of onset i:e, restrain smoking, regular exercise, dietary changes. *Identification of Hypeensive is secondary prevention. Ref- Park&;s textbook of Preventive and Social Medicine 24th edition. .
3
Dietary changes
Restrain smoking
Identification of hypeensive
Regular physical exercise
Social & Preventive Medicine
Non communicable diseases
e396e97e-489b-4f46-b047-247ec734ee7e
multi
Retarder in zinc oxide eugenol is
Setting Time and Factors Affecting ZOE: The normal reactivity between zinc oxide and eugenol is very limited and must be accelerated in order for the material to have a practical clinical application. Acceleration of the set may be achieved by: Incorporating chemical accelerators in the mix (the most efficient and pre...
4
CaCl2
Zinc acetate
Alcohol
Glycerine
Dental
null
1b69faa1-8106-4983-b311-a5ea7228af3e
single
Amphotericin B has the following unwanted effects
Renal impairment occurs in nearly all patients treated with clinically significantdoses of amphotericin.. varying degree of anaemia due to reduced erythropoietin production by damaged renal tubular cellsBasic and clinical pharmacology Katzung 13th edition pg 828
2
Psychosis
Renal impairment, anaemia
Hypeension, cardiac arrhythmia
Bone marrow toxicity
Pharmacology
Chemotherapy
001f01e5-0072-401b-a5da-f9b65e2ef06f
single
Retina is part of-
Ans. is 'a' i.e., CNS * Retina is a part of CNS and develops along with CNS.* Retina develops from walls of optic cup. The outer thinner layer becomes retinal pigmented epithelium and inner thicker layer forms neural layer of retina.
1
CNS
PNS
ANS
null
Physiology
Nervous System
3aff7bc0-ace0-4da6-a54a-e9148868b328
multi
Flumazenil used in:(1640-CMDT-2007) (400-KDT 6th))
(Benzodiazepine overdose) (2568-H 16th) (1389-CMDT-2009) (400-KDT 6th)FLUMAZENIL - may reverse benzodiazepine induced coma flumazenil should NOT be given if the patient has coingested atricyclic antidepressant, is a user of high dose benzo diazepines or has a seizure disorder - precipitale seizures.* Flumazenil is a GA...
1
Benzodiazepine overdose
Lithium toxicity
Tricyclic anti depresants
Cyanide poisoning
Medicine
Drugs
7656387a-e874-4342-9d4c-de9a5b3e6874
single
TOS for penicillin resistant gonorrhoea
Complicated gonococcal infections ate treated with ceftriaxone1 g IM OD x 7 days. Or cefixime 400 mg BD X 7days. From illustrated synopsis of dermatology and sexually transmitted diseases neena khanna 5th edition page no 338
2
Ciprofloxacin
Ceftriaxone
Streptomycin
Erythromycin
Dental
Sexually transmitted diseases
ec9f079c-1994-4bbd-b1a3-585d661ae6a1
single
Drug not given for malaria prophylaxis is :
null
4
Chloroquine
Proguanil
Doxycycline
Artesunate
Pharmacology
null
aad3f9b6-ae42-4ce4-a5c1-3bf60fac0cb1
single
Changes in middle ear after birth are observed in-
Ans. is 'a' i.e., Werdin's test * Werdin's test: Before birth middle ear contains gelatinous embryonic tissue which is replaced by air after respiratioTests used in infanticidePloucquet's test:* Weight of lung is measured in relation to body wieght. Before birth weight of lung is 1/70 of body weight and after respirati...
1
Werdin'stest
Ploucquet's test
Fodere's test
Breslau's test
Forensic Medicine
Law & Medicine, Identification, Autopsy & Burn
44d594d5-441f-495c-977a-f820fe31f905
single
25 year old labourer 3 years back presented with penile ulcer not treated. Later he presented with neurological symptoms for which he got treated. Test to monitor response to treatment is ?
Ans. is 'a' i.e., VDRL . Neurological symptoms in a patient with history of untreated ulcer 3 years back suggests the diagnosis of neurosyphilis. To fuher clear the doubts, all the given options are serological tests for syphilis. So, the examiner is asking about the syphilis for sure. . It has alreadys been explained ...
1
VDRL
FTA-ABS
TPI
RPR
Microbiology
null
391aceb0-97a8-4c1e-87c8-db16a278691b
single
Vidya, a 3 years old comes for her pre dental visit. She is highly intelligent with family members of high I.Q. you would do most probably what type of treatment
null
2
Radiographs and topical flouride
Get the patient accustomed to the dental clinic
Employ desensitization
Employ behaviour modification
Dental
null
efb94eec-e9fd-48d4-b826-7f9c1626ab63
single
Iodine deficiency or goitrogenic drugs administered over a long period may produce:
null
3
Follicular carcinoma.
Medullary carcinoma.
Papillary carcinoma.
Anaplastic carcinoma.
Surgery
null
bbf200ec-d9b5-4dd3-83cb-52e8ed3bf926
single
Transverse fracture of the patella with separation of fragments is best treated by
D i.e. Open reduction with Kirschner wire fixation of the fragment an tension band wiring
4
Closed reduction with cylinder cast
Open reduction with screw fixation of the fragments
Blind fixation of the two fragments with Kirschner wire
Open reduction with Kirschner wire fixation of the fragment an tension band wiring
Surgery
null
644259ba-61d1-4ae8-a059-eeb2952401fb
single
What is the most common presentation in cystic fibrosis?
Feature Percentage of cases Acute or persistent respiratory symptoms 50.5 Failure to thrive, malnutrition 42.9 Abnormal stools 35.0 Meconium ileus, intestinal obstruction 18.8 Family history 16.8 Electrolyte acid-base abnormality 5.4 Nasal polyps; sinus disease 2.0 Hepatobiliary disease 0.9
1
Lung infection
Meconium ileus
Malabsorption
Infeility
Medicine
Cystic fibrosis & Sleep apnea
d39fe936-4b15-45a4-9845-22449af1e9c0
single
Protein A of staph aureus is part of bacterial?
ANSWER: (B) Cell wallREF: Jawetz Microbiology, 24th Ed, Ch. 20Protein A is a cell wall component of many S aureus strains that binds to the Fc portion of IgG molecules except IgG3. The Fab portion of IgG bound to protein A is free to combine with a specific antigen. Protein A has become an important reagent in immunolo...
2
Genome
Cell wall
Limiting membrane
Plasmid
Microbiology
Staphylococci
a727225c-cae4-4d87-8c41-525d2832b87c
multi
A 6 year old female child reported with a chief complaint of proclined upper anteriors. Parents give a history of prolonged bottle-feeding and a persistent thumb sucking habit. Clinical examination reveals anterior open bite with proclined upper anterior and retroclined lower anterior teeth and associated tongue thrust...
Approach to Thumb-sucking treatment During treatment, the child should be given an opportunity to stop the habit spontaneously before the permanent teeth erupt. Delay until the early school-age years, allows spontaneous discontinuation of the habit due to peer pressure. If it is not discontinued, the treatment should g...
3
No treatment. Wait and watch
Extraction of first premolars followed by Hawley's appliance
Psychiatric consultation prior to any therapy
Extraction of second premolars followed by Hawley's appliance
Dental
null
a1d0ff49-baf3-42c6-bf50-a3dd0e025262
single
Bidextrous grasp is seen at what age?
3 months - Holds an object when placed in hands 4 months - Tries to reach for an object, but overshoots 5 months - Bidextrous grasp 6 months - Unidextrous/palmar grasp 7 months - Transfers objects from 1 hand to another 9 months - Immature/Assisted pincer grasp 12 months - Mature/ Unassisted pincer grasp
2
3 months
5 months
6 months
9 months
Pediatrics
NEET 2019
18862e73-cd12-48bb-a127-62adae7e693c
single
Which of the following drugs cause oligospermia ?
Sulfasalazine can cause a reversible infertility in males owing to changes in sperm number and morphology.
4
Leflunomide
D - Penicillamine
Methotrexate
Sulfasalazine
Pharmacology
null
a18a833f-59e8-445d-a62d-5f430464a690
single
Risk of transmission from single percutaneous exposure to blood for HIV is:-
Risk of transmission from single percutaneous exposure to blood for: * HBV: 6-30% * HIV: 0.1-0.36% * HCV: 2.7-10%
2
6-30%
0.1 - 0.36%
2.7-10%
0.4-5%
Medicine
viral infection
f1e3c11b-4731-451d-b73e-7928ed4e867a
single
A 5-year-old residential school child walks in to your clinic with the habit of thumb sucking in association with bruxism What would be probable cause
null
4
Food habits
Nasal septal deviation
Habitual
Psychological
Dental
null
7ed5aa30-1249-4602-a4a2-5ab13ea0842c
single
True about pain of pericarditis is -a) Pain increase on leaning forwardb) Pain decreasing on supine positionc) Pain increases during inspirationd) Pain increasing on eating
null
4
ab
bc
bd
cd
Medicine
null
6b826135-95fd-4dc5-ba90-fb971222d815
multi
A single cell within a culture of freshly isolated cardiac muscle cells is injected with a fluorescent dye that cannot cross cell membranes. Within minutes, several adjacent cells became fluorescent. The most likely explanation for this observation is the presence of
Gap junctions are pores composed of paired connexons that allow the passage of ions, nucleotides, and other small molecules between cells.Ref: Guyton; 13th edition
1
Gap junctions
IP3 receptors
Transverse tubules
Desmosomes
Physiology
General physiology
cea08de0-cb99-45e5-a953-25bbcd774ab0
single
Causative agent of Yaws is?
ANSWER: (A) Treponema pertenueREF: Harrison's 17th ed table 163-1FeatureVenereal SyphilisYawsEndemic SyphilisPintaOrganismT. pallidum subsp. pallidumT. pallidum subsp. pertenueT. pallidum subsp. endemicumT. carateumMode of transmissionSexual, transplacentalSkin-to-skinHousehold contacts: mouth-to-mouth or via shared dr...
1
Treponema pertenue
Treponema carateum
Treponema pallidum
Treponema endemicum
Microbiology
Bacteria
28237709-9df6-42bd-8dd7-050972c3d8e6
multi
In xerophthalmia classification X2 stage is -
xeraphthalmia:- *The most characteristic and specific signs of vitamin A deficiency are eye lesions. *These develop before the age of 2years. *The term xerophthalmia comprises all the occular manifestations of vitamin A deficiency. WHO classification (1982) *The new xerophthalmia classification is as follows: *XN Night...
2
Bitots spots
Corneal xerosis
Corneal ulceration
Corneal scar
Ophthalmology
Miscellaneous
4f9d8d15-8b2e-4744-8c4e-ae497ed34d27
single
Nasopharyngeal carcinoma presents as:
(b) Mass in neck(Ref. Cummings, 6th ed., 1425; Scott Brown, 8th ed., Vol 3; 97)Nearly 75% of patients of nasopharyngeal carcinoma present with painless cervical lymphadenopathy of mainly the upper deep cervical lymph node.
2
Epistaxis
Mass in neck
Headache
Nasal stuffiness
ENT
Pharynx
370cc6f4-40ea-4c09-b691-cb2708cfd3ae
single
For a new-born baby with squint surgery should be done at:
Ans. 3-4 years
1
3-4 years
Immediately
10-12 years
18-21 years
Ophthalmology
null
5aab0a2b-1160-48ef-8dd6-59272bcdd0e4
single
BA lady with abdominal mass was investigated. On surgery, she was found to have b/1 ovarian masses with smooth surface. On microscopy they revealed mucin secreting cells with signet ring shapes. What is your diagnosis?
Ans. (b) Krukenberg tumour(Ref: Robbin's Pathology 9th Ed/Pg 1032; Robbin's Pathology 8th ED/PG 1050; Shaw's Textbook of Gynaecology 15/e pg 425)Krukenberg Tumor*Refers to a metastatic bilateral ovarian malignancy whose primary site is GIT or breast. Q*Composed of cellular or myxomatous stroma with scattered mucin-prod...
2
Dysgerminoma
Krukenberg tumour
Primary Adenocarcinoma of the ovaries
Dermoid cyst
Pathology
Female Genital Tract
148150af-a43c-44e6-b23f-beadbf4aaa55
single
Which of the following types of shock will have high cardiac output
Distributive shock describes the pattern of cardiovascular responses characterising a variety of conditions including septic shock, anaphylaxis and spinal cord injury. Inadequate organ perfusion is accompanied by vascular dilatation with hypotension, low systemic vascular resistance, inadequate afterload and a resultin...
3
Hypovolemic
Cardiogenic
Distributive
Obstructive
Surgery
null
59e1fd37-c620-443e-8ed6-9d4d5d802fec
single
Intermediate metabolite in TCA cycle are A/E:
All of the above
4
Pvruvate
Malonate
Nitric oxide
All of the above
Biochemistry
null
f60f7ce4-aef8-4b1e-9414-8e84a1bdd8d9
multi
According to Ferriman Gallwey scoring system - hirsutism is diagnosed when score is more than :
Ferriman and Gallwey described scoring system in 9 body areas Scale of 0-4 Quantifies hair growth Score of > 8 is defined as hirsutism Ref: SHAW&;S TEXTBOOK OF GYNAECOLOGY; 15 TH EDITION; PG NO:115
1
8
12
16
20
Gynaecology & Obstetrics
PCOD, hirsutism and galactorrhea
d8def51b-aaab-4c5a-8245-59767180fe0d
multi
Vitamin for which RDA is based on protein intake is:
Ans. C. Pyridoxine(Ref: Harper 31/e page 533-540)The RDA of Pyridoxine is dependent on Protein intake.The RDA of Thiamine is dependent of Carbohydrate intake.
3
Niacin
Riboflavin
Pyridoxine
Thiamine
Biochemistry
Nutrition & Digestion
fbf72b80-20fc-414e-819b-72810e16bb61
single
Recent first line management of trigeminal neuralgia:
null
2
Peripheral neurectomy.
Anticonvulsant drugs'.
Radio-frequency ablation.
Diagnostic regional nerve block.
Pathology
null
3272bd7e-28ab-4d09-bf75-57fae1f628b2
single
A person has unprotected sex 3 weeks back. To rule out HIV infection the best test is-
Ans. is 'a' i.e., p24 antigen assay Laboratory diagnosis of HIV infectiono Laboratory diagnosis is made by :A) Antibody detection# It is the most common method used for diagnosis of HIV infection.# ELISA is the most sensitive test and therefore is the serening test of choice.# Western blot is the most specific (Confirm...
1
P24 antigen assay
ELISA
Western blot
Lymphnode biopsy
Microbiology
Human Immunodeficiency Virus
27ad86d1-13d2-4825-8d93-a817da245f02
single
Most common cause of genu valgum in children is ?
Ans. is 'b' i.e., Rickets o Genu valgum (also known as knock knee) is a condition where knees are abnormally approximated and ankles are abnormally divergent. o It is caused due to softening of bones or damage to lateral Femoral epiphysis Out of given options ? o Most common cause in children is Rickets. o Other diseas...
2
Osteoahritis
Rickets
Paget disease
Rheumatoid ahritis
Pediatrics
null
2aef1c4c-96ce-44f3-8168-bb1e3cabde49
single
The CFTR gene associated with cystic fibrosis is located on chromosome:
CFTR gene associated with cystic fibrosis is located on chromosome 7 In patients with cystic fibrosis blockage of the movement of ions and, therefore, water into and out of cells leads to the production of thick mucus. Absent vas deferens in males explains infeility in cystic fibrosis.
3
4
5
7
12
Medicine
Cystic fibrosis & Sleep apnea
9b3e9621-5c34-4484-9b2c-b582dec218e5
single
All of the following statements about Brown Sequard Synndromes are true, except:
Proprioception is lost on the same side of lesion in Brown Sequard syndrome. Brown sequard syndrome or hemisection of the cord is associated with loss of posterior column sensations (vibration, joiny position sense, proprioception, fine touch) on the same side of lesion. Sensations transmitted by the anterolateral colu...
2
Ipsilateral loss of power
Contralateral loss of Proprioception
Ipsilateral loss of Fine touch
Contralateral loss of pain
Physiology
Nervous system
14f6baf0-4d02-473b-83e9-2adbe37de7ff
multi
Chloroma is a tumor of -
null
3
Soft tissue
Bone
Hemopoeitic cell
Ovary
Pathology
null
2a96d259-5b20-40c8-aa0d-c56c8858e496
single
Arborescent burns are seen in: September 2009
Ans. B: Lightning stroke An almost pathognomonic cutaneous feature of lightning stroke is known as feathering/lightning prints/ Arborescent/ Filigree burns It comprises of linear, fernlike, superficial skin markings (also called keraunographic marks) that may disappear after 1-2 days. These cutaneous manifestations of ...
2
Flame burns
Lightning stroke
Heat stroke
Electrocution
Forensic Medicine
null
09ff6fb9-13ba-4ffe-8558-44e6e429e20c
single
Waldeyer's ring consists of all of the following except ?
Ans. is 'd' i.e., Posterior auricular nodes o In relation to the oropharyngeal isthmus, there are several aggregations of lymphoid tissue that constitute the WALDEYER'S lymphatic ring.o The most important aggregations are the right and left palatine tonsils,o Posteriorly and above is the pharyngeal tonsil,o Laterally a...
4
Palatine tonsils
Pharyngeal tonsils
Tubal tonsils
Post auricular nodes
Anatomy
Pharynx
3cb6692c-d094-4ffa-b7c8-0bf8e34b945c
multi
Leucocoria is seen in all except
In congenital glaucoma the cornea is white due to edema as a result of increased IOP, but Leucocoria is not seen . Refer khurana 6/e 415
2
Retinoblastoma
Congenital glaucoma
Persistent primary hyperplastic vitreous
Fungal Endophthalmities
Ophthalmology
Diseases of orbit, Lids and lacrimal apparatus
81619a4a-eba5-4754-a595-0fd3e78628e5
multi
Mean + 1.96 SD include following % of values in a distribution: September 2012
Ans: D i.e. 95% 96 is the approximate value of the 97.5 percentile point of the normal distribution used in probability and statistics. 95% of the area under a normal curve lies within roughly 1.96 standard detions of the mean, and due to the central limit theorem, this number is therefore used in the construction of a...
4
68%
99.50%
88.70%
95%
Social & Preventive Medicine
null
b46767bb-f06c-4ab9-b2df-a4da9beb680b
single
The compensation claim at State Level Dispute Redressal Commission is:
CONSUMER  PROTECTION  ACT (CPA/COPRA) The  Consumer  Protection  Act,  1986  that came  into  force  on  15th  April  1987  is  a  JOTG & milestone  in  the  history  of  socio-economic legislation in the country. It is one of the most progressive  and  comprehensive  piece  of legislations  enacted  for  the  protecti...
2
Less than 5 lakhs
5 - 20 lakhs
More than 20 lakhs
5-10 lakhs
Dental
null
5f939679-8859-4868-9bb2-fd2edba7cbab
single
A 19 year old young girl with previous history of repeated pain over medial canthus and chronic use of nasal decongestants, presented with abrupt onset of fever with chills & rigor, diplopia on lateral gaze, moderate proptosis & chemosis. On examination optic disc is congested. Most likely diagnosis is
Cavernous sinus thrombosis Repeated pain over medial canthus and chronic use of nasal decongestants suggest chronic ethmoidal sinusitis. Patient's other symptoms suggest that she has landed up in complicated sinusitis Now lets see the symptoms one by one ? There is sudden onset of ? - Chills & rigor Systemic symptoms -...
1
Cavernous sinus thrombosis
Orbital cell ulitis
Acute Ethmoidal sinusitis
Orbital apex syndrome
Ophthalmology
null
c1a43496-e8a7-4ccf-bbbf-d39622d40179
single
Trauma from occlusion refers to
null
3
Occlusion which causes trauma
Abnormally of the periodontium
Changes in periodontium due to occlusal forces
Inflammation of periodontium
Dental
null
6da1c665-afec-47a8-b601-c810e314c7b0
multi
Investigation of choice for invasive amebiasis is -
null
2
Indirect heamagglutination
ELISA
Counter immune electrophoresis
Microscopy
Medicine
null
f7d1afab-900e-41ff-953f-fc019063e6c7
single
A patient is unable to close her right eye. Physical examination reveals weakness of the right orbicularis oculi. Which of the following additional symptoms would likely also be present?
If the lesion affected the facial nerve more proximally, additional findings would be hyperacusis (increased sensitivity to sound because of stapedius muscle paralysis), lack of taste sensation in the anterior two-thirds of the tongue, and disturbed lacrimation and salivation.
2
Blurred vision
Hyperacusis
Inability to chew
Inability to feel the face
Anatomy
All India exam
7847d11f-5edc-4c24-8db1-9ff515264321
single
Space of Disse is in:
Ans. C. LiverThe perisinusoidal space (or space of Disse) is a location in the liver between a hepatocyte and a sinusoid. It contains the blood plasma.Microvilli of hepatocytes extend into this space, allowing proteins and other plasma components from the sinusoids to be absorbed by the hepatocytes.
3
Spleen
Lymph node
Liver
Bone
Anatomy
Histology
93108da3-8f9c-4314-a0b9-2f4a95904723
single
Venkataraman-Ramakrishnan media is used for: March 2005
Ans. C: Vibrio cholerae Transpo media for cholera vibrios are: Modified Cary and Blair medium is recommended as a good transpo medium. It is a very stable medium and can be stored for use in screw capped containers. It is a semi-solid transpo medium. At least two swabs should be inoculated. Alternative transpo media fo...
3
Sterptococcus pneumoniae
Staphylococcus aureus
Vibrio cholerae
Clostridium tetani
Microbiology
null
b09c6cfe-e244-445f-a2b1-037709f015b0
single
Protein requirement in adult male
Ref:Park's Textbook of Preventive and Social Medicine 25th Ed Pgno : 662
2
0.5 gm/kg/day
1 gm/kg/day
1.5 gm/kg/day
2 gm/kg/day
Social & Preventive Medicine
Nutrition and health
33c583e9-ea87-4662-b95a-7af179accedf
single
Straight back syndrome is associated with?
Straight back syndrome: Loss of thoracic kyphosis (antero-posterior diameter of chest is relatively lesser), so place available for hea is also less. Hea is sandwiched b/w thoracic veebrae, sternum and rib cage. Causes Mitral valve Prolapse =>Mid Systolic click Ankylosing spondylitis - AR condition
1
Mitral valve Prolapse
Ankylosing spondylitis
Osteopetrosis
Cor-triatriatum
Medicine
Valvular hea diseases
b0ead171-a045-4dd1-a3a0-570b022217cb
single
Investigation of choice to differentiate pericardial effusion and dilatation of hea:
Ans. Echocardiography
1
Echocardiography
Angio cardiography
MR!
CT
Radiology
null
e4bc7cfb-d25a-4a0c-a74f-ea586d5fea8f
single
All of the following are true regarding Phrygian cap of gallbladder, except?
Phrygian cap Congenital anomaly of the gallbladder Results from folding of the gallbladder fundus Resembles a soft conical cap with the top pulled forward Can simulate a mass in the liver during hepatobiliary imaging and is sometimes mistaken for pathology. Normally causes no symptoms Does not predispose to other disea...
2
Congenital anomaly of the gallbladder
Can lead to cholecystitis
Simulate a mass on radiological imaging
Results from infolding of the gallbladder fundus
Pathology
Miscellaneous
0a56e91f-e259-4d36-a506-22ffe2e32b4c
multi
Immediate stiffness postmoem occurs in -
Immediate rigor occurs in cadaveric spasm which is contraction of muscles during life which become stiff and rigid immediately after death. Dr. Narayana Reddys Synopsis of Forensic Medicine & Toxicology 27 th edition pg. 81.
2
Cadaveric rigidity
Cadaveric spasm
Rigor mois
Algor mois
Forensic Medicine
Death and postmortem changes
d43b0467-2d00-4b91-904a-ff2120f40454
single
A 12 year old boy presented with complaints of progressive head ache and visual disturbance which is not improved by any medical approaches. During evaluation CT scan of the head shows supracellar enlargement with calcification is seen. The diagnosis is?
In children Craniopharyngeoma presents as visual disturbance and growth failure. A craniopharyngioma is a slow-growing, extra-axial, epithelial-squamous, calcified, and cystic tumor arising from remnants of the craniopharyngeal duct and/or Rathke cleft and occupying the (supra) sellar region. Craniopharyngiomas most fr...
1
Craniopharyngeoma
Meningioma
Neurocysticercosis
Astrocytoma
Pediatrics
null
d67acf64-701a-48d1-96ca-10f5c614f098
single
All are used in the diagnosis of diabetes mellitus except:
C i.e. D-xylose absorption testGlycosylated hemoglobin (HbAic, an index of average glucose level in preceding 12 weeks), Fasting blood sugar (FBS 126 mg/dl), oral glucose tolerance test (OGTT) i.e. 2 hour post prandial glucose levels (> 200 mg/dl) and random blood sugar (RBS > 200 mg(dl) are used to diagnose diabetes m...
3
FBS
HbAlc
D-xylose absorption test
OGTT
Biochemistry
null
2337f0bf-2f4a-414e-bea2-a677d4e648f7
multi
All of the following clinicopathologic features are seen more often in seminomas as compared to nonseminomatous germ cell tumors of the testis except:
Answer is 'c' ie They are often associated with raised levels of serum AFP and HCG
3
They are radiosensitive
They metastasize predominantly by lymphatics
They are often associated with raised levels of serum AFP and HCG
All
Surgery
null
95f8c6ce-9d81-409e-9b8b-78096f40fd35
multi
HCN causes -
Hydrocyanic acid Cyanide occurs as solid, liquid or in gaseous state as: * Gas form -- Hydrogen cyanide (HCN) * Liquid form -- Hydrocyanic acid (Prussic acid) * Solid form -- occurs as salts such as potassium cyanide/ sodium cyanide. Mechanism of Action Cyanide reversibly inhibits ferric iron containing enzymes. Cyanid...
3
Histotoxic anoxia by inhibiting carbonic anhydrase
Histotoxic anoxia by inhibiting succinyl oxidase
Cytotoxic anoxia by inhibiting cytochrome oxidase
Cytotoxide anoxia by inhibiting succinyl oxidase
Forensic Medicine
Poisoning
b24b5ebb-d46d-480f-b80c-67732327ee1b
single
Cause of clostridium difficle associated diarrhea ?
Ans. is 'd' i.e., Antibiotic use
4
Trauma
Dairy products
Fried rice
Antibiotic use
Microbiology
null
fc913366-8a30-442c-9769-0e4aa0ad5829
single
All are the contraindications for vaginal birth after previous caesarean except:
Previous 2 LSCs and not a single one is a C/I for VBAC.
2
Previous classical uterine incision
Previous lower segment transverse caesarean
Presence of inverted 'T' shaped uterine incision
Where facilities for emergency caesareans are not available
Gynaecology & Obstetrics
null
6cf6e555-9990-44aa-9df5-954bceeac5e1
multi
In a chronic alcoholic patient all of the following drugs should be avoided except -
Ans. is 'd' i.e., Beclomethasone o The drugs causing Disulfiram like actions (i) Chlorpropramide (iv) Citrated calcium carbamide (vii) Griseofulvin (ii) Cephalosporins (Cefoperazone, (v) Cynamide (viii) Procarbazine moxalactam, cefamandole) (vi) Animal charcol (ix) Tinidazine (iii) Metronidazole
4
Cefamendole
Metronidazole
Chlorpropamide
Beclomethasone
Pharmacology
null
b0fd3907-e8ef-4713-ab24-0d3ff8cd9578
multi
Which of the following disease is not transmitted from animals to man
Ans: a (German measles)Ref: Park, 20th ed. Pg. 139German measles or rubella is an acute respiratory infection of childhood, characterized by low grade fever, lymphadenopathy, and a maculopapular rash. The disease is caused by a RNA virus, and is transmitted directly from person to person by droplets from nose and throa...
1
German measles
Rabies
Taenia solium
Plague
Social & Preventive Medicine
Communicable Diseases
a77a92d2-4c55-47f3-a1a7-899440956a12
single
Beaded margin of eyelid is seen in:
Lipoid proteinosis REF: http : //en. wikipedia org/wiki/U rbach%E2 %80%93Wiethe_disease "Urbach--Wiethe disease (also known as lipoid proteinosis and hyalinosis cutis et mucosae) is a rare autosomal-recessive disorderwith fewer than 300 repoed cases since its discovery, that presents in early childhood with hoarseness,...
4
Erythema granuloma annulare
Leprosy
Granuloma annulare
Lipoid proteinosis
Ophthalmology
null
b94a882a-aa02-4b22-b762-2703b093fa5e
single
Which hormone is responsible for acne -
Ans. is 'c' i.e., TestosteronePredisposing factors for Acne vulgariso Genetic factorso Hormones - Androgens, glucocorticoids,o Psychological stress and depression,o Environmental factors - High temperature & humidity,o Cosmetics - Containing lenolin, petroleum, vegetable oils,o Infection - Propionibacterium, Pityrospor...
3
Estrogen
Thyroid
Testosterone
Gonadotropins
Skin
Papulosquamous Disorders
433ca597-e680-44cd-a60a-614496d469bd
single
Sickle cell disease is present with which mutation:
Ans. (d) Base pair substitutionRef: Harper's Biochemistry, 30th ed. pg. 416-17A partial missense mutation (type of base pair substitution) glutamic acid, the normal amino acid in position 6 of the b chain, has been replaced by valine.
4
Cross-linked defect
Base pair defect
Mismatch defect
Base pair substitution
Biochemistry
Proteins and Amino Acids
640326f3-0a91-4542-bbfb-0b18fd9982a4
single
The best skin graft for open wounds is -
null
4
Isograft
Homograft
Allograft
Autograft
Surgery
null
5d9ce366-9197-4bd0-bff8-bdaa9c372b82
multi
Most common site of Ewing's sarcoma ?
Ans. is 'd' i.e., Shaft of femur Commonest site Ivory osteoma - Frontal sinus Osteoid osteoma - Tibia Admantinoma (Ameloblastoma) - Mandible Chordoma - Sacrum and cervical spine Osteoclastoma - Lower end of femur Ewing's sarcoma - Femur diaphysis > tibia diaphysis Osteosarcoma - Distal femur (45%), Proximal tibia (25%)...
4
Upper end of tibia
Shaft of tibia
Lower end of femur
Shaft of femur
Surgery
null
f5324d8b-64d4-4fbc-a040-cd60dd7cd4f0
single
Lymphoid malignancy arising from thymic cells are
About 85% are B -ALLs, which typically manifest as childhood acute leukemia. Less common T - ALLs tend to present in adolescent males or thymic lymphomas. These thymic lymphomas causes compression of large vessels and airway in the mediastinum.
4
Follicular lymphoma
Diffure large B-cell lymphoma
Burkitt lymphoma
Pre-Tcell All
Pathology
null
72ae59a1-59ab-400a-8532-d0f436b0e2ea
multi