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Beta oxidation of fatty acids occur in
Tissues in which bbb-Oxidation is carried out: The circulating FA are taken up by various tissues and oxidised. Tissues like liver, hea, kidney, muscle, brain, lungs, testes and adipose tissue have the ability to oxidise long-chain FA. In cardiac muscle, fatty acids are an impoant fuel of respiration (80% of energy der...
2
Nucleus
Mitochondria
Cytoplasm
Peroxisomes
Biochemistry
Metabolism of lipid
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single
Neurofibroma is -
Ans. is 'a' i.e., Autosomal dominanto Neurofibromatosis comprises of two distinct disorders -Neurofibromatosis INeurofibromatosis IIo The genes for these are located on different chromosomes,o Both are inherited in an autosomal dominant pattern.NF-1: Neurofibroma gene on chromosome 17.NF-2: Neurofibroma gene on chromos...
1
Autosomal dominant
Autosomal recessive
X-finked recessive
X-linked dominant
Unknown
null
d092e5ba-218a-44a3-894e-83efbc5f247f
single
Which of the following disease is associated with loss of the disc space and vertebral bone?
null
2
Multiple myeloma
Tuberculosis
Metastasis
Lymphoma
Surgery
null
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Staphylococcal capsule is made up of:
Ref: Ananthanarayan, Paniker CJ. Textbook of Microbiology. 6th Ed, London: John Wiley & Sons: 2000. & Prescott LM. Microbiology. 5th Ed. London: McGraw-Hill: 2002.Explanation:Capsules usually are composed of polysaccharides, but they may be constructed ot other materials.But, Bacillus anthracis has a capsule of poly-D-...
2
Hyaluronic acid
Polysaccharide
Polypeptide
Poly-D-glutamic acid
Microbiology
Staphylococci
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single
Lung abscess is least likely a complication of
Lung abscess can be divided on acute (less than 6 weeks) and chronic (more than 6 weeks). It can be called primary as a result of aspiration of oropharyngeal secretions (dental/periodontal infection, para nasal sinusitis, disturbance states of consciousness, swelling disorders, gastro-oesophageal reflux disease, freque...
2
Lobar pneumonia
Bronchopneumonia
Malignancy
Bronchiectasis
Medicine
Respiratory system
aae29d05-d901-46e9-8704-61e2fdbb0000
single
Kala-agar is transmitted by -
Ans. is 'b' i.e., Sandfly Diseases transmitted by sandflv Kala-azar Sand-fly fever o Oriental sore o Oraya fever
2
Reduvid bug
Sandfly
Tsetse fly
Mosquito
Social & Preventive Medicine
null
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single
According to Sigmund Freud, primary process thinking is -
Primary process (related to Id):- Unorganized & non-logical thinking. Secondary process (related to Ego):- Reality oriented, goal-directed, logical, rational, concrete and/or abstract conceptual thinking.
1
Illogical & Bizarre
Rational
Absent during sleep
Logical & unconscious
Psychiatry
null
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NOT a side effect of Lithium
(A) Leucopenia # RENAL: The renal side-effects occur in 10-50% of all patients on maintenance lithium therapy. Polyuria, polydipsia. Tubular changes. Nephrogenic diabetes insipidus. Nephrotic syndrome.> Gastrointestinal: These side-effects are nausea, vomiting, diarrhea, metallic taste and abdominal pain.> Dermatologic...
1
Leucopenia
Hypothyroidism
Polyuria
Hypercalcaemia
Psychiatry
Miscellaneous
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single
A diagnostic wax-up is indicated when _____.
It is recommended that any time there is a question regarding the treatment outcome involving a prosthetic device, or the need to produce templates for provisional restorations that reproduce a desired form of teeth, a diagnostic wax-up should be generated.
4
Re-establishing anterior guidance
A provisional fixed prosthesis is to be fabricated
Uncertainty exists regarding esthetics
All of the above
Dental
null
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multi
Occulomotor nerve palsy causes all of the following EXCEPT
Upward & lateral detion of eyeball doesn't happen in oculomotor nerve palsy. Oculomotor nerve (CN III) innervates all EOM except: Superior oblique (CN IV) & lateral rectus (CN VI) Paralysis of CN III results in: Ptosis (due to LPS involvement) Lateral & downward detion of eye (LR & SO are the only muscles intact, unopp...
3
Ptosis
Mydriasis
Upward and lateral detion of eyeball
Pupillary reflex lost
Anatomy
Eye, Nose and Ear
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multi
Extrinsic system (blood coagulation) is triggered by the release of: September 2008
Ans. B: Thromboplastin Factor X can be activated by reactions in either of two systems, an intrinsic and an extrinsic system. The extrinsic system is triggered by the release of tissue thromboplastin, a protein-phospholipid mixture that activates factor VII. The tissue thromboplastin and factor VII activate factors IX ...
2
Prothrombin
Thromboplastin
Fibrinogen
Thrombin
Physiology
null
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single
Second gas effect is seen with
The second gas effect is a distinct phenomenon that occurs independently of the concentration effect. The ability of the large-volume uptake of one gas (first gas) to accelerate the rate of increase of the Pa of a concurrently administered companion gas (second gas) is known as the second gas effect. For example, the i...
2
Ether
Nitrous oxide
Halothane
Isoflurane
Anaesthesia
General anaesthesia
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single
Pasteurization by Holder method is heating milk at
Methods of Pasteurization:
3
60° C for 45 minutes
100° C for 15 minutes
65° C for 30 minutes
136° C for 15 minutes
Social & Preventive Medicine
null
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single
Syneresis is associated with
null
1
Hydrocolloids
Elastomers
Zinc oxide eugenol
Plaster of paris
Dental
null
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single
Absence seizures are characterized on EEG by-
null
1
3 Hz spike & wave
1-2 Hz spike & wave
Generalized polyspikes
Hypsarrythmia
Medicine
null
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single
509-IPC deals with:
(Act intended to insult the modesty of a women)* Perjury (Giving false evidence) - 191-IPC* Criminal negligence - 304-A-IPC* Dowry deaths - 304 - B IPC* 509 IPC - word, gesture or act intended to insult the modesty of woman.* 510 IPC - Misconduct in public by a drunken person.* 376A - Intercourse by a man with his wife...
4
Masturbation in public place
Inquest
Dowry death
Act intended to insult the modesty of a women
Forensic Medicine
Law & Medicine, Identification, Autopsy & Burn
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single
Delirium is defined as ?
Ans. A. Acute onset of disturbed consciousnessDelirium is defined by the acute onset of fluctuating cognitive impairment and a disturbance of consciousness.It is also referred to as acute confusional state or acute organic brain syndrome.
1
Acute onset of disturbed consciousness
Chronic onset of disturbed consciousness
Progressive generalized impairment of intellectual functions and memory without impairment of consciousness
Disorientation without clouding of consciousness
Psychiatry
null
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The major ejection force in vomiting is provided by
The major ejection force in vomiting is provided by Abdominal muscles.
4
Stomach
Reverse peristalsis of intestine
Diaphragm
Abdominal muscles
Physiology
null
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single
Which of the following is an example of an ARCON type articulator?
null
4
Trubyte articulator
Dentatus, ARL articulator
Gysi articulator
None of the above
Dental
null
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multi
Respiratory distress is seen in
As both the cords lie in median or paramedian position, the airway is inadequate causing dyspnoea and stridor but the voice is good. Dyspnoea and stridor become worse on exeion or during an attack of acute laryngitis Ref: PL Dhingra Textbook of Ear, Nose and Throat, Edition 7, page - 339
1
Bilateral abductor palsy
Unilateral abductor palsy
Unilateral recurrent laryngeal nerve paralysis
null
ENT
Larynx
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Primary action of inferior oblique muscle is -
Ans. is 'c' i.e., Extorsion MusclePrimary ActionSecondary ActionSuperior rectusElevationAdduction and intorsionInferior rectusDepressionAdduction and extorsionMedial rectusAdduction Lateral rectusAbduction Superior obliqueIntorsionAbduction and depressionInferior obliqueExtorsionAbduction and elevation
3
Abduction
Adduction
Extorsion
Elevation
Anatomy
Orbit
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single
Pseudo koebener's phenomeneon is/are seen in – a. Warts b. Molluscum contagiosum c. Lichen planus d. Psoriasis
Pseudo-koebner's phenomenon is seen in plane wart, molluscum contagiosum and eczematous lesions.
1
ab
bc
cd
ad
Dental
null
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single
About NPCB, all are true except -
Ans. is 'c' i.e., 100% coverage of Vitamin A prophylaxis doses from 9 months to 3 years of age o Targets for tenth five year plan under national programme for control of Blindness (NPCB) were : - i) lb increase the cataract surgery rate to 450 operations per lakh population. ii.) Intra-ocular lens implantation in more ...
3
Increase cataract surgery rate to 450 operations per lakh population
Intra-ocular lens implantation in more than 80% cataract surgery cases
100% coverage of vitamin A prophylaxis doses from 9 months to 3 years of age
Development of 50 pediatric ophthalmic units
Social & Preventive Medicine
null
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multi
Pulp space infection painful due to?
Ans. is 'a' i.e., Dense fibrous septae Pulp space infection (felon) Pulp space infection with pus trapped between the specialised fingeip septae causes intense fingeip pain. It may lead to terminal phalangeal bone infection, erosion and sequestrumformation.The last of these will need to be drained and debrided. A commo...
1
Dense fibrous septae
Small phalynx
Rich blood supply
Rich nerve supply
Surgery
null
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multi
A 70 year old patient with history of smoking presents with gross painless hematuria. Likely diagnosis is
History of smoking, old age and gross hematuria it is likely to be bladder Ca.
2
Uerter stone
Ca. bladder
Ca. prostate
Bladder stone
Surgery
null
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single
Material of choice for incremental border moulding is:
Incremental or sectional border moulding: It is a procedure, in which portions of the periphery of the tray are refined individually. The material of choice for this procedure is green stick compound
2
Polyether
Greenstick compound.
Polysulphide
null
Dental
null
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multi
Acute phase reaction in acute inflammation are -
Infection or injury leads to a sudden increase in the plasma concentration of ceain proteins called acute-phase proteins. Acute phase reaction of acute inflammation albumin. REF:Textbook of microbiology, Ananthanarayan a, d Paniker. Page no.: 81
1
Albumin
Rfibrinogen
Haptoglobulin
Gammaglobulin
Microbiology
Immunology
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single
Zero dose of Polio vaccine in which is give -
null
2
Before giving DPT
At birth
When child is having diarrhoea
When child is having Polio
Social & Preventive Medicine
null
87367089-cf7a-4ef3-a49e-5ec6f11a0eb0
single
Branchial cleft anomalies are present at bih or sholy after bih. Which of the following is TRUE about branchial anomaly?
The usual course of branchial cleft apparatus anomalies is recurrent infection. These masses may present in the neck as a discrete fullness along the anterior border of the sternocleidomastoid. Cysts are more common than fistulas or sinuses. The majority of branchial cleft cysts arise from the second branchial cleft, w...
4
Fistulas are more common than cysts
For sinuses surgery is not always indicated
Cysts present with dysphagia and hoarseness of voice
Most commonly due to 2nd branchial remnants
Surgery
null
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Trichomonas -- which of the following true is ?
Discharge is thin greenish yellow,frothy offensive smelling profuse in nature vulva inflamed with evidence of pruritis PH is 5.5-6.5 D.C.DUTTA&;S TEXTBOOK OF GYNAECOLOGY,Pg no:164,6th edition
1
Foul smelling copious vaginal discharge
scanty discharge
curdy white discharge
fluconazole is used
Gynaecology & Obstetrics
Infections of the genital tract
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Unit of measurement of insulation of clothing is
Clothing insulation is the thermal insulation provided by clothing.Clothing insulation may be expressed in clo units1 Clo = 0.155 m2K/WClo = 0 - corresponds to a naked personClo = 1 - corresponds to the insulating value of clothing needed to maintain a person in comfo sitting at rest in a room at 21 (70 ) with air move...
2
Cl units
Clo Units
Clot units
Cloth units
Social & Preventive Medicine
Concept of health and disease
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single
A 15 year old child presents with falling school grades and development of abnormal posture. On examination dystonia and increase muscle tone is noted. Slit lamp examination shows presence of KF ring. Liver biopsy for copper will be stained by which of the following stain?
Rubeanic acid and Rhodamine stains are utilized to detect the cytoplasmic accumulation of copper in the liver. Schmorl's method is used for detecting melanin and uses the reducing propeies of melanin to stain granules blue-green. It is also used to detect lipofuscin.
2
Perl stain
Rubeanic acid
Supravital stain
Schmorl's method
Medicine
Wilson Disease
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multi
SEPS is used for
. SEPS-Subfascial Endoscopic Perforator Ligation Surgery,it us recommended in chronic venous insufficiency. procedure: A special telescope is introduced deep to deep fascia through a single small veical incision at proximal leg selecting healthy skin.potential space between muscle and deep fascia with loose areolar tis...
2
Aery
Veins
Lymphatics
Lymphnodes
Surgery
Vascular surgery
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The Fc piece of which immunoglobulin fixes C1 -
IgM is paicularly effective at complement activation by binding to C1 Ref: Ananthanarayan & Parker's textbook of microbiology 9th edition pf:98
3
IgA
IgG
IgM
IgE
Microbiology
Immunology
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The following is not an indication of this procedure:
Ans. (C). Wife is FrigidThe image shows artificial insemination procedure.It is the procedure of artificial introduction of semen into female genital tract to induce pregnancy.Indications of artificial insemination:Husband is impotentHusband is sterileHusband is unable to deposit semen due to hypospadiasisHusband is su...
3
Husband is impotent
Husband is sterile
Wife is frigid
Rh incompatibility between husband & wife
Forensic Medicine
Sexual Offenses
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single
Polyuria is feature of all of the following except -
null
1
Hypocalcemia
Hypokalemia
Lithium toxicity
ADH deficiency
Medicine
null
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Marker of small cell cancer of lung is -
Ref:Textbook of pathology (Harsh mohan) 6th edition,page no.500 Small cell carcinoma: Small cell carcinomas are frequently hilar or central in location, have strong relationship to cigarette smoking and are highly malignant tumours. They are most often associated with ectopic hormone production because of the presence ...
1
Chromogranin
Cytokeratin
Vimentin
Desmin
Pathology
Respiratory system
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multi
Leukotriene receptor antagonist used for bronchial asthma is:
Ans. (A) Zafirlukast(Ref: KDT 8th/e p248)Montelukast, zafirlukast and idalukast are Cys-LT1 receptor antagonists.Zileuton inhibits the production of leukotrienes by inhibiting the enzyme 5-lipoxygenase.
1
Zafirlukast
Zileuton
Cromolyn sodium
Aminophylline
Pharmacology
Asthma
77caf877-040d-461d-8e31-20d5bdc60dc0
single
Which of the following is NOT a side effect of amiodarone?
Ans. is 'd' i.e., Tachycardia * Amiodarone is a broad spectrum anti - arrhythmic drug which belongs to class III of the anti - arrhythmic drugs.* Following are the adverse effects -i) Fall in BP, bradycardia and myocardial depression occurs on i.v. injection.ii) Photosensitization and skin pigmentation occurs in about ...
4
Pulmonary fibrosis
Corneal microdeposits
Photosensitivity
Tachycardia
Pharmacology
C.V.S
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single
The mechanism of action of sodium nitroprusside is:
Ans. (B) Stimulation of guanylate cyclase(Ref: KDT 8th/e p544)Sodium nitroprusside acts by releasing nitric oxide (NO). This stimulates guanylate cyclase and results in the elevation of cGMP, which is a potent vasodilator.
2
Increased cAMP
Stimulation of guanylate cyclase
Calcium channel blockage
K+ channel opener
Pharmacology
C.V.S
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single
An infant has hepatorenomegaly, hypoglycemia, hyperlipidemia, acidosis and normal structured glycogen deposition in liver. What is the diagnosis ?
Ans. is 'b' i.e., Von Gierke's disease Von-Gierke disease (Type I glvcogenosis) o It is an autosomal recessive disorder. o It is due to absent or deficient activity of glucose-6-phosphatase in Liven Kidney, Intestinal mucosa o It can be divided into two subtypes ? i) Type Ia glucose - 6 - phosphatase is defective ii) T...
2
Her's disease
Von Gierke's disease
Cori's disease
Anderson's disease
Pediatrics
null
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Phagocytosis is the function of-
Ans is 'c' i.e., Microglia o Micro-organisms entering the tissue fluid or blood stream are very rapidly engulfed by the cells called phagocytes,o Phagocytic cells are of two types :o Basophils also belong to polymorphonuclear microphages but they are not phagocytes.o Eosinophils have only a limited degree of phagocytic...
3
Astrocytes
Oligodendrocytes
Microglia
Schawan cells
Pathology
Acute Inflammation - Overview and Morphologic Patterns
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single
Central dot sign is seen in?
Ans is c i.e. Caroli's disease Caroli's disease is a rare congenital abnormality in which there is communicating cavernous ectasia of the intrahepatic biliary ducts. Caroli's disease is equivalent to type V choledochal cyst. It is commonly associated with congenital hepatic fibrosis and cystic lesions of the kidney.Pat...
3
Primary sclerosing cholangitis
Liver Hamaoma
Caroli's disease
Polycystic liver disease
Surgery
null
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single
Which of the following is not the branch of maxillary branch of external carotid aery?
Maxillary aery is the larger terminal branch of the external carotid aery, given off behind the neck of mandible. It has three pasmandibular paPterygoid paPterygopalatine paBranches of respective pas are:Mandibular- deep auricular, anterior tympanic, Middle meningeal, accessory meningeal, Inferior alveolarPterygoid- ma...
4
Inferior alveolar
Middle meningeal
Anterior tympanic
Posterior tympanic
Anatomy
Brain
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single
A young patient presents with enlargement of the costochondral junction and with the white line of Fraenkel at the metaphysis. The diagnosis is -
Enlargement of the costochondral junction (rosary) and white line of Frankel are seen both in scurvy and rickets. However, the best answer here is scurvy as white line Fraenkel is seen in healing rickets, not in active rickets. And rickets (if not specified as healing rickets) refers to active disease.
1
Scruvy
Rickets
Hyperparathyroidism
Osteomalacia
Orthopaedics
null
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single
Halo effect in an X-Ray is seen in which condition
Halo effect is typical of vertical root fracture. As that is not in the option next best choice is periapical periosteitis
4
Horizontal Root Fracture
Acute apical abscess
Acute apical periodontitis
periapical periosteitis
Dental
null
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single
Thalamus is the sensory relay station for all except
Thalamus messages sensory relay station for all the senses Ref: guyton and hall textbook of medical physiology 12 edition page number: 691,692,693
4
Pain
Fine touch
Taste
All
Physiology
Nervous system
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multi
Stimulation of the nerves of the pelvic parasympathetic plexus results in
(A) Penile erection # PELVIC SPLANCHNIC NERVES or NERVI ERIGENTES are splanchnic nerves that arise from sacral spinal nerves S2, S3, S4 to provide parasympathetic innervation to the hindgut.> Structure: The pelvic splanchnic nerves arise from the ventral rami of the S2-S4 and enter the sacral plexus. They travel to the...
1
Penile erection
Constriction of the internal urethral sphincter
Vasoconstriction
Contraction of the genital smooth muscle
Physiology
Misc.
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single
Which is the primary gland responsible for thermoregulatory sweating in humans?
Human sweat glands are generally divided into two types: apocrine and eccrine. The eccrine gland is the primary gland responsible for thermoregulatory sweating in humans. Eccrine sweat glands are distributed over nearly the entire body surface. Apocrine glands are located only in genital, axillary and mammary areas. Re...
2
Apocrine gland
Eccrine gland
Sebaceous gland
Holocrine gland
Skin
null
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single
Platelet adhesion to vessel wall is due to?
Ans. (c) vWF(Ref: Robbins 9th/pg 660; 8th/pg 670)Platelet adhesion to vessel wall is due to vWF on endothelium and GpIb/IX receptors on the surface of platelets.
3
Factor IX
Fibrinogen
vWF
Fibronectin
Pathology
Bleeding Disorders
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Which is not true about hallucination
The hallucination is defined as perception without a stimulus. hallucination is experienced clear and vivid like a true perception it is not under the control of the person experiencing it and it seems to come from an external objective space for example, from outside the ears in the case of an auditory hallucination, ...
2
It is vivid as normal stimulus
It occurs in inner subjective space
It is independent of will of observer
It occurs in absence of perceptual stimuli
Psychiatry
Symptoms and signs in psychiatry and classification
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A case of spontaneous pneumothorax comes to you. What will be the earliest t/t of choice -
Pneumothorax: is the presence of gas in the pleural space. Types : (a) Spontaneous pheumothorax → is one that occurs without antecedent trauma to the thorax (i) Primary spontaneous - Occurs in the absence of an underlying lung disease (usually d/t apical plural blebs). (ii) Secondary spontaneous - d/t an underlying l...
2
IPPV
Needle aspiration
ICD
Wait and watch
Surgery
null
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single
Chief advantage of sanitary pontic is
null
3
Economical
Easy to fabricate
Easy to keep oral hygiene
All of the above
Dental
null
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multi
Primary closure of incised wounds must be done within
• Primary suture: −− Clean wounds −− Selected contaminated wounds after thorough wound toileting and debridement • Delayed primary suture: −− Heavily contaminated wounds −− Wounds in which wound toileting has been delayed for 6–8 hours • Left open to heal by secondary closure
3
2 hrs
4 hrs
6 hrs
12 hrs
Surgery
null
1ef4bec0-4ec4-47a8-b2f7-bd1d6473d92c
single
What will be the initial management in a hemodynamically stable patient with an anterior abdominal stab injury presenting with a tag of omentum protruding through the abdominal wall near the umbilicus and showing no signs of peritonitis?
emodynamically Stable patients with omental protrusion should be investigated thoroughly first with an abdomino-pelvic contrast enhanced CT scan, before proceeding to surgery. Exploratory Laparotomy is not an absolute indication for this case. Ref: Reference: Trauma: A Comprehensive Emergency Medicine Approach By Eric ...
2
FAST
CECT Abdomen
Exploratory Laparotomy
Local Wound Exploration and Suturing
Surgery
null
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Which of the following is not true about dengue shock syndrome?
Ans. is 'b' i.e., Well-nourished child is protected from the manifestation * The induction of vascular permeability and shock in dengue patients i. e. development of dengue shock syndrome depends on multiple factors, including the following:i) Presence of enhancing and nonneutralizing antibodies-- Transplacental matern...
2
Susceptibility to dengue shock syndrome drops considerably after 12 years of age
Well-nourished child is protected from the manifestation
Serotype 1 infection followed by serotype 2 seems to be more dangerous than serotype 4 followed by serotype 2
Serotype 2 infection has more chances of developing dengue shock syndrome compared to other serotypes
Medicine
Infection
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multi
All are factors of poor wound healing except -
Answer- A. Young ageSystemic factorsPoor nutrition (protein deficiency, vitamin C deficiency)Metabolic abnormalities (Diabetes mellitus).Poor circulatory status (Inadequate blood supply)Hormones, e.g. glucocoicoidsB. Local factorsInfection is the single most impoant factor.Mechanical factors, e.g. early mobilization.Fo...
1
Young age
Infection
Zinc deficiency
Vitamin D deficiency
Pathology
null
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multi
Transmission of R factor is by ?
Ans. is 'a' i.e., Conjugation Conjugation Bacterial conjugation is the transfer of genetic material between bacteria through direct cell to cell contact or through a bridge- like connection between two cells. Conjugation is process where by a donor (male) bacterium makes physical contact with a recipient (female) bacte...
1
Conjugation
Transduction
Transformation
Lysogenic conversion
Microbiology
null
4ee4f0e2-344f-4e2d-ae20-893589fa348b
single
Abtacept is used in treatment of which of the following conditions?
Abatacept is a recombinant fusion protein composed of the extracellular domain of cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) fused to human IgG Fc. CTLA-4 is a costimulatory molecule found on T cells that binds to CD80 and CD86 on antigen presenting cells. This fusion protein blocks activation of T cells by b...
1
Rheumatoid ahritis
Asthma
Paroxysmal nocturnal hemoglobinuria
Autoimmune haemolytic anemia
Pharmacology
null
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single
All of the following are watersoluble radical trapping antioxidants except?
Ascorbate, uric acid, and a variety of polyphenols derived from plant foods act as water-soluble radical trapping antioxidants. Ubiquinone and carotenes similarly act as lipid-soluble radical-trapping antioxidants in membranes and plasma lipoproteins. Reference: Harpers illustrated biochemistry 30th edition
2
Ascorbate
Carotenes
uric acid
Polyphenols
Biochemistry
vitamins
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multi
An enzyme involved in the catabolism of fructose to pyruvate in the liver is:
A i.e. Glyceraldehyde- 3- phosphate dehydrogenase
1
Glyceraldehyde-3-phosphate Dehydrogenase
Phosphoglucomutase
Lacta te-dehydrogena se
Glucokinase
Biochemistry
null
6fedf6a1-fdd2-4c23-9713-4a7d619de917
single
Which of the following changes would be most consistent with the diagnosis of choriocarcinoma?
Gestational trophoblastic disease may involve hydatidiform mole, choriocarcinoma, or placental trophoblastic tumor. Trophoblastic tissue produces B-HCG and thus B-HCG is elevated in all these conditions. AFP is increased in neural tube defect setting when screening at 15-18 weeks gestation. AFP may be decreased in Down...
1
Increased B-HCG
Increased alpha-fetoprotein (AFP)
Increased thyroid-stimulating hormone (TSH)
Decreased AFP
Surgery
Urethra & Penis
35544c59-a9ec-420f-af14-ea951bcf6e5c
single
Effectiveness of blood brain barrier is by:
A i.e. Tight endothelial function
1
Tight endothelial function
Microglial cell
Thick basement membrane
Tight arrangement of astrocyfes
Physiology
null
db5dde9f-3c4e-4169-8c02-d924df19e9a4
single
Which is not an epidemiological method of population survey?
null
1
Twin studies
Ecological studies
Correlational studies
Community trials
Dental
null
8c3ee1de-5215-4de3-b4cb-b6da8370b3a7
single
Confirmation of the diagnosis of vesicular mole is by :
Ultrasonogram
4
Vaginal examination
X-rays
Abdominal examination
Ultrasonogram
Gynaecology & Obstetrics
null
2909e917-e2f9-40ad-938d-40358104c2b3
single
A 90-year-old woman with mild diabetes and Alzheimer disease dies in her sleep. At autopsy, hepatocytes are noted to contain golden cytoplasmic granules that do not stain with Prussian blue. Which of the following best accounts for pigment accumulation in the liver of this patient?
Advanced age. Substances that cannot be metabolized accumulate in cells. Examples include (1) endogenous substrates that are not processed because a key enzyme is missing (lysosomal storage diseases), (2) insoluble endogenous pigments (lipofuscin and melanin), and (3) exogenous particulates (silica and carbon). Lipofus...
1
Advanced age
Alzheimer disease
Congestive heart failure
Diabetic ketoacidosis
Pathology
Cellular Pathology
0119fec0-c567-4783-b5e6-a8e693b28399
single
Primary biliary cirrhosis is most commonly associated with______
Primary Biliary Cirrhosis Autoimmune disorder Clinical manifestation - obstructive jaundice F > M Antibody seen in antimitochondrial ab which is formed against E2 subunit of PDH enzyme. Interlobular bile ducts are actively destroyed by lymphoplasmacytic inflammation with or without granulomas.
2
Systemic sclerosis
Sjogren syndrome
Ulcerative colitis
Pancreatitis
Pathology
Bilirubin Metabolism
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single
In apoptosis which is/are involved -
Ans. is 'a' i.e., Apaf-1; 'b' i.e., BCl2; 'c' i.e., Caspases
4
Apaf-1
Bc12
Caspases
All
Pathology
null
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multi
All of the following statements about the differences between self-polymerizing acrylic resins and heat—cured resins are true EXCEPT
null
4
The former have a lower molecular weight
The former have higher residual monomer content
The former are more porous
The former have greater transverse strength
Dental
null
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multi
All the following are the indicators for single visit endodontics EXCEPT
null
1
Acute inflammation of the periapex
Nonvital teeth with sinus tract
Vital tooth
Fractured tooth
Dental
null
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multi
All of the following are derivatives of connective tissue except?
null
2
Endothelial cells
Clara cells
Fibroblast
Mast cells
Anatomy
null
79d78906-e470-4c70-93ce-96299aa97942
multi
Taste fibres are relayed to which of the following structure?
Nucleus solitarius is an elongated sensory nucleus in the medulla that receives axons from cranial nerves VII, IX, and X. The rostral pa of this nucleus is called gustatory nucleus and it conveys information about taste and visceral sensations. Fibers from this nucleus ascend to ventroposterior nucleus (VPM) in the tha...
2
Nucleus of fifth nerve
Tractus solitarius
Nucleus ambiguus
Red nucleus
Anatomy
null
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single
Cause of ITP is
null
3
Vasculitis
Antibody to vascular epithelium
Antibody to platelets
Antibody to clotting factors
Medicine
null
a3fdca60-32bc-42af-9b25-2b227a121f6f
single
Most common location of accessory spleen?
Accessory spleen may be found at :- i) Hilum of spleen (most common site). ii) Tail of pancrease. iii) Derivatives of dorsal mesogastrium :- Greater omentum, gastrophrenic ligament, gastrosplenic ligament, linorenal ligament. iv) Broad ligament of uterus (in males) and spermatic cord (in female); both left side.
1
Hilum of spleen
Greater omentum
Lesser omentum
null
Anatomy
null
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multi
Standard in perimetry is
Goldmann's perimeter: It consists of a hemispherical dome. Its main advantage over the tangent screen is that the test conditions and the intensity of the target are always the same. It permits greater reproducibility, Goldmann perimeter stimuli I through V. Unless otherwise instructed, the equivalent to Goldmann size ...
3
Goldman type I
Goldman type II
Goldman type III
Goldman type IV
Ophthalmology
Anatomy, Development and clinical examination
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single
Filarial stage of adult worms responsible for diseases in all of the following except:
Ans. (d) Mansonella ozzardi Mansonella Ozzardi M. ozzardi is a new world filaria seen only in central and south America and the West Indies. The adult worms live in the body cavities of humans, mainly in peritoneum, less often in pleura, and rarely in pericardium. The microfilariae are unsheathed and nonperiodic. Vecto...
4
Onchocerca volvulus
Brugia
Wuchereria
Mansonella ozzardi
Microbiology
null
076e6f8c-23b7-4cdf-bbab-dac6a41646fc
multi
The rate of newly synthesized osteoid mineralization can be best estimated by -
Tetracycline labelling for osteoid mineralization Tetracycline labelling is the method of choice for estimating newly synthesized osteoid mineralization in human. Tetracycline is incorporated into new areas of osteoid that are being laid down but not yet mineralized (osteoid seams) To estimate the rate of newly synthe...
1
Tetracycline labeling
Alizarin red stain
Calcein stain
Van kossa stain
Orthopaedics
null
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single
In Complete cleft the hard palate is totally separated from?
Vomer REF: With text Palate cleft can occur as complete (soft and hard palate, possibly including a gap in the jaw) or incomplete (a 'hole' in the roof of the mouth, usually as a cleft soft palate). Normally the hard palate is continuous in front and laterally with the alveolar processes of the maxilla, and gives attac...
3
Maxilla
Soft palate
Vomer
All
Surgery
null
74403f60-1ba1-4fe8-808f-ff893ff86d6f
multi
Which of the following is the primary mechanism of action of fluoride on topical application?
The presence of fluoride reduces the solubility of enamel by promoting the precipitation of hydroxyapatite and phosphate mineral. Ca10(P04)6(OH)2 +2F- -> Ca10(PO4)6F2 + 2OH (OH ions are replaced) (hydroxy-apatite) (fluro-apatite) Ref: Essentials of Pedodontics By Tilakraj, Pages 182-3 ; A Textbook of Public Health Dent...
4
Forming a reservoir in saliva
Inhibition of plaque bacteria
Improvement in tooth morphology
Conversion of hydroxyapatite to fluorapatite by replacing the OH- ions
Pharmacology
null
3f02aa5a-3168-441a-8068-39a7941ff04f
single
A 2-year-old girl with a history of chronic constipation since birth is brought to the emergency room because of nausea and vomiting. Physical examination shows marked abdominal distension. Abdominal radiography reveals distended bowel loops with a paucity of air in the rectum. A rectal biopsy shows an absence of gangl...
Hirschsprung disease, also referred to as congenital megacolon, results from a congenital defect in the innervation of the large intestine, usually in the rectum. Severe chronic constipation is typical. Marked dilation of the colon occurs proximal to the stenotic rectum, with clinical signs of intestinal obstruction. T...
3
Acquired megacolon
Anorectal stenosis
Hirschsprung disease
Imperforate anus
Pathology
G.I.T.
0262524f-7df5-4d0d-a1a9-dcc691208a75
single
Reduviid bug is a vector for the transmission of -
bite by reduviid bug T.cruzi causes South American trypanosomiasis or chaga's disease Chagoma Romana's sign (refer pgno:50 baveja 3 rd edition)
4
Relapsing fever
Lyme's disease
Scrub typhus
Chaga's disease
Microbiology
parasitology
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single
Alpha granules of platelets contain all Except
Alpha granules contain P.Selectin, Fibrinogen, Coagulation factor V, VWF, Fibronectin, Platelet factor 4, PDGF, TGF bDelta granules contains ADP, ATP, ionized Ca, Serotonin, EpinephrineReference: Robbins and Cotran Pathologic Basis of Disease; 9th edition; Volume I; Page no: 117
4
Fibronectin
Platelet factor-4
Platelet-derived growth factor
Serotonin
Pathology
Haematology
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multi
Zafirlukast acts by blocking the action of :
null
4
Prostacyclin
Platelet activating factor
Leukotriene B4
Leukotriene C4/D4
Pharmacology
null
3a799a02-ef0c-4216-9fee-b2b34246f483
single
Plasmacytoid lymphomas may be associated with -
Plasmacytoid lymphoma Plasmacytoid lymphoma, also known as plasmacytoid lymphocyte type malignant lymphoma, is a B cell neoplasm that is associated with plasmacytoid differentiation of lymphocytes. Plasmacytoid lymphocytes are transitional forms between lymphocytes and plasma cells. These are low grade lymphoid neopla...
2
IgG
IgM
IgA
IgE
Pathology
null
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single
One gram of hemoglobin contains how muchiron ?
Ans. is 'b' i.e., 3.4 mgOne gram of hemoglobin contains 3.34 mg of iron.Normally, 100 ml of blood contains 15 gm of hemoglobin and about 50 mg of iron (3.34 15).So, if 100 ml of blood is lost from the body, there is a loss of about 50 mg of iron.In females, during every menstural cycle, about 50 ml of blood is lost by ...
2
2 mg
3.4 mg
5 mg
6 mg
Biochemistry
null
16128618-7cfc-46c6-a29d-dc392fe1e32d
single
Cataplexy is characterized by?
Ans. is 'c' i.e., Decreased muscle tone * Cataplexy is the most common accessory symptom of Narcolepsy and is characterized by sudden decrease in muscle tone, either, local or generalized.
3
Hypnopompic hallucinations
Nocturnal penile tumescence
Decreased muscle tone
Somnambulism
Psychiatry
Sleep Disorders
34d688d3-4d01-4283-bfd9-ee2bb0df1211
multi
What is the commonest site of esophageal carcinoma ?
The lower end of the oesophagus is also prone to inflammation or ulceration by regurgitation of acid from the stomach. It is the commonest site of oesophageal carcinoma. Ref : B D Chaurasia's Human Anatomy , seventh edition , volume 2 , pg.no.,273.
1
lower end of oesophagus
upper end of oesophagus
middle third of oesophagus
thorasic pa of oesophagus
Anatomy
Abdomen and pelvis
4ffc16f5-2438-4a2f-b9bd-82ae57347b1a
single
All are related to criminal responsibility of insame except ?
Ans. is 'd' i.e., Resp ispa loquitar
4
Currens rule
Durhan rule
Mc Naughten rule
Resp ispa loquitar
Forensic Medicine
null
1b839805-604e-40df-9dec-ebbbc468a346
multi
Each gram of fat supplies how many kcal of energy:
The various nutrients provide energy as follows: Nutrient Energy in kcal/ gram Protein 4 Carbohydrate 4 Fat 9 Dietary Fibres 2 Ref: Park 21st Edition, Page 585.
2
5
9
12
13
Social & Preventive Medicine
null
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single
Human Development Index includes all of the following except: March 2009, September 2009, September 2012, March 2013 (a, c, d, f)
Ans. A: Infant moality The Human Development Index (HDI) is a composite statistic used to rank countries by level of "human development" and separate developed (high development), developing (middle development), and underdeveloped (low development) countries. The statistic is composed from data on Life Expectancy, Edu...
1
Infant moality
Income
literacy rate
Life expectancy at bih
Social & Preventive Medicine
null
467b48f3-af28-4445-95c9-06a4e2d59420
multi
Vector of kala-azar is:
Leishmaniasis is caused by protozoan parasites belonging to the genus Leishmania.  The parasites are transmitted by the bite of a tiny – only 2–3 mm long – insect vector, the phlebotomine sandfly. There are some 500 known phlebotomine species, but only about 30 have been found to transmit leishmaniasis.  Only the femal...
1
Sandfly
Tsetse fly.
Mites
Flea
Microbiology
null
33bf8a61-fd14-4ee2-ba5b-29f12ea2a27c
single
Familial hypercholesterolemia is due to defect in
Name Defect Remarks Familial hypercholesterolemia (type IIa) Defective LDL receptors or mutation in the ligand region of apo B-100 Elevated LDL levels and hypercholesterolemia, resulting in atherosclerosis and coronary disease Reference: Harper; 30th edition; Page no: 275
4
Apo A
Lipoprotein lipase
Apo C
Apo B 100
Biochemistry
Metabolism of lipid
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single
Sacrotuberous ligament is not pierced by
Sacrotuberous ligament is pierced by Coccygeal branch of Inferior gluteal nerve Perforating cutaneous nerves Filaments of Coccygeal plexus
3
Coccygeal branch of Inferior gluteal nerve
Perforating cutaneous nerves
Posterior cutaneous nerve of thigh
Filaments of Coccygeal plexus
Anatomy
null
017b7329-89d5-4bf7-a501-63fc4e13f8ae
single
Black tongue is seen in abuse of:
D i.e. Cocaine
4
Heroine
Dhatura
Smoking
Cocaine
Forensic Medicine
null
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single
All of the following are TRUE about amoebic liver abscess, EXCEPT:
"Male preponderance of greater than 10:1 has been repoed in all studies" "A recent retrospective study comparing surgical with percutaneous drainage for large (>5 cm) abscess showed a better success rate with surgical drainage" "Percutaneous drainage of multiple abscess is usually met with a higher failure rate" "Like ...
2
Metronidazole is the mainstay of treatment
Shows male preponderance of 4:1
More common on right liver
Multifocal abscess cannot be treated with aspiration
Surgery
null
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multi
Intermittent painless uterine contractions which the mother is unaware, from 4th month of pregnancy is termed as
Braxton-Hick's sign The intermittent painless uterine contractions, occur once in 10-15 minutes, of which the woman is unaware. This can be felt on abdominal palpation from 4th month onwards. It is present even when the fetus is dead. Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 330
4
Jacquemier's sign
Quickening
Palmer's sign
Braxton Hick's sign
Anatomy
Miscellaneous
7537a27d-b7bc-4e96-b286-6425cba16d94
single
When Class III elastics are used, the maxillary first molars will:
Class III elastics are worn from the maxillary first molars to the mandibular canines. The force system created by Class III elastics will produce mesial movement and extrusion of the maxillary first molars.
2
Move distally and intrude
Move mesially and extrude
Move mesially and intrude
Move only mesially; there will be no movement in the vertical direction
Dental
null
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multi
Non-motile organism:
Ans. d. Antigenic
4
E. coli
Vibrio cholera
Protein in nature
Antigenic
Microbiology
null
9a0b4432-af7a-4765-85da-f36ac9ad580c
single
Which antineoplastic agent is an antifolate drug ?
Ans. is 'a' i.e., Methotrexate
1
Methotrexate
Adriamycin
Vincristine
Cyclophosphamide
Pharmacology
null
019f722e-2b58-4cbd-ae88-a38c1a7efd34
single
Paraneoplastic syndrome Hypercalcemia of malignancy, is produced due to ectopic production of which hormone by lymphomas ?
Ans. is 'b' i.e., 1, 25 dihydroxyvitamin D
2
PTHrP
1,25 dihydroxyvitamin D
PGE2
Parathormone
Pathology
null
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single