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Hydrogen peroxide is conveed to water and oxygen by enzyme?
Catalase, present in peroxisomes, catalyzes the decomposition of hydrogen peroxide (2H2O2 - O2 + 2H2O). Glutathione (GSH) peroxidases are a family of enzymes whose major function is to protect cells from oxidative damage 2 GSH (glutathione) + H2O2 - GS-SG + 2 H2O. myeloperoxidase conves H2O2 to a highly reactive compou...
2
Superoxide dismutase
Catalase
Glutathione peroxidase
Myeloperoxidase
Pathology
General pathology
cab538a9-e414-4761-abf5-4217342c10b5
single
Hypercalciuria is seen in:
Answer is D (All of the above): Hypercakiuria may be associated with Vitamin D intoxication (hypervitaminosis D), Sarcoidosis and hyperparathyroidism. Causes of Hypercalciuria-associated Nephrolithiasis in Children and Adults Idiopathic hypercalciuria Increased intestinal calcium absorption - Granulomatous disease e.g....
4
Hyperparathyroidism
Vit. D intoxication
Sarcoidosis
All
Medicine
null
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multi
Schneider's Ist rank symptoms seen in:
D i.e. Schizophrenia
4
Delusion
Hallusination
Schizoid personality
Schizophrenia
Psychiatry
null
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multi
Killian's dehiscence is seen in -
Between these two parts of inferior constrictor exists a potential gap called Killian's dehiscence. It is also called the gateway to tear as perforation can occur at this site during esophagoscopy. It is also the site for herniation of pharyngeal mucosa in case of the pharyngeal pouch.
3
Oropharynx
Nasopharynx
Cricopharynx
Vocal cords
ENT
null
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single
Hypsarrythmia in a child is due to-
Ans. is 'c' i.e., Myoclonic epilepsy Myoclonic epilepsy may be ? i) Infantile spasm or Infantile myoclonus or west syndrome ii) Juvenile myoclonic epilepsy Infantile spasm (Infantile myoclonus or west syndrome) o The onset is usually between 3-8 months of life o It is characterized by triad of ? i) Salaam spells (sudde...
3
Grandmal epilepsy
Petitmal epilepsy
Myoclonic epilepsy
Reflex epilepsy
Pediatrics
null
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single
All of the following are adverse effects of thalidomide except :
Thalidomide was banned because of teratogenic effects (phocomelia). Now it has come again in the market for use as an anticancer drug in multiple myeloma and melanoma. Lenalidomide is its more potent and non-teratogenic derivative. Thalidomide most commonly causes sedation and constipation in cancer patients. It can al...
1
Myocarditis
Constipation
Peripheral neuropathy
Sedation
Pharmacology
null
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multi
Neurotoxin is which snake -
Ans. is 'b' i.e., Krait Type of poisoningSnakeVasculotoxicVipersMyotoxicSea snakesNeurotoxicElapids- cobra, Krait, coral
2
Viper
Krait
Sea snake
null
Forensic Medicine
Forensic Toxicology - Concepts, Statutes, Evidence, and Techniques
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multi
Single gene defect causing multiple unrelated problems is called?
Pleotropism refers to single gene defect causing multiple traits. Penetrance- extent to which a paicular gene or set of genes is expressed in the phenotypes of individuals carrying it Pseudodominance- sudden appearance of a recessive phenotype in a pedigree, due to deletion of a masking dominant gene Anticipation- dise...
1
Pleiotropism
Pseudodominance
Penetrance
Anticipation
Pediatrics
Types of Genetic Disorders
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Urinary bacterial count of 105 is insignificant, in the absence of symptoms, in all of the following conditions except -
Significant growth of a Uropathogen in the absence of symptoms is termed Asymptomatic bacteriuria. Urinary bacterial count of 105 is significant in Pregnancy. Pathogens associated with UTI most commonly in pregnancy are most commonly E coli, along with Klebsiella, proteus, enterobacter, staphylococcus saprophyticus. Si...
1
Pregnancy
Healthy ambulatory male
In a setting of antibiotics treatment
Mid stream clean catch sample.
Gynaecology & Obstetrics
Medical Illness Complicating Pregnancy
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multi
Elastomers are
According to Chemistry Chemically, there are four kinds of elastomers: Polysulfide Condensation polymerizing silicones Addition polymerizing silicones Polyether
3
Alginate
Agar
Polyethers
Impression compound
Dental
null
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single
Cotton fever is due to the abuse of:
COTTON FEVER : Fever developing due to injection of a water extract of the cotton remaining after the heroin supply is used in a "bag"
2
Amphetamine
Heroin
Phencylidine
Cocaine
Forensic Medicine
Drug Abuse
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single
What causes both destruction of bone and reduction of joint space?
(a)TB in spine involves- 2 Vertebra (Bone) + Disk (Cartilage)- Paradiscal- Anterior (to spinal cord)Note: Involvement of posterior elements and single vertebra is relatively rare in TB.
1
Tuberculosis
Metastasis
Multiple myeloma
Lymphoma
Orthopaedics
TB of the Spine
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multi
The commonest malignant tumour of the lids is
MALIGNANT TUMOURS Basal-cell carcinoma It is the commonest malignant tumour of the lids (90%) usually seen in elderly people. It is locally malignant and involves most commonly lower lid (50%) followed by medial canthus (25%), upper lid (10-15%) and outer canthus (5-10%). Clinical features: It may present in four forms...
1
Basal-cell carcinoma
Squamous cell carcinoma
Adenocarcinoma
Melanocarcinoma
Ophthalmology
Tumors
3291e548-1e25-4fd4-9ae5-4405781ba419
single
How much fraction of methyl mercury is absorbed from the Gut:
null
4
20%
50%
80%
100%
Dental
null
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single
Point B in the treatment of carcinoma cervix receives the following dose of:
Two important points in the radiotherapy of cancer cervix are
2
7000 cGy
6000 cGy
5000 cGy
10,000 cGy
Gynaecology & Obstetrics
null
09961acd-c3fa-44e2-9e40-fa13b40dae37
single
A 40-year old alcoholic develops cough and fever. Chest X-ray show an air-fluid level in the superior segment of the right lower lobe. The most likely etiologic agent is:
Ans. D. AnaerobesOf the organisms listed, only anaerobic infection is likely to cause a necrotizing process Type III pneumococci have been reported to cause cavitary disease, but this is unusual. The location of the infiltrate suggests aspiration, also making anaerobic infection most likely. The superior segment of the...
4
Strept. pneumoniae
H influenzae
Legionella
Anaerobes
Medicine
Respiratory
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Myoclonus in children is best treated by :
null
2
Clonazepam
Sodium Valproate
Phenobarbitone
Ethosuximide
Pharmacology
null
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single
The antidote of poisoning due to Arninanita muscaria is
D i.e. Atropine Amanita muscaria & Amanita phalloides are poisonous mushrooms with parasympathetic (Cholinergic) symptoms. So AtropineQ is used as antidote in severe cases; but avoided in mild case as it excerhates delirium.
4
Physostigmine
Amyl nitrate
Methylene blue
Atropine
Forensic Medicine
null
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single
Baonella quintana causes:
Ans. is. 'a' i. e., Trench fever
1
Trench fever
Scrub typhus
Endemic typhus
Epidemic typhus
Microbiology
null
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single
The main poion of the ovarian aery, vein, and nerves are carried to and from the ovary by way of the:
The suspensory ligament attaches the ovary to the pelvic wall and carries within its folds the main poion of the ovarian vessels and nerves. The ovarian ligament attaches the inferior pole of the ovary to the uterus. The broad ligament is a double-fold of parietal peritoneum, which hangs over the uterus (mesentery of t...
1
Suspensory ligament
Ovarian ligament
Broad ligament
Mesovarium
Gynaecology & Obstetrics
null
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single
Barr body is absent in -
Ans. is 'b' i. e., Turner Barr body (Sex- chromatin)o It is a densely staining inactivated condensed 'X' chromosome that is present in each somatic cells of female,o It is found in the nucleus.o It is used as a test of genetic femaleness - it is possible to determine the genetic sex of an individual according as to whe...
2
Kleinfelter
Turner
Super female
None of the above
Pathology
Mendelian Disorders: Single-Gene Defects
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multi
Which of the following is most likely to produce a junctional scotoma
Junctional scotoma is due to lesion at junction of Optic nerve and chiasma. Which is m/c due to meningioma.
1
Meningioma
Craniopharyngioma
Pituitary gland enlargement
All the above
Ophthalmology
null
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multi
Perversion with pain to self: TN 09; Maharashtra 11
Ans. Masochism
4
Transvestism
Fetishism
Sadism
Masochism
Forensic Medicine
null
b0e0db62-2e78-4597-8d7b-66b7fcc63104
single
Which of the following H1 blocker has high anticholinergic activity :
null
2
Cetirizine
Chlorpheniramine
Fexofenadine
Astemizole
Pharmacology
null
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single
In acute inflammation endothelial retraction leads to
ref Robbins 8/e p45,9/ep74 Several mechanisms may contribute to increased vascu- lar permeability in acute inflammatory reactions: * Endothelial cell contraction leading to intercellular gaps in postcapillary venules is the most common cause of increased vascular permeability. Endothelial cell con- traction occurs rapi...
3
Delayed transient increase in permeability
Immediate transient increase in permeability
Delayed prolonged increase in permeability
Immediate transient decrease in permeability
Anatomy
General anatomy
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single
Aery of anatomical snuffbox?
Ans. is 'a' i.e., RadialAnatomical Snuffbox Triangular depression on the dorsal and radial aspect of the hand become visible when thumb is fully extended. BoundariesMedial/Posterior--Tendon of the extensor pollicis longus.Lateral/Anterior--Tendon of the extensor pollicis brevis and abductor pollicis longus.Roof--Skin a...
1
Radial
Ulnar
Brachial
null
Anatomy
null
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multi
Cysticercosis cellulosae causes infection with
null
3
Taenia saginata
Echinococcus granulosus
Taenia solium
Diphyllobothrium latum
Social & Preventive Medicine
null
5b0287fc-7e96-444f-9686-c9ea4407b98a
multi
Which of the following can be given orally?
MESNA ,is a drug used to reduce the undesired side effects of ceain chemotherapy drugs. It is referred to as a "chemoprotectant." and prophylactic agent used to reduce the incidence of ifosfamide-induced hemorrhagic cystitis. How this drug is given: As an injection or infusion through the vein (intravenous, IV). This i...
4
Cytosine arabinoside
Cisplatin
Doxorubicin
Mesna
Pharmacology
Chemotherapy
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multi
This cream is appropriate for all of the following procedures Except
EMLA (eutectic mixture of local anesthetics) is a eutectic mixture of 5 percent lidocaine and prilocaine that is used to produce anesthesia over intact skin. Its primary use is to produce anesthesia before venipuncture and lumbar puncture. In other settings, this cream has been used for anesthesia of split-thickness gr...
2
Venipuncture
Laceration repair
Lumbar puncture
Myringotomy
Anaesthesia
Anaesthesia of special situations
b246096e-4220-4df4-a8e3-2104b1f05017
multi
Not a fungal infection is:
Ans: A (Mycoses fungoides) Ref: Rook's Dermatology, 8th ed.Explanation:Mycosis Fungoides/Sezary SyndromeMycosis fungoides and Sezary syndrome are different manifestations of a tumor of CD4+ helper T cellsClinically, the cutaneous lesions of mycosis fungoides typically progress through three somewhat distinct stages, an...
1
Mycoses fungoides
Tinea nigra Palmaris
White Piedra
Black Piedra
Skin
Cutaneous Manifestations of Microvascular Occlusion Syndromes
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single
Antisocial personality is seen with :
A i.e. Drug abuse
1
Drug abuse
Paranoid schizophrenia
OCN
null
Psychiatry
null
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multi
All are viral causes of PUO except:
Ans: d (Leptospirosis) Ref: Harrison, 16 ed, p. 116, 17th ed, p. 132A quite straight forward question. The answer is leptospirosis because it is not a viral cause of PUOPUO: (Pyrexia of unknown origin)Definition:Temperature >38.3(IC on several occasionsOrA duration of fever of >3 weeksOrFailure to reach a diagnosis des...
4
EBV
CMV
HIV
Leptospirosis
Medicine
Infection
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multi
In disaster management following are practiced except
Disaster Management includes three aspects: 1. Disaster impact and response: Search, rescue, and first-aid * Field care * Triage * Tagging * Identification of the dead 2. Rehabilitation or recovery: * Water supply * Basic sanitation and personal hygiene * Food safety * Vector control 3. Mitigation: Measures designed ei...
3
Triage
Rehabilitation
Mass vaccination
Disaster response
Social & Preventive Medicine
All India exam
0059bce5-2cb2-4b4e-9c08-ab9e4063db97
multi
A patient having cystic medial necrosis with necrotising aeritis is suffering from?
Cystic medial degeneration . Smooth muscle loss . Fibrosis . Inadequate ECM synthesis . Accumulation of increasing amounts of amorphous proteoglycans Robbins 9 th edition page no. 345
4
Kawasaki disease
Temporal aeritis
Malignant hypeension
Aooaeritis
Pathology
Cardiovascular system
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single
A 27 year old female having a family history of autoimmune disease presents with the complaints of a skin rash and recurrent joint pains 3 months after delivering a baby. She is most likely to have which of the following disorders?
Acquired factor VIII deficiency Muscle and soft tissue bleeds are common. Bleeding into a joint results in severe pain and swelling, as well as loss of function, but is rarely associated with discoloration from bruising around the joint. Life-threatening sites of bleeding include bleeding into the oropharynx, where ble...
4
Megakaryocytic thrombocytopenia
Amegakaryocytic thrombocytopenia
Functional platelet defect
Acquired Factor VIII inhibitors
Pathology
Clotting factor
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single
Commonest cause of cataract
D i.e. Age related Radiation cataract is caused by exposure to almost all types of radiation energy such as infrared or heat (in glass-blowers or glass-workers, and iron-workers), irradiation caused by X-rays, gamma-rays or neutrons (in workers in atomic energy plant, survivors of atomic bomb and in patients inadequate...
4
Hereditary
DM
Trauma
Age related
Ophthalmology
null
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All are metabolic causes of liver disease except
Ans. is 'a' i.e., HistiocytosisMetabolic liver diseases can be classified into 3 categories:Manifestations due to hepatocellular necrosis: Galactosemia, hereditary fructose intolerance, tyrosinemia type I, Wilson disease, Hemochromatosis and al -antitrypsin deficiency.Cholestatic jaundice :Al -antitrypsin deficiency, B...
1
Histiocytosis
Hemochromatosis
Gaucher's disease
Wilson disease
Pediatrics
null
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multi
Not be cultured in Sabouraund's agar -
null
4
Blastomyces
Coccidiodes
Sporotrichum
Rhinosporidium seeberi
Microbiology
null
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single
The most common type of intussusception?
Ans. a (Ileocolic) (Ref. Bailey and Love 26th/pg. 114).ACUTE INTUSSUSCEPTION# Telescoping/invagination of one portion of the gut within an immediately adjacent segment; invariably it is the proximal into distal bowel. An intussusception is composed of three parts: the entering or inner tube; the returning or middle tub...
1
Ileocolic
Colocolic
Ileoileal
Retrograde
Surgery
Small & Large Intestine
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single
Holdswoh classification of thoracolumbar spine fracture is based on how many columns of spine?
Answer- A. TwoHoldswoh,s proposed two column concept of thoracolumbar spine fractureAntetior column : Consists veebral body, annulus fibrous, Anterior and posterior longitudinal ligamentsposterior column: Consists of veebral arch (pedicle, facets, laminae) and posterior ligaments (ligamentum flavum,interspinous and sup...
1
Two
Three
Five
Four
Surgery
null
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single
Chvostek’s sign is elicited by
The Clinical manifestations of hypocalcemia are mostly due to neuromuscular irritability.  The patients complains of paresthesias which are typically perioral or of the hands and feets  Tetany is the classic manifestation of hypocalcemia, the manifestations are :  Corpopedal Spasm o Laryngospasm o Seizures Latent tetan...
2
BP cuff in arm for 5 minutes
Facial nerve stimulation by tapping over the parotid
Tapping over extensor pollicis brevis
Tapping over flexor retinaculum
Medicine
null
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All of the following may be used to differentiate Central Retinal Venous Occlusion (CRVO) from ocular Ischemic syndrome due to carotid artery stenosis, Except –
Dilated retinal vein is seen both in CRVO and ocular ischemic syndrome; therefore, this feature cannot differentiate these two. However, in CRVO vein is tortuous while in ocular ischemic syndrome it is non-tortuous. Retinal artery perfusion pressure is decreased in ocular ischemic syndrome and is normal in CRVO. Ophtha...
1
Dilated retinal vein
Tortuous retinal vein
Retinal artery pressure
Opthalmodynamometry
Ophthalmology
null
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The commonest clinical pattern of basal cell carcinoma is -
• Locally invasive carcinoma, arises from the basal layer of the epidermis • MC type of skin cancer • 90% of BCC are seen in the face, above a line from the corner of mouth to lobule of ear. • MC site: Nose >Inner canthus of the eye, also known as Tear cancer. Types of BCC • Nodular: MC type of BCC, characterized by sm...
1
Nodular
Morpheaform
Superficial
Keratotic
Surgery
null
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single
The origin of ovaries from
null
1
Genital ridge
Genital tubercle
Wolffian duct
Miillerian duct
Anatomy
null
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single
Hyperprolactinemia is a side effect of
null
4
Bromocriptine
Levodopa
Amantadine
Metoclopramide
Pharmacology
null
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single
Rose-waaler test is
It is rapid slide haemagglutination test for detection of rheumatoid factor.
2
Precipitation test
Passive agglutination test
Neutralisation test
Complement fixation test
Microbiology
null
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single
Medical treatment of ectopic pregnancy is :
Methotrexate
1
Methotrexate
Progesterone
Oestrogen
Adriamycin
Gynaecology & Obstetrics
null
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single
A class C diabetic patient delivers at term, it is impoant to check her blood sugar levels immediately postpaum, since there may be a decrease in the insulin requirements of diabetic patients. This can be paly explained by :
Decrease in plasma chorionic somatomammotropin
3
Increased food intake
Decreased activity
Decrease in plasma chorionic somatomammotropin
All
Gynaecology & Obstetrics
null
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True about third hea sound is-
The third hea sound (S 3 ) occurs during the rapid filling phaseof ventricular diastole. It can be a normal finding in children,adolescents, and young adults; however, in older patients it signifieshea failure. A left-sided S 3 is a low-pitched sound best heard overthe left ventricular (LV) apex. A right-sided S 3 is u...
3
Present in constrictive pericariditis
Absent in aoic aneurysm
Absent in MS
Present in cardiac yamponade
Medicine
C.V.S
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Large way vegetation are characteristic of?
Ans. is 'b' i.e., SABE
2
SLE
SABE
Both
null
Pathology
null
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multi
Not a content of sphenopalatine fossa
null
3
Maxillary Artery
Maxillary nerve
Mandibular nerve
Pterygopalatina ganglion
ENT
null
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single
Anomalies of oral cavity most commonly found in which stage
null
1
Embryonic
Period Of Fertilization
Period Of Fetus
null
Anatomy
null
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Drug of choice for treatment of intermediate uveitis is
Treatment for Intermediate uveitis : Intravitreal or Posterior Subtenon's Steroid injections : Triamcinolone acetonide Steroids may also be given by subconjuntival route or by Subtenon's route
3
Cycloplegics
Analgesics
Steroids
Antibiotics
Ophthalmology
Uveitis
7567d44d-bd7e-41bb-9ca2-2b829a708499
single
Primary bile acid is?
Ans. is 'c' i.e., Chenodeoxycholic acid Primary bile acids are cholic acid and chenodeoxycholic acid, which are synthesized from cholesterol in liver. In the intestine some of the primary bile acids are conveed into secondary bile acids, i.e., deoxycholic acid (formed from cholic acid) and lithocholic acid (derived fro...
3
Deoxycholic acid
Lithocholic acid
Chenodeoxycholic acid
null
Biochemistry
null
fb4c385b-0147-48f5-ac78-0f26bd4b61f3
multi
Which β1 selective blocker is used in glaucoma:
null
3
Levobunolol
Timolol
Betaxolol
Carteolol
Pharmacology
null
b07345f2-9d5f-477b-a264-b7d7f7db91eb
single
What diagnosis is suggested by these spirography findings?
Answer A. Intrathoracic localized obstructionAn intrathoracic localized obstruction is demonstrated on spirography. The patient underwent flexible fiberoptic bronchoscopy, which revealed nearly complete (greater than 90%) occlusion of the distal trachea by a vascular mass. The patient recovered after endoscopic laser a...
1
Intrathoracic localized obstruction
Fixed inspiratory obstruction
Pneumothorax
Restrictive lung disease
Medicine
Respiratory
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single
Which is a yeast like fungi: September 2007
Ans. B: Candida Yeast like fungi grow paly as yeast and paly as elongated cells resembling hyphae.The latter form a pseudomycelium. Candida albicans is a pathogenic yeast-like fungus.
2
Cryptococcus
Candida
Blastomyces
Histoplasma
Microbiology
null
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single
Which one of the following variants of renal cell carcinoma has the worst prognosis -
null
4
Papillary
Tubuloalveolar
Chromophobe
Sarcomatoid
Pathology
null
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single
Observation of yeast cells with multiple budding in tissue in the form of a “the shape shown in below pictomyograph ” is highly suggestive of
Paracoccidioides brasiliensis causes paracoccidioido­mycosis. It is a dimorphic fungus that exists as a mold in soil and as a yeast in tissue. The yeast is thick­walled with multiple buds ("ship's wheel" appearance), in contrast to Blastomyces dermatitides, which has a yeast with a single bud that has a broad base. His...
3
Blastomycosis
Cccidiodomycosis
Paracoccidiodomycosis
Histoplasmosis
Unknown
null
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single
Which of the following is the most significant component of a behavioral program developed to help a mother deal with a child having oppositional defiant disorder?
Positive reinforcement of promoting desirable behaviours through rewards is the most significant component of the program used to deal with ODD.
1
Positive reinforcement
Punishment
School suspension
Strict parenting
Psychiatry
Miscellaneous
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single
Most common cause of leukocoria in newborn is
.
1
Congenital cataract
Toxocara infection
Retinoblastoma
CMV infection
Pathology
All India exam
c3486349-0243-4b8a-9e17-abb9922727a4
single
Which of the following is the site of bladder injury in abdominal hysterectomy is :
Posterior wall
2
Anterior wall
Posterior wall
Medial wall
Lateral wall
Gynaecology & Obstetrics
null
4a33573c-4661-4d05-a657-45aa6f9e51b5
multi
Paul -Bunnell test is positive in:
null
1
Infectious mononucleosis
Multiple myeloma
Malignant nerves
Rubella
Pathology
null
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A 10 year old child with aggressive, self mutilating behavior and poor concentration is brought with presenting complaints of joint pain and reduced urinary output. Child's presentation is most likely due to the deficiency of which enzyme?
The child in the question stem is showing features of Lesch nyhan syndrome caused by deficiency of HGPase. Hypoxanthine guanine phosphoribosyl transferase is an enzyme responsible for the formation of hypoxanthine to inosoic acid and guanine to guanylic acid. This enzyme deficiency can present in a complete form only i...
1
HGPase
Adenosine Deaminase
APase
Acid Maltase
Biochemistry
null
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A 56 year old man has been having bloody bowel movements on and off for the past several weeks. He repos that the blood is bright red, it coats the outside of the stools, and he can see it in the toilet bowl even before he wipes himself. When he does so, there is also blood on the toilet paper. After fuher questioning,...
The combination of red blood coating the stools and a change in bowel habit and stool caliber spells out cancer of the rectum in someone in this age group. Anal fissure is typically seen in young women who have very painful bowel movements with streaks of blood. Pain is the dominant symptom in this condition. Cancer of...
3
Anal fissure
Cancer of the cecum
Cancer of the rectum
External hemorrhoids
Surgery
null
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What is the best procedure to control external hemorrhage in an event of accidental injury?
Direct firm pressure applied over the bleeding area or the involved aery at a site that is proximal to the wound is the best way to control external hemorrhage. A firm pressure dressing is applied and the injured pa is elevated to stop venous and capillary bleeding if possible. If the injured area is an extremity it sh...
2
Elevation
Direct pressure
Proximal tourniquet
Aery forceps
Surgery
null
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5day baby full term breast fed with bilirubin 14mg Idl weight is 2700g what should be done next ?
Age Min TSB to sta phototherapy 24hrs > 10mg 1dL 48hrs >13mg 1dL 72hrs >15mg1dL 96hrs and beyond >18mg1dL Reference: GHAI Essential pediatrics, 8th edition
1
Normal newborn care
Phototherapy
Exchange transfusion
stop breastfeeding
Pediatrics
All India exam
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The paradoxical response of GH release to TRH is seen in -
TRH stimulates the secretion of prolactin as well as TSH, Normally it does not affect growth hormone secretion but in acromegaly TRH induced growth hormonal stimulation Occurs. Note: "In prolactinomas paradoxical response of TRH to prolactin occurs". In normal individuals, TRH stimulates prolactin release Where as in...
2
Prolactinoma
Acromegaly
Malnutrition
Pitutary adenoma
Medicine
null
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How many mm from the limbus is the safest site of intravitreal injection?
(Refer: AK Khurana Comprehensive Ophthalmology, 6th edition, pg no. 171)Intravitreal injection (distance from Limbus)For aphakics-3mmFor pseudophakes-3.5mmFor phakics-4mm
3
1-2 mm
2-3 mm
3-4 mm
4-5 mm
Ophthalmology
Vitreous and retina
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Which one of the following cofactors must be utilized during the conversion of acetyl-CoA to malonyel-CoA?
FAD The key enzymatic step of fatty acid syn thesis is the carboxylation of acetyl-CoA to form malonyl-CoA. The carboxyl of biotin is covalently attached to an E-amino acid group of a lysine residue of acetyl-CoA carboxylase. The reaction occurs in two stages. In the first step, a carboxybiotin is formed: HCO3- + bioti...
4
Thiamine pyrophosphate
Acyl carrier protein (ACP)
Biotin
FAD
Surgery
null
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Which of the following is not consider to be a slow viruse diseases -
kuru,scrapie,&CJD Are caused by slow virus REF:ANATHANARAYANAN MICROBIOLOGY NINTH EDITION PAGE.557
4
Kuru
Scrapie
Creutzfeldt Jakob disease
Sarcoidosis
Microbiology
Virology
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Sleepwalking occur in which stage of sleep -
Sleep walking (somnambulism) is seen in stage 3 & 4 of NREM sleep.
3
REM
NREM stage
NREM stage 3 or 4
Can occur in any stage of NREM sleep
Psychiatry
null
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Which one of the following device provides fixed performance oxygen therapy:
B i.e. Ventimask Ventimask or venturimasks are high flow or fixed performance (performance not affected by changes in patient's tidal volume and respiratory rate) oxygen delivery devicesQ delivering accurate oxygen concentration
2
Nasal Cannula
Venturi mask
O2 by T-piece
SO2
Anaesthesia
null
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House Brackmann scale is for which nerve?
null
1
Facial nerve
Trigeminal
Optic
Hypoglossal
Anatomy
null
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Nerve supply of tip of nose
Nerve supply General sensory nerves derived from the branches of trigeminal nerve are distributed to whole of the lateral wall: Anterosuperior quadrant is supplied by the anterior ethmoidal nerve branch of ophthalmic nerve. Anteroinferior quadrant is suplied by the anterior superior alveolar nerve branch of infraorbita...
1
Ext nasal branch of ophthalmic division of
Inferior orbital nerve
Buccal br of mandibular nerve
Orbital of maxillary n
Anatomy
Head and neck
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The scoring given in periodontal index for gingivitis is
null
2
1
2
4
6
Dental
null
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Features of carcinoma penis include all except: March 2007
Ans. C: Hypospadias is a premalignant lesion Following as risk factors for penile cancer: Human papillomavirus (HPV) infection, smoking, smegma, phimosis, treatment of psoriasis, age, and AIDS. The other etiologic factor most commonly associated with penile carcinoma is poor hygiene. Lichen sclerosus (also known as bal...
3
Metastasize to inguinal lymph nodes
Surgery is the treatment of choice
Hypospadias is a premalignant lesion
Circumcision provides protection
Surgery
null
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A 60-year-old male, chronic smoker, presented with fatigue and chest pain. On examination, there was inset left eyeball with drooping upper left eyelid and reduced left pupil size. Which of the following is the most likely diagnosis in this condition?
Most tumors of the apex of the lung are adenocarcinomas Pancoast tumors - apical lung tumors in the superior pulmonary sulcus tend to invade the neural structures around the trachea, including the cervical sympathetic plexus. Involvement of sympathetic fibers gives rise to severe pain in the distribution of the ulnar n...
1
Squamous cell carcinoma involving the apex of his left lung
Adenocarcinoma involving left mainstem bronchus
A small-cell carcinoma involving the hilum of his left lung
Bronchioloalveolar carcinoma involving the left lower lobe
Pathology
Lung Tumor
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A patient died during surgery. The relatives allege that death was due to negligence. According to a recent Supreme Cou judgment, doctor can be charged for Medical Negligence under section 304-A, only if:
Ans. c. There is gross negligence A physician can be charged with criminal negligence in Section 304 A, when a patient dies from the effects of anesthesia during, an operation or other kind of treatment, if it can be proved that the death was the result if malicious intention, or gross negligence. "Section 304-A deals ...
3
There is corporate negligence
Negligence is from inadveent error
There is gross negligence
It falls under the doctrine of Res Ipsa Loquitor
Forensic Medicine
null
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Localization in insulinoma is best with -
The insulinoma might be localized by noninvasive means, using ultrasound, CT scan, or MRI techniques. An indium-111 pentetreotide scan is more sensitive than ultrasound, CT, or MRI for detection of somatostatin receptor positive tumors, but not a good diagnostic tool for insulinomas. An endoscopic ultrasound has a sens...
4
Contrast computerized tomography
Margnetic resonance imaging
Somatostatin receptor scintigraphy
Selective angiography
Medicine
G.I.T
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The nerve mediating pain of External hemorrhoids is:
-External hemorrhoids --> present below pectinate line , painful bleeding is present --> pain carried by Inferior Rectal Nerve (branch of pudendal nerve). -Internal haemorrhoids --> present above pectinate line --> painless bleeding is its feature.
2
Hypogastric nerve
Inferior rectal nerve
Pelvic splanchnic nerve
Sympathetic plexus
Anatomy
Development of GU system and Neuro-vascular supply of pelvis & perineum
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Myelin sheath in the central nervous system is formed by
Oligodendrocytes are responsible for myelination in the CNS. In the PNS, Schwann cells form the myelin sheath. The process of myelination begins before bih and is not complete until a year or more after bih. (Ref: Vishram Singh textbook of neuroanatomy, second edition, pg- 19)
3
Schwann cell
Microglia
Oligodendrocytes
Protoplasmic astrocytes
Anatomy
Brain
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Female presents with history of color change from pallor to cyanosis on exposure to cold in fingers. This condition is mostly associated with?
A. i.e. Scleroderma Raynaud's phenomenon (i.e. cold/vibration/emotional stress-exposure Vt pallor --> cynosis & finally erythemaQ of digits, ear & tip of nose) is almost always present (along with skin sclerosis) and is often earliest featureQ of Systemic sclerosis (Scleroderm). It may precede extensive skin & internal...
1
Scleroderma
Leukemia
Lung infections
Hepatosplenomegaly
Skin
null
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ESR is raised in -a) Sickle cell anaemiab) Multiple myelomac) Acute myocardial Infarctiond) Angina pectoris
null
1
bc
c
ac
ad
Pathology
null
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True statements are all except:
1.) The gene encoding for MHC molecules are clustered on small segment of chromosome 6. 2.) MHC II molecules are present on all the APC's (Antigen Presenting Cells), and Monocyte are type of Antigen Presenting cell. 3.) Class III is present adjacent to Class I and Class II. 4.) Class III encodes for complement protein.
4
Chromosome six has the genes for MHC
Genes encoding complement proteins are located adjacent to class I
Monocytes have MHC II antigens on their surface
Class III does not encode complement
Pathology
Basic Concepts
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Hypothyroidism is caused by which of the following anti-tubercular drug -
Ans. is 'a' i.e., PAS Adverse effects of para-amino salicylic acid (PAS) --> Anorexia, nausea, epigastric pain, rashes, goiter (hypothyroidism), fever, malaise, liver dysfunction, and blood dyscrasias. Adverse effects of ethionamide :Anorexia, nausea, vomiting, abdominal pain, hepatitis, optic or peripheral neuritis, m...
1
PAS
Ethionamide
Cycloserine
Pyrazinamide
Pharmacology
null
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single
During growth cycle of a child, usually at what age childhood ends and adolescence stas?
WHO/UN definitions: Adolescent - 10-19 years Youth - 15-24 years Young people - 10-24 years Ref: Ghai essential pediatrics, 6th edition, Page 66.
2
8 years
10 years
12 years
16 years
Pediatrics
null
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multi
Which of the following can lead to infiltration of ear lobules, loss of nails and resorption of distal phalanges?
Ans. B. Lepromatous leprosy. (Ref. Harrison's 18th/pg. 1362)LEPROSYSpecific symptoms vary depending on the type of leprosy.# Tuberculoid leprosy: A rash appears, consisting of one or a few flat, whitish areas. Areas affected by this rash are numb because the bacteria damage the underlying nerves.# Lepromatous leprosy: ...
2
Tuberculoid leprosy
Lepromatous leprosy
Indeterminate leprosy
Any of the above
Skin
Bacterial Infection of Skin
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One of the following molecules acts as a mobile electron carrier in the respiratory chain
Ref: Harper&;s Biochemistry; 30th edition; Chapter 13; The Respiratory Chain & Oxidative Phosphorylation
4
Ubiquinone
FADH2
FeS
Cytochrome b
Biochemistry
Metabolism of carbohydrate
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multi
Symptom of hypoglyemia is -
Ref - Davidsons 23e p739
1
Sweating
Bradycardia
Chest pain
Breathlessness
Medicine
Miscellaneous
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single
True about DNA structure
Deoxyribonucleic acid (DNA) stores information for the synthesis of specific proteins. DNA has deoxyribose as its sugar. DNA consists of a phosphate group, a sugar, and a nitrogenous base. The structure of DNA is a helical, double-stranded macromolecule with bases projecting into the interior of the molecule. These two...
3
Purines are adenine and guanine & pyrimidines are uracil and cytosine
Waston and Crick discovered structure in 1973
Deoxyribose - phosphate backbone with bases stacked inside
Mainly consists of left handed helix
Biochemistry
Metabolism of nucleic acids
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multi
A 36-year-old female presents with heavy menstrual bleeding. She has one child of 7 years. USG shows a single 3x3 cm submucosal fibroid. Hemoglobin is 10.5 gm/dl. What is the best treatment option for her?
Ans. is c, i.e. Hysteroscopic myomectomyThis patient is having heavy menstrual bleeding due to fibroid, i.e. she is symptomatic and hence management has to be done. Best management in fibroid is surgery. Since she is only 36 years and has one child We will go for myomectomy.Submucous fibroid <5cm, should be removed hys...
3
GnRH injection
UAE
Hysteroscopic myomectomy
Laparoscopic myomectomy
Gynaecology & Obstetrics
Miscellaneous (Gynae)
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multi
All of the following are true about dermatitis herpetiformis except:
IgA antibodies are seen against TTG.
3
Severe itchy skin lesions over extensor surfaces
Most of the patients have underlying coeliac disease
It is characterized by IgE anitbodies against TTG : Tissue transglutaminase
Dapsone is the drug of choice
Dental
null
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multi
Delta bilirubin is ______ bilirubin _____ bound to albumin.
Delta bilirubin or biliprotein is the fraction of conjugated bilirubin that is covalently bound to albumin. This is responsible for the lab finding of persistent hyperbilirubinemia even after the disappearance of jaundice in cases of obstructive jaundice. -Chromatographic fractionation of serum bilirubin: a bilirubin u...
1
Conjugated, covalently
Unconjugated, non-covalently
Conjugated, noncovalently
Unconjugated, covalently
Biochemistry
HAEM synth and porphyrias
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Cushing syndrome as paraneoplastic syndrome is seen with all malignancies, EXCEPT:
Paraneoplastic Syndrome Ectopic Hormone Typical Tumor Hypercalcemia of malignancy Parathyroid hormone-related protein Squamous cell (head and neck, lung, skin), breast, genitourinary, gastrointestinal 1,25 dihydroxyvitamin D Lymphomas Parathyroid hormone Lung, ovary Prostaglandin E2 (PGE2) Renal, lung Syndrome of inapp...
4
Bronchial carcinoid
Thymus
Medullary carcinoma thyroid
Papillary carcinoma thyroid
Medicine
null
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multi
Prevention of emergence of risk factor is -
It is the prevention of the emergence or development of risk factors in countries or population groups in which they have not yet appeared.
1
Primordial prevention
Primary prevention
Secondary prevention
Tertiary prevention
Social & Preventive Medicine
null
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single
Blalock and Taussig shunt is done between -
Ans. is 'a' i.e., Aoa to Pulmonary Aery Blalock Taussig shunt consists of subclan aery (br. of aoa) and pulmonary aery anastamosis. This inturn actually establishes a shunt between the aoa (Via the subclan aery) and the pulmonary aery. Management of T.O.F. Medical Management Limited to management of complications and c...
1
Aoa to pulmonary aery
Aoa to pulmonary vein
Subclan aery to pulmonary vein
Subclan vein to aery
Pediatrics
null
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single
Accessory meningeal artery enters cranial cavity through:
Accessory meningeal artery is a branch of 1st part of Maxillary artery.  It enters the cranium by passing through foramen ovale. It supplies meninges and infratemporal fossa.
4
Foramen lacerum
Foramen rotundum
Foramen spinosum
Foramen ovale
Anatomy
null
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single
The following statements about thyroglossal cyst are true, except
Thyroglossal cysts are the most common cause of midline neck masses. Can occur anywhere along the path of the thyroglossal duct, from the base of the tongue to the suprasternal notch (in the midline) Treatment must include excision of the whole thyroglossal tract, which involves removal of the body of the hyoid bone an...
3
Frequent cause of anterior midline neck masses in the first decade of life
The cyst is located within 2 cm of the midline
Incision and drainage is the treatment of choice
The swelling moves upwards on protrusion of tongue
Surgery
Endocrinology and breast
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A 10 year old child develops hematuria after 2 days of diarhoea. Blood film shows fragmented RBCs. Which of the following is likely diagnosis-
null
3
Acute pyelonephritis
Disseminated intravascular coagulopathy
Haemolytic uremic syndrome
Haemolytic crises
Medicine
null
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