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Treatment of severe intraoral infections in children differs from that in adult because:
Treatment of severe intraoral infections in children differs from that in adult because dehydration occurs more rapidly and severely in children.
2
More children are allergic to penicillin
Dehydration occurs more rapidly and severely in children
Leucocytopenia develops more frequently in children
Incidence of bleeding disorders is greater in children
Dental
null
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multi
An 80-year-old patient presents with a midline tumor of the lower jaw, involving the alveolar margin. He is edentulous. Treatment of choice is:
Mandibulectomy Marginal mandibulectomy Segmental mandibulectomy - Conservative mandibulectomy - Refers to paial excision of the superior poion of mandible in veical phase - Inner coical surface and a poion of underlying medullary cavity is excised - Preserve mandibular continuity - Indicated when tumor lies within I cm of the mandible or abuts the periosteum without evidence of direct bony invasion - Entire through and through segment of mandible is resected - Results in mandibular discontinuity - Require major reconstructive procedure for cosmetic and functional purposes - Indications: 1. Invasion of medullary space of mandible 2. Tumor fixation to occlusal surface of mandible in edentulous patients 3. Invasion of tumor into the mandible mandibular or mental foramen 4. Tumor fixed to the mandible.
3
Hemimandibulectomy
Commando operation
Segmental mandibulectomy
Marginal mandibulectomy
Surgery
Oral cavity
db203ade-91f3-4351-9735-6fe9ffe3e0d5
single
Which of the following is not sexually transmitted-
Bacterial Diseases transmitted with sexual intercourse Neisseria gonorrhoeae Chlamydia trachomatis Treponema pallidum Haemophilus ducreyi Note the list does not include Haemophilus Vaginalis, the cause of bacterial vaginosis Viruses transmitted by sexual intercourse HIV (types 1 and 2) Human T-cell lymphotropic virus type I(HTLV) HSV type 2 HPV (multiple genotypes) Other infections like Trichomoniasis( Protozoal) , Candida and Phthirus pubis
1
Echinococcus
Chlamydia
Treponema pallidum
Nesseria gonorrhae
Gynaecology & Obstetrics
Genital Tract Infections (Too hot to handle!)
49dfd7db-1151-411d-be71-3c78832f0e21
multi
Which one of the following congenital heart diseases has cyanosis without cardiomegaly and/or congestive heart failure –
Cardiomegaly and CHF do not occur in Fallot's tetrology. No Cardiomegaly First you should know the following facts : - Pressure overload to ventricles causes concentric hypertrophy without dilatation. Volume overload to ventricles causes hypertrophy with dilatation → Eccentric hypertrophy. Due to pulmonary stenosis, there is pressure overload to right ventricle → Concentric hypertrophy of right ventricle without dilatation → No Cardiomegaly. No CHF The VSD of TOF is always large enough to allow free exit to the right to left shunt. Since the right ventricle is effectively decompressed by the VSD, CHF never occurs in TOF.
2
Transposition of great arteries
Fallot's tetralogy
Congenital mitral regurgitaion
Congenital pulmonary stenosis
Pediatrics
null
ae889a29-4c15-4fff-8b11-8d2de8cf9579
multi
Which drug can be given in G6PD deficiency?
Chloroquine rarely cause hemolysis in patients with G6PD deficiency. Drugs initiate hemolysis and should be avoided: Dapsone Methylthioninium chloride (methylene blue) Phenazopyridine Primaquine Rasburicase Tolonium chloride (toluidine blue) Nitrofurantoin, sulfonamides Aspirin, nonsteroidal anti-inflammatory drugs Quinidine Naphthalene Attacks can also be associated with infections (such as pneumonia, viral hepatitis, and Salmonella) and diabetic ketoacidosis. Finally, foods such as a beans have been implicated. Ref: Linker C.A., Damon L.E., Damon L.E., Andreadis C. (2013). Chapter 13. Blood Disorders. In M.A. Papadakis, S.J. McPhee, M.W. Rabow, T.G. Berger (Eds), CURRENT Medical Diagnosis & Treatment 2014.
1
Chloroquine
Probenecid
Aminopyrine
Primaquine
Pharmacology
null
b3a1acc9-9a3e-4dae-b4fc-20f9d9886918
single
Which is true of closed dental camp?
null
1
Preselected area like school for camp
Serving large number of people in community
Resent close dental camp
No such term
Dental
null
ca12b28b-c9e5-475c-97f8-38e41b12cba3
multi
Which of the following is responsible for protection from ultraviolet rays: September 2011
Ans. D: Melanocyte Structure involved in protection against ultraviolet radiation is melanin produced by melanocytes and transferred to keratinocytes
4
Stratum corneum
Langerhans cells
Apocrine sweat glands
Melanocyte
Skin
null
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single
In case of uncontrolled epistaxis, ligation of internal maxillary artery is to be done in the -
null
2
Maxillary antrum
Pterygopalatine fossa
At the neck
Medial wall of orbit
ENT
null
be401f85-ac94-49e3-a9a7-4852fbfe4b6e
multi
All are useful in acute appendicitis except:
Ans: d (Purgation)Ref: Bailey & Love, 24,hed, p. 1211 &23rded, p. 1085
4
Antibiotics
Analgesics
IV fluids
Purgation
Surgery
Vermiform Appendix
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multi
Prussak's space is seen in ?
Ans. is 'a' i.e., EpitympanumPrussak's space is a small space between the shrapnel's membrane/pars flaccida laterally. neck of malleus medially, sho process of malleus below and lateral process of malleus above.Prussak's space communicates with epitympanum through a posterior gap.Prussak's space is impoant because it is a site for pars flaccida acquired cholesteatoma formation.
1
Epitympanum
Hypotympanum
Mesotympanum
Ear Canal
Pathology
null
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single
Protein A of staphylococcus binds to -
Ans. is 'b' i.e., IgG Virulence factors of staphylococcus aureuso Protein 'A' binds to Fc terminal of IgG (IgG 1,2 & 4 but not IgG3) and prevents opsonophagocytosis by PMNs . It is a B-cell mitogen. It is chemotactic, anti-complementory and antiphagocytico Heat stable nuclease (DNAase) is a characteristic feature of staph aureus.o Staphylococcus produces five cytolytic toxins, consisting of four hemolysins (alpha, beta, gamma and delta) and a leucocidin.o a - hemolysin is the most important hemolysin.o Beta - hemolysin is a sphingomyelinase. It exhibits a hot-cold phenomenon, the hemolysis being initiated at 37degC, but becoming evident only after chillingo Leucocidin is also called the Panton-valentine toxin.o Staphylococcal leucocidin and gamma lysin have been grouped as synergohymenotropic toxins.o Toxic shock syndrome toxin (TSST), exfoliative toxin and enterotoxins are superantigens which are potent activators of T lymphocytes and lead to an excessive and dysregulated immune response with release of cytokines IL-1, IL-2, TNF-a and IFN-g.o Enterotoxin is responsible for food poisoning, o Exfoliative (epidermolytic) toxin# Responsible for staphylococcal scalded skin syndrome (S.S.S.S.).# Severe form of SSSS is known as Ritter's disease in newborn and toxic epidermal necrolysis in older patients. Milder forms are pemphigus neonatorum and bullous impetigo.o Hyaluronidase is helpful in persistent skin infection.
2
IgA
IgG
IgD
IgE
Microbiology
Bacteria
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single
A farmer who is working in poultry developed acute onset of fever with chills. On physical examination, there is hepatosplenomegaly and lymphadenopathy. Blood culture shows Brucella abous. He must have got the infection through all the following ways, EXCEPT:
The infection is transmitted from animals to humans. Brucella abous (cattle), B suis(hogs), and B melitensis (goats) are the main agents. Transmission to humans occurs by contact with infected meat (slaughterhouse workers), placentae of infected animals (farmers, veterinarians), or ingestion of infected unpasteurized milk or cheese. Ref: Schwaz B.S. (2014). Chapter 33. Bacterial & Chlamydial Infections. InPapadakis M.A., McPhee S.J., Rabow M.W. (Eds), CURRENT Medical Diagnosis & Treatment 2014.
3
Infected meat
Ingestion of raw milk
Man to man
Contact with aboed fetuses
Social & Preventive Medicine
null
fa668a5e-12af-4ac5-810a-caeba02dcb30
multi
Malaria protection comes from all except ?
Ans. is 'd' i.e., Acanthocytosis Types of anemia that have protective effect against P. falciparum malaria : ? G6PD deficiency, Sickle cell anemia, Thalassemia, HbC, Pyruvate kinase deficiency
4
G6PD deficiency
Thalassemia
Sickle cell anemia
Acanthocytosis
Pathology
null
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multi
A 22-year old software engineer was brought in an unconscious state to the casualty. Clinical examination revealed features suggestive of shock, DIC and multisystem failure. CSF and petechial rashes yielded gram-negative diplococcic, which subsequently grew on modiefied Thayer-Martin medium. This isolation is known to be associated with-
Ans- A Waterhouse-Friderichsen Syndrome This uncommon but catastrophic syndrome is characterized by the following:An overwhelming bacterial infection, which is classically associated with Neisseria meningitidis septicemia but occasionally is caused by other highly virulent organisms, such as Pseudomonas species, pneumococci, Haemophilus influenzae, or staphylococciRapidly progressive hypotension leading to shockDisseminated intravascular coagulation with widespread purpura, particularly of the skinRapidly developing adrenocortical insufficiency associated with massive bilateral adrenal hemorrhage Whatever the basis, the adrenals are converted to sacs of clotted blood virtually obscuring all underlying detail.
1
Waterhouse-Fridericheen syndrome
Fitz-Hugh-Curtis syndrome
Job's syndrome
Toxic shock syndrome
Unknown
null
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MEN-1 include all except
MEN 1 is characterised by the triad of tumours in the anterior pituitary gland, mostly presenting as prolactinomas or non-functioning tumours, hyperplasia of the parathyroids causing primary hyperparathyroidism (pHPT) and Pancreaticoduodenal endocrine tumours (PETs). also called Wermer's syndrome. It is caused by germline mutations in the menin gene, located on chromosome 11.MEN 2A is characterised by the combination of MTC, pHPT and mostly bilateral phaeochromocytomas. MTC combined with phaeochromocytoma alone is called Sipple's syndromeMEN 2B comprises MTC, phaeochromocytoma and characteristic facial and oral mucosal neurinomas and intestinal ganglioneuromatosis, accompanied by a Marfanoid habitus.Ref: Bailey and Love 27e pg: 856
4
Prolactiomas
Parathyroid hyperplasia
Pancreatic endocrine tumours
Medullary carcinoma thyroid
Surgery
Endocrinology and breast
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In which of the following conditions, MTP can be indicated -a) Pregnancy caused by rapeb) Husband is willing but mother is not agreeingc) If maternal health is in dangerd) Pregnancy after contraceptive failuree) Pregnant women have received cytotoxic drugs
Pregnancy due to rape, danger to maternal health, receiving cytotoxic drugs (can cause fetal damage and risks of a born child with physical/mental abnormalities) and pregnancy due to contraceptive failure are indications for abortion under MTP act.
3
bce
bde
acde
abde
Forensic Medicine
null
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single
Host related biological propeies of a disease agent are the following except
Host related biological propeies of disease agent are Infectivity Pathogenicity Virulence Ref : parks textbook of PSM 24th edition page no : 41
4
Virulence
Infectivity
Pathogenicity
Communicablity
Social & Preventive Medicine
Concept of health and disease
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multi
Huxley- Henley layers is a pa of
Hair * Hair is derived from ectoderm, but dermal papilla is of mesoderm-derivation * Hair follicle is positioned at an angle; base of follicle typically within the subcutaneous fat Longitudinal anatomy * Infundibulum: upper poion of follicle extending from surface of epidermis to opening of sebaceous gland * Isthmus: middle poion extending from opening of sebaceous gland duct to inseion of arrector pili muscle (bulge), lined by outer root sheath (ORS), no inner root sheath (IRS) * Inferior segment or lower hair follicle: extending from base of isthmus to hair bulb; consists of matrix cells and envelops dermal papilla; lined by IRS; ORS present but not keratinized; widest diameter termed critical line of Auber (below this is where bulk of mitotic activity occurs); melanocytes in bulb provide melanosomes for hair color * Cross-sectional anatomy:- from outer to inner layer: * Glassy membrane - ORS - Henle's layer (IRS) - Huxley's layer (IRS) - cuticle (IRS) - hair shaft cuticle - coex --> Medulla. Ref:- Sima Jain; pg num:- 13,14
3
Nail
Skin
Hair
Sweat glands
Dental
miscellaneous
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single
A 37-year-old female presents to the emergency room with a fever. Chest x-ray shows multiple patchy infiltrates in both lungs. Echocardiography and blood cultures suggest a diagnosis of acute bacterial endocarditis limited to the tricuspid valve. Which of the following is the most probable etiology?
The most probable etiology of bacterial endocarditis involving the tricuspid valve is illicit intravenous drug use, which can introduce skin organisms into the venous system that then attack the tricuspid valve. Staphylococcus aureus accounts for between 60% and 90% of cases of endocarditis in intravenous drug users. The endocarditis associated with congenital hea disease typically involves either damaged valves or atrial or ventricular septal defects. The tricuspid valve is not paicularly vulnerable. Rheumatic fever most commonly damages the mitral and aoic valves, and tricuspid damage is usually less severe and seen only when the mitral and aoic valves are heavily involved. Consequently, secondary bacterial endocarditis involving only the tricuspid valve in a patient with a history of rheumatic fever would be unusual. Rheumatoid ahritis is not associated with bacterial endocarditis. Ref: Brooks G.F. (2013). Chapter 14. The Streptococci, Enterococci, and Related Genera. In G.F. Brooks (Ed), Jawetz, Melnick, & Adelberg's Medical Microbiology, 26e.
2
Congenital hea disease
Illicit drug use
Rheumatic fever
Rheumatoid ahritis
Microbiology
null
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multi
Karyotype of Complete mole is?
ANSWER: (B) 46XXREF: Dutta 6th ed p. 201Repeat in December 2011See APPENDIX-63 for "COMPLETE AND PARTIAL HYDATIDIFORM MOLES" APPENDIX - 63Complete and Partial Hydatidiform Moles:FeaturePartial Hydatidiform MoleComplete Hydatidiform MoleKaryotype69XXY, Triploid, paternal and maternal origin46XX, Diploid, mostly paternal originImmunohistochemistryhCGWeakStrongPlacental alkaline phosphataseStrongWeakhPLvariableWeakPathology Fetus or amnion, fetal vessels Hydropic villiTrophoblastic proliferationPresentVariable, often focal FocalAbsentPronounced, generalizedVariable, often markedClinical Mole clinical diagnosisUterus large for datesMalignant sequelaeRareRare<5%Common30%-50%6%-36%
2
46 XY
46 XX
69 XXX
69 XXX
Gynaecology & Obstetrics
Choriocarcinoma
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single
Which of the following is an epiphyseal lesion?
Ans. is 'a' i.e., Chondroblastoma
1
Chondroblastoma
Chondrosarcoma
Fibrosarcoma
Non ossifying fibroma
Surgery
null
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single
Histologic examination of lung tissue reveals multiple suppurative, neutrophil-rich exudates that fill the bronchi and bronchioles and spill over into the adjacent alveolar spaces only. The majority of lung tissue is not involved in this inflammatory process. Hyaline membranes are not found. This histologic appearance best describes
Pulmonary infections may be caused by bacteria, fungi, viruses, or mycoplasma. Bacterial infections generally result in a polymorphonuclear (neutrophil) response. Bacterial infection of the lung (pneumonia) results in consolidation of the lung, which may be patchy or diffuse. Patchy consolidation of the lung is seen in bronchopneumonia (lobular pneumonia), while diffuse involvement of an entire lobe is seen in lobar pneumonia. Histologically, bronchopneumonia is characterized by multiple, suppurative neutrophil-rich exudates that fill the bronchi and bronchioles and spill over into the adjacent alveolar spaces. In contrast, lobar pneumonia is characterized by four distinct stages: congestion, red hepatization, gray hepatization, and resolution Reference: Robbins & Cotran Pathologic Basis of Disease, 9edition.
2
Bronchiectasis
Bronchopneumonia
Lobar pneumonia
Interstitial pneumonitis
Pathology
miscellaneous
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single
Tissue suturing glue contains:
Most tissue adhesives or glue are cyanoacrylate polymers, such as n-butyl-2-cyanoacrylate (eg, Histoacryl®, PeriAcryl®) or 2-octyl cyanoacrylate (eg, Dermabond®, Surgiseal). Cyanoacrylate tissue adhesives are liquid monomers that undergo an exothermic reaction on exposure to moisture (eg, on the skin surface), changing to polymers that form a strong tissue bond. When applied to a laceration, the polymer binds the wound edges together to allow normal healing of the underlying tissue. Compared with wounds closed with sutures, the tensile strength of wounds closed by tissue adhesives is less at the time of initial application, but equalizes by one week post-repair. Advantages: Less painful application, and sometimes no need for local anesthetic injection More rapid application and repair time Cosmetically similar results at 12 months post-repair Waterproof barrier Antimicrobial properties Better acceptance by patients No need for suture removal or follow-up Indications and contraindications: For use of tissue adhesives the wound needs to be clean, dry with near perfect hemostasis and under no tension. Complex stellate lesions or crush injuries should not be closed with tissue adhesives since good wound approximation is difficult to achieve. Tissue adhesives are not recommended for lacerations of the hands, feet, or joints, since repetitive movements could cause the adhesive bond to break before sufficient tensile strength is achieved. Tissue adhesives are not recommended for the oral mucosa or other mucosal surfaces or areas of high moisture such as the axillae and perineum. Lacerations involving the hairline or vermilion border require more precision, and should be repaired with traditional sutures.
1
Cyanoacrylate
Ethanolamine oleate
Methacrylate
Polychloroprene
Surgery
null
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single
Pain in early labor is transmitted through
.
1
T11 - T12
L2 - L3
L4 - L5
S2 - S3
Pharmacology
All India exam
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single
Snake that causes paralysis with convulsions: NEET 14
Ans. Cobra
3
Vipers
Sea snakes
Cobra
Krait
Forensic Medicine
null
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single
A female patient has adenocarcinoma uterus along with sarcoma of uterus. It is known as -
Of the Uterine Sarcomas Almost 50% of are Mixed and are called the Mixed Mesodermal tumors (Synonymously called Mixed mullerian tumors). These mixed tumors can be Homologous 25% Heterologous 20% Adencarcinomas in 5% cases. The other Uterine sarcomas are Leiomyosarcoma in 33% cases and Stromal sarcoma in 16% cases
3
Homologous sarcoma
Sarcoma uterus
Mixed mullerian carcinogenesis
Heterologous sarcoma
Gynaecology & Obstetrics
Endometrial Carcinoma
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single
A patient presented to you after an assault and penetrating knife injury to the abdomen. X-Ray shows gas under the diaphragm. Most common organ damaged in this case:
Ans.B intestine X-Ray shows gas under the diaphragm suggests perforating injury . Most common organ damaged in Penetrating or stab injury : Liver Most common organ damaged in Perforating injury : Small Intestine Most common organ damaged in Blunt abdominal injury : Spleen Most common organ damaged in Seat belt injury : Mesentry Most common organ damaged in Blast injury : Head above water : TM Below water : GIT Most common organ damaged in Deceleration injury- Dudodenojejunal flexure
2
Spleen
Intestine
Liver
Lung
Unknown
null
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single
Which of the following is not a feature of juvenile CML?
Philedelphia chromosome positivity is a feature of adult CML. Juvenile CML is commonly seen in children between 1-2 years of age. It is characterised by enlarged lymphnodes, spleen and liver. Lab findings includes thrombocytopenia, leukocyte count lower than classic CML, and in increase in propoion of fetal hemoglobin.
3
Thrombocytopenia
Lymphadenopathy
Presence of Philedelphia chromosome
High HbF
Medicine
null
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Maximum cones are seen in
Optic disc, 1.5 mm in size, is responsible for blind spot of Mariotte Rods and cones are sensory end organs of vision Rods are absent in the foveal region. Ganglion cell layer is thickest in the macular region. Foveola is the most sensitive pa of retina. It contains only cones and their nuclei covered by a thin internal limiting membrane. There are 3 types of cones Red (maximum number) 65% Green Blue (least number) Cones are packed and tight mosaic hexagonal cells Visual acuity depends upon the density of cone mosaic
2
Limbus
Fovea centralis
Macula lutea
Blind spot
Ophthalmology
Retina
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The term metaplasia refers to
null
3
Irregular, atypical proliferative changes in epithelial or mesenchymal cells
Loss of cell substance producing shrinkage of the cells
Replacement of one type of adult cell by another type of adult cell
None of the above
Pathology
null
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multi
Hypoglycemic unawareness that occurs in diabetic patients when transferred from oral hypoglycemics to insulin, is due to :
Answer is A (Autonomic neuropathy): Hypoglycemic unawareness refers to a loss of warning symptoms that ale individuals to the presence of hypoglycemia and prompt them to eat and'abo the episode. Hypoglycemic unawareness can be attributed to two factors : Autonomic neuropathy Loss of catecholamine response to hypoglycemia : This means that patients with repeated attacks of hypoglycemia lose their capacity to release epinephrine and norepinephrine in response to hypoglycemia. (increase release of glucogon in response to hypoglycemia is lost very early in type I Diabetes Thus type I patients overeated with insulin may be unaware of critically low levels of blood glucose because of an adaptive blunting of their alarm systems owing to repeated episodes of hypoglycemia.
1
Autonomic neuropathy
Insulin resistance
Lipodystrophy
Somogi phenomenon
Medicine
null
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True about Epidural anesthesia – a) Effects start immediatelyb) C/I in coagulopathiesc) Given in subarachnoid spaced) Venous return decreases
Epidural anesthesia is given outside the dura in epidural (extradural) space (not in subarachnoid space). Onset of effect takes place in 15-30 minutes (not immediately). In contrast, spinal anesthesia has immediate effect (approximately 5 minutes). Neuraxial block (spinal & epidural) anesthesia is contraindicated in coagulopathy or bleeding diasthesis. Neuraxial block (spinal & epidural) can cause venous pooling and decreased venous return.
1
bd
d
ab
ac
Anaesthesia
null
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multi
A boil is due to staphylococcal infection of -
• Folliculitis, carbuncles and furuncles are all types of localized (superficial) skin infections that fall under the category of boils. • Hair follicles serve as portals for a number of bacteria, although S. aureus is the MC cause of localized folliculitis.
1
Hair follicle
Sweat gland
Subcutaneous tissue
Epidermis
Surgery
null
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A 14-year-old boy has difficulty in expressing himself in writing and makes frequent spelling mistakes, does not follow instructions and cannot wait for his turn while playing a game. He is likely to be suffering from
Specific Learning Disability (SLD) in youth is a neurodevelopmental disorderproduced by the interaction of heritable and environmental factors that influence the brain's ability to effeciently perceive or process verbal and non verbal information. It is characterised by persistent difficulty learning academic skills reading, written expression, that is inconsistent with the overall intellectual ability of a child. They find difficulty to keep up with their peers in ceain academic subjects. SLD is associated with an increased risk of comorbid disorders, including ADHD, Communication disorders, Conduct disorders and Depressive disorders. Ref: Synopsis of Psychiatry, 11e, pg 1181.
3
Mental retardation
Lack of interest in studies
Specific learning disability
Examination anxiety
Psychiatry
Child psychiatry
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single
The cone of tissue removed in the operation of conization consists of :
A+B
4
All the racemose glands
Eroded area of the cervix
Some of the racemose glands
A+B
Gynaecology & Obstetrics
null
34213afc-2831-42bc-a54e-7372c286bbef
multi
Which is not transmitted through blood -
Ans. is 'b' i.e., CholeraInfections transmitted by bloodViralBacterialParasiteso HCVo Pseudomonaso Taxoplasmao HBVo Yersiniao Malariao HIVo Coagulase negative stapho Babesiao CMVo Borrefia burgdorferio Chagas dis.o HTL V - Type 1(Lyme dis) o Hepatitis G virus (GBV-C) o Parvovirus B-19 o Hepatitis A (rarely) o West Nile virus o Creutzfeld - Jakob dis.
2
Westnile
Cholera
Toxoplama
HBV
Social & Preventive Medicine
Cholera
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single
A 29year old primigravida at 36weeks with Rh negative pregnancy came to labor room with complaints of bleeding per vaginum followed by abdominal trauma. Which of the following test is advised to estimate the size of fetomaternal haemorrhage?
* kliehauer Betke test is the procedure of choice to assess the volume of the fetal maternal bleeding * It should be done as soon as possible (within 2hours) after delivery in women with suspected large feto maternal haemorrhage who need larger amounts of anti D * This method is based on the fact that an acid solution elutes the adult but not the fetal hemoglobin from the red cells. * Fetal erythrocytes appear in a smear stained dark red and surrounded by colourless ghosts that are adult erythrocytes without hemoglobin. * This test can detect as little as 0.2ml of fetal blood diluted in 5litres of maternal blood. * Following clinical scenarios are associated with large feto maternal bleeding: 1. Traumatic deliveries including cesarean 2. Manual removal of placenta 3. Still bihs and intrauterine deaths 4. Abdominal trauma during the third trimester 4. Twin pregnancies at delivery 5. unexplained hydrops fetalis Reference: Greentop guidelines no: 22
2
Rosette test
Kliehaure acid elution test
Indirect coombs test
Middle cerebral aery peak systolic velocity
Gynaecology & Obstetrics
Medical, surgical and gynaecological illness complicating pregnancy
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A hemodynamically stable patient with blunt abdominal trauma, the best investigation is ?
CT Scan of Abdomen: It is most commonly used and better investigation for abdominal trauma. It is useful in blunt/penetrating trauma, suspected pancreas, spleen, liver, duodenal, retroperitoneal injuries. Smaller injuries, early haemoperitoneum are better detected. It is noninvasive, highly specifi c, highly accurate (96%), with low false-positive/low false-negative, noninvasive. Diagnostic Peritoneal Lavage (DPL) (by Perry) It is useful in blunt injury abdomen. It is not very useful in penetrating injury, bowel injury, retroperitoneal and pelvic injuries. Focused abdominal sonar trauma (FAST): It is rapid, noninvasive, poable bedside method of investigation focusing on pericardium, splenic, hepatic and pelvic areas. It is not reliable for bowel or penetrating injuries. It often needs to be repeated. SRB's Manual of Surgery, 4th Edition, pg. no. 150
1
CECT abdomen
MRI abdomen
DPL
FAST
Surgery
Trauma
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Which of the following radio of Iodine is used for thyroid scan: September 2008
Ans. A: 1-123 The radionuclides that are used in thyroid scans are two isotopes of iodine, 1-131 and 1-123, and an isotope of technetium known as 99m Tc. Technetium scanning is preferred for some diagnostic workups because it is relatively fast and does not require the patient to fast beforehand. Many prefer to reserve 1-131 for follow-up evaluations of cancer patients, and use 1-123 for thyroid uptake tests and routine thyroid scans. The reason for the distinction is the higher radiation burden of 1-131.
1
1-123
1-125
1-127
1-131
Radiology
null
95b9e1f5-eca3-443a-81bf-9ab7c9845218
single
Which of the following is not a suprahyoid space?
Ans. is'c'i.e., Anterior visceral spaceRef: Ballenger's Otorhinolaryngology: Heat and Neck Surgery 1//e by james Byron Snow, Phillip A. Wackym, John lacob Ballenger p. 1021, Cummings Otolaryngology- Head and Neck Surgery Sh/e, Ch. 14Suprahyoid neckThese spaces are :-Peritonsillar spaceSubmandibular 6 sublingual spacesPrestyloid parapharyngeal spaceMasticator spaceParotid space
3
Masticator space
Peritonsillar space
Anterior visceral space
Parapharyngeal space
ENT
null
06133f6a-acde-4586-89df-16918c2f4742
single
Doxycycline is used in the treatment of following disease except:
TETRACYCLINES These are a class of antibiotics having a nucleus of four cyclic rings. The tetracyclines still available in India for clinical use are: Tetracycline Oxytetracycline Demeclocycline Doxycycline Minocycline Uses: Although tetracyclines are broad-spectrum antibiotics, they should be employed only for those infections for which a more selective and less toxic AMA is not available. Clinical use of tetracyclines has very much declined due to availability of fluoroquinolones and other efficacious AMAs. USES: >Mild leptospirosis is treated with doxycycline, ampicillin, or amoxicillin. For severe leptospirosis, intravenous penicillin G has long been the drug of choice, although the third-generation cephalosporins cefotaxime and ceftriaxone have become widely used. >Rickettsial infections: typhus, rocky mountain spotted fever, Q fever, etc. respond dramatically. Chloramphenicol is an alternative. >Relapsing fever* due to Borrelia recurrentis responds adequately ESSENTIALS OF MEDICAL PHARMACOLOGY, www.medscape.com K.D.TRIPATHI SIXTH EDITION PAGE NO:715
4
Leptopirosis
Q fever
Borreliosis
All of the above
Pharmacology
Chemotherapy
fdef2d77-b02e-41aa-9b8a-3c5a97e1c591
multi
External cephalic version is contraindicated in all except: March 2012
Ans: D i.e. Breech presentation Indications for external cephalic version are breech presentation & transverse lie.
4
Antepaum haemorrhage
Multiple pregnancy
Contracted pelvis
Breech presentation
Gynaecology & Obstetrics
null
57d9a425-4234-4979-8f15-3a6b33e2a8fe
multi
Which of the following is/are the side effect/s of using argon laser -
argon gases causes all d side effects. REF:khurana,pg no 461
4
Hypopigmentation
Crusting
Keloid formation
All the above
Ophthalmology
Miscellaneous
c1e0ee54-a122-4e6f-a2c5-e8dd8ef83370
multi
Number of amino acids in A chain and B chain of insulin is:
Ans: d (21 and 30) Ref: Vasudevan,4th ed, p. 108Insulin is a protein hormone with 2 polypeptide chains; the A chain with 21 amino acids and B chain with 30 amino acids.Insulin:T 1/2 of insulin is 5 minutes.Normal daily insulin secretion is 50 units.Tissues independant of insulin - RBC, brain, renal medullary cells, placenta.Amino acids stimulating insulin secretion - leucine and arginine.Pork insulin differs from human insulin by only one amino acid residue.
4
30, 21
28, 32
32, 28
21, 30
Biochemistry
Proteins and Amino Acids
b91295f2-73f4-480c-b601-d23a111fe730
single
The macrophage to epitheliod conversion in Mycobacterium tuberculosis infection is mediated by:
Ref: Robbins Pathologic Basis of Disease, 8th edition, Pg: 183Explanation:T Cell-Mediated (Type IV) HypersensitivityThe cell-mediated type of hypersensitivity is initiated by antigen-activated (sensitized T lymphocytes, including CD4+ and CD8+ Tcells.Tubercle bacilli colonizing the lungs are persistent or nondegradable antigensThe perivascular infiltrate is dominated by macrophages over a period of 2 or 3 weeks.The activated macrophages often undergo a morphologic transformation into epithelium-like cells and are then referred to as epithelioid cells.A microscopic aggregation of epithelioid cells, usually surrounded by a collar of lymphocytes, is referred to as a granuloma.This pattern of inflammation, called granulomatous inflammation is typically associated with strong T-cell activation with cytokine production.M. tuberculosis enters macrophages by endocytosis mediated by several macrophage receptors: mannose receptors bind lipoarabino- mannan. a glvcolipid in the bacterial cell wall, and complement receptors bind opsonized mycobacteria.M. tuberculosis organisms replicate within the phagosome by blocking fusion of the phagosome and lysosomeAbout 3 weeks after infection, a T-helper 1 (TH1) response is mounted that activates macrophages to become bactericidal.Differentiation of TH1 cells depends on IL-12, which is produced by antigen-presenting cells that have encountered the mycobacteria.Mature TH1 cells, both in lymph nodes and in the lung, produce IFN-g.INF-g is the critical mediator that enables macrophages to contain the M. tuberculosis infection.IFN-g stimulates formation of the phagolysosome in infected macrophages, exposing the bacteria to an inhospitable acidic environment.Macrophages activated by IFN-y differentiate into the "epithelioid histiocytes" that characterize the granulomatous response, and may fuse to form giant cells.Activated macrophages also secrete TNF. which promotes recruitment of more monocytes.
2
TNF alpha
IFN-g
IL-4
TGF-Beia
Pathology
Cells and Tissues of Immune System
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single
An 18-year-old girl presents with amenorrhoea, milk discharge, weight loss. Diagnosis is
Its tempting here to go for Hypothyroidism but that is usually associated with weight gain. However, pituitary tumors and craniopharyngiomas can cause increase in PRL and consequent galactorrhea , weight loss attributed then to the malignant process. Ref - Harrison 20e pg2673
1
Pituitary Cancer
Anorexia nervosa
Hypothyroidism
Hypothalamic cause
Medicine
All India exam
ac2b2c6f-6c24-4117-a0b0-02c0241aec10
single
Which of the following is NOT a prodrug ?
null
2
Enalapril
Imipramine
Sulphasalazine
Cyclophosphamide
Pharmacology
null
169ce8e3-9f61-45f6-abc3-49ee2e8573d4
single
Clavipectoral fascia is derived from which ligament
CLAVIPECTORAL FASCIAStrong fascial sheet deep to clavicular head of pectoralis major muscle.Fills space between clavicle and pectoralis major.Extend:-Verically-clavicle above to axillary fascia below.Medially-first rib and costoclavicular ligament.Laterally- coracoid process and blends with coracoclavicular ligament.The thick upper pa of fascia extending from first rib near costochondral junction to the coracoid process is called costocoracoid ligament.Clavipectoral fascia encloses two muscles- subclavius and pectoralis major.Structures piercing:-1. Thoracoacromial aery 2. Apical group of axillary lymph nodes.3. Lateral pectoral nerve.4. Cephalic vein{Reference: Vishram Singh, pg no.43}
4
Coracoacromial
Coracoclavicular
Costoclavicular
Costocoracoid
Anatomy
Upper limb
3807f643-9fdb-40df-8e36-dd34b1545d5f
single
The following are indications for assisted ventilation in acute severe asthma EXCEPT?
PEFR of 50-60% indicates moderate asthma. Indication for intubation in asthma exacerbation is a poor response to oxygen with salbutamol nebulisation and oral steroids. The definition of poor response is: 1. FEV1< 40%. 2. PaCO2> 45mmHg. 3. Features of carbon dioxide narcosis. 4. Hypoxia defined as PaO2<60 mm Hg.
1
PEFR 50-60% of predicted value
Rising PaCO2> 6kPa (45 mm Hg)
Diminishing level of consciousness
Falling PaO2< 8kPa (60 mm Hg)
Medicine
COPD and Asthma
f567a9a3-e1a0-4765-86f2-f2e2f7b22a8d
multi
All of the following are causes of vasogenic type of cerebral edema except
Vasogenic edema occurs due to a breakdown of the tight endothelial junctions that make up the blood-brain barrier. This allows intravascular proteins and fluid to penetrate into the parenchymal extracellular space. Some premature babies have bleeding in the brain, which can block the flow of CSF andcause hydrocephalus. Other possible causesof congenital hydrocephalus include: X-linked hydrocephalus - caused by a mutation of the X chromosome Ref ganong's review of medical physiology 25e p277
4
Tumours
Trauma
Infections
Hydrocephalus
Physiology
All India exam
7e74efbc-80b5-4366-a286-3898e7c512ee
multi
The ovarian cycle is initiated by:
Ans. is a i.e. FSHRef: Shaw 14th/ed, p41, Dutta Gynae 5th/ed, p82Ovarian cycle is initiated by FSHRemember: Following questions asked, previously on FSHFSHi. It is the hormone which initiates ovarian cycleii. In menopausal females- Since primordial follicles are decreased so levels of estrogen is decreased, so negative feedback on FSH is decreased, hence levels of FSH are increased and increased FSH levels are a sine qua non of menopause.iii. Human menopausal gonadotropin (HMG) is FSH and LH obtained from the urine of postmenopausal femalesiv. FSH levels can help in differentiating the causes of male infertility vizIn pretesticular cause of male infertility = FSH decreasesIn testicular cause = FSH levels increaseIn post testicular cause = FSH is normal
1
FSH
Estrogen
LH
Progesterone
Gynaecology & Obstetrics
Physiology & Histology
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single
All of the following cephalosporins have good activity against Pseudomonas aeruginosa except ?
Ans. is 'a' i.e., Cephadroxil o Cephalosporins with antipseudomonal activity :- Ceftazidime, Cefoperazone, Cefepime
1
Cephadroxil
Cefepime
Cefoperazone
Ceftazidime
Pharmacology
null
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multi
A young woman is evaluated by a neurosurgeon because of injuries she received in an explosion. She has numerous lacerations of the front and back torso and bruising of the craniofacial region. Neurological examination shows lack of movement in her right lower extremity with hyperreflexia, and loss of proprioception and fine touch in this extremity, but pain and temperature sensation are intact. Pain and temperature sensation are absent in the left lower limb. Movement and reflexes are normal in the left lower extremity and upper extremities. A lesion in which of the following locations can explain her neurological examination?
null
3
Hemisection of the left side of the spinal cord at the level of the first lumbar segment of the cord
Hemisection of the left side of the spinal cord at the level of the fourth sacral segment of the cord
Hemisection of the right side of the spinal cord at the level of the first lumbar segment of the cord
Hemisection of the right side of the spinal cord at the level of the fourth sacral segment of the cord
Medicine
null
44341437-ae7e-4870-abcb-f00512b464b8
single
Structure damaged most commonly during Surgery on Ranula is?
Submandibular duct REF: Clinical surgery: Volume 9 Head and neck edited by Charles Rob, Rodney, Smith page 56 "The treatment of ranula constitutes a problem, owing to the technical difficulty of complete excision without damage to adjacent structures such as the submandibular duct"
3
Lingual Aery
Lingual Nerve
Submandibular duct
Sublingual duct
Surgery
null
27c4dfce-2bf3-4c5e-951c-8f947eda667a
single
Puppe's rule deals with?
Ans. is `b' i.e., Multiple impact injuries
2
Chemical injuries
Multiple impact injuries
Sexual assault
Percentage of burns
Forensic Medicine
null
1e11b518-54c2-488f-9ead-f405ee1a2efe
single
NOT a content of carpal tunnel
Carpal tunnel Contents - 1. 4 tendons of Flexor Digitorum Profundus (FDP) 2. 4 tendons of Flexor Digitorum Superficialis (FDS) 3. 4 tendons of Flexor Pollicis Longus (FPL) 4. Median nerve Structure passing anterior to carpal tunnel: 1. Ulnar nerve 2. Ulnar aery 3. Palmaris longus tendon. Structure embedded into flexor retinaculum Flexor carpi radialis tendon.
3
Flexor pollicis longus
Flexor digitorum profundus
Ulnar nerve
Median nerve
Anatomy
FMGE 2018
ce5819fd-1e86-480a-8c90-240395fe21f1
single
Sensitivity is a measure of
(A) True positive # Term Sensitivity was introduced by Yarushalmy in 1940s as a statistical index of diagnostic accuracy.> It has been defined as the ability of a test to identify correctly all those who have the disease, that is "True positive".> A 90% sensitivity means that 90% of the diseased people screened by the test will give a "true positive" result and remaining 10% a "false negative" result.> Sensitivity has been defined as the ability of a test to identify correctly all those who have the disease, that is "true positive".> Sensitivity: the ability of a test to identify correctly all those who have the disease, i.e. true positive ... a/a + c x 100> Specificity: The ability of a test to identify correctly those who do not have the disease i.e. true negative ...d/(b+d) x 100
1
True positive
False positive
True negative
False negative
Social & Preventive Medicine
Miscellaneous
38d8900f-3c53-49b8-b9e8-f498c9276949
multi
OPV Bivalent vaccine contain:
b. P1 & P3(Ref: Nelson's 20/e p 1561, 3212, Ghai 8/e p 190-194)Monovalent OPVs (mOPVs) & bivalent OPV (bOPV) are 2.5-3 times more efficacious than trivalent OPVIn bivalent OPV, the type 2 component is removed
2
P1 & P2
PI & P3
P2 & P3
P1, P2 & P3
Pediatrics
Immunization
afcc1975-d4b8-43fd-a8d7-10473455f957
single
Which of the following enzymes does NOT contain Zn? (NOT RELATED)
Zinc is required for the activity of > 300 enzymes, covering all six classes of enzymes. alcohol dehydrogenase; superoxide dismutase; transferases like RNA polymerase and aspaate transcarbamoylase; hydrolases like carboxypeptidase A and thermolysin; lyases like carbonic anhydrase and fructose-1,6-bisphosphate aldolase; isomerases like phosphomannose isomerase; and ligases like pyruvate carboxylase and aminoacyl-tRNA synthases
2
Alcohol Dehydrogenase
Arginase
Alkaline Phosphatase
Carbonic Anhydrase
Pharmacology
All India exam
c61d6422-b2f9-436a-9123-0ab8ba50ff77
single
A patient presents with vomiting and severe colicky abdominal pain. He underwent bariatric surgery 5 years ago. He is advised to undergo an emergency reoperation. Which of the following procedures did he most likely undergo 5 years ago?
Patient must have underwent Laparoscopic Roux-en-Y gastric bypass 5 years ago Now presented with internal hernia- late complication of gastric bypass surgery Closure of hernia defects at the time of gastric bypass surgery reduces the incidence of symptomatic internal hernias in future.
1
Laparoscopic Roux-en-Y gastric bypass
Laparoscopic adjustable gastric banding
Sleeve gastrectomy
Biliopancreatic division
Surgery
Robotics, Laparoscopy and Bariatric Surgery
51b5232f-876b-4b6e-8958-8c32f4b1d1fd
single
Reese-Ellsworth classification is used for?
ANSWER: (B) RetinoblastomaREF: Decision Making in Radiation Oncology, Volume 2 by Jiade J. Lu page 1041Repeat from June 2008Reese-Ellsworth classification of Retinoblastoma:TypeDescriptionGroup I"Very favourable"ASolitary tumor, less than 4 dd in size, at or posterior to the equatorBMultiple tumors, none over 4 dd in size, all at or posterior to the equatorGroup II"Favourable"ASolitary tumor, 4-10 dd in size, at or posterior to the equatorBMultiple tumors, 4-10 dd in size, all posterior to the equatorGroup III"Doubtful"AAny lesion anterior to the equatorBSolitary tumors larger than 10 dd posterior to the equatorGroup IV"Unfavorable"AMultiple tumors, some larger than 10 ddBAny lesion extending to the ora serrataGroup V"Very unfavourable"AMassive tumors involving over half the retinaBVitreous seeding*dd= disc diameter (approximately 1.5 mm)
2
Rhabdomyosarcoma
Retinoblastoma
Optic nerve sheath tumor
Meningioma
Ophthalmology
Intra Ocular Tumour
7742f99f-5e9e-49d5-a160-1aa3d993a4a4
single
Which of the following is an indication for the use of folinic acid?
Prophylaxis of neural tube defects require treatment with folic acid. Methotrexate toxicity can be prevented by 5'-formyltetrahydrofolate (folinic acid). Pernicious anemia requires the therapy with vitamin B12. Anemia associated with chronic renal failure is treated with erythropoietin.
2
Prophylaxis of neural tube defects in the offspring of women receiving anticonvulsant medications
Counteracting toxicity of high dose methotrexate therapy
Pernicious anemia
Anemia associated with renal failure
Pharmacology
Hematology
50cbb188-7d62-40e1-bfca-b31cf71c5557
single
Narcotic overdose can be antagonized by
null
3
Diphenhydramine
Atropine
Naloxane
Nalorphine
Pharmacology
null
b3038faa-8f83-4755-9c88-1e29de6ddcc0
single
True about lupus anticoagulant include the following except -
null
1
Bleeding episodes can be life threatening
↑aPTT
May occur without clinical signs
May be associated with recurrent mid trimester abortions
Medicine
null
9ceb42cd-ae64-4d96-99dd-88115a3ac368
multi
Patient presents with varicose vein with sapheno-femoral incompetence and normal perforator. Management options include all of the following except
Ans. b. Sclerotherapy
2
Endovascular stripping
Sclerotherapy
Sapheno-femoral flush ligation
Saphenofemoral flush ligation with striping
Surgery
null
804c99cc-b1d1-4834-be32-5770d869e0cc
multi
Neuro surgical intervention may be necessitated in all of the following Except
Diffuse axonal injury (DAI) is a form of traumatic brain injury. It happens when the brain rapidly shifts inside the skull as an injury is occurring. The long connecting fibers in the brain called axons are sheared as the brain rapidly accelerates and decelerates inside the hard bone of the skull. DAI typically causes injury to many pa of the brain, and people who suffer a DAI are usually left in a coma. The changes in the brain are often very tiny and can be difficult to detect using CT or MRI scans. It is one of the most common types of traumatic brain injury and also one of the most devastating. The prevailing symptom of DAI is loss of consciousness. This typically lasts six or more hours. If the DAI is mild, then people might remain conscious but display other signs of brain damage. These symptoms can be extremely varied, as they depend upon which area of the brain has been damaged. They can include: disorientation or confusion headache nausea or vomiting drowsiness or fatigue trouble sleeping sleeping longer than normal loss of balance or dizziness Ref:
4
SDH
EDH
Depressed fracture
Diffuse axonal injury
Surgery
Trauma
96d3bdac-dfa2-4da6-ac8c-1e67cd06b442
multi
Subclan aery is divided by which muscle ?
Ans. is 'c' i.e., Scaleneus anterior Scaleneus anterior muscle divides subclan aery into three pas :?A) First pa :This pa is medial (proximal) to scaleneus anterior. Branches from first pa are :?Veebral aeryInternal thoracic aeryThyrocervical trunk:Costocervical trunk (on left side only).B) Second pa :This pa lies posterior to scalenus anterior. It gives origin to Costocervical trunk on right side. Costocervical trunk gives following branches:Deep cervical aerysuperior intercostal aery.C) Third pa :This pa lies lateral (distal) to scalenus anterior. It gives dorsal scapular aery (sometimes dorsal scapular aery arises from transverse cervical aery, a branch of thyrocervical trunk).
3
Pectoralis minor
Teres minor
Scaleneus anterior
Trapezius
Anatomy
null
2aed5043-026a-4c5f-99a8-44de1610e0e4
single
NICE project is associated with:
National Institute of Social Defence has launched NICE project (National Initiative on Care for Elderly) in 2000. Ref: National Health Programmes in India, J.Kishore, 10th edition pg: 795
4
Female literacy
Population control
Rural infrastructure
Care of elderly
Social & Preventive Medicine
null
98008e16-5448-4ec6-bb50-a86d7a5a1cd1
single
Commonest feature of hypothyroidism in children is
Ans. is 'c' i.e., Cold extremities o Amongst the given options cold extremities is the best answer. o Prolongation of physiological jaundice is the earliest sign.
3
Cataract
Recurrent seizures
Cold extremities
Laryngospasms
Pediatrics
null
d17a2408-d240-411b-9193-c7ef57a14cd8
single
Left medial sector contains segment
Left medial sector contains segment III and IV Left lateral sector contains only one segment II Ref: Sabiston 20th edition Pgno : 1421-1422
1
III, IV
II, III
I, II
I, IV
Surgery
G.I.T
c92e770d-f617-4ace-81f2-d9f714a644cd
single
The medicolegal importance of postmortem lividity is all except -
Medicolegal importance of postmortem staining are :- It is a sign of death. Helps to know time since death. Helps to know the position or posture of dead body. Sometimes cause of death can be known by peculiar distribution, e.g. in hanging or drowning.
3
Cause of death elsewhere
Time since death
Manner of death
Position of the body at the death
Forensic Medicine
null
3d6bdc12-7262-4610-b54a-8544fae0ca3f
multi
Saffron coloured meconium is seen in:
Postmaturity syndrome is the description of a clinical syndrome in which fetus experiences placental insufficiency and resultant growth restrictions.The classical syndrome describes a neonate with wrinkled ,peeling skin coated with meconium,overgrown nails ,well developed palm and sole creases ,reduced subcutaneous fat and a wizened old man appearance (refer pgno:218 sheila textbooks of obstetrics 2 nd edition)
1
Postmaturity
TB
Breech
Normal in appearance
Gynaecology & Obstetrics
Abnormal labor
6c0a6ec2-4847-4874-8737-61de579f48c1
single
First change of improvement noted after iron therapy is initiated
First change of improvement noted after iron therapy is decreased irritability followed by increased reticulocyte count. Reference: GHAI Essential pediatrics, 8th edition
1
Decreased irritability
Reticulcytosis
Increase in serum iron levels
Replenishment of iron stores
Pediatrics
Hematology
a937600a-0f2d-47a7-a689-e2792d77b580
single
Expectant management of placenta pre includes all except
The regimen advocated by Macafee Carried out in a teiary care Complete bed rest with bedside toilet facilities Anaemia has to be looked for and corrected by blood transfusion Iron ,vitamins,calcium should be continued Antenatal steroids can be given to promote lung maturity Anti -D should be given (refer pgno: 132 sheila 2 nd nd edition)
2
Anti-D
Cervical encirclage
Blood transfusion
Steroids
Gynaecology & Obstetrics
General obstetrics
20b3516d-80f0-44f4-852c-0fa3c1670cde
multi
Which of the following enzyme leads to release of free glucose from glycogen during glycogenolysis in muscle?
Debranching enzyme Has 2 catalytic sites in a single polypeptide chain. Glucan transferase and debranching enzyme are the two separate activities of the same enzyme. Glucan transferase 1,6-glycosidase transfers a trisaccharide unit from one branch to the other, exposing the 1 - 6 branch point. Breaks a (1- 6) bond, which is present at the staing of a branched-chain releasing glucose **Glucose-6-phosphatase also release free glucose but only in liver and not in muscle.
4
Glycogen phosphorylase
Glucose-1-phosphatase
Glucose-6-phosphatase
Debranching enzyme
Biochemistry
Glycogen
09a40c4d-2b66-4ae6-acf6-443a34cb19ac
single
Which of the following tumours present with proptosis?
PROPTOSIS It is defined as forward displacement of the eyeball beyond the orbital margins. Causes of bilateral proptosis include: Tumours: These include symmetrical lymphoma or lymphosarcoma, secondaries from neuroblastoma, nephroblastoma, Ewing's sarcoma and leukaemic infiltration. Ref:- A K KHURANA; pg num:-379,381
4
Nephroblastoma
Neuroblastoma
Ewings sarcoma
All of the above
Ophthalmology
Tumors
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multi
Macula is stimulated by
Macula senses the position of the head in response to gravity and linear acceleration. Ref: Diseases of EAR, NOSE and THROAT by PL Dhingra; 6th edition; page no.16
4
Gravity
Head position change
Linear acceleration
All of the above
ENT
Ear
f5f95c8a-b956-40e0-b1ae-11cc0af53ce7
multi
Skin scrapings from a patient with tinea corporis were taken and cultured on SDA. Figure shows the LCB mount. Likely identity of the causative dermatophyte is-
M. gypseum-numerous fusiform (spindle) shaped macroconida M. audouinii- racquet shaped macroconidia E. floccosum- club shaped macroconidia T. rubrum- arrangement of microconida has been described as "birds on a wire" where the pyriform (teardrop shaped) microconidia are attached to the hyphae at the narrow end
3
Epidermophyton floccosum
Microsporum audouinii
Microsporum gypseum
Trichophyton rubrum
Microbiology
Mycology
ec307ba8-8ac8-46d7-bcbd-d079a356295d
single
The term 'myopia' refers to:
null
1
Near sightedness
Far sightedness
Constriction of the pupil
Dilation of the pupil
Physiology
null
f4a6101c-25ad-47dc-a271-9634d02ae4b6
single
Karsakoff's Psychosis is diagnosed by
C i.e. Impairment of long term memory
3
Peripheral neuropathy
Visual hallucination
Impairment of long term memory
Seizures
Psychiatry
null
471e624d-df78-4858-914f-c142138a2b27
multi
Toxicity of leigonella is due to:
Toxin
2
Capsule
Toxin
Phage
Plasmid
Microbiology
null
08f8032e-01cd-4799-b05c-99d1cc75f844
single
Best method of treatment of Methyl alcohol -
Among the given options only ethyl alcohol is used.
2
Calcium gluconate
Ethyl alcohol
Amphetamines
1% Ammonia
Forensic Medicine
null
21bea5f2-11e6-47a5-95ac-25ba2c5b97c2
single
Carcinoma cervix extends to the lateral pelvic wall in which stage
Stage III B more precisely. Ref mudaliar textbook of obstetrics 6e p561
2
Stage I
Stage II
Stage III
Stage IV
Physiology
All India exam
b5f8b60e-f28b-4fdb-b1dc-b48ce8b64689
multi
Most common site of curling's ulcer?
Ans. (a) Proximal duodenum(Ref: Robbins 9th/pg 762)Curling ulcers-Ulcers occurring in the proximal duodenum and associated with severe burns or trauma
1
Proximal Duodenum
Esophagus
Distal duodenum
D. jujenum
Pathology
G.I.T.
d38cf328-624f-4732-86ce-0cf65abfed6e
single
In Budd Chiari syndrome, the site of venous thrombosis is
null
3
Infrahepatic inferior vena cava
Infrarenal inferior vena cava
Hepatic veins
Portal veins
Medicine
null
3c22d179-3339-4aaf-9835-463ba3be0078
single
Parenchymatous xerosis of conjunctivitis is caused by
A i.e. Trachoma Vit A deficiency causes epithelial xerosisQ. Parenchymal xerosis is caused by widespread destructive interstitial conjunctivitis as seen in trachoma Q, diptheria, Steven Jonson Syndrome, pemphigus or pemphigoid conjunctivitis, thermal, chemical or radiational burns of conjunctiva Q and exposure of conjunctiva.
1
Trachoma
Vitamin A deficiency
Vernal catarrh
Phlyctenular keratoconjunctivitis
Ophthalmology
null
8457564e-ce71-4f98-9817-f32509607540
single
Treatment for impetigo ?
Ans. is 'a' i.e., Dicloxacillin Treatment of impetigo is either dicloxacillin or cephalexin can be given at a dose of 250 mg four times daily for 10 days. Topical mupirocin ointment is also effective.
1
Dicloxacillin
Ciprofloxacin
Gentamycin
Amoxicillin and clavulanic acid
Pharmacology
null
791736f2-e882-4183-9774-0fcf99347c85
single
A patient operated for thyroid surgery for a thyroid swelling, later in the evening developed difficulty in breathing. There was swelling in the neck. The immediate management would be
Haemorrhage is the most frequent life-threatening complication of thyroidectomy. Around 1 in 50 patients will develop a haematoma, and in almost all cases this will develop in the first 24 hours. If an aerial bleed occurs, the tension in the central compament pressure can rise until it exceeds venous pressure. Venous oedema of the larynx can then develop and cause airway obstruction leading to death. If a haematoma develops, clinical staff should know to remove skin sutures in order to release some pressure and seek senior advice immediately. Endotracheal intubation should be used to secure the airway while the haematoma is evacuated and the bleeding point controlled.Ref: Bailey and Love, page no: 815
4
Epinephrine injection
Tracheostomy
IV calcium gluconate
Open the wound sutures in the ward
Surgery
Endocrinology and breast
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single
Line of surgical divison of the lobes of the liver is -
null
2
Falciform ligament to the diaphragm
Gall bladder bed to IVC
Gall bladder bed to the Lt crus of diaphragm
One inch to the left of falciform ligament to the IVC
Surgery
null
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multi
Developmental Quotient is calculated as:
Ans. A. Average age at attainment/observed age at attainment x100Significant delays on screening is an indication for a detailed formal assessment of developmental status. By assessment, one can assign developmental quotient (DQ) for any developmental sphere. A DQ below 70 is taken as delay
1
Average age at attainment / observed age at attainment x100
Observed age at attainment / average at attainment x100
Observed age at attainment x average age at attainment
Observed age at attainment / average age at attainment
Pediatrics
Growth, Development, and Behavior
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single
Temperomandibular joint is:
Temporo-mandibular joint is weight-bearing joint though not covered by hyaline cartilage like sterno-clavicular joint. Clavicle ossifies at five weeks followed by mandible at six weeks. Absence of hyaline cartilage is because no cartilaginous precursor exists at that time. This does not mean that the joint is non-weight bearing, it is the early ossification which has made the joint free of hyaline cartilage.
4
Devoid of the synovial membrane.
Has no synovial fluid.
Has rudimentary synovial membrane.
The synovial membrane does not cover the articular surface.
Dental
null
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single
Which of the following ranges of haemoglobin O2 saturation from systemic venous to systemic aerial blood represents a normal resting condition?
In a normal res ng condition, the blood leaving the lungs is 98% saturated with oxygen, and the blood returning to the lungs is 75% saturated with oxygen. With vigorous exercise, blood leaving the lungs is still 98% saturated, but blood returning is usually less than 75% saturated because more oxygen is unloaded from hemoglobin in exercising muscles
4
25 to 75%
40 to 75%
40 to 95%
75 to 98%
Pathology
All India exam
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single
Early deceleration pattern on cardiotocography indicates :
Head compression
1
Head compression
Fetal distress
Cord prolapse
Hypoxia
Gynaecology & Obstetrics
null
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single
False about Gaucher's disease
Three biochemical markers of gaucher disease Angiotensin-conveing enzyme ( ACE ) Tarate-resistant acid phosphate ( TRAP ) Chitotriosidase ( CHITO ) These marker are elevated in active disease, these are useful indicators of disease progress and response to enzyme replacement therapy So gaucher disease is basically Tarate-resistant acid phosphatase positive as the disease is being treated the levels of TRAP gradually declines
4
Beta Glucocerebrosidase defective
Cherry red spots on fundoscopy
Erlenmeyer's flask deformity
Tarate resistant acid phosphatase -ve
Physiology
All India exam
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multi
The pseudo-isomorphic phenomenon is seen in
Koebner response or the isomorphic response, attributed to Heinrich Kobner, is the appearance of skin lesions on lines of trauma. The Koebner phenomenon may result from either a linear exposure or irritation. Pseudokoebner phenomenon-Conditions demonstrating linear lesions after a linear exposure to a causative agent include molluscum contagiosum, was and toxicodendron dermatitis (dermatitis caused by a genus of plants including poison ivy). Was and molluscum contagiosum lesions can be spread in linear patterns by self-scratching ("auto-inoculation"). Toxicodendron dermatitis lesions are often linear from brushing up against the plant. True koebner phenomenon-Causes of the Koebner phenomenon that are secondary to scratching rather than an infective or chemical cause include vitiligo, psoriasis, lichen planus, lichen nitidus, pityriasis rubra pilaris, and keratosis follicularis Ref Harrison 20th edition pg 2111
4
Psoriasis
Lichen planus
Vitiligo
Molluscum contagiosum
Dental
All India exam
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single
Movement of protein from nucleus to cytoplasm can be seen by
B i.e. FRAPFRAP (fluorescence recovery after photobleaching) primarily measures rate of lateral diffusion of lipids and it can be used to investigate diffusion of biological macromolecules (such as proteins etc) including lateral diffusion in the plane of membrane and movements into & out of nucleus.- FRET is used to visualize biochemistry of living cells such as to measure cAMP and activity of PKA.AFM (atomic force microscopy) is used to yield 3D contour map of membrane (surfaces) and visualize membrane proteins (eg microdomains or rafts etc)
2
FISH
FRAP
Confocal microscopy
Electron microscopy
Biochemistry
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single
Sensitivity of a screening test indicates: September 2006
Ans. D: True positive
4
False positive
False negative
True negative
True positive
Social & Preventive Medicine
null
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multi
All are features of Alzheimer's disease except
Alzheimer's disease (AD), also referred to simply as Alzheimer's, is a chronic neurodegenerative disease that usually stas slowly and gradually worsens over time.It is the cause of 60-70% of cases of dementia. Gradually, bodily functions are lost, ultimately leading to death.[Although the speed of progression can vary, the typical life expectancy following diagnosis is three to nine years Stages of Alzheimer's disease Effects of ageing on memory but not AD Forgetting things occasionally Misplacing items sometimes Minor sho-term memory loss Not remembering exact details Early stage Alzheimer's Not remembering episodes of forgetfulness Forgets names of family or friends Changes may only be noticed by close friends or relatives Some confusion in situations outside the familiar Middle stage Alzheimer's Greater difficulty remembering recently learned information Deepening confusion in many circumstances Problems with sleep Trouble determining their location Late stage Alzheimer's Poor ability to think Problems speaking Repeats same conversations More abusive, anxious, or paranoid Ref Harrison20th edition pg 2667
2
Amyloid Angiopathy
Lewy bodies
Neurofibrillary tangles
Senile plaques
Medicine
C.N.S
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multi
Which of the following is the most specific and sensitive screening test in a case of renovascular hypertension -
null
4
HRCT
CT guided angiography
Captopril induced radionuclide scan
MRI
Medicine
null
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single
The Lipid which accumulates in fatty liver is
Fatty liver refers to the deposition of excess triglycerides in the liver cells. The balance between the factors causing fat deposition in liver versus factors causing removal of fat from liver determines the outcome.Causes of Fatty LiverA. Causes of fat deposition in liver1. Mobilization of NEFA from adipose tissue.2. Excess synthesis of fatty acid from glucose.B. Reduced removal of fat from liver3. Toxic injury to liver. Secretion of VLDL needs synthesis of apo B-100 and apo C.4. Decreased oxidation of fat by hepatic cells.An increase in factors (1) and (2) or a decrease in factors (3) and (4) will cause excessive accumulation, leading to fatty liver.Ref: DM Vasudevan - Textbook of Biochemistry, 6th edition, page no: 142
1
Trigylcerids
FFA
Lipoprotein
Cholesterol
Biochemistry
Metabolism of lipid
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