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Increased LH secretion just before ovulation is due to
Luteinizing hormone (LH) a gonadotropin of the anterior pituitary gland, acting with follicle-stimulating hormone to cause ovulation of mature follicles and secretion of estrogen by thecal and granulosa cells of the ovary; it is also concerned with corpus luteum formation. In the male, it stimulates development of the ...
2
Positive feed-back by progesterone
Positive feed-back by estrogen
Positive feed-back by FSH
Positive feed-bad by relaxin
Physiology
Endocrinology
6c521d0e-36e2-4bca-9ea8-5e6b7c892e89
single
The median of values 2, 5, 7, 10, 10, 13, 25 ?
Ans. is 'a' i.e., 10
1
10
13
25
5
Social & Preventive Medicine
null
5bfdd9aa-6acb-47a1-b4a8-3d2a1e90a88c
single
Salicylate intoxication is characterized by all of the following, EXCEPT:
Salicylate intoxication is associated with hypehermia and not hypothermia, as the drug causes uncoupling of oxidative phosphorylation, resulting in increased metabolism. Mild chronic salicylate intoxication is called salicylism. When fully developed, the syndrome includes headache, dizziness, tinnitus, difficulty heari...
3
Hyperventilation
Hypoprothrombinemia
Hypothermia
Metabolic acidosis
Pharmacology
null
a128844e-7602-43ee-a403-03f7bb51986b
multi
Which muscle causes opening of the upper end of esophagus?
Ans. is 'd' i.e., Cricopharyngeus of inferior constrictor Upper esophageal sphinctor* The upper esophageal sphincter surrounds the upper part of the esophagus.* It consists of skeletal muscle, but is not under voluntary control.* Opening of the upper esophageal sphincter is triggered by the swallowing reflex.* The prim...
4
Epiglottis
Thyropharungeus
Stylopharyngeus
Cricopharyngeus of inferior constrictor
Anatomy
Thorax
91927901-80be-47c6-a626-6b7e467b452d
single
Which of the following is the ego-expansion of JSY?
Janani Suraksha Yojana (JSY) • Launched on 12th April 2005 • It is a ‘modification of National Maternity Benefit Scheme • Objectives of JSY: Reduction of maternal mortality and infant mortality (through institutional deliveries and care especially for poor women.)
4
Janani Sampoorna Yojana
Janani Samridhi Yojana
Janani Swarojgar Yojana
Janani Surakshan Yojana
Social & Preventive Medicine
null
583d4688-0d95-443c-a6c7-316aa33d07a1
single
Drug used in refractory glaucoma ?
Ans. is 'c' i.e., Alpha agonist Drug of choice for initial treatment of open angle glaucoma is either an topical b-blocker or topical PG analogue (latanoprost) It target IOT is not attained either change over to alternative drug or use both concurrently. In refractory cases (who are not responding to (3-blockers and PG...
3
Systemic glucocoicoid
ACE inhibitor
Alpha agonist
Beta blocker
Ophthalmology
null
b6ec6bf2-fa70-477e-af00-d6cefeb451d1
single
A 10 year old boy has a fracture of femur. Biochemical evaluation revealed Hb 11.5 gm/dl and ESR 18 mm 1st hr. Serum calcium 12.8 mg/dL, serum phosphorus 2.3 mg/dL, alkaline phosphate 28 KA units and blood urea 32 mg/dL. Which of the following is the most probable diagnosis in his case-
Ans. is 'c' i.e., Hyperparathyroidism o You can solve the question just looking at calcium value. Amongst the given options only hyperparathyroidism causes hypercalcemia. The patient in question has an increased serum Ca', decreased serum phosphorus and increased values of alkaline phosphatase, all of which characteriz...
3
Nutritional rickets
Renal rickets
Hyperparathyroidism
Skeletal dysplasia
Pediatrics
null
10572939-fdef-490b-89f1-88597f5c4c2d
single
'Safe zone' of the eye ball is:
Ans. 8-9 mm behind the limbus
3
At the limbus
3-4 mm behind the limbus
8-9 mm behind the limbus
12 mm behind the limbus
Ophthalmology
null
2bba5653-ad8f-4640-86d7-f156e4594685
multi
Peutz Jeghers syndrome-all are true EXCEPT:March 2013
Ans. C i.e. Radiotherapy is the treatment of choict.
3
Pigmentation of lips & oral mucosa
Polyposis of jejunum
Radiotherapy is the treatment of choice
May turn malignant
Pathology
null
119e6b74-a3fc-4b75-aa9f-cbe04608d862
multi
A 45 year old male had multiple hypoaesthetic mildly erythematous large plaques with elevated margins on trunk and extremities. His ulnar and lateral popliteal nerves on both sides were enlarged. The most probable diagnosis is –
This patient has:- Multiple lesions Hypoesthetic Bilateral symmetrical nerve thickening These favour lepromatous end of the spectrum. Now question arises, whether it is BL or LL. Point two (Hypoesthetic) differentiates the two:- Sensations IL : Hypoesthetic or  Normoesthetic TT : Anesthetic BT : Hypoesthetic somet...
4
Lepromatous leprosy
Borderline leprosy
Borderline tuberculoid leprosy
Borderline lepromatous leprosy
Dental
null
7cab0044-b837-4414-935e-34daed55b69a
multi
True of poisonous snakes are all, except: Delhi 06
Ans. Belly scales are small
2
Fangs present
Belly scales are small
Small head scales
Grooved teeth
Forensic Medicine
null
00c3e3e4-6345-453f-8d62-7c24df895b53
multi
In Abetaltipoproteinemia result in absence of:
A i.e. Chylomicron, B i.e. LDL, C i.e. VLDLAbetalipoproteinemia: is a rare autosomal recessive disease due to defective synthesis or secretion of apo BQ & leads to absent or low level of chylomicrons, VLDL and LDLQ. [Apo protein B is major component of chylomicron (B-48), VLDL & LDL (B- 100)1
4
Chylomicron
LDL
VLDL
All
Biochemistry
null
6e035364-3354-45c1-9e95-0ff57d8590ae
multi
The secondary attack rate of measles is more than mumps. What is the conclusion?
Ans. c (Measles is more infectious than mumps). (Ref: Park PSM 22nd/pg. 58, 96)SECONDARY ATTACK RATE# It is defined as "the number of exposed persons developing the disease within the range of IP, following exposure to primary case"SAR =Number of exposed persons developing the disease within the range of IP------------...
3
Measles is more dangerous than mumps.
Mumps is more dangerous than measles.
Measles is more infectious than mumps.
Measles is more common than mumps.
Social & Preventive Medicine
Communicable Diseases
a9050e02-a2e1-4825-8ac0-b364fe620ed4
single
Most common primary leading to secondaries in pancreas:
Ans. (a) LungRef: Blumgart 5/e p 930-933* Secondary deposits in Pancreas is mc from Renal cell cancer (But on Postmortem studies- Lung cancer has been the topmost to produce secondary to pancreas)
1
Lung
Breast
Colon
Stomach
Surgery
Pancreas
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single
Most common nerve injury associated with thyroid surgery
.The external branch of the superior laryngeal nerve (EBSLN) is at risk of injury during thyroid operations when dissection of the superior pole and ligation of the superior thyroid vessels (STV) are carried out. From that perspective, EBSLN injury poses a threat to handicap all patients undergoing thyroid operations. ...
4
Right recurrent laryngeal
Left recurrent laryngeal
Right internal laryngeal
External branch of superior laryngeal nerve
Pathology
All India exam
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single
Water is used for hardening in -
Water of crystallization is used in Baralime and silica is used in sodalime
2
Sodalime
Baralime
Both
null
Anaesthesia
null
6839518c-62f0-4a05-8763-ce6b43a40580
multi
In tumour lysis syndrome all of the following are seen EXCEPT:
. Hypercalcemia
2
Hypernatremia
Hypercalcemia
Hyperkalemia
Hyperphosphatemia
Pathology
null
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multi
Which of the following most strongly suggests the diagnosis of primary hyperparathyrodism?
Diagnostic criteria for primary hyperparathyroidism and its surgery Ref - semantischolar.org
2
Serum acid phosphatase above 120IU/L
Serum calcium above 11 mg/dL
Urinary calcium below 100 mg/day
Serum alkaline phosphatase abve 120 lU/L
Medicine
Endocrinology
bddaaea4-3663-496f-acbb-ae11f5da01de
multi
Damage to lower pons, leaving upper pons intact, will result in:
Damage to lower pons will damage the apneustic center. This center was causing the breathing to be slow and deep. Upper pons has pneumotaxic center. It causes the breathing to be rapid and shallow. Since this center is intact (and apneustic is damaged), breathing will become shallow and rapid.
2
Apneusis
Rapid, shallow breathing
Irregular gasping type of breathing
No change in pattern of breathing
Physiology
Respiratory System Pa 3
61773ad6-1bec-4565-952d-31b9ca70080e
multi
Pagets disease increases the risk of
Osteosarcoma Osteosarcomas are bulky tumors that are gritty, gray-white, and often contain areas of hemorrhage and cystic degeneration (Fig. 26-24). The tumors frequently destroy the surrounding coices and produce soft tissue masses. They spread exten- sively in the medullary canal, infiltrating and replacing hemato- p...
2
Osteoma
Osteosarcoma
Fivrosarcoma
All
Anatomy
Musculoskeletal system
7550be07-7af8-42e2-8187-1d7f680c6bcf
multi
Mechanism of action on ondensetron -
Ans. is 'd' i.e., 5HT3 antagonist Ondansetron* It is the prototype of a distinct class of antiemetic drugs developed to control cancer chemotherapy/radiotherapy induced vomiting, and later found to be highly effective in PONV and disease/drug associated vomiting as well.* It blocks the depolarizing action of 5-HT exert...
4
RANK ligand inhibitor
MMDA antagonist
NK 1 receptor antagonist
5 HT3 antagonist
Pharmacology
G.I.T
43181a37-7d03-4e58-8941-e4458592e6c4
single
DOC for Tenia Ungum
C i.e. Griseofulvin
3
Ampthotericin B
Miconazole
Gresiofulvin
Nystatin
Skin
null
bcf04ea2-21fa-4b7e-af25-8038e67ecba1
single
Mechanism of action of statins:
Ref: KDT 6th ed. pg. 614* HMG-CoA Reductase Inhibitors (statins): This class of compound is the most efficacious and best tolerated hypolipidaemic drugs.* MOA: Competitively inhibit conversion of HMG-CoA to mevalonate by the enzyme HMG-CoA reductase.* Drugs (Statins): Lovastatin, Simvastatin, Pravstatin, Atorvastatin, ...
3
Inhibit HMG CoA synthase
Stimulate HMG CoA reductase
Inhibit HMG CoA reductase
Stimulate HMG CoA synthase
Pharmacology
C.V.S
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single
HU units value of bone -
Ans. is 'd' i.e., +1000 SubstanceHU unitsWaterDense cortical boneSoft tissueFatLung tissueAir0+ 1000 (+400 to + 1000)+ 40 to + 80- 60 to -100- 400 to -600- 1000
4
0
40
-100
1000
Radiology
Ultrasonography, CT, and MRI
9584b8ee-ad93-4fca-a417-3e9b64ade107
single
What is histological appearance of vaginal mucosa ?
The vagina is a muscular tube. The lining epithelium is stratified squamous. Underneath the epithelium is a layer of lamina propria, which is rich in elastic fibres, and does not have any glands. Under the lamina propria layer is a layer of smooth muscle, which has an inner circular and outer longitudinal layer. Finall...
1
Stratified squamous
Glandular
Simple squamous
Cuboidal
Anatomy
Abdomen and pelvis
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single
The influence of maternal smoking and LBW incidence is studied. Detailed smoking history is taken at first AN visit and smoking history and bih weight were studied later. The type of study is-
prospective coho studies is one which the outcome has not yet occurred at the time the investigation begins.most prospective studies begin in the present and continue into future. ref:park&;s textbook,ed 22,pg no 73
4
Retrospective coho study
Cross sectinal study
Clinical trial
Prospective coho study
Social & Preventive Medicine
Epidemiology
674d900e-9652-4bf7-a2ce-8fb83201518b
single
The percentage of glutaraldehyde, as a medicament during primary tooth pulpotomy is
null
4
4.00%
3.00%
1.50%
2.00%
Dental
null
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single
Snellen's cha is used to test:
Ans. Vision
1
Vision
Refraction
Presbyopia
Colour blindness
Ophthalmology
null
7db4a9cd-afd2-4c33-9569-3fbd409c41ed
single
Site of b-oxidation is ?
Ans. is 'b' i.e., Mitochondria
2
Cytosol
Mitochondria
Lysosome
Golgi apparatus
Biochemistry
null
7b6c196d-56fc-493d-b667-5500d31befca
single
An enzyme that protects the brain from free radical injury is -
null
3
Myeloperoxidase
MAO
Superoxide dismutase
Hydroxylase
Pathology
null
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single
About H. Influenza all true except aEUR'
Capsular polypeptide protein is responsible for virulence Hemophilus Infl uenzae Hemophilus influenzae is a grain negative rod. The name hemophilus influenzae shows some of its features. Hemophilus means "blood loving" This organism requires blood containing medium.for growth H. influenzae requires 2 erythrocyte factor...
3
Requires factor X and V for growth
Rarely presents as meningitis in children less than 2 months of age
Capsular polypeptide protein is responsible for virulence
M.0 invasive disease of H influenza is meningitis
Microbiology
null
05d2afe9-2d32-4588-abcf-87f7e1289f64
multi
In a case of chest pain with pericarditis and pericardial effussion, pain is referred by?
Phrenic nerveThe pericardium is composed of two layers.The tough external layer, the fibrous pericardium. The parietal layer of serous pericardium is attached to its internal surface. The visceral layer of serous pericardium is fused to the hea.The fibrous and parietal pericardia are supplied by the phrenic nerve (C3-0...
1
Phrenic nerve
Superficial cardiac plexus
Deep cardiac plexus
Vagus nerve
Anatomy
null
159ee683-407c-4cdd-9aea-5e1d38722f5d
single
The root canal instrument most likely to break during use is a
null
2
File
Broach
Reamers
Spreaders
Dental
null
492c26bf-4359-4707-bf59-3c00b669e5f8
single
A 60 yrs old male comes to casualty with acute retention of urine since 12 hrs. On examination there was distended bladder. His wife gives a history of taking some drug by the patient since 2 days as he is suffering from depression. The most likely drug is:
Anticholinergic effects of tricyclic antidepressants (TCAs) are most common. These effects result in dry mouth, constipation, urinary retention, blurred vision, and confusion. They are more common with teiary amine TCAs such as amitriptyline and imipramine than with the secondary amine TCAs desipramine and noriptyline....
2
CPZ
Amitriptyline
Haloperidol
Pimozide
Psychiatry
null
730aaf2d-aa82-485f-98e3-ccd8cc33359d
single
Root value of intercostobrachial nerve is
The intercostobrachial nerve is a lateral cutaneous branch of the second intercostal nerve that supplies sensation to the skin of the Axilla . It leaves the second intercostal space at the midaxillary line and subsequently pierces the serratus anterior muscle to enter the subcutaneous tissues of the axilla. The nerve m...
2
T1
T2
T3
T4
Anatomy
Thorax
d30749ac-d52c-4276-88f1-3b580c251ea7
single
What is the most probable diagnosis in this neonate shown below?
a. Infant of diabetic mother(Ref: Nelson's 20/e p 898-899)Large for date baby with hairy pinna suggests a diagnosis of Infant of diabetic mother.
1
Infant of diabetic mother
Beckwith Wiedemann syndrome
Congenital hypothyroidism
IUCR baby
Pediatrics
New Born Infants
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single
True about boundaries of inguinal canal are all, EXCEPT:
Conjoint tendon is formed by the condensation of fibers of internal oblique and transverse abdominis. It forms the posterior wall of inguinal canal.Boundaries of inguinal canal:Anterior wall of inguinal canalis made up of external oblique aponeurosis with some fibers of internal oblique which attach to lateral pa of in...
1
Conjoint tendon is seen anteriorly
Fascia transversalis forms posterior boundary
Inguinal ligament forms the base
Internal oblique forms the roof
Anatomy
null
235fbf73-53ea-423f-a54f-d8d2e840ecb2
multi
Which of the following is the investigation of choice for assessment of depth of penetration and perirectal node involvement in rectal cancer?
Investigations for rectal carcinoma: For Diagnosis: Best diagnosed by sigmoidoscopy (rigid not flexible) and biopsy of tumour Barium enema For Staging: TRUS (transrectal ultrasonography) CT MRI TRUS (Transrectal Ultrasonography) The depth of the tumour invasion can be accurately determined by TRUS, but it cannot detect...
1
MRI scan
CT scan pelvis
Double contrast barium enema
Transrectal ultrasound
Surgery
null
69dd9296-87d9-42df-a7d9-ad33b598ac36
single
"White plague" is
In 1700s,TB was called "White Plague" due to the Paleness of Patients. Ref: Pg No: 317, IAPSM Textbook of Community Medicine
3
Pneumonic Plague
Bubonic Plague
Tuberculosis
leprosy
Social & Preventive Medicine
Communicable diseases
b8287635-071b-4829-a328-8078442ffc37
single
Upon contact between the sperm head and the zona pellucida, penetration of the sperm into the egg is allowed because of:
Ans. A. The acrosome reactionThe acrosome reaction causes a fusion of the plasma membrane and the acrosomal membrane of the sperm, with subsequent release of proteolytic enzymes that help the sperm enter the ovum. The zona reaction and Pro nuclei formation occur after the sperm has entered the ovum. Sperm enter the per...
1
The acrosome reaction
The zona reaction
The perivitelline space
Pro nuclei formation
Physiology
Sex Hormones
434e0bd1-f348-4935-9d22-fdaa06e85389
multi
QRS complex is due to -
Ans. is "d" i.e., Ventricular depolarization Event of ECGCauseP-waveAtrial depolarizationQRS complexVentricular depolarizationTwaveVentricular repolarizationPR intervalRepresents time taken by impulse to travel from SA node to ventricle (Atrial depolarization and AV conduction)QT intervalDuration of full ventricular co...
4
Ventricular repolarization
Atrial depolarization
Conduction through AV node
Ventricular depolarization
Physiology
Heart: Normal Electrocardiogram
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single
The symptoms of hyperparathyroidism include:
Ans. (d) All of the aboveClinical features of Hypoparathyroidism:* Weakness* Fatigue* Polydipsia, Polyuria, Nocturia,* Bone and Joint Pain* Constipation, Decreased appetite, heart burn* Pruritus* Depression* Memory loss* CapO4 and Ca. Oxalate Renal calculi
4
Constipation and muscle weakness
Anorexia and weight loss
Polydipsia and polyuria
All of the above
Surgery
Pancreas
6da98068-1388-4937-8ced-9da4f6cca578
multi
Anorectal anomalies are commonly associated with:
Ref: Robbins Pathologic Basis of Disease, 8th editionExplanation:Anorectal malformations (ARMs)or Imperforate anusThese are birth defects in which the rectum is malformed.The cause of ARMs is unknownThe genetic basis of these anomalies is very complexAnorectal Malformation in Currarino Syndrome represent the only assoc...
1
Cardiac anomalies
Duodenal atresia
CMS abnormalities
Abdominal wall defects
Surgery
Rectum
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multi
A transection made at the lower end of medulla through the pyramids would cause all/except:
B. i.e. Involuantry movements LMN involves anterior horn cells, anterior spinal nerve root and peripheral nerve.- Involuantry movements & tremors are characteristic features of extrapyramidal disorder- Inocordination (ataxia) is mostly seen in cerebellar lesions but UMN lesions may also present with incordination due t...
2
In coordination
Involuntary movements
Spasticity
Increased tendon reflexes
Anatomy
null
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multi
A 48-year-old woman presents with complaints of moderate weight loss over the past 6 months, heat intolerance, palpitations, and fine tremors in the hands. Physical examination reveals the presence of a diffuse goiter and exophthalmos. Which of the following laboratory findings would be expected in this individual?
The description given above is of an individual with Graves' disease. Hypersecretion of thyroid hormone because of stimulation of the TSH receptor by thyroid-stimulating immunoglobulins results in excessive movement of thyroglobulin from the colloid to the plasma. The presence of exophthalmos is thought to be pa of the...
4
Decreased serum T4
Decreased radioactive iodine uptake
Decreased resin T3 uptake
Increased plasma concentration of thyroglobulin
Medicine
null
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single
Causative agent of malaria -
Malarial parasite infecting human belongs to genus plasmodium. P.vivax, P.falciparum,P.malariae,p.ovale.They are protozoa causing malaria in man.In India P.vivax and P. Falciparum are very common.(refer pgno:54 baveja 3 rd edition)
1
Protozoa
Mosquito
Bacteria
Virus
Microbiology
parasitology
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single
Morbid jealousy is diagnostic of-
Morbid (pathological) jealousy is seen in alcoholism.
3
Cocaine
Cannabis
Alcoholism
Tabacco Intoxication
Forensic Medicine
null
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single
All of the following have a causative association with primary epistaxis in an elderly patient except:
Factors associated with Primary adult Epistaxis: 1. CHRONOBIOLOGY The frequency of admission is greatest in the autumn and winter months.This seasonal variation correlates with fluctuations in environmental temperature and humidity. A chronobiological rhythm is also observed at the circadian level where onset of bleedi...
4
Winter season
NSAIDs
Alcohol Consumption
Hypeension
ENT
Epistaxis
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multi
Calabar swelling is produced by-
Calabar Swelling: Localized angioedema and erythema usually on the extremities, characterized by fugitive, swollen lumps of subcutaneous tissue caused by a parasitic filarial worm (Loa loa) endemic to Central and West Africa. The swollen areas migrate with the worm through the body at a speed of about 1 cm per minute a...
2
Onchocerca volvulus
Loa loa
Brugia malayi
Wuchereria bancrofti
Microbiology
null
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single
Following several days of 12-hour daily rehearsals of the symphony orchestra for a performance of a Wagnerian opera, the 52-year-old male conductor experienced such excruciating pain in the posterior aspect of his right forearm that he could no longer direct the musicians. When the maestro's forearm was palpated 2 cm d...
The Deep radial nerve courses between the two heads of the supinator and is located just medial and distal to the lateral epicondyle. It can be compressed by hyperophy of the supinator causing pain and weakness. The Median nerve passes into the forearm flexor compament. Superficial radial nerve courses down the lateral...
4
Compression of the median nerve by the pronator teres
Compression of the median nerve by the flexor digitorum superficialis
Compression of the superficial radial nerve by the brachioradialis
Compression of the deep radial nerve by the supinator
Anatomy
Nerve Lesions
59c99be2-a96b-4c90-9df1-da874789d53a
single
Which of the following will occur in an exclusively breast fed baby -
Ans. is 'a' i.e., Jaundice o "13% of breast fed infants develop unconjugated hyperlbilirubinemia in the 1st week of life. The breast fed infants have higher, bilirubin levels than formula fed infants." o It is due to inhibitory substances (Pregananediol and free fatty acids) in breast milk that interfere with bilirubin...
1
Jaundice
Scurvy
Tetany
Eczema
Pediatrics
null
3332af92-2328-47c5-a573-d945c7aff8a2
single
In school water fluoridation, amount of F used is:
null
3
0.7-1.2 ppm
1.6-3 ppm
3-4 ppm
12 ppm
Dental
null
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single
The chemotherapy drug fluorouracil undergoes a series of chemical changes in vivo that result in a covalent complex such that it is bound to both thymidylate synthase and methylene-tetrahydrofolate. The inhibition of deoxythymidilate formation and subsequent blockage of cell division is due to
Since rapidly multiplying cancer cells are dependent upon the synthesis of deoxythymidilate (dTMP) from deoxyuridylate (dUMP), a prime target in cancer therapy has been inhibition of dTMP synthesis. The anticancer drug fluorouracil is conveed in vivo to fluorodeoxyuridylate (FdUMP), which is an analogue of dUMP. FdUMP ...
3
Allosteric inhibition
Competitive inhibition
Irreversible inhibition
Noncovalent inhibition
Surgery
null
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multi
In the evaluation of a 26-year-old patient with 4 months of secondary amenorrhea, you order serum prolactin and b-hCG assays. The pregnancy test is positive, and the prolactin comes back at 100 ng/mL (normal <25 ng/mL in this assay). This patient requires
There is a marked increase in levels of serum prolactin during gestation to over 10 times those values found in nonpregnant women. If this woman were not pregnant, the prolactin value could easily explain the amenorrhea and further evaluation of hyperprolactinemia would be necessary. The physiologic significance of inc...
1
Routine obstetric care
Computed tomography (CT) scan of her sella turcica to rule out pituitary adenoma
Repeat measurements of serum prolactin to ensure that values do not increase over 300 ng/mL
Bromocriptine to suppress prolactin
Gynaecology & Obstetrics
Physiology & Histology
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single
Knee with leg x- ray of an adolescent boy is shown. Probable diagnosis:
Chondromyxoid Fibroma Disease of adolescent Knee X-ray Sclerotic lesion around the coex in the tibia. . Small eccentric lytic lesion which lie parallel to the long axis of the bone. * Bone cyst with fracture will show a larger lesion and is mostly unilateral. * Osteitis Fibrosis cystica will present with multiple lesio...
1
Chondromyxoid fibroma
Osteosarcoma
Bone cyst with fracture
Osteitis Fibrosis cystica
Orthopaedics
Ohopedics Oncology
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single
Centrilobular necrosis of liver may be seen with -
Ans. is 'c' i.e., CC14 Hepatocellular necrosis: - o Liver necrosis is a common manifestation of many liver diseases and it can present in various ways, o If severe it can cause liver failure. o In some cases however the necrosis is subclinical, revealed only by elevations of liver enzymes in serum, o Various diseases c...
3
Phosphorus
Arsenic
CCI4
Ethanol
Pathology
Liver
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Most diffusable ion in excitable tissue is -
Points to note Concentration of ions Na+ concentration higher in ECF K+ concentration higher in ICF Cl- concentration higher in ECF K+ leak channels allow K+ to move from ICF to ECF Na+ is prevented from entering the cell. Thus diffusion is highest for K+, then Cl- and least for Na+, when the cell is at rest.
2
Na+
K+
PO4-
Cl-
Physiology
null
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single
which of the following tricyclic antidepressent used for peripheral neuropathy
TCA * MECHANISM This is an antidepressant with three rings. It acts by blocking the transpoers of neurotransmitters resulting in increased neurotransmitters in synapse DRUGS AMITRYPTILLINE IMIPRAMINE CLOMIPRAMINE DESIPRAMINE NORIPTILLINE DOXEPINE * USE AMITRYPTILLINE========PAIN WITH DEPRESSION IMIPRAMINE==========CHIL...
1
amitriptilline
clomipramine
fluoxetine
imipramine
Anatomy
General anatomy
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Which aery does not contribute to Little's area
LITTLE'S AREA (Anterior inferior pa of nasal septum) - Usual site for epistaxis in children. Four Aeries anastomose here and form Kiesselbach's Plexus. Anterior ethmoidal aery(Ophthalmic aery) Sphenopalatine(Maxillary aery) Septal branch of superior labial(Facial aery) Greater palatine aery(Maxillary aery) Ref: Dhingra...
4
Septal branch of facial aery
Anterior ethmoidal aery
Sphenopalantine aery
Posterior ethmoidal aery
ENT
Nose and paranasal sinuses
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Erythrophagia and Mononuclear cell infiltration ulcers are seen in -
Erythrophagocytosis (erythrophagia) is characteristic of typhoid ulcer.
4
Necrotising colitis
Ulcerative colitis
Crohn's disease
Typhoid ulcers
Pathology
null
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single
Velvety appearance of stomach is seen in poisoning with:(1995)
Ans: cRef: Parikh, 6th ed, p. 9.10 and 5th ed, p. 748
3
Abrus precatorius
Barbiturates
Arsenic
lead
Forensic Medicine
Toxicology
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single
All are used for the treatment of Pulmonary hypeension except
Refer kDT 6/e p 297 Vasodilators are used for the treatment of Pulmonary hypeension. Treatments include: endothelin receptor antagonists - such as bosentan, ambrisentan and macitentan phosphodiesterase 5 inhibitors - sildenafil and tadalafil prostaglandins - epoprostenol, iloprost and treprostinil soluble guanylate cyc...
4
Endothelin receptor antagonist
Phosphodiesterase inhibitors
Calcium channel blockers
Beta blockers
Pharmacology
Cardiovascular system
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Which of the following is the national level system that provides annual national as well as state level reliable estimation of feility and moality -
.
4
Civil registration system
Census
Adhoc survey
Sample registration system
Social & Preventive Medicine
Biostatistics
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The classification proposed by the International Lymphoma Study Group for non-Hodgkin's lymphoma is known as:
Answer is B (REAL Classification) In 1994, a group of hematopathologists, oncologists and molecular biologists came together (International Lymphoma Study Group) and introduced a new classification, called the 'Revised European-American Classification of Lymphoid Neoplasms (REAL). WHO has now reviewed and updated the r...
2
Kiel classification
REAL classification
WHO classification
Rappapo classification
Medicine
null
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single
Normal intracranial pressure in a child is:
Normal intracranial pressures : - Newborns : < 5mm of Hg - Infants : 6-15 mm of Hg - Children : 10-15mm of Hg ICP is considered severely elevated, if raised above 40mm of Hg
3
< 5mm of Hg
50-80 mm of Hg
10-15 mm of Hg
20-30 mm of Hg
Pediatrics
Raised intracranial tension
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single
MIC-2 is a marker of? -
Harshmohan textbook of pathology 7th edition In Ewings sarcoma - the cell surface marker by the tumor cells of ES / PNET group is CD99 which is a product of MIC2 gene located on X and Y chromosome. .
1
Ewing sarcoma
Chronic lymphocytic leukemia
Mantle cell lymphoma
All of these
Pathology
General pathology
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Cause of hairy leukoplakia which is characterised by severe discomfort on lateral part of the tongue
(B) EBV # Hairy leukoplakia is a distinctive oral lesion that is seen in immunocompromised patients.> Approximately 80% of patients with hairy leukoplakia have been infected with the human immunodeficiency virus (HIV); the presence of this lesion sometimes calls attention to the existence of the infection.> Hairy leuko...
2
HIV
EBV
Herpes virus
HPV
Medicine
Miscellaneous
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single
Which of the following is an impoant disinfectant on account of effectively destroying gram positive and gram negative bacteria, viruses and even spores at low pH levels -
Ans. is 'c' i.e., Chlorine
3
Phenol
Alcohol
Chlorine
Hexachlorophene
Microbiology
null
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single
Which of the following infection, if occurs in the first trimester, leads to maximum incidence of congenital malformations: March 2010
Ans. A: Rubella T = toxoplasmosis: Caused by protozoan - Toxoplasma gondii - Domestic cat is the definitive host with infections : Ingestion of cysts (meats, garden products), Contact with oocysts in feces - Much higher prevalence of infection in European countries - Acute infection usually asymptomatic 1/3 risk of fet...
1
Rubella
Toxoplasmosis
CMV
All of the above
Microbiology
null
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multi
All are antioxidant except -
Ans. is 'd' i.e., Glutamineo There are two types of antioxidant systems :-Enzymatic antioxidant systemThis includeCatalaseSuperoxide dismutase (SOD)Glutathione peroxidaseNon-enzymatic antioxidant systemThis is further subdivided intoVitamins : Vitamin E, Vitamin A & beta carotene. Vitamin C.Minerals : Selenium, Copper,...
4
Vitamin A
Catalase
Cystein
Glutamine
Biochemistry
Vitamins
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multi
Patient because of positive biopsy findings and negative workup undergoes a radical prostatectomy. The pathology repo reveals Gleason score 9/10 and involvement of several pelvic lymph nodes. Which is the most likely site for prostatic cancer metastasis?
Bone metastasis is a characteristic feature of prostatic cancer. The lesions are typically osteoblastic on x-ray, and the serum acid phosphatase level becomes elevated
4
Liver
Kidney
Lung
Bone
Surgery
Prostate and seminal vesicles
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single
Ahus reaction is what type of hypersensitivity reaction
Ahus reaction Localized area of tissue necrosis resulting from acute immune complex vasculitis, usually elicited in the skin. "SHARP" S- Serum sickness, Schick test, SLE H- HS pneumonitis (Farmers lung), HSP A- Ahus reaction R- Reactive ahritis, RA, Raji assay P - PAN, PSGN
1
Localized immune complex
Ag- Ab reaction
Complement mediated
Ab mediated
Pathology
General pathology
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single
Investigation of choice for dysphagia for solids:
Answer is D (Manometry) Esophageal manometry is the gold standard test for esophageal motility disorders. Esophageal Motility Disorders : Manometry is the test of choice Achalasia Cardia Diffuse Oesophageal Spasm (Discoordinated motility) Nutcracker Oesophagus (Hypercontractile motility) Hypeensive LES (Hypercontractil...
4
Barium swallow
Endoscopy
X-ray chest
C.T. scan
Medicine
null
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The following anticancer drug has high emetogenic potential
PLATINUM COORDINATION COMPLEXES Cisplatin Mech of action:- It is hydrolysed intracellularly to produce a highly reactive moiety which causes cross linking of DNA. The oured site is N7 of guanine residue. Adverse effects:- It is a highly emetic drug. Antiemetics are routinely administered before infusing it. The most im...
4
Chlorambucil
Vincristine
6-Mercaptopurine
Cisplatin
Pharmacology
Chemotherapy
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single
Spironolactone should not be given with
Sprinolanctone is a potassium sparing diurectic It doesn't excrete potassium - increasing potassium levels in the blood ACE IN. also increases potassium levels in the blood Hence the combination is contraindicated Ref: KD Tripathi 8th ed
3
Chlohiazide
Beta blockers
ACE inhibitors
Amlodipine
Pharmacology
Cardiovascular system
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single
A total of 5000 patients of glaucoma are identified and surveyed by patient interviews regarding family history of glaucoma. Such a study design is called-
Case series repo: A case series repo is a descriptive study where in more than one patients having a paicular disease are studied. No cause related analysis or hypothesis testing is involved. Case control study: Backward looking/ retrospective study in which multiple risk factors are studied together. Odd's ratio can b...
1
Case series repo
Case control study
Clinical trial
Coho study
Social & Preventive Medicine
Other Analytical Studies
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multi
Based upon this PA ulnar detion view of the wrist, what is the MOST likely diagnosis?
There is focal periostitis at the radial styloid. The radial styloid itself is normal. This is secondary to adjacent inflammation at the extensor pollicis brevis and abductor pollicis longus tendons (De Quervains tenosynovitis). The periosteal reaction of osteomyelitis is usually associated with abnormal underlying bon...
2
Osteomyelitis
De Quervain tenosynovitis
Hyperophic osteoahropathy
Rheumatoid ahritis
Radiology
Skeletal system
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single
Turbinate that aiculates with ethmoid is:
Middle turbinate and superior turbinate are a pa of the ethmoidal bone where as inferior turbinate is an independant bone which aiculates with the ethmoid bone,completing the medial wall of Nasolacrimal duct. Ref. Scotts Brown 7/e,Vol 2 p 1329.
3
superior
Middle
Inferior
All the above
ENT
Nose and paranasal sinuses
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multi
An enzyme that recognizes a specific (palindromic) sequence and cuts within a DNA molecule is?
ANSWER: (D) Restriction endonucleaseREF: Basic Genetics: Textbook and Activities by Ahmed Abouelmagd, Hussein M. Ageely page 117A palindromic sequence is a nucleic acid sequence {DNA or RNA) that is the same whether read 5' (five-prime) to 3' (three prime) on one strand or 5' to 3' on the complementary strand with whic...
4
Exonuclease
Methylase
Modification enzyme
Restriction endonuclease
Pathology
Genetics
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single
In pontaic fever, which antigen is seen in urine-
Ans. is 'a' i.e., Group specific antigen of Legionella serogroup-1 (LP1) o The examination of urine for legionella antigen by ELISA is a rapid and specific method for identifying L pneumophila,o However, disadvantage of urine antigen test is that it only detects Legionella pneumophila serogroup 1 (LP-1) and negative ur...
1
Group specific antigen of Legionella serogroup- 1 (LP 1)
Group specific antigen of L egionella serogroup- 1. (LP 2)
Group specific antigen of Legionella serogroup- 4 (LP 4)
Group specific antigen of Legionella serogroup- 6 (LP 6)
Microbiology
Bacteria
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single
A patient with Hypeension presents with Hypokalemia. Aldosterone levels and Renin levels are both elevated. The most likely diagnosis is
Answer- A. Renal Aery stenosisThe association of High aldosterone and High Renin levels in a hypeensive patient with hypokalemia suggests a diagnosis ofSecondary Hyperaldosteronism of from Renal Aery Stenosis.
1
Renal Aery stenosis
Primary Hyperaldosteronism {Conn's syndrome}
Addison's disease
Cushing's syndrome
Medicine
null
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multi
Mycosis fungoides: March 2013
Ans. A i.e. Cutaneous T cell lymphoma Mycosis fungoides Mycosis fungoides is also known as: Cutaneous T cell lymphoma, Special features: - MC skin lymphoma, - Pautrier's microabscesses - Presents with diffuse erythroderma
1
Cutaneous T cell lymphoma
Fungal infection
Bacterial infection
Cutaneous B cell lymphoma
Skin
null
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Me Callum patch is seen in the:(1988)
Ans: b
2
Right atrium
Left atrium
Left ventricle
Right ventricle
Pathology
C.V.S
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The main catabolic product/products of purine nuleotides in humans is which one of the following:
Ans. (c) Uric AcidRef: Harper's Biochemistry, 30th edn. pg. 347-357Purines are metabolized by several enzymes:GUANINE* A nuclease frees the nucleotide* A nucleotidase creates guanosine* Purine nucleoside phosphorylase converts guanosine to guanine* Guanase converts guanine to xanthine* Xanthine oxidase (a form of xanth...
3
Ammonia + CO2
Ammonia
Uric Acid
CO2 and Water
Biochemistry
Proteins and Amino Acids
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single
Intraoperative Radiotherapy for treating pancreatic carcinoma mainly uses
Electron Beam is preferred for intraoperative Radiotherapy. The Intraoperative radiotherapy (IO) appears to be an ideal therapeutic strategy for pancreatic cancer, Having the advantage of enabling the delivery of high doses of radiation to areas that are at risk for microscopic disease, saving critical organs and reduc...
3
Alpha Rays
Gamma Rays
Electron Beam
Proton beam
Radiology
Radiotherapy Pa 1
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single
Distally, Gubernaculum attaches to all except:-
Gubernaculum is the fibro muscular band which helps in descent of testes. Proximally, it is attached to:- Lower pole of testis. Peritoneum of saccus vaginalis in front of testis. Mesonephric duct. Distally, it is attached to:- Bottom of scrotum. Superficial perineal pouch. Pubic symphysis above penis. Saphenous opening...
4
Pubic symphysis
Superficial perineal pouch
Anterior superior iliac spine
Inguinal ligament
Anatomy
Pelvis and Perineum 2
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MMR (Measles, mumps, rubella) vaccine is an example of:
Ans: a. Live attenuated.. LIVE ATTENUATEDKILLED WHOLE ORGANISMTOXOID PROTEINSPOLYSACCHARIDEGLYCOCONJUGATERCOMBINANTBCG, Yellow fever, OPV, Measles, Mumps, Rubella,Typhoid, Varicella,Rotavirus, Cholera,Cold-adapted influenza,Rotavirus reassoants.ZostTyphoid, Cholera, Plague,Peussis, Influenza,Typhus, lPV, Rabies, JE,Tic...
1
Live attenuated vaccine
Conjugated vaccine
Polysaccharide vaccine
Killed vaccine
Social & Preventive Medicine
null
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single
Which is the most common aerobic bacteria found in vagina?
Normal vaginal flora is mostly aerobic with an average of six different species of bacteria, most common of which is hydrogen peroxide producing lactobacilli. Other commonly found aerobic bacteria found in the vagina are Diphtheroids, Streptococci, Staphylococcus epidermidis and Gardenella vaginalis. Most prevalent ana...
1
Lactobacilli
Gardnerella
Mobilincus
Clostridium
Gynaecology & Obstetrics
null
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single
A 30 year old male presents with severe pain chest, breathlessness, hypotension and ECG shows ST elevation in V3, V4 V5 and V6 leads. He will be best treated with:
Percutaneous transluminal coronary angioplasty (PCTA or angioplasty) is a procedure that is commonly performed on people with hea disease. This procedure is done to open up the blood vessel to allow the blood to pass through more easily PTCA is a minimally invasive procedure to open up blocked coronary aeries, allowing...
4
Streptokinase
t-PA
Heparin
PTCA
Medicine
C.V.S
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Figure B shows:
null
2
Spinal tap needle
Shortened Spinal tap needle assembled with H file
Side vent needle for irrigation
Needle with file for simultaneous filing and irrigation
Dental
null
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single
Which of the following-is the first sign of sexual maturity in boys?
Ans. (d) Increase in testicular sizePlease refer explanation of question 40
4
Increase in height
Appearance of facial hair
Change in voice
Increase in testicular size
Pediatrics
Assessment of Growth
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Thomsen friedensreich phenomenon is -
Ans. is 'b' i.e., Red cell agglutination by all blood group sera Thomsen-Freidenreich Phenomenono Red cell suspensions contaminated with certain bacteria, e.g. pseudomonas aeruginosa, become aggluiinable by alt blood group sera and even by normal human sera,o This is known as Thomsen Friedenreich phenomenon and is due ...
2
Red cells infection by CMV
Red cell agglutination by all blood group sera
Hemolysis of transfused blood
Due to B antigen
Microbiology
Antigen-antibody reaction
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In mood disorder, rapid cyclers are defined as
(A) 4 or more episodes per year# Rapid cycling:> Most people who meet criteria for bipolar disorder experience a number of episodes, on average 0.4 to 0.7 per year, lasting three to six months.> Rapid cycling, however, is a course specifier that may be applied to any of the above subtypes. It is defined as having four ...
1
4 or more episodes per year
Mania occuring during summer
Mania consistent during lunar year
Depressive episodes during winter
Psychiatry
Miscellaneous
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single
Best marker of SLE?
Ans. (b) Anti-ds DNA antibodies(Ref: Harrison 18th/chapter 319)Anti dsDNA is specific for SLE, only in high titers;But still, anti ds DNA is the best marker for SLE because its prevalence in SLE is 70%;Whereas, Anti Sm antibody, which is specific for SLE, but is seen in only 25% patients with SLE
2
Anti Sm antibodies
Anti-ds DNA antibodies
Anti-Histone antibodies
Anti Ro (SS-A) antibodies
Pathology
Immunity
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single
Enzyme deficiency in Hurler syndrome?
Disease name Abbretion Enzyme Defective GaG(s) affected Symptoms Hurler syndrome MPS I a-l-Iduronidase Dermatan sulfate, Heparan sulfate Mental retardation, coarse facial features, hepatosplenomegaly, cloudy cornea Reference: Harper; 30th edition; Page no:639; Table: 50-8
2
Iduronate sulfatase
a-l-Iduronidase
b-Galactosidase
Galactosamine 6-sulfatase
Biochemistry
Metabolism of carbohydrate
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single
Which of the following is a prodrug ?
All ACE inhibitors are prodrugs except captopril and lisinopril.
2
Lisinopril
Enalapril
Chlorpromazine
Dopamine
Pharmacology
null
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When the sympathetic nervous system is activated:
Ans. C. Norepinephrine is released from axons onto the arteriolar wallNerve fibers, not vascular smooth muscle, release norepinephrine. The norepinephrine from the sympathetic nerves simply diffuses from the axons and binds to specific receptors on smooth muscle cells.
3
Norepinephrine is released by the vascular smooth muscle cells
Acetylcholine is released onto vascular smooth muscle cells
Norepinephrine is released from axons onto the arteriolar wall
The arterioles constrict because nitric oxide production is suppressed
Physiology
Nervous System
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multi
Histological finding in Reye&;s syndrome is
Reyes syndrome characterised by mitochondrial injury and decreased synthesis of mitochondrial enzymes in liver. Which leads to rise in blood ammonia and accumulation of triglycerides within hepatocytes. TEXTBOOK OF PATHOLOGY HARSH MOHAN 6TH EDITION PAGE 602
4
Budding and branching of mitochondria
Swelling of endoplasmic reticulum
Para nuclear micro dense deposits
Glycogen depletion
Pathology
G.I.T
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single
All of the following play a significant role in bone resorption except:
Pro-resorptive factors are hormones and cytokines are:- PTH (Parathyroid hormone) 1,25dihydroxyvitamin D3, IL-1 IL-6 TNF (Tumour necrosis factor) LIF (Leukaemia inhibitory factor) Corticosteroids, which activate osteoblasts and stroma cells to produce RANKL and depress OPG.
4
Parathyroid hormone.
Interleukin1.
Interleukin6.
Interferon-gamma.
Dental
null
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Surgical treatment for asymptomatic uterine myoma is indicated if
Management of myomas: Asymptomatic : observation with regular follow up Size < 12 weeks Uncomplicated pregnancy with fibroid Surgery: Size > 12weeks Cornual fibroid causing infeility Pedunculated cornual fibroid Pregnancy with torsion of pedunculated fibroid Symptomatic myoma: Medical: Hormones to shrink the fibroid _ ...
4
If myoma is pedunculated
Tumour is larger than size of 3months pregnancy
Diagnosis is unceain
All the above
Gynaecology & Obstetrics
PCOD, hirsutism and galactorrhea
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