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ChatCM-RAG

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38917600
Pre-trained language models in medicine: A survey.
2,024
Artificial intelligence in medicine
With the rapid progress in Natural Language Processing (NLP), Pre-trained Language Models (PLM) such as BERT, BioBERT, and ChatGPT have shown great potential in various medical NLP tasks. This paper surveys the cutting-edge achievements in applying PLMs to various medical NLP tasks. Specifically, we first brief PLMS and outline the research of PLMs in medicine. Next, we categorise and discuss the types of tasks in medical NLP, covering text summarisation, question-answering, machine translation, sentiment analysis, named entity recognition, information extraction, medical education, relation extraction, and text mining. For each type of task, we first provide an overview of the basic concepts, the main methodologies, the advantages of applying PLMs, the basic steps of applying PLMs application, the datasets for training and testing, and the metrics for task evaluation. Subsequently, a summary of recent important research findings is presented, analysing their motivations, strengths vs weaknesses, similarities vs differences, and discussing potential limitations. Also, we assess the quality and influence of the research reviewed in this paper by comparing the citation count of the papers reviewed and the reputation and impact of the conferences and journals where they are published. Through these indicators, we further identify the most concerned research topics currently. Finally, we look forward to future research directions, including enhancing models' reliability, explainability, and fairness, to promote the application of PLMs in clinical practice. In addition, this survey also collect some download links of some model codes and the relevant datasets, which are valuable references for researchers applying NLP techniques in medicine and medical professionals seeking to enhance their expertise and healthcare service through AI technology.
Luo X; Deng Z; Yang B; Luo MY
10
37881016
Artificial intelligence and increasing misinformation.
2,024
The British journal of psychiatry : the journal of mental science
With the recent advances in artificial intelligence (AI), patients are increasingly exposed to misleading medical information. Generative AI models, including large language models such as ChatGPT, create and modify text, images, audio and video information based on training data. Commercial use of generative AI is expanding rapidly and the public will routinely receive messages created by generative AI. However, generative AI models may be unreliable, routinely make errors and widely spread misinformation. Misinformation created by generative AI about mental illness may include factual errors, nonsense, fabricated sources and dangerous advice. Psychiatrists need to recognise that patients may receive misinformation online, including about medicine and psychiatry.
Monteith S; Glenn T; Geddes JR; Whybrow PC; Achtyes E; Bauer M
0-1
38366043
The Breakthrough of Large Language Models Release for Medical Applications: 1-Year Timeline and Perspectives.
2,024
Journal of medical systems
Within the domain of Natural Language Processing (NLP), Large Language Models (LLMs) represent sophisticated models engineered to comprehend, generate, and manipulate text resembling human language on an extensive scale. They are transformer-based deep learning architectures, obtained through the scaling of model size, pretraining of corpora, and computational resources. The potential healthcare applications of these models primarily involve chatbots and interaction systems for clinical documentation management, and medical literature summarization (Biomedical NLP). The challenge in this field lies in the research for applications in diagnostic and clinical decision support, as well as patient triage. Therefore, LLMs can be used for multiple tasks within patient care, research, and education. Throughout 2023, there has been an escalation in the release of LLMs, some of which are applicable in the healthcare domain. This remarkable output is largely the effect of the customization of pre-trained models for applications like chatbots, virtual assistants, or any system requiring human-like conversational engagement. As healthcare professionals, we recognize the imperative to stay at the forefront of knowledge. However, keeping abreast of the rapid evolution of this technology is practically unattainable, and, above all, understanding its potential applications and limitations remains a subject of ongoing debate. Consequently, this article aims to provide a succinct overview of the recently released LLMs, emphasizing their potential use in the field of medicine. Perspectives for a more extensive range of safe and effective applications are also discussed. The upcoming evolutionary leap involves the transition from an AI-powered model primarily designed for answering medical questions to a more versatile and practical tool for healthcare providers such as generalist biomedical AI systems for multimodal-based calibrated decision-making processes. On the other hand, the development of more accurate virtual clinical partners could enhance patient engagement, offering personalized support, and improving chronic disease management.
Cascella M; Semeraro F; Montomoli J; Bellini V; Piazza O; Bignami E
10
40172683
Hyper-DREAM, a Multimodal Digital Transformation Hypertension Management Platform Integrating Large Language Model and Digital Phenotyping: Multicenter Development and Initial Validation Study.
2,025
Journal of medical systems
Within the mHealth framework, systematic research that collects and analyzes patient data to establish comprehensive digital health archives for hypertensive patients, and leverages large language models (LLMs) to assist clinicians in health management and Blood Pressure (BP) control remains limited. In this study, our aims to describe the design, development and usability evaluation process of a management platform (Hyper-DREAM) for hypertension. Our multidisciplinary team employed an iterative design approach over the course of a year to develop the Hyper-DREAM platform. This platform's primary functionalities encompass multimodal data collection (personal hypertensive digital phenotype archive), multimodal interventions (BP measurement, medication assistance, behavior modification, and hypertension education) and multimodal interactions (clinician-patient engagement and BP Coach component). In August 2024, the mHealth App Usability Questionnaire (MAUQ) was conducted involving 51 hypertensive patients recruited from three distinct centers. In parallel, six clinicians engaged in management activities and contributed feedback via the Doctor's Software Satisfaction Questionnaire (DSSQ). Concurrently, a real-world comparative experiment was conducted to evaluate the usability of the BP Coach, ChatGPT-4o Mini, ChatGPT-4o and clinicians. The comparative experiment demonstrated that the BP Coach achieved significantly higher scores in utility (mean scores 4.05, SD 0.87) and completeness (mean scores 4.12, SD 0.78) when compared to ChatGPT-4o Mini, ChatGPT-4o, and clinicians. In terms of clarity, the BP Coach was slightly lower than clinicians (mean scores 4.03, SD 0.88). In addition, the BP Coach exhibited lower performance in conciseness (mean scores 3.00, SD 0.96). Clinicians reported a marked improvement in work efficiency (2.67 vs. 4.17, P < .001) and experienced faster and more effective patient interactions (3.0 vs. 4.17, P = .004). Furthermore, the Hyper-DREAM platform significantly decreased work intensity (2.5 vs. 3.5, P = .01) and minimized disruptions to daily routines (2.33 vs. 3.55, P = .004). The Hyper-DREAM platform demonstrated significantly greater overall satisfaction compared to the WeChat-based standard management (3.33 vs. 4.17, P = .01). Additionally, clinicians exhibited a markedly higher willingness to integrate the Hyper-DREAM platform into clinical practice (2.67 vs. 4.17, P < .001). Furthermore, patient management time decreased from 11.5 min (SD 1.87) with Wechat-based standard management to 7.5 min (SD 1.84, P = .01) with Hyper-DREAM. Hypertensive patients reported high satisfaction with the Hyper-DREAM platform, including ease of use (mean scores 1.60, SD 0.69), system information arrangement (mean scores 1.69, SD 0.71), and usefulness (mean scores 1.57, SD 0.58). In conclusion, our study presents Hyper-DREAM, a novel artificial intelligence-driven platform for hypertension management, designed to alleviate clinician workload and exhibiting significant promise for clinical application. The Hyper-DREAM platform is distinguished by its user-friendliness, high satisfaction rates, utility, and effective organization of information. Furthermore, the BP Coach component underscores the potential of LLMs in advancing mHealth approaches to hypertension management.
Wang Y; Zhu T; Zhou T; Wu B; Tan W; Ma K; Yao Z; Wang J; Li S; Qin F; Xu Y; Tan L; Liu J; Wang J
0-1