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Intermediate filament-Types-Type III There are four proteins classed as type III intermediate filament proteins, which may form homo- or heteropolymeric proteins.
Desmin IFs are structural components of the sarcomeres in muscle cells and connect different cell organells like the desmosomes with the cytoskeleton.
Glial ... | milkshake721/2.1M-wiki-STEM |
Intermediate filament-Types-Comparison of the lamins to vertebrate cytoskeletal IFs shows that lamins have an extra 42 residues (six heptads) within coil 1b. The c-terminal tail domain contains a nuclear localization signal (NLS), an Ig-fold-like domain, and in most cases a carboxy-terminal CaaX box that is isoprenylat... | milkshake721/2.1M-wiki-STEM |
Intermediate filament-Types-During mitosis, lamins are phosphorylated by MPF, which drives the disassembly of the lamina and the nuclear envelope.
Type VI Beaded filaments: Filensin, Phakinin.
Nestin (was once proposed for reclassification but due to differences, remains as a type VI IF protein)Vertebrate-only. Related... | milkshake721/2.1M-wiki-STEM |
Intermediate filament-Function-Cell adhesion At the plasma membrane, some keratins or desmin interact with desmosomes (cell-cell adhesion) and hemidesmosomes (cell-matrix adhesion) via adapter proteins.
Associated proteins Filaggrin binds to keratin fibers in epidermal cells. Plectin links vimentin to other vimentin fi... | milkshake721/2.1M-wiki-STEM |
Intermediate filament-Diseases arising from mutations in IF genes-Dilated cardiomyoathy (DCM), mutations in the DES gene Arrhythmogenic cardiomyopathy (ACM), mutations in the DES gene Restrictive cardiomyopathy (RCM), mutations in the DES gene Non-compaction cardiomyopathy, mutations in the DES genes Cardiomyopathy in ... | milkshake721/2.1M-wiki-STEM |
Intermediate filament-In other organisms-IF proteins are universal among animals in the form of a nuclear lamin. The Hydra has an additional "nematocilin" derived from the lamin. Cytoplasmic IFs (type I-IV) are only found in Bilateria; they also arose from a gene duplication event involving "type V" nuclear lamin. In a... | milkshake721/2.1M-wiki-STEM |
Lipid IVA 4-amino-4-deoxy-L-arabinosyltransferase-Lipid IVA 4-amino-4-deoxy-L-arabinosyltransferase-Lipid IVA 4-amino-4-deoxy-L-arabinosyltransferase (EC 2.4.2.43, undecaprenyl phosphate-alpha-L-Ara4N transferase, 4-amino-4-deoxy-L-arabinose lipid A transferase, polymyxin resistance protein PmrK, arnT (gene)) is an enz... | milkshake721/2.1M-wiki-STEM |
Neuro (video game)-Neuro (video game)-Neuro is a cyberpunk first-person shooter video game developed by Revolt Games and published by Russobit-M. It was released on 10 March 2006.The game's plot and world is tech-noir and cyberpunk-themed, as well as dystopian, with inspiration drawn from Blade Runner and Akira, and th... | milkshake721/2.1M-wiki-STEM |
Neuro (video game)-Plot-Neuro is a low-key crime drama with a cyberpunk theme and backdrop that philosophizes on the devolution of humankind: Even though humans have spread themselves out amongst the stars and developed technology to improve and enrich their lives, they are still likely to exploit each other whenever p... | milkshake721/2.1M-wiki-STEM |
Neuro (video game)-History-Prior to release, Neuro had been in development since 2002 and was demonstrated at E3s 2003 and 2004. While intended for worldwide release, it was only released in Russia, the CIS (dubbed into Russian) and Taiwan (dubbed into English). In 2010, an academic, Keith Duffy, found out about Neuro ... | milkshake721/2.1M-wiki-STEM |
ABS methods-ABS methods-ABS methods, where the acronym contains the initials of Jozsef Abaffy, Charles G. Broyden and Emilio Spedicato, have been developed since 1981 to generate a large class of algorithms for the following applications: solution of general linear algebraic systems, determined or underdetermined, full... | milkshake721/2.1M-wiki-STEM |
ABS methods-ABS methods-Research on ABS methods has been the outcome of an international collaboration coordinated by Spedicato of university of Bergamo, Italy. It has involved over forty mathematicians from Hungary, UK, China, Iran and other countries. | milkshake721/2.1M-wiki-STEM |
ABS methods-ABS methods-The central element in such methods is the use of a special matrix transformation due essentially to the Hungarian mathematician Jenő Egerváry, who investigated its main properties in some papers that went unnoticed. For the basic problem of solving a linear system of m equations in n variables... | milkshake721/2.1M-wiki-STEM |
ABS methods-ABS methods-Find a solution of the second equation that is also a solution of the first, i.e. find a solution lying in the intersection of the linear varieties of the solutions of the first two equations considered separately. | milkshake721/2.1M-wiki-STEM |
ABS methods-ABS methods-By iteration of the above approach after m' steps one gets a solution of the last equation that is also a solution of the previous equations, hence of the full system. Moreover, it is possible to detect equations that are either redundant or incompatible.Among the main results obtained so far: u... | milkshake721/2.1M-wiki-STEM |
Binomial regression-Binomial regression-In statistics, binomial regression is a regression analysis technique in which the response (often referred to as Y) has a binomial distribution: it is the number of successes in a series of n independent Bernoulli trials, where each trial has probability of success p . In bino... | milkshake721/2.1M-wiki-STEM |
Binomial regression-Binomial regression-Binomial regression is closely related to binary regression: a binary regression can be considered a binomial regression with n=1 , or a regression on ungrouped binary data, while a binomial regression can be considered a regression on grouped binary data (see comparison). Binom... | milkshake721/2.1M-wiki-STEM |
Binomial regression-Example application-In one published example of an application of binomial regression, the details were as follows. The observed outcome variable was whether or not a fault occurred in an industrial process. There were two explanatory variables: the first was a simple two-case factor representing wh... | milkshake721/2.1M-wiki-STEM |
Binomial regression-Specification of model-The response variable Y is assumed to be binomially distributed conditional on the explanatory variables X. The number of trials n is known, and the probability of success for each trial p is specified as a function θ(X). This implies that the conditional expectation and condi... | milkshake721/2.1M-wiki-STEM |
Binomial regression-Specification of model-Models used in binomial regression can often be extended to multinomial data.
There are many methods of generating the values of μ in systematic ways that allow for interpretation of the model; they are discussed below. | milkshake721/2.1M-wiki-STEM |
Binomial regression-Link functions-There is a requirement that the modelling linking the probabilities μ to the explanatory variables should be of a form which only produces values in the range 0 to 1. Many models can be fitted into the form μ=g(η). | milkshake721/2.1M-wiki-STEM |
Binomial regression-Link functions-Here η is an intermediate variable representing a linear combination, containing the regression parameters, of the explanatory variables. The function g is the cumulative distribution function (cdf) of some probability distribution. Usually this probability distribution has a support ... | milkshake721/2.1M-wiki-STEM |
Binomial regression-Link functions-In the case of logistic regression, the link function is the log of the odds ratio or logistic function. In the case of probit, the link is the cdf of the normal distribution. The linear probability model is not a proper binomial regression specification because predictions need not b... | milkshake721/2.1M-wiki-STEM |
Binomial regression-Comparison with binary regression-Binomial regression is closely connected with binary regression. If the response is a binary variable (two possible outcomes), then these alternatives can be coded as 0 or 1 by considering one of the outcomes as "success" and the other as "failure" and considering t... | milkshake721/2.1M-wiki-STEM |
Binomial regression-Comparison with binary choice models-A binary choice model assumes a latent variable Un, the utility (or net benefit) that person n obtains from taking an action (as opposed to not taking the action). The utility the person obtains from taking the action depends on the characteristics of the person,... | milkshake721/2.1M-wiki-STEM |
Binomial regression-Comparison with binary choice models-The person takes the action, yn = 1, if Un > 0. The unobserved term, εn, is assumed to have a logistic distribution. | milkshake721/2.1M-wiki-STEM |
Binomial regression-Comparison with binary choice models-The specification is written succinctly as: Un = βsn + εn if if Un≤0 ε ∼ logistic, standard normal, etc.Let us write it slightly differently: Un = βsn − en if if Un≤0 e ∼ logistic, standard normal, etc.Here we have made the substitution en = −εn. This changes... | milkshake721/2.1M-wiki-STEM |
Binomial regression-Comparison with binary choice models-Denote the cumulative distribution function (CDF) of e as Fe, and the quantile function (inverse CDF) of e as Fe−1.
Note that Pr Pr Pr Pr Pr (en≤β⋅sn)=Fe(β⋅sn) Since Yn is a Bernoulli trial, where Pr (Yn=1), we have E[Yn]=Fe(β⋅sn) or equivalently Fe−1(E[Yn... | milkshake721/2.1M-wiki-STEM |
Binomial regression-Comparison with binary choice models-Note that the two different formalisms — generalized linear models (GLM's) and discrete choice models — are equivalent in the case of simple binary choice models, but can be extended if differing ways: GLM's can easily handle arbitrarily distributed response vari... | milkshake721/2.1M-wiki-STEM |
Binomial regression-Comparison with binary choice models-On the other hand, because discrete choice models are described as types of generative models, it is conceptually easier to extend them to complicated situations with multiple, possibly correlated, choices for each person, or other variations. | milkshake721/2.1M-wiki-STEM |
Binomial regression-Latent variable interpretation / derivation-A latent variable model involving a binomial observed variable Y can be constructed such that Y is related to the latent variable Y* via if if 0.
The latent variable Y* is then related to a set of regression variables X by the model Y∗=Xβ+ϵ.
This results... | milkshake721/2.1M-wiki-STEM |
Reputation system-Reputation system-Reputation systems are programs or algorithms that allow users to rate each other in online communities in order to build trust through reputation. Some common uses of these systems can be found on E-commerce websites such as eBay, Amazon.com, and Etsy as well as online advice commun... | milkshake721/2.1M-wiki-STEM |
Reputation system-Types-Online Howard Rheingold states that online reputation systems are "computer-based technologies that make it possible to manipulate in new and powerful ways an old and essential human trait". Rheingold says that these systems arose as a result of the need for Internet users to gain trust in the i... | milkshake721/2.1M-wiki-STEM |
Reputation system-Types-Reputation banks The emerging sharing economy increases the importance of trust in peer-to-peer marketplaces and services. Users can build up reputation and trust in individual systems but usually don't have the ability to carry those reputations to other systems. Rachel Botsman and Roo Rogers a... | milkshake721/2.1M-wiki-STEM |
Reputation system-Maintaining effective reputation systems-The main function of reputation systems is to build a sense of trust among users of online communities. As with brick and mortar stores, trust and reputation can be built through customer feedback. Paul Resnick from the Association for Computing Machinery descr... | milkshake721/2.1M-wiki-STEM |
Reputation system-Maintaining effective reputation systems-The final problem related to user feedback is eliciting honest feedback from users. Although there is no concrete method for ensuring the truthfulness of feedback, if a community of honest feedback is established, new users will be more likely to give honest fe... | milkshake721/2.1M-wiki-STEM |
Reputation system-Maintaining effective reputation systems-Standardization attempt The IETF proposed a protocol to exchange reputation data. It was originally aimed at email applications, but it was subsequently developed as a general architecture for a reputation-based service, followed by an email-specific part. Howe... | milkshake721/2.1M-wiki-STEM |
Reputation system-Notable examples of practical applications-Search: web (see PageRank) eCommerce: eBay, Epinions, Bizrate, Trustpilot Social news: Reddit, Digg, Imgur Programming communities: Advogato, freelance marketplaces, Stack Overflow Wikis: Increase contribution quantity and quality Internet Security: TrustedSo... | milkshake721/2.1M-wiki-STEM |
Reputation system-Notable examples of practical applications-Academia: general bibliometric measures, e.g. the h-index of a researcher. | milkshake721/2.1M-wiki-STEM |
Reputation system-Reputation as a resource-High reputation capital often confers benefits upon the holder. For example, a wide range of studies have found a positive correlation between seller rating and selling price on eBay, indicating that high reputation can help users obtain more money for their items. High produc... | milkshake721/2.1M-wiki-STEM |
Reputation system-Reputation as a resource-Abstract reputation can be used as a kind of resource, to be traded away for short-term gains or built up by investing effort. For example, a company with a good reputation may sell lower-quality products for higher profit until their reputation falls, or they may sell higher-... | milkshake721/2.1M-wiki-STEM |
Reputation system-Attacks and defense-Reputation systems are in general vulnerable to attacks, and many types of attacks are possible. As the reputation system tries to generate an accurate assessment based on various factors including but not limited to unpredictable user size and potential adversarial environments, t... | milkshake721/2.1M-wiki-STEM |
Reputation system-Attacks and defense-Attacker model The capability of the attacker is determined by several characteristics, e.g., the location of the attacker related to the system (insider attacker vs. outsider attacker). An insider is an entity who has legitimate access to the system and can participate according t... | milkshake721/2.1M-wiki-STEM |
Reputation system-Attacks and defense-As the outsider attack is much more similar to other attacks in a computer system environment, the insider attack gets more focus in the reputation system. Usually, there are some common assumptions: the attackers are motivated either by selfish or malicious intent and the attacker... | milkshake721/2.1M-wiki-STEM |
Reputation system-Attacks and defense-Self-promoting Attack. The attacker falsely increases their own reputation. A typical example is the so-called Sybil attack where an attacker subverts the reputation system by creating a large number of pseudonymous entities, and using them to gain a disproportionately large influe... | milkshake721/2.1M-wiki-STEM |
Reputation system-Attacks and defense-Whitewashing Attack. The attacker uses some system vulnerability to update their reputation. This attack usually targets the reputation system’s formulation that is used to calculate the reputation result. The whitewashing attack can be combined with other types of attacks to make ... | milkshake721/2.1M-wiki-STEM |
4Pi microscope-4Pi microscope-A 4Pi microscope is a laser scanning fluorescence microscope with an improved axial resolution. With it the typical range of the axial resolution of 500–700 nm can be improved to 100–150 nm, which corresponds to an almost spherical focal spot with 5–7 times less volume than that of standar... | milkshake721/2.1M-wiki-STEM |
4Pi microscope-Working principle-The improvement in resolution is achieved by using two opposing objective lenses, which both are focused to the same geometrical location. Also the difference in optical path length through each of the two objective lenses is carefully aligned to be minimal. By this method, molecules re... | milkshake721/2.1M-wiki-STEM |
4Pi microscope-Working principle-The operation mode of a 4Pi microscope is shown in the figure. The laser light is divided by a beam splitter and directed by mirrors towards the two opposing objective lenses. At the common focal point superposition of both focused light beams occurs. Excited molecules at this position ... | milkshake721/2.1M-wiki-STEM |
4Pi microscope-Working principle-In the ideal case each objective lens can collect light from a solid angle of Ω=2π . With two objective lenses one can collect from every direction (solid angle Ω=4π ). The name of this type of microscopy is derived from the maximal possible solid angle for excitation and detection. P... | milkshake721/2.1M-wiki-STEM |
4Pi microscope-Working principle-In a real 4Pi microscope light cannot be applied or collected from all directions equally, leading to so-called side lobes in the point spread function. Typically (but not always) two-photon excitation microscopy is used in a 4Pi microscope in combination with an emission pinhole to low... | milkshake721/2.1M-wiki-STEM |
4Pi microscope-History-In 1971, Christoph Cremer and Thomas Cremer proposed the creation of a perfect hologram, i.e. one that carries the whole field information of the emission of a point source in all directions, a so-called 4π hologram. However the publication from 1978 had drawn an improper physical conclusion (i.... | milkshake721/2.1M-wiki-STEM |
4Pi microscope-History-Up to now, the best quality in a 4Pi microscope was reached in conjunction with super-resolution techniques like the stimulated emission depletion (STED) principle. Using a 4Pi microscope with appropriate excitation and de-excitation beams, it was possible to create a uniformly 50 nm sized spot, ... | milkshake721/2.1M-wiki-STEM |
Electric dipole moment-Electric dipole moment-The electric dipole moment is a measure of the separation of positive and negative electrical charges within a system, that is, a measure of the system's overall polarity. The SI unit for electric dipole moment is the coulomb-meter (C⋅m). The debye (D) is another unit of me... | milkshake721/2.1M-wiki-STEM |
Electric dipole moment-Elementary definition-Often in physics the dimensions of a massive object can be ignored and can be treated as a pointlike object, i.e. a point particle. Point particles with electric charge are referred to as point charges. Two point charges, one with charge +q and the other one with charge −q s... | milkshake721/2.1M-wiki-STEM |
Electric dipole moment-Elementary definition-A stronger mathematical definition is to use vector algebra, since a quantity with magnitude and direction, like the dipole moment of two point charges, can be expressed in vector form where d is the displacement vector pointing from the negative charge to the positive charg... | milkshake721/2.1M-wiki-STEM |
Electric dipole moment-Energy and torque-An object with an electric dipole moment p is subject to a torque τ when placed in an external electric field E. The torque tends to align the dipole with the field. A dipole aligned parallel to an electric field has lower potential energy than a dipole making some angle with it... | milkshake721/2.1M-wiki-STEM |
Electric dipole moment-Energy and torque-However in a non-uniform electric field a dipole may indeed receive a net force since the force on one end of the dipole no longer balances that on the other end. It can be shown that this net force is generally parallel to the dipole moment. | milkshake721/2.1M-wiki-STEM |
Electric dipole moment-Expression (general case)-More generally, for a continuous distribution of charge confined to a volume V, the corresponding expression for the dipole moment is: where r locates the point of observation and d3r′ denotes an elementary volume in V. For an array of point charges, the charge density b... | milkshake721/2.1M-wiki-STEM |
Electric dipole moment-Expression (general case)-The dipole moment is particularly useful in the context of an overall neutral system of charges, for example a pair of opposite charges, or a neutral conductor in a uniform electric field. For such a system of charges, visualized as an array of paired opposite charges, ... | milkshake721/2.1M-wiki-STEM |
Electric dipole moment-Expression (general case)-This is the vector sum of the individual dipole moments of the neutral charge pairs. (Because of overall charge neutrality, the dipole moment is independent of the observer's position r.) Thus, the value of p is independent of the choice of reference point, provided the ... | milkshake721/2.1M-wiki-STEM |
Electric dipole moment-Expression (general case)-When discussing the dipole moment of a non-neutral system, such as the dipole moment of the proton, a dependence on the choice of reference point arises. In such cases it is conventional to choose the reference point to be the center of mass of the system, not some arbit... | milkshake721/2.1M-wiki-STEM |
Electric dipole moment-Potential and field of an electric dipole-An ideal dipole consists of two opposite charges with infinitesimal separation. We compute the potential and field of such an ideal dipole starting with two opposite charges at separation d > 0, and taking the limit as d → 0.
Two closely spaced opposite c... | milkshake721/2.1M-wiki-STEM |
Electric dipole moment-Potential and field of an electric dipole-where higher order terms in the series are vanishing at large distances, R, compared to d. Here, the electric dipole moment p is, as above: The result for the dipole potential also can be expressed as: which relates the dipole potential to that of a point... | milkshake721/2.1M-wiki-STEM |
Electric dipole moment-Potential and field of an electric dipole-The electric field of the dipole is the negative gradient of the potential, leading to: Thus, although two closely spaced opposite charges are not quite an ideal electric dipole (because their potential at short distances is not that of a dipole), at dist... | milkshake721/2.1M-wiki-STEM |
Electric dipole moment-Potential and field of an electric dipole-As the two charges are brought closer together (d is made smaller), the dipole term in the multipole expansion based on the ratio d/R becomes the only significant term at ever closer distances R, and in the limit of infinitesimal separation the dipole ter... | milkshake721/2.1M-wiki-STEM |
Electric dipole moment-Dipole moment density and polarization density-The dipole moment of an array of charges, determines the degree of polarity of the array, but for a neutral array it is simply a vector property of the array with no information about the array's absolute location. The dipole moment density of the a... | milkshake721/2.1M-wiki-STEM |
Electric dipole moment-Dipole moment density and polarization density-It now is explored just in what way the polarization density P(r) that enters Maxwell's equations is related to the dipole moment p of an overall neutral array of charges, and also to the dipole moment density p(r) (which describes not only the dipol... | milkshake721/2.1M-wiki-STEM |
Electric dipole moment-Dipole moment density and polarization density-A formulation of Maxwell's equations based upon division of charges and currents into "free" and "bound" charges and currents leads to introduction of the D- and P-fields: where P is called the polarization density. In this formulation, the divergenc... | milkshake721/2.1M-wiki-STEM |
Electric dipole moment-Dipole moment density and polarization density-As an aside, in the absence of magnetic effects, Maxwell's equations specify that which implies Applying Helmholtz decomposition: for some scalar potential φ, and: Suppose the charges are divided into free and bound, and the potential is divided into... | milkshake721/2.1M-wiki-STEM |
Electric dipole moment-Dipole moment density and polarization density-Next is discussed how several different dipole moment descriptions of a medium relate to the polarization entering Maxwell's equations. | milkshake721/2.1M-wiki-STEM |
Electric dipole moment-Dipole moment density and polarization density-Medium with charge and dipole densities As described next, a model for polarization moment density p(r) results in a polarization restricted to the same model. For a smoothly varying dipole moment distribution p(r), the corresponding bound charge den... | milkshake721/2.1M-wiki-STEM |
Electric dipole moment-Dipole moment density and polarization density-As a first example relating dipole moment to polarization, consider a medium made up of a continuous charge density ρ(r) and a continuous dipole moment distribution p(r). The potential at a position r is: where ρ(r) is the unpaired charge density, an... | milkshake721/2.1M-wiki-STEM |
Electric dipole moment-Dipole moment density and polarization density-The potential is determined by the total charge, which the above shows consists of: showing that: In short, the dipole moment density p(r) plays the role of the polarization density P for this medium. Notice, p(r) has a non-zero divergence equal to t... | milkshake721/2.1M-wiki-STEM |
Electric dipole moment-Dipole moment density and polarization density-It may be noted that this approach can be extended to include all the multipoles: dipole, quadrupole, etc. Using the relation: the polarization density is found to be: where the added terms are meant to indicate contributions from higher multipoles. ... | milkshake721/2.1M-wiki-STEM |
Electric dipole moment-Dipole moment density and polarization density-Surface charge Above, discussion was deferred for the first term in the expression for the potential due to the dipoles. Integrating the divergence results in a surface charge. The figure at the right provides an intuitive idea of why a surface charg... | milkshake721/2.1M-wiki-STEM |
Electric dipole moment-Dipole moment density and polarization density-This idea is given mathematical form using the potential expression above. Ignoring the free charge, the potential is: Using the divergence theorem, the divergence term transforms into the surface integral: with dA0 an element of surface area of the ... | milkshake721/2.1M-wiki-STEM |
Electric dipole moment-Dipole moment density and polarization density-Then: Whenever χ(r) is used to model a step discontinuity at the boundary between two regions, the step produces a surface charge layer. For example, integrating along a normal to the bounding surface from a point just interior to one surface to anot... | milkshake721/2.1M-wiki-STEM |
Electric dipole moment-Dipole moment density and polarization density-Dielectric sphere in uniform external electric field The above general remarks about surface charge are made more concrete by considering the example of a dielectric sphere in a uniform electric field. The sphere is found to adopt a surface charge re... | milkshake721/2.1M-wiki-STEM |
Electric dipole moment-Dipole moment density and polarization density-A uniform external electric field is supposed to point in the z-direction, and spherical-polar coordinates are introduced so the potential created by this field is: The sphere is assumed to be described by a dielectric constant κ, that is, and inside... | milkshake721/2.1M-wiki-STEM |
Electric dipole moment-Dipole moment density and polarization density-General media If observation is confined to regions sufficiently remote from a system of charges, a multipole expansion of the exact polarization density can be made. By truncating this expansion (for example, retaining only the dipole terms, or only... | milkshake721/2.1M-wiki-STEM |
Electric dipole moment-Dipole moment density and polarization density-At locations inside the charge array, to connect an array of paired charges to an approximation involving only a dipole moment density p(r) requires additional considerations. The simplest approximation is to replace the charge array with a model of ... | milkshake721/2.1M-wiki-STEM |
Electric dipole moment-Dipole moment density and polarization density-A more complex model of the point charge array introduces an effective medium by averaging the microscopic charges; for example, the averaging can arrange that only dipole fields play a role. A related approach is to divide the charges into those nea... | milkshake721/2.1M-wiki-STEM |
Electric dipole moment-Electric dipole moments of fundamental particles-Not to be confused with spin which refers to the magnetic dipole moments of particles, much experimental work is continuing on measuring the electric dipole moments (EDM; or anomalous electric dipole moment) of fundamental and composite particles, ... | milkshake721/2.1M-wiki-STEM |
Electric dipole moment-Dipole moments of molecules-Dipole moments in molecules are responsible for the behavior of a substance in the presence of external electric fields. The dipoles tend to be aligned to the external field which can be constant or time-dependent. This effect forms the basis of a modern experimental t... | milkshake721/2.1M-wiki-STEM |
Electric dipole moment-Dipole moments of molecules-Dipole moments can be found in common molecules such as water and also in biomolecules such as proteins.By means of the total dipole moment of some material one can compute the dielectric constant which is related to the more intuitive concept of conductivity. If MTot... | milkshake721/2.1M-wiki-STEM |
Cilansetron-Cilansetron-Cilansetron is an experimental drug that is a 5-HT3 antagonist under development by Solvay Pharmaceuticals.5-HT3 receptors are responsible for causing many things from nausea to excess bowel movements. In conditions such as irritable bowel syndrome (IBS), the receptors have become faulty or over... | milkshake721/2.1M-wiki-STEM |
Cilansetron-Cilansetron-Studies have shown that the drug can improve quality of life in men and women with diarrhea-predominant IBS. Cilansetron is the first 5-HT antagonist specifically designed for IBS that is effective in men as well as women.In 2005, Solvay received response from the U.S. Food and Drug Administrati... | milkshake721/2.1M-wiki-STEM |
COVID-19 pandemic in Guyana-COVID-19 pandemic in Guyana-The COVID-19 pandemic in Guyana was a part of the worldwide pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The virus was confirmed to have reached Guyana on 11 March 2020. The first case was ... | milkshake721/2.1M-wiki-STEM |
COVID-19 pandemic in Guyana-Background-On 12 January 2020, the World Health Organization (WHO) confirmed that a novel coronavirus was the cause of a respiratory illness in a cluster of people in Wuhan City, Hubei Province, China, which was reported to the WHO on 31 December 2019.The case fatality ratio for COVID-19 has... | milkshake721/2.1M-wiki-STEM |
COVID-19 pandemic in Guyana-Timeline-March On 11 March 2020, the first case of coronavirus was recorded in Guyana from a 52-year-old woman with underlying health conditions, including diabetes and hypertension. The woman died at the Georgetown Public Hospital.On 18 March, the Guyana Civil Aviation Authority closed the ... | milkshake721/2.1M-wiki-STEM |
COVID-19 pandemic in Guyana-Timeline-April On 1 April 2020, a second death was announced. The deceased was a 38-year-old former Emergency Medical Technician. The total number of cases is 12: 10 cases in Region 4, 1 in Region 3 and 1 in Region 6. 52 people have been tested thus far.On 2 April, President David Granger an... | milkshake721/2.1M-wiki-STEM |
COVID-19 pandemic in Guyana-Timeline-The Minister of Health announced that all residents of Guyana would be restricted to their homes/yards. A national curfew would come into effect from 6 PM until 6 AM. The curfew had already been declared on 30 March in Region 10. A limited number of essential services would be opera... | milkshake721/2.1M-wiki-STEM |
COVID-19 pandemic in Guyana-Timeline-The Civil Defence Commission (CDC) started a relief program consisting of food and cleaning essentials to the most vulnerable communities.On 6 April, Guyana had reported 29 cases.On 8 April, it was announced that Colonel John Lewis, who had died on 7 April, had contracted COVID-19. ... | milkshake721/2.1M-wiki-STEM |
COVID-19 pandemic in Guyana-Timeline-All post offices would be closed from that 9 April onward. Arrangements were being made for pensioners to collect pensions.On 9 April, the European Union announced a grant of €8 million (US$8.6 million), which would be implemented by the Caribbean Public Health Agency, for the fight... | milkshake721/2.1M-wiki-STEM |
COVID-19 pandemic in Guyana-Timeline-A 6-year-old girl was rushed to the Linden Hospital Complex with serious medical conditions and had been scheduled to be transferred to Georgetown; however, she died within 90 minutes. She would be tested for COVID-19 because she had a fever and trouble breathing, symptoms of the vi... | milkshake721/2.1M-wiki-STEM |
COVID-19 pandemic in Guyana-Timeline-At least 34 Guyanese had died of COVID-19 in New York City by early April according to the Consulate General of Guyana in New York. Prime Minister Moses Nagamootoo said that 10,000 to 12,000 people were stranded in New York alone, but that at the time no repatriation flights would t... | milkshake721/2.1M-wiki-STEM |
COVID-19 pandemic in Guyana-Timeline-Guyana was set to receive 30,000 masks and ventilators from China.On 15 April, the Ministry of Health announced that of the infected cases, 14 were from the East Coast of Demerara, five from the East Bank of Demerara and 17 within central Georgetown which meant that Region 4 had 86%... | milkshake721/2.1M-wiki-STEM |
COVID-19 pandemic in Guyana-Timeline-A seventh death was recorded at the ICU of Georgetown Public Hospital.On 19 April, PAHO announced 7,000 additional COVID-19 test kits would be sent, adding to the initial 2,000 test kits the country had.On 21 April, Marvin Pearce, a Guyanese political activist and supporter of APNU+... | milkshake721/2.1M-wiki-STEM |
COVID-19 pandemic in Guyana-Timeline-May On 6 May 2020, it was disclosed that the tenth death to COVID-19 was tested after the individual passed away due to complications from the virus. The victim was a 64-year-old man in the Palms Geriatric Home. Twelve staff members and 24 other bedridden persons were quarantined. T... | milkshake721/2.1M-wiki-STEM |
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