id string | task_type string | pipeline string | difficulty string | num_hops int64 | question string | context string | reasoning_chain dict | answer string | choices list | modalities list | modality_data list | evidence list | metadata unknown | path_confidence_score float64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
no_tiss_00025 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is CAMK4 most highly expressed? | CAMK4 GENE_EXPRESSED_IN_TISSUE Brain_Cerebellar_Hemisphere | {
"steps": [
{
"hop": 1,
"source_node_id": "CAMK4",
"source_node_type": "GENE",
"source_node_label": "CAMK4",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.6841797534,
"edge_source_db": "GTEx",
"target_no... | C | [
"A. Muscle_Skeletal",
"B. Pancreas",
"C. Brain_Cerebellar_Hemisphere",
"D. Heart_Left_Ventricle"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "CAMK4",
"source_db": "UniProt",
"payload": {
"accession": "Q16566",
"sequence": "MLKVTVPSCSASSCSSVTASAAPGTASLVPDYWIDGSNRDALSDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEK... | [
{
"source_db": "GTEx",
"source_id": "Brain_Cerebellar_Hemisphere",
"text": "CAMK4 GENE_EXPRESSED_IN_TISSUE Brain_Cerebellar_Hemisphere",
"confidence": 0.6841797534
}
] | {
"gene": "CAMK4",
"top_tissue": "Brain_Cerebellar_Hemisphere",
"top_tpm": 111.937
} | 0.68418 |
no_tiss_00026 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is UBQLN2 most highly expressed? | UBQLN2 GENE_EXPRESSED_IN_TISSUE Brain_Cerebellar_Hemisphere | {
"steps": [
{
"hop": 1,
"source_node_id": "UBQLN2",
"source_node_type": "GENE",
"source_node_label": "UBQLN2",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.6278140921,
"edge_source_db": "GTEx",
"target_... | A | [
"A. Brain_Cerebellar_Hemisphere",
"B. Kidney_Cortex",
"C. Testis",
"D. Pancreas"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "UBQLN2",
"source_db": "UniProt",
"payload": {
"accession": "Q9UHD9",
"sequence": "MAENGESSGPPRPSRGPAAAQGSAAAPAEPKIIKVTVKTPKEKEEFAVPENSSVQQFKEAISKRFKSQTDQLVLIFAGKILKDQDTLIQHGIHDGLTVHLVIKSQNRPQGQSTQPSNAAGTNTTSASTPRSN... | [
{
"source_db": "GTEx",
"source_id": "Brain_Cerebellar_Hemisphere",
"text": "UBQLN2 GENE_EXPRESSED_IN_TISSUE Brain_Cerebellar_Hemisphere",
"confidence": 0.6278140921
}
] | {
"gene": "UBQLN2",
"top_tissue": "Brain_Cerebellar_Hemisphere",
"top_tpm": 75.5094
} | 0.627814 |
no_tiss_00027 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is HAP1 most highly expressed? | HAP1 GENE_EXPRESSED_IN_TISSUE Brain_Hypothalamus | {
"steps": [
{
"hop": 1,
"source_node_id": "HAP1",
"source_node_type": "GENE",
"source_node_label": "HAP1",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.486703547,
"edge_source_db": "GTEx",
"target_node_... | D | [
"A. Cells_Cultured_fibroblasts",
"B. Whole_Blood",
"C. Heart_Left_Ventricle",
"D. Brain_Hypothalamus"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "HAP1",
"source_db": "UniProt",
"payload": {
"accession": "P54257",
"sequence": "MRPKRLGRCCAGSRLGPGDPAALTCAPSPSASPAPEPSAQPQARGTGQRVGSRATSGSQFLSEARTGARPASEAGAKAGARRPSAFSAIQGDVRSMPDNSDAPWTRFVFQGPFGSRATGRGTGKAAGIWKTPAA... | [
{
"source_db": "GTEx",
"source_id": "Brain_Hypothalamus",
"text": "HAP1 GENE_EXPRESSED_IN_TISSUE Brain_Hypothalamus",
"confidence": 0.486703547
}
] | {
"gene": "HAP1",
"top_tissue": "Brain_Hypothalamus",
"top_tpm": 27.8617
} | 0.486704 |
no_tiss_00028 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is ADRA2B most highly expressed? | ADRA2B GENE_EXPRESSED_IN_TISSUE Spleen | {
"steps": [
{
"hop": 1,
"source_node_id": "ADRA2B",
"source_node_type": "GENE",
"source_node_label": "ADRA2B",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.3832217577,
"edge_source_db": "GTEx",
"target_... | A | [
"A. Spleen",
"B. Cells_Cultured_fibroblasts",
"C. Cells_EBV-transformed_lymphocytes",
"D. Whole_Blood"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "ADRA2B",
"source_db": "UniProt",
"payload": {
"accession": "P18089",
"sequence": "MDHQDPYSVQATAAIAAAITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADILVATLIIPFSLANELLGYWYFRRTWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEYNSKRTPRRIKCI... | [
{
"source_db": "GTEx",
"source_id": "Spleen",
"text": "ADRA2B GENE_EXPRESSED_IN_TISSUE Spleen",
"confidence": 0.3832217577
}
] | {
"gene": "ADRA2B",
"top_tissue": "Spleen",
"top_tpm": 13.1199
} | 0.383222 |
no_tiss_00029 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is PFN1 most highly expressed? | PFN1 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "PFN1",
"source_node_type": "GENE",
"source_node_label": "PFN1",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 1,
"edge_source_db": "GTEx",
"target_node_id": "Cell... | A | [
"A. Cells_EBV-transformed_lymphocytes",
"B. Brain_Putamen_basal_ganglia",
"C. Brain_Anterior_cingulate_cortex_BA24",
"D. Brain_Cortex"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "PFN1",
"source_db": "UniProt",
"payload": {
"accession": "P07737",
"sequence": "MAGWNAYIDNLMADGTCQDAAIVGYKDSPSVWAAVPGKTFVNITPAEVGVLVGKDRSSFYVNGLTLGGQKCSVIRDSLLQDGEFSMDLRTKSTGGAPTFNVTVTKTDKTLVLLMGKEGVHGGLINKKCYEMASH... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "PFN1 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 1
}
] | {
"gene": "PFN1",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 1612.44
} | 1 |
no_tiss_00030 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is ATP6V1A most highly expressed? | ATP6V1A GENE_EXPRESSED_IN_TISSUE Brain_Cerebellar_Hemisphere | {
"steps": [
{
"hop": 1,
"source_node_id": "ATP6V1A",
"source_node_type": "GENE",
"source_node_label": "ATP6V1A",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.6824819227,
"edge_source_db": "GTEx",
"targe... | A | [
"A. Brain_Cerebellar_Hemisphere",
"B. Muscle_Skeletal",
"C. Heart_Atrial_Appendage",
"D. Heart_Left_Ventricle"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "ATP6V1A",
"source_db": "UniProt",
"payload": {
"accession": "P38606",
"sequence": "MDFSKLPKILDEDKESTFGYVHGVSGPVVTACDMAGAAMYELVRVGHSELVGEIIRLEGDMATIQVYEETSGVSVGDPVLRTGKPLSVELGPGIMGAIFDGIQRPLSDISSQTQSIYIPRGVNVSALSRDI... | [
{
"source_db": "GTEx",
"source_id": "Brain_Cerebellar_Hemisphere",
"text": "ATP6V1A GENE_EXPRESSED_IN_TISSUE Brain_Cerebellar_Hemisphere",
"confidence": 0.6824819227
}
] | {
"gene": "ATP6V1A",
"top_tissue": "Brain_Cerebellar_Hemisphere",
"top_tpm": 110.62
} | 0.682482 |
no_tiss_00031 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is ACTB most highly expressed? | ACTB GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "ACTB",
"source_node_type": "GENE",
"source_node_label": "ACTB",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 1,
"edge_source_db": "GTEx",
"target_node_id": "Cell... | B | [
"A. Muscle_Skeletal",
"B. Cells_EBV-transformed_lymphocytes",
"C. Pancreas",
"D. Heart_Left_Ventricle"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "ACTB",
"source_db": "UniProt",
"payload": {
"accession": "P60709",
"sequence": "MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYV... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "ACTB GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 1
}
] | {
"gene": "ACTB",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 11629.4
} | 1 |
no_tiss_00032 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is ADM most highly expressed? | ADM GENE_EXPRESSED_IN_TISSUE Cells_Cultured_fibroblasts | {
"steps": [
{
"hop": 1,
"source_node_id": "ADM",
"source_node_type": "GENE",
"source_node_label": "ADM",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.9701543449,
"edge_source_db": "GTEx",
"target_node_i... | D | [
"A. Brain_Cerebellum",
"B. Brain_Cerebellar_Hemisphere",
"C. Brain_Anterior_cingulate_cortex_BA24",
"D. Cells_Cultured_fibroblasts"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "ADM",
"source_db": "UniProt",
"payload": {
"accession": "P35318",
"sequence": "MKLVSVALMYLGSLAFLGADTARLDVASEFRKKWNKWALSRGKRELRMSSSYPTGLADVKAGPAQTLIRPQDMKGASRSPEDSSPDAARIRVKRYRQSMNNFQGLRSFGCRFGTCTVQKLAHQIYQFTDKDKDNV... | [
{
"source_db": "GTEx",
"source_id": "Cells_Cultured_fibroblasts",
"text": "ADM GENE_EXPRESSED_IN_TISSUE Cells_Cultured_fibroblasts",
"confidence": 0.9701543449
}
] | {
"gene": "ADM",
"top_tissue": "Cells_Cultured_fibroblasts",
"top_tpm": 813.487
} | 0.970154 |
no_tiss_00033 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is MLH1 most highly expressed? | MLH1 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "MLH1",
"source_node_type": "GENE",
"source_node_label": "MLH1",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.5648507033,
"edge_source_db": "GTEx",
"target_node... | D | [
"A. Whole_Blood",
"B. Pancreas",
"C. Brain_Putamen_basal_ganglia",
"D. Cells_EBV-transformed_lymphocytes"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "MLH1",
"source_db": "UniProt",
"payload": {
"accession": "P40692",
"sequence": "MSFVAGVIRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAKSTSIQVIVKEGGLKLIQIQDNGTGIRKEDLDIVCERFTTSKLQSFEDLASISTYGFRGEALASISHVAHVTITTKTADGKCAYRASYSDGK... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "MLH1 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 0.5648507033
}
] | {
"gene": "MLH1",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 48.5219
} | 0.564851 |
no_tiss_00034 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is AFDN most highly expressed? | AFDN GENE_EXPRESSED_IN_TISSUE Esophagus_Mucosa | {
"steps": [
{
"hop": 1,
"source_node_id": "AFDN",
"source_node_type": "GENE",
"source_node_label": "AFDN",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.606391148,
"edge_source_db": "GTEx",
"target_node_... | D | [
"A. Brain_Putamen_basal_ganglia",
"B. Whole_Blood",
"C. Brain_Amygdala",
"D. Esophagus_Mucosa"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "AFDN",
"source_db": "UniProt",
"payload": {
"accession": "P55196",
"sequence": "MSAGGRDEERRKLADIIHHWNANRLDLFEISQPTEDLEFHGVMRFYFQDKAAGNFATKCIRVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYEVHVSGERRLDIDEKPLVVQLNWNKDDREGRFVLKNENDA... | [
{
"source_db": "GTEx",
"source_id": "Esophagus_Mucosa",
"text": "AFDN GENE_EXPRESSED_IN_TISSUE Esophagus_Mucosa",
"confidence": 0.606391148
}
] | {
"gene": "AFDN",
"top_tissue": "Esophagus_Mucosa",
"top_tpm": 64.9837
} | 0.606391 |
no_tiss_00035 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is MTOR most highly expressed? | MTOR GENE_EXPRESSED_IN_TISSUE Testis | {
"steps": [
{
"hop": 1,
"source_node_id": "MTOR",
"source_node_type": "GENE",
"source_node_label": "MTOR",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.520739699,
"edge_source_db": "GTEx",
"target_node_... | D | [
"A. Whole_Blood",
"B. Pancreas",
"C. Brain_Amygdala",
"D. Testis"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "MTOR",
"source_db": "UniProt",
"payload": {
"accession": "P42345",
"sequence": "MLGTGPAAATTAATTSSNVSVLQQFASGLKSRNEETRAKAAKELQHYVTMELREMSQEESTRFYDQLNHHIFELVSSSDANERKGGILAIASLIGVEGGNATRIGRFANYLRNLLPSNDPVVMEMASKAIGRLA... | [
{
"source_db": "GTEx",
"source_id": "Testis",
"text": "MTOR GENE_EXPRESSED_IN_TISSUE Testis",
"confidence": 0.520739699
}
] | {
"gene": "MTOR",
"top_tissue": "Testis",
"top_tpm": 35.5128
} | 0.52074 |
no_tiss_00036 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is GRN most highly expressed? | GRN GENE_EXPRESSED_IN_TISSUE Esophagus_Mucosa | {
"steps": [
{
"hop": 1,
"source_node_id": "GRN",
"source_node_type": "GENE",
"source_node_label": "GRN",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.9009217563,
"edge_source_db": "GTEx",
"target_node_i... | D | [
"A. Brain_Hippocampus",
"B. Brain_Amygdala",
"C. Brain_Anterior_cingulate_cortex_BA24",
"D. Esophagus_Mucosa"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "GRN",
"source_db": "UniProt",
"payload": {
"accession": "P28799",
"sequence": "MWTLVSWVALTAGLVAGTRCPDGQFCPVACCLDPGGASYSCCRPLLDKWPTTLSRHLGGPCQVDAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADGRSCFQRSGNNSVGAIQCPDSQFECPD... | [
{
"source_db": "GTEx",
"source_id": "Esophagus_Mucosa",
"text": "GRN GENE_EXPRESSED_IN_TISSUE Esophagus_Mucosa",
"confidence": 0.9009217563
}
] | {
"gene": "GRN",
"top_tissue": "Esophagus_Mucosa",
"top_tpm": 503.843
} | 0.900922 |
no_tiss_00037 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is FAT4 most highly expressed? | FAT4 GENE_EXPRESSED_IN_TISSUE Cells_Cultured_fibroblasts | {
"steps": [
{
"hop": 1,
"source_node_id": "FAT4",
"source_node_type": "GENE",
"source_node_label": "FAT4",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.4505445257,
"edge_source_db": "GTEx",
"target_node... | C | [
"A. Brain_Cerebellar_Hemisphere",
"B. Whole_Blood",
"C. Cells_Cultured_fibroblasts",
"D. Cells_EBV-transformed_lymphocytes"
] | [
"expression",
"protein_sequence"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "FAT4",
"source_db": "UniProt",
"payload": {
"accession": "Q6V0I7",
"sequence": "MDLAPDRATGRPWLPLHTLSVSQLLRVFWLLSLLPGQAWVHGAEPRQVFQVLEEQPPGTLVGTIQTRPGFTYRLSESHALFAINSSTGALYTTSTIDRESLPSDVINLVVLSSAPTYPTEVRVLVRDLNDNAPV... | [
{
"source_db": "GTEx",
"source_id": "Cells_Cultured_fibroblasts",
"text": "FAT4 GENE_EXPRESSED_IN_TISSUE Cells_Cultured_fibroblasts",
"confidence": 0.4505445257
}
] | {
"gene": "FAT4",
"top_tissue": "Cells_Cultured_fibroblasts",
"top_tpm": 21.4817
} | 0.450545 |
no_tiss_00038 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is FLT3 most highly expressed? | FLT3 GENE_EXPRESSED_IN_TISSUE Brain_Cerebellar_Hemisphere | {
"steps": [
{
"hop": 1,
"source_node_id": "FLT3",
"source_node_type": "GENE",
"source_node_label": "FLT3",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.4572315624,
"edge_source_db": "GTEx",
"target_node... | B | [
"A. Cells_Cultured_fibroblasts",
"B. Brain_Cerebellar_Hemisphere",
"C. Muscle_Skeletal",
"D. Kidney_Medulla"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "FLT3",
"source_db": "UniProt",
"payload": {
"accession": "P36888",
"sequence": "MPALARDGGQLPLLVVFSAMIFGTITNQDLPVIKCVLINHKNNDSSVGKSSSYPMVSESPEDLGCALRPQSSGTVYEAAAVEVDVSASITLQVLVDAPGNISCLWVFKHSSLNCQPHFDLQNRGVVSMVILKMT... | [
{
"source_db": "GTEx",
"source_id": "Brain_Cerebellar_Hemisphere",
"text": "FLT3 GENE_EXPRESSED_IN_TISSUE Brain_Cerebellar_Hemisphere",
"confidence": 0.4572315624
}
] | {
"gene": "FLT3",
"top_tissue": "Brain_Cerebellar_Hemisphere",
"top_tpm": 22.5447
} | 0.457232 |
no_tiss_00039 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is CAMK4 most highly expressed? | CAMK4 GENE_EXPRESSED_IN_TISSUE Brain_Cerebellar_Hemisphere | {
"steps": [
{
"hop": 1,
"source_node_id": "CAMK4",
"source_node_type": "GENE",
"source_node_label": "CAMK4",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.6841797534,
"edge_source_db": "GTEx",
"target_no... | B | [
"A. Heart_Left_Ventricle",
"B. Brain_Cerebellar_Hemisphere",
"C. Muscle_Skeletal",
"D. Pancreas"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "CAMK4",
"source_db": "UniProt",
"payload": {
"accession": "Q16566",
"sequence": "MLKVTVPSCSASSCSSVTASAAPGTASLVPDYWIDGSNRDALSDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEK... | [
{
"source_db": "GTEx",
"source_id": "Brain_Cerebellar_Hemisphere",
"text": "CAMK4 GENE_EXPRESSED_IN_TISSUE Brain_Cerebellar_Hemisphere",
"confidence": 0.6841797534
}
] | {
"gene": "CAMK4",
"top_tissue": "Brain_Cerebellar_Hemisphere",
"top_tpm": 111.937
} | 0.68418 |
no_tiss_00040 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is BCOR most highly expressed? | BCOR GENE_EXPRESSED_IN_TISSUE Artery_Tibial | {
"steps": [
{
"hop": 1,
"source_node_id": "BCOR",
"source_node_type": "GENE",
"source_node_label": "BCOR",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.4820658063,
"edge_source_db": "GTEx",
"target_node... | B | [
"A. Whole_Blood",
"B. Artery_Tibial",
"C. Brain_Amygdala",
"D. Brain_Anterior_cingulate_cortex_BA24"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "BCOR",
"source_db": "UniProt",
"payload": {
"accession": "Q6W2J9",
"sequence": "MLSATPLYGNVHSWMNSERVRMCGASEDRKILVNDGDASKARLELREENPLNHNVVDASTAHRIDGLAALSMDRTGLIREGLRVPGNIVYSSLCGLGSEKGREAATSTLGGLGFSSERNPEMQFKPNTPETVEA... | [
{
"source_db": "GTEx",
"source_id": "Artery_Tibial",
"text": "BCOR GENE_EXPRESSED_IN_TISSUE Artery_Tibial",
"confidence": 0.4820658063
}
] | {
"gene": "BCOR",
"top_tissue": "Artery_Tibial",
"top_tpm": 26.9516
} | 0.482066 |
no_tiss_00041 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is BRCA1 most highly expressed? | BRCA1 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "BRCA1",
"source_node_type": "GENE",
"source_node_label": "BRCA1",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.4390708163,
"edge_source_db": "GTEx",
"target_no... | C | [
"A. Kidney_Medulla",
"B. Pancreas",
"C. Cells_EBV-transformed_lymphocytes",
"D. Kidney_Cortex"
] | [
"expression",
"intercell_role",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "BRCA1",
"source_db": "UniProt",
"payload": {
"accession": "P38398",
"sequence": "MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKDEVSIIQSMGYRNR... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "BRCA1 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 0.4390708163
}
] | {
"gene": "BRCA1",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 19.7684
} | 0.439071 |
no_tiss_00042 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is DNMT3A most highly expressed? | DNMT3A GENE_EXPRESSED_IN_TISSUE Brain_Cerebellum | {
"steps": [
{
"hop": 1,
"source_node_id": "DNMT3A",
"source_node_type": "GENE",
"source_node_label": "DNMT3A",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.4467203186,
"edge_source_db": "GTEx",
"target_... | D | [
"A. Heart_Left_Ventricle",
"B. Kidney_Cortex",
"C. Liver",
"D. Brain_Cerebellum"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "DNMT3A",
"source_db": "UniProt",
"payload": {
"accession": "Q9Y6K1",
"sequence": "MPAMPSSGPGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVESGDTPKDPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEGAAETLPEASRAV... | [
{
"source_db": "GTEx",
"source_id": "Brain_Cerebellum",
"text": "DNMT3A GENE_EXPRESSED_IN_TISSUE Brain_Cerebellum",
"confidence": 0.4467203186
}
] | {
"gene": "DNMT3A",
"top_tissue": "Brain_Cerebellum",
"top_tpm": 20.8955
} | 0.44672 |
no_tiss_00043 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is ERG most highly expressed? | ERG GENE_EXPRESSED_IN_TISSUE Artery_Aorta | {
"steps": [
{
"hop": 1,
"source_node_id": "ERG",
"source_node_type": "GENE",
"source_node_label": "ERG",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.5656888765,
"edge_source_db": "GTEx",
"target_node_i... | A | [
"A. Artery_Aorta",
"B. Cells_Cultured_fibroblasts",
"C. Cells_EBV-transformed_lymphocytes",
"D. Whole_Blood"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "ERG",
"source_db": "UniProt",
"payload": {
"accession": "P11308",
"sequence": "MASTIKEALSVVSEDQSLFECAYGTPHLAKTEMTASSSSDYGQTSKMSPRVPQQDWLSQPPARVTIKMECNPSQVNGSRNSPDECSVAKGGKMVGSPDTVGMNYGSYMEEKHMPPPNMTTNERRVIVPADPTLWS... | [
{
"source_db": "GTEx",
"source_id": "Artery_Aorta",
"text": "ERG GENE_EXPRESSED_IN_TISSUE Artery_Aorta",
"confidence": 0.5656888765
}
] | {
"gene": "ERG",
"top_tissue": "Artery_Aorta",
"top_tpm": 48.8095
} | 0.565689 |
no_tiss_00044 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is SFRP4 most highly expressed? | SFRP4 GENE_EXPRESSED_IN_TISSUE Cervix_Endocervix | {
"steps": [
{
"hop": 1,
"source_node_id": "SFRP4",
"source_node_type": "GENE",
"source_node_label": "SFRP4",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.9168322383,
"edge_source_db": "GTEx",
"target_no... | D | [
"A. Whole_Blood",
"B. Cells_EBV-transformed_lymphocytes",
"C. Liver",
"D. Cervix_Endocervix"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "SFRP4",
"source_db": "UniProt",
"payload": {
"accession": "Q6FHJ7",
"sequence": "MFLSILVALCLWLHLALGVRGAPCEAVRIPMCRHMPWNITRMPNHLHHSTQENAILAIEQYEELVDVNCSAVLRFFLCAMYAPICTLEFLHDPIKPCKSVCQRARDDCEPLMKMYNHSWPESLACDELPVYDR... | [
{
"source_db": "GTEx",
"source_id": "Cervix_Endocervix",
"text": "SFRP4 GENE_EXPRESSED_IN_TISSUE Cervix_Endocervix",
"confidence": 0.9168322383
}
] | {
"gene": "SFRP4",
"top_tissue": "Cervix_Endocervix",
"top_tpm": 562.501
} | 0.916832 |
no_tiss_00045 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is CHEK2 most highly expressed? | CHEK2 GENE_EXPRESSED_IN_TISSUE Nerve_Tibial | {
"steps": [
{
"hop": 1,
"source_node_id": "CHEK2",
"source_node_type": "GENE",
"source_node_label": "CHEK2",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.3977285804,
"edge_source_db": "GTEx",
"target_no... | C | [
"A. Muscle_Skeletal",
"B. Brain_Cerebellum",
"C. Nerve_Tibial",
"D. Brain_Cerebellar_Hemisphere"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "CHEK2",
"source_db": "UniProt",
"payload": {
"accession": "O96017",
"sequence": "MSRESDVEAQQSHGSSACSQPHGSVTQSQGSSSQSQGISSSSTSTMPNSSQSSHSSSGTLSSLETVSTQELYSIPEDQEPEDQEPEEPTPAPWARLWALQDGFANLECVNDNYWFGRDKSCEYCFDEPLLKRT... | [
{
"source_db": "GTEx",
"source_id": "Nerve_Tibial",
"text": "CHEK2 GENE_EXPRESSED_IN_TISSUE Nerve_Tibial",
"confidence": 0.3977285804
}
] | {
"gene": "CHEK2",
"top_tissue": "Nerve_Tibial",
"top_tpm": 14.6084
} | 0.397729 |
no_tiss_00046 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is AFDN most highly expressed? | AFDN GENE_EXPRESSED_IN_TISSUE Esophagus_Mucosa | {
"steps": [
{
"hop": 1,
"source_node_id": "AFDN",
"source_node_type": "GENE",
"source_node_label": "AFDN",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.606391148,
"edge_source_db": "GTEx",
"target_node_... | A | [
"A. Esophagus_Mucosa",
"B. Brain_Amygdala",
"C. Brain_Putamen_basal_ganglia",
"D. Whole_Blood"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "AFDN",
"source_db": "UniProt",
"payload": {
"accession": "P55196",
"sequence": "MSAGGRDEERRKLADIIHHWNANRLDLFEISQPTEDLEFHGVMRFYFQDKAAGNFATKCIRVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYEVHVSGERRLDIDEKPLVVQLNWNKDDREGRFVLKNENDA... | [
{
"source_db": "GTEx",
"source_id": "Esophagus_Mucosa",
"text": "AFDN GENE_EXPRESSED_IN_TISSUE Esophagus_Mucosa",
"confidence": 0.606391148
}
] | {
"gene": "AFDN",
"top_tissue": "Esophagus_Mucosa",
"top_tpm": 64.9837
} | 0.606391 |
no_tiss_00047 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is ABL2 most highly expressed? | ABL2 GENE_EXPRESSED_IN_TISSUE Cells_Cultured_fibroblasts | {
"steps": [
{
"hop": 1,
"source_node_id": "ABL2",
"source_node_type": "GENE",
"source_node_label": "ABL2",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.5045728982,
"edge_source_db": "GTEx",
"target_node... | A | [
"A. Cells_Cultured_fibroblasts",
"B. Heart_Left_Ventricle",
"C. Liver",
"D. Whole_Blood"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "ABL2",
"source_db": "UniProt",
"payload": {
"accession": "P42684",
"sequence": "MGQQVGRVGEAPGLQQPQPRGIRGSSAARPSGRRRDPAGRTTETGFNIFTQHDHFASCVEDGFEGDKTGGSSPEALHRPYGCDVEPQALNEAIRWSSKENLLGATESDPNLFVALYDFVASGDNTLSITKGEKL... | [
{
"source_db": "GTEx",
"source_id": "Cells_Cultured_fibroblasts",
"text": "ABL2 GENE_EXPRESSED_IN_TISSUE Cells_Cultured_fibroblasts",
"confidence": 0.5045728982
}
] | {
"gene": "ABL2",
"top_tissue": "Cells_Cultured_fibroblasts",
"top_tpm": 31.6541
} | 0.504573 |
no_tiss_00048 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is ERBB4 most highly expressed? | ERBB4 GENE_EXPRESSED_IN_TISSUE Brain_Cerebellar_Hemisphere | {
"steps": [
{
"hop": 1,
"source_node_id": "ERBB4",
"source_node_type": "GENE",
"source_node_label": "ERBB4",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.3345999077,
"edge_source_db": "GTEx",
"target_no... | C | [
"A. Whole_Blood",
"B. Cells_EBV-transformed_lymphocytes",
"C. Brain_Cerebellar_Hemisphere",
"D. Cells_Cultured_fibroblasts"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "ERBB4",
"source_db": "UniProt",
"payload": {
"accession": "Q15303",
"sequence": "MKPATGLWVWVSLLVAAGTVQPSDSQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVMGNLEITSIEHNRDLSFLRSVREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIFLNYRKDGNFGLQE... | [
{
"source_db": "GTEx",
"source_id": "Brain_Cerebellar_Hemisphere",
"text": "ERBB4 GENE_EXPRESSED_IN_TISSUE Brain_Cerebellar_Hemisphere",
"confidence": 0.3345999077
}
] | {
"gene": "ERBB4",
"top_tissue": "Brain_Cerebellar_Hemisphere",
"top_tpm": 9.09125
} | 0.3346 |
no_tiss_00049 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is VCP most highly expressed? | VCP GENE_EXPRESSED_IN_TISSUE Cells_Cultured_fibroblasts | {
"steps": [
{
"hop": 1,
"source_node_id": "VCP",
"source_node_type": "GENE",
"source_node_label": "VCP",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.7872212011,
"edge_source_db": "GTEx",
"target_node_i... | A | [
"A. Cells_Cultured_fibroblasts",
"B. Brain_Amygdala",
"C. Brain_Hippocampus",
"D. Brain_Putamen_basal_ganglia"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "VCP",
"source_db": "UniProt",
"payload": {
"accession": "P55072",
"sequence": "MASGADSKGDDLSTAILKQKNRPNRLIVDEAINEDNSVVSLSQPKMDELQLFRGDTVLLKGKKRREAVCIVLSDDTCSDEKIRMNRVVRNNLRVRLGDVISIQPCPDVKYGKRIHVLPIDDTVEGITGNLFEVYL... | [
{
"source_db": "GTEx",
"source_id": "Cells_Cultured_fibroblasts",
"text": "VCP GENE_EXPRESSED_IN_TISSUE Cells_Cultured_fibroblasts",
"confidence": 0.7872212011
}
] | {
"gene": "VCP",
"top_tissue": "Cells_Cultured_fibroblasts",
"top_tpm": 229.147
} | 0.787221 |
no_tiss_00050 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is SFRP4 most highly expressed? | SFRP4 GENE_EXPRESSED_IN_TISSUE Cervix_Endocervix | {
"steps": [
{
"hop": 1,
"source_node_id": "SFRP4",
"source_node_type": "GENE",
"source_node_label": "SFRP4",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.9168322383,
"edge_source_db": "GTEx",
"target_no... | B | [
"A. Liver",
"B. Cervix_Endocervix",
"C. Cells_EBV-transformed_lymphocytes",
"D. Whole_Blood"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "SFRP4",
"source_db": "UniProt",
"payload": {
"accession": "Q6FHJ7",
"sequence": "MFLSILVALCLWLHLALGVRGAPCEAVRIPMCRHMPWNITRMPNHLHHSTQENAILAIEQYEELVDVNCSAVLRFFLCAMYAPICTLEFLHDPIKPCKSVCQRARDDCEPLMKMYNHSWPESLACDELPVYDR... | [
{
"source_db": "GTEx",
"source_id": "Cervix_Endocervix",
"text": "SFRP4 GENE_EXPRESSED_IN_TISSUE Cervix_Endocervix",
"confidence": 0.9168322383
}
] | {
"gene": "SFRP4",
"top_tissue": "Cervix_Endocervix",
"top_tpm": 562.501
} | 0.916832 |
no_tiss_00051 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is CSF3R most highly expressed? | CSF3R GENE_EXPRESSED_IN_TISSUE Whole_Blood | {
"steps": [
{
"hop": 1,
"source_node_id": "CSF3R",
"source_node_type": "GENE",
"source_node_label": "CSF3R",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 1,
"edge_source_db": "GTEx",
"target_node_id": "Wh... | B | [
"A. Pancreas",
"B. Whole_Blood",
"C. Cells_Cultured_fibroblasts",
"D. Cells_EBV-transformed_lymphocytes"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "CSF3R",
"source_db": "UniProt",
"payload": {
"accession": "Q99062",
"sequence": "MARLGNCSLTWAALIILLLPGSLEECGHISVSAPIVHLGDPITASCIIKQNCSHLDPEPQILWRLGAELQPGGRQQRLSDGTQESIITLPHLNHTQAFLSCCLNWGNSLQILDQVELRAGYPPAIPHNLSCLM... | [
{
"source_db": "GTEx",
"source_id": "Whole_Blood",
"text": "CSF3R GENE_EXPRESSED_IN_TISSUE Whole_Blood",
"confidence": 1
}
] | {
"gene": "CSF3R",
"top_tissue": "Whole_Blood",
"top_tpm": 2125.6
} | 1 |
no_tiss_00052 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is KRAS most highly expressed? | KRAS GENE_EXPRESSED_IN_TISSUE Nerve_Tibial | {
"steps": [
{
"hop": 1,
"source_node_id": "KRAS",
"source_node_type": "GENE",
"source_node_label": "KRAS",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.5004468095,
"edge_source_db": "GTEx",
"target_node... | B | [
"A. Heart_Left_Ventricle",
"B. Nerve_Tibial",
"C. Muscle_Skeletal",
"D. Pancreas"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "KRAS",
"source_db": "UniProt",
"payload": {
"accession": "P01116",
"sequence": "MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLA... | [
{
"source_db": "GTEx",
"source_id": "Nerve_Tibial",
"text": "KRAS GENE_EXPRESSED_IN_TISSUE Nerve_Tibial",
"confidence": 0.5004468095
}
] | {
"gene": "KRAS",
"top_tissue": "Nerve_Tibial",
"top_tpm": 30.7364
} | 0.500447 |
no_tiss_00053 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is CDK12 most highly expressed? | CDK12 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "CDK12",
"source_node_type": "GENE",
"source_node_label": "CDK12",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.4983797527,
"edge_source_db": "GTEx",
"target_no... | A | [
"A. Cells_EBV-transformed_lymphocytes",
"B. Brain_Anterior_cingulate_cortex_BA24",
"C. Brain_Putamen_basal_ganglia",
"D. Brain_Amygdala"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "CDK12",
"source_db": "UniProt",
"payload": {
"accession": "Q9NYV4",
"sequence": "MPNSERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLVSKHKRHKSKHSKDMGLVTPEAASLGTVIKPLVEYDDISSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRSRDLLKAKQTEKEKS... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "CDK12 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 0.4983797527
}
] | {
"gene": "CDK12",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 30.2864
} | 0.49838 |
no_tiss_00054 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is ADORA2A most highly expressed? | ADORA2A GENE_EXPRESSED_IN_TISSUE Brain_Nucleus_accumbens_basal_ganglia | {
"steps": [
{
"hop": 1,
"source_node_id": "ADORA2A",
"source_node_type": "GENE",
"source_node_label": "ADORA2A",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.5501494786,
"edge_source_db": "GTEx",
"targe... | C | [
"A. Muscle_Skeletal",
"B. Pancreas",
"C. Brain_Nucleus_accumbens_basal_ganglia",
"D. Cells_Cultured_fibroblasts"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "ADORA2A",
"source_db": "UniProt",
"payload": {
"accession": "P29274",
"sequence": "MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVL... | [
{
"source_db": "GTEx",
"source_id": "Brain_Nucleus_accumbens_basal_ganglia",
"text": "ADORA2A GENE_EXPRESSED_IN_TISSUE Brain_Nucleus_accumbens_basal_ganglia",
"confidence": 0.5501494786
}
] | {
"gene": "ADORA2A",
"top_tissue": "Brain_Nucleus_accumbens_basal_ganglia",
"top_tpm": 43.7391
} | 0.550149 |
no_tiss_00055 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is PTEN most highly expressed? | PTEN GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "PTEN",
"source_node_type": "GENE",
"source_node_label": "PTEN",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.6007133561,
"edge_source_db": "GTEx",
"target_node... | B | [
"A. Heart_Left_Ventricle",
"B. Cells_EBV-transformed_lymphocytes",
"C. Brain_Putamen_basal_ganglia",
"D. Brain_Hippocampus"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "PTEN",
"source_db": "UniProt",
"payload": {
"accession": "P60484",
"sequence": "MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVM... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "PTEN GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 0.6007133561
}
] | {
"gene": "PTEN",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 62.4455
} | 0.600713 |
no_tiss_00056 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is DNAJC6 most highly expressed? | DNAJC6 GENE_EXPRESSED_IN_TISSUE Brain_Cerebellar_Hemisphere | {
"steps": [
{
"hop": 1,
"source_node_id": "DNAJC6",
"source_node_type": "GENE",
"source_node_label": "DNAJC6",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.6360673154,
"edge_source_db": "GTEx",
"target_... | B | [
"A. Muscle_Skeletal",
"B. Brain_Cerebellar_Hemisphere",
"C. Whole_Blood",
"D. Liver"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "DNAJC6",
"source_db": "UniProt",
"payload": {
"accession": "O75061",
"sequence": "MKDSENKGASSPDMEPSYGGGLFDMVKGGAGRLFSNLKDNLKDTLKDTSSRVIQSVTSYTKGDLDFTYVTSRIIVMSFPLDNVDIGFRNQVDDIRSFLDSRHLDHYTVYNLSPKSYRTAKFHSRVSECSWPI... | [
{
"source_db": "GTEx",
"source_id": "Brain_Cerebellar_Hemisphere",
"text": "DNAJC6 GENE_EXPRESSED_IN_TISSUE Brain_Cerebellar_Hemisphere",
"confidence": 0.6360673154
}
] | {
"gene": "DNAJC6",
"top_tissue": "Brain_Cerebellar_Hemisphere",
"top_tpm": 79.9987
} | 0.636067 |
no_tiss_00057 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is MNX1-AS1 most highly expressed? | MNX1-AS1 GENE_EXPRESSED_IN_TISSUE Testis | {
"steps": [
{
"hop": 1,
"source_node_id": "MNX1-AS1",
"source_node_type": "GENE",
"source_node_label": "MNX1-AS1",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.2436954589,
"edge_source_db": "GTEx",
"tar... | B | [
"A. Whole_Blood",
"B. Testis",
"C. Uterus",
"D. Vagina"
] | [
"expression"
] | [
{
"family": "transcriptomic",
"tag": "expression",
"anchor_node_id": "MNX1-AS1",
"source_db": "GTEx",
"payload": {
"gene": "MNX1-AS1",
"tissues": [
"Adipose_Subcutaneous",
"Adipose_Visceral_Omentum",
"Adrenal_Gland",
"Artery_Aorta",
"Artery_Cor... | [
{
"source_db": "GTEx",
"source_id": "Testis",
"text": "MNX1-AS1 GENE_EXPRESSED_IN_TISSUE Testis",
"confidence": 0.2436954589
}
] | {
"gene": "MNX1-AS1",
"top_tissue": "Testis",
"top_tpm": 4.38508
} | 0.243695 |
no_tiss_00058 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is ACKR3 most highly expressed? | ACKR3 GENE_EXPRESSED_IN_TISSUE Artery_Tibial | {
"steps": [
{
"hop": 1,
"source_node_id": "ACKR3",
"source_node_type": "GENE",
"source_node_label": "ACKR3",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.7479222763,
"edge_source_db": "GTEx",
"target_no... | D | [
"A. Adrenal_Gland",
"B. Whole_Blood",
"C. Brain_Cerebellar_Hemisphere",
"D. Artery_Tibial"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "ACKR3",
"source_db": "UniProt",
"payload": {
"accession": "P25106",
"sequence": "MDLHLFDYSEPGNFSDISWPCNSSDCIVVDTVMCPNMPNKSVLLYTLSFIYIFIFVIGMIANSVVVWVNIQAKTTGYDTHCYILNLAIADLWVVLTIPVWVVSLVQHNQWPMGELTCKVTHLIFSINLFGSIF... | [
{
"source_db": "GTEx",
"source_id": "Artery_Tibial",
"text": "ACKR3 GENE_EXPRESSED_IN_TISSUE Artery_Tibial",
"confidence": 0.7479222763
}
] | {
"gene": "ACKR3",
"top_tissue": "Artery_Tibial",
"top_tpm": 174.425
} | 0.747922 |
no_tiss_00059 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is BLM most highly expressed? | BLM GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "BLM",
"source_node_type": "GENE",
"source_node_label": "BLM",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.4412071328,
"edge_source_db": "GTEx",
"target_node_i... | D | [
"A. Pancreas",
"B. Kidney_Cortex",
"C. Liver",
"D. Cells_EBV-transformed_lymphocytes"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "BLM",
"source_db": "UniProt",
"payload": {
"accession": "P54132",
"sequence": "MAAVPQNNLQEQLERHSARTLNNKLSLSKPKFSGFTFKKKTSSDNNVSVTNVSVAKTPVLRNKDVNVTEDFSFSEPLPNTTNQQRVKDFFKNAPAGQETQRGGSKSLLPDFLQTPKEVVCTTQNTPTVKKSRDTA... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "BLM GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 0.4412071328
}
] | {
"gene": "BLM",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 20.0772
} | 0.441207 |
no_tiss_00060 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is PARK7 most highly expressed? | PARK7 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "PARK7",
"source_node_type": "GENE",
"source_node_label": "PARK7",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.8278453032,
"edge_source_db": "GTEx",
"target_no... | C | [
"A. Pancreas",
"B. Whole_Blood",
"C. Cells_EBV-transformed_lymphocytes",
"D. Skin_Not_Sun_Exposed_Suprapubic"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "PARK7",
"source_db": "UniProt",
"payload": {
"accession": "Q99497",
"sequence": "MASKRALVILAKGAEEMETVIPVDVMRRAGIKVTVAGLAGKDPVQCSRDVVICPDASLEDAKKEGPYDVVVLPGGNLGAQNLSESAAVKEILKEQENRKGLIAAICAGPTALLAHEIGFGSKVTTHPLAKDKM... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "PARK7 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 0.8278453032
}
] | {
"gene": "PARK7",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 303.716
} | 0.827845 |
no_tiss_00061 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is FGFR1 most highly expressed? | FGFR1 GENE_EXPRESSED_IN_TISSUE Artery_Aorta | {
"steps": [
{
"hop": 1,
"source_node_id": "FGFR1",
"source_node_type": "GENE",
"source_node_label": "FGFR1",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.7211640465,
"edge_source_db": "GTEx",
"target_no... | A | [
"A. Artery_Aorta",
"B. Cells_EBV-transformed_lymphocytes",
"C. Whole_Blood",
"D. Liver"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "FGFR1",
"source_db": "UniProt",
"payload": {
"accession": "P11362",
"sequence": "MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDD... | [
{
"source_db": "GTEx",
"source_id": "Artery_Aorta",
"text": "FGFR1 GENE_EXPRESSED_IN_TISSUE Artery_Aorta",
"confidence": 0.7211640465
}
] | {
"gene": "FGFR1",
"top_tissue": "Artery_Aorta",
"top_tpm": 144.816
} | 0.721164 |
no_tiss_00062 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is KMT2C most highly expressed? | KMT2C GENE_EXPRESSED_IN_TISSUE Brain_Cerebellum | {
"steps": [
{
"hop": 1,
"source_node_id": "KMT2C",
"source_node_type": "GENE",
"source_node_label": "KMT2C",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.4805797778,
"edge_source_db": "GTEx",
"target_no... | D | [
"A. Kidney_Cortex",
"B. Whole_Blood",
"C. Heart_Left_Ventricle",
"D. Brain_Cerebellum"
] | [
"expression",
"protein_sequence"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "KMT2C",
"source_db": "UniProt",
"payload": {
"accession": "Q8NEZ4",
"sequence": "MSSEEDKSVEQPQPPPPPPEEPGAPAPSPAAADKRPRGRPRKDGASPFQRARKKPRSRGKTAVEDEDSMDGLETTETETIVETEIKEQSAEEDAEAEVDNSKQLIPTLQRSVSEESANSLVSVGVEAKISEQL... | [
{
"source_db": "GTEx",
"source_id": "Brain_Cerebellum",
"text": "KMT2C GENE_EXPRESSED_IN_TISSUE Brain_Cerebellum",
"confidence": 0.4805797778
}
] | {
"gene": "KMT2C",
"top_tissue": "Brain_Cerebellum",
"top_tpm": 26.6661
} | 0.48058 |
no_tiss_00063 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is AFF3 most highly expressed? | AFF3 GENE_EXPRESSED_IN_TISSUE Brain_Cerebellar_Hemisphere | {
"steps": [
{
"hop": 1,
"source_node_id": "AFF3",
"source_node_type": "GENE",
"source_node_label": "AFF3",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.4670033116,
"edge_source_db": "GTEx",
"target_node... | B | [
"A. Pancreas",
"B. Brain_Cerebellar_Hemisphere",
"C. Cells_EBV-transformed_lymphocytes",
"D. Muscle_Skeletal"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "AFF3",
"source_db": "UniProt",
"payload": {
"accession": "P51826",
"sequence": "MDSFDLALLQEWDLESLCVYEPDRNALRRKERERRNQETQQDDGTFNSSYSLFSEPYKTNKGDELSNRIQNTLGNYDEMKDFLTDRSNQSHLVGVPKPGVPQTPVNKIDEHFVADSRAQNQPSSICSTTTSTPA... | [
{
"source_db": "GTEx",
"source_id": "Brain_Cerebellar_Hemisphere",
"text": "AFF3 GENE_EXPRESSED_IN_TISSUE Brain_Cerebellar_Hemisphere",
"confidence": 0.4670033116
}
] | {
"gene": "AFF3",
"top_tissue": "Brain_Cerebellar_Hemisphere",
"top_tpm": 24.1891
} | 0.467003 |
no_tiss_00064 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is C9orf72 most highly expressed? | C9orf72 GENE_EXPRESSED_IN_TISSUE Brain_Cerebellar_Hemisphere | {
"steps": [
{
"hop": 1,
"source_node_id": "C9orf72",
"source_node_type": "GENE",
"source_node_label": "C9orf72",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.5667436612,
"edge_source_db": "GTEx",
"targe... | A | [
"A. Brain_Cerebellar_Hemisphere",
"B. Heart_Left_Ventricle",
"C. Liver",
"D. Kidney_Cortex"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "C9orf72",
"source_db": "UniProt",
"payload": {
"accession": "Q96LT7",
"sequence": "MSTLCPPPSPAVAKTEIALSGKSPLLAATFAYWDNILGPRVRHIWAPKTEQVLLSDGEITFLANHTLNGEILRNAESGAIDVKFFVLSEKGVIIVSLIFDGNWNGDRSTYGLSIILPQTELSFYLPLHRVC... | [
{
"source_db": "GTEx",
"source_id": "Brain_Cerebellar_Hemisphere",
"text": "C9orf72 GENE_EXPRESSED_IN_TISSUE Brain_Cerebellar_Hemisphere",
"confidence": 0.5667436612
}
] | {
"gene": "C9orf72",
"top_tissue": "Brain_Cerebellar_Hemisphere",
"top_tpm": 49.1738
} | 0.566744 |
no_tiss_00065 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is SPOP most highly expressed? | SPOP GENE_EXPRESSED_IN_TISSUE Colon_Sigmoid | {
"steps": [
{
"hop": 1,
"source_node_id": "SPOP",
"source_node_type": "GENE",
"source_node_label": "SPOP",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.6768037195,
"edge_source_db": "GTEx",
"target_node... | D | [
"A. Pancreas",
"B. Whole_Blood",
"C. Heart_Left_Ventricle",
"D. Colon_Sigmoid"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "SPOP",
"source_db": "UniProt",
"payload": {
"accession": "O43791",
"sequence": "MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFK... | [
{
"source_db": "GTEx",
"source_id": "Colon_Sigmoid",
"text": "SPOP GENE_EXPRESSED_IN_TISSUE Colon_Sigmoid",
"confidence": 0.6768037195
}
] | {
"gene": "SPOP",
"top_tissue": "Colon_Sigmoid",
"top_tpm": 106.326
} | 0.676804 |
no_tiss_00066 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is ATP13A2 most highly expressed? | ATP13A2 GENE_EXPRESSED_IN_TISSUE Brain_Cortex | {
"steps": [
{
"hop": 1,
"source_node_id": "ATP13A2",
"source_node_type": "GENE",
"source_node_label": "ATP13A2",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.691191961,
"edge_source_db": "GTEx",
"target... | D | [
"A. Liver",
"B. Heart_Left_Ventricle",
"C. Heart_Atrial_Appendage",
"D. Brain_Cortex"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "ATP13A2",
"source_db": "UniProt",
"payload": {
"accession": "Q9NQ11",
"sequence": "MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGIPLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPSPQSQAEDGRSQ... | [
{
"source_db": "GTEx",
"source_id": "Brain_Cortex",
"text": "ATP13A2 GENE_EXPRESSED_IN_TISSUE Brain_Cortex",
"confidence": 0.691191961
}
] | {
"gene": "ATP13A2",
"top_tissue": "Brain_Cortex",
"top_tpm": 117.543
} | 0.691192 |
no_tiss_00067 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is MTA3 most highly expressed? | MTA3 GENE_EXPRESSED_IN_TISSUE Ovary | {
"steps": [
{
"hop": 1,
"source_node_id": "MTA3",
"source_node_type": "GENE",
"source_node_label": "MTA3",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.4948145767,
"edge_source_db": "GTEx",
"target_node... | A | [
"A. Ovary",
"B. Heart_Left_Ventricle",
"C. Liver",
"D. Whole_Blood"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "MTA3",
"source_db": "UniProt",
"payload": {
"accession": "Q9BTC8",
"sequence": "MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTASGNVEAKVVCFYRRRDISNTLIMLADKHAKEIEEESETTVEADLTDKQKHQLKHRELFLSRQYESLPATHIRGKCSVALLNETESVLSYLDKEDTFFYSL... | [
{
"source_db": "GTEx",
"source_id": "Ovary",
"text": "MTA3 GENE_EXPRESSED_IN_TISSUE Ovary",
"confidence": 0.4948145767
}
] | {
"gene": "MTA3",
"top_tissue": "Ovary",
"top_tpm": 29.5252
} | 0.494815 |
no_tiss_00068 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is ALK most highly expressed? | ALK GENE_EXPRESSED_IN_TISSUE Pituitary | {
"steps": [
{
"hop": 1,
"source_node_id": "ALK",
"source_node_type": "GENE",
"source_node_label": "ALK",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.218719834,
"edge_source_db": "GTEx",
"target_node_id... | C | [
"A. Liver",
"B. Cells_Cultured_fibroblasts",
"C. Pituitary",
"D. Whole_Blood"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "ALK",
"source_db": "UniProt",
"payload": {
"accession": "Q9UM73",
"sequence": "MGAIGLLWLLPLLLSTAAVGSGMGTGQRAGSPAAGPPLQPREPLSYSRLQRKSLAVDFVVPSLFRVYARDLLLPPSSSELKAGRPEARGSLALDCAPLLRLLGPAPGVSWTAGSPAPAEARTLSRVLKGGSVRKL... | [
{
"source_db": "GTEx",
"source_id": "Pituitary",
"text": "ALK GENE_EXPRESSED_IN_TISSUE Pituitary",
"confidence": 0.218719834
}
] | {
"gene": "ALK",
"top_tissue": "Pituitary",
"top_tpm": 3.53163
} | 0.21872 |
no_tiss_00069 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is MLH1 most highly expressed? | MLH1 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "MLH1",
"source_node_type": "GENE",
"source_node_label": "MLH1",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.5648507033,
"edge_source_db": "GTEx",
"target_node... | A | [
"A. Cells_EBV-transformed_lymphocytes",
"B. Pancreas",
"C. Whole_Blood",
"D. Brain_Putamen_basal_ganglia"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "MLH1",
"source_db": "UniProt",
"payload": {
"accession": "P40692",
"sequence": "MSFVAGVIRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAKSTSIQVIVKEGGLKLIQIQDNGTGIRKEDLDIVCERFTTSKLQSFEDLASISTYGFRGEALASISHVAHVTITTKTADGKCAYRASYSDGK... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "MLH1 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 0.5648507033
}
] | {
"gene": "MLH1",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 48.5219
} | 0.564851 |
no_tiss_00070 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is CSF3R most highly expressed? | CSF3R GENE_EXPRESSED_IN_TISSUE Whole_Blood | {
"steps": [
{
"hop": 1,
"source_node_id": "CSF3R",
"source_node_type": "GENE",
"source_node_label": "CSF3R",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 1,
"edge_source_db": "GTEx",
"target_node_id": "Wh... | B | [
"A. Pancreas",
"B. Whole_Blood",
"C. Cells_EBV-transformed_lymphocytes",
"D. Cells_Cultured_fibroblasts"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "CSF3R",
"source_db": "UniProt",
"payload": {
"accession": "Q99062",
"sequence": "MARLGNCSLTWAALIILLLPGSLEECGHISVSAPIVHLGDPITASCIIKQNCSHLDPEPQILWRLGAELQPGGRQQRLSDGTQESIITLPHLNHTQAFLSCCLNWGNSLQILDQVELRAGYPPAIPHNLSCLM... | [
{
"source_db": "GTEx",
"source_id": "Whole_Blood",
"text": "CSF3R GENE_EXPRESSED_IN_TISSUE Whole_Blood",
"confidence": 1
}
] | {
"gene": "CSF3R",
"top_tissue": "Whole_Blood",
"top_tpm": 2125.6
} | 1 |
no_tiss_00071 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is PPP2R1B most highly expressed? | PPP2R1B GENE_EXPRESSED_IN_TISSUE Liver | {
"steps": [
{
"hop": 1,
"source_node_id": "PPP2R1B",
"source_node_type": "GENE",
"source_node_label": "PPP2R1B",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.6105899062,
"edge_source_db": "GTEx",
"targe... | A | [
"A. Liver",
"B. Whole_Blood",
"C. Heart_Left_Ventricle",
"D. Heart_Atrial_Appendage"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "PPP2R1B",
"source_db": "UniProt",
"payload": {
"accession": "P30154",
"sequence": "MAGASELGTGPGAAGGDGDDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIYDEDEVLLALAEQLGNFTGLVGGPDFAHCLLPPLENLATVEETVVRDKAVESLRQISQEH... | [
{
"source_db": "GTEx",
"source_id": "Liver",
"text": "PPP2R1B GENE_EXPRESSED_IN_TISSUE Liver",
"confidence": 0.6105899062
}
] | {
"gene": "PPP2R1B",
"top_tissue": "Liver",
"top_tpm": 66.9258
} | 0.61059 |
no_tiss_00072 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is CASS4 most highly expressed? | CASS4 GENE_EXPRESSED_IN_TISSUE Lung | {
"steps": [
{
"hop": 1,
"source_node_id": "CASS4",
"source_node_type": "GENE",
"source_node_label": "CASS4",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.4044509396,
"edge_source_db": "GTEx",
"target_no... | C | [
"A. Heart_Left_Ventricle",
"B. Muscle_Skeletal",
"C. Lung",
"D. Pancreas"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "CASS4",
"source_db": "UniProt",
"payload": {
"accession": "Q9NQ75",
"sequence": "MKGTGIMDCAPKALLARALYDNCPDCSDELAFSRGDILTILEQHVPESEGWWKCLLHGRQGLAPANRLQILTEVAADRPCPPFLRGLEEAPASSEETYQVPTLPRPPTPGPVYEQMRSWAEGPQPPTAQVYEF... | [
{
"source_db": "GTEx",
"source_id": "Lung",
"text": "CASS4 GENE_EXPRESSED_IN_TISSUE Lung",
"confidence": 0.4044509396
}
] | {
"gene": "CASS4",
"top_tissue": "Lung",
"top_tpm": 15.3504
} | 0.404451 |
no_tiss_00073 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is APC most highly expressed? | APC GENE_EXPRESSED_IN_TISSUE Brain_Frontal_Cortex_BA9 | {
"steps": [
{
"hop": 1,
"source_node_id": "APC",
"source_node_type": "GENE",
"source_node_label": "APC",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.5266154471,
"edge_source_db": "GTEx",
"target_node_i... | B | [
"A. Whole_Blood",
"B. Brain_Frontal_Cortex_BA9",
"C. Pancreas",
"D. Kidney_Cortex"
] | [
"expression",
"protein_sequence"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "APC",
"source_db": "UniProt",
"payload": {
"accession": "P25054",
"sequence": "MAAASYDQLLKQVEALKMENSNLRQELEDNSNHLTKLETEASNMKEVLKQLQGSIEDEAMASSGQIDLLERLKELNLDSSNFPGVKLRSKMSLRSYGSREGSVSSRSGECSPVPMGSFPRRGFVNGSRESTGYLE... | [
{
"source_db": "GTEx",
"source_id": "Brain_Frontal_Cortex_BA9",
"text": "APC GENE_EXPRESSED_IN_TISSUE Brain_Frontal_Cortex_BA9",
"confidence": 0.5266154471
}
] | {
"gene": "APC",
"top_tissue": "Brain_Frontal_Cortex_BA9",
"top_tpm": 37.0255
} | 0.526615 |
no_tiss_00074 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is CDK4 most highly expressed? | CDK4 GENE_EXPRESSED_IN_TISSUE Cells_Cultured_fibroblasts | {
"steps": [
{
"hop": 1,
"source_node_id": "CDK4",
"source_node_type": "GENE",
"source_node_label": "CDK4",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.7303090492,
"edge_source_db": "GTEx",
"target_node... | B | [
"A. Brain_Hippocampus",
"B. Cells_Cultured_fibroblasts",
"C. Brain_Putamen_basal_ganglia",
"D. Whole_Blood"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "CDK4",
"source_db": "UniProt",
"payload": {
"accession": "P11802",
"sequence": "MATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRRLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMRQFLRGLDFLHAN... | [
{
"source_db": "GTEx",
"source_id": "Cells_Cultured_fibroblasts",
"text": "CDK4 GENE_EXPRESSED_IN_TISSUE Cells_Cultured_fibroblasts",
"confidence": 0.7303090492
}
] | {
"gene": "CDK4",
"top_tissue": "Cells_Cultured_fibroblasts",
"top_tpm": 154.326
} | 0.730309 |
no_tiss_00075 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is PSEN1 most highly expressed? | PSEN1 GENE_EXPRESSED_IN_TISSUE Brain_Spinal_cord_cervical_c-1 | {
"steps": [
{
"hop": 1,
"source_node_id": "PSEN1",
"source_node_type": "GENE",
"source_node_label": "PSEN1",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.534851406,
"edge_source_db": "GTEx",
"target_nod... | C | [
"A. Pancreas",
"B. Liver",
"C. Brain_Spinal_cord_cervical_c-1",
"D. Heart_Left_Ventricle"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "PSEN1",
"source_db": "UniProt",
"payload": {
"accession": "P49768",
"sequence": "MTELPAPLSYFQNAQMSEDNHLSNTVRSQNDNRERQEHNDRRSLGHPEPLSNGRPQGNSRQVVEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLIYTPFTEDTETVGQRALHSI... | [
{
"source_db": "GTEx",
"source_id": "Brain_Spinal_cord_cervical_c-1",
"text": "PSEN1 GENE_EXPRESSED_IN_TISSUE Brain_Spinal_cord_cervical_c-1",
"confidence": 0.534851406
}
] | {
"gene": "PSEN1",
"top_tissue": "Brain_Spinal_cord_cervical_c-1",
"top_tpm": 39.2519
} | 0.534851 |
no_tiss_00076 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is FGFR1 most highly expressed? | FGFR1 GENE_EXPRESSED_IN_TISSUE Artery_Aorta | {
"steps": [
{
"hop": 1,
"source_node_id": "FGFR1",
"source_node_type": "GENE",
"source_node_label": "FGFR1",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.7211640465,
"edge_source_db": "GTEx",
"target_no... | D | [
"A. Whole_Blood",
"B. Liver",
"C. Cells_EBV-transformed_lymphocytes",
"D. Artery_Aorta"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "FGFR1",
"source_db": "UniProt",
"payload": {
"accession": "P11362",
"sequence": "MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDD... | [
{
"source_db": "GTEx",
"source_id": "Artery_Aorta",
"text": "FGFR1 GENE_EXPRESSED_IN_TISSUE Artery_Aorta",
"confidence": 0.7211640465
}
] | {
"gene": "FGFR1",
"top_tissue": "Artery_Aorta",
"top_tpm": 144.816
} | 0.721164 |
no_tiss_00077 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is PSMA6 most highly expressed? | PSMA6 GENE_EXPRESSED_IN_TISSUE Testis | {
"steps": [
{
"hop": 1,
"source_node_id": "PSMA6",
"source_node_type": "GENE",
"source_node_label": "PSMA6",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.834987975,
"edge_source_db": "GTEx",
"target_nod... | D | [
"A. Brain_Putamen_basal_ganglia",
"B. Brain_Hippocampus",
"C. Pancreas",
"D. Testis"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "PSMA6",
"source_db": "UniProt",
"payload": {
"accession": "P60900",
"sequence": "MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAEMRP... | [
{
"source_db": "GTEx",
"source_id": "Testis",
"text": "PSMA6 GENE_EXPRESSED_IN_TISSUE Testis",
"confidence": 0.834987975
}
] | {
"gene": "PSMA6",
"top_tissue": "Testis",
"top_tpm": 319.13
} | 0.834988 |
no_tiss_00078 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is CD68 most highly expressed? | CD68 GENE_EXPRESSED_IN_TISSUE Spleen | {
"steps": [
{
"hop": 1,
"source_node_id": "CD68",
"source_node_type": "GENE",
"source_node_label": "CD68",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.8437118907,
"edge_source_db": "GTEx",
"target_node... | D | [
"A. Brain_Cortex",
"B. Testis",
"C. Brain_Anterior_cingulate_cortex_BA24",
"D. Spleen"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "CD68",
"source_db": "UniProt",
"payload": {
"accession": "P34810",
"sequence": "MRLAVLFSGALLGLLAAQGTGNDCPHKKSATLLPSFTVTPTVTESTGTTSHRTTKSHKTTTHRTTTTGTTSHGPTTATHNPTTTSHGNVTVHPTSNSTATSQGPSTATHSPATTSHGNATVHPTSNSTATSPGF... | [
{
"source_db": "GTEx",
"source_id": "Spleen",
"text": "CD68 GENE_EXPRESSED_IN_TISSUE Spleen",
"confidence": 0.8437118907
}
] | {
"gene": "CD68",
"top_tissue": "Spleen",
"top_tpm": 339.018
} | 0.843712 |
no_tiss_00079 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is ERG most highly expressed? | ERG GENE_EXPRESSED_IN_TISSUE Artery_Aorta | {
"steps": [
{
"hop": 1,
"source_node_id": "ERG",
"source_node_type": "GENE",
"source_node_label": "ERG",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.5656888765,
"edge_source_db": "GTEx",
"target_node_i... | A | [
"A. Artery_Aorta",
"B. Cells_EBV-transformed_lymphocytes",
"C. Cells_Cultured_fibroblasts",
"D. Whole_Blood"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "ERG",
"source_db": "UniProt",
"payload": {
"accession": "P11308",
"sequence": "MASTIKEALSVVSEDQSLFECAYGTPHLAKTEMTASSSSDYGQTSKMSPRVPQQDWLSQPPARVTIKMECNPSQVNGSRNSPDECSVAKGGKMVGSPDTVGMNYGSYMEEKHMPPPNMTTNERRVIVPADPTLWS... | [
{
"source_db": "GTEx",
"source_id": "Artery_Aorta",
"text": "ERG GENE_EXPRESSED_IN_TISSUE Artery_Aorta",
"confidence": 0.5656888765
}
] | {
"gene": "ERG",
"top_tissue": "Artery_Aorta",
"top_tpm": 48.8095
} | 0.565689 |
no_tiss_00080 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is ABCA7 most highly expressed? | ABCA7 GENE_EXPRESSED_IN_TISSUE Pituitary | {
"steps": [
{
"hop": 1,
"source_node_id": "ABCA7",
"source_node_type": "GENE",
"source_node_label": "ABCA7",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.6584594889,
"edge_source_db": "GTEx",
"target_no... | B | [
"A. Heart_Left_Ventricle",
"B. Pituitary",
"C. Heart_Atrial_Appendage",
"D. Ovary"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "ABCA7",
"source_db": "UniProt",
"payload": {
"accession": "Q8IZY2",
"sequence": "MAFWTQLMLLLWKNFMYRRRQPVQLLVELLWPLFLFFILVAVRHSHPPLEHHECHFPNKPLPSAGTVPWLQGLICNVNNTCFPQLTPGEEPGRLSNFNDSLVSRLLADARTVLGGASAHRTLAGLGKLIATLR... | [
{
"source_db": "GTEx",
"source_id": "Pituitary",
"text": "ABCA7 GENE_EXPRESSED_IN_TISSUE Pituitary",
"confidence": 0.6584594889
}
] | {
"gene": "ABCA7",
"top_tissue": "Pituitary",
"top_tpm": 93.5506
} | 0.658459 |
no_tiss_00081 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is CDK4 most highly expressed? | CDK4 GENE_EXPRESSED_IN_TISSUE Cells_Cultured_fibroblasts | {
"steps": [
{
"hop": 1,
"source_node_id": "CDK4",
"source_node_type": "GENE",
"source_node_label": "CDK4",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.7303090492,
"edge_source_db": "GTEx",
"target_node... | C | [
"A. Whole_Blood",
"B. Brain_Hippocampus",
"C. Cells_Cultured_fibroblasts",
"D. Brain_Putamen_basal_ganglia"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "CDK4",
"source_db": "UniProt",
"payload": {
"accession": "P11802",
"sequence": "MATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRRLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMRQFLRGLDFLHAN... | [
{
"source_db": "GTEx",
"source_id": "Cells_Cultured_fibroblasts",
"text": "CDK4 GENE_EXPRESSED_IN_TISSUE Cells_Cultured_fibroblasts",
"confidence": 0.7303090492
}
] | {
"gene": "CDK4",
"top_tissue": "Cells_Cultured_fibroblasts",
"top_tpm": 154.326
} | 0.730309 |
no_tiss_00082 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is BAX most highly expressed? | BAX GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "BAX",
"source_node_type": "GENE",
"source_node_label": "BAX",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.77659884,
"edge_source_db": "GTEx",
"target_node_id"... | A | [
"A. Cells_EBV-transformed_lymphocytes",
"B. Brain_Putamen_basal_ganglia",
"C. Muscle_Skeletal",
"D. Heart_Left_Ventricle"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "BAX",
"source_db": "UniProt",
"payload": {
"accession": "Q07812",
"sequence": "MDGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKLSECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKLVLKALCTKVPELIRT... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "BAX GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 0.77659884
}
] | {
"gene": "BAX",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 212.862
} | 0.776599 |
no_tiss_00083 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is FOXA1 most highly expressed? | FOXA1 GENE_EXPRESSED_IN_TISSUE Prostate | {
"steps": [
{
"hop": 1,
"source_node_id": "FOXA1",
"source_node_type": "GENE",
"source_node_label": "FOXA1",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.6198521575,
"edge_source_db": "GTEx",
"target_no... | A | [
"A. Prostate",
"B. Heart_Left_Ventricle",
"C. Whole_Blood",
"D. Brain_Cerebellar_Hemisphere"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "FOXA1",
"source_db": "UniProt",
"payload": {
"accession": "P55317",
"sequence": "MLGTVKMEGHETSDWNSYYADTQEAYSSVPVSNMNSGLGSMNSMNTYMTMNTMTTSGNMTPASFNMSYANPGLGAGLSPGAVAGMPGGSAGAMNSMTAAGVTAMGTALSPSGMGAMGAQQAASMNGLGPYAAA... | [
{
"source_db": "GTEx",
"source_id": "Prostate",
"text": "FOXA1 GENE_EXPRESSED_IN_TISSUE Prostate",
"confidence": 0.6198521575
}
] | {
"gene": "FOXA1",
"top_tissue": "Prostate",
"top_tpm": 71.4145
} | 0.619852 |
no_tiss_00084 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is FOLH1 most highly expressed? | FOLH1 GENE_EXPRESSED_IN_TISSUE Brain_Spinal_cord_cervical_c-1 | {
"steps": [
{
"hop": 1,
"source_node_id": "FOLH1",
"source_node_type": "GENE",
"source_node_label": "FOLH1",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.596747858,
"edge_source_db": "GTEx",
"target_nod... | C | [
"A. Cells_Cultured_fibroblasts",
"B. Cells_EBV-transformed_lymphocytes",
"C. Brain_Spinal_cord_cervical_c-1",
"D. Whole_Blood"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "FOLH1",
"source_db": "UniProt",
"payload": {
"accession": "Q04609",
"sequence": "MWNLLHETDSAVATARRPRWLCAGALVLAGGFFLLGFLFGWFIKSSNEATNITPKHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINE... | [
{
"source_db": "GTEx",
"source_id": "Brain_Spinal_cord_cervical_c-1",
"text": "FOLH1 GENE_EXPRESSED_IN_TISSUE Brain_Spinal_cord_cervical_c-1",
"confidence": 0.596747858
}
] | {
"gene": "FOLH1",
"top_tissue": "Brain_Spinal_cord_cervical_c-1",
"top_tpm": 60.7309
} | 0.596748 |
no_tiss_00085 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is ERBB2 most highly expressed? | ERBB2 GENE_EXPRESSED_IN_TISSUE Nerve_Tibial | {
"steps": [
{
"hop": 1,
"source_node_id": "ERBB2",
"source_node_type": "GENE",
"source_node_label": "ERBB2",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.7057996671,
"edge_source_db": "GTEx",
"target_no... | B | [
"A. Cells_EBV-transformed_lymphocytes",
"B. Nerve_Tibial",
"C. Whole_Blood",
"D. Brain_Cerebellar_Hemisphere"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "ERBB2",
"source_db": "UniProt",
"payload": {
"accession": "P04626",
"sequence": "MELAALCRWGLLLALLPPGAASTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQDIQEVQGYVLIAHNQVRQVPLQRLRIVRGTQLFEDNYALAVLDNGDPLNNTTPVTGAS... | [
{
"source_db": "GTEx",
"source_id": "Nerve_Tibial",
"text": "ERBB2 GENE_EXPRESSED_IN_TISSUE Nerve_Tibial",
"confidence": 0.7057996671
}
] | {
"gene": "ERBB2",
"top_tissue": "Nerve_Tibial",
"top_tpm": 130.131
} | 0.7058 |
no_tiss_00086 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is MSH2 most highly expressed? | MSH2 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "MSH2",
"source_node_type": "GENE",
"source_node_label": "MSH2",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.5168538316,
"edge_source_db": "GTEx",
"target_node... | D | [
"A. Pancreas",
"B. Liver",
"C. Whole_Blood",
"D. Cells_EBV-transformed_lymphocytes"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "MSH2",
"source_db": "UniProt",
"payload": {
"accession": "P43246",
"sequence": "MAVQPKETLQLESAAEVGFVRFFQGMPEKPTTTVRLFDRGDFYTAHGEDALLAAREVFKTQGVIKYMGPAGAKNLQSVVLSKMNFESFVKDLLLVRQYRVEVYKNRAGNKASKENDWYLAYKASPGNLSQFEDI... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "MSH2 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 0.5168538316
}
] | {
"gene": "MSH2",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 34.5456
} | 0.516854 |
no_tiss_00087 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is AKAP11 most highly expressed? | AKAP11 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "AKAP11",
"source_node_type": "GENE",
"source_node_label": "AKAP11",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.55130567,
"edge_source_db": "GTEx",
"target_no... | D | [
"A. Liver",
"B. Whole_Blood",
"C. Heart_Left_Ventricle",
"D. Cells_EBV-transformed_lymphocytes"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "AKAP11",
"source_db": "UniProt",
"payload": {
"accession": "Q9UKA4",
"sequence": "MATFRNNHMKTKASVRKSFSEDVFQSVKSLLQSQKELCSVTAEDCLQQDEHANLTEVTFLGFNEETDAAHIQDLAAVSLELPDILNSLHFCSLNENEIICMKNINKPLDISSDPLNQSHPSGMLCVMRVSPT... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "AKAP11 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 0.55130567
}
] | {
"gene": "AKAP11",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 44.0979
} | 0.551306 |
no_tiss_00088 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is FIG4 most highly expressed? | FIG4 GENE_EXPRESSED_IN_TISSUE Artery_Tibial | {
"steps": [
{
"hop": 1,
"source_node_id": "FIG4",
"source_node_type": "GENE",
"source_node_label": "FIG4",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.471815394,
"edge_source_db": "GTEx",
"target_node_... | A | [
"A. Artery_Tibial",
"B. Liver",
"C. Pancreas",
"D. Heart_Left_Ventricle"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "FIG4",
"source_db": "UniProt",
"payload": {
"accession": "Q92562",
"sequence": "MPTAAAPIISSVQKLVLYETRARYFLVGSNNAETKYRVLKIDRTEPKDLVIIDDRHVYTQQEVRELLGRLDLGNRTKMGQKGSSGLFRAVSAFGVVGFVRFLEGYYIVLITKRRKMADIGGHAIYKVEDTNMIY... | [
{
"source_db": "GTEx",
"source_id": "Artery_Tibial",
"text": "FIG4 GENE_EXPRESSED_IN_TISSUE Artery_Tibial",
"confidence": 0.471815394
}
] | {
"gene": "FIG4",
"top_tissue": "Artery_Tibial",
"top_tpm": 25.0406
} | 0.471815 |
no_tiss_00089 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is ANG most highly expressed? | ANG GENE_EXPRESSED_IN_TISSUE Liver | {
"steps": [
{
"hop": 1,
"source_node_id": "ANG",
"source_node_type": "GENE",
"source_node_label": "ANG",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.9538665965,
"edge_source_db": "GTEx",
"target_node_i... | B | [
"A. Brain_Cerebellar_Hemisphere",
"B. Liver",
"C. Brain_Frontal_Cortex_BA9",
"D. Brain_Cortex"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "ANG",
"source_db": "UniProt",
"payload": {
"accession": "P03950",
"sequence": "MVMGLGVLLLVFVLGLGLTPPTLAQDNSRYTHFLTQHYDAKPQGRDDRYCESIMRRRGLTSPCKDINTFIHGNKRSIKAICENKNGNPHRENLRISKSSFQVTTCKLHGGSPWPPCQYRATAGFRNVVVACENGL... | [
{
"source_db": "GTEx",
"source_id": "Liver",
"text": "ANG GENE_EXPRESSED_IN_TISSUE Liver",
"confidence": 0.9538665965
}
] | {
"gene": "ANG",
"top_tissue": "Liver",
"top_tpm": 726.803
} | 0.953867 |
no_tiss_00090 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is FUS most highly expressed? | FUS GENE_EXPRESSED_IN_TISSUE Ovary | {
"steps": [
{
"hop": 1,
"source_node_id": "FUS",
"source_node_type": "GENE",
"source_node_label": "FUS",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.7626349216,
"edge_source_db": "GTEx",
"target_node_i... | A | [
"A. Ovary",
"B. Heart_Left_Ventricle",
"C. Pancreas",
"D. Liver"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "FUS",
"source_db": "UniProt",
"payload": {
"accession": "P35637",
"sequence": "MASNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPS... | [
{
"source_db": "GTEx",
"source_id": "Ovary",
"text": "FUS GENE_EXPRESSED_IN_TISSUE Ovary",
"confidence": 0.7626349216
}
] | {
"gene": "FUS",
"top_tissue": "Ovary",
"top_tpm": 193.194
} | 0.762635 |
no_tiss_00091 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is ATP6V1C1 most highly expressed? | ATP6V1C1 GENE_EXPRESSED_IN_TISSUE Brain_Frontal_Cortex_BA9 | {
"steps": [
{
"hop": 1,
"source_node_id": "ATP6V1C1",
"source_node_type": "GENE",
"source_node_label": "ATP6V1C1",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.6178829732,
"edge_source_db": "GTEx",
"tar... | D | [
"A. Heart_Left_Ventricle",
"B. Pancreas",
"C. Muscle_Skeletal",
"D. Brain_Frontal_Cortex_BA9"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "ATP6V1C1",
"source_db": "UniProt",
"payload": {
"accession": "P21283",
"sequence": "MTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGVVKKVAQYMADVLEDSKDKVQENLLANGVDLVTYITRFQWDMAKYPIKQSLKNISEIIAKGVT... | [
{
"source_db": "GTEx",
"source_id": "Brain_Frontal_Cortex_BA9",
"text": "ATP6V1C1 GENE_EXPRESSED_IN_TISSUE Brain_Frontal_Cortex_BA9",
"confidence": 0.6178829732
}
] | {
"gene": "ATP6V1C1",
"top_tissue": "Brain_Frontal_Cortex_BA9",
"top_tpm": 70.436
} | 0.617883 |
no_tiss_00092 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is ALS2 most highly expressed? | ALS2 GENE_EXPRESSED_IN_TISSUE Brain_Cerebellar_Hemisphere | {
"steps": [
{
"hop": 1,
"source_node_id": "ALS2",
"source_node_type": "GENE",
"source_node_label": "ALS2",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.702103678,
"edge_source_db": "GTEx",
"target_node_... | C | [
"A. Whole_Blood",
"B. Brain_Amygdala",
"C. Brain_Cerebellar_Hemisphere",
"D. Pancreas"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "ALS2",
"source_db": "UniProt",
"payload": {
"accession": "Q96Q42",
"sequence": "MDSKKRSSTEAEGSKERGLVHIWQAGSFPITPERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSFGTLPWRSGPVEICPSSPILENALVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEP... | [
{
"source_db": "GTEx",
"source_id": "Brain_Cerebellar_Hemisphere",
"text": "ALS2 GENE_EXPRESSED_IN_TISSUE Brain_Cerebellar_Hemisphere",
"confidence": 0.702103678
}
] | {
"gene": "ALS2",
"top_tissue": "Brain_Cerebellar_Hemisphere",
"top_tpm": 126.825
} | 0.702104 |
no_tiss_00093 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is MAPT most highly expressed? | MAPT GENE_EXPRESSED_IN_TISSUE Brain_Cerebellum | {
"steps": [
{
"hop": 1,
"source_node_id": "MAPT",
"source_node_type": "GENE",
"source_node_label": "MAPT",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.7833071913,
"edge_source_db": "GTEx",
"target_node... | C | [
"A. Cells_EBV-transformed_lymphocytes",
"B. Liver",
"C. Brain_Cerebellum",
"D. Whole_Blood"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "MAPT",
"source_db": "UniProt",
"payload": {
"accession": "P10636",
"sequence": "MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQE... | [
{
"source_db": "GTEx",
"source_id": "Brain_Cerebellum",
"text": "MAPT GENE_EXPRESSED_IN_TISSUE Brain_Cerebellum",
"confidence": 0.7833071913
}
] | {
"gene": "MAPT",
"top_tissue": "Brain_Cerebellum",
"top_tpm": 223.007
} | 0.783307 |
no_tiss_00094 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is POLE most highly expressed? | POLE GENE_EXPRESSED_IN_TISSUE Brain_Cerebellum | {
"steps": [
{
"hop": 1,
"source_node_id": "POLE",
"source_node_type": "GENE",
"source_node_label": "POLE",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.6303841024,
"edge_source_db": "GTEx",
"target_node... | C | [
"A. Brain_Amygdala",
"B. Brain_Substantia_nigra",
"C. Brain_Cerebellum",
"D. Brain_Putamen_basal_ganglia"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "POLE",
"source_db": "UniProt",
"payload": {
"accession": "Q07864",
"sequence": "MSLRSGGRRRADPGADGEASRDDGATSSVSALKRLERSQWTDKMDLRFGFERLKEPGEKTGWLINMHPTEILDEDKRLGSAVDYYFIQDDGSRFKVALPYKPYFYIATRKGCEREVSSFLSKKFQGKIAKVETV... | [
{
"source_db": "GTEx",
"source_id": "Brain_Cerebellum",
"text": "POLE GENE_EXPRESSED_IN_TISSUE Brain_Cerebellum",
"confidence": 0.6303841024
}
] | {
"gene": "POLE",
"top_tissue": "Brain_Cerebellum",
"top_tpm": 76.88
} | 0.630384 |
no_tiss_00095 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is NRAS most highly expressed? | NRAS GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "NRAS",
"source_node_type": "GENE",
"source_node_label": "NRAS",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.6311424453,
"edge_source_db": "GTEx",
"target_node... | D | [
"A. Muscle_Skeletal",
"B. Heart_Left_Ventricle",
"C. Heart_Atrial_Appendage",
"D. Cells_EBV-transformed_lymphocytes"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "NRAS",
"source_db": "UniProt",
"payload": {
"accession": "P01111",
"sequence": "MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDLPTRTVDTKQAHELA... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "NRAS GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 0.6311424453
}
] | {
"gene": "NRAS",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 77.2891
} | 0.631142 |
no_tiss_00096 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is CHMP2B most highly expressed? | CHMP2B GENE_EXPRESSED_IN_TISSUE Artery_Tibial | {
"steps": [
{
"hop": 1,
"source_node_id": "CHMP2B",
"source_node_type": "GENE",
"source_node_label": "CHMP2B",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.624096969,
"edge_source_db": "GTEx",
"target_n... | D | [
"A. Heart_Left_Ventricle",
"B. Pancreas",
"C. Liver",
"D. Artery_Tibial"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "CHMP2B",
"source_db": "UniProt",
"payload": {
"accession": "Q9UQN3",
"sequence": "MASLFKKKTVDDVIKEQNRELRGTQRAIIRDRAALEKQEKQLELEIKKMAKIGNKEACKVLAKQLVHLRKQKTRTFAVSSKVTSMSTQTKVMNSQMKMAGAMSTTAKTMQAVNKKMDPQKTLQTMQNFQKEN... | [
{
"source_db": "GTEx",
"source_id": "Artery_Tibial",
"text": "CHMP2B GENE_EXPRESSED_IN_TISSUE Artery_Tibial",
"confidence": 0.624096969
}
] | {
"gene": "CHMP2B",
"top_tissue": "Artery_Tibial",
"top_tpm": 73.5696
} | 0.624097 |
no_tiss_00097 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is TP53 most highly expressed? | TP53 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "TP53",
"source_node_type": "GENE",
"source_node_label": "TP53",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.6228878952,
"edge_source_db": "GTEx",
"target_node... | C | [
"A. Brain_Hippocampus",
"B. Brain_Cerebellar_Hemisphere",
"C. Cells_EBV-transformed_lymphocytes",
"D. Brain_Cerebellum"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "TP53",
"source_db": "UniProt",
"payload": {
"accession": "P04637",
"sequence": "MEEPQSDPSVEPPLSQETFSDLWKLLPENNVLSPLPSQAMDDLMLSPDDIEQWFTEDPGPDEAPRMPEAAPPVAPAPAAPTPAAPAPAPSWPLSSSVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNKMF... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "TP53 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 0.6228878952
}
] | {
"gene": "TP53",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 72.9493
} | 0.622888 |
no_tiss_00098 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is VAPB most highly expressed? | VAPB GENE_EXPRESSED_IN_TISSUE Brain_Cerebellar_Hemisphere | {
"steps": [
{
"hop": 1,
"source_node_id": "VAPB",
"source_node_type": "GENE",
"source_node_label": "VAPB",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.5229552901,
"edge_source_db": "GTEx",
"target_node... | B | [
"A. Liver",
"B. Brain_Cerebellar_Hemisphere",
"C. Pancreas",
"D. Whole_Blood"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "VAPB",
"source_db": "UniProt",
"payload": {
"accession": "O95292",
"sequence": "MAKVEQVLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYCVRPNSGIIDAGASINVSVMLQPFDYDPNEKSKHKFMVQSMFAPTDTSDMEAVWKEAKPEDLMDSKLRCVFELPAENDKPHD... | [
{
"source_db": "GTEx",
"source_id": "Brain_Cerebellar_Hemisphere",
"text": "VAPB GENE_EXPRESSED_IN_TISSUE Brain_Cerebellar_Hemisphere",
"confidence": 0.5229552901
}
] | {
"gene": "VAPB",
"top_tissue": "Brain_Cerebellar_Hemisphere",
"top_tpm": 36.076
} | 0.522955 |
no_tiss_00099 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is BUB1B most highly expressed? | BUB1B GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "BUB1B",
"source_node_type": "GENE",
"source_node_label": "BUB1B",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.6191870218,
"edge_source_db": "GTEx",
"target_no... | A | [
"A. Cells_EBV-transformed_lymphocytes",
"B. Muscle_Skeletal",
"C. Brain_Hippocampus",
"D. Brain_Substantia_nigra"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "BUB1B",
"source_db": "UniProt",
"payload": {
"accession": "O60566",
"sequence": "MAAVKKEGGALSEAMSLEGDEWELSKENVQPLRQGRIMSTLQGALAQESACNNTLQQQKRAFEYEIRFYTGNDPLDVWDRYISWTEQNYPQGGKESNMSTLLERAVEALQGEKRYYSDPRFLNLWLKLGRLCN... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "BUB1B GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 0.6191870218
}
] | {
"gene": "BUB1B",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 71.0825
} | 0.619187 |
no_tiss_00100 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is CDK1 most highly expressed? | CDK1 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "CDK1",
"source_node_type": "GENE",
"source_node_label": "CDK1",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.6795622033,
"edge_source_db": "GTEx",
"target_node... | C | [
"A. Brain_Nucleus_accumbens_basal_ganglia",
"B. Liver",
"C. Cells_EBV-transformed_lymphocytes",
"D. Brain_Amygdala"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "CDK1",
"source_db": "UniProt",
"payload": {
"accession": "P06493",
"sequence": "MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNL... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "CDK1 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 0.6795622033
}
] | {
"gene": "CDK1",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 108.391
} | 0.679562 |
no_tiss_00101 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is CD2AP most highly expressed? | CD2AP GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "CD2AP",
"source_node_type": "GENE",
"source_node_label": "CD2AP",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.5497299012,
"edge_source_db": "GTEx",
"target_no... | B | [
"A. Brain_Anterior_cingulate_cortex_BA24",
"B. Cells_EBV-transformed_lymphocytes",
"C. Brain_Amygdala",
"D. Whole_Blood"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "CD2AP",
"source_db": "UniProt",
"payload": {
"accession": "Q9Y5K6",
"sequence": "MVDYIVEYDYDAVHDDELTIRVGEIIRNVKKLQEEGWLEGELNGRRGMFPDNFVKEIKRETEFKDDSLPIKRERHGNVASLVQRISTYGLPAGGIQPHPQTKNIKKKTKKRQCKVLFEYIPQNEDELELKVGD... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "CD2AP GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 0.5497299012
}
] | {
"gene": "CD2AP",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 43.6096
} | 0.54973 |
no_tiss_00102 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is CHEK2 most highly expressed? | CHEK2 GENE_EXPRESSED_IN_TISSUE Nerve_Tibial | {
"steps": [
{
"hop": 1,
"source_node_id": "CHEK2",
"source_node_type": "GENE",
"source_node_label": "CHEK2",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.3977285804,
"edge_source_db": "GTEx",
"target_no... | A | [
"A. Nerve_Tibial",
"B. Muscle_Skeletal",
"C. Brain_Cerebellum",
"D. Brain_Cerebellar_Hemisphere"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "CHEK2",
"source_db": "UniProt",
"payload": {
"accession": "O96017",
"sequence": "MSRESDVEAQQSHGSSACSQPHGSVTQSQGSSSQSQGISSSSTSTMPNSSQSSHSSSGTLSSLETVSTQELYSIPEDQEPEDQEPEEPTPAPWARLWALQDGFANLECVNDNYWFGRDKSCEYCFDEPLLKRT... | [
{
"source_db": "GTEx",
"source_id": "Nerve_Tibial",
"text": "CHEK2 GENE_EXPRESSED_IN_TISSUE Nerve_Tibial",
"confidence": 0.3977285804
}
] | {
"gene": "CHEK2",
"top_tissue": "Nerve_Tibial",
"top_tpm": 14.6084
} | 0.397729 |
no_tiss_00103 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is HAP1 most highly expressed? | HAP1 GENE_EXPRESSED_IN_TISSUE Brain_Hypothalamus | {
"steps": [
{
"hop": 1,
"source_node_id": "HAP1",
"source_node_type": "GENE",
"source_node_label": "HAP1",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.486703547,
"edge_source_db": "GTEx",
"target_node_... | B | [
"A. Cells_Cultured_fibroblasts",
"B. Brain_Hypothalamus",
"C. Heart_Left_Ventricle",
"D. Whole_Blood"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "HAP1",
"source_db": "UniProt",
"payload": {
"accession": "P54257",
"sequence": "MRPKRLGRCCAGSRLGPGDPAALTCAPSPSASPAPEPSAQPQARGTGQRVGSRATSGSQFLSEARTGARPASEAGAKAGARRPSAFSAIQGDVRSMPDNSDAPWTRFVFQGPFGSRATGRGTGKAAGIWKTPAA... | [
{
"source_db": "GTEx",
"source_id": "Brain_Hypothalamus",
"text": "HAP1 GENE_EXPRESSED_IN_TISSUE Brain_Hypothalamus",
"confidence": 0.486703547
}
] | {
"gene": "HAP1",
"top_tissue": "Brain_Hypothalamus",
"top_tpm": 27.8617
} | 0.486704 |
no_tiss_00104 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is SLC6A2 most highly expressed? | SLC6A2 GENE_EXPRESSED_IN_TISSUE Testis | {
"steps": [
{
"hop": 1,
"source_node_id": "SLC6A2",
"source_node_type": "GENE",
"source_node_label": "SLC6A2",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.2930054358,
"edge_source_db": "GTEx",
"target_... | C | [
"A. Whole_Blood",
"B. Pituitary",
"C. Testis",
"D. Spleen"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "SLC6A2",
"source_db": "UniProt",
"payload": {
"accession": "P23975",
"sequence": "MLLARMNPQVQPENNGADTGPEQPLRARKTAELLVVKERNGVQCLLAPRDGDAQPRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLFYMELALGQYNREGAATVWKICP... | [
{
"source_db": "GTEx",
"source_id": "Testis",
"text": "SLC6A2 GENE_EXPRESSED_IN_TISSUE Testis",
"confidence": 0.2930054358
}
] | {
"gene": "SLC6A2",
"top_tissue": "Testis",
"top_tpm": 6.57083
} | 0.293005 |
no_tiss_00105 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is ACVR1B most highly expressed? | ACVR1B GENE_EXPRESSED_IN_TISSUE Skin_Sun_Exposed_Lower_leg | {
"steps": [
{
"hop": 1,
"source_node_id": "ACVR1B",
"source_node_type": "GENE",
"source_node_label": "ACVR1B",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.6068893407,
"edge_source_db": "GTEx",
"target_... | D | [
"A. Cells_EBV-transformed_lymphocytes",
"B. Heart_Atrial_Appendage",
"C. Heart_Left_Ventricle",
"D. Skin_Sun_Exposed_Lower_leg"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "ACVR1B",
"source_db": "UniProt",
"payload": {
"accession": "P36896",
"sequence": "MAESAGASSFFPLVVLLLAGSGGSGPRGVQALLCACTSCLQANYTCETDGACMVSIFNLDGMEHHVRTCIPKVELVPAGKPFYCLSSEDLRNTHCCYTDYCNRIDLRVPSGHLKEPEHPSMWGPVELVGIIA... | [
{
"source_db": "GTEx",
"source_id": "Skin_Sun_Exposed_Lower_leg",
"text": "ACVR1B GENE_EXPRESSED_IN_TISSUE Skin_Sun_Exposed_Lower_leg",
"confidence": 0.6068893407
}
] | {
"gene": "ACVR1B",
"top_tissue": "Skin_Sun_Exposed_Lower_leg",
"top_tpm": 65.2112
} | 0.606889 |
no_tiss_00106 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is ETV4 most highly expressed? | ETV4 GENE_EXPRESSED_IN_TISSUE Pituitary | {
"steps": [
{
"hop": 1,
"source_node_id": "ETV4",
"source_node_type": "GENE",
"source_node_label": "ETV4",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.408657938,
"edge_source_db": "GTEx",
"target_node_... | D | [
"A. Whole_Blood",
"B. Muscle_Skeletal",
"C. Ovary",
"D. Pituitary"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "ETV4",
"source_db": "UniProt",
"payload": {
"accession": "P43268",
"sequence": "MERRMKAGYLDQQVPYTFSSKSPGNGSLREALIGPLGKLMDPGSLPPLDSEDLFQDLSHFQETWLAEAQVPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTDPALSCSRKPPLPYHHGEQCLYSSAYDPPR... | [
{
"source_db": "GTEx",
"source_id": "Pituitary",
"text": "ETV4 GENE_EXPRESSED_IN_TISSUE Pituitary",
"confidence": 0.408657938
}
] | {
"gene": "ETV4",
"top_tissue": "Pituitary",
"top_tpm": 15.8326
} | 0.408658 |
no_tiss_00107 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is ERG most highly expressed? | ERG GENE_EXPRESSED_IN_TISSUE Artery_Aorta | {
"steps": [
{
"hop": 1,
"source_node_id": "ERG",
"source_node_type": "GENE",
"source_node_label": "ERG",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.5656888765,
"edge_source_db": "GTEx",
"target_node_i... | B | [
"A. Cells_EBV-transformed_lymphocytes",
"B. Artery_Aorta",
"C. Cells_Cultured_fibroblasts",
"D. Whole_Blood"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "ERG",
"source_db": "UniProt",
"payload": {
"accession": "P11308",
"sequence": "MASTIKEALSVVSEDQSLFECAYGTPHLAKTEMTASSSSDYGQTSKMSPRVPQQDWLSQPPARVTIKMECNPSQVNGSRNSPDECSVAKGGKMVGSPDTVGMNYGSYMEEKHMPPPNMTTNERRVIVPADPTLWS... | [
{
"source_db": "GTEx",
"source_id": "Artery_Aorta",
"text": "ERG GENE_EXPRESSED_IN_TISSUE Artery_Aorta",
"confidence": 0.5656888765
}
] | {
"gene": "ERG",
"top_tissue": "Artery_Aorta",
"top_tpm": 48.8095
} | 0.565689 |
no_tiss_00108 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is NRAS most highly expressed? | NRAS GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "NRAS",
"source_node_type": "GENE",
"source_node_label": "NRAS",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.6311424453,
"edge_source_db": "GTEx",
"target_node... | C | [
"A. Heart_Atrial_Appendage",
"B. Muscle_Skeletal",
"C. Cells_EBV-transformed_lymphocytes",
"D. Heart_Left_Ventricle"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "NRAS",
"source_db": "UniProt",
"payload": {
"accession": "P01111",
"sequence": "MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDLPTRTVDTKQAHELA... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "NRAS GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 0.6311424453
}
] | {
"gene": "NRAS",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 77.2891
} | 0.631142 |
no_tiss_00109 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is MYC most highly expressed? | MYC GENE_EXPRESSED_IN_TISSUE Skin_Not_Sun_Exposed_Suprapubic | {
"steps": [
{
"hop": 1,
"source_node_id": "MYC",
"source_node_type": "GENE",
"source_node_label": "MYC",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.8254997906,
"edge_source_db": "GTEx",
"target_node_i... | D | [
"A. Brain_Putamen_basal_ganglia",
"B. Brain_Nucleus_accumbens_basal_ganglia",
"C. Brain_Caudate_basal_ganglia",
"D. Skin_Not_Sun_Exposed_Suprapubic"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "MYC",
"source_db": "UniProt",
"payload": {
"accession": "P01106",
"sequence": "MDFFRVVENQQPPATMPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPAPSEDIWKKFELLPTPPLSPSRRSGLCSPSYVAVTPFSLRGDNDGGGGSFSTADQLEMVTELLGGDMVNQSFICDPD... | [
{
"source_db": "GTEx",
"source_id": "Skin_Not_Sun_Exposed_Suprapubic",
"text": "MYC GENE_EXPRESSED_IN_TISSUE Skin_Not_Sun_Exposed_Suprapubic",
"confidence": 0.8254997906
}
] | {
"gene": "MYC",
"top_tissue": "Skin_Not_Sun_Exposed_Suprapubic",
"top_tpm": 298.818
} | 0.8255 |
no_tiss_00110 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is APP most highly expressed? | APP GENE_EXPRESSED_IN_TISSUE Brain_Frontal_Cortex_BA9 | {
"steps": [
{
"hop": 1,
"source_node_id": "APP",
"source_node_type": "GENE",
"source_node_label": "APP",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.9164822217,
"edge_source_db": "GTEx",
"target_node_i... | D | [
"A. Cells_EBV-transformed_lymphocytes",
"B. Muscle_Skeletal",
"C. Whole_Blood",
"D. Brain_Frontal_Cortex_BA9"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "APP",
"source_db": "UniProt",
"payload": {
"accession": "P05067",
"sequence": "MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKF... | [
{
"source_db": "GTEx",
"source_id": "Brain_Frontal_Cortex_BA9",
"text": "APP GENE_EXPRESSED_IN_TISSUE Brain_Frontal_Cortex_BA9",
"confidence": 0.9164822217
}
] | {
"gene": "APP",
"top_tissue": "Brain_Frontal_Cortex_BA9",
"top_tpm": 561.14
} | 0.916482 |
no_tiss_00111 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is ESR1 most highly expressed? | ESR1 GENE_EXPRESSED_IN_TISSUE Cervix_Endocervix | {
"steps": [
{
"hop": 1,
"source_node_id": "ESR1",
"source_node_type": "GENE",
"source_node_label": "ESR1",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.651105227,
"edge_source_db": "GTEx",
"target_node_... | C | [
"A. Whole_Blood",
"B. Brain_Putamen_basal_ganglia",
"C. Cervix_Endocervix",
"D. Cells_EBV-transformed_lymphocytes"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "ESR1",
"source_db": "UniProt",
"payload": {
"accession": "P03372",
"sequence": "MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLEN... | [
{
"source_db": "GTEx",
"source_id": "Cervix_Endocervix",
"text": "ESR1 GENE_EXPRESSED_IN_TISSUE Cervix_Endocervix",
"confidence": 0.651105227
}
] | {
"gene": "ESR1",
"top_tissue": "Cervix_Endocervix",
"top_tpm": 88.8666
} | 0.651105 |
no_tiss_00112 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is CHMP2B most highly expressed? | CHMP2B GENE_EXPRESSED_IN_TISSUE Artery_Tibial | {
"steps": [
{
"hop": 1,
"source_node_id": "CHMP2B",
"source_node_type": "GENE",
"source_node_label": "CHMP2B",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.624096969,
"edge_source_db": "GTEx",
"target_n... | B | [
"A. Heart_Left_Ventricle",
"B. Artery_Tibial",
"C. Pancreas",
"D. Liver"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "CHMP2B",
"source_db": "UniProt",
"payload": {
"accession": "Q9UQN3",
"sequence": "MASLFKKKTVDDVIKEQNRELRGTQRAIIRDRAALEKQEKQLELEIKKMAKIGNKEACKVLAKQLVHLRKQKTRTFAVSSKVTSMSTQTKVMNSQMKMAGAMSTTAKTMQAVNKKMDPQKTLQTMQNFQKEN... | [
{
"source_db": "GTEx",
"source_id": "Artery_Tibial",
"text": "CHMP2B GENE_EXPRESSED_IN_TISSUE Artery_Tibial",
"confidence": 0.624096969
}
] | {
"gene": "CHMP2B",
"top_tissue": "Artery_Tibial",
"top_tpm": 73.5696
} | 0.624097 |
no_tiss_00113 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is NF1 most highly expressed? | NF1 GENE_EXPRESSED_IN_TISSUE Cells_Cultured_fibroblasts | {
"steps": [
{
"hop": 1,
"source_node_id": "NF1",
"source_node_type": "GENE",
"source_node_label": "NF1",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.4250706929,
"edge_source_db": "GTEx",
"target_node_i... | A | [
"A. Cells_Cultured_fibroblasts",
"B. Heart_Left_Ventricle",
"C. Whole_Blood",
"D. Liver"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "NF1",
"source_db": "UniProt",
"payload": {
"accession": "P21359",
"sequence": "MAAHRPVEWVQAVVSRFDEQLPIKTGQQNTHTKVSTEHNKECLINISKYKFSLVISGLTTILKNVNNMRIFGEAAEKNLYLSQLIILDTLEKCLAGQPKDTMRLDETMLVKQLLPEICHFLHTCREGNQHAAELR... | [
{
"source_db": "GTEx",
"source_id": "Cells_Cultured_fibroblasts",
"text": "NF1 GENE_EXPRESSED_IN_TISSUE Cells_Cultured_fibroblasts",
"confidence": 0.4250706929
}
] | {
"gene": "NF1",
"top_tissue": "Cells_Cultured_fibroblasts",
"top_tpm": 17.8537
} | 0.425071 |
no_tiss_00114 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is SFRP4 most highly expressed? | SFRP4 GENE_EXPRESSED_IN_TISSUE Cervix_Endocervix | {
"steps": [
{
"hop": 1,
"source_node_id": "SFRP4",
"source_node_type": "GENE",
"source_node_label": "SFRP4",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.9168322383,
"edge_source_db": "GTEx",
"target_no... | A | [
"A. Cervix_Endocervix",
"B. Liver",
"C. Cells_EBV-transformed_lymphocytes",
"D. Whole_Blood"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "SFRP4",
"source_db": "UniProt",
"payload": {
"accession": "Q6FHJ7",
"sequence": "MFLSILVALCLWLHLALGVRGAPCEAVRIPMCRHMPWNITRMPNHLHHSTQENAILAIEQYEELVDVNCSAVLRFFLCAMYAPICTLEFLHDPIKPCKSVCQRARDDCEPLMKMYNHSWPESLACDELPVYDR... | [
{
"source_db": "GTEx",
"source_id": "Cervix_Endocervix",
"text": "SFRP4 GENE_EXPRESSED_IN_TISSUE Cervix_Endocervix",
"confidence": 0.9168322383
}
] | {
"gene": "SFRP4",
"top_tissue": "Cervix_Endocervix",
"top_tpm": 562.501
} | 0.916832 |
no_tiss_00115 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is JPH3 most highly expressed? | JPH3 GENE_EXPRESSED_IN_TISSUE Brain_Cortex | {
"steps": [
{
"hop": 1,
"source_node_id": "JPH3",
"source_node_type": "GENE",
"source_node_label": "JPH3",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.6860123739,
"edge_source_db": "GTEx",
"target_node... | D | [
"A. Muscle_Skeletal",
"B. Whole_Blood",
"C. Cells_Cultured_fibroblasts",
"D. Brain_Cortex"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "JPH3",
"source_db": "UniProt",
"payload": {
"accession": "Q8WXH2",
"sequence": "MSSGGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGVYTWPSGNTYQGTWAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQW... | [
{
"source_db": "GTEx",
"source_id": "Brain_Cortex",
"text": "JPH3 GENE_EXPRESSED_IN_TISSUE Brain_Cortex",
"confidence": 0.6860123739
}
] | {
"gene": "JPH3",
"top_tissue": "Brain_Cortex",
"top_tpm": 113.376
} | 0.686012 |
no_tiss_00116 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is ADRA2C most highly expressed? | ADRA2C GENE_EXPRESSED_IN_TISSUE Cervix_Endocervix | {
"steps": [
{
"hop": 1,
"source_node_id": "ADRA2C",
"source_node_type": "GENE",
"source_node_label": "ADRA2C",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.7760278414,
"edge_source_db": "GTEx",
"target_... | A | [
"A. Cervix_Endocervix",
"B. Cells_EBV-transformed_lymphocytes",
"C. Liver",
"D. Whole_Blood"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "ADRA2C",
"source_db": "UniProt",
"payload": {
"accession": "P18825",
"sequence": "MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDV... | [
{
"source_db": "GTEx",
"source_id": "Cervix_Endocervix",
"text": "ADRA2C GENE_EXPRESSED_IN_TISSUE Cervix_Endocervix",
"confidence": 0.7760278414
}
] | {
"gene": "ADRA2C",
"top_tissue": "Cervix_Endocervix",
"top_tpm": 212.02
} | 0.776028 |
no_tiss_00117 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is MAPK1 most highly expressed? | MAPK1 GENE_EXPRESSED_IN_TISSUE Brain_Nucleus_accumbens_basal_ganglia | {
"steps": [
{
"hop": 1,
"source_node_id": "MAPK1",
"source_node_type": "GENE",
"source_node_label": "MAPK1",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.6007341152,
"edge_source_db": "GTEx",
"target_no... | B | [
"A. Heart_Left_Ventricle",
"B. Brain_Nucleus_accumbens_basal_ganglia",
"C. Pancreas",
"D. Liver"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "MAPK1",
"source_db": "UniProt",
"payload": {
"accession": "P28482",
"sequence": "MAAAAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQI... | [
{
"source_db": "GTEx",
"source_id": "Brain_Nucleus_accumbens_basal_ganglia",
"text": "MAPK1 GENE_EXPRESSED_IN_TISSUE Brain_Nucleus_accumbens_basal_ganglia",
"confidence": 0.6007341152
}
] | {
"gene": "MAPK1",
"top_tissue": "Brain_Nucleus_accumbens_basal_ganglia",
"top_tpm": 62.4546
} | 0.600734 |
no_tiss_00118 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is BRAF most highly expressed? | BRAF GENE_EXPRESSED_IN_TISSUE Brain_Cerebellar_Hemisphere | {
"steps": [
{
"hop": 1,
"source_node_id": "BRAF",
"source_node_type": "GENE",
"source_node_label": "BRAF",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.4852843643,
"edge_source_db": "GTEx",
"target_node... | D | [
"A. Heart_Left_Ventricle",
"B. Pancreas",
"C. Liver",
"D. Brain_Cerebellar_Hemisphere"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "BRAF",
"source_db": "UniProt",
"payload": {
"accession": "P15056",
"sequence": "MAALSGGGGGGAEPGQALFNGDMEPEAGAGAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLESLGNGTDFSVSSSASMDTVTSSSSSSLSVLPSS... | [
{
"source_db": "GTEx",
"source_id": "Brain_Cerebellar_Hemisphere",
"text": "BRAF GENE_EXPRESSED_IN_TISSUE Brain_Cerebellar_Hemisphere",
"confidence": 0.4852843643
}
] | {
"gene": "BRAF",
"top_tissue": "Brain_Cerebellar_Hemisphere",
"top_tpm": 27.5801
} | 0.485284 |
no_tiss_00119 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is NRAS most highly expressed? | NRAS GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "NRAS",
"source_node_type": "GENE",
"source_node_label": "NRAS",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.6311424453,
"edge_source_db": "GTEx",
"target_node... | D | [
"A. Heart_Left_Ventricle",
"B. Muscle_Skeletal",
"C. Heart_Atrial_Appendage",
"D. Cells_EBV-transformed_lymphocytes"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "NRAS",
"source_db": "UniProt",
"payload": {
"accession": "P01111",
"sequence": "MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDLPTRTVDTKQAHELA... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "NRAS GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 0.6311424453
}
] | {
"gene": "NRAS",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 77.2891
} | 0.631142 |
no_tiss_00120 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is KLK3 most highly expressed? | KLK3 GENE_EXPRESSED_IN_TISSUE Prostate | {
"steps": [
{
"hop": 1,
"source_node_id": "KLK3",
"source_node_type": "GENE",
"source_node_label": "KLK3",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 1,
"edge_source_db": "GTEx",
"target_node_id": "Pros... | B | [
"A. Brain_Spinal_cord_cervical_c-1",
"B. Prostate",
"C. Brain_Caudate_basal_ganglia",
"D. Brain_Putamen_basal_ganglia"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "KLK3",
"source_db": "UniProt",
"payload": {
"accession": "P07288",
"sequence": "MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTD... | [
{
"source_db": "GTEx",
"source_id": "Prostate",
"text": "KLK3 GENE_EXPRESSED_IN_TISSUE Prostate",
"confidence": 1
}
] | {
"gene": "KLK3",
"top_tissue": "Prostate",
"top_tpm": 4285.71
} | 1 |
no_tiss_00121 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is LRRK2 most highly expressed? | LRRK2 GENE_EXPRESSED_IN_TISSUE Lung | {
"steps": [
{
"hop": 1,
"source_node_id": "LRRK2",
"source_node_type": "GENE",
"source_node_label": "LRRK2",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.4955052268,
"edge_source_db": "GTEx",
"target_no... | B | [
"A. Heart_Left_Ventricle",
"B. Lung",
"C. Testis",
"D. Liver"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "LRRK2",
"source_db": "UniProt",
"payload": {
"accession": "Q5S007",
"sequence": "MASGSCQGCEEDEETLKKLIVRLNNVQEGKQIETLVQILEDLLVFTYSERASKLFQGKNIHVPLLIVLDSYMRVASVQQVGWSLLCKLIEVCPGTMQSLMGPQDVGNDWEVLGVHQLILKMLTVHNASVNLSV... | [
{
"source_db": "GTEx",
"source_id": "Lung",
"text": "LRRK2 GENE_EXPRESSED_IN_TISSUE Lung",
"confidence": 0.4955052268
}
] | {
"gene": "LRRK2",
"top_tissue": "Lung",
"top_tpm": 29.6712
} | 0.495505 |
no_tiss_00122 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is AVPR1A most highly expressed? | AVPR1A GENE_EXPRESSED_IN_TISSUE Artery_Tibial | {
"steps": [
{
"hop": 1,
"source_node_id": "AVPR1A",
"source_node_type": "GENE",
"source_node_label": "AVPR1A",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.5470461588,
"edge_source_db": "GTEx",
"target_... | B | [
"A. Whole_Blood",
"B. Artery_Tibial",
"C. Cells_EBV-transformed_lymphocytes",
"D. Cells_Cultured_fibroblasts"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "AVPR1A",
"source_db": "UniProt",
"payload": {
"accession": "P37288",
"sequence": "MRLSAGPDAGPSGNSSPWWPLATGAGNTSREAEALGEGNGPPRDVRNEELAKLEIAVLAVTFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGPDWLCRVVKHLQV... | [
{
"source_db": "GTEx",
"source_id": "Artery_Tibial",
"text": "AVPR1A GENE_EXPRESSED_IN_TISSUE Artery_Tibial",
"confidence": 0.5470461588
}
] | {
"gene": "AVPR1A",
"top_tissue": "Artery_Tibial",
"top_tpm": 42.7901
} | 0.547046 |
no_tiss_00123 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is CD44 most highly expressed? | CD44 GENE_EXPRESSED_IN_TISSUE Skin_Not_Sun_Exposed_Suprapubic | {
"steps": [
{
"hop": 1,
"source_node_id": "CD44",
"source_node_type": "GENE",
"source_node_label": "CD44",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.7901935614,
"edge_source_db": "GTEx",
"target_node... | A | [
"A. Skin_Not_Sun_Exposed_Suprapubic",
"B. Brain_Putamen_basal_ganglia",
"C. Brain_Nucleus_accumbens_basal_ganglia",
"D. Brain_Frontal_Cortex_BA9"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "CD44",
"source_db": "UniProt",
"payload": {
"accession": "P16070",
"sequence": "MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTLPTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTD... | [
{
"source_db": "GTEx",
"source_id": "Skin_Not_Sun_Exposed_Suprapubic",
"text": "CD44 GENE_EXPRESSED_IN_TISSUE Skin_Not_Sun_Exposed_Suprapubic",
"confidence": 0.7901935614
}
] | {
"gene": "CD44",
"top_tissue": "Skin_Not_Sun_Exposed_Suprapubic",
"top_tpm": 233.922
} | 0.790194 |
no_tiss_00124 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is CCND1 most highly expressed? | CCND1 GENE_EXPRESSED_IN_TISSUE Cells_Cultured_fibroblasts | {
"steps": [
{
"hop": 1,
"source_node_id": "CCND1",
"source_node_type": "GENE",
"source_node_label": "CCND1",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.7690562087,
"edge_source_db": "GTEx",
"target_no... | C | [
"A. Whole_Blood",
"B. Muscle_Skeletal",
"C. Cells_Cultured_fibroblasts",
"D. Testis"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "CCND1",
"source_db": "UniProt",
"payload": {
"accession": "P24385",
"sequence": "MEHQLLCCEVETIRRAYPDANLLNDRVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIR... | [
{
"source_db": "GTEx",
"source_id": "Cells_Cultured_fibroblasts",
"text": "CCND1 GENE_EXPRESSED_IN_TISSUE Cells_Cultured_fibroblasts",
"confidence": 0.7690562087
}
] | {
"gene": "CCND1",
"top_tissue": "Cells_Cultured_fibroblasts",
"top_tpm": 202.003
} | 0.769056 |
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