id string | task_type string | pipeline string | difficulty string | num_hops int64 | question string | context string | reasoning_chain dict | answer string | choices list | modalities list | modality_data list | evidence list | metadata unknown | path_confidence_score float64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
no_tiss_00125 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is HTT most highly expressed? | HTT GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "HTT",
"source_node_type": "GENE",
"source_node_label": "HTT",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.601818339,
"edge_source_db": "GTEx",
"target_node_id... | B | [
"A. Heart_Left_Ventricle",
"B. Cells_EBV-transformed_lymphocytes",
"C. Whole_Blood",
"D. Heart_Atrial_Appendage"
] | [
"expression",
"protein_sequence"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "HTT",
"source_db": "UniProt",
"payload": {
"accession": "P42858",
"sequence": "MATLEKLMKAFESLKSFQQQQQQQQQQQQQQQQQQQQQPPPPPPPPPPPQLPQPPPQAQPLLPQPQPPPPPPPPPPGPAVAEEPLHRPKKELSATKKDRVNHCLTICENIVAQSVRNSPEFQKLLGIAMELFLLC... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "HTT GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 0.601818339
}
] | {
"gene": "HTT",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 62.9317
} | 0.601818 |
no_tiss_00126 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is ACTB most highly expressed? | ACTB GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "ACTB",
"source_node_type": "GENE",
"source_node_label": "ACTB",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 1,
"edge_source_db": "GTEx",
"target_node_id": "Cell... | A | [
"A. Cells_EBV-transformed_lymphocytes",
"B. Pancreas",
"C. Muscle_Skeletal",
"D. Heart_Left_Ventricle"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "ACTB",
"source_db": "UniProt",
"payload": {
"accession": "P60709",
"sequence": "MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYV... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "ACTB GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 1
}
] | {
"gene": "ACTB",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 11629.4
} | 1 |
no_tiss_00127 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is APOE most highly expressed? | APOE GENE_EXPRESSED_IN_TISSUE Adrenal_Gland | {
"steps": [
{
"hop": 1,
"source_node_id": "APOE",
"source_node_type": "GENE",
"source_node_label": "APOE",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 1,
"edge_source_db": "GTEx",
"target_node_id": "Adre... | D | [
"A. Whole_Blood",
"B. Muscle_Skeletal",
"C. Cells_EBV-transformed_lymphocytes",
"D. Adrenal_Gland"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "APOE",
"source_db": "UniProt",
"payload": {
"accession": "P02649",
"sequence": "MKVLWAALLVTFLAGCQAKVEQAVETEPEPELRQQTEWQSGQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLV... | [
{
"source_db": "GTEx",
"source_id": "Adrenal_Gland",
"text": "APOE GENE_EXPRESSED_IN_TISSUE Adrenal_Gland",
"confidence": 1
}
] | {
"gene": "APOE",
"top_tissue": "Adrenal_Gland",
"top_tpm": 3543.25
} | 1 |
no_tiss_00128 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is TMPRSS2 most highly expressed? | TMPRSS2 GENE_EXPRESSED_IN_TISSUE Prostate | {
"steps": [
{
"hop": 1,
"source_node_id": "TMPRSS2",
"source_node_type": "GENE",
"source_node_label": "TMPRSS2",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.7509013867,
"edge_source_db": "GTEx",
"targe... | A | [
"A. Prostate",
"B. Muscle_Skeletal",
"C. Brain_Spinal_cord_cervical_c-1",
"D. Heart_Left_Ventricle"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "TMPRSS2",
"source_db": "UniProt",
"payload": {
"accession": "O15393",
"sequence": "MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSN... | [
{
"source_db": "GTEx",
"source_id": "Prostate",
"text": "TMPRSS2 GENE_EXPRESSED_IN_TISSUE Prostate",
"confidence": 0.7509013867
}
] | {
"gene": "TMPRSS2",
"top_tissue": "Prostate",
"top_tpm": 178.073
} | 0.750901 |
no_tiss_00129 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is ATM most highly expressed? | ATM GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "ATM",
"source_node_type": "GENE",
"source_node_label": "ATM",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.4475955638,
"edge_source_db": "GTEx",
"target_node_i... | C | [
"A. Muscle_Skeletal",
"B. Brain_Anterior_cingulate_cortex_BA24",
"C. Cells_EBV-transformed_lymphocytes",
"D. Heart_Left_Ventricle"
] | [
"expression",
"protein_sequence"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "ATM",
"source_db": "UniProt",
"payload": {
"accession": "Q13315",
"sequence": "MSLVLNDLLICCRQLEHDRATERKKEVEKFKRLIRDPETIKHLDRHSDSKQGKYLNWDAVFRFLQKYIQKETECLRIAKPNVSASTQASRQKKMQEISSLVKYFIKCANRRAPRLKCQELLNYIMDTVKDSSNGA... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "ATM GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 0.4475955638
}
] | {
"gene": "ATM",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 21.0283
} | 0.447596 |
no_tiss_00130 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is ADAM10 most highly expressed? | ADAM10 GENE_EXPRESSED_IN_TISSUE Cells_Cultured_fibroblasts | {
"steps": [
{
"hop": 1,
"source_node_id": "ADAM10",
"source_node_type": "GENE",
"source_node_label": "ADAM10",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.5245177869,
"edge_source_db": "GTEx",
"target_... | B | [
"A. Pancreas",
"B. Cells_Cultured_fibroblasts",
"C. Heart_Left_Ventricle",
"D. Muscle_Skeletal"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "ADAM10",
"source_db": "UniProt",
"payload": {
"accession": "O14672",
"sequence": "MVLLRVLILLLSWAAGMGGQYGNPLNKYIRHYEGLSYNVDSLHQKHQRAKRAVSHEDQFLRLDFHAHGRHFNLRMKRDTSLFSDEFKVETSNKVLDYDTSHIYTGHIYGEEGSFSHGSVIDGRFEGFIQTRG... | [
{
"source_db": "GTEx",
"source_id": "Cells_Cultured_fibroblasts",
"text": "ADAM10 GENE_EXPRESSED_IN_TISSUE Cells_Cultured_fibroblasts",
"confidence": 0.5245177869
}
] | {
"gene": "ADAM10",
"top_tissue": "Cells_Cultured_fibroblasts",
"top_tpm": 36.4784
} | 0.524518 |
no_tiss_00131 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is ADAM10 most highly expressed? | ADAM10 GENE_EXPRESSED_IN_TISSUE Cells_Cultured_fibroblasts | {
"steps": [
{
"hop": 1,
"source_node_id": "ADAM10",
"source_node_type": "GENE",
"source_node_label": "ADAM10",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.5245177869,
"edge_source_db": "GTEx",
"target_... | D | [
"A. Pancreas",
"B. Muscle_Skeletal",
"C. Heart_Left_Ventricle",
"D. Cells_Cultured_fibroblasts"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "ADAM10",
"source_db": "UniProt",
"payload": {
"accession": "O14672",
"sequence": "MVLLRVLILLLSWAAGMGGQYGNPLNKYIRHYEGLSYNVDSLHQKHQRAKRAVSHEDQFLRLDFHAHGRHFNLRMKRDTSLFSDEFKVETSNKVLDYDTSHIYTGHIYGEEGSFSHGSVIDGRFEGFIQTRG... | [
{
"source_db": "GTEx",
"source_id": "Cells_Cultured_fibroblasts",
"text": "ADAM10 GENE_EXPRESSED_IN_TISSUE Cells_Cultured_fibroblasts",
"confidence": 0.5245177869
}
] | {
"gene": "ADAM10",
"top_tissue": "Cells_Cultured_fibroblasts",
"top_tpm": 36.4784
} | 0.524518 |
no_tiss_00132 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is IL22 most highly expressed? | IL22 GENE_EXPRESSED_IN_TISSUE Testis | {
"steps": [
{
"hop": 1,
"source_node_id": "IL22",
"source_node_type": "GENE",
"source_node_label": "IL22",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.0358106216,
"edge_source_db": "GTEx",
"target_node... | C | [
"A. Vagina",
"B. Uterus",
"C. Testis",
"D. Whole_Blood"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "IL22",
"source_db": "UniProt",
"payload": {
"accession": "Q9GZX6",
"sequence": "MAALQKSVSSFLMGTLATSCLLLLALLVQGGAAAPISSHCRLDKSNFQQPYITNRTFMLAKEASLADNNTDVRLIGEKLFHGVSMSERCYLMKQVLNFTLEEVLFPQSDRFQPYMQEVVPFLARLSNRLSTCHI... | [
{
"source_db": "GTEx",
"source_id": "Testis",
"text": "IL22 GENE_EXPRESSED_IN_TISSUE Testis",
"confidence": 0.0358106216
}
] | {
"gene": "IL22",
"top_tissue": "Testis",
"top_tpm": 0.2807
} | 0.035811 |
no_tiss_00133 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is MLH1 most highly expressed? | MLH1 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "MLH1",
"source_node_type": "GENE",
"source_node_label": "MLH1",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.5648507033,
"edge_source_db": "GTEx",
"target_node... | B | [
"A. Pancreas",
"B. Cells_EBV-transformed_lymphocytes",
"C. Whole_Blood",
"D. Brain_Putamen_basal_ganglia"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "MLH1",
"source_db": "UniProt",
"payload": {
"accession": "P40692",
"sequence": "MSFVAGVIRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAKSTSIQVIVKEGGLKLIQIQDNGTGIRKEDLDIVCERFTTSKLQSFEDLASISTYGFRGEALASISHVAHVTITTKTADGKCAYRASYSDGK... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "MLH1 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 0.5648507033
}
] | {
"gene": "MLH1",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 48.5219
} | 0.564851 |
no_tiss_00134 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is HGF most highly expressed? | HGF GENE_EXPRESSED_IN_TISSUE Lung | {
"steps": [
{
"hop": 1,
"source_node_id": "HGF",
"source_node_type": "GENE",
"source_node_label": "HGF",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.4109367043,
"edge_source_db": "GTEx",
"target_node_i... | C | [
"A. Brain_Cerebellar_Hemisphere",
"B. Brain_Putamen_basal_ganglia",
"C. Lung",
"D. Cells_EBV-transformed_lymphocytes"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "HGF",
"source_db": "UniProt",
"payload": {
"accession": "P14210",
"sequence": "MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIKTKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYENKDYIRNCIIGKGRS... | [
{
"source_db": "GTEx",
"source_id": "Lung",
"text": "HGF GENE_EXPRESSED_IN_TISSUE Lung",
"confidence": 0.4109367043
}
] | {
"gene": "HGF",
"top_tissue": "Lung",
"top_tpm": 16.0997
} | 0.410937 |
no_tiss_00135 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is MSH6 most highly expressed? | MSH6 GENE_EXPRESSED_IN_TISSUE Ovary | {
"steps": [
{
"hop": 1,
"source_node_id": "MSH6",
"source_node_type": "GENE",
"source_node_label": "MSH6",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.5380127125,
"edge_source_db": "GTEx",
"target_node... | C | [
"A. Whole_Blood",
"B. Heart_Left_Ventricle",
"C. Ovary",
"D. Brain_Anterior_cingulate_cortex_BA24"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "MSH6",
"source_db": "UniProt",
"payload": {
"accession": "P52701",
"sequence": "MSRQSTLYSFFPKSPALSDANKASARASREGGRAAAAPGASPSPGGDAAWSEAGPGPRPLARSASPPKAKNLNGGLRRSVAPAAPTSCDFSPGDLVWAKMEGYPWWPCLVYNHPFDGTFIREKGKSVRVHVQFF... | [
{
"source_db": "GTEx",
"source_id": "Ovary",
"text": "MSH6 GENE_EXPRESSED_IN_TISSUE Ovary",
"confidence": 0.5380127125
}
] | {
"gene": "MSH6",
"top_tissue": "Ovary",
"top_tpm": 40.1407
} | 0.538013 |
no_tiss_00136 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is CDK1 most highly expressed? | CDK1 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "CDK1",
"source_node_type": "GENE",
"source_node_label": "CDK1",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.6795622033,
"edge_source_db": "GTEx",
"target_node... | A | [
"A. Cells_EBV-transformed_lymphocytes",
"B. Brain_Amygdala",
"C. Liver",
"D. Brain_Nucleus_accumbens_basal_ganglia"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "CDK1",
"source_db": "UniProt",
"payload": {
"accession": "P06493",
"sequence": "MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNL... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "CDK1 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 0.6795622033
}
] | {
"gene": "CDK1",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 108.391
} | 0.679562 |
no_tiss_00137 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is SLC6A2 most highly expressed? | SLC6A2 GENE_EXPRESSED_IN_TISSUE Testis | {
"steps": [
{
"hop": 1,
"source_node_id": "SLC6A2",
"source_node_type": "GENE",
"source_node_label": "SLC6A2",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.2930054358,
"edge_source_db": "GTEx",
"target_... | D | [
"A. Pituitary",
"B. Spleen",
"C. Whole_Blood",
"D. Testis"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "SLC6A2",
"source_db": "UniProt",
"payload": {
"accession": "P23975",
"sequence": "MLLARMNPQVQPENNGADTGPEQPLRARKTAELLVVKERNGVQCLLAPRDGDAQPRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLFYMELALGQYNREGAATVWKICP... | [
{
"source_db": "GTEx",
"source_id": "Testis",
"text": "SLC6A2 GENE_EXPRESSED_IN_TISSUE Testis",
"confidence": 0.2930054358
}
] | {
"gene": "SLC6A2",
"top_tissue": "Testis",
"top_tpm": 6.57083
} | 0.293005 |
no_tiss_00138 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is CDKN1A most highly expressed? | CDKN1A GENE_EXPRESSED_IN_TISSUE Artery_Aorta | {
"steps": [
{
"hop": 1,
"source_node_id": "CDKN1A",
"source_node_type": "GENE",
"source_node_label": "CDKN1A",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.8738858036,
"edge_source_db": "GTEx",
"target_... | D | [
"A. Brain_Cerebellar_Hemisphere",
"B. Brain_Putamen_basal_ganglia",
"C. Brain_Cerebellum",
"D. Artery_Aorta"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "CDKN1A",
"source_db": "UniProt",
"payload": {
"accession": "P38936",
"sequence": "MSEPAGDVRQNPCGSKACRRLFGPVDSEQLSRDCDALMAGCIQEARERWNFDFVTETPLEGDFAWERVRGLGLPKLYLPTGPRRGRDELGGGRRPGTSPALLQGTAEEDHVDLSLSCTLVPRSGEQAEGSPG... | [
{
"source_db": "GTEx",
"source_id": "Artery_Aorta",
"text": "CDKN1A GENE_EXPRESSED_IN_TISSUE Artery_Aorta",
"confidence": 0.8738858036
}
] | {
"gene": "CDKN1A",
"top_tissue": "Artery_Aorta",
"top_tpm": 417.829
} | 0.873886 |
no_tiss_00139 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is FOLH1 most highly expressed? | FOLH1 GENE_EXPRESSED_IN_TISSUE Brain_Spinal_cord_cervical_c-1 | {
"steps": [
{
"hop": 1,
"source_node_id": "FOLH1",
"source_node_type": "GENE",
"source_node_label": "FOLH1",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.596747858,
"edge_source_db": "GTEx",
"target_nod... | C | [
"A. Whole_Blood",
"B. Cells_Cultured_fibroblasts",
"C. Brain_Spinal_cord_cervical_c-1",
"D. Cells_EBV-transformed_lymphocytes"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "FOLH1",
"source_db": "UniProt",
"payload": {
"accession": "Q04609",
"sequence": "MWNLLHETDSAVATARRPRWLCAGALVLAGGFFLLGFLFGWFIKSSNEATNITPKHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINE... | [
{
"source_db": "GTEx",
"source_id": "Brain_Spinal_cord_cervical_c-1",
"text": "FOLH1 GENE_EXPRESSED_IN_TISSUE Brain_Spinal_cord_cervical_c-1",
"confidence": 0.596747858
}
] | {
"gene": "FOLH1",
"top_tissue": "Brain_Spinal_cord_cervical_c-1",
"top_tpm": 60.7309
} | 0.596748 |
no_tiss_00140 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is AKAP11 most highly expressed? | AKAP11 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "AKAP11",
"source_node_type": "GENE",
"source_node_label": "AKAP11",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.55130567,
"edge_source_db": "GTEx",
"target_no... | A | [
"A. Cells_EBV-transformed_lymphocytes",
"B. Heart_Left_Ventricle",
"C. Liver",
"D. Whole_Blood"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "AKAP11",
"source_db": "UniProt",
"payload": {
"accession": "Q9UKA4",
"sequence": "MATFRNNHMKTKASVRKSFSEDVFQSVKSLLQSQKELCSVTAEDCLQQDEHANLTEVTFLGFNEETDAAHIQDLAAVSLELPDILNSLHFCSLNENEIICMKNINKPLDISSDPLNQSHPSGMLCVMRVSPT... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "AKAP11 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 0.55130567
}
] | {
"gene": "AKAP11",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 44.0979
} | 0.551306 |
no_tiss_00141 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is ETV1 most highly expressed? | ETV1 GENE_EXPRESSED_IN_TISSUE Brain_Cerebellar_Hemisphere | {
"steps": [
{
"hop": 1,
"source_node_id": "ETV1",
"source_node_type": "GENE",
"source_node_label": "ETV1",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.7480657733,
"edge_source_db": "GTEx",
"target_node... | B | [
"A. Whole_Blood",
"B. Brain_Cerebellar_Hemisphere",
"C. Cells_EBV-transformed_lymphocytes",
"D. Muscle_Skeletal"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "ETV1",
"source_db": "UniProt",
"payload": {
"accession": "P50549",
"sequence": "MDGFYDQQVPYMVTNSQRGRNCNEKPTNVRKRKFINRDLAHDSEELFQDLSQLQETWLAEAQVPDNDEQFVPDYQAESLAFHGLPLKIKKEPHSPCSEISSACSQEQPFKFSYGEKCLYNVSAYDQKPQVGMRP... | [
{
"source_db": "GTEx",
"source_id": "Brain_Cerebellar_Hemisphere",
"text": "ETV1 GENE_EXPRESSED_IN_TISSUE Brain_Cerebellar_Hemisphere",
"confidence": 0.7480657733
}
] | {
"gene": "ETV1",
"top_tissue": "Brain_Cerebellar_Hemisphere",
"top_tpm": 174.599
} | 0.748066 |
no_tiss_00142 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is UBQLN2 most highly expressed? | UBQLN2 GENE_EXPRESSED_IN_TISSUE Brain_Cerebellar_Hemisphere | {
"steps": [
{
"hop": 1,
"source_node_id": "UBQLN2",
"source_node_type": "GENE",
"source_node_label": "UBQLN2",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.6278140921,
"edge_source_db": "GTEx",
"target_... | C | [
"A. Testis",
"B. Pancreas",
"C. Brain_Cerebellar_Hemisphere",
"D. Kidney_Cortex"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "UBQLN2",
"source_db": "UniProt",
"payload": {
"accession": "Q9UHD9",
"sequence": "MAENGESSGPPRPSRGPAAAQGSAAAPAEPKIIKVTVKTPKEKEEFAVPENSSVQQFKEAISKRFKSQTDQLVLIFAGKILKDQDTLIQHGIHDGLTVHLVIKSQNRPQGQSTQPSNAAGTNTTSASTPRSN... | [
{
"source_db": "GTEx",
"source_id": "Brain_Cerebellar_Hemisphere",
"text": "UBQLN2 GENE_EXPRESSED_IN_TISSUE Brain_Cerebellar_Hemisphere",
"confidence": 0.6278140921
}
] | {
"gene": "UBQLN2",
"top_tissue": "Brain_Cerebellar_Hemisphere",
"top_tpm": 75.5094
} | 0.627814 |
no_tiss_00143 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is SLC6A2 most highly expressed? | SLC6A2 GENE_EXPRESSED_IN_TISSUE Testis | {
"steps": [
{
"hop": 1,
"source_node_id": "SLC6A2",
"source_node_type": "GENE",
"source_node_label": "SLC6A2",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.2930054358,
"edge_source_db": "GTEx",
"target_... | A | [
"A. Testis",
"B. Spleen",
"C. Whole_Blood",
"D. Pituitary"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "SLC6A2",
"source_db": "UniProt",
"payload": {
"accession": "P23975",
"sequence": "MLLARMNPQVQPENNGADTGPEQPLRARKTAELLVVKERNGVQCLLAPRDGDAQPRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLFYMELALGQYNREGAATVWKICP... | [
{
"source_db": "GTEx",
"source_id": "Testis",
"text": "SLC6A2 GENE_EXPRESSED_IN_TISSUE Testis",
"confidence": 0.2930054358
}
] | {
"gene": "SLC6A2",
"top_tissue": "Testis",
"top_tpm": 6.57083
} | 0.293005 |
no_tiss_00144 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is REST most highly expressed? | REST GENE_EXPRESSED_IN_TISSUE Cells_Cultured_fibroblasts | {
"steps": [
{
"hop": 1,
"source_node_id": "REST",
"source_node_type": "GENE",
"source_node_label": "REST",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.4317375131,
"edge_source_db": "GTEx",
"target_node... | A | [
"A. Cells_Cultured_fibroblasts",
"B. Brain_Cerebellum",
"C. Brain_Cerebellar_Hemisphere",
"D. Brain_Frontal_Cortex_BA9"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "REST",
"source_db": "UniProt",
"payload": {
"accession": "Q13127",
"sequence": "MATQVMGQSSGGGGLFTSSGNIGMALPNDMYDLHDLSKAELAAPQLIMLANVALTGEVNGSCCDYLVGEERQMAELMPVGDNNFSDSEEGEGLEESADIKGEPHGLENMELRSLELSVVEPQPVFEASGAPDIY... | [
{
"source_db": "GTEx",
"source_id": "Cells_Cultured_fibroblasts",
"text": "REST GENE_EXPRESSED_IN_TISSUE Cells_Cultured_fibroblasts",
"confidence": 0.4317375131
}
] | {
"gene": "REST",
"top_tissue": "Cells_Cultured_fibroblasts",
"top_tpm": 18.7424
} | 0.431738 |
no_tiss_00145 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is PDE10A most highly expressed? | PDE10A GENE_EXPRESSED_IN_TISSUE Brain_Caudate_basal_ganglia | {
"steps": [
{
"hop": 1,
"source_node_id": "PDE10A",
"source_node_type": "GENE",
"source_node_label": "PDE10A",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.369352058,
"edge_source_db": "GTEx",
"target_n... | A | [
"A. Brain_Caudate_basal_ganglia",
"B. Whole_Blood",
"C. Cells_Cultured_fibroblasts",
"D. Cells_EBV-transformed_lymphocytes"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "PDE10A",
"source_db": "UniProt",
"payload": {
"accession": "Q9Y233",
"sequence": "MASLEEPLAPRPQGPLPAAGDEPGCGPGKLRPEPRLSAAGGGSAAGPGPAPEWPGRGRAERAAPPRPPLSSAGRPSPAGGPGALSARGGGCGWVAARAPLALAFSSRVPSSSPSFFYFWPPPPPPPPSFLPS... | [
{
"source_db": "GTEx",
"source_id": "Brain_Caudate_basal_ganglia",
"text": "PDE10A GENE_EXPRESSED_IN_TISSUE Brain_Caudate_basal_ganglia",
"confidence": 0.369352058
}
] | {
"gene": "PDE10A",
"top_tissue": "Brain_Caudate_basal_ganglia",
"top_tpm": 11.8297
} | 0.369352 |
no_tiss_00146 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is PFN1 most highly expressed? | PFN1 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "PFN1",
"source_node_type": "GENE",
"source_node_label": "PFN1",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 1,
"edge_source_db": "GTEx",
"target_node_id": "Cell... | D | [
"A. Brain_Anterior_cingulate_cortex_BA24",
"B. Brain_Putamen_basal_ganglia",
"C. Brain_Cortex",
"D. Cells_EBV-transformed_lymphocytes"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "PFN1",
"source_db": "UniProt",
"payload": {
"accession": "P07737",
"sequence": "MAGWNAYIDNLMADGTCQDAAIVGYKDSPSVWAAVPGKTFVNITPAEVGVLVGKDRSSFYVNGLTLGGQKCSVIRDSLLQDGEFSMDLRTKSTGGAPTFNVTVTKTDKTLVLLMGKEGVHGGLINKKCYEMASH... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "PFN1 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 1
}
] | {
"gene": "PFN1",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 1612.44
} | 1 |
no_tiss_00147 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is PDE10A most highly expressed? | PDE10A GENE_EXPRESSED_IN_TISSUE Brain_Caudate_basal_ganglia | {
"steps": [
{
"hop": 1,
"source_node_id": "PDE10A",
"source_node_type": "GENE",
"source_node_label": "PDE10A",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.369352058,
"edge_source_db": "GTEx",
"target_n... | B | [
"A. Whole_Blood",
"B. Brain_Caudate_basal_ganglia",
"C. Cells_Cultured_fibroblasts",
"D. Cells_EBV-transformed_lymphocytes"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "PDE10A",
"source_db": "UniProt",
"payload": {
"accession": "Q9Y233",
"sequence": "MASLEEPLAPRPQGPLPAAGDEPGCGPGKLRPEPRLSAAGGGSAAGPGPAPEWPGRGRAERAAPPRPPLSSAGRPSPAGGPGALSARGGGCGWVAARAPLALAFSSRVPSSSPSFFYFWPPPPPPPPSFLPS... | [
{
"source_db": "GTEx",
"source_id": "Brain_Caudate_basal_ganglia",
"text": "PDE10A GENE_EXPRESSED_IN_TISSUE Brain_Caudate_basal_ganglia",
"confidence": 0.369352058
}
] | {
"gene": "PDE10A",
"top_tissue": "Brain_Caudate_basal_ganglia",
"top_tpm": 11.8297
} | 0.369352 |
no_tiss_00148 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is SOD1 most highly expressed? | SOD1 GENE_EXPRESSED_IN_TISSUE Liver | {
"steps": [
{
"hop": 1,
"source_node_id": "SOD1",
"source_node_type": "GENE",
"source_node_label": "SOD1",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.8596044894,
"edge_source_db": "GTEx",
"target_node... | B | [
"A. Skin_Not_Sun_Exposed_Suprapubic",
"B. Liver",
"C. Pancreas",
"D. Whole_Blood"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "SOD1",
"source_db": "UniProt",
"payload": {
"accession": "P00441",
"sequence": "MATKAVCVLKGDGPVQGIINFEQKESNGPVKVWGSIKGLTEGLHGFHVHEFGDNTAGCTSAGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVADVSIEDSVISLSGDHCIIGRTLVVHEKADDLGKGGNEE... | [
{
"source_db": "GTEx",
"source_id": "Liver",
"text": "SOD1 GENE_EXPRESSED_IN_TISSUE Liver",
"confidence": 0.8596044894
}
] | {
"gene": "SOD1",
"top_tissue": "Liver",
"top_tpm": 378.478
} | 0.859604 |
no_tiss_00149 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is KIF5A most highly expressed? | KIF5A GENE_EXPRESSED_IN_TISSUE Brain_Cortex | {
"steps": [
{
"hop": 1,
"source_node_id": "KIF5A",
"source_node_type": "GENE",
"source_node_label": "KIF5A",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 1,
"edge_source_db": "GTEx",
"target_node_id": "Br... | C | [
"A. Muscle_Skeletal",
"B. Liver",
"C. Brain_Cortex",
"D. Whole_Blood"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "KIF5A",
"source_db": "UniProt",
"payload": {
"accession": "Q12840",
"sequence": "MAETNNECSIKVLCRFRPLNQAEILRGDKFIPIFQGDDSVVIGGKPYVFDRVFPPNTTQEQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIARDIFNHIYSMDENLEFHIKV... | [
{
"source_db": "GTEx",
"source_id": "Brain_Cortex",
"text": "KIF5A GENE_EXPRESSED_IN_TISSUE Brain_Cortex",
"confidence": 1
}
] | {
"gene": "KIF5A",
"top_tissue": "Brain_Cortex",
"top_tpm": 1160.24
} | 1 |
no_tiss_00150 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is FBXO7 most highly expressed? | FBXO7 GENE_EXPRESSED_IN_TISSUE Whole_Blood | {
"steps": [
{
"hop": 1,
"source_node_id": "FBXO7",
"source_node_type": "GENE",
"source_node_label": "FBXO7",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.80654072,
"edge_source_db": "GTEx",
"target_node... | A | [
"A. Whole_Blood",
"B. Pancreas",
"C. Heart_Left_Ventricle",
"D. Muscle_Skeletal"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "FBXO7",
"source_db": "UniProt",
"payload": {
"accession": "Q9Y3I1",
"sequence": "MRLRVRLLKRTWPLEVPETEPTLGHLRSHLRQSLLCTWGYSSNTRFTITLNYKDPLTGDEETLASYGIVSGDLICLILQDDIPAPNIPSSTDSEHSSLQNNEQPSLATSSNQTSMQDEQPSDSFQGQAAQSGV... | [
{
"source_db": "GTEx",
"source_id": "Whole_Blood",
"text": "FBXO7 GENE_EXPRESSED_IN_TISSUE Whole_Blood",
"confidence": 0.80654072
}
] | {
"gene": "FBXO7",
"top_tissue": "Whole_Blood",
"top_tpm": 262.01
} | 0.806541 |
no_tiss_00151 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is ACO2 most highly expressed? | ACO2 GENE_EXPRESSED_IN_TISSUE Muscle_Skeletal | {
"steps": [
{
"hop": 1,
"source_node_id": "ACO2",
"source_node_type": "GENE",
"source_node_label": "ACO2",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.8121290683,
"edge_source_db": "GTEx",
"target_node... | A | [
"A. Muscle_Skeletal",
"B. Whole_Blood",
"C. Liver",
"D. Pancreas"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "ACO2",
"source_db": "UniProt",
"payload": {
"accession": "Q99798",
"sequence": "MAPYSLLVTRLQKALGVRQYHVASVLCQRAKVAMSHFEPNEYIHYDLLEKNINIVRKRLNRPLTLSEKIVYGHLDDPASQEIERGKSYLRLRPDRVAMQDATAQMAMLQFISSGLSKVAVPSTIHCDHLIEAQV... | [
{
"source_db": "GTEx",
"source_id": "Muscle_Skeletal",
"text": "ACO2 GENE_EXPRESSED_IN_TISSUE Muscle_Skeletal",
"confidence": 0.8121290683
}
] | {
"gene": "ACO2",
"top_tissue": "Muscle_Skeletal",
"top_tpm": 272.363
} | 0.812129 |
no_tiss_00152 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is APH1B most highly expressed? | APH1B GENE_EXPRESSED_IN_TISSUE Testis | {
"steps": [
{
"hop": 1,
"source_node_id": "APH1B",
"source_node_type": "GENE",
"source_node_label": "APH1B",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.6449154701,
"edge_source_db": "GTEx",
"target_no... | B | [
"A. Heart_Left_Ventricle",
"B. Testis",
"C. Pancreas",
"D. Liver"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "APH1B",
"source_db": "UniProt",
"payload": {
"accession": "Q8WW43",
"sequence": "MTAAVFFGCAFIAFGPALALYVFTIATEPLRIIFLIAGAFFWLVSLLISSLVWFMARVIIDNKDGPTQKYLLIFGAFVSVYIQEMFRFAYYKLLKKASEGLKSINPGETAPSMRLLAYVSGLGFGIMSGVFSF... | [
{
"source_db": "GTEx",
"source_id": "Testis",
"text": "APH1B GENE_EXPRESSED_IN_TISSUE Testis",
"confidence": 0.6449154701
}
] | {
"gene": "APH1B",
"top_tissue": "Testis",
"top_tpm": 85.1046
} | 0.644915 |
no_tiss_00153 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is OPTN most highly expressed? | OPTN GENE_EXPRESSED_IN_TISSUE Muscle_Skeletal | {
"steps": [
{
"hop": 1,
"source_node_id": "OPTN",
"source_node_type": "GENE",
"source_node_label": "OPTN",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.8551569045,
"edge_source_db": "GTEx",
"target_node... | A | [
"A. Muscle_Skeletal",
"B. Liver",
"C. Pancreas",
"D. Whole_Blood"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "OPTN",
"source_db": "UniProt",
"payload": {
"accession": "Q96CV9",
"sequence": "MSHQPLSCLTEKEDSPSESTGNGPPHLAHPNLDTFTPEELLQQMKELLTENHQLKEAMKLNNQAMKGRFEELSAWTEKQKEERQFFEIQSKEAKERLMALSHENEKLKEELGKLKGKSERSSEDPTDDSRLPRA... | [
{
"source_db": "GTEx",
"source_id": "Muscle_Skeletal",
"text": "OPTN GENE_EXPRESSED_IN_TISSUE Muscle_Skeletal",
"confidence": 0.8551569045
}
] | {
"gene": "OPTN",
"top_tissue": "Muscle_Skeletal",
"top_tpm": 366.995
} | 0.855157 |
no_tiss_00154 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is NEFL most highly expressed? | NEFL GENE_EXPRESSED_IN_TISSUE Brain_Frontal_Cortex_BA9 | {
"steps": [
{
"hop": 1,
"source_node_id": "NEFL",
"source_node_type": "GENE",
"source_node_label": "NEFL",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.8960678249,
"edge_source_db": "GTEx",
"target_node... | D | [
"A. Heart_Left_Ventricle",
"B. Cells_EBV-transformed_lymphocytes",
"C. Liver",
"D. Brain_Frontal_Cortex_BA9"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "NEFL",
"source_db": "UniProt",
"payload": {
"accession": "P07196",
"sequence": "MSSFSYEPYYSTSYKRRYVETPRVHISSVRSGYSTARSAYSSYSAPVSSSLSVRRSYSSSSGSLMPSLENLDLSQVAAISNDLKSIRTQEKAQLQDLNDRFASFIERVHELEQQNKVLEAELLVLRQKHSEPSR... | [
{
"source_db": "GTEx",
"source_id": "Brain_Frontal_Cortex_BA9",
"text": "NEFL GENE_EXPRESSED_IN_TISSUE Brain_Frontal_Cortex_BA9",
"confidence": 0.8960678249
}
] | {
"gene": "NEFL",
"top_tissue": "Brain_Frontal_Cortex_BA9",
"top_tpm": 487.194
} | 0.896068 |
no_tiss_00155 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is STK11 most highly expressed? | STK11 GENE_EXPRESSED_IN_TISSUE Testis | {
"steps": [
{
"hop": 1,
"source_node_id": "STK11",
"source_node_type": "GENE",
"source_node_label": "STK11",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.6937324649,
"edge_source_db": "GTEx",
"target_no... | C | [
"A. Brain_Spinal_cord_cervical_c-1",
"B. Brain_Substantia_nigra",
"C. Testis",
"D. Pancreas"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "STK11",
"source_db": "UniProt",
"payload": {
"accession": "Q15831",
"sequence": "MEVVDPQQLGMFTEGELMSVGMDTFIHRIDSTEVIYQPRRKRAKLIGKYLMGDLLGEGSYGKVKEVLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHKNVIQLVDVLYNEEKQKMYMVMEYCV... | [
{
"source_db": "GTEx",
"source_id": "Testis",
"text": "STK11 GENE_EXPRESSED_IN_TISSUE Testis",
"confidence": 0.6937324649
}
] | {
"gene": "STK11",
"top_tissue": "Testis",
"top_tpm": 119.642
} | 0.693732 |
no_tiss_00156 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is ALK most highly expressed? | ALK GENE_EXPRESSED_IN_TISSUE Pituitary | {
"steps": [
{
"hop": 1,
"source_node_id": "ALK",
"source_node_type": "GENE",
"source_node_label": "ALK",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.218719834,
"edge_source_db": "GTEx",
"target_node_id... | D | [
"A. Cells_Cultured_fibroblasts",
"B. Liver",
"C. Whole_Blood",
"D. Pituitary"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "ALK",
"source_db": "UniProt",
"payload": {
"accession": "Q9UM73",
"sequence": "MGAIGLLWLLPLLLSTAAVGSGMGTGQRAGSPAAGPPLQPREPLSYSRLQRKSLAVDFVVPSLFRVYARDLLLPPSSSELKAGRPEARGSLALDCAPLLRLLGPAPGVSWTAGSPAPAEARTLSRVLKGGSVRKL... | [
{
"source_db": "GTEx",
"source_id": "Pituitary",
"text": "ALK GENE_EXPRESSED_IN_TISSUE Pituitary",
"confidence": 0.218719834
}
] | {
"gene": "ALK",
"top_tissue": "Pituitary",
"top_tpm": 3.53163
} | 0.21872 |
no_tiss_00157 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is NRAS most highly expressed? | NRAS GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "NRAS",
"source_node_type": "GENE",
"source_node_label": "NRAS",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.6311424453,
"edge_source_db": "GTEx",
"target_node... | B | [
"A. Heart_Atrial_Appendage",
"B. Cells_EBV-transformed_lymphocytes",
"C. Muscle_Skeletal",
"D. Heart_Left_Ventricle"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "NRAS",
"source_db": "UniProt",
"payload": {
"accession": "P01111",
"sequence": "MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDLPTRTVDTKQAHELA... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "NRAS GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 0.6311424453
}
] | {
"gene": "NRAS",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 77.2891
} | 0.631142 |
no_tiss_00158 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is CSF3R most highly expressed? | CSF3R GENE_EXPRESSED_IN_TISSUE Whole_Blood | {
"steps": [
{
"hop": 1,
"source_node_id": "CSF3R",
"source_node_type": "GENE",
"source_node_label": "CSF3R",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 1,
"edge_source_db": "GTEx",
"target_node_id": "Wh... | C | [
"A. Pancreas",
"B. Cells_Cultured_fibroblasts",
"C. Whole_Blood",
"D. Cells_EBV-transformed_lymphocytes"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "CSF3R",
"source_db": "UniProt",
"payload": {
"accession": "Q99062",
"sequence": "MARLGNCSLTWAALIILLLPGSLEECGHISVSAPIVHLGDPITASCIIKQNCSHLDPEPQILWRLGAELQPGGRQQRLSDGTQESIITLPHLNHTQAFLSCCLNWGNSLQILDQVELRAGYPPAIPHNLSCLM... | [
{
"source_db": "GTEx",
"source_id": "Whole_Blood",
"text": "CSF3R GENE_EXPRESSED_IN_TISSUE Whole_Blood",
"confidence": 1
}
] | {
"gene": "CSF3R",
"top_tissue": "Whole_Blood",
"top_tpm": 2125.6
} | 1 |
no_tiss_00159 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is PALB2 most highly expressed? | PALB2 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "PALB2",
"source_node_type": "GENE",
"source_node_label": "PALB2",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.388087243,
"edge_source_db": "GTEx",
"target_nod... | A | [
"A. Cells_EBV-transformed_lymphocytes",
"B. Whole_Blood",
"C. Heart_Atrial_Appendage",
"D. Heart_Left_Ventricle"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "PALB2",
"source_db": "UniProt",
"payload": {
"accession": "Q86YC2",
"sequence": "MDEPPGKPLSCEEKEKLKEKLAFLKREYSKTLARLQRAQRAEKIKHSIKKTVEEQDCLSQQDLSPQLKHSEPKNKICVYDKLHIKTHLDEETGEKTSITLDVGPESFNPGDGPGGLPIQRTDDTQEHFPHRVS... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "PALB2 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 0.388087243
}
] | {
"gene": "PALB2",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 13.6026
} | 0.388087 |
no_tiss_00160 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is KMT2D most highly expressed? | KMT2D GENE_EXPRESSED_IN_TISSUE Uterus | {
"steps": [
{
"hop": 1,
"source_node_id": "KMT2D",
"source_node_type": "GENE",
"source_node_label": "KMT2D",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.4969024269,
"edge_source_db": "GTEx",
"target_no... | C | [
"A. Brain_Substantia_nigra",
"B. Brain_Putamen_basal_ganglia",
"C. Uterus",
"D. Brain_Amygdala"
] | [
"expression",
"protein_sequence"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "KMT2D",
"source_db": "UniProt",
"payload": {
"accession": "O14686",
"sequence": "MDSQKLAGEDKDSEPAADGPAASEDPSATESDLPNPHVGEVSVLSSGSPRLQETPQDCSGGPVRRCALCNCGEPSLHGQRELRRFELPFDWPRCPVVSPGGSPGPNEAVLPSEDLSQIGFPEGLTPAHLGEPG... | [
{
"source_db": "GTEx",
"source_id": "Uterus",
"text": "KMT2D GENE_EXPRESSED_IN_TISSUE Uterus",
"confidence": 0.4969024269
}
] | {
"gene": "KMT2D",
"top_tissue": "Uterus",
"top_tpm": 29.9687
} | 0.496902 |
no_tiss_00161 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is CD68 most highly expressed? | CD68 GENE_EXPRESSED_IN_TISSUE Spleen | {
"steps": [
{
"hop": 1,
"source_node_id": "CD68",
"source_node_type": "GENE",
"source_node_label": "CD68",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.8437118907,
"edge_source_db": "GTEx",
"target_node... | D | [
"A. Testis",
"B. Brain_Cortex",
"C. Brain_Anterior_cingulate_cortex_BA24",
"D. Spleen"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "CD68",
"source_db": "UniProt",
"payload": {
"accession": "P34810",
"sequence": "MRLAVLFSGALLGLLAAQGTGNDCPHKKSATLLPSFTVTPTVTESTGTTSHRTTKSHKTTTHRTTTTGTTSHGPTTATHNPTTTSHGNVTVHPTSNSTATSQGPSTATHSPATTSHGNATVHPTSNSTATSPGF... | [
{
"source_db": "GTEx",
"source_id": "Spleen",
"text": "CD68 GENE_EXPRESSED_IN_TISSUE Spleen",
"confidence": 0.8437118907
}
] | {
"gene": "CD68",
"top_tissue": "Spleen",
"top_tpm": 339.018
} | 0.843712 |
no_tiss_00162 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is PSMA6 most highly expressed? | PSMA6 GENE_EXPRESSED_IN_TISSUE Testis | {
"steps": [
{
"hop": 1,
"source_node_id": "PSMA6",
"source_node_type": "GENE",
"source_node_label": "PSMA6",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.834987975,
"edge_source_db": "GTEx",
"target_nod... | B | [
"A. Brain_Hippocampus",
"B. Testis",
"C. Brain_Putamen_basal_ganglia",
"D. Pancreas"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "PSMA6",
"source_db": "UniProt",
"payload": {
"accession": "P60900",
"sequence": "MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAEMRP... | [
{
"source_db": "GTEx",
"source_id": "Testis",
"text": "PSMA6 GENE_EXPRESSED_IN_TISSUE Testis",
"confidence": 0.834987975
}
] | {
"gene": "PSMA6",
"top_tissue": "Testis",
"top_tpm": 319.13
} | 0.834988 |
no_tiss_00163 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is ATM most highly expressed? | ATM GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "ATM",
"source_node_type": "GENE",
"source_node_label": "ATM",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.4475955638,
"edge_source_db": "GTEx",
"target_node_i... | D | [
"A. Heart_Left_Ventricle",
"B. Brain_Anterior_cingulate_cortex_BA24",
"C. Muscle_Skeletal",
"D. Cells_EBV-transformed_lymphocytes"
] | [
"expression",
"protein_sequence"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "ATM",
"source_db": "UniProt",
"payload": {
"accession": "Q13315",
"sequence": "MSLVLNDLLICCRQLEHDRATERKKEVEKFKRLIRDPETIKHLDRHSDSKQGKYLNWDAVFRFLQKYIQKETECLRIAKPNVSASTQASRQKKMQEISSLVKYFIKCANRRAPRLKCQELLNYIMDTVKDSSNGA... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "ATM GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 0.4475955638
}
] | {
"gene": "ATM",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 21.0283
} | 0.447596 |
no_tiss_00164 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is CD44 most highly expressed? | CD44 GENE_EXPRESSED_IN_TISSUE Skin_Not_Sun_Exposed_Suprapubic | {
"steps": [
{
"hop": 1,
"source_node_id": "CD44",
"source_node_type": "GENE",
"source_node_label": "CD44",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.7901935614,
"edge_source_db": "GTEx",
"target_node... | C | [
"A. Brain_Nucleus_accumbens_basal_ganglia",
"B. Brain_Putamen_basal_ganglia",
"C. Skin_Not_Sun_Exposed_Suprapubic",
"D. Brain_Frontal_Cortex_BA9"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "CD44",
"source_db": "UniProt",
"payload": {
"accession": "P16070",
"sequence": "MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTLPTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTD... | [
{
"source_db": "GTEx",
"source_id": "Skin_Not_Sun_Exposed_Suprapubic",
"text": "CD44 GENE_EXPRESSED_IN_TISSUE Skin_Not_Sun_Exposed_Suprapubic",
"confidence": 0.7901935614
}
] | {
"gene": "CD44",
"top_tissue": "Skin_Not_Sun_Exposed_Suprapubic",
"top_tpm": 233.922
} | 0.790194 |
no_tiss_00165 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is CD8A most highly expressed? | CD8A GENE_EXPRESSED_IN_TISSUE Spleen | {
"steps": [
{
"hop": 1,
"source_node_id": "CD8A",
"source_node_type": "GENE",
"source_node_label": "CD8A",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.6728277704,
"edge_source_db": "GTEx",
"target_node... | A | [
"A. Spleen",
"B. Cells_Cultured_fibroblasts",
"C. Cells_EBV-transformed_lymphocytes",
"D. Muscle_Skeletal"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "CD8A",
"source_db": "UniProt",
"payload": {
"accession": "P01732",
"sequence": "MALPVTALLLPLALLLHAARPSQFRVSPLDRTWNLGETVELKCQVLLSNPTSGCSWLFQPRGAAASPTFLLYLSQNKPKAAEGLDTQRFSGKRLGDTFVLTLSDFRRENEGYYFCSALSNSIMYFSHFVPVFLP... | [
{
"source_db": "GTEx",
"source_id": "Spleen",
"text": "CD8A GENE_EXPRESSED_IN_TISSUE Spleen",
"confidence": 0.6728277704
}
] | {
"gene": "CD8A",
"top_tissue": "Spleen",
"top_tpm": 103.418
} | 0.672828 |
no_tiss_00166 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is APP most highly expressed? | APP GENE_EXPRESSED_IN_TISSUE Brain_Frontal_Cortex_BA9 | {
"steps": [
{
"hop": 1,
"source_node_id": "APP",
"source_node_type": "GENE",
"source_node_label": "APP",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.9164822217,
"edge_source_db": "GTEx",
"target_node_i... | C | [
"A. Whole_Blood",
"B. Muscle_Skeletal",
"C. Brain_Frontal_Cortex_BA9",
"D. Cells_EBV-transformed_lymphocytes"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "APP",
"source_db": "UniProt",
"payload": {
"accession": "P05067",
"sequence": "MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKF... | [
{
"source_db": "GTEx",
"source_id": "Brain_Frontal_Cortex_BA9",
"text": "APP GENE_EXPRESSED_IN_TISSUE Brain_Frontal_Cortex_BA9",
"confidence": 0.9164822217
}
] | {
"gene": "APP",
"top_tissue": "Brain_Frontal_Cortex_BA9",
"top_tpm": 561.14
} | 0.916482 |
no_tiss_00167 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is PFN1 most highly expressed? | PFN1 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "PFN1",
"source_node_type": "GENE",
"source_node_label": "PFN1",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 1,
"edge_source_db": "GTEx",
"target_node_id": "Cell... | B | [
"A. Brain_Putamen_basal_ganglia",
"B. Cells_EBV-transformed_lymphocytes",
"C. Brain_Cortex",
"D. Brain_Anterior_cingulate_cortex_BA24"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "PFN1",
"source_db": "UniProt",
"payload": {
"accession": "P07737",
"sequence": "MAGWNAYIDNLMADGTCQDAAIVGYKDSPSVWAAVPGKTFVNITPAEVGVLVGKDRSSFYVNGLTLGGQKCSVIRDSLLQDGEFSMDLRTKSTGGAPTFNVTVTKTDKTLVLLMGKEGVHGGLINKKCYEMASH... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "PFN1 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 1
}
] | {
"gene": "PFN1",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 1612.44
} | 1 |
no_tiss_00168 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is CDKN1A most highly expressed? | CDKN1A GENE_EXPRESSED_IN_TISSUE Artery_Aorta | {
"steps": [
{
"hop": 1,
"source_node_id": "CDKN1A",
"source_node_type": "GENE",
"source_node_label": "CDKN1A",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.8738858036,
"edge_source_db": "GTEx",
"target_... | B | [
"A. Brain_Cerebellar_Hemisphere",
"B. Artery_Aorta",
"C. Brain_Putamen_basal_ganglia",
"D. Brain_Cerebellum"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "CDKN1A",
"source_db": "UniProt",
"payload": {
"accession": "P38936",
"sequence": "MSEPAGDVRQNPCGSKACRRLFGPVDSEQLSRDCDALMAGCIQEARERWNFDFVTETPLEGDFAWERVRGLGLPKLYLPTGPRRGRDELGGGRRPGTSPALLQGTAEEDHVDLSLSCTLVPRSGEQAEGSPG... | [
{
"source_db": "GTEx",
"source_id": "Artery_Aorta",
"text": "CDKN1A GENE_EXPRESSED_IN_TISSUE Artery_Aorta",
"confidence": 0.8738858036
}
] | {
"gene": "CDKN1A",
"top_tissue": "Artery_Aorta",
"top_tpm": 417.829
} | 0.873886 |
no_tiss_00169 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is BCHE most highly expressed? | BCHE GENE_EXPRESSED_IN_TISSUE Fallopian_Tube | {
"steps": [
{
"hop": 1,
"source_node_id": "BCHE",
"source_node_type": "GENE",
"source_node_label": "BCHE",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.5397511603,
"edge_source_db": "GTEx",
"target_node... | A | [
"A. Fallopian_Tube",
"B. Pancreas",
"C. Cells_EBV-transformed_lymphocytes",
"D. Whole_Blood"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "BCHE",
"source_db": "UniProt",
"payload": {
"accession": "P06276",
"sequence": "MHSKVTIICIRFLFWFLLLCMLIGKSHTEDDIIIATKNGKVRGMNLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKN... | [
{
"source_db": "GTEx",
"source_id": "Fallopian_Tube",
"text": "BCHE GENE_EXPRESSED_IN_TISSUE Fallopian_Tube",
"confidence": 0.5397511603
}
] | {
"gene": "BCHE",
"top_tissue": "Fallopian_Tube",
"top_tpm": 40.6378
} | 0.539751 |
no_tiss_00170 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is BAX most highly expressed? | BAX GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "BAX",
"source_node_type": "GENE",
"source_node_label": "BAX",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.77659884,
"edge_source_db": "GTEx",
"target_node_id"... | C | [
"A. Muscle_Skeletal",
"B. Brain_Putamen_basal_ganglia",
"C. Cells_EBV-transformed_lymphocytes",
"D. Heart_Left_Ventricle"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "BAX",
"source_db": "UniProt",
"payload": {
"accession": "Q07812",
"sequence": "MDGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKLSECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKLVLKALCTKVPELIRT... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "BAX GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 0.77659884
}
] | {
"gene": "BAX",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 212.862
} | 0.776599 |
no_tiss_00171 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is CSF1R most highly expressed? | CSF1R GENE_EXPRESSED_IN_TISSUE Spleen | {
"steps": [
{
"hop": 1,
"source_node_id": "CSF1R",
"source_node_type": "GENE",
"source_node_label": "CSF1R",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.7724875881,
"edge_source_db": "GTEx",
"target_no... | B | [
"A. Muscle_Skeletal",
"B. Spleen",
"C. Cells_EBV-transformed_lymphocytes",
"D. Cells_Cultured_fibroblasts"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "CSF1R",
"source_db": "UniProt",
"payload": {
"accession": "P07333",
"sequence": "MGPGVLLLLLVATAWHGQGIPVIEPSVPELVVKPGATVTLRCVGNGSVEWDGPPSPHWTLYSDGSSSILSTNNATFQNTGTYRCTEPGDPLGGSAAIHLYVKDPARPWNVLAQEVVVFEDQDALLPCLLTDPV... | [
{
"source_db": "GTEx",
"source_id": "Spleen",
"text": "CSF1R GENE_EXPRESSED_IN_TISSUE Spleen",
"confidence": 0.7724875881
}
] | {
"gene": "CSF1R",
"top_tissue": "Spleen",
"top_tpm": 206.873
} | 0.772488 |
no_tiss_00172 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is BRIP1 most highly expressed? | BRIP1 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "BRIP1",
"source_node_type": "GENE",
"source_node_label": "BRIP1",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.3370133372,
"edge_source_db": "GTEx",
"target_no... | D | [
"A. Heart_Left_Ventricle",
"B. Heart_Atrial_Appendage",
"C. Muscle_Skeletal",
"D. Cells_EBV-transformed_lymphocytes"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "BRIP1",
"source_db": "UniProt",
"payload": {
"accession": "Q9BX63",
"sequence": "MSSMWSEYTIGGVKIYFPYKAYPSQLAMMNSILRGLNSKQHCLLESPTGSGKSLALLCSALAWQQSLSGKPADEGVSEKAEVQLSCCCACHSKDFTNNDMNQGTSRHFNYPSTPPSERNGTSSTCQDSPEKTT... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "BRIP1 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 0.3370133372
}
] | {
"gene": "BRIP1",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 9.26092
} | 0.337013 |
no_tiss_00173 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is KRAS most highly expressed? | KRAS GENE_EXPRESSED_IN_TISSUE Nerve_Tibial | {
"steps": [
{
"hop": 1,
"source_node_id": "KRAS",
"source_node_type": "GENE",
"source_node_label": "KRAS",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.5004468095,
"edge_source_db": "GTEx",
"target_node... | A | [
"A. Nerve_Tibial",
"B. Heart_Left_Ventricle",
"C. Pancreas",
"D. Muscle_Skeletal"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "KRAS",
"source_db": "UniProt",
"payload": {
"accession": "P01116",
"sequence": "MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLA... | [
{
"source_db": "GTEx",
"source_id": "Nerve_Tibial",
"text": "KRAS GENE_EXPRESSED_IN_TISSUE Nerve_Tibial",
"confidence": 0.5004468095
}
] | {
"gene": "KRAS",
"top_tissue": "Nerve_Tibial",
"top_tpm": 30.7364
} | 0.500447 |
no_tiss_00174 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is AKAP11 most highly expressed? | AKAP11 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "AKAP11",
"source_node_type": "GENE",
"source_node_label": "AKAP11",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.55130567,
"edge_source_db": "GTEx",
"target_no... | D | [
"A. Liver",
"B. Whole_Blood",
"C. Heart_Left_Ventricle",
"D. Cells_EBV-transformed_lymphocytes"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "AKAP11",
"source_db": "UniProt",
"payload": {
"accession": "Q9UKA4",
"sequence": "MATFRNNHMKTKASVRKSFSEDVFQSVKSLLQSQKELCSVTAEDCLQQDEHANLTEVTFLGFNEETDAAHIQDLAAVSLELPDILNSLHFCSLNENEIICMKNINKPLDISSDPLNQSHPSGMLCVMRVSPT... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "AKAP11 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 0.55130567
}
] | {
"gene": "AKAP11",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 44.0979
} | 0.551306 |
no_tiss_00175 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is CAMLG most highly expressed? | CAMLG GENE_EXPRESSED_IN_TISSUE Ovary | {
"steps": [
{
"hop": 1,
"source_node_id": "CAMLG",
"source_node_type": "GENE",
"source_node_label": "CAMLG",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.6675824836,
"edge_source_db": "GTEx",
"target_no... | A | [
"A. Ovary",
"B. Whole_Blood",
"C. Liver",
"D. Heart_Left_Ventricle"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "CAMLG",
"source_db": "UniProt",
"payload": {
"accession": "P49069",
"sequence": "MESMAVATDGGERPGVPAGSGLSASQRRAELRRRKLLMNSEQRINRIMGFHRPGSGAEEESQTKSKQQDSDKLNSLSVPSVSKRVVLGDSVSTGTTDQQGGVAEVKGTQLGDKLDSFIKPPECSSDVNLELRQ... | [
{
"source_db": "GTEx",
"source_id": "Ovary",
"text": "CAMLG GENE_EXPRESSED_IN_TISSUE Ovary",
"confidence": 0.6675824836
}
] | {
"gene": "CAMLG",
"top_tissue": "Ovary",
"top_tpm": 99.7018
} | 0.667582 |
no_tiss_00176 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is CHCHD10 most highly expressed? | CHCHD10 GENE_EXPRESSED_IN_TISSUE Heart_Left_Ventricle | {
"steps": [
{
"hop": 1,
"source_node_id": "CHCHD10",
"source_node_type": "GENE",
"source_node_label": "CHCHD10",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.7988963175,
"edge_source_db": "GTEx",
"targe... | C | [
"A. Uterus",
"B. Ovary",
"C. Heart_Left_Ventricle",
"D. Whole_Blood"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "CHCHD10",
"source_db": "UniProt",
"payload": {
"accession": "Q8WYQ3",
"sequence": "MPRGSRSAASRPASRPAAPSAHPPAHPPPSAAAPAPAPSGQPGLMAQMATTAAGVAVGSAVGHVMGSALTGAFSGGSSEPSQPAVQQAPTPAAPQPLQMGPCAYEIRQFLDCSTTQSDLSLCEGFSEALKQ... | [
{
"source_db": "GTEx",
"source_id": "Heart_Left_Ventricle",
"text": "CHCHD10 GENE_EXPRESSED_IN_TISSUE Heart_Left_Ventricle",
"confidence": 0.7988963175
}
] | {
"gene": "CHCHD10",
"top_tissue": "Heart_Left_Ventricle",
"top_tpm": 248.48
} | 0.798896 |
no_tiss_00177 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is CHCHD10 most highly expressed? | CHCHD10 GENE_EXPRESSED_IN_TISSUE Heart_Left_Ventricle | {
"steps": [
{
"hop": 1,
"source_node_id": "CHCHD10",
"source_node_type": "GENE",
"source_node_label": "CHCHD10",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.7988963175,
"edge_source_db": "GTEx",
"targe... | C | [
"A. Ovary",
"B. Uterus",
"C. Heart_Left_Ventricle",
"D. Whole_Blood"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "CHCHD10",
"source_db": "UniProt",
"payload": {
"accession": "Q8WYQ3",
"sequence": "MPRGSRSAASRPASRPAAPSAHPPAHPPPSAAAPAPAPSGQPGLMAQMATTAAGVAVGSAVGHVMGSALTGAFSGGSSEPSQPAVQQAPTPAAPQPLQMGPCAYEIRQFLDCSTTQSDLSLCEGFSEALKQ... | [
{
"source_db": "GTEx",
"source_id": "Heart_Left_Ventricle",
"text": "CHCHD10 GENE_EXPRESSED_IN_TISSUE Heart_Left_Ventricle",
"confidence": 0.7988963175
}
] | {
"gene": "CHCHD10",
"top_tissue": "Heart_Left_Ventricle",
"top_tpm": 248.48
} | 0.798896 |
no_tiss_00178 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is CHEK2 most highly expressed? | CHEK2 GENE_EXPRESSED_IN_TISSUE Nerve_Tibial | {
"steps": [
{
"hop": 1,
"source_node_id": "CHEK2",
"source_node_type": "GENE",
"source_node_label": "CHEK2",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.3977285804,
"edge_source_db": "GTEx",
"target_no... | D | [
"A. Brain_Cerebellum",
"B. Muscle_Skeletal",
"C. Brain_Cerebellar_Hemisphere",
"D. Nerve_Tibial"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "CHEK2",
"source_db": "UniProt",
"payload": {
"accession": "O96017",
"sequence": "MSRESDVEAQQSHGSSACSQPHGSVTQSQGSSSQSQGISSSSTSTMPNSSQSSHSSSGTLSSLETVSTQELYSIPEDQEPEDQEPEEPTPAPWARLWALQDGFANLECVNDNYWFGRDKSCEYCFDEPLLKRT... | [
{
"source_db": "GTEx",
"source_id": "Nerve_Tibial",
"text": "CHEK2 GENE_EXPRESSED_IN_TISSUE Nerve_Tibial",
"confidence": 0.3977285804
}
] | {
"gene": "CHEK2",
"top_tissue": "Nerve_Tibial",
"top_tpm": 14.6084
} | 0.397729 |
no_tiss_00179 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is CDK6 most highly expressed? | CDK6 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "CDK6",
"source_node_type": "GENE",
"source_node_label": "CDK6",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.507407993,
"edge_source_db": "GTEx",
"target_node_... | D | [
"A. Muscle_Skeletal",
"B. Whole_Blood",
"C. Brain_Anterior_cingulate_cortex_BA24",
"D. Cells_EBV-transformed_lymphocytes"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "CDK6",
"source_db": "UniProt",
"payload": {
"accession": "Q00534",
"sequence": "MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLD... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "CDK6 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 0.507407993
}
] | {
"gene": "CDK6",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 32.3
} | 0.507408 |
no_tiss_00180 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is BRCA1 most highly expressed? | BRCA1 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "BRCA1",
"source_node_type": "GENE",
"source_node_label": "BRCA1",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.4390708163,
"edge_source_db": "GTEx",
"target_no... | B | [
"A. Kidney_Medulla",
"B. Cells_EBV-transformed_lymphocytes",
"C. Pancreas",
"D. Kidney_Cortex"
] | [
"expression",
"intercell_role",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "BRCA1",
"source_db": "UniProt",
"payload": {
"accession": "P38398",
"sequence": "MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKDEVSIIQSMGYRNR... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "BRCA1 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 0.4390708163
}
] | {
"gene": "BRCA1",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 19.7684
} | 0.439071 |
no_tiss_00181 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is BRCA1 most highly expressed? | BRCA1 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "BRCA1",
"source_node_type": "GENE",
"source_node_label": "BRCA1",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.4390708163,
"edge_source_db": "GTEx",
"target_no... | C | [
"A. Kidney_Medulla",
"B. Kidney_Cortex",
"C. Cells_EBV-transformed_lymphocytes",
"D. Pancreas"
] | [
"expression",
"intercell_role",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "BRCA1",
"source_db": "UniProt",
"payload": {
"accession": "P38398",
"sequence": "MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKDEVSIIQSMGYRNR... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "BRCA1 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 0.4390708163
}
] | {
"gene": "BRCA1",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 19.7684
} | 0.439071 |
no_tiss_00182 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is PPP1R1B most highly expressed? | PPP1R1B GENE_EXPRESSED_IN_TISSUE Brain_Caudate_basal_ganglia | {
"steps": [
{
"hop": 1,
"source_node_id": "PPP1R1B",
"source_node_type": "GENE",
"source_node_label": "PPP1R1B",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 1,
"edge_source_db": "GTEx",
"target_node_id":... | B | [
"A. Liver",
"B. Brain_Caudate_basal_ganglia",
"C. Cells_Cultured_fibroblasts",
"D. Spleen"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "PPP1R1B",
"source_db": "UniProt",
"payload": {
"accession": "Q9UD71",
"sequence": "MDPKDRKKIQFSVPAPPSQLDPRQVEMIRRRRPTPAMLFRLSEHSSPEEEASPHQRASGEGHHLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNLNENQASEEEDELGELRELGYPREEDEEEEEDDEEE... | [
{
"source_db": "GTEx",
"source_id": "Brain_Caudate_basal_ganglia",
"text": "PPP1R1B GENE_EXPRESSED_IN_TISSUE Brain_Caudate_basal_ganglia",
"confidence": 1
}
] | {
"gene": "PPP1R1B",
"top_tissue": "Brain_Caudate_basal_ganglia",
"top_tpm": 1254.74
} | 1 |
no_tiss_00183 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is ACKR3 most highly expressed? | ACKR3 GENE_EXPRESSED_IN_TISSUE Artery_Tibial | {
"steps": [
{
"hop": 1,
"source_node_id": "ACKR3",
"source_node_type": "GENE",
"source_node_label": "ACKR3",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.7479222763,
"edge_source_db": "GTEx",
"target_no... | D | [
"A. Brain_Cerebellar_Hemisphere",
"B. Adrenal_Gland",
"C. Whole_Blood",
"D. Artery_Tibial"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "ACKR3",
"source_db": "UniProt",
"payload": {
"accession": "P25106",
"sequence": "MDLHLFDYSEPGNFSDISWPCNSSDCIVVDTVMCPNMPNKSVLLYTLSFIYIFIFVIGMIANSVVVWVNIQAKTTGYDTHCYILNLAIADLWVVLTIPVWVVSLVQHNQWPMGELTCKVTHLIFSINLFGSIF... | [
{
"source_db": "GTEx",
"source_id": "Artery_Tibial",
"text": "ACKR3 GENE_EXPRESSED_IN_TISSUE Artery_Tibial",
"confidence": 0.7479222763
}
] | {
"gene": "ACKR3",
"top_tissue": "Artery_Tibial",
"top_tpm": 174.425
} | 0.747922 |
no_tiss_00184 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is MAPT most highly expressed? | MAPT GENE_EXPRESSED_IN_TISSUE Brain_Cerebellum | {
"steps": [
{
"hop": 1,
"source_node_id": "MAPT",
"source_node_type": "GENE",
"source_node_label": "MAPT",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.7833071913,
"edge_source_db": "GTEx",
"target_node... | D | [
"A. Whole_Blood",
"B. Cells_EBV-transformed_lymphocytes",
"C. Liver",
"D. Brain_Cerebellum"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "MAPT",
"source_db": "UniProt",
"payload": {
"accession": "P10636",
"sequence": "MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQE... | [
{
"source_db": "GTEx",
"source_id": "Brain_Cerebellum",
"text": "MAPT GENE_EXPRESSED_IN_TISSUE Brain_Cerebellum",
"confidence": 0.7833071913
}
] | {
"gene": "MAPT",
"top_tissue": "Brain_Cerebellum",
"top_tpm": 223.007
} | 0.783307 |
no_tiss_00185 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is FGFR1 most highly expressed? | FGFR1 GENE_EXPRESSED_IN_TISSUE Artery_Aorta | {
"steps": [
{
"hop": 1,
"source_node_id": "FGFR1",
"source_node_type": "GENE",
"source_node_label": "FGFR1",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.7211640465,
"edge_source_db": "GTEx",
"target_no... | B | [
"A. Whole_Blood",
"B. Artery_Aorta",
"C. Cells_EBV-transformed_lymphocytes",
"D. Liver"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "FGFR1",
"source_db": "UniProt",
"payload": {
"accession": "P11362",
"sequence": "MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDD... | [
{
"source_db": "GTEx",
"source_id": "Artery_Aorta",
"text": "FGFR1 GENE_EXPRESSED_IN_TISSUE Artery_Aorta",
"confidence": 0.7211640465
}
] | {
"gene": "FGFR1",
"top_tissue": "Artery_Aorta",
"top_tpm": 144.816
} | 0.721164 |
no_tiss_00186 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is ATP6V1C1 most highly expressed? | ATP6V1C1 GENE_EXPRESSED_IN_TISSUE Brain_Frontal_Cortex_BA9 | {
"steps": [
{
"hop": 1,
"source_node_id": "ATP6V1C1",
"source_node_type": "GENE",
"source_node_label": "ATP6V1C1",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.6178829732,
"edge_source_db": "GTEx",
"tar... | B | [
"A. Muscle_Skeletal",
"B. Brain_Frontal_Cortex_BA9",
"C. Heart_Left_Ventricle",
"D. Pancreas"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "ATP6V1C1",
"source_db": "UniProt",
"payload": {
"accession": "P21283",
"sequence": "MTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGVVKKVAQYMADVLEDSKDKVQENLLANGVDLVTYITRFQWDMAKYPIKQSLKNISEIIAKGVT... | [
{
"source_db": "GTEx",
"source_id": "Brain_Frontal_Cortex_BA9",
"text": "ATP6V1C1 GENE_EXPRESSED_IN_TISSUE Brain_Frontal_Cortex_BA9",
"confidence": 0.6178829732
}
] | {
"gene": "ATP6V1C1",
"top_tissue": "Brain_Frontal_Cortex_BA9",
"top_tpm": 70.436
} | 0.617883 |
no_tiss_00187 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is CDK6 most highly expressed? | CDK6 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "CDK6",
"source_node_type": "GENE",
"source_node_label": "CDK6",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.507407993,
"edge_source_db": "GTEx",
"target_node_... | D | [
"A. Muscle_Skeletal",
"B. Whole_Blood",
"C. Brain_Anterior_cingulate_cortex_BA24",
"D. Cells_EBV-transformed_lymphocytes"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "CDK6",
"source_db": "UniProt",
"payload": {
"accession": "Q00534",
"sequence": "MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLD... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "CDK6 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 0.507407993
}
] | {
"gene": "CDK6",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 32.3
} | 0.507408 |
no_tiss_00188 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is TUBA4A most highly expressed? | TUBA4A GENE_EXPRESSED_IN_TISSUE Whole_Blood | {
"steps": [
{
"hop": 1,
"source_node_id": "TUBA4A",
"source_node_type": "GENE",
"source_node_label": "TUBA4A",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.793829537,
"edge_source_db": "GTEx",
"target_n... | C | [
"A. Pancreas",
"B. Cervix_Endocervix",
"C. Whole_Blood",
"D. Cervix_Ectocervix"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "TUBA4A",
"source_db": "UniProt",
"payload": {
"accession": "P68366",
"sequence": "MRECISVHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFTTFFCETGAGKHVPRAVFVDLEPTVIDEIRNGPYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDPVLDRIRKLSDQCTGL... | [
{
"source_db": "GTEx",
"source_id": "Whole_Blood",
"text": "TUBA4A GENE_EXPRESSED_IN_TISSUE Whole_Blood",
"confidence": 0.793829537
}
] | {
"gene": "TUBA4A",
"top_tissue": "Whole_Blood",
"top_tpm": 239.898
} | 0.79383 |
no_tiss_00189 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is ACKR3 most highly expressed? | ACKR3 GENE_EXPRESSED_IN_TISSUE Artery_Tibial | {
"steps": [
{
"hop": 1,
"source_node_id": "ACKR3",
"source_node_type": "GENE",
"source_node_label": "ACKR3",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.7479222763,
"edge_source_db": "GTEx",
"target_no... | A | [
"A. Artery_Tibial",
"B. Brain_Cerebellar_Hemisphere",
"C. Adrenal_Gland",
"D. Whole_Blood"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "ACKR3",
"source_db": "UniProt",
"payload": {
"accession": "P25106",
"sequence": "MDLHLFDYSEPGNFSDISWPCNSSDCIVVDTVMCPNMPNKSVLLYTLSFIYIFIFVIGMIANSVVVWVNIQAKTTGYDTHCYILNLAIADLWVVLTIPVWVVSLVQHNQWPMGELTCKVTHLIFSINLFGSIF... | [
{
"source_db": "GTEx",
"source_id": "Artery_Tibial",
"text": "ACKR3 GENE_EXPRESSED_IN_TISSUE Artery_Tibial",
"confidence": 0.7479222763
}
] | {
"gene": "ACKR3",
"top_tissue": "Artery_Tibial",
"top_tpm": 174.425
} | 0.747922 |
no_tiss_00190 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is CDX2 most highly expressed? | CDX2 GENE_EXPRESSED_IN_TISSUE Colon_Transverse | {
"steps": [
{
"hop": 1,
"source_node_id": "CDX2",
"source_node_type": "GENE",
"source_node_label": "CDX2",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.5923297116,
"edge_source_db": "GTEx",
"target_node... | D | [
"A. Uterus",
"B. Vagina",
"C. Whole_Blood",
"D. Colon_Transverse"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "CDX2",
"source_db": "UniProt",
"payload": {
"accession": "Q99626",
"sequence": "MYVSYLLDKDVSMYPSSVRHSGGLNLAPQNFVSPPQYPDYGGYHVAAAAAAAANLDSAQSPGPSWPAAYGAPLREDWNGYAPGGAAAAANAVAHGLNGGSPAAAMGYSSPADYHPHHHPHHHPHHPAAAPSCAS... | [
{
"source_db": "GTEx",
"source_id": "Colon_Transverse",
"text": "CDX2 GENE_EXPRESSED_IN_TISSUE Colon_Transverse",
"confidence": 0.5923297116
}
] | {
"gene": "CDX2",
"top_tissue": "Colon_Transverse",
"top_tpm": 58.8751
} | 0.59233 |
no_tiss_00191 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is KMT2C most highly expressed? | KMT2C GENE_EXPRESSED_IN_TISSUE Brain_Cerebellum | {
"steps": [
{
"hop": 1,
"source_node_id": "KMT2C",
"source_node_type": "GENE",
"source_node_label": "KMT2C",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.4805797778,
"edge_source_db": "GTEx",
"target_no... | C | [
"A. Heart_Left_Ventricle",
"B. Kidney_Cortex",
"C. Brain_Cerebellum",
"D. Whole_Blood"
] | [
"expression",
"protein_sequence"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "KMT2C",
"source_db": "UniProt",
"payload": {
"accession": "Q8NEZ4",
"sequence": "MSSEEDKSVEQPQPPPPPPEEPGAPAPSPAAADKRPRGRPRKDGASPFQRARKKPRSRGKTAVEDEDSMDGLETTETETIVETEIKEQSAEEDAEAEVDNSKQLIPTLQRSVSEESANSLVSVGVEAKISEQL... | [
{
"source_db": "GTEx",
"source_id": "Brain_Cerebellum",
"text": "KMT2C GENE_EXPRESSED_IN_TISSUE Brain_Cerebellum",
"confidence": 0.4805797778
}
] | {
"gene": "KMT2C",
"top_tissue": "Brain_Cerebellum",
"top_tpm": 26.6661
} | 0.48058 |
no_tiss_00192 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is BARD1 most highly expressed? | BARD1 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "BARD1",
"source_node_type": "GENE",
"source_node_label": "BARD1",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.420936374,
"edge_source_db": "GTEx",
"target_nod... | B | [
"A. Liver",
"B. Cells_EBV-transformed_lymphocytes",
"C. Brain_Cerebellum",
"D. Brain_Cerebellar_Hemisphere"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "BARD1",
"source_db": "UniProt",
"payload": {
"accession": "Q99728",
"sequence": "MPDNRQPRNRQPRIRSGNEPRSAPAMEPDGRGAWAHSRAALDRLEKLLRCSRCTNILREPVCLGGCEHIFCSNCVSDCIGTGCPVCYTPAWIQDLKINRQLDSMIQLCSKLRNLLHDNELSDLKEDKPRKSLF... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "BARD1 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 0.420936374
}
] | {
"gene": "BARD1",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 17.3228
} | 0.420936 |
no_tiss_00193 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is ACVR1 most highly expressed? | ACVR1 GENE_EXPRESSED_IN_TISSUE Cells_Cultured_fibroblasts | {
"steps": [
{
"hop": 1,
"source_node_id": "ACVR1",
"source_node_type": "GENE",
"source_node_label": "ACVR1",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.5481918922,
"edge_source_db": "GTEx",
"target_no... | C | [
"A. Cells_EBV-transformed_lymphocytes",
"B. Whole_Blood",
"C. Cells_Cultured_fibroblasts",
"D. Pancreas"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "ACVR1",
"source_db": "UniProt",
"payload": {
"accession": "Q04771",
"sequence": "MVDGVMILPVLIMIALPSPSMEDEKPKVNPKLYMCVCEGLSCGNEDHCEGQQCFSSLSINDGFHVYQKGCFQVYEQGKMTCKTPPSPGQAVECCQGDWCNRNITAQLPTKGKSFPGTQNFHLEVGLIILSVVF... | [
{
"source_db": "GTEx",
"source_id": "Cells_Cultured_fibroblasts",
"text": "ACVR1 GENE_EXPRESSED_IN_TISSUE Cells_Cultured_fibroblasts",
"confidence": 0.5481918922
}
] | {
"gene": "ACVR1",
"top_tissue": "Cells_Cultured_fibroblasts",
"top_tpm": 43.1381
} | 0.548192 |
no_tiss_00194 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is APH1B most highly expressed? | APH1B GENE_EXPRESSED_IN_TISSUE Testis | {
"steps": [
{
"hop": 1,
"source_node_id": "APH1B",
"source_node_type": "GENE",
"source_node_label": "APH1B",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.6449154701,
"edge_source_db": "GTEx",
"target_no... | B | [
"A. Heart_Left_Ventricle",
"B. Testis",
"C. Liver",
"D. Pancreas"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "APH1B",
"source_db": "UniProt",
"payload": {
"accession": "Q8WW43",
"sequence": "MTAAVFFGCAFIAFGPALALYVFTIATEPLRIIFLIAGAFFWLVSLLISSLVWFMARVIIDNKDGPTQKYLLIFGAFVSVYIQEMFRFAYYKLLKKASEGLKSINPGETAPSMRLLAYVSGLGFGIMSGVFSF... | [
{
"source_db": "GTEx",
"source_id": "Testis",
"text": "APH1B GENE_EXPRESSED_IN_TISSUE Testis",
"confidence": 0.6449154701
}
] | {
"gene": "APH1B",
"top_tissue": "Testis",
"top_tpm": 85.1046
} | 0.644915 |
no_tiss_00195 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is PPP2R1B most highly expressed? | PPP2R1B GENE_EXPRESSED_IN_TISSUE Liver | {
"steps": [
{
"hop": 1,
"source_node_id": "PPP2R1B",
"source_node_type": "GENE",
"source_node_label": "PPP2R1B",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.6105899062,
"edge_source_db": "GTEx",
"targe... | B | [
"A. Heart_Left_Ventricle",
"B. Liver",
"C. Heart_Atrial_Appendage",
"D. Whole_Blood"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "PPP2R1B",
"source_db": "UniProt",
"payload": {
"accession": "P30154",
"sequence": "MAGASELGTGPGAAGGDGDDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIYDEDEVLLALAEQLGNFTGLVGGPDFAHCLLPPLENLATVEETVVRDKAVESLRQISQEH... | [
{
"source_db": "GTEx",
"source_id": "Liver",
"text": "PPP2R1B GENE_EXPRESSED_IN_TISSUE Liver",
"confidence": 0.6105899062
}
] | {
"gene": "PPP2R1B",
"top_tissue": "Liver",
"top_tpm": 66.9258
} | 0.61059 |
no_tiss_00196 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is BAX most highly expressed? | BAX GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "BAX",
"source_node_type": "GENE",
"source_node_label": "BAX",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.77659884,
"edge_source_db": "GTEx",
"target_node_id"... | A | [
"A. Cells_EBV-transformed_lymphocytes",
"B. Heart_Left_Ventricle",
"C. Muscle_Skeletal",
"D. Brain_Putamen_basal_ganglia"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "BAX",
"source_db": "UniProt",
"payload": {
"accession": "Q07812",
"sequence": "MDGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKLSECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKLVLKALCTKVPELIRT... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "BAX GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 0.77659884
}
] | {
"gene": "BAX",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 212.862
} | 0.776599 |
no_tiss_00197 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is EGFR most highly expressed? | EGFR GENE_EXPRESSED_IN_TISSUE Skin_Sun_Exposed_Lower_leg | {
"steps": [
{
"hop": 1,
"source_node_id": "EGFR",
"source_node_type": "GENE",
"source_node_label": "EGFR",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.6330677212,
"edge_source_db": "GTEx",
"target_node... | D | [
"A. Whole_Blood",
"B. Brain_Spinal_cord_cervical_c-1",
"C. Cells_EBV-transformed_lymphocytes",
"D. Skin_Sun_Exposed_Lower_leg"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "EGFR",
"source_db": "UniProt",
"payload": {
"accession": "P00533",
"sequence": "MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKE... | [
{
"source_db": "GTEx",
"source_id": "Skin_Sun_Exposed_Lower_leg",
"text": "EGFR GENE_EXPRESSED_IN_TISSUE Skin_Sun_Exposed_Lower_leg",
"confidence": 0.6330677212
}
] | {
"gene": "EGFR",
"top_tissue": "Skin_Sun_Exposed_Lower_leg",
"top_tpm": 78.3374
} | 0.633068 |
no_tiss_00198 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is BNIP3 most highly expressed? | BNIP3 GENE_EXPRESSED_IN_TISSUE Pancreas | {
"steps": [
{
"hop": 1,
"source_node_id": "BNIP3",
"source_node_type": "GENE",
"source_node_label": "BNIP3",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.6806024446,
"edge_source_db": "GTEx",
"target_no... | C | [
"A. Small_Intestine_Terminal_Ileum",
"B. Whole_Blood",
"C. Pancreas",
"D. Colon_Transverse"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "BNIP3",
"source_db": "UniProt",
"payload": {
"accession": "Q12983",
"sequence": "MSQNGAPGMQEESLQGSWVELHFSNNGNGGSVPASVSIYNGDMEKILLDAQHESGRSSSKSSHCDSPPRSQTPQDTNRASETDTHSIGEKNSSQSEEDDIERRKEVESILKKNSDWIWDWSSRPENIPPKEFL... | [
{
"source_db": "GTEx",
"source_id": "Pancreas",
"text": "BNIP3 GENE_EXPRESSED_IN_TISSUE Pancreas",
"confidence": 0.6806024446
}
] | {
"gene": "BNIP3",
"top_tissue": "Pancreas",
"top_tpm": 109.18
} | 0.680602 |
no_tiss_00199 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is AURKA most highly expressed? | AURKA GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "AURKA",
"source_node_type": "GENE",
"source_node_label": "AURKA",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.5728063643,
"edge_source_db": "GTEx",
"target_no... | C | [
"A. Brain_Hippocampus",
"B. Pancreas",
"C. Cells_EBV-transformed_lymphocytes",
"D. Brain_Amygdala"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "AURKA",
"source_db": "UniProt",
"payload": {
"accession": "O14965",
"sequence": "MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQAQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKNEESKKRQWALEDF... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "AURKA GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 0.5728063643
}
] | {
"gene": "AURKA",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 51.32
} | 0.572806 |
no_tiss_00200 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is STK11 most highly expressed? | STK11 GENE_EXPRESSED_IN_TISSUE Testis | {
"steps": [
{
"hop": 1,
"source_node_id": "STK11",
"source_node_type": "GENE",
"source_node_label": "STK11",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.6937324649,
"edge_source_db": "GTEx",
"target_no... | C | [
"A. Brain_Substantia_nigra",
"B. Brain_Spinal_cord_cervical_c-1",
"C. Testis",
"D. Pancreas"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "STK11",
"source_db": "UniProt",
"payload": {
"accession": "Q15831",
"sequence": "MEVVDPQQLGMFTEGELMSVGMDTFIHRIDSTEVIYQPRRKRAKLIGKYLMGDLLGEGSYGKVKEVLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHKNVIQLVDVLYNEEKQKMYMVMEYCV... | [
{
"source_db": "GTEx",
"source_id": "Testis",
"text": "STK11 GENE_EXPRESSED_IN_TISSUE Testis",
"confidence": 0.6937324649
}
] | {
"gene": "STK11",
"top_tissue": "Testis",
"top_tpm": 119.642
} | 0.693732 |
no_tiss_00201 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is FAP most highly expressed? | FAP GENE_EXPRESSED_IN_TISSUE Cells_Cultured_fibroblasts | {
"steps": [
{
"hop": 1,
"source_node_id": "FAP",
"source_node_type": "GENE",
"source_node_label": "FAP",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.6834435079,
"edge_source_db": "GTEx",
"target_node_i... | B | [
"A. Whole_Blood",
"B. Cells_Cultured_fibroblasts",
"C. Brain_Cerebellum",
"D. Brain_Cerebellar_Hemisphere"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "FAP",
"source_db": "UniProt",
"payload": {
"accession": "Q12884",
"sequence": "MKTWVKIVFGVATSAVLALLVMCIVLRPSRVHNSEENTMRALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVNASNYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDL... | [
{
"source_db": "GTEx",
"source_id": "Cells_Cultured_fibroblasts",
"text": "FAP GENE_EXPRESSED_IN_TISSUE Cells_Cultured_fibroblasts",
"confidence": 0.6834435079
}
] | {
"gene": "FAP",
"top_tissue": "Cells_Cultured_fibroblasts",
"top_tpm": 111.364
} | 0.683444 |
no_tiss_00202 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is BRIP1 most highly expressed? | BRIP1 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "BRIP1",
"source_node_type": "GENE",
"source_node_label": "BRIP1",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.3370133372,
"edge_source_db": "GTEx",
"target_no... | D | [
"A. Muscle_Skeletal",
"B. Heart_Left_Ventricle",
"C. Heart_Atrial_Appendage",
"D. Cells_EBV-transformed_lymphocytes"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "BRIP1",
"source_db": "UniProt",
"payload": {
"accession": "Q9BX63",
"sequence": "MSSMWSEYTIGGVKIYFPYKAYPSQLAMMNSILRGLNSKQHCLLESPTGSGKSLALLCSALAWQQSLSGKPADEGVSEKAEVQLSCCCACHSKDFTNNDMNQGTSRHFNYPSTPPSERNGTSSTCQDSPEKTT... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "BRIP1 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 0.3370133372
}
] | {
"gene": "BRIP1",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 9.26092
} | 0.337013 |
no_tiss_00203 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is KIF5A most highly expressed? | KIF5A GENE_EXPRESSED_IN_TISSUE Brain_Cortex | {
"steps": [
{
"hop": 1,
"source_node_id": "KIF5A",
"source_node_type": "GENE",
"source_node_label": "KIF5A",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 1,
"edge_source_db": "GTEx",
"target_node_id": "Br... | A | [
"A. Brain_Cortex",
"B. Whole_Blood",
"C. Liver",
"D. Muscle_Skeletal"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "KIF5A",
"source_db": "UniProt",
"payload": {
"accession": "Q12840",
"sequence": "MAETNNECSIKVLCRFRPLNQAEILRGDKFIPIFQGDDSVVIGGKPYVFDRVFPPNTTQEQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIARDIFNHIYSMDENLEFHIKV... | [
{
"source_db": "GTEx",
"source_id": "Brain_Cortex",
"text": "KIF5A GENE_EXPRESSED_IN_TISSUE Brain_Cortex",
"confidence": 1
}
] | {
"gene": "KIF5A",
"top_tissue": "Brain_Cortex",
"top_tpm": 1160.24
} | 1 |
no_tiss_00204 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is DCTN4 most highly expressed? | DCTN4 GENE_EXPRESSED_IN_TISSUE Brain_Cerebellar_Hemisphere | {
"steps": [
{
"hop": 1,
"source_node_id": "DCTN4",
"source_node_type": "GENE",
"source_node_label": "DCTN4",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.5478468224,
"edge_source_db": "GTEx",
"target_no... | D | [
"A. Liver",
"B. Whole_Blood",
"C. Kidney_Cortex",
"D. Brain_Cerebellar_Hemisphere"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "DCTN4",
"source_db": "UniProt",
"payload": {
"accession": "Q9UJW0",
"sequence": "MASLLQSDRVLYLVQGEKKVRAPLSQLYFCRYCSELRSLECVSHEVDSHYCPSCLENMPSAEAKLKKNRCANCFDCPGCMHTLSTRATSISTQLPDDPAKTTMKKAYYLACGFCRWTSRDVGMADKSVASGGW... | [
{
"source_db": "GTEx",
"source_id": "Brain_Cerebellar_Hemisphere",
"text": "DCTN4 GENE_EXPRESSED_IN_TISSUE Brain_Cerebellar_Hemisphere",
"confidence": 0.5478468224
}
] | {
"gene": "DCTN4",
"top_tissue": "Brain_Cerebellar_Hemisphere",
"top_tpm": 43.033
} | 0.547847 |
no_tiss_00205 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is NRAS most highly expressed? | NRAS GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "NRAS",
"source_node_type": "GENE",
"source_node_label": "NRAS",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.6311424453,
"edge_source_db": "GTEx",
"target_node... | B | [
"A. Muscle_Skeletal",
"B. Cells_EBV-transformed_lymphocytes",
"C. Heart_Left_Ventricle",
"D. Heart_Atrial_Appendage"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "NRAS",
"source_db": "UniProt",
"payload": {
"accession": "P01111",
"sequence": "MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDLPTRTVDTKQAHELA... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "NRAS GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 0.6311424453
}
] | {
"gene": "NRAS",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 77.2891
} | 0.631142 |
no_tiss_00206 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is KRAS most highly expressed? | KRAS GENE_EXPRESSED_IN_TISSUE Nerve_Tibial | {
"steps": [
{
"hop": 1,
"source_node_id": "KRAS",
"source_node_type": "GENE",
"source_node_label": "KRAS",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.5004468095,
"edge_source_db": "GTEx",
"target_node... | A | [
"A. Nerve_Tibial",
"B. Muscle_Skeletal",
"C. Heart_Left_Ventricle",
"D. Pancreas"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "KRAS",
"source_db": "UniProt",
"payload": {
"accession": "P01116",
"sequence": "MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLA... | [
{
"source_db": "GTEx",
"source_id": "Nerve_Tibial",
"text": "KRAS GENE_EXPRESSED_IN_TISSUE Nerve_Tibial",
"confidence": 0.5004468095
}
] | {
"gene": "KRAS",
"top_tissue": "Nerve_Tibial",
"top_tpm": 30.7364
} | 0.500447 |
no_tiss_00207 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is BCOR most highly expressed? | BCOR GENE_EXPRESSED_IN_TISSUE Artery_Tibial | {
"steps": [
{
"hop": 1,
"source_node_id": "BCOR",
"source_node_type": "GENE",
"source_node_label": "BCOR",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.4820658063,
"edge_source_db": "GTEx",
"target_node... | C | [
"A. Brain_Anterior_cingulate_cortex_BA24",
"B. Whole_Blood",
"C. Artery_Tibial",
"D. Brain_Amygdala"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "BCOR",
"source_db": "UniProt",
"payload": {
"accession": "Q6W2J9",
"sequence": "MLSATPLYGNVHSWMNSERVRMCGASEDRKILVNDGDASKARLELREENPLNHNVVDASTAHRIDGLAALSMDRTGLIREGLRVPGNIVYSSLCGLGSEKGREAATSTLGGLGFSSERNPEMQFKPNTPETVEA... | [
{
"source_db": "GTEx",
"source_id": "Artery_Tibial",
"text": "BCOR GENE_EXPRESSED_IN_TISSUE Artery_Tibial",
"confidence": 0.4820658063
}
] | {
"gene": "BCOR",
"top_tissue": "Artery_Tibial",
"top_tpm": 26.9516
} | 0.482066 |
no_tiss_00208 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is AR most highly expressed? | AR GENE_EXPRESSED_IN_TISSUE Cervix_Endocervix | {
"steps": [
{
"hop": 1,
"source_node_id": "AR",
"source_node_type": "GENE",
"source_node_label": "AR",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.5412317495,
"edge_source_db": "GTEx",
"target_node_id"... | A | [
"A. Cervix_Endocervix",
"B. Brain_Cerebellar_Hemisphere",
"C. Cells_EBV-transformed_lymphocytes",
"D. Whole_Blood"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "AR",
"source_db": "UniProt",
"payload": {
"accession": "P10275",
"sequence": "MEVQLGLGRVYPRPPSKTYRGAFQNLFQSVREVIQNPGPRHPEAASAAPPGASLLLLQQQQQQQQQQQQQQQQQQQQQQQETSPRQQQQQQGEDGSPQAHRRGPTGYLVLDEEQQPSQPQSALECHPERGCVPEPG... | [
{
"source_db": "GTEx",
"source_id": "Cervix_Endocervix",
"text": "AR GENE_EXPRESSED_IN_TISSUE Cervix_Endocervix",
"confidence": 0.5412317495
}
] | {
"gene": "AR",
"top_tissue": "Cervix_Endocervix",
"top_tpm": 41.0659
} | 0.541232 |
no_tiss_00209 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is IL22 most highly expressed? | IL22 GENE_EXPRESSED_IN_TISSUE Testis | {
"steps": [
{
"hop": 1,
"source_node_id": "IL22",
"source_node_type": "GENE",
"source_node_label": "IL22",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.0358106216,
"edge_source_db": "GTEx",
"target_node... | D | [
"A. Uterus",
"B. Vagina",
"C. Whole_Blood",
"D. Testis"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "IL22",
"source_db": "UniProt",
"payload": {
"accession": "Q9GZX6",
"sequence": "MAALQKSVSSFLMGTLATSCLLLLALLVQGGAAAPISSHCRLDKSNFQQPYITNRTFMLAKEASLADNNTDVRLIGEKLFHGVSMSERCYLMKQVLNFTLEEVLFPQSDRFQPYMQEVVPFLARLSNRLSTCHI... | [
{
"source_db": "GTEx",
"source_id": "Testis",
"text": "IL22 GENE_EXPRESSED_IN_TISSUE Testis",
"confidence": 0.0358106216
}
] | {
"gene": "IL22",
"top_tissue": "Testis",
"top_tpm": 0.2807
} | 0.035811 |
no_tiss_00210 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is ADORA2A most highly expressed? | ADORA2A GENE_EXPRESSED_IN_TISSUE Brain_Nucleus_accumbens_basal_ganglia | {
"steps": [
{
"hop": 1,
"source_node_id": "ADORA2A",
"source_node_type": "GENE",
"source_node_label": "ADORA2A",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.5501494786,
"edge_source_db": "GTEx",
"targe... | D | [
"A. Pancreas",
"B. Cells_Cultured_fibroblasts",
"C. Muscle_Skeletal",
"D. Brain_Nucleus_accumbens_basal_ganglia"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "ADORA2A",
"source_db": "UniProt",
"payload": {
"accession": "P29274",
"sequence": "MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVL... | [
{
"source_db": "GTEx",
"source_id": "Brain_Nucleus_accumbens_basal_ganglia",
"text": "ADORA2A GENE_EXPRESSED_IN_TISSUE Brain_Nucleus_accumbens_basal_ganglia",
"confidence": 0.5501494786
}
] | {
"gene": "ADORA2A",
"top_tissue": "Brain_Nucleus_accumbens_basal_ganglia",
"top_tpm": 43.7391
} | 0.550149 |
no_tiss_00211 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is FAT4 most highly expressed? | FAT4 GENE_EXPRESSED_IN_TISSUE Cells_Cultured_fibroblasts | {
"steps": [
{
"hop": 1,
"source_node_id": "FAT4",
"source_node_type": "GENE",
"source_node_label": "FAT4",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.4505445257,
"edge_source_db": "GTEx",
"target_node... | C | [
"A. Brain_Cerebellar_Hemisphere",
"B. Cells_EBV-transformed_lymphocytes",
"C. Cells_Cultured_fibroblasts",
"D. Whole_Blood"
] | [
"expression",
"protein_sequence"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "FAT4",
"source_db": "UniProt",
"payload": {
"accession": "Q6V0I7",
"sequence": "MDLAPDRATGRPWLPLHTLSVSQLLRVFWLLSLLPGQAWVHGAEPRQVFQVLEEQPPGTLVGTIQTRPGFTYRLSESHALFAINSSTGALYTTSTIDRESLPSDVINLVVLSSAPTYPTEVRVLVRDLNDNAPV... | [
{
"source_db": "GTEx",
"source_id": "Cells_Cultured_fibroblasts",
"text": "FAT4 GENE_EXPRESSED_IN_TISSUE Cells_Cultured_fibroblasts",
"confidence": 0.4505445257
}
] | {
"gene": "FAT4",
"top_tissue": "Cells_Cultured_fibroblasts",
"top_tpm": 21.4817
} | 0.450545 |
no_tiss_00212 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is ADRB1 most highly expressed? | ADRB1 GENE_EXPRESSED_IN_TISSUE Lung | {
"steps": [
{
"hop": 1,
"source_node_id": "ADRB1",
"source_node_type": "GENE",
"source_node_label": "ADRB1",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.4675979787,
"edge_source_db": "GTEx",
"target_no... | C | [
"A. Whole_Blood",
"B. Cells_Cultured_fibroblasts",
"C. Lung",
"D. Artery_Tibial"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "ADRB1",
"source_db": "UniProt",
"payload": {
"accession": "P08588",
"sequence": "MGAGVLVLGASEPGNLSSAAPLPDGAATAARLLVPASPPASLLPPASESPEPLSQQWTAGMGLLMALIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVVWGRWEYGSFFCEL... | [
{
"source_db": "GTEx",
"source_id": "Lung",
"text": "ADRB1 GENE_EXPRESSED_IN_TISSUE Lung",
"confidence": 0.4675979787
}
] | {
"gene": "ADRB1",
"top_tissue": "Lung",
"top_tpm": 24.2928
} | 0.467598 |
no_tiss_00213 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is CAMLG most highly expressed? | CAMLG GENE_EXPRESSED_IN_TISSUE Ovary | {
"steps": [
{
"hop": 1,
"source_node_id": "CAMLG",
"source_node_type": "GENE",
"source_node_label": "CAMLG",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.6675824836,
"edge_source_db": "GTEx",
"target_no... | C | [
"A. Whole_Blood",
"B. Heart_Left_Ventricle",
"C. Ovary",
"D. Liver"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "CAMLG",
"source_db": "UniProt",
"payload": {
"accession": "P49069",
"sequence": "MESMAVATDGGERPGVPAGSGLSASQRRAELRRRKLLMNSEQRINRIMGFHRPGSGAEEESQTKSKQQDSDKLNSLSVPSVSKRVVLGDSVSTGTTDQQGGVAEVKGTQLGDKLDSFIKPPECSSDVNLELRQ... | [
{
"source_db": "GTEx",
"source_id": "Ovary",
"text": "CAMLG GENE_EXPRESSED_IN_TISSUE Ovary",
"confidence": 0.6675824836
}
] | {
"gene": "CAMLG",
"top_tissue": "Ovary",
"top_tpm": 99.7018
} | 0.667582 |
no_tiss_00214 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is NEK1 most highly expressed? | NEK1 GENE_EXPRESSED_IN_TISSUE Nerve_Tibial | {
"steps": [
{
"hop": 1,
"source_node_id": "NEK1",
"source_node_type": "GENE",
"source_node_label": "NEK1",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.6039591529,
"edge_source_db": "GTEx",
"target_node... | D | [
"A. Pancreas",
"B. Whole_Blood",
"C. Liver",
"D. Nerve_Tibial"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "NEK1",
"source_db": "UniProt",
"payload": {
"accession": "Q96PY6",
"sequence": "MEKYVRLQKIGEGSFGKAILVKSTEDGRQYVIKEINISRMSSKEREESRREVAVLANMKHPNIVQYRESFEENGSLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWFVQICLALKHVHDRKILHRDIKSQNI... | [
{
"source_db": "GTEx",
"source_id": "Nerve_Tibial",
"text": "NEK1 GENE_EXPRESSED_IN_TISSUE Nerve_Tibial",
"confidence": 0.6039591529
}
] | {
"gene": "NEK1",
"top_tissue": "Nerve_Tibial",
"top_tpm": 63.8843
} | 0.603959 |
no_tiss_00215 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is OPTN most highly expressed? | OPTN GENE_EXPRESSED_IN_TISSUE Muscle_Skeletal | {
"steps": [
{
"hop": 1,
"source_node_id": "OPTN",
"source_node_type": "GENE",
"source_node_label": "OPTN",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.8551569045,
"edge_source_db": "GTEx",
"target_node... | A | [
"A. Muscle_Skeletal",
"B. Liver",
"C. Pancreas",
"D. Whole_Blood"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "OPTN",
"source_db": "UniProt",
"payload": {
"accession": "Q96CV9",
"sequence": "MSHQPLSCLTEKEDSPSESTGNGPPHLAHPNLDTFTPEELLQQMKELLTENHQLKEAMKLNNQAMKGRFEELSAWTEKQKEERQFFEIQSKEAKERLMALSHENEKLKEELGKLKGKSERSSEDPTDDSRLPRA... | [
{
"source_db": "GTEx",
"source_id": "Muscle_Skeletal",
"text": "OPTN GENE_EXPRESSED_IN_TISSUE Muscle_Skeletal",
"confidence": 0.8551569045
}
] | {
"gene": "OPTN",
"top_tissue": "Muscle_Skeletal",
"top_tpm": 366.995
} | 0.855157 |
no_tiss_00216 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is BRAF most highly expressed? | BRAF GENE_EXPRESSED_IN_TISSUE Brain_Cerebellar_Hemisphere | {
"steps": [
{
"hop": 1,
"source_node_id": "BRAF",
"source_node_type": "GENE",
"source_node_label": "BRAF",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.4852843643,
"edge_source_db": "GTEx",
"target_node... | D | [
"A. Pancreas",
"B. Liver",
"C. Heart_Left_Ventricle",
"D. Brain_Cerebellar_Hemisphere"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "BRAF",
"source_db": "UniProt",
"payload": {
"accession": "P15056",
"sequence": "MAALSGGGGGGAEPGQALFNGDMEPEAGAGAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLESLGNGTDFSVSSSASMDTVTSSSSSSLSVLPSS... | [
{
"source_db": "GTEx",
"source_id": "Brain_Cerebellar_Hemisphere",
"text": "BRAF GENE_EXPRESSED_IN_TISSUE Brain_Cerebellar_Hemisphere",
"confidence": 0.4852843643
}
] | {
"gene": "BRAF",
"top_tissue": "Brain_Cerebellar_Hemisphere",
"top_tpm": 27.5801
} | 0.485284 |
no_tiss_00217 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is BNIP3 most highly expressed? | BNIP3 GENE_EXPRESSED_IN_TISSUE Pancreas | {
"steps": [
{
"hop": 1,
"source_node_id": "BNIP3",
"source_node_type": "GENE",
"source_node_label": "BNIP3",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.6806024446,
"edge_source_db": "GTEx",
"target_no... | C | [
"A. Colon_Transverse",
"B. Whole_Blood",
"C. Pancreas",
"D. Small_Intestine_Terminal_Ileum"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "BNIP3",
"source_db": "UniProt",
"payload": {
"accession": "Q12983",
"sequence": "MSQNGAPGMQEESLQGSWVELHFSNNGNGGSVPASVSIYNGDMEKILLDAQHESGRSSSKSSHCDSPPRSQTPQDTNRASETDTHSIGEKNSSQSEEDDIERRKEVESILKKNSDWIWDWSSRPENIPPKEFL... | [
{
"source_db": "GTEx",
"source_id": "Pancreas",
"text": "BNIP3 GENE_EXPRESSED_IN_TISSUE Pancreas",
"confidence": 0.6806024446
}
] | {
"gene": "BNIP3",
"top_tissue": "Pancreas",
"top_tpm": 109.18
} | 0.680602 |
no_tiss_00218 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is PARK7 most highly expressed? | PARK7 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "PARK7",
"source_node_type": "GENE",
"source_node_label": "PARK7",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.8278453032,
"edge_source_db": "GTEx",
"target_no... | A | [
"A. Cells_EBV-transformed_lymphocytes",
"B. Whole_Blood",
"C. Pancreas",
"D. Skin_Not_Sun_Exposed_Suprapubic"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "PARK7",
"source_db": "UniProt",
"payload": {
"accession": "Q99497",
"sequence": "MASKRALVILAKGAEEMETVIPVDVMRRAGIKVTVAGLAGKDPVQCSRDVVICPDASLEDAKKEGPYDVVVLPGGNLGAQNLSESAAVKEILKEQENRKGLIAAICAGPTALLAHEIGFGSKVTTHPLAKDKM... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "PARK7 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 0.8278453032
}
] | {
"gene": "PARK7",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 303.716
} | 0.827845 |
no_tiss_00219 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is ZMYM3 most highly expressed? | ZMYM3 GENE_EXPRESSED_IN_TISSUE Ovary | {
"steps": [
{
"hop": 1,
"source_node_id": "ZMYM3",
"source_node_type": "GENE",
"source_node_label": "ZMYM3",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.6120485986,
"edge_source_db": "GTEx",
"target_no... | A | [
"A. Ovary",
"B. Heart_Left_Ventricle",
"C. Pancreas",
"D. Whole_Blood"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "ZMYM3",
"source_db": "UniProt",
"payload": {
"accession": "Q14202",
"sequence": "MDPSDFPSPFDPLTLPEKPLAGDLPVDMEFGEDLLESQTAPTRGWAPPGPSPSSGALDLLDTPAGLEKDPGVLDGATELLGLGGLLYKAPSPPEVDHGPEGTLAWDAGDQTLEPGPGGQTPEVVPPDPGAGAN... | [
{
"source_db": "GTEx",
"source_id": "Ovary",
"text": "ZMYM3 GENE_EXPRESSED_IN_TISSUE Ovary",
"confidence": 0.6120485986
}
] | {
"gene": "ZMYM3",
"top_tissue": "Ovary",
"top_tpm": 67.6138
} | 0.612049 |
no_tiss_00220 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is ESR1 most highly expressed? | ESR1 GENE_EXPRESSED_IN_TISSUE Cervix_Endocervix | {
"steps": [
{
"hop": 1,
"source_node_id": "ESR1",
"source_node_type": "GENE",
"source_node_label": "ESR1",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.651105227,
"edge_source_db": "GTEx",
"target_node_... | A | [
"A. Cervix_Endocervix",
"B. Brain_Putamen_basal_ganglia",
"C. Cells_EBV-transformed_lymphocytes",
"D. Whole_Blood"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "ESR1",
"source_db": "UniProt",
"payload": {
"accession": "P03372",
"sequence": "MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLEN... | [
{
"source_db": "GTEx",
"source_id": "Cervix_Endocervix",
"text": "ESR1 GENE_EXPRESSED_IN_TISSUE Cervix_Endocervix",
"confidence": 0.651105227
}
] | {
"gene": "ESR1",
"top_tissue": "Cervix_Endocervix",
"top_tpm": 88.8666
} | 0.651105 |
no_tiss_00221 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is TBK1 most highly expressed? | TBK1 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "TBK1",
"source_node_type": "GENE",
"source_node_label": "TBK1",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.5698186152,
"edge_source_db": "GTEx",
"target_node... | B | [
"A. Brain_Putamen_basal_ganglia",
"B. Cells_EBV-transformed_lymphocytes",
"C. Heart_Left_Ventricle",
"D. Pancreas"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "TBK1",
"source_db": "UniProt",
"payload": {
"accession": "Q9UHD2",
"sequence": "MQSTSNHLWLLSDILGQGATANVFRGRHKKTGDLFAIKVFNNISFLRPVDVQMREFEVLKKLNHKNIVKLFAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVVGGMNHLRENGIVHR... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "TBK1 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 0.5698186152
}
] | {
"gene": "TBK1",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 50.2511
} | 0.569819 |
no_tiss_00222 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is POLE most highly expressed? | POLE GENE_EXPRESSED_IN_TISSUE Brain_Cerebellum | {
"steps": [
{
"hop": 1,
"source_node_id": "POLE",
"source_node_type": "GENE",
"source_node_label": "POLE",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.6303841024,
"edge_source_db": "GTEx",
"target_node... | B | [
"A. Brain_Amygdala",
"B. Brain_Cerebellum",
"C. Brain_Putamen_basal_ganglia",
"D. Brain_Substantia_nigra"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "POLE",
"source_db": "UniProt",
"payload": {
"accession": "Q07864",
"sequence": "MSLRSGGRRRADPGADGEASRDDGATSSVSALKRLERSQWTDKMDLRFGFERLKEPGEKTGWLINMHPTEILDEDKRLGSAVDYYFIQDDGSRFKVALPYKPYFYIATRKGCEREVSSFLSKKFQGKIAKVETV... | [
{
"source_db": "GTEx",
"source_id": "Brain_Cerebellum",
"text": "POLE GENE_EXPRESSED_IN_TISSUE Brain_Cerebellum",
"confidence": 0.6303841024
}
] | {
"gene": "POLE",
"top_tissue": "Brain_Cerebellum",
"top_tpm": 76.88
} | 0.630384 |
no_tiss_00223 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is FIG4 most highly expressed? | FIG4 GENE_EXPRESSED_IN_TISSUE Artery_Tibial | {
"steps": [
{
"hop": 1,
"source_node_id": "FIG4",
"source_node_type": "GENE",
"source_node_label": "FIG4",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.471815394,
"edge_source_db": "GTEx",
"target_node_... | B | [
"A. Pancreas",
"B. Artery_Tibial",
"C. Heart_Left_Ventricle",
"D. Liver"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "FIG4",
"source_db": "UniProt",
"payload": {
"accession": "Q92562",
"sequence": "MPTAAAPIISSVQKLVLYETRARYFLVGSNNAETKYRVLKIDRTEPKDLVIIDDRHVYTQQEVRELLGRLDLGNRTKMGQKGSSGLFRAVSAFGVVGFVRFLEGYYIVLITKRRKMADIGGHAIYKVEDTNMIY... | [
{
"source_db": "GTEx",
"source_id": "Artery_Tibial",
"text": "FIG4 GENE_EXPRESSED_IN_TISSUE Artery_Tibial",
"confidence": 0.471815394
}
] | {
"gene": "FIG4",
"top_tissue": "Artery_Tibial",
"top_tpm": 25.0406
} | 0.471815 |
no_tiss_00224 | tissue_specific | noncoding_regulatory | easy | 1 | According to GTEx v8, in which tissue is CD274 most highly expressed? | CD274 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes | {
"steps": [
{
"hop": 1,
"source_node_id": "CD274",
"source_node_type": "GENE",
"source_node_label": "CD274",
"edge_relation": "GENE_EXPRESSED_IN_TISSUE",
"edge_evidence_type": "expression",
"edge_confidence": 0.5945511184,
"edge_source_db": "GTEx",
"target_no... | A | [
"A. Cells_EBV-transformed_lymphocytes",
"B. Brain_Amygdala",
"C. Brain_Hippocampus",
"D. Brain_Putamen_basal_ganglia"
] | [
"expression",
"protein_sequence",
"protein_structure"
] | [
{
"family": "sequence",
"tag": "protein_sequence",
"anchor_node_id": "CD274",
"source_db": "UniProt",
"payload": {
"accession": "Q9NZQ7",
"sequence": "MRIFAVFIFMTYWHLLNAFTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEMEDKNIIQFVHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMISYGGADYKRITVKVNAP... | [
{
"source_db": "GTEx",
"source_id": "Cells_EBV-transformed_lymphocytes",
"text": "CD274 GENE_EXPRESSED_IN_TISSUE Cells_EBV-transformed_lymphocytes",
"confidence": 0.5945511184
}
] | {
"gene": "CD274",
"top_tissue": "Cells_EBV-transformed_lymphocytes",
"top_tpm": 59.8011
} | 0.594551 |
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