DATE ADDED TO CATALOG date32 | PUBMEDID int64 | FIRST AUTHOR string | DATE date32 | JOURNAL string | LINK string | STUDY string | DISEASE/TRAIT string | INITIAL SAMPLE SIZE string | REPLICATION SAMPLE SIZE string | REGION string | CHR_ID string | CHR_POS string | REPORTED GENE(S) string | MAPPED_GENE string | UPSTREAM_GENE_ID string | DOWNSTREAM_GENE_ID string | SNP_GENE_IDS string | UPSTREAM_GENE_DISTANCE int64 | DOWNSTREAM_GENE_DISTANCE int64 | STRONGEST SNP-RISK ALLELE string | SNPS string | MERGED int64 | SNP_ID_CURRENT string | CONTEXT string | INTERGENIC int64 | RISK ALLELE FREQUENCY string | P-VALUE float64 | PVALUE_MLOG float64 | P-VALUE (TEXT) string | OR or BETA float64 | 95% CI (TEXT) string | PLATFORM [SNPS PASSING QC] string | CNV string | MAPPED_TRAIT string | MAPPED_TRAIT_URI string | STUDY ACCESSION string | GENOTYPING TECHNOLOGY string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
2008-06-16 | 17,434,096 | Matarin M | 2007-05-06 | Lancet Neurol | www.ncbi.nlm.nih.gov/pubmed/17434096 | A genome-wide genotyping study in patients with ischaemic stroke: initial analysis and data release. | Stroke | 249 European ancestry cases, 268 European ancestry controls | NA | 18p11.21 | 18 | 11987273 | IMPA2 | IMPA2 | null | null | ENSG00000141401 | null | null | rs7506045-? | rs7506045 | 0 | 7506045 | intron_variant | 0 | 0.10 | 0.000001 | 6.154902 | null | 5.39 | [2.77-10.5] | Illumina [408803] | N | stroke | http://www.ebi.ac.uk/efo/EFO_0000712 | GCST000032 | Genome-wide genotyping array |
2008-06-16 | 17,434,096 | Matarin M | 2007-05-06 | Lancet Neurol | www.ncbi.nlm.nih.gov/pubmed/17434096 | A genome-wide genotyping study in patients with ischaemic stroke: initial analysis and data release. | Stroke | 249 European ancestry cases, 268 European ancestry controls | NA | 13q14.3 | 13 | 54006952 | intergenic | LINC00458 | null | null | ENSG00000234787 | null | null | rs9536591-? | rs9536591 | 0 | 9536591 | intron_variant | 0 | 0.10 | 0.000006 | 5.221849 | null | 1.92 | [1.41-2.63] | Illumina [408803] | N | stroke | http://www.ebi.ac.uk/efo/EFO_0000712 | GCST000032 | Genome-wide genotyping array |
2008-06-16 | 17,434,096 | Matarin M | 2007-05-06 | Lancet Neurol | www.ncbi.nlm.nih.gov/pubmed/17434096 | A genome-wide genotyping study in patients with ischaemic stroke: initial analysis and data release. | Stroke | 249 European ancestry cases, 268 European ancestry controls | NA | 6q21 | 6 | 106539495 | AIM1 | CRYBG1 | null | null | ENSG00000112297 | null | null | rs783396-? | rs783396 | 0 | 783396 | missense_variant | 0 | 0.90 | 0.000009 | 5.045757 | null | 2.17 | [1.47-3.13] | Illumina [408803] | N | stroke | http://www.ebi.ac.uk/efo/EFO_0000712 | GCST000032 | Genome-wide genotyping array |
2008-06-16 | 17,434,096 | Matarin M | 2007-05-06 | Lancet Neurol | www.ncbi.nlm.nih.gov/pubmed/17434096 | A genome-wide genotyping study in patients with ischaemic stroke: initial analysis and data release. | Stroke | 249 European ancestry cases, 268 European ancestry controls | NA | 7p21.2 | 7 | 15703161 | intergenic | LINC02587 | null | null | ENSG00000229108 | null | null | rs10486776-? | rs10486776 | 0 | 10486776 | intron_variant | 0 | 0.10 | 0.000006 | 5.221849 | null | 5.62 | [2.66-11.9] | Illumina [408803] | N | stroke | http://www.ebi.ac.uk/efo/EFO_0000712 | GCST000032 | Genome-wide genotyping array |
2014-01-07 | 21,041,247 | Perlis RH | 2010-11-01 | Am J Psychiatry | www.ncbi.nlm.nih.gov/pubmed/21041247 | Genome-wide association study of suicide attempts in mood disorder patients. | Suicide risk | 3,117 European ancestry Bipolar disorder cases, 1,273 European ancestry Major depressive disorder cases | 2,698 European ancestry Bipolar disorder cases, 1,649 Major depressive disorder cases | 21q22.2 | 21 | 39649825 | IGSF5, B3GALT5 | B3GALT5 | null | null | ENSG00000183778 | null | null | rs10854398-C | rs10854398 | 0 | 10854398 | intron_variant | 0 | NR | 0.000006 | 5.221849 | null | 1.178 | null | Affymetrix [1922309] (imputed) | N | mental or behavioural disorder, attempted suicide | http://www.ebi.ac.uk/efo/EFO_0000677, http://www.ebi.ac.uk/efo/EFO_0004321 | GCST000854 | Genome-wide genotyping array |
2014-01-07 | 21,041,247 | Perlis RH | 2010-11-01 | Am J Psychiatry | www.ncbi.nlm.nih.gov/pubmed/21041247 | Genome-wide association study of suicide attempts in mood disorder patients. | Suicide risk | 3,117 European ancestry Bipolar disorder cases, 1,273 European ancestry Major depressive disorder cases | 2,698 European ancestry Bipolar disorder cases, 1,649 Major depressive disorder cases | 2p21 | 2 | 46093955 | intergenic | PRKCE | null | null | ENSG00000171132 | null | null | rs12373805-A | rs12373805 | 0 | 12373805 | intron_variant | 0 | NR | 0.000009 | 5.045757 | null | 1.2169 | null | Affymetrix [1922309] (imputed) | N | mental or behavioural disorder, attempted suicide | http://www.ebi.ac.uk/efo/EFO_0000677, http://www.ebi.ac.uk/efo/EFO_0004321 | GCST000854 | Genome-wide genotyping array |
2014-01-07 | 21,041,247 | Perlis RH | 2010-11-01 | Am J Psychiatry | www.ncbi.nlm.nih.gov/pubmed/21041247 | Genome-wide association study of suicide attempts in mood disorder patients. | Suicide risk | 3,117 European ancestry Bipolar disorder cases, 1,273 European ancestry Major depressive disorder cases | 2,698 European ancestry Bipolar disorder cases, 1,649 Major depressive disorder cases | 10q24.1 | 10 | 95362484 | PDLIM1, SORBS1 | SORBS1 | null | null | ENSG00000095637 | null | null | rs4918918-T | rs4918918 | 0 | 4918918 | intron_variant | 0 | NR | 0.000003 | 5.522879 | null | 1.18 | null | Affymetrix [1922309] (imputed) | N | mental or behavioural disorder, attempted suicide | http://www.ebi.ac.uk/efo/EFO_0000677, http://www.ebi.ac.uk/efo/EFO_0004321 | GCST000854 | Genome-wide genotyping array |
2014-01-07 | 21,041,247 | Perlis RH | 2010-11-01 | Am J Psychiatry | www.ncbi.nlm.nih.gov/pubmed/21041247 | Genome-wide association study of suicide attempts in mood disorder patients. | Suicide risk | 3,117 European ancestry Bipolar disorder cases, 1,273 European ancestry Major depressive disorder cases | 2,698 European ancestry Bipolar disorder cases, 1,649 Major depressive disorder cases | 10p11.23 | 10 | 30201775 | PRKCE | JCAD - RNU6-598P | ENSG00000165757 | ENSG00000200887 | null | 86,281 | 97,794 | rs2462021-C | rs2462021 | 0 | 2462021 | intergenic_variant | 1 | NR | 0.000008 | 5.09691 | null | 1.1755 | null | Affymetrix [1922309] (imputed) | N | mental or behavioural disorder, attempted suicide | http://www.ebi.ac.uk/efo/EFO_0000677, http://www.ebi.ac.uk/efo/EFO_0004321 | GCST000854 | Genome-wide genotyping array |
2011-04-06 | 21,355,061 | Boger CA | 2011-02-25 | J Am Soc Nephrol | www.ncbi.nlm.nih.gov/pubmed/21355061 | CUBN is a gene locus for albuminuria. | Urinary albumin excretion | 31,580 European ancestry individuals | 31,277 European ancestry individuals | 10p13 | 10 | 16877053 | RSU1, CUBN | CUBN | null | null | ENSG00000107611 | null | null | rs1801239-T | rs1801239 | 0 | 1801239 | missense_variant | 0 | 0.90 | 0 | 11 | (UACR) | 0.0835 | [NR] unit decrease CKDGen | Affymetrix, Illumina [~ 2500000] (imputed) | N | albuminuria | http://www.ebi.ac.uk/efo/EFO_0004285 | GCST000988 | Genome-wide genotyping array |
2011-04-04 | 21,326,295 | Jin Y | 2011-02-17 | J Invest Dermatol | www.ncbi.nlm.nih.gov/pubmed/21326295 | Genome-wide analysis identifies a quantitative trait locus in the MHC class II region associated with generalized vitiligo age of onset. | Vitiligo | 1,339 European ancestry cases | 677 European ancestry cases | 6p21.32 | 6 | 32377506 | BTNL2, C6orf10 | TSBP1-AS1 | null | null | ENSG00000225914 | null | null | rs7758128-A | rs7758128 | 0 | 7758128 | intron_variant | 0 | 0.06 | 0 | 10.09691 | null | null | null | Illumina [520460] | N | Vitiligo | http://www.ebi.ac.uk/efo/EFO_0004208 | GCST000981 | Genome-wide genotyping array |
2008-09-15 | 18,262,040 | Sandhu MS | 2008-02-09 | Lancet | www.ncbi.nlm.nih.gov/pubmed/18262040 | LDL-cholesterol concentrations: a genome-wide association study. | LDL cholesterol | 11,685 European ancestry individuals | Up to 4,979 European ancestry individuals | 1p13.3 | 1 | 109279544 | CELSR2, PSRC1 | CELSR2 - PSRC1 | ENSG00000143126 | ENSG00000134222 | null | 3,793 | 1 | rs599839-G | rs599839 | 0 | 599839 | intergenic_variant | 1 | 0.19 | 0 | 33 | null | 0.16 | [0.14-0.18] mmol/L decrease | Affymetrix, Illumina [up to 461986] | N | low density lipoprotein cholesterol measurement | http://www.ebi.ac.uk/efo/EFO_0004611 | GCST000151 | Genome-wide genotyping array |
2008-09-15 | 18,262,040 | Sandhu MS | 2008-02-09 | Lancet | www.ncbi.nlm.nih.gov/pubmed/18262040 | LDL-cholesterol concentrations: a genome-wide association study. | LDL cholesterol | 11,685 European ancestry individuals | Up to 4,979 European ancestry individuals | 19q13.32 | 19 | 44919689 | APOC1 | APOC1 | null | null | ENSG00000130208 | null | null | rs4420638-G | rs4420638 | 0 | 4420638 | intergenic_variant | 0 | 0.18 | 0 | 20 | null | 0.06 | [0.04-0.08] mmol/L increase | Affymetrix, Illumina [up to 461986] | N | low density lipoprotein cholesterol measurement | http://www.ebi.ac.uk/efo/EFO_0004611 | GCST000151 | Genome-wide genotyping array |
2008-09-15 | 18,262,040 | Sandhu MS | 2008-02-09 | Lancet | www.ncbi.nlm.nih.gov/pubmed/18262040 | LDL-cholesterol concentrations: a genome-wide association study. | LDL cholesterol | 11,685 European ancestry individuals | Up to 4,979 European ancestry individuals | 2p24.1 | 2 | 21065449 | APOB | APOB - TDRD15 | ENSG00000084674 | ENSG00000218819 | null | 21,376 | 58,519 | rs562338-T | rs562338 | 0 | 562338 | intron_variant | 1 | 0.20 | 0 | 9 | null | 0.04 | [0.02-0.06] mmol/L decrease | Affymetrix, Illumina [up to 461986] | N | low density lipoprotein cholesterol measurement | http://www.ebi.ac.uk/efo/EFO_0004611 | GCST000151 | Genome-wide genotyping array |
2008-09-12 | 18,245,381 | Uda M | 2008-02-05 | Proc Natl Acad Sci U S A | www.ncbi.nlm.nih.gov/pubmed/18245381 | Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of beta-thalassemia. | Fetal hemoglobin levels | 4,305 European ancestry individuals | 521 European ancestry individuals | 11p15.4 | 11 | 5285279 | HBB | HBE1, HBG2 | null | null | ENSG00000213931, ENSG00000196565 | null | null | rs4910742-A | rs4910742 | 0 | 4910742 | intron_variant | 0 | 0.93 | 0 | 20.69897 | null | 0.58 | [NR] unit decrease | Affymetrix [362129] | N | fetal hemoglobin measurement | http://www.ebi.ac.uk/efo/EFO_0004576 | GCST000150 | Genome-wide genotyping array |
2008-09-12 | 18,245,381 | Uda M | 2008-02-05 | Proc Natl Acad Sci U S A | www.ncbi.nlm.nih.gov/pubmed/18245381 | Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of beta-thalassemia. | Fetal hemoglobin levels | 4,305 European ancestry individuals | 521 European ancestry individuals | 2p16.1 | 2 | 60493111 | BCL11A | BCL11A | null | null | ENSG00000119866 | null | null | rs11886868-T | rs11886868 | 0 | 11886868 | intron_variant | 0 | 0.80 | 0 | 34.154902 | null | 0.48 | [NR] unit decrease | Affymetrix [362129] | N | fetal hemoglobin measurement | http://www.ebi.ac.uk/efo/EFO_0004576 | GCST000150 | Genome-wide genotyping array |
2008-09-16 | 18,239,089 | Kong A | 2008-02-02 | Science | www.ncbi.nlm.nih.gov/pubmed/18239089 | Sequence variants in the RNF212 gene associate with genome-wide recombination rate. | Recombination rate (males) | 1,887 male individuals | 1,248 male individuals | 4p16.3 | 4 | 1101493 | RNF212, SPON2 | RNF212 | null | null | ENSG00000178222 | null | null | rs3796619-T | rs3796619 | 0 | 3796619 | non_coding_transcript_exon_variant | 0 | 0.33 (men and women combined) | 0 | 23.522879 | null | 70.7 | [57.1-84.3] cM decrease | Illumina [309241] | N | recombination rate | http://www.ebi.ac.uk/efo/EFO_0004863 | GCST000148 | Genome-wide genotyping array |
2008-09-17 | 18,239,089 | Kong A | 2008-02-02 | Science | www.ncbi.nlm.nih.gov/pubmed/18239089 | Sequence variants in the RNF212 gene associate with genome-wide recombination rate. | Recombination rate (females) | 1,702 female individuals | 1,663 female individuals | 4p16.3 | 4 | 1084399 | RNF212, SPON2 | RNF212 | null | null | ENSG00000178222 | null | null | rs1670533-C | rs1670533 | 0 | 1670533 | intron_variant | 0 | 0.23 (men and women combined) | 0 | 11.69897 | null | 88.2 | [63.7-112.7] cM increase | Illumina [309241] | N | recombination rate | http://www.ebi.ac.uk/efo/EFO_0004863 | GCST000149 | Genome-wide genotyping array |
2010-12-01 | 20,971,583 | Ojwang JO | 2010-10-22 | J Hand Surg Am | www.ncbi.nlm.nih.gov/pubmed/20971583 | Genome-wide association scan of Dupuytren's disease. | Dupuytren's disease | 37 European ancestry cases, 36 European ancestry controls | NA | 1q41 | 1 | 221443734 | LOC100132626 | LINC02817 - DUSP10 | ENSG00000234754 | ENSG00000143507 | null | 107,245 | 256,935 | rs12032381-C | rs12032381 | 0 | 12032381 | intergenic_variant | 1 | 0.083 | 0.000006 | 5.221849 | null | 6.22 | [2.37-16.31] | Illumina [251837] | N | Dupuytren Contracture | http://www.ebi.ac.uk/efo/EFO_0004229 | GCST000841 | Genome-wide genotyping array |
2010-10-17 | 20,864,672 | Waterworth DM | 2010-09-23 | Arterioscler Thromb Vasc Biol | www.ncbi.nlm.nih.gov/pubmed/20864672 | Genetic variants influencing circulating lipid levels and risk of coronary artery disease. | Triglycerides | up to 17,723 European ancestry individuals | up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals | 2p23.3 | 2 | 27525757 | GCKR | GCKR - SPATA31H1 | ENSG00000084734 | ENSG00000221843 | null | 2,069 | 11,629 | rs1260333-C | rs1260333 | 0 | 1260333 | intergenic_variant | 1 | 0.55 | 0 | 18.69897 | null | 0.05 | [0.04-0.06] unit decrease | Affymetrix, Illumina, Perlegen [2155369] (imputed) | N | triglyceride measurement | http://www.ebi.ac.uk/efo/EFO_0004530 | GCST000809 | Genome-wide genotyping array |
2010-10-17 | 20,864,672 | Waterworth DM | 2010-09-23 | Arterioscler Thromb Vasc Biol | www.ncbi.nlm.nih.gov/pubmed/20864672 | Genetic variants influencing circulating lipid levels and risk of coronary artery disease. | Triglycerides | up to 17,723 European ancestry individuals | up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals | 2p24.1 | 2 | 20981153 | APOB | LINC02850 - APOB | ENSG00000236436 | ENSG00000084674 | null | 119,492 | 20,276 | rs6544366-T | rs6544366 | 0 | 6544366 | intergenic_variant | 1 | 0.22 | 0 | 6.69897 | null | 0.04 | [0.03-0.05] unit decrease | Affymetrix, Illumina, Perlegen [2155369] (imputed) | N | triglyceride measurement | http://www.ebi.ac.uk/efo/EFO_0004530 | GCST000809 | Genome-wide genotyping array |
2010-10-17 | 20,864,672 | Waterworth DM | 2010-09-23 | Arterioscler Thromb Vasc Biol | www.ncbi.nlm.nih.gov/pubmed/20864672 | Genetic variants influencing circulating lipid levels and risk of coronary artery disease. | Triglycerides | up to 17,723 European ancestry individuals | up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals | 8q24.13 | 8 | 125478730 | TRIB1 | TRIB1AL | null | null | ENSG00000253111 | null | null | rs2954029-T | rs2954029 | 0 | 2954029 | intron_variant | 0 | 0.46 | 0 | 10.69897 | null | 0.04 | [0.03-0.05] unit decrease | Affymetrix, Illumina, Perlegen [2155369] (imputed) | N | triglyceride measurement | http://www.ebi.ac.uk/efo/EFO_0004530 | GCST000809 | Genome-wide genotyping array |
2010-10-17 | 20,864,672 | Waterworth DM | 2010-09-23 | Arterioscler Thromb Vasc Biol | www.ncbi.nlm.nih.gov/pubmed/20864672 | Genetic variants influencing circulating lipid levels and risk of coronary artery disease. | Triglycerides | up to 17,723 European ancestry individuals | up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals | 19p13.11 | 19 | 19678719 | CILP2, ZNF101 | ZNF101 | null | null | ENSG00000181896 | null | null | rs2304130-G | rs2304130 | 0 | 2304130 | splice_region_variant | 0 | 0.09 | 0 | 7.39794 | null | 0.07 | [0.04-0.10] unit decrease | Affymetrix, Illumina, Perlegen [2155369] (imputed) | N | triglyceride measurement | http://www.ebi.ac.uk/efo/EFO_0004530 | GCST000809 | Genome-wide genotyping array |
2010-10-17 | 20,864,672 | Waterworth DM | 2010-09-23 | Arterioscler Thromb Vasc Biol | www.ncbi.nlm.nih.gov/pubmed/20864672 | Genetic variants influencing circulating lipid levels and risk of coronary artery disease. | Triglycerides | up to 17,723 European ancestry individuals | up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals | 5q11.2 | 5 | 56558326 | C5orf35 | C5orf67 | null | null | ENSG00000225940 | null | null | rs6867983-T | rs6867983 | 0 | 6867983 | intron_variant | 0 | 0.12 | 0.000003 | 5.522879 | null | 0.02 | [0.01-0.03] unit increase | Affymetrix, Illumina, Perlegen [2155369] (imputed) | N | triglyceride measurement | http://www.ebi.ac.uk/efo/EFO_0004530 | GCST000809 | Genome-wide genotyping array |
2010-10-17 | 20,864,672 | Waterworth DM | 2010-09-23 | Arterioscler Thromb Vasc Biol | www.ncbi.nlm.nih.gov/pubmed/20864672 | Genetic variants influencing circulating lipid levels and risk of coronary artery disease. | Triglycerides | up to 17,723 European ancestry individuals | up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals | 1p31.3 | 1 | 62531167 | DOCK7, ANGPTL3 | DOCK7 | null | null | ENSG00000116641 | null | null | rs1168013-G | rs1168013 | 0 | 1168013 | intron_variant | 0 | 0.65 | 0 | 7.221849 | null | 0.04 | [0.03-0.05] unit increase | Affymetrix, Illumina, Perlegen [2155369] (imputed) | N | triglyceride measurement | http://www.ebi.ac.uk/efo/EFO_0004530 | GCST000809 | Genome-wide genotyping array |
2010-10-17 | 20,864,672 | Waterworth DM | 2010-09-23 | Arterioscler Thromb Vasc Biol | www.ncbi.nlm.nih.gov/pubmed/20864672 | Genetic variants influencing circulating lipid levels and risk of coronary artery disease. | Triglycerides | up to 17,723 European ancestry individuals | up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals | 8p21.3 | 8 | 19970337 | LPL | LPL - RPL30P9 | ENSG00000175445 | ENSG00000242709 | null | 3,070 | 143,006 | rs10105606-C | rs10105606 | 0 | 10105606 | intergenic_variant | 1 | 0.68 | 0 | 25.39794 | null | 0.07 | [0.06-0.08] increase | Affymetrix, Illumina, Perlegen [2155369] (imputed) | N | triglyceride measurement | http://www.ebi.ac.uk/efo/EFO_0004530 | GCST000809 | Genome-wide genotyping array |
2010-10-17 | 20,864,672 | Waterworth DM | 2010-09-23 | Arterioscler Thromb Vasc Biol | www.ncbi.nlm.nih.gov/pubmed/20864672 | Genetic variants influencing circulating lipid levels and risk of coronary artery disease. | Triglycerides | up to 17,723 European ancestry individuals | up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals | 4q22.1 | 4 | 87109109 | AFF1 | AFF1 | null | null | ENSG00000172493 | null | null | rs442177-A | rs442177 | 0 | 442177 | intron_variant | 0 | 0.50 | 0 | 9.522879 | null | 0.02 | [0.01-0.03] unit increase | Affymetrix, Illumina, Perlegen [2155369] (imputed) | N | triglyceride measurement | http://www.ebi.ac.uk/efo/EFO_0004530 | GCST000809 | Genome-wide genotyping array |
2010-10-17 | 20,864,672 | Waterworth DM | 2010-09-23 | Arterioscler Thromb Vasc Biol | www.ncbi.nlm.nih.gov/pubmed/20864672 | Genetic variants influencing circulating lipid levels and risk of coronary artery disease. | Triglycerides | up to 17,723 European ancestry individuals | up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals | 11q12.2 | 11 | 61803876 | FADS1 | FADS2, FADS1 | null | null | ENSG00000134824, ENSG00000149485 | null | null | rs174548-G | rs174548 | 0 | 174548 | intron_variant | 0 | 0.17 | 0 | 13.30103 | null | 0.03 | [0.02-0.04] unit increase | Affymetrix, Illumina, Perlegen [2155369] (imputed) | N | triglyceride measurement | http://www.ebi.ac.uk/efo/EFO_0004530 | GCST000809 | Genome-wide genotyping array |
2010-10-17 | 20,864,672 | Waterworth DM | 2010-09-23 | Arterioscler Thromb Vasc Biol | www.ncbi.nlm.nih.gov/pubmed/20864672 | Genetic variants influencing circulating lipid levels and risk of coronary artery disease. | Triglycerides | up to 17,723 European ancestry individuals | up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals | 7q11.23 | 7 | 73442100 | TBL2, MLXIPL, BAZ1B, BCL7B | BAZ1B | null | null | ENSG00000009954 | null | null | rs1178979-A | rs1178979 | 0 | 1178979 | 3_prime_UTR_variant | 0 | 0.80 | 0 | 11.69897 | null | 0.05 | [0.03-0.07] unit increase | Affymetrix, Illumina, Perlegen [2155369] (imputed) | N | triglyceride measurement | http://www.ebi.ac.uk/efo/EFO_0004530 | GCST000809 | Genome-wide genotyping array |
2010-10-17 | 20,864,672 | Waterworth DM | 2010-09-23 | Arterioscler Thromb Vasc Biol | www.ncbi.nlm.nih.gov/pubmed/20864672 | Genetic variants influencing circulating lipid levels and risk of coronary artery disease. | Triglycerides | up to 17,723 European ancestry individuals | up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals | 11q23.3 | 11 | 116714271 | ZNF259, APOA1, APOC3, APOA4, APOA5, BUD13 | LINC02702 - BUD13 | ENSG00000237937 | ENSG00000137656 | null | 55,976 | 33,899 | rs4938303-T | rs4938303 | 0 | 4938303 | intergenic_variant | 1 | 0.75 | 0 | 20.39794 | null | 0.07 | [0.06-0.08] unit decrease | Affymetrix, Illumina, Perlegen [2155369] (imputed) | N | triglyceride measurement | http://www.ebi.ac.uk/efo/EFO_0004530 | GCST000809 | Genome-wide genotyping array |
2010-10-17 | 20,864,672 | Waterworth DM | 2010-09-23 | Arterioscler Thromb Vasc Biol | www.ncbi.nlm.nih.gov/pubmed/20864672 | Genetic variants influencing circulating lipid levels and risk of coronary artery disease. | LDL cholesterol | up to 17,723 European ancestry individuals | up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals | 1p13.3 | 1 | 109275216 | CELSR2 | CELSR2 | null | null | ENSG00000143126 | null | null | rs660240-A | rs660240 | 0 | 660240 | 3_prime_UTR_variant | 0 | 0.21 | 0 | 26 | null | 0.04 | [0.03-0.05] unit decrease | Affymetrix, Illumina, Perlegen [2155369] (imputed) | N | low density lipoprotein cholesterol measurement | http://www.ebi.ac.uk/efo/EFO_0004611 | GCST000807 | Genome-wide genotyping array |
2010-10-17 | 20,864,672 | Waterworth DM | 2010-09-23 | Arterioscler Thromb Vasc Biol | www.ncbi.nlm.nih.gov/pubmed/20864672 | Genetic variants influencing circulating lipid levels and risk of coronary artery disease. | LDL cholesterol | up to 17,723 European ancestry individuals | up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals | 1p32.3 | 1 | 55030366 | PCSK9 | BSND - PCSK9 | ENSG00000162399 | ENSG00000169174 | null | 13,194 | 9,079 | rs11206510-T | rs11206510 | 0 | 11206510 | intergenic_variant | 1 | 0.77 | 0 | 10 | null | 0.03 | [0.02-0.04] unit increase | Affymetrix, Illumina, Perlegen [2155369] (imputed) | N | low density lipoprotein cholesterol measurement | http://www.ebi.ac.uk/efo/EFO_0004611 | GCST000807 | Genome-wide genotyping array |
2010-10-17 | 20,864,672 | Waterworth DM | 2010-09-23 | Arterioscler Thromb Vasc Biol | www.ncbi.nlm.nih.gov/pubmed/20864672 | Genetic variants influencing circulating lipid levels and risk of coronary artery disease. | LDL cholesterol | up to 17,723 European ancestry individuals | up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals | 2p24.1 | 2 | 21063185 | APOB | APOB - TDRD15 | ENSG00000084674 | ENSG00000218819 | null | 19,112 | 60,783 | rs515135-A | rs515135 | 0 | 515135 | intron_variant | 1 | 0.19 | 0 | 19.69897 | null | 0.04 | [0.03-0.05] unit decrease | Affymetrix, Illumina, Perlegen [2155369] (imputed) | N | low density lipoprotein cholesterol measurement | http://www.ebi.ac.uk/efo/EFO_0004611 | GCST000807 | Genome-wide genotyping array |
2010-10-17 | 20,864,672 | Waterworth DM | 2010-09-23 | Arterioscler Thromb Vasc Biol | www.ncbi.nlm.nih.gov/pubmed/20864672 | Genetic variants influencing circulating lipid levels and risk of coronary artery disease. | LDL cholesterol | up to 17,723 European ancestry individuals | up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals | 5q13.3 | 5 | 75360714 | HMGCR | CERT1, HMGCR | null | null | ENSG00000113163, ENSG00000113161 | null | null | rs12916-T | rs12916 | 0 | 12916 | 3_prime_UTR_variant | 0 | 0.62 | 0 | 11 | null | 0.02 | [0.01-0.03] unit decrease | Affymetrix, Illumina, Perlegen [2155369] (imputed) | N | low density lipoprotein cholesterol measurement | http://www.ebi.ac.uk/efo/EFO_0004611 | GCST000807 | Genome-wide genotyping array |
2010-10-17 | 20,864,672 | Waterworth DM | 2010-09-23 | Arterioscler Thromb Vasc Biol | www.ncbi.nlm.nih.gov/pubmed/20864672 | Genetic variants influencing circulating lipid levels and risk of coronary artery disease. | LDL cholesterol | up to 17,723 European ancestry individuals | up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals | 19q13.32 | 19 | 44919689 | APOC2, APOE, APOC4, APOC1 | APOC1 | null | null | ENSG00000130208 | null | null | rs4420638-G | rs4420638 | 0 | 4420638 | intergenic_variant | 0 | 0.18 | 0 | 39.69897 | null | 0.06 | [0.05-0.07] unit increase | Affymetrix, Illumina, Perlegen [2155369] (imputed) | N | low density lipoprotein cholesterol measurement | http://www.ebi.ac.uk/efo/EFO_0004611 | GCST000807 | Genome-wide genotyping array |
2010-10-17 | 20,864,672 | Waterworth DM | 2010-09-23 | Arterioscler Thromb Vasc Biol | www.ncbi.nlm.nih.gov/pubmed/20864672 | Genetic variants influencing circulating lipid levels and risk of coronary artery disease. | LDL cholesterol | up to 17,723 European ancestry individuals | up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals | 8q24.13 | 8 | 125469835 | TRIB1 | TRIB1AL | null | null | ENSG00000253111 | null | null | rs2954021-G | rs2954021 | 0 | 2954021 | intron_variant | 0 | 0.50 | 0 | 7 | null | 0.02 | [0.01-0.03] unit decrease | Affymetrix, Illumina, Perlegen [2155369] (imputed) | N | low density lipoprotein cholesterol measurement | http://www.ebi.ac.uk/efo/EFO_0004611 | GCST000807 | Genome-wide genotyping array |
2010-10-17 | 20,864,672 | Waterworth DM | 2010-09-23 | Arterioscler Thromb Vasc Biol | www.ncbi.nlm.nih.gov/pubmed/20864672 | Genetic variants influencing circulating lipid levels and risk of coronary artery disease. | LDL cholesterol | up to 17,723 European ancestry individuals | up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals | 11q23.3 | 11 | 116736721 | ZNF259, APOA1, APOC3, APOA4, APOA5, BUD13 | LINC02702 - BUD13 | ENSG00000237937 | ENSG00000137656 | null | 78,426 | 11,449 | rs1558861-T | rs1558861 | 0 | 1558861 | intron_variant | 1 | 0.94 | 0.000002 | 5.69897 | null | 0.03 | [0.02-0.04] unit decrease | Affymetrix, Illumina, Perlegen [2155369] (imputed) | N | low density lipoprotein cholesterol measurement | http://www.ebi.ac.uk/efo/EFO_0004611 | GCST000807 | Genome-wide genotyping array |
2010-10-17 | 20,864,672 | Waterworth DM | 2010-09-23 | Arterioscler Thromb Vasc Biol | www.ncbi.nlm.nih.gov/pubmed/20864672 | Genetic variants influencing circulating lipid levels and risk of coronary artery disease. | LDL cholesterol | up to 17,723 European ancestry individuals | up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals | 19p13.2 | 19 | 11127797 | LDLR | LDLR | null | null | ENSG00000130164 | null | null | rs2738459-C | rs2738459 | 0 | 2738459 | intron_variant | 0 | 0.48 | 0.000007 | 5.154902 | null | 0.02 | [0.01-0.03] unit decrease | Affymetrix, Illumina, Perlegen [2155369] (imputed) | N | low density lipoprotein cholesterol measurement | http://www.ebi.ac.uk/efo/EFO_0004611 | GCST000807 | Genome-wide genotyping array |
2010-10-17 | 20,864,672 | Waterworth DM | 2010-09-23 | Arterioscler Thromb Vasc Biol | www.ncbi.nlm.nih.gov/pubmed/20864672 | Genetic variants influencing circulating lipid levels and risk of coronary artery disease. | LDL cholesterol | up to 17,723 European ancestry individuals | up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals | 8p23.1 | 8 | 9327636 | PPP1R3B | PPP1R3B-DT | null | null | ENSG00000248538 | null | null | rs2126259-A | rs2126259 | 0 | 2126259 | intron_variant | 0 | 0.13 | 0 | 11.154902 | null | 0.02 | [0.01-0.03] unit decrease | Affymetrix, Illumina, Perlegen [2155369] (imputed) | N | low density lipoprotein cholesterol measurement | http://www.ebi.ac.uk/efo/EFO_0004611 | GCST000807 | Genome-wide genotyping array |
2010-10-17 | 20,864,672 | Waterworth DM | 2010-09-23 | Arterioscler Thromb Vasc Biol | www.ncbi.nlm.nih.gov/pubmed/20864672 | Genetic variants influencing circulating lipid levels and risk of coronary artery disease. | LDL cholesterol | up to 17,723 European ancestry individuals | up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals | 19p13.11 | 19 | 19296909 | SF4, CILP2 | SUGP1 | null | null | ENSG00000105705 | null | null | rs10401969-T | rs10401969 | 0 | 10401969 | intron_variant | 0 | 0.91 | 0 | 11 | null | 0.05 | [0.04-0.06] unit increase | Affymetrix, Illumina, Perlegen [2155369] (imputed) | N | low density lipoprotein cholesterol measurement | http://www.ebi.ac.uk/efo/EFO_0004611 | GCST000807 | Genome-wide genotyping array |
2010-10-17 | 20,864,672 | Waterworth DM | 2010-09-23 | Arterioscler Thromb Vasc Biol | www.ncbi.nlm.nih.gov/pubmed/20864672 | Genetic variants influencing circulating lipid levels and risk of coronary artery disease. | LDL cholesterol | up to 17,723 European ancestry individuals | up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals | 6p22.3 | 6 | 16196963 | MYLIP, GMPR | MRPL42P2 - RNU6-1114P | ENSG00000216364 | ENSG00000251831 | null | 24,932 | 8,051 | rs2142672-C | rs2142672 | 0 | 2142672 | intron_variant | 1 | 0.74 | 0 | 7.69897 | null | 0.01 | [0.007-0.015] unit increase | Affymetrix, Illumina, Perlegen [2155369] (imputed) | N | low density lipoprotein cholesterol measurement | http://www.ebi.ac.uk/efo/EFO_0004611 | GCST000807 | Genome-wide genotyping array |
2010-10-17 | 20,864,672 | Waterworth DM | 2010-09-23 | Arterioscler Thromb Vasc Biol | www.ncbi.nlm.nih.gov/pubmed/20864672 | Genetic variants influencing circulating lipid levels and risk of coronary artery disease. | HDL cholesterol | up to 17,723 European ancestry individuals | up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals | 15q21.3 | 15 | 58434545 | LIPC | ALDH1A2, LIPC | null | null | ENSG00000128918, ENSG00000166035 | null | null | rs261334-G | rs261334 | 0 | 261334 | intron_variant | 0 | 0.20 | 0 | 21.30103 | null | 0.03 | [0.02-0.04] unit increase | Affymetrix, Illumina, Perlegen [2155369] (imputed) | N | high density lipoprotein cholesterol measurement | http://www.ebi.ac.uk/efo/EFO_0004612 | GCST000805 | Genome-wide genotyping array |
2010-10-17 | 20,864,672 | Waterworth DM | 2010-09-23 | Arterioscler Thromb Vasc Biol | www.ncbi.nlm.nih.gov/pubmed/20864672 | Genetic variants influencing circulating lipid levels and risk of coronary artery disease. | HDL cholesterol | up to 17,723 European ancestry individuals | up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals | 18q21.1 | 18 | 49655298 | LIPG | SMUG1P1 - ACAA2 | ENSG00000267444 | ENSG00000167315 | null | 4,138 | 126,866 | rs2156552-T | rs2156552 | 0 | 2156552 | intron_variant | 1 | 0.81 | 0 | 11.69897 | null | 0.03 | [0.02-0.04] unit increase | Affymetrix, Illumina, Perlegen [2155369] (imputed) | N | high density lipoprotein cholesterol measurement | http://www.ebi.ac.uk/efo/EFO_0004612 | GCST000805 | Genome-wide genotyping array |
2010-10-17 | 20,864,672 | Waterworth DM | 2010-09-23 | Arterioscler Thromb Vasc Biol | www.ncbi.nlm.nih.gov/pubmed/20864672 | Genetic variants influencing circulating lipid levels and risk of coronary artery disease. | HDL cholesterol | up to 17,723 European ancestry individuals | up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals | 1q42.13 | 1 | 230169242 | GALNT2 | GALNT2 | null | null | ENSG00000143641 | null | null | rs10489615-G | rs10489615 | 0 | 10489615 | intron_variant | 0 | 0.60 | 0 | 8.39794 | null | 0.02 | [0.01-0.03] unit increase | Affymetrix, Illumina, Perlegen [2155369] (imputed) | N | high density lipoprotein cholesterol measurement | http://www.ebi.ac.uk/efo/EFO_0004612 | GCST000805 | Genome-wide genotyping array |
2010-10-17 | 20,864,672 | Waterworth DM | 2010-09-23 | Arterioscler Thromb Vasc Biol | www.ncbi.nlm.nih.gov/pubmed/20864672 | Genetic variants influencing circulating lipid levels and risk of coronary artery disease. | HDL cholesterol | up to 17,723 European ancestry individuals | up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals | 11q23.3 | 11 | 116778201 | ZNF259, APOA1, APOC3, APOA4, APOA5 | ZPR1 | null | null | ENSG00000109917 | null | null | rs964184-G | rs964184 | 0 | 964184 | 3_prime_UTR_variant | 0 | 0.12 | 0 | 10.69897 | null | 0.03 | [0.02-0.04] unit decrease | Affymetrix, Illumina, Perlegen [2155369] (imputed) | N | high density lipoprotein cholesterol measurement | http://www.ebi.ac.uk/efo/EFO_0004612 | GCST000805 | Genome-wide genotyping array |
2010-10-17 | 20,864,672 | Waterworth DM | 2010-09-23 | Arterioscler Thromb Vasc Biol | www.ncbi.nlm.nih.gov/pubmed/20864672 | Genetic variants influencing circulating lipid levels and risk of coronary artery disease. | HDL cholesterol | up to 17,723 European ancestry individuals | up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals | 16q13 | 16 | 56951227 | CETP | HERPUD1 - CETP | ENSG00000051108 | ENSG00000087237 | null | 6,363 | 10,696 | rs9989419-G | rs9989419 | 0 | 9989419 | regulatory_region_variant | 1 | 0.60 | 0 | 32 | null | 0.04 | [0.03-0.05] unit increase | Affymetrix, Illumina, Perlegen [2155369] (imputed) | N | high density lipoprotein cholesterol measurement | http://www.ebi.ac.uk/efo/EFO_0004612 | GCST000805 | Genome-wide genotyping array |
2010-10-17 | 20,864,672 | Waterworth DM | 2010-09-23 | Arterioscler Thromb Vasc Biol | www.ncbi.nlm.nih.gov/pubmed/20864672 | Genetic variants influencing circulating lipid levels and risk of coronary artery disease. | HDL cholesterol | up to 17,723 European ancestry individuals | up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals | 2p24.1 | 2 | 20976028 | APOB | LINC02850 - APOB | ENSG00000236436 | ENSG00000084674 | null | 114,367 | 25,401 | rs11902417-G | rs11902417 | 0 | 11902417 | intergenic_variant | 1 | 0.78 | 0 | 6.39794 | null | 0.02 | [0.01-0.03] unit decrease | Affymetrix, Illumina, Perlegen [2155369] (imputed) | N | high density lipoprotein cholesterol measurement | http://www.ebi.ac.uk/efo/EFO_0004612 | GCST000805 | Genome-wide genotyping array |
2010-10-17 | 20,864,672 | Waterworth DM | 2010-09-23 | Arterioscler Thromb Vasc Biol | www.ncbi.nlm.nih.gov/pubmed/20864672 | Genetic variants influencing circulating lipid levels and risk of coronary artery disease. | HDL cholesterol | up to 17,723 European ancestry individuals | up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals | 11q12.2 | 11 | 61803876 | FADS1 | FADS2, FADS1 | null | null | ENSG00000134824, ENSG00000149485 | null | null | rs174548-G | rs174548 | 0 | 174548 | intron_variant | 0 | 0.17 | 0 | 12 | null | 0.01 | [0.007-0.015] unit decrease | Affymetrix, Illumina, Perlegen [2155369] (imputed) | N | high density lipoprotein cholesterol measurement | http://www.ebi.ac.uk/efo/EFO_0004612 | GCST000805 | Genome-wide genotyping array |
2010-10-17 | 20,864,672 | Waterworth DM | 2010-09-23 | Arterioscler Thromb Vasc Biol | www.ncbi.nlm.nih.gov/pubmed/20864672 | Genetic variants influencing circulating lipid levels and risk of coronary artery disease. | HDL cholesterol | up to 17,723 European ancestry individuals | up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals | 8p21.3 | 8 | 19961817 | LPL | LPL | null | null | ENSG00000175445 | null | null | rs325-T | rs325 | 0 | 325 | intron_variant | 0 | 0.89 | 0 | 25.09691 | null | 0.05 | [0.04-0.06] unit decrease | Affymetrix, Illumina, Perlegen [2155369] (imputed) | N | high density lipoprotein cholesterol measurement | http://www.ebi.ac.uk/efo/EFO_0004612 | GCST000805 | Genome-wide genotyping array |
2010-10-17 | 20,864,672 | Waterworth DM | 2010-09-23 | Arterioscler Thromb Vasc Biol | www.ncbi.nlm.nih.gov/pubmed/20864672 | Genetic variants influencing circulating lipid levels and risk of coronary artery disease. | HDL cholesterol | up to 17,723 European ancestry individuals | up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals | 9p22.3 | 9 | 15296036 | TTC39B | TTC39B | null | null | ENSG00000155158 | null | null | rs643531-C | rs643531 | 0 | 643531 | intron_variant | 0 | 0.07 | 0 | 8.154902 | null | 0.01 | [0.009-0.017] unit decrease | Affymetrix, Illumina, Perlegen [2155369] (imputed) | N | high density lipoprotein cholesterol measurement | http://www.ebi.ac.uk/efo/EFO_0004612 | GCST000805 | Genome-wide genotyping array |
2010-10-17 | 20,864,672 | Waterworth DM | 2010-09-23 | Arterioscler Thromb Vasc Biol | www.ncbi.nlm.nih.gov/pubmed/20864672 | Genetic variants influencing circulating lipid levels and risk of coronary artery disease. | HDL cholesterol | up to 17,723 European ancestry individuals | up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals | 9q31.1 | 9 | 104885374 | ABCA1 | ABCA1 | null | null | ENSG00000165029 | null | null | rs3890182-G | rs3890182 | 0 | 3890182 | intron_variant | 0 | 0.88 | 0.000001 | 6.30103 | null | 0.02 | [0.01-0.03] unit increase | Affymetrix, Illumina, Perlegen [2155369] (imputed) | N | high density lipoprotein cholesterol measurement | http://www.ebi.ac.uk/efo/EFO_0004612 | GCST000805 | Genome-wide genotyping array |
2010-10-17 | 20,864,672 | Waterworth DM | 2010-09-23 | Arterioscler Thromb Vasc Biol | www.ncbi.nlm.nih.gov/pubmed/20864672 | Genetic variants influencing circulating lipid levels and risk of coronary artery disease. | HDL cholesterol | up to 17,723 European ancestry individuals | up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals | 12q24.11 | 12 | 109403135 | UBE3B, MVK, MMAB, MYO1H, KCTD10 | MYO1H | null | null | ENSG00000174527 | null | null | rs9943753-G | rs9943753 | 0 | 9943753 | intron_variant | 0 | 0.63 | 0.000003 | 5.522879 | null | 0.02 | [0.01-0.03] unit increase | Affymetrix, Illumina, Perlegen [2155369] (imputed) | N | high density lipoprotein cholesterol measurement | http://www.ebi.ac.uk/efo/EFO_0004612 | GCST000805 | Genome-wide genotyping array |
2010-10-17 | 20,864,672 | Waterworth DM | 2010-09-23 | Arterioscler Thromb Vasc Biol | www.ncbi.nlm.nih.gov/pubmed/20864672 | Genetic variants influencing circulating lipid levels and risk of coronary artery disease. | HDL cholesterol | up to 17,723 European ancestry individuals | up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals | 16q22.1 | 16 | 67674994 | GFOD2, LCAT | GFOD2 | null | null | ENSG00000141098 | null | null | rs12449157-G | rs12449157 | 0 | 12449157 | 3_prime_UTR_variant | 0 | 0.17 | 0 | 6.69897 | null | 0.02 | [0.01-0.03] unit increase | Affymetrix, Illumina, Perlegen [2155369] (imputed) | N | high density lipoprotein cholesterol measurement | http://www.ebi.ac.uk/efo/EFO_0004612 | GCST000805 | Genome-wide genotyping array |
2013-04-27 | 23,358,156 | Benyamin B | 2013-01-29 | Mol Psychiatry | www.ncbi.nlm.nih.gov/pubmed/23358156 | Childhood intelligence is heritable, highly polygenic and associated with FNBP1L. | Intelligence (childhood) | 12,441 European ancestry children | 5,548 European ancestry children | 4q32.1 | 4 | 159361566 | NR | RAPGEF2 - LINC02233 | ENSG00000109756 | ENSG00000250488 | null | 1,392 | 304,267 | rs6536413-A | rs6536413 | 0 | 6536413 | intron_variant | 1 | 0.13 | 0.000006 | 5.221849 | null | 0.075 | [0.042-0.108] unit decrease | Affymetrix, Illumina [138093] (imputed) | N | intelligence | http://www.ebi.ac.uk/efo/EFO_0004337 | GCST001837 | Genome-wide genotyping array |
2013-04-27 | 23,358,156 | Benyamin B | 2013-01-29 | Mol Psychiatry | www.ncbi.nlm.nih.gov/pubmed/23358156 | Childhood intelligence is heritable, highly polygenic and associated with FNBP1L. | Intelligence (childhood) | 12,441 European ancestry children | 5,548 European ancestry children | 20p12.1 | 20 | 13715482 | NR | ESF1 | null | null | ENSG00000089048 | null | null | rs6042314-C | rs6042314 | 0 | 6042314 | intron_variant | 0 | 0.748 | 0.000007 | 5.154902 | null | 0.058 | [0.033-0.083] unit increase | Affymetrix, Illumina [138093] (imputed) | N | intelligence | http://www.ebi.ac.uk/efo/EFO_0004337 | GCST001837 | Genome-wide genotyping array |
2013-04-27 | 23,358,156 | Benyamin B | 2013-01-29 | Mol Psychiatry | www.ncbi.nlm.nih.gov/pubmed/23358156 | Childhood intelligence is heritable, highly polygenic and associated with FNBP1L. | Intelligence (childhood) | 12,441 European ancestry children | 5,548 European ancestry children | 12p13.32 | 12 | 5022387 | NR | KCNA1 - KCNA5 | ENSG00000111262 | ENSG00000130037 | null | 104,131 | 21,492 | rs16932667-T | rs16932667 | 0 | 16932667 | intron_variant | 1 | 0.66 | 0.000008 | 5.09691 | null | 0.052 | [0.028-0.076] unit increase | Affymetrix, Illumina [138093] (imputed) | N | intelligence | http://www.ebi.ac.uk/efo/EFO_0004337 | GCST001837 | Genome-wide genotyping array |
2013-04-27 | 23,358,156 | Benyamin B | 2013-01-29 | Mol Psychiatry | www.ncbi.nlm.nih.gov/pubmed/23358156 | Childhood intelligence is heritable, highly polygenic and associated with FNBP1L. | Intelligence (childhood) | 12,441 European ancestry children | 5,548 European ancestry children | 1q32.3 | 1 | 212218821 | NR | LINC02608 | null | null | ENSG00000226251 | null | null | rs6540731-A | rs6540731 | 0 | 6540731 | intron_variant | 0 | 0.415 | 0.000009 | 5.045757 | null | 0.05 | [0.028-0.072] unit decrease | Affymetrix, Illumina [138093] (imputed) | N | intelligence | http://www.ebi.ac.uk/efo/EFO_0004337 | GCST001837 | Genome-wide genotyping array |
2013-04-27 | 23,358,156 | Benyamin B | 2013-01-29 | Mol Psychiatry | www.ncbi.nlm.nih.gov/pubmed/23358156 | Childhood intelligence is heritable, highly polygenic and associated with FNBP1L. | Intelligence (childhood) | 12,441 European ancestry children | 5,548 European ancestry children | 2p21 | 2 | 43908175 | NR | LRPPRC | null | null | ENSG00000138095 | null | null | rs13387221-A | rs13387221 | 0 | 13387221 | intron_variant | 0 | 0.187 | 0.000009 | 5.045757 | null | 0.064 | [0.035-0.093] unit increase | Affymetrix, Illumina [138093] (imputed) | N | intelligence | http://www.ebi.ac.uk/efo/EFO_0004337 | GCST001837 | Genome-wide genotyping array |
2013-04-27 | 23,358,156 | Benyamin B | 2013-01-29 | Mol Psychiatry | www.ncbi.nlm.nih.gov/pubmed/23358156 | Childhood intelligence is heritable, highly polygenic and associated with FNBP1L. | Intelligence (childhood) | 12,441 European ancestry children | 5,548 European ancestry children | 8q23.1 | 8 | 106832219 | NR | ABRA - HMGB1P46 | ENSG00000174429 | ENSG00000254146 | null | 61,975 | 340,981 | rs2981205-T | rs2981205 | 0 | 2981205 | intergenic_variant | 1 | 0.226 | 0.000005 | 5.30103 | null | 0.06 | [0.035-0.085] unit decrease | Affymetrix, Illumina [138093] (imputed) | N | intelligence | http://www.ebi.ac.uk/efo/EFO_0004337 | GCST001837 | Genome-wide genotyping array |
2010-12-16 | 21,060,863 | Ikram MK | 2010-10-28 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/21060863 | Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo. | Retinal vascular caliber | 15,358 European ancestry individuals | 6,652 European ancestry individuals | 19q13.33 | 19 | 48725015 | FUT2, IZUMO1, FUT1, CA11, FGF21, FLJ36070, RASIP1 | RASIP1 | null | null | ENSG00000105538 | null | null | rs2287921-T | rs2287921 | 0 | 2287921 | intron_variant | 0 | 0.47 | 0 | 24.69897 | (Retinal venular caliber) | 2.1 | [1.71-2.49] um decrease | Affymetrix, Illumina [2194468] (imputed) | N | eye measurement | http://www.ebi.ac.uk/efo/EFO_0004731 | GCST000847 | Genome-wide genotyping array |
2010-12-16 | 21,060,863 | Ikram MK | 2010-10-28 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/21060863 | Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo. | Retinal vascular caliber | 15,358 European ancestry individuals | 6,652 European ancestry individuals | 6q24.2 | 6 | 142226962 | VTA1, NMBR | VTA1 - LINC02919 | ENSG00000009844 | ENSG00000237494 | null | 2,277 | 24,882 | rs225717-C | rs225717 | 0 | 225717 | intergenic_variant | 1 | 0.23 | 0 | 16 | (Retinal venular caliber) | 1.9 | [1.45-2.35] um decrease | Affymetrix, Illumina [2194468] (imputed) | N | eye measurement | http://www.ebi.ac.uk/efo/EFO_0004731 | GCST000847 | Genome-wide genotyping array |
2010-12-16 | 21,060,863 | Ikram MK | 2010-10-28 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/21060863 | Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo. | Retinal vascular caliber | 15,358 European ancestry individuals | 6,652 European ancestry individuals | 12q24.12 | 12 | 111472415 | SH2B3, ATXN2, PTPN11 | ATXN2 | null | null | ENSG00000204842 | null | null | rs10774625-A | rs10774625 | 0 | 10774625 | intron_variant | 0 | 0.48 | 0 | 12.69897 | (Retinal venular caliber) | 1.5 | [1.11-1.89] um increase | Affymetrix, Illumina [2194468] (imputed) | N | eye measurement | http://www.ebi.ac.uk/efo/EFO_0004731 | GCST000847 | Genome-wide genotyping array |
2010-12-16 | 21,060,863 | Ikram MK | 2010-10-28 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/21060863 | Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo. | Retinal vascular caliber | 15,358 European ancestry individuals | 6,652 European ancestry individuals | 5q14.3 | 5 | 88551768 | MEF2C | MIR9-2HG | null | null | ENSG00000245526 | null | null | rs17421627-G | rs17421627 | 0 | 17421627 | intron_variant | 0 | 0.08 | 0 | 15.154902 | (Retinal venular caliber) | 3 | [2.27-3.73] um increase | Affymetrix, Illumina [2194468] (imputed) | N | eye measurement | http://www.ebi.ac.uk/efo/EFO_0004731 | GCST000847 | Genome-wide genotyping array |
2010-12-16 | 21,060,863 | Ikram MK | 2010-10-28 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/21060863 | Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo. | Retinal vascular caliber | 15,358 European ancestry individuals | 6,652 European ancestry individuals | 8p23.1 | 8 | 11246602 | XKR6, SOX7, GATA4, MTMR9, PINX1 | LINC00529 | null | null | ENSG00000236827 | null | null | rs7824557-G | rs7824557 | 0 | 7824557 | intron_variant | 0 | 0.39 | 0 | 6.39794 | (Retinal venular caliber) | 1 | [0.61-1.39] um increase | Affymetrix, Illumina [2194468] (imputed) | N | eye measurement | http://www.ebi.ac.uk/efo/EFO_0004731 | GCST000847 | Genome-wide genotyping array |
2011-04-11 | 21,423,719 | Speliotes EK | 2011-03-10 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/21423719 | Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits. | Nonalcoholic fatty liver disease | 880 Amish individuals, 6,296 European ancestry individuals | 592 European ancestry cases, 1,405 European ancestry controls | 22q13.31 | 22 | 43928847 | PNPLA3 | PNPLA3 | null | null | ENSG00000100344 | null | null | rs738409-G | rs738409 | 0 | 738409 | missense_variant | 0 | 0.23 | 0 | 33.39794 | (GOLD) | 0.26 | [0.22-0.30] unit increase | Affymetrix, Illumina [~ 2400000] (imputed) | N | non-alcoholic fatty liver disease | http://www.ebi.ac.uk/efo/EFO_0003095 | GCST001008 | Genome-wide genotyping array |
2011-04-07 | 21,408,207 | Chung SA | 2011-03-03 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/21408207 | Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. | Systemic lupus erythematosus | 811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls | NA | 6p21.33 | 6 | 32082981 | TNXB | TNXB | null | null | ENSG00000168477 | null | null | rs1150754-A | rs1150754 | 0 | 1150754 | splice_region_variant | 0 | 0.13 | 0 | 28.221849 | (anti-dsDNA +) | 2.21 | [1.93-2.53] | Illumina [421318] (imputed) | N | systemic lupus erythematosus | http://purl.obolibrary.org/obo/MONDO_0007915 | GCST000996 | Genome-wide genotyping array |
2011-04-07 | 21,408,207 | Chung SA | 2011-03-03 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/21408207 | Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. | Systemic lupus erythematosus | 811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls | NA | 2q32.2 | 2 | 191099907 | STAT4 | STAT4 | null | null | ENSG00000138378 | null | null | rs7574865-T | rs7574865 | 0 | 7574865 | intron_variant | 0 | 0.23 | 0 | 19.69897 | (anti-dsDNA +) | 1.77 | [1.57-1.99] | Illumina [421318] (imputed) | N | systemic lupus erythematosus | http://purl.obolibrary.org/obo/MONDO_0007915 | GCST000996 | Genome-wide genotyping array |
2011-04-07 | 21,408,207 | Chung SA | 2011-03-03 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/21408207 | Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. | Systemic lupus erythematosus | 811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls | NA | 7q32.1 | 7 | 128954129 | IRF5 | IRF5 - TNPO3 | ENSG00000128604 | ENSG00000064419 | null | 4,091 | 51 | rs10488631-C | rs10488631 | 0 | 10488631 | intergenic_variant | 1 | 0.11 | 0 | 17.154902 | (anti-dsDNA +) | 1.92 | [1.66-2.22] | Illumina [421318] (imputed) | N | systemic lupus erythematosus | http://purl.obolibrary.org/obo/MONDO_0007915 | GCST000996 | Genome-wide genotyping array |
2011-04-07 | 21,408,207 | Chung SA | 2011-03-03 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/21408207 | Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. | Systemic lupus erythematosus | 811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls | NA | 1p32.3 | 1 | 53163913 | SLC1A7 | SLC1A7 - CPT2 | ENSG00000162383 | ENSG00000157184 | null | 21,275 | 32,879 | rs6695567-? | rs6695567 | 0 | 6695567 | intergenic_variant | 1 | 0.57 | 0.000004 | 5.39794 | (anti-dsDNA +) | 1.32 | [1.18-1.47] | Illumina [421318] (imputed) | N | systemic lupus erythematosus | http://purl.obolibrary.org/obo/MONDO_0007915 | GCST000996 | Genome-wide genotyping array |
2011-04-07 | 21,408,207 | Chung SA | 2011-03-03 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/21408207 | Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. | Systemic lupus erythematosus | 811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls | NA | 3q26.32 | 3 | 177377284 | intergenic | LINC00578 | null | null | ENSG00000228221 | null | null | rs12629106-? | rs12629106 | 0 | 12629106 | regulatory_region_variant | 0 | 0.81 | 0.000004 | 5.39794 | (case-only) | 1.56 | [1.30-1.89] | Illumina [421318] (imputed) | N | systemic lupus erythematosus | http://purl.obolibrary.org/obo/MONDO_0007915 | GCST000996 | Genome-wide genotyping array |
2011-04-07 | 21,408,207 | Chung SA | 2011-03-03 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/21408207 | Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. | Systemic lupus erythematosus | 811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls | NA | 2q32.2 | 2 | 191099907 | STAT4 | STAT4 | null | null | ENSG00000138378 | null | null | rs7574865-T | rs7574865 | 0 | 7574865 | intron_variant | 0 | 0.28 | 0.000008 | 5.09691 | (case-only) | 1.41 | [1.21-1.63] | Illumina [421318] (imputed) | N | systemic lupus erythematosus | http://purl.obolibrary.org/obo/MONDO_0007915 | GCST000996 | Genome-wide genotyping array |
2011-04-07 | 21,408,207 | Chung SA | 2011-03-03 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/21408207 | Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. | Systemic lupus erythematosus | 811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls | NA | 20p13 | 20 | 2537919 | TMC2 | TMC2 | null | null | ENSG00000149488 | null | null | rs6049839-T | rs6049839 | 0 | 6049839 | intron_variant | 0 | 0.40 | 0.000008 | 5.09691 | (case-only) | 1.37 | [1.19-1.58] | Illumina [421318] (imputed) | N | systemic lupus erythematosus | http://purl.obolibrary.org/obo/MONDO_0007915 | GCST000996 | Genome-wide genotyping array |
2011-04-07 | 21,408,207 | Chung SA | 2011-03-03 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/21408207 | Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. | Systemic lupus erythematosus | 811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls | NA | 8p23.1 | 8 | 11486464 | BLK | FAM167A - BLK | ENSG00000154319 | ENSG00000136573 | null | 10,556 | 430 | rs2736340-T | rs2736340 | 0 | 2736340 | intergenic_variant | 1 | 0.23 | 0 | 6.522879 | (anti-dsDNA +) | 1.38 | [1.23-1.56] | Illumina [421318] (imputed) | N | systemic lupus erythematosus | http://purl.obolibrary.org/obo/MONDO_0007915 | GCST000996 | Genome-wide genotyping array |
2011-04-07 | 21,408,207 | Chung SA | 2011-03-03 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/21408207 | Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. | Systemic lupus erythematosus | 811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls | NA | 1q25.3 | 1 | 183207295 | LAMC2 | LAMC2 | null | null | ENSG00000058085 | null | null | rs525410-? | rs525410 | 0 | 525410 | intron_variant | 0 | 0.49 | 0.000001 | 6.221849 | (anti-dsDNA +) | 1.33 | [1.19-1.47] | Illumina [421318] (imputed) | N | systemic lupus erythematosus | http://purl.obolibrary.org/obo/MONDO_0007915 | GCST000996 | Genome-wide genotyping array |
2011-04-07 | 21,408,207 | Chung SA | 2011-03-03 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/21408207 | Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. | Systemic lupus erythematosus | 811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls | NA | 22q11.21 | 22 | 21585386 | UBE2L3 | UBE2L3 | null | null | ENSG00000185651 | null | null | rs5754217-T | rs5754217 | 0 | 5754217 | intron_variant | 0 | 0.19 | 0.000002 | 5.69897 | (anti-dsDNA +) | 1.38 | [1.21-1.57] | Illumina [421318] (imputed) | N | systemic lupus erythematosus | http://purl.obolibrary.org/obo/MONDO_0007915 | GCST000996 | Genome-wide genotyping array |
2011-04-07 | 21,408,207 | Chung SA | 2011-03-03 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/21408207 | Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. | Systemic lupus erythematosus | 811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls | NA | 1q31.1 | 1 | 189754493 | intergenic | LINC01701 | null | null | ENSG00000232212 | null | null | rs10737562-? | rs10737562 | 0 | 10737562 | intergenic_variant | 0 | 0.50 | 0.000007 | 5.154902 | (anti-dsDNA +) | 1.3 | [1.16-1.45] | Illumina [421318] (imputed) | N | systemic lupus erythematosus | http://purl.obolibrary.org/obo/MONDO_0007915 | GCST000996 | Genome-wide genotyping array |
2011-04-07 | 21,408,207 | Chung SA | 2011-03-03 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/21408207 | Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. | Systemic lupus erythematosus | 811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls | NA | 7q32.1 | 7 | 128977412 | IRF5 | TNPO3 | null | null | ENSG00000064419 | null | null | rs12531711-G | rs12531711 | 0 | 12531711 | intron_variant | 0 | 0.11 | 0 | 8.221849 | (anti-dsDNA -) | 1.58 | [1.36-1.83] | Illumina [421318] (imputed) | N | systemic lupus erythematosus | http://purl.obolibrary.org/obo/MONDO_0007915 | GCST000996 | Genome-wide genotyping array |
2011-04-07 | 21,408,207 | Chung SA | 2011-03-03 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/21408207 | Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. | Systemic lupus erythematosus | 811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls | NA | 2q31.3 | 2 | 180649002 | intergenic | CWC22 - SCHLAP1 | ENSG00000163510 | ENSG00000281131 | null | 641,705 | 43,007 | rs918959-? | rs918959 | 0 | 918959 | intron_variant | 1 | 0.91 | 0.000002 | 5.69897 | (anti-dsDNA -) | 1.72 | [1.39-2.17] | Illumina [421318] (imputed) | N | systemic lupus erythematosus | http://purl.obolibrary.org/obo/MONDO_0007915 | GCST000996 | Genome-wide genotyping array |
2011-04-07 | 21,408,207 | Chung SA | 2011-03-03 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/21408207 | Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. | Systemic lupus erythematosus | 811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls | NA | 11q11 | 11 | 55368743 | OR4A15 | OR4A15 | null | null | ENSG00000181958 | null | null | rs7927370-? | rs7927370 | 0 | 7927370 | missense_variant | 0 | 0.94 | 0.000007 | 5.154902 | (anti-dsDNA -) | 1.92 | [1.45-2.56] | Illumina [421318] (imputed) | N | systemic lupus erythematosus | http://purl.obolibrary.org/obo/MONDO_0007915 | GCST000996 | Genome-wide genotyping array |
2011-04-07 | 21,408,207 | Chung SA | 2011-03-03 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/21408207 | Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. | Systemic lupus erythematosus | 811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls | NA | 6p21.32 | 6 | 32638107 | HLA-DR3 | HLA-DQA1 | null | null | ENSG00000196735 | null | null | rs2187668-A | rs2187668 | 0 | 2187668 | intron_variant | 0 | 0.12 | 0 | 27.221849 | (anti-dsDNA +) | 2.23 | [1.94-2.57] | Illumina [421318] (imputed) | N | systemic lupus erythematosus | http://purl.obolibrary.org/obo/MONDO_0007915 | GCST000996 | Genome-wide genotyping array |
2011-04-07 | 21,408,207 | Chung SA | 2011-03-03 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/21408207 | Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. | Systemic lupus erythematosus | 811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls | NA | 16p11.2 | 16 | 31301932 | ITGAM | ITGAM | null | null | ENSG00000169896 | null | null | rs9888739-T | rs9888739 | 0 | 9888739 | intron_variant | 0 | 0.13 | 0 | 15 | (anti-dsDNA +) | 1.8 | [1.56-2.07] | Illumina [421318] (imputed) | N | systemic lupus erythematosus | http://purl.obolibrary.org/obo/MONDO_0007915 | GCST000996 | Genome-wide genotyping array |
2011-04-07 | 21,408,207 | Chung SA | 2011-03-03 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/21408207 | Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. | Systemic lupus erythematosus | 811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls | NA | 4q25 | 4 | 108801970 | COL25A1 | RCC2P8 - COL25A1 | ENSG00000250185 | ENSG00000188517 | null | 12,191 | 6,755 | rs4956211-A | rs4956211 | 0 | 4956211 | intergenic_variant | 1 | 0.35 | 0.000001 | 6 | (anti-dsDNA +) | 1.33 | [1.19-1.48] | Illumina [421318] (imputed) | N | systemic lupus erythematosus | http://purl.obolibrary.org/obo/MONDO_0007915 | GCST000996 | Genome-wide genotyping array |
2011-04-07 | 21,408,207 | Chung SA | 2011-03-03 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/21408207 | Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. | Systemic lupus erythematosus | 811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls | NA | 5q33.3 | 5 | 160452971 | PTTG1 | MIR3142HG | null | null | ENSG00000253522 | null | null | rs2431697-? | rs2431697 | 0 | 2431697 | intergenic_variant | 0 | 0.56 | 0.000002 | 5.69897 | (anti-dsDNA +) | 1.32 | [1.18-1.47] | Illumina [421318] (imputed) | N | systemic lupus erythematosus | http://purl.obolibrary.org/obo/MONDO_0007915 | GCST000996 | Genome-wide genotyping array |
2011-04-07 | 21,408,207 | Chung SA | 2011-03-03 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/21408207 | Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. | Systemic lupus erythematosus | 811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls | NA | 11p15.5 | 11 | 589564 | KIAA1542 | PHRF1 | null | null | ENSG00000070047 | null | null | rs4963128-? | rs4963128 | 0 | 4963128 | intron_variant | 0 | 0.66 | 0.000004 | 5.39794 | (anti-dsDNA +) | 1.33 | [1.18-1.49] | Illumina [421318] (imputed) | N | systemic lupus erythematosus | http://purl.obolibrary.org/obo/MONDO_0007915 | GCST000996 | Genome-wide genotyping array |
2011-04-07 | 21,408,207 | Chung SA | 2011-03-03 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/21408207 | Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. | Systemic lupus erythematosus | 811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls | NA | 6p21.32 | 6 | 32757416 | HLA-DQA2 | HLA-DQB2 | null | null | ENSG00000232629 | null | null | rs2301271-T | rs2301271 | 0 | 2301271 | intron_variant | 0 | 0.40 | 0 | 11.69897 | (anti-dsDNA -) | 1.47 | [1.32-1.63] | Illumina [421318] (imputed) | N | systemic lupus erythematosus | http://purl.obolibrary.org/obo/MONDO_0007915 | GCST000996 | Genome-wide genotyping array |
2011-04-07 | 21,408,207 | Chung SA | 2011-03-03 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/21408207 | Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. | Systemic lupus erythematosus | 811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls | NA | 12q21.2 | 12 | 76615280 | RPL7AP59 | RPL7AP9 - YWHAQP7 | ENSG00000213272 | ENSG00000271142 | null | 14,810 | 4,106 | rs2669010-A | rs2669010 | 0 | 2669010 | intron_variant | 1 | 0.40 | 0.000005 | 5.30103 | (anti-dsDNA -) | 1.28 | [1.16-1.42] | Illumina [421318] (imputed) | N | systemic lupus erythematosus | http://purl.obolibrary.org/obo/MONDO_0007915 | GCST000996 | Genome-wide genotyping array |
2011-04-07 | 21,408,207 | Chung SA | 2011-03-03 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/21408207 | Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. | Systemic lupus erythematosus | 811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls | NA | 6p21.32 | 6 | 32255481 | NOTCH4, C6orf10 | TSBP1-AS1 | null | null | ENSG00000225914 | null | null | rs3130320-T | rs3130320 | 0 | 3130320 | intron_variant | 0 | 0.39 | 0.000003 | 5.522879 | (case-only) | 1.39 | [1.21-1.60] | Illumina [421318] (imputed) | N | systemic lupus erythematosus | http://purl.obolibrary.org/obo/MONDO_0007915 | GCST000996 | Genome-wide genotyping array |
2011-04-07 | 21,408,207 | Chung SA | 2011-03-03 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/21408207 | Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. | Systemic lupus erythematosus | 811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls | NA | 3q26.31 | 3 | 175243598 | NAALADL2 | NAALADL2, NAALADL2-AS2 | null | null | ENSG00000177694, ENSG00000226779 | null | null | rs1463525-? | rs1463525 | 0 | 1463525 | intron_variant | 0 | 0.43 | 0.000008 | 5.09691 | (case-only) | 1.37 | [1.19-1.59] | Illumina [421318] (imputed) | N | systemic lupus erythematosus | http://purl.obolibrary.org/obo/MONDO_0007915 | GCST000996 | Genome-wide genotyping array |
2011-04-07 | 21,408,207 | Chung SA | 2011-03-03 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/21408207 | Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. | Systemic lupus erythematosus | 811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls | NA | 6p21.32 | 6 | 32696681 | HLA-DQA2, HLA-DQA1 | HLA-DQB1 - MTCO3P1 | ENSG00000179344 | ENSG00000235040 | null | 28,298 | 9,443 | rs2647012-A | rs2647012 | 0 | 2647012 | intergenic_variant | 1 | 0.44 | 0.000008 | 5.09691 | (case-only) | 1.38 | [1.20-1.59] | Illumina [421318] (imputed) | N | systemic lupus erythematosus | http://purl.obolibrary.org/obo/MONDO_0007915 | GCST000996 | Genome-wide genotyping array |
2014-04-26 | 24,105,470 | Wu Y | 2013-10-14 | Hum Mol Genet | www.ncbi.nlm.nih.gov/pubmed/24105470 | A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2. | Adiponectin levels | 7,827 East Asian ancestry individuals | 10,252 East Asian ancestry individuals | 10q26.12 | 10 | 121185572 | WDR11, FGFR2 | LINC01153 | null | null | ENSG00000227143 | null | null | rs3943077-A | rs3943077 | 0 | 3943077 | non_coding_transcript_exon_variant | 0 | 0.567 | 0 | 13.522879 | null | 0.07 | [0.050-0.090] unit increase | Affymetrix, Illumina [~ 2500000] (imputed) | N | adiponectin measurement | http://www.ebi.ac.uk/efo/EFO_0004502 | GCST002233 | Genome-wide genotyping array |
2014-04-26 | 24,105,470 | Wu Y | 2013-10-14 | Hum Mol Genet | www.ncbi.nlm.nih.gov/pubmed/24105470 | A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2. | Adiponectin levels | 7,827 East Asian ancestry individuals | 10,252 East Asian ancestry individuals | 12q13.11 | 12 | 48539450 | OR8S1, LALBA | OR8S1 - OR5BS1 | ENSG00000284723 | ENSG00000198678 | null | 12,880 | 20,432 | rs11168618-T | rs11168618 | 0 | 11168618 | intergenic_variant | 1 | 0.137 | 0 | 7 | null | 0.06 | [0.040-0.080] unit decrease | Affymetrix, Illumina [~ 2500000] (imputed) | N | adiponectin measurement | http://www.ebi.ac.uk/efo/EFO_0004502 | GCST002233 | Genome-wide genotyping array |
2014-04-26 | 24,105,470 | Wu Y | 2013-10-14 | Hum Mol Genet | www.ncbi.nlm.nih.gov/pubmed/24105470 | A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2. | Adiponectin levels | 7,827 East Asian ancestry individuals | 10,252 East Asian ancestry individuals | 6q24.2 | 6 | 142798695 | HIVEP2 | HIVEP2 | null | null | ENSG00000010818 | null | null | rs12211360-A | rs12211360 | 0 | 12211360 | intron_variant | 0 | 0.966 | 0.000006 | 5.221849 | null | 0.16 | [0.10-0.22] unit decrease | Affymetrix, Illumina [~ 2500000] (imputed) | N | adiponectin measurement | http://www.ebi.ac.uk/efo/EFO_0004502 | GCST002233 | Genome-wide genotyping array |
2014-04-26 | 24,105,470 | Wu Y | 2013-10-14 | Hum Mol Genet | www.ncbi.nlm.nih.gov/pubmed/24105470 | A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2. | Adiponectin levels | 7,827 East Asian ancestry individuals | 10,252 East Asian ancestry individuals | 16q23.3 | 16 | 82628663 | CDH13 | CDH13 | null | null | ENSG00000140945 | null | null | rs4783244-T | rs4783244 | 0 | 4783244 | intron_variant | 0 | 0.360 | 0 | 164.154902 | null | 0.33 | [0.31-0.35] unit decrease | Affymetrix, Illumina [~ 2500000] (imputed) | N | adiponectin measurement | http://www.ebi.ac.uk/efo/EFO_0004502 | GCST002233 | Genome-wide genotyping array |
2014-04-26 | 24,105,470 | Wu Y | 2013-10-14 | Hum Mol Genet | www.ncbi.nlm.nih.gov/pubmed/24105470 | A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2. | Adiponectin levels | 7,827 East Asian ancestry individuals | 10,252 East Asian ancestry individuals | 3q27.3 | 3 | 186831906 | ADIPOQ | MCF2L2P1 - ADIPOQ | ENSG00000231982 | ENSG00000181092 | null | 4,569 | 10,798 | rs10937273-A | rs10937273 | 0 | 10937273 | intergenic_variant | 1 | 0.404 | 0 | 21.69897 | null | 0.12 | [0.10-0.14] unit increase | Affymetrix, Illumina [~ 2500000] (imputed) | N | adiponectin measurement | http://www.ebi.ac.uk/efo/EFO_0004502 | GCST002233 | Genome-wide genotyping array |
2014-04-26 | 24,105,470 | Wu Y | 2013-10-14 | Hum Mol Genet | www.ncbi.nlm.nih.gov/pubmed/24105470 | A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2. | Adiponectin levels | 7,827 East Asian ancestry individuals | 10,252 East Asian ancestry individuals | 19q13.11 | 19 | 33398094 | PEPD | PEPD | null | null | ENSG00000124299 | null | null | rs889140-A | rs889140 | 0 | 889140 | intron_variant | 0 | 0.450 | 0 | 11.39794 | null | 0.08 | [0.060-0.100] unit increase | Affymetrix, Illumina [~ 2500000] (imputed) | N | adiponectin measurement | http://www.ebi.ac.uk/efo/EFO_0004502 | GCST002233 | Genome-wide genotyping array |
2014-04-26 | 24,105,470 | Wu Y | 2013-10-14 | Hum Mol Genet | www.ncbi.nlm.nih.gov/pubmed/24105470 | A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2. | Adiponectin levels | 7,827 East Asian ancestry individuals | 10,252 East Asian ancestry individuals | 16q23.2 | 16 | 81501185 | CMIP | CMIP | null | null | ENSG00000153815 | null | null | rs2925979-T | rs2925979 | 0 | 2925979 | intron_variant | 0 | 0.411 | 0 | 9.69897 | null | 0.08 | [0.060-0.100] unit decrease | Affymetrix, Illumina [~ 2500000] (imputed) | N | adiponectin measurement | http://www.ebi.ac.uk/efo/EFO_0004502 | GCST002233 | Genome-wide genotyping array |
2014-04-26 | 24,105,470 | Wu Y | 2013-10-14 | Hum Mol Genet | www.ncbi.nlm.nih.gov/pubmed/24105470 | A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2. | Adiponectin levels | 7,827 East Asian ancestry individuals | 10,252 East Asian ancestry individuals | 12q24.31 | 12 | 124006982 | ZNF664 | RFLNA, ZNF664 | null | null | ENSG00000178882, ENSG00000179195 | null | null | rs1187415-C | rs1187415 | 0 | 1187415 | intron_variant | 0 | 0.920 | 0 | 6.69897 | null | 0.11 | [0.071-0.149] unit decrease | Affymetrix, Illumina [~ 2500000] (imputed) | N | adiponectin measurement | http://www.ebi.ac.uk/efo/EFO_0004502 | GCST002233 | Genome-wide genotyping array |
2014-04-26 | 24,105,470 | Wu Y | 2013-10-14 | Hum Mol Genet | www.ncbi.nlm.nih.gov/pubmed/24105470 | A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2. | Adiponectin levels | 7,827 East Asian ancestry individuals | 10,252 East Asian ancestry individuals | 12q24.31 | 12 | 122903375 | GPR109A | VPS37B - ABCB9 | ENSG00000139722 | ENSG00000150967 | null | 7,248 | 17,576 | rs10847980-T | rs10847980 | 0 | 10847980 | intron_variant | 1 | 0.771 | 0.000007 | 5.154902 | null | 0.06 | [0.040-0.080] unit decrease | Affymetrix, Illumina [~ 2500000] (imputed) | N | adiponectin measurement | http://www.ebi.ac.uk/efo/EFO_0004502 | GCST002233 | Genome-wide genotyping array |
2014-04-26 | 24,105,470 | Wu Y | 2013-10-14 | Hum Mol Genet | www.ncbi.nlm.nih.gov/pubmed/24105470 | A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2. | Adiponectin levels | 7,827 East Asian ancestry individuals | 10,252 East Asian ancestry individuals | 3q27.3 | 3 | 186783859 | ADIPOQ | EIF4A2 | null | null | ENSG00000156976 | null | null | rs266719-T | rs266719 | 0 | 266719 | non_coding_transcript_exon_variant | 0 | 0.096 | 0.000001 | 6.154902 | (Conditioned on rs10937273) | 0.13 | [0.071-0.189] unit increase | Affymetrix, Illumina [~ 2500000] (imputed) | N | adiponectin measurement | http://www.ebi.ac.uk/efo/EFO_0004502 | GCST002233 | Genome-wide genotyping array |
2011-04-06 | 21,390,209 | Hu X | 2011-02-24 | PLoS One | www.ncbi.nlm.nih.gov/pubmed/21390209 | Meta-analysis for genome-wide association study identifies multiple variants at the BIN1 locus associated with late-onset Alzheimer's disease. | Alzheimer's disease (late onset) | 1,831 European ancestry cases, 1,764 European ancestry controls | 751 cases, 751 controls | 2q14.3 | 2 | 127130409 | BIN1 | BIN1 - NIFKP9 | ENSG00000136717 | ENSG00000237630 | null | 22,853 | 39,602 | rs12989701-? | rs12989701 | 0 | 12989701 | intron_variant | 1 | NR | 0 | 9.522879 | null | 1.23 | [NR] | Affymetrix, Illumina [NR] (imputed) | N | Alzheimer disease | http://purl.obolibrary.org/obo/MONDO_0004975 | GCST000986 | Genome-wide genotyping array |
2011-04-06 | 21,390,209 | Hu X | 2011-02-24 | PLoS One | www.ncbi.nlm.nih.gov/pubmed/21390209 | Meta-analysis for genome-wide association study identifies multiple variants at the BIN1 locus associated with late-onset Alzheimer's disease. | Alzheimer's disease (late onset) | 1,831 European ancestry cases, 1,764 European ancestry controls | 751 cases, 751 controls | 2q14.3 | 2 | 127137039 | BIN1 | BIN1 - NIFKP9 | ENSG00000136717 | ENSG00000237630 | null | 29,483 | 32,972 | rs744373-? | rs744373 | 0 | 744373 | intergenic_variant | 1 | NR | 0 | 10 | null | 1.19 | [NR] | Affymetrix, Illumina [NR] (imputed) | N | Alzheimer disease | http://purl.obolibrary.org/obo/MONDO_0004975 | GCST000986 | Genome-wide genotyping array |
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