DATE ADDED TO CATALOG date32 | PUBMEDID int64 | FIRST AUTHOR string | DATE date32 | JOURNAL string | LINK string | STUDY string | DISEASE/TRAIT string | INITIAL SAMPLE SIZE string | REPLICATION SAMPLE SIZE string | REGION string | CHR_ID string | CHR_POS string | REPORTED GENE(S) string | MAPPED_GENE string | UPSTREAM_GENE_ID string | DOWNSTREAM_GENE_ID string | SNP_GENE_IDS string | UPSTREAM_GENE_DISTANCE int64 | DOWNSTREAM_GENE_DISTANCE int64 | STRONGEST SNP-RISK ALLELE string | SNPS string | MERGED int64 | SNP_ID_CURRENT string | CONTEXT string | INTERGENIC int64 | RISK ALLELE FREQUENCY string | P-VALUE float64 | PVALUE_MLOG float64 | P-VALUE (TEXT) string | OR or BETA float64 | 95% CI (TEXT) string | PLATFORM [SNPS PASSING QC] string | CNV string | MAPPED_TRAIT string | MAPPED_TRAIT_URI string | STUDY ACCESSION string | GENOTYPING TECHNOLOGY string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 5p14.3 | 5 | 18483542 | NR | SNORD81 - RN7SL58P | ENSG00000212278 | ENSG00000241552 | null | 247,346 | 63,770 | rs4866334-C | rs4866334 | 0 | 4866334 | intergenic_variant | 1 | 0.0883955067200712 | 0.000004 | 5.39794 | (IGP17) | 0.2533 | [0.15-0.36] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2008-06-16 | 18,179,892 | Wallace C | 2008-01-10 | Am J Hum Genet | www.ncbi.nlm.nih.gov/pubmed/18179892 | Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia. | LDL cholesterol | 1,955 European ancestry hypertensive individuals | 2,033 European ancestry individuals from 519 families, 1,461 European ancestry twins | 1p13.3 | 1 | 109279544 | PSRC1, CELSR2 | CELSR2 - PSRC1 | ENSG00000143126 | ENSG00000134222 | null | 3,793 | 1 | rs599839-G | rs599839 | 0 | 599839 | intergenic_variant | 1 | 0.24 | 0 | 7 | null | 0.95 | [0.93-0.97] mMol/l increase | Affymetrix [400496] | N | low density lipoprotein cholesterol measurement | http://www.ebi.ac.uk/efo/EFO_0004611 | GCST000131 | Genome-wide genotyping array |
2008-06-16 | 18,179,892 | Wallace C | 2008-01-10 | Am J Hum Genet | www.ncbi.nlm.nih.gov/pubmed/18179892 | Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia. | LDL cholesterol | 1,955 European ancestry hypertensive individuals | 2,033 European ancestry individuals from 519 families, 1,461 European ancestry twins | 2p23.3 | 2 | 27518370 | GCKR | GCKR | null | null | ENSG00000084734 | null | null | rs780094-T | rs780094 | 0 | 780094 | intron_variant | 0 | 0.39 | 0.000001 | 6.30103 | null | null | null | Affymetrix [400496] | N | low density lipoprotein cholesterol measurement | http://www.ebi.ac.uk/efo/EFO_0004611 | GCST000131 | Genome-wide genotyping array |
2008-06-16 | 18,179,892 | Wallace C | 2008-01-10 | Am J Hum Genet | www.ncbi.nlm.nih.gov/pubmed/18179892 | Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia. | LDL cholesterol | 1,955 European ancestry hypertensive individuals | 2,033 European ancestry individuals from 519 families, 1,461 European ancestry twins | 11q23.3 | 11 | 116781707 | APOA1, APOC3, APOA5 | ZPR1 | null | null | ENSG00000109917 | null | null | rs6589566-G | rs6589566 | 0 | 6589566 | intron_variant | 0 | 0.06 | 0 | 10.522879 | null | null | null | Affymetrix [400496] | N | low density lipoprotein cholesterol measurement | http://www.ebi.ac.uk/efo/EFO_0004611 | GCST000131 | Genome-wide genotyping array |
2008-06-16 | 18,179,892 | Wallace C | 2008-01-10 | Am J Hum Genet | www.ncbi.nlm.nih.gov/pubmed/18179892 | Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia. | Urate levels | 1,955 European ancestry hypertensive individuals | 2,033 European ancestry individuals from 519 families, 1,461 European ancestry twins | 4p16.1 | 4 | 9964756 | WDR1, SLC2A9 | SLC2A9 | null | null | ENSG00000109667 | null | null | rs7442295-A | rs7442295 | 0 | 7442295 | intron_variant | 0 | 0.79 | 0 | 14.69897 | null | 0.02 | [0.02-0.03] mMol/L increase | Affymetrix [400496] | N | urate measurement | http://www.ebi.ac.uk/efo/EFO_0004531 | GCST000130 | Genome-wide genotyping array |
2015-05-23 | 21,307,088 | Khor CC | 2011-02-09 | Hum Mol Genet | www.ncbi.nlm.nih.gov/pubmed/21307088 | Genome-wide association studies in Asians confirm the involvement of ATOH7 and TGFBR3, and further identify CARD10 as a novel locus influencing optic disc area. | Optic disc area | 2,132 Indian ancestry individuals, 2,313 Malay ancestry individuals | 9,326 European ancestry individuals | 10q21.3 | 10 | 68232096 | ATOH7 | ATOH7 | null | null | ENSG00000179774 | null | null | rs7916697-A | rs7916697 | 0 | 7916697 | 5_prime_UTR_variant | 0 | NR | 0 | 14.69897 | (Asian) | 0.0938 | [NR] mm2 decrease | Illumina [551808] | N | optic disc size trait | http://purl.obolibrary.org/obo/OBA_VT0006216 | GCST000970 | Genome-wide genotyping array |
2015-05-23 | 21,307,088 | Khor CC | 2011-02-09 | Hum Mol Genet | www.ncbi.nlm.nih.gov/pubmed/21307088 | Genome-wide association studies in Asians confirm the involvement of ATOH7 and TGFBR3, and further identify CARD10 as a novel locus influencing optic disc area. | Optic disc area | 2,132 Indian ancestry individuals, 2,313 Malay ancestry individuals | 9,326 European ancestry individuals | 22q13.1 | 22 | 37523260 | CARD10 | CARD10 - CDC42EP1 | ENSG00000100065 | ENSG00000128283 | null | 3,718 | 31,852 | rs9607469-A | rs9607469 | 0 | 9607469 | intron_variant | 1 | 0.14 | 0 | 11.522879 | null | 0.051 | [0.036-0.066] mm2 increase | Illumina [551808] | N | optic disc size trait | http://purl.obolibrary.org/obo/OBA_VT0006216 | GCST000970 | Genome-wide genotyping array |
2015-05-23 | 21,307,088 | Khor CC | 2011-02-09 | Hum Mol Genet | www.ncbi.nlm.nih.gov/pubmed/21307088 | Genome-wide association studies in Asians confirm the involvement of ATOH7 and TGFBR3, and further identify CARD10 as a novel locus influencing optic disc area. | Optic disc area | 2,132 Indian ancestry individuals, 2,313 Malay ancestry individuals | 9,326 European ancestry individuals | 1p22.1 | 1 | 91611540 | CDC7, TGFBR3 | WDR82P2 - HSP90B3P | ENSG00000241318 | ENSG00000203914 | null | 75,947 | 30,976 | rs1192415-G | rs1192415 | 0 | 1192415 | regulatory_region_variant | 1 | NR | 0 | 16.09691 | (Asian) | 0.0959 | [NR] mm2 increase | Illumina [551808] | N | optic disc size trait | http://purl.obolibrary.org/obo/OBA_VT0006216 | GCST000970 | Genome-wide genotyping array |
2015-05-23 | 21,307,088 | Khor CC | 2011-02-09 | Hum Mol Genet | www.ncbi.nlm.nih.gov/pubmed/21307088 | Genome-wide association studies in Asians confirm the involvement of ATOH7 and TGFBR3, and further identify CARD10 as a novel locus influencing optic disc area. | Optic disc area | 2,132 Indian ancestry individuals, 2,313 Malay ancestry individuals | 9,326 European ancestry individuals | 22q13.1 | 22 | 37522465 | CARD10 | CARD10 - CDC42EP1 | ENSG00000100065 | ENSG00000128283 | null | 2,923 | 32,647 | rs6000762-C | rs6000762 | 0 | 6000762 | intergenic_variant | 1 | 0.3 | 0 | 8 | (Asian) | 0.059 | [0.039-0.079] mm2 increase | Illumina [551808] | N | optic disc size trait | http://purl.obolibrary.org/obo/OBA_VT0006216 | GCST000970 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 10p14 | 10 | 9526947 | NR | LINC00709 - HSP90AB7P | ENSG00000230014 | ENSG00000235838 | null | 239,890 | 195,016 | rs17515642-C | rs17515642 | 0 | 17515642 | intergenic_variant | 1 | 0.855118419830281 | 0.000002 | 5.69897 | (IGP21) | 0.2258 | [0.13-0.32] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 11q24.1 | 11 | 123002368 | NR | BSX - SAE1P1 | ENSG00000188909 | ENSG00000213184 | null | 20,534 | 15,270 | rs2126200-C | rs2126200 | 0 | 2126200 | intergenic_variant | 1 | 0.541753456007146 | 0.000007 | 5.154902 | (IGP21) | 0.1392 | [0.078-0.2] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 14q23.3 | 14 | 65308977 | FUT8 | PTBP1P - MIR4708 | ENSG00000259078 | ENSG00000266740 | null | 27,811 | 26,140 | rs11847263-G | rs11847263 | 0 | 11847263 | intron_variant | 1 | 0.393000049217002 | 0 | 22 | (IGP59) | 0.3124 | [0.25-0.37] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 17q21.32 | 17 | 47753582 | NR | TBX21 - OSBPL7 | ENSG00000073861 | ENSG00000006025 | null | 7,456 | 53,785 | rs12950390-C | rs12950390 | 0 | 12950390 | intergenic_variant | 1 | 0.252525314541387 | 0.000003 | 5.522879 | (IGP59) | 0.1687 | [0.098-0.239] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 12q24.31 | 12 | 122929802 | NR | ABCB9 | null | null | ENSG00000150967 | null | null | rs2270788-C | rs2270788 | 0 | 2270788 | 3_prime_UTR_variant | 0 | 0.0991554951230425 | 0.000007 | 5.154902 | (IGP59) | 0.2364 | [0.13-0.34] unit increase | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 6p21.32 | 6 | 32730008 | NR | MTCO3P1 - HLA-DQB3 | ENSG00000235040 | ENSG00000226030 | null | 23,053 | 750 | rs2859113-C | rs2859113 | 0 | 2859113 | intergenic_variant | 1 | 0.378328302013423 | 0 | 7.221849 | (IGP59) | 0.1817 | [0.12-0.25] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 6p21.32 | 6 | 32985503 | NR | BRD2 - HLA-DOA | ENSG00000204256 | ENSG00000204252 | null | 3,998 | 18,675 | rs3097645-C | rs3097645 | 0 | 3097645 | intergenic_variant | 1 | 0.87438328769575 | 0.000007 | 5.154902 | (IGP59) | 0.2057 | [0.12-0.3] unit increase | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 7p12.2 | 7 | 50310671 | NR | IKZF1 | null | null | ENSG00000185811 | null | null | rs6583437-G | rs6583437 | 0 | 6583437 | intron_variant | 0 | 0.636650594183445 | 0 | 9 | (IGP59) | 0.1949 | [0.13-0.26] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 17q21.32 | 17 | 47273752 | NR | ITGB3 | null | null | ENSG00000259207 | null | null | rs7209700-G | rs7209700 | 0 | 7209700 | intron_variant | 0 | 0.308782806263982 | 0 | 6.39794 | (IGP59) | 0.1681 | [0.1-0.23] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 11p11.2 | 11 | 45062980 | NR | LINC02685 - PRDM11 | ENSG00000254654 | ENSG00000019485 | null | 84,952 | 32,826 | rs7951911-G | rs7951911 | 0 | 7951911 | intergenic_variant | 1 | 0.0838039874720358 | 0.000008 | 5.09691 | (IGP59) | 0.2689 | [0.15-0.39] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 13q34 | 13 | 113804266 | NR | TMEM255B | null | null | ENSG00000184497 | null | null | rs9329350-G | rs9329350 | 0 | 9329350 | intron_variant | 0 | 0.941389270067114 | 0.000008 | 5.09691 | (IGP59) | 0.3006 | [0.17-0.43] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 7q21.13 | 7 | 89065756 | NR | ZNF804B | null | null | ENSG00000182348 | null | null | rs10236237-T | rs10236237 | 0 | 10236237 | intron_variant | 0 | 0.267901504028648 | 0.000007 | 5.154902 | (IGP6) | 0.1584 | [0.089-0.228] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 14q23.3 | 14 | 65308977 | FUT8 | PTBP1P - MIR4708 | ENSG00000259078 | ENSG00000266740 | null | 27,811 | 26,140 | rs11847263-G | rs11847263 | 0 | 11847263 | intron_variant | 1 | 0.394040135631155 | 0 | 14.30103 | (IGP6) | 0.2482 | [0.19-0.31] unit increase | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 6p21.33 | 6 | 31605179 | NR | NCR3 - UQCRHP1 | ENSG00000204475 | ENSG00000230622 | null | 11,962 | 5,904 | rs2844479-C | rs2844479 | 0 | 2844479 | intergenic_variant | 1 | 0.393631380483438 | 0.000004 | 5.39794 | (IGP6) | 0.1506 | [0.086-0.215] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 18q22.3 | 18 | 71712154 | NR | LINC01541 - LINC01899 | ENSG00000260676 | ENSG00000265352 | null | 133,151 | 20,440 | rs2887004-G | rs2887004 | 0 | 2887004 | intergenic_variant | 1 | 0.180826079677708 | 0.000006 | 5.221849 | (IGP6) | 0.1862 | [0.11-0.27] unit increase | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 7p12.2 | 7 | 50310671 | NR | IKZF1 | null | null | ENSG00000185811 | null | null | rs6583437-G | rs6583437 | 0 | 6583437 | intron_variant | 0 | 0.637609347358997 | 0 | 8 | (IGP6) | 0.1817 | [0.12-0.24] unit increase | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 7q21.13 | 7 | 89065756 | NR | ZNF804B | null | null | ENSG00000182348 | null | null | rs10236237-T | rs10236237 | 0 | 10236237 | intron_variant | 0 | 0.26751565049416 | 0.000006 | 5.221849 | (IGP60) | 0.16 | [0.091-0.229] unit increase | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 14q23.3 | 14 | 65308977 | FUT8 | PTBP1P - MIR4708 | ENSG00000259078 | ENSG00000266740 | null | 27,811 | 26,140 | rs11847263-G | rs11847263 | 0 | 11847263 | intron_variant | 1 | 0.393211372416891 | 0 | 13.522879 | (IGP60) | 0.2402 | [0.18-0.3] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 4q26 | 4 | 116928293 | NR | RNU6-119P - TRAM1L1 | ENSG00000201752 | ENSG00000174599 | null | 88,908 | 155,261 | rs2389339-G | rs2389339 | 0 | 2389339 | intron_variant | 1 | 0.790576647349506 | 0.000003 | 5.522879 | (IGP60) | 0.18 | [0.1-0.26] unit increase | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 6p21.33 | 6 | 31605179 | NR | NCR3 - UQCRHP1 | ENSG00000204475 | ENSG00000230622 | null | 11,962 | 5,904 | rs2844479-C | rs2844479 | 0 | 2844479 | intergenic_variant | 1 | 0.393698650943396 | 0.000004 | 5.39794 | (IGP60) | 0.151 | [0.087-0.215] unit increase | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 7p12.2 | 7 | 50310671 | NR | IKZF1 | null | null | ENSG00000185811 | null | null | rs6583437-G | rs6583437 | 0 | 6583437 | intron_variant | 0 | 0.637881567834681 | 0 | 8.30103 | (IGP60) | 0.1862 | [0.12-0.25] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 5q15 | 5 | 95905518 | NR | ELL2 | null | null | ENSG00000118985 | null | null | rs10069748-C | rs10069748 | 0 | 10069748 | intron_variant | 0 | 0.274419212661614 | 0.000005 | 5.30103 | (IGP61) | 0.1539 | [0.088-0.22] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 18q22.3 | 18 | 71698064 | NR | LINC01541 - LINC01899 | ENSG00000260676 | ENSG00000265352 | null | 119,061 | 34,530 | rs11665307-C | rs11665307 | 0 | 11665307 | intergenic_variant | 1 | 0.173309217119929 | 0 | 6.522879 | (IGP61) | 0.2071 | [0.13-0.29] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 14q23.3 | 14 | 65308977 | FUT8 | PTBP1P - MIR4708 | ENSG00000259078 | ENSG00000266740 | null | 27,811 | 26,140 | rs11847263-G | rs11847263 | 0 | 11847263 | intron_variant | 1 | 0.393162371823451 | 0 | 16.522879 | (IGP61) | 0.2676 | [0.21-0.33] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 19p13.2 | 19 | 11544195 | NR | CNN1 | null | null | ENSG00000130176 | null | null | rs11880637-T | rs11880637 | 0 | 11880637 | intron_variant | 0 | 0.011251 | 0.000006 | 5.221849 | (IGP61) | 3.9379 | [2.24-5.64] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 5q11.2 | 5 | 51877490 | NR | HMGB1P47 - RNA5SP182 | ENSG00000249338 | ENSG00000251873 | null | 467,285 | 9,198 | rs17835853-G | rs17835853 | 0 | 17835853 | intron_variant | 1 | 0.956794057690593 | 0.000004 | 5.39794 | (IGP30) | 0.4778 | [0.27-0.68] unit increase | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 14q32.33 | 14 | 104880570 | NR | CEP170B | null | null | ENSG00000099814 | null | null | rs2841233-C | rs2841233 | 0 | 2841233 | intron_variant | 0 | 0.642908958091841 | 0.000007 | 5.154902 | (IGP30) | 0.1475 | [0.083-0.212] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 19p13.11 | 19 | 19165550 | NR | MEF2B, BORCS8-MEF2B | null | null | ENSG00000213999, ENSG00000064489 | null | null | rs7249142-G | rs7249142 | 0 | 7249142 | intron_variant | 0 | 0.619273395452519 | 0.000009 | 5.045757 | (IGP30) | 0.1523 | [0.085-0.219] unit increase | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 5q23.1 | 5 | 116398108 | NR | COMMD10 | null | null | ENSG00000145781 | null | null | rs7734156-C | rs7734156 | 0 | 7734156 | intergenic_variant | 0 | 0.0499571860008917 | 0.000007 | 5.154902 | (IGP30) | 0.3437 | [0.19-0.49] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 7p14.1 | 7 | 41997238 | NR | GLI3 | null | null | ENSG00000106571 | null | null | rs846271-C | rs846271 | 0 | 846271 | intron_variant | 0 | 0.628956223807401 | 0.000002 | 5.69897 | (IGP30) | 0.1538 | [0.09-0.218] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 22q13.1 | 22 | 39463164 | MGAT3, TAB1, CACNA1I, SYNGR1 | MGAT3 | null | null | ENSG00000128268 | null | null | rs909674-C | rs909674 | 0 | 909674 | intron_variant | 0 | 0.299100489968792 | 0.000002 | 5.69897 | (IGP30) | 0.1606 | [0.095-0.227] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 6p21.2 | 6 | 37564327 | NR | MIR4462 - MDGA1 | ENSG00000263926 | ENSG00000112139 | null | 8,905 | 66,352 | rs9394438-G | rs9394438 | 0 | 9394438 | intergenic_variant | 1 | 0.713317013374944 | 0.000007 | 5.154902 | (IGP30) | 0.1671 | [0.094-0.24] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 14q31.1 | 14 | 81168979 | NR | TSHR-AS1 | null | null | ENSG00000284959 | null | null | rs10131728-C | rs10131728 | 0 | 10131728 | intron_variant | 0 | 0.872444873552983 | 0 | 6.69897 | (IGP31) | 0.2398 | [0.15-0.33] unit increase | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 12q14.1 | 12 | 62424701 | NR | USP15 - MON2 | ENSG00000135655 | ENSG00000061987 | null | 7,270 | 42,098 | rs10877839-C | rs10877839 | 0 | 10877839 | intergenic_variant | 1 | 0.32479838824577 | 0.000009 | 5.045757 | (IGP31) | 0.1459 | [0.082-0.21] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 12q12 | 12 | 38859306 | NR | CPNE8 | null | null | ENSG00000139117 | null | null | rs11169838-C | rs11169838 | 0 | 11169838 | intron_variant | 0 | 0.680521641139804 | 0.000002 | 5.69897 | (IGP31) | 0.1764 | [0.1-0.25] unit increase | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 3q27.3 | 3 | 187008099 | ST6GAL1 | ST6GAL1 | null | null | ENSG00000073849 | null | null | rs11710456-G | rs11710456 | 0 | 11710456 | intron_variant | 0 | 0.699014551202137 | 0 | 16.221849 | (IGP31) | 0.2934 | [0.22-0.36] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 8p23.3 | 8 | 616207 | NR | ERICH1 | null | null | ENSG00000104714 | null | null | rs17666538-C | rs17666538 | 0 | 17666538 | intergenic_variant | 0 | 0.073151367141585 | 0.000007 | 5.154902 | (IGP31) | 0.2848 | [0.16-0.41] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 6q21 | 6 | 107339442 | NR | PDSS2 | null | null | ENSG00000164494 | null | null | rs2430457-G | rs2430457 | 0 | 2430457 | intron_variant | 0 | 0.00697800000000004 | 0.000005 | 5.30103 | (IGP31) | 2.6041 | [1.48-3.73] unit increase | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 5q15 | 5 | 95318169 | NR | MCTP1 - FAM81B | ENSG00000175471 | ENSG00000153347 | null | 33,075 | 73,197 | rs255982-G | rs255982 | 0 | 255982 | intergenic_variant | 1 | 0.848905209260908 | 0.000008 | 5.09691 | (IGP31) | 0.2077 | [0.12-0.3] unit increase | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 9p21.1 | 9 | 33139455 | NR | B4GALT1 | null | null | ENSG00000086062 | null | null | rs3780486-C | rs3780486 | 0 | 3780486 | intron_variant | 0 | 0.737357337934105 | 0.000001 | 6 | (IGP31) | 0.1725 | [0.1-0.24] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 3q25.31 | 3 | 155549651 | NR | PLCH1 | null | null | ENSG00000114805 | null | null | rs3851357-G | rs3851357 | 0 | 3851357 | intron_variant | 0 | 0.805635591718611 | 0.000009 | 5.045757 | (IGP31) | 0.1814 | [0.1-0.26] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 1p31.1 | 1 | 79043424 | NR | ADGRL4 | null | null | ENSG00000162618 | null | null | rs6687262-C | rs6687262 | 0 | 6687262 | intergenic_variant | 0 | 0.552969396260018 | 0.000002 | 5.69897 | (IGP31) | 0.1461 | [0.085-0.207] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 11p15.4 | 11 | 5604373 | NR | TRIM6, TRIM6-TRIM34 | null | null | ENSG00000121236, ENSG00000258588 | null | null | rs7108470-G | rs7108470 | 0 | 7108470 | intron_variant | 0 | 0.423505770703473 | 0.000003 | 5.522879 | (IGP31) | 0.1516 | [0.088-0.215] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 2q23.3 | 2 | 152580056 | NR | FMNL2 | null | null | ENSG00000157827 | null | null | rs11675841-C | rs11675841 | 0 | 11675841 | intron_variant | 0 | 0.607345676902537 | 0.000005 | 5.30103 | (IGP70) | 0.1458 | [0.083-0.208] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 10p13 | 10 | 13319976 | NR | SEPHS1 | null | null | ENSG00000086475 | null | null | rs1747683-G | rs1747683 | 0 | 1747683 | intron_variant | 0 | 0.414548764129951 | 0.000001 | 6.221849 | (IGP70) | 0.1581 | [0.096-0.22] unit increase | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 22q11.23 | 22 | 23828809 | SMARCB1, DERL3 | SMARCB1 | null | null | ENSG00000099956 | null | null | rs2186369-G | rs2186369 | 0 | 2186369 | intron_variant | 0 | 0.189496820649755 | 0 | 16 | (IGP70) | 0.3451 | [0.26-0.43] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 20p12.1 | 20 | 17848636 | NR | BANF2 - RNU6-192P | ENSG00000125888 | ENSG00000212555 | null | 112,765 | 55,126 | rs2745851-G | rs2745851 | 0 | 2745851 | regulatory_region_variant | 1 | 0.639172889630619 | 0.000009 | 5.045757 | (IGP70) | 0.1435 | [0.08-0.207] unit increase | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 16p13.11 | 16 | 16162910 | NR | ABCC6 | null | null | ENSG00000091262 | null | null | rs3213473-G | rs3213473 | 0 | 3213473 | intron_variant | 0 | 0.851097327102804 | 0.000007 | 5.154902 | (IGP70) | 0.2016 | [0.11-0.29] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 1p31.3 | 1 | 68461830 | NR | RPE65 - DEPDC1 | ENSG00000116745 | ENSG00000024526 | null | 10,727 | 12,322 | rs435066-C | rs435066 | 0 | 435066 | intergenic_variant | 1 | 0.196103507788162 | 0.000005 | 5.30103 | (IGP70) | 0.1801 | [0.1-0.26] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 3p13 | 3 | 72468889 | NR | RYBP - RNU1-62P | ENSG00000163602 | ENSG00000199469 | null | 22,268 | 107,802 | rs9832314-G | rs9832314 | 0 | 9832314 | intron_variant | 1 | 0.055934898976413 | 0.000009 | 5.045757 | (IGP66) | 0.2992 | [0.17-0.43] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 22q11.23 | 22 | 23828809 | SMARCB1, DERL3 | SMARCB1 | null | null | ENSG00000099956 | null | null | rs2186369-G | rs2186369 | 0 | 2186369 | intron_variant | 0 | 0.189580990204809 | 0 | 14.09691 | (IGP68) | 0.324 | [0.24-0.41] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 22q13.1 | 22 | 39463164 | MGAT3, TAB1, CACNA1I, SYNGR1 | MGAT3 | null | null | ENSG00000128268 | null | null | rs909674-C | rs909674 | 0 | 909674 | intron_variant | 0 | 0.298923976402493 | 0 | 9.221849 | (IGP68) | 0.2094 | [0.14-0.28] unit increase | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 5q11.2 | 5 | 56027067 | IL6ST, ANKRD55 | IL6ST-DT - ANKRD55 | ENSG00000227908 | ENSG00000164512 | null | 23,418 | 72,613 | rs17348299-C | rs17348299 | 0 | 17348299 | intron_variant | 1 | 0.836804684351315 | 0.000002 | 5.69897 | (IGP69) | 0.2129 | [0.12-0.3] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 2p21 | 2 | 46323630 | NR | EPAS1 | null | null | ENSG00000116016 | null | null | rs7582701-C | rs7582701 | 0 | 7582701 | intron_variant | 0 | 0.0373370440481498 | 0.000001 | 6 | (IGP69) | 0.4547 | [0.27-0.64] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 3p12.3 | 3 | 76676752 | NR | ROBO2 | null | null | ENSG00000185008 | null | null | rs10511052-G | rs10511052 | 0 | 10511052 | intron_variant | 0 | 0.950688225100133 | 0.000006 | 5.221849 | (IGP7) | 0.3598 | [0.2-0.52] unit increase | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 5p13.2 | 5 | 36473135 | NR | RANBP3L - RNA5SP181 | ENSG00000164188 | ENSG00000222178 | null | 171,021 | 12,208 | rs2937550-C | rs2937550 | 0 | 2937550 | intergenic_variant | 1 | 0.537253260908281 | 0.000009 | 5.045757 | (IGP72) | 0.1807 | [0.1-0.26] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 22q13.1 | 22 | 39463164 | MGAT3, TAB1, CACNA1I, SYNGR1 | MGAT3 | null | null | ENSG00000128268 | null | null | rs909674-C | rs909674 | 0 | 909674 | intron_variant | 0 | 0.299146275601069 | 0 | 14.69897 | (IGP72) | 0.2695 | [0.2-0.34] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 7p21.3 | 7 | 11251773 | NR | PHF14 - NPM1P11 | ENSG00000106443 | ENSG00000226827 | null | 82,150 | 5,908 | rs4720952-G | rs4720952 | 0 | 4720952 | intergenic_variant | 1 | 0.419614954873646 | 0 | 6.39794 | (IGP73) | 0.1566 | [0.096-0.217] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 15q24.1 | 15 | 73457267 | NR | REC114 | null | null | ENSG00000183324 | null | null | rs11635553-G | rs11635553 | 0 | 11635553 | intron_variant | 0 | 0.992804206752874 | 0.000004 | 5.39794 | (IGP74) | 1.0812 | [0.62-1.54] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 5q11.2 | 5 | 56027067 | IL6ST, ANKRD55 | IL6ST-DT - ANKRD55 | ENSG00000227908 | ENSG00000164512 | null | 23,418 | 72,613 | rs17348299-C | rs17348299 | 0 | 17348299 | intron_variant | 1 | 0.836669484361037 | 0.000002 | 5.69897 | (IGP74) | 0.2132 | [0.13-0.3] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 5q12.1 | 5 | 61729255 | NR | LINC03122 | null | null | ENSG00000178722 | null | null | rs4699982-T | rs4699982 | 0 | 4699982 | intron_variant | 0 | 0.158658866845398 | 0.000009 | 5.045757 | (IGP74) | 0.1943 | [0.11-0.28] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 9p21.1 | 9 | 33128023 | NR | B4GALT1 | null | null | ENSG00000086062 | null | null | rs10813951-G | rs10813951 | 0 | 10813951 | intron_variant | 0 | 0.262743396083667 | 0.000003 | 5.522879 | (IGP76) | 0.1669 | [0.097-0.237] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 2p12 | 2 | 77019205 | NR | LRRTM4 | null | null | ENSG00000176204 | null | null | rs6547115-G | rs6547115 | 0 | 6547115 | intron_variant | 0 | 0.391438525144637 | 0.000008 | 5.09691 | (IGP76) | 0.1432 | [0.08-0.206] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 2q35 | 2 | 219999933 | NR | MIR4268 - EPHA4 | ENSG00000266518 | ENSG00000116106 | null | 93,368 | 1,418,094 | rs10198756-C | rs10198756 | 0 | 10198756 | intron_variant | 1 | 0.139068532490975 | 0.000003 | 5.522879 | (IGP77) | 0.2053 | [0.12-0.29] unit increase | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 4q34.2 | 4 | 175727181 | NR | GPM6A | null | null | ENSG00000150625 | null | null | rs9284954-C | rs9284954 | 0 | 9284954 | intron_variant | 0 | 0.444965493231047 | 0.000005 | 5.30103 | (IGP77) | 0.1418 | [0.081-0.203] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 6q25.3 | 6 | 156336708 | NR | MIR1202 - SNORD28B | ENSG00000221456 | ENSG00000212295 | null | 389,829 | 42,042 | rs12213468-G | rs12213468 | 0 | 12213468 | intron_variant | 1 | 0.655773469069871 | 0.000007 | 5.154902 | (IGP8) | 0.1455 | [0.082-0.209] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 1p31.1 | 1 | 78521617 | NR | PTGFR | null | null | ENSG00000122420 | null | null | rs672561-C | rs672561 | 0 | 672561 | intron_variant | 0 | 0.257740490431687 | 0.000009 | 5.045757 | (IGP8) | 0.1677 | [0.094-0.242] unit increase | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 7q31.1 | 7 | 114101050 | NR | FOXP2 | null | null | ENSG00000128573 | null | null | rs6466479-G | rs6466479 | 0 | 6466479 | intron_variant | 0 | 0.122643248331108 | 0.000001 | 6.30103 | (IGP17) | 0.2414 | [0.15-0.34] unit increase | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 22q13.1 | 22 | 39352849 | NR | SYNGR1 | null | null | ENSG00000100321 | null | null | rs137699-G | rs137699 | 0 | 137699 | intron_variant | 0 | 0.690710359535507 | 0.000008 | 5.09691 | (IGP18) | 0.1564 | [0.088-0.225] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 14q31.3 | 14 | 85216709 | NR | RNU6-976P - LINC02329 | ENSG00000251895 | ENSG00000258814 | null | 476,657 | 169,218 | rs1550584-C | rs1550584 | 0 | 1550584 | intron_variant | 1 | 0.469772138901295 | 0.000007 | 5.154902 | (IGP18) | 0.1382 | [0.078-0.198] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 11p12 | 11 | 41203883 | NR | LRRC4C | null | null | ENSG00000148948 | null | null | rs2862035-C | rs2862035 | 0 | 2862035 | intron_variant | 0 | 0.0246322445734703 | 0.000008 | 5.09691 | (IGP18) | 0.4382 | [0.25-0.63] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 16q23.3 | 16 | 83737891 | NR | CDH13, CEDORA, HSBP1 | null | null | ENSG00000140945, ENSG00000260788, ENSG00000230989 | null | null | rs444881-C | rs444881 | 0 | 444881 | intron_variant | 0 | 0.585534589548906 | 0.000004 | 5.39794 | (IGP18) | 0.1441 | [0.083-0.206] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 20q13.12 | 20 | 46292992 | NR | CDH22 | null | null | ENSG00000149654 | null | null | rs6065945-C | rs6065945 | 0 | 6065945 | intron_variant | 0 | 0.470163670388566 | 0.000005 | 5.30103 | (IGP18) | 0.141 | [0.081-0.201] unit increase | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 10q24.1 | 10 | 96672946 | NR | PIK3AP1 | null | null | ENSG00000155629 | null | null | rs7895244-T | rs7895244 | 0 | 7895244 | intron_variant | 0 | 0.929057661098705 | 0.000005 | 5.30103 | (IGP18) | 0.2836 | [0.16-0.41] unit increase | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2013-06-14 | 23,382,691 | Lauc G | 2013-01-31 | PLoS Genet | www.ncbi.nlm.nih.gov/pubmed/23382691 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | IgG glycosylation | 2,247 European ancestry individuals | NA | 6p21.32 | 6 | 32146738 | PRRT1 | PPT2 | null | null | ENSG00000221988 | null | null | rs9296009-T | rs9296009 | 0 | 9296009 | intergenic_variant | 0 | 0.196796488164359 | 0.000004 | 5.39794 | (IGP18) | 0.1779 | [0.1-0.25] unit decrease | Illumina [~ 2500000] (imputed) | N | serum IgG glycosylation measurement | http://www.ebi.ac.uk/efo/EFO_0005193 | GCST001848 | Genome-wide genotyping array |
2008-08-28 | 17,903,294 | Yang Q | 2007-09-19 | BMC Med Genet | www.ncbi.nlm.nih.gov/pubmed/17903294 | Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study. | Factor VII | 886 European ancestry individuals | NA | 13q34 | 13 | 113105720 | MCF2L, AB116074, AK092739, AK123267, AB002360, F7, CR603372, F10, PROZ | MCF2L - F7 | ENSG00000126217 | ENSG00000057593 | null | 5,978 | 42 | rs561241-? | rs561241 | 0 | 561241 | regulatory_region_variant | 1 | 0.12 | 0 | 15.30103 | null | null | null | Affymetrix [70897] | N | factor VII measurement | http://www.ebi.ac.uk/efo/EFO_0004619 | GCST000082 | Genome-wide genotyping array |
2008-08-28 | 17,903,294 | Yang Q | 2007-09-19 | BMC Med Genet | www.ncbi.nlm.nih.gov/pubmed/17903294 | Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study. | Factor VII | 886 European ancestry individuals | NA | 7p22.2 | 7 | 4371578 | intergenic | SDK1 - CYP3A54P | ENSG00000146555 | ENSG00000261809 | null | 102,578 | 140,381 | rs10488360-? | rs10488360 | 0 | 10488360 | intergenic_variant | 1 | 0.30 | 0.000007 | 5.154902 | null | null | null | Affymetrix [70897] | N | factor VII measurement | http://www.ebi.ac.uk/efo/EFO_0004619 | GCST000082 | Genome-wide genotyping array |
2008-08-28 | 17,903,294 | Yang Q | 2007-09-19 | BMC Med Genet | www.ncbi.nlm.nih.gov/pubmed/17903294 | Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study. | Factor VII | 886 European ancestry individuals | NA | 1p36.32 | 1 | 4255144 | intergenic | EEF1DP6 - LINC01777 | ENSG00000229280 | ENSG00000235054 | null | 79,245 | 156,883 | rs966321-? | rs966321 | 0 | 966321 | intergenic_variant | 1 | 0.47 | 0.000008 | 5.09691 | null | null | null | Affymetrix [70897] | N | factor VII measurement | http://www.ebi.ac.uk/efo/EFO_0004619 | GCST000082 | Genome-wide genotyping array |
2008-08-28 | 17,903,294 | Yang Q | 2007-09-19 | BMC Med Genet | www.ncbi.nlm.nih.gov/pubmed/17903294 | Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study. | Factor VII | 886 European ancestry individuals | NA | 3p26.1 | 3 | 7941140 | intergenic | GRM7 - LMCD1-AS1 | ENSG00000196277 | ENSG00000227110 | null | 199,607 | 10,123 | rs4591494-? | rs4591494 | 0 | 4591494 | intergenic_variant | 1 | 0.19 | 0.000009 | 5.045757 | null | null | null | Affymetrix [70897] | N | factor VII measurement | http://www.ebi.ac.uk/efo/EFO_0004619 | GCST000082 | Genome-wide genotyping array |
2008-08-28 | 17,903,294 | Yang Q | 2007-09-19 | BMC Med Genet | www.ncbi.nlm.nih.gov/pubmed/17903294 | Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study. | Hemostatic factors and hematological phenotypes | Up to 1,062 European ancestry individuals | NA | 2p16.2 | 2 | 53010182 | intergenic | MIR4431 - ASB3 | ENSG00000264975 | ENSG00000115239 | null | 307,567 | 522,490 | rs1160297-? | rs1160297 | 0 | 1160297 | intergenic_variant | 1 | 0.43 | 0.000001 | 6 | (Hgb) | null | null | Affymetrix [70897] | N | hemoglobin measurement | http://www.ebi.ac.uk/efo/EFO_0004509 | GCST000080 | Genome-wide genotyping array |
2008-08-28 | 17,903,294 | Yang Q | 2007-09-19 | BMC Med Genet | www.ncbi.nlm.nih.gov/pubmed/17903294 | Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study. | Hemostatic factors and hematological phenotypes | Up to 1,062 European ancestry individuals | NA | 8q24.13 | 8 | 121896264 | intergenic | HAS2-AS1 | null | null | ENSG00000248690 | null | null | rs7844723-? | rs7844723 | 0 | 7844723 | intron_variant | 0 | 0.45 | 0.000002 | 5.69897 | (Hgb) | null | null | Affymetrix [70897] | N | hemoglobin measurement | http://www.ebi.ac.uk/efo/EFO_0004509 | GCST000080 | Genome-wide genotyping array |
2008-08-28 | 17,903,294 | Yang Q | 2007-09-19 | BMC Med Genet | www.ncbi.nlm.nih.gov/pubmed/17903294 | Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study. | Hemostatic factors and hematological phenotypes | Up to 1,062 European ancestry individuals | NA | 11q12.1 | 11 | 56698623 | OR5AR1, OR9G1, OR9G4, OR5AP2 | TMEM230P2 - OR9G1 | ENSG00000238041 | ENSG00000174914 | null | 7,900 | 472 | rs1397048-? | rs1397048 | 0 | 1397048 | intergenic_variant | 1 | 0.4 | 0 | 7.154902 | (MCH) | null | null | Affymetrix [70897] | N | mean corpuscular hemoglobin | http://www.ebi.ac.uk/efo/EFO_0004527 | GCST000080 | Genome-wide genotyping array |
2008-08-28 | 17,903,294 | Yang Q | 2007-09-19 | BMC Med Genet | www.ncbi.nlm.nih.gov/pubmed/17903294 | Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study. | Hemostatic factors and hematological phenotypes | Up to 1,062 European ancestry individuals | NA | 11q24.1 | 11 | 122318757 | intergenic | MIR100HG | null | null | ENSG00000255248 | null | null | rs565229-? | rs565229 | 0 | 565229 | intron_variant | 0 | 0.10 | 0.000004 | 5.39794 | (pltcoll) | null | null | Affymetrix [70897] | N | platelet aggregation | http://purl.obolibrary.org/obo/GO_0070527 | GCST000080 | Genome-wide genotyping array |
2008-08-28 | 17,903,294 | Yang Q | 2007-09-19 | BMC Med Genet | www.ncbi.nlm.nih.gov/pubmed/17903294 | Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study. | Hemostatic factors and hematological phenotypes | Up to 1,062 European ancestry individuals | NA | 4p15.33 | 4 | 13792792 | intergenic | LINC01182 | null | null | ENSG00000250634 | null | null | rs10489087-? | rs10489087 | 0 | 10489087 | intron_variant | 0 | 0.13 | 0.000005 | 5.30103 | (RBCC) | null | null | Affymetrix [70897] | N | erythrocyte count | http://www.ebi.ac.uk/efo/EFO_0004305 | GCST000080 | Genome-wide genotyping array |
2008-08-28 | 17,903,294 | Yang Q | 2007-09-19 | BMC Med Genet | www.ncbi.nlm.nih.gov/pubmed/17903294 | Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study. | Hemostatic factors and hematological phenotypes | Up to 1,062 European ancestry individuals | NA | 6q25.1 | 6 | 149272784 | MAP3K7IP2 | TAB2 | null | null | ENSG00000055208 | null | null | rs727979-? | rs727979 | 0 | 727979 | intergenic_variant | 0 | 0.14 | 0.000008 | 5.09691 | (RBCC) | null | null | Affymetrix [70897] | N | erythrocyte count | http://www.ebi.ac.uk/efo/EFO_0004305 | GCST000080 | Genome-wide genotyping array |
2008-08-28 | 17,903,294 | Yang Q | 2007-09-19 | BMC Med Genet | www.ncbi.nlm.nih.gov/pubmed/17903294 | Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study. | Hemostatic factors and hematological phenotypes | Up to 1,062 European ancestry individuals | NA | 20p12.3 | 20 | 7571857 | intergenic | MIR8062 - RN7SL547P | ENSG00000278159 | ENSG00000240584 | null | 200,165 | 61,705 | rs6108011-? | rs6108011 | 0 | 6108011 | intergenic_variant | 1 | 0.28 | 0.000006 | 5.221849 | (RBCC) | null | null | Affymetrix [70897] | N | erythrocyte count | http://www.ebi.ac.uk/efo/EFO_0004305 | GCST000080 | Genome-wide genotyping array |
2008-08-28 | 17,903,294 | Yang Q | 2007-09-19 | BMC Med Genet | www.ncbi.nlm.nih.gov/pubmed/17903294 | Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study. | Hemostatic factors and hematological phenotypes | Up to 1,062 European ancestry individuals | NA | 10p11.21 | 10 | 37270652 | ANKRD30A | LINC00993 | null | null | ENSG00000235687 | null | null | rs1200821-? | rs1200821 | 0 | 1200821 | intron_variant | 0 | 0.47 | 0.000006 | 5.221849 | (MCH) | null | null | Affymetrix [70897] | N | mean corpuscular hemoglobin | http://www.ebi.ac.uk/efo/EFO_0004527 | GCST000080 | Genome-wide genotyping array |
2008-08-28 | 17,903,294 | Yang Q | 2007-09-19 | BMC Med Genet | www.ncbi.nlm.nih.gov/pubmed/17903294 | Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study. | Hemostatic factors and hematological phenotypes | Up to 1,062 European ancestry individuals | NA | 14q32.2 | 14 | 98176235 | intergenic | LINC02295 - RN7SL714P | ENSG00000258511 | ENSG00000241757 | null | 12,946 | 175,132 | rs10484128-? | rs10484128 | 0 | 10484128 | intron_variant | 1 | 0.15 | 0.000006 | 5.221849 | (pltadp) | null | null | Affymetrix [70897] | N | platelet aggregation | http://purl.obolibrary.org/obo/GO_0070527 | GCST000080 | Genome-wide genotyping array |
2008-08-28 | 17,903,294 | Yang Q | 2007-09-19 | BMC Med Genet | www.ncbi.nlm.nih.gov/pubmed/17903294 | Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study. | Hemostatic factors and hematological phenotypes | Up to 1,062 European ancestry individuals | NA | 5q21.1 | 5 | 99445399 | intergenic | LINC02113 | null | null | ENSG00000249515 | null | null | rs1829883-? | rs1829883 | 0 | 1829883 | intron_variant | 0 | 0.41 | 0.000006 | 5.221849 | (MCH) | null | null | Affymetrix [70897] | N | mean corpuscular hemoglobin | http://www.ebi.ac.uk/efo/EFO_0004527 | GCST000080 | Genome-wide genotyping array |
2008-08-28 | 17,903,294 | Yang Q | 2007-09-19 | BMC Med Genet | www.ncbi.nlm.nih.gov/pubmed/17903294 | Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study. | Hemostatic factors and hematological phenotypes | Up to 1,062 European ancestry individuals | NA | 2p16.2 | 2 | 53038991 | intergenic | MIR4431 - ASB3 | ENSG00000264975 | ENSG00000115239 | null | 336,376 | 493,681 | rs2357013-? | rs2357013 | 0 | 2357013 | intergenic_variant | 1 | 0.45 | 0.000006 | 5.221849 | (Hgb) | null | null | Affymetrix [70897] | N | hemoglobin measurement | http://www.ebi.ac.uk/efo/EFO_0004509 | GCST000080 | Genome-wide genotyping array |
2008-08-28 | 17,903,294 | Yang Q | 2007-09-19 | BMC Med Genet | www.ncbi.nlm.nih.gov/pubmed/17903294 | Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study. | Hemostatic factors and hematological phenotypes | Up to 1,062 European ancestry individuals | NA | 5q21.3 | 5 | 110161259 | intergenic | PGAM5P1 - TMEM232 | ENSG00000253224 | ENSG00000186952 | null | 275,836 | 127,974 | rs4460176-? | rs4460176 | 0 | 4460176 | intergenic_variant | 1 | 0.29 | 0.000003 | 5.522879 | (PAI-1) | null | null | Affymetrix [70897] | N | plasminogen activator inhibitor 1 measurement | http://www.ebi.ac.uk/efo/EFO_0004792 | GCST000080 | Genome-wide genotyping array |
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