accession stringlengths 6 10 | name stringlengths 6 11 | Full Name stringlengths 1 147 ⌀ | taxon stringlengths 3 46 ⌀ | sequence stringlengths 16 2.75k | function stringlengths 6 5.51k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
Q12SP7 | MURI_SHEDO | Glutamate racemase | Shewanella | MSGPILVFDSGIGGLSVLAEIRKRLPAENYCYLFDNARLPYGDLSESELIRGCVELICQQVQQVEAKIVVVACNTASTLVLPVLRQRLTIPVVGVVPAIKPAALLSKRKHIGVLATPGTVSRDYTHGLISQFAEDCQVDLFGSSELVMLAEQKAAKLPVNNQQLAKILAPIKASKLDVLVLGCTHFPMIKEELSQYLGESVLLLDSGEAIANRVASLLEPAALSEALHSGTTLHGGANSGTKGIGVIHAAYTQAITAGLNITLQEYGISDSSLIVTK | Provides the (R)-glutamate required for cell wall biosynthesis. | Q12SP7 |
Q72PA2 | SUCC_LEPIC | Succinyl-CoA synthetase subunit beta | Leptospira | MKIHEYQAKEILRRHKANVPFGVVIDKKENASKAHDEVTSKTGGSVVVVKAQIHAGGRGKGGGVKVTKTKEDAIAAVDKILGMQLITPQTGPEGKKVLKVYLEQGIDIAKEYYLSILLDRSIRKTIIMASTEGGMEIEEVAETHPEKILKIAIDPGIGLQVNQARQLAFELGLPAESHKSFQSLLAAIYEAYIKEDASLLEINPLILTKQNEIIAGDCKIDLDENALYRHADNAAFRDITEEDPLEVQASEFNLNYVKLDGNIGCMVNGAGLAMATMDIVKLAGAEPANFLDVGGGANKTTVTNGFKIILGDPNVKGIFV... | Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinat... | Q72PA2 |
Q8TII9 | VATD_METAC | V-ATPase subunit D | Methanosarcina | MAQQDVKPTRSELINLKKKIKLSESGHKLLKMKRDGLILEFFKILNEARNVRTELDAAYEKSTEKINLASAVNGMVAVKSTAFTAKEYPEIQLSGHNIMGVVVPKISSTGVRKPLYERGYGIIGTNSYIDETADAYEELVEKIIAAAELETTMKRLLDEIEKTKRRVNALEFKVIPELIATMKYIRFMLEEMERENTFRLKRVKARMKN | Produces ATP from ADP in the presence of a proton gradient across the membrane. | Q8TII9 |
A6WP56 | SYM_SHEB8 | Methionyl-tRNA synthetase | Shewanella | MATSQRKILVTSALPYANGPIHLGHMLEYIQTDIWSRYQKLRGHECHYICADDAHGTPIMLKAQQLGIAPEDMIAQVNKEHQQDFADFNVAFDNYHSTHSEENRLMASDIYLKLRDNGYIKSKSISQLFDPEKSMFLPDRFVKGTCPKCKSPDQYGDNCDSCGATYSPTELINPKSAVSGATPVMKDTEHFFFDLPAFEGMLKEWTRSGALQVEMANKLDEWFEQGLQQWDITRDAPYFGFEIPDAPGKYFYVWLDAPIGYMGSFKNLCAKRPELSFDEFWGKDSTAEVYHFIGKDIVYFHSLFWPAMLHGSGYRQPNSV... | Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | A6WP56 |
Q2JII9 | GLMU_SYNJB | Glucosamine-1-phosphate N-acetyltransferase | unclassified Synechococcus | MAERELSVAILAAGKGTRMRSQLPKVLHKLGSLSLIERLLRTVLTLKPHRCLVVVGYEQEQVRQALREYPVEFVEQAQQLGTGHAVQQLLPVLGGFQGDLLVINGDVPLLRAETLQALVERHRQVNPEVTLLSAQVADPYGYGRVFCDAQQRVLELVEERDCTPAQRQNRRINSGVYCFHWPALAQVLPHLNRNNAQQEYYLTDAVKRVGKAIALDVADPQEIVGVNDRRQLAQAYQILQDRLKEAWMEAGVTFVDPDSSSLEETVELAPDVVIEPQTHLRGVCRIGPGTRLGPGSWIESSEIGSGCHILYSVVSHSRIG... | Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted ... | Q2JII9 |
A1UFB6 | APT_MYCSK | Adenine phosphoribosyltransferase | unclassified Mycobacterium | MTDISKVIASLMREVPDFPEPGIQFKDLTPLLADAEGLMAVTDALAATAEGADLVAGIDARGFLLGAAVALRLGTGVLAVRKGGKLPPPVHSQTYNLEYGSATLEIPADGLDIAGRSVVIIDDVLATGGTVAATHRLLTSGGATVLHAAVVLELTALGGREVVQPLSVSSLYTV | Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | A1UFB6 |
B0U1N1 | ACCA_XYLFM | Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha | Xylella | MNPNYLDFEQPIADLEAKIQELRTASAGPSVNVDTEVRALENKLRLRTAQIFRNLSAWQISQLARHPRRPYTLDYISVVCDEFQELAGDRTLADDKAIVGGLARIGHRPVMLIGHQKGRDNKERLMRNFGMPKPEGYRKALRLMKLAERFGLPLLTFIDTMGAWPGIDAEERNQSEAIATNLIEMAELKIPVICTVIGEGGSGGALAIGIGDRTLMLEYSTYSVITPEGCASILWKDAAKASDAAEQLNLTARRLKEFGLIDKVIREPIGGAHRNPQQMANRLKAVLLNELEALDKVPLVTLLNQRHKRLRTYGAYENH | Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | B0U1N1 |
A0JM41 | MYP0_XENTR | Myelin protein zero | Silurana | MESSGLRAPCSLLVLLSALVLPPTLAIEVYTDREVYGTVGSRVTLSCSFWSSEWISDDVSVTWHYQPDHSREMYSIFHYAKGQPSIDAGVFKDRIEWVGSPKWKDASIVLHNLELIDNGTFTCDVKNPPDVVGKSSYVHLQVQEKGAARAGLVLGIIIAVALALVIVVTILILLIRYCWLRRQVRVQRELSALERGKLHKAKDSSKRSSRQTPILYAMLDQTRGKASEKKGKGGIGDSRKDRK | Creation of an extracellular membrane face which guides the wrapping process and ultimately compacts adjacent lamellae. | A0JM41 |
O84711 | CLPX_CHLTR | ATP-dependent Clp protease ATP-binding subunit ClpX | Chlamydia | MTKKNLAVCSFCGRSEKDVEKLIAGPSVYICDYCIKLCSGILDKTPAPATQEIATSSTSSPTSLRVLTPKEIKRHIDSYVIGQERAKKTISVAVYNHYKRIRALMQDKQVSYGKSNVLLLGPTGSGKTLIAKTLAKILDVPFTIADATTLTEAGYVGEDVENIVLRLLQAADYDVARAERGIIYIDEIDKIGRTTANVSITRDVSGEGVQQALLKIIEGTVANIPPKGGRKHPNQEYIRVNTENILFIVGGAFVNLDKIIAKRLGRTTIGFSEETDLAVTNRDHLLAKVETEDLIAFGMIPEFIGRFNCVVNCEELTLDE... | ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | O84711 |
Q8PTQ6 | NIKR3_METMA | Putative nickel-responsive regulator 3 | Methanosarcina | MGKKLMRIGISLPGELLDKFDKTLMKRGYSSRSEGIRDAIRTYNQHYEWMKQIRGSRSATISIVYDCSKKGVTSTLAEIQHEYVDMISSSVHFHMEEDLCFEVIILRGEGEQIVDLAQRILSIKGVKHLRLTTVPEEKNE | Transcriptional regulator. | Q8PTQ6 |
P25553 | ALDA_ECOLI | Glycolaldehyde dehydrogenase | Escherichia | MSVPVQHPMYIDGQFVTWRGDAWIDVVNPATEAVISRIPDGQAEDARKAIDAAERAQPEWEALPAIERASWLRKISAGIRERASEISALIVEEGGKIQQLAEVEVAFTADYIDYMAEWARRYEGEIIQSDRPGENILLFKRALGVTTGILPWNFPFFLIARKMAPALLTGNTIVIKPSEFTPNNAIAFAKIVDEIGLPRGVFNLVLGRGETVGQELAGNPKVAMVSMTGSVSAGEKIMATAAKNITKVCLELGGKAPAIVMDDADLELAVKAIVDSRVINSGQVCNCAERVYVQKGIYDQFVNRLGEAMQAVQFGNPAER... | Catalyzes the irreversible oxidation of L-lactaldehyde to L-lactate . Also shows high activity with glycolaldehyde and L-glyceraldehyde . Has weaker activity with various aldehydes such as methylglyoxal, propionaldehyde or benzaldehyde . Involved in the degradation of lactaldehyde produced during metabolism of L-fucose... | P25553 |
B0UYF2 | S7A14_DANRE | Solute carrier family 7 member 14 | Danio | MSGLFAKLDPRRVQWGANWFAFRSRVLRTKPVESMLETSGGTGAHGTKLARVLSTVDLVSLGVGSCVGTGMYVVSGLVAKEMAGPGVIVSFIIAAVASILSGVCYAEFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLILEYLIGTAAGASALSSMFDSLANHSISGFMINHIGTLNGLGKGEQSYPDILALVIGILVTVIVALGVKNSVGFNNVLNVINLVVWVFIMIAGLFFVSGSNWDEGRFLPYGWSGVMQGAATCFYAFIGFDIIATTGEEAKSPNTSIPYAITASLVTCLTAYVSVSVILTLMVPYTEIDSDA... | May be involved in arginine transport. | B0UYF2 |
A7N128 | HEM6_VIBC1 | Oxygen-dependent coproporphyrinogen-III oxidase | Vibrio | MSAIDKHAVKQFLMSLQDSICQQLEQEDGKAVFVEDAWQREKGERLGGGGRTRVLRDGHIFEQGGVNFSHVEGNEMPASATAHRPELAGRRFEAMGVSLVIHPKNPYVPTSHANVRFFIAEKDGEDPIWWFGGGFDLTPFYPFDEDCQSWHDTAKQLCAPFGDEVYPEHKAWCDKYFFLPHRNETRGVGGLFFDDLNQWEFDKCFDYIKAVGEGYCQAYLPIVSRRKDIEFGEREREFQLYRRGRYVEFNLVYDRGTLFGLQSGGRTESILMSMPPLARWEYSYEPQTGSPEAELYERYLTPREW | Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX. | A7N128 |
O26911 | COFH_METTH | FO synthase subunit 2 | Methanothermobacter | MNIKTRTKKILQKAMDEPITKEEALYLMGVTGRDLQALMIAADMVREAEAGDRITYIENWNINFTNICSGQCGFCAFKRDAADGDSYYLETERILEIAAEAIEKGARELCIQGGLYPGLDTYFYEDLIRAIKSEFPDVHLHSFSPMEVYYGAQNAELTVEEALKILKRAGLGSMPGTAAEILDDDVRAVICPTKLSTGEWVEVIETAHRVGIPTTCTMMYGHIDGPEHRVEHMDILRRIQEKTGGFTEFVPLPFMHPHAPIYREGLAMPGATGADDLKVYAISRLMFRGLIENIQASWVKLGFKFAQVALLSGANDIGGT... | Catalyzes the radical-mediated synthesis of 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine. | O26911 |
A9B6A7 | TATA_HERA2 | Sec-independent protein translocase protein TatA | Herpetosiphon | MAGLGVTELLIILAIVIVLFGASRIGDLGGAMGRGIREFRRGVRDEDATAPTDASKNESK | Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | A9B6A7 |
Q0SIG0 | PSA_RHOJR | Proteasome core protein PrcA | Rhodococcus | MTMPYYASAEQIMRDRSELARKGIARGRSVVVLTFRDGVLFVAENPSTALHKVSELYDRLGFAAVGKYNEFENLRRAGIVHADMRGYSYDRRDVTGRSLANAYAQTLGTIFTEQPKPYEVEICVAEVGRVGSPKAPQLYRITYDGSIVDEQHFVVMGGTTEPIATAMRESYRADLDLEAAVGIAVNALRQGGAGEGEKRNVDVASLEVAVLDQSRPRRAFRRITGPALEQLIPAEPAPASEPAPESKPDTETKPADPQD | Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | Q0SIG0 |
B0SYU4 | HUTU_CAUSK | Imidazolonepropionate hydrolase | unclassified Caulobacter | MTRLDNTRVIRPATGTELTAKSWLTEAPLRMLMNNLHPDVAERPEELVVYGGIGRAARDWESYDKIVETLRRLEDDETLLVQSGKPVGVFKTHPDAPRVLIANSNLVPRWATWEHFNELDRKGLAMYGQMTAGSWIYIGAQGIVQGTYETFVEMGRQHHGGDLAGKWLLTAGLGGMGGAQPLAAVMAGASCLAIECQPSRIEMRLRTGYLDKATERLDEALAWIAEANAAKAPVSVGLLGNAAELLPAMFAAGVRPDLLTDQTSAHDPINGYLPAGWTLDQWATAKEREPETVNRAARASMAVHVQAMLDFQAAGVPTVD... | Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate. | B0SYU4 |
B3DRY2 | APT_BIFLD | Adenine phosphoribosyltransferase | Bifidobacterium | MAQSDITIDALSKVGQQDAEYLVSLVRSVPGFPKEGIIFRDFMPVLADPKGLKILLKALEEALPVSPSEFDSIAGLESRGFLFGPAMAAHLGKGFIAVRKAGKLPPETIGESYDLEYGTASVEIETDAVQAGKRVLIVDDLIATGGTAKAATDLIEKAGGTVVGFSFVMRLDGLDGLDKLDGKPSSSLIAMPA | Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | B3DRY2 |
B9M5V2 | FPG_GEODF | DNA-(apurinic or apyrimidinic site) lyase MutM | Geotalea | MPELPEVETIRRAVGPQVRGKRIIHTNVRATKLRHPLPPELDRLLVGQLIVAMDRRGKYLLLRCKGGTIIFHLGMTGMLYLVKASSPHGKHDHLDLVLDGSYILRFTDPRRFGTIIWTDNDPLQHPLLVAHGPEPLEAEFSASYLYLKRHRRKIPIKQLIMDSRVVAGIGNIYANESLFRAGIAPQTSASDLSPDKDLLLVDAIKGVLTDAVEAGTSNIESALTGERPQGYFPYEFSIYGKKGRPCPKCGSAIRMMRLGGRSTFFCPLCQK | Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. ... | B9M5V2 |
B7KL75 | GLMM_GLOC7 | Phosphoglucosamine mutase | Gloeothece citriformis | MVTSLYRNGNGRLNSYTQDTANLGVVNQLCPLPKTPLFGTDGIRGKVGELLNASLALDLGFCAAQVLKATMPTPGPIIIGQDSRNSSDMLTTAITAGLTSAGVEVWQIGLCPTPCVAYLARNTEAMGGIMISASHNPPEDNGIKFFDHQGLKLSKGLAQQVEDLLRNTLESNSQRESSLSWGKYYHRRELIEQYLQQLSLSIPTDVNLEGMRIVLDLAWGAAVEIAPQVFKSLGAEVICLHDQPDGDRINVNCGSTHLNLLQQAVKEFGADLGVAFDGDADRVLAVDSEGRVVDGDYILYFWGQTLKAQDKLPNNLIIAT... | Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. | B7KL75 |
A9M8R8 | DAPF_BRUC2 | PLP-independent amino acid racemase | Brucella | MATKAAFARMNGLGNQIIVADMRGRADSITSAAAIRLASDSETAFDQIMAIHDPRTPGTDYYIAIINCDGTQAQACGNGTRCVVQALAAETGRHAFTFETRAGILTATEHDDGLISVDMGTPRFDWQDIPLAQAVADTRKIELQVGPADAPVLHSPSIASMGNPHAVFWVDKDVWSYELDKFGPLLENHPIFPERANISIAHVTSSDTIDLRTWERGAGLTRACGSAACAAAVSAARTGRTGRKVTVNVPGGPLLIEWRDDDHVMMTGPAEWEFSGTFDPATGEWSRDTQGLQGSGNADRGTA | Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan. | A9M8R8 |
Q1JDG6 | METN_STRPB | Methionine import ATP-binding protein MetN | Streptococcus | MNEAIIQLDHIDITFRQKKRVIEAVKDVTVHINQGDIYGIVGYSGAGKSTLVRVINLLQAPTNGKITVDGDVTFDQGKVQLSANALRQKRRDIGMIFQHFNLMAQKTAKENVAFALRHSSLSKTEKEHKVIELLELVGLSERADNYPAQLSGGQKQRVAIARALANDPKILISDEATSALDPKTTKQILALLQELNRKLGLTIVMITHEMQIVKDICNRVAVMQNGVLIEEGSVLDIFSNPKEALTQEFITTATGIDEALEKINQQDIVKHLPANALLAQLKYAGTSTDEPLLNSIYRQFEVTANILYGNIEILDHIPVG... | Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | Q1JDG6 |
Q9RGS4 | YIDC_STACT | Membrane protein YidC | Staphylococcus | MKKKALLPLLLGIMVFLAGCDYSKPENRTGFFYNTFVKNMDNIIHWLGASFNNDYGLAIIVLVLAIRIIVLPFMLSNYKNSHMMREKMIIAKPDMDAVKEKVQRARTQEDKMAANQEMMEVYKKYDMNPMQSMLGCLPMLIQMPIIMGLFFVLKYPSPGGITEHSHFLWFNLAKPDIWITVIAGVLYFLQAYVSTFSMPPEQKQMSYMMMIISPIMIIWVSLSSAAALGLYWSVSAAFLIVQTYIANAYYSKKAKEEVAPMIAAYEKEHGGSGNSKGAKVVSKKNKKKK | Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. | Q9RGS4 |
Q9SLP9 | CAS1_LUFAE | Cycloartenol synthase | Luffa | MWQLKIGADTVPADPSNAGGWLSSLNNHVGRQVWHFHPELGTPEDLQQIQHARQRFSDHRFEKKHSADLLMRMQFAKNNSSFVNLPQIKVKDKEDVTEEAVSRTLRRAINFYSTIQGDDGHWPGDYGGPMFLIPGLVITLSITGALNAVLSTEHQREICRYLYNHQNKDGGWGLHIEGPSTMFGSVLNYVSLRLLGEEAEDGQGAVDKARKWILDHGGASAITSWGKMWLSVLGVYEWAGNNPLPPELWLLPYLLPFHPGRMWCHCRMVYLPMCYLYGKRFVGPITPIIRSLRKELYLVPYHEVDWNKARNECAKEDLYY... | Oxidosqualene cyclase involved in the biosynthesis of cycloartenol. | Q9SLP9 |
A4G064 | HMD_METM5 | N(5),N(10)-methenyltetrahydromethanopterin hydrogenase | Methanococcus | MKVAILGAGCYRTHAASGITNFSRAAQVAKEVGIPEITMTHSTITMGAELLHLIPEITEVVVSDPCFAEEPGIVVLDQFDYKTVMEAHLAGDAEKVMPEIREAVKAKAKETPKPPKGCIHFVHPETIGLKVTASDVEAVKNADIVITWLPKGGSQPAIIEKFVGAIKKGAIVTHACTIPTPKFAKIFKDMGRDDLNIIAYHPGAVPEMKGQAFLSEGLADAEKVEEFYCMAKTARGEAFKMPANLISPVCDMGSAVTAPVYAGILAYRDAVTQILGAPADFAQMMADEAITQLLELMRSEGIKNMEDKLNPKALTGTADS... | Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT. | A4G064 |
A3DIZ5 | RPOC_ACET2 | Transcriptase subunit beta' | Acetivibrio | MFELNNFDSIRIGLASPEKIREWSRGEVKKPETINYRTLKPERDGLFCERIFGPQKDWECHCGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHIELAAPVSHIWYFKGIPSRMGLLLDMSPRALEKILYFAAYVVIDPGQTPLSKKQILSEKEYRDSLEKFGPKFRAGMGAEAVRELLQEINLDELSAELREEIKQSTGQKRVRAIKRLEVVEAFRQSQNKPEWMILDVIPVIPPELRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLDLGAPDIIVRNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSDML... | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | A3DIZ5 |
Q0WQD2 | GAUT3_ARATH | Probable galacturonosyltransferase 3 | Arabidopsis | MTTFSTCAAFLSLVVVLHAVHVGGAILESQAPHRELKAYRPLQDNNLQEVYASSAAAVHYDPDLKDVNIVATYSDHYGNIRLGRVKMGDLSPSWVLENPAYQVSRKTKGSQLVIPRDSFQNDTGMEDNASHSTTNQTDESENQFPNVDFASPAKLKRQILRQERRGQRTLELIRQEKETDEQMQEAAIQKSMSFENSVIGKYSIWRRDYESPNADAILKLMRDQIIMAKAYANIAKSKNVTNLYVFLMQQCGENKRVIGKATSDADLPSSALDQAKAMGHALSLAKDELYDCHELAKKFRAILQSTERKVDGLKKKGTFL... | May be involved in pectin and/or xylans biosynthesis in cell walls. | Q0WQD2 |
P40312 | CYB5_YEAST | Cytochrome b5 | Saccharomyces | MPKVYSYQEVAEHNGPENFWIIIDDKVYDVSQFKDEHPGGDEIIMDLGGQDATESFVDIGHSDEALRLLKGLYIGDVDKTSERVSVEKVSTSENQSKGSGTLVVILAILMLGVAYYLLNE | Membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases. It plays a role in fatty-acid desaturation and is also involved in several steps of the sterol biosynthesis pathway, particularly in the 4-demethylation of the 4,4'-dimethyl zymosterol. | P40312 |
Q39024 | MPK4_ARATH | Mitogen-activated protein kinase 4 | Arabidopsis | MSAESCFGSSGDQSSSKGVATHGGSYVQYNVYGNLFEVSRKYVPPLRPIGRGAYGIVCAATNSETGEEVAIKKIGNAFDNIIDAKRTLREIKLLKHMDHENVIAVKDIIKPPQRENFNDVYIVYELMDTDLHQIIRSNQPLTDDHCRFFLYQLLRGLKYVHSANVLHRDLKPSNLLLNANCDLKLGDFGLARTKSETDFMTEYVVTRWYRAPELLLNCSEYTAAIDIWSVGCILGETMTREPLFPGKDYVHQLRLITELIGSPDDSSLGFLRSDNARRYVRQLPQYPRQNFAARFPNMSAGAVDLLEKMLVFDPSRRITV... | The ANPs-MKK6-MPK4 module is involved in the regulation of plant cytokinesis during meiosis and mitosis. Essential to promote the progression of cytokinesis and for cellularization (formation of the cell plate) during male-specific meiosis. Involved in cortical microtubules organization and stabilization by regulating ... | Q39024 |
Q824N9 | RL5_CHLCV | 50S ribosomal protein L5 | Chlamydia | MSRLKKLYTEEIRKSLQEKFGYGNTMQIPVLRKIVISMGLAEAAKDKNLFQAHLEELSMISGQKPLVTKARNSIAGFKLREGQGIGAKVTLRGQRMYDFMDRFCNIVSPRIRDFRGFSMKGDGRGCYSLGLDDQQIFPEIDLDRVKRTQGMNITWVTTAQTDVECTTLLELMGLRFKKAQ | This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement... | Q824N9 |
Q5WDS1 | TYSY_ALKCK | Thymidylate synthase | Alkalihalobacillus | MEQYLQLCEHVLQNGSPKSDRTGTGTISVFGYQMRFDLEKGFPIVTTKKLHMRSIIHELLWFLKGDTNIRYLQENGVRIWNEWADENGDLGPVYGKQWRSWEGANGKTVDQITEVVEQIKTNPNSRRLIVNAWNVAEIEEMALAPCHCLFQFYVNDGKLSCQLYQRSADIFLGVPFNISSYALLTMMMAQVCGLKPGEFIHTFGDAHLYNNHIEQTKLQLTRKPKQLPTMHINPEVTDLFAFTYDDFELKHYDPYPHIKAEVSV | Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracell... | Q5WDS1 |
Q4FVB6 | PAND_PSYA2 | Aspartate 1-decarboxylase alpha chain | Psychrobacter | MLLNMLKCKLHRARVTHAELHYEGSCGIDGDLLDLAGLRENESIDIYNVTNGKRFRTYAIRAEAGSGIISLNGAAAHMADLGDIVIICAYAHFDEVEASTYQPRLVYCNEDNTVKDTANIIPVQVA | Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | Q4FVB6 |
A0Q845 | HEM1_FRATN | Glutamyl-tRNA reductase | Francisella | MALISLAIDYKKSPIEVRSEFALSGLDVSMLYRSILAIDNVVHAVILSTCNRTEVYLEISDLRVVDDILVWWQGYVRNPNYKIKDYFKLRQGTEVIMHLMKLACGLESMVLGEPQILGQVKDSYTLSKKNHAIGKELDRVFQKVFATAKRVRSETRIGYCPVSVAFSAITLAKRQLDNICSKNVLIIGAGQTGELLFRHVTALAPKQIMLANRTIEKAQKITSAFRNASAHYLSELPQLIKKADIIIAAVNVSEYIVTCKDVGDKPRVFIDISIPQALDPKLGELEQNVYYCVDDINAVIEDNKDKRKYESSKAQKIIVK... | Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | A0Q845 |
A1BF85 | COAD_CHLPD | Pantetheine-phosphate adenylyltransferase | Chlorobium | MKRKAIYPGTFDPFTNGHLDVLDRALNIFDEVEVVIGENSQKKTLFTVNERLEMIREIVIEFPGVTVAVLHDGLLANYARQVEARAIVRGVRQVKDFEYEFQMSLLNRHLYPEVTTVFLMPNVKYTYVASSIIREVAMLGGDVSKFVHPCVLAMLHKKLQENKKSNS | Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. | A1BF85 |
Q13U01 | SECA_PARXL | Protein translocase subunit SecA | Paraburkholderia | MTTGFLQKIFGSRNQRLVKQYQKTVAAINALEPQIEQLTDDQLRGKTGEFRQRVASGESLDKLLPEAFAVCREASKRVLKMRHFDVQLIGGMVLHYGKIGEMRTGEGKTLVATLPVYLNALSGRGVHVVTVNDYLAQRDAEWMARLYNFLGLSVGINLSQMDHAAKQEAYAADITYGTNNEFGFDYLRDNMVYETDARVQRALNFAVVDEVDSILIDEARTPLIISGQAEDHTELYVRMNALPPLLERQIGEEKADGTGVEKPGDYTLDEKGRQVFLTESGHEKAERLLSEWGLIGEGESLYAPQNITLMHHVYAALRAH... | Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor drivin... | Q13U01 |
Q3ZYP4 | SYE_DEHMC | Glutamyl-tRNA synthetase | Dehalococcoides | MTNEVRVRYAPSPTGYPHLGNIRTAMFNWLFARHNGGKFIVRIEDTDRERYVEGAVESILESLNWLGLDWDEGPDKGGDYGPYYQSERLPLYRKAAEKLVAEGKAYYCHCSSEKLDKMREDQIARKEPPGYDRCCRDMGLGQKEGAVIRFKIPLDGQTAFTDLIRGEVTFDNAKQDDFVILKSDGFPTYHLASVVDDHAMQISHVLRAEEWLPSTPKHLMLYKALGYTPPLYAHLPMILGPDRSKLSKRHGATSTIEYKQAGYLPETMVNFLSLLGWAYDDKTELFSREQLIEYFCLEKVSKTAAIFNYEKLDWMNGMYI... | Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | Q3ZYP4 |
P67023 | SYE_STRP1 | Glutamyl-tRNA synthetase | Streptococcus | MSKPIRVRYAPSPTGLLHIGNARTALFNYLYARRHGGTFIIRIEDTDRKRHVEDGERSQLENLKWLGMDWDESPETHENYRQSERLALYQQYIDQLLAEGKAYKSYVTEEELAAERERQEAAGETPRYINEFIGMSADEKAKYIAEREAAGIVPTVRLAVNESGIYKWTDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVVDDHDMQISHVIRGDDHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYMPEAVFNFIALLGWNPGGEEEIFSREQLIALFDENRLSKSPAAFD... | Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | P67023 |
Q48F57 | GLND_PSE14 | [Protein-PII]-UMP uridylyl-removing enzyme | Pseudomonas | MPQVDPDLFDRGQFQAELALKASPIAAFKKAIRRAKDVLDDRFKSGRDIRRLIEDRAWFVDNILQKAWDQFEWSEDADIALLAVGGYGRGELHPYSDIDLLILLDSDDHEVFREPIERFLTLLWDIGLEVGQSVRSVNECAQEGRADLTVITNLMESRTIAGPEHLRQRMLEVTSTEHMWPSKEFFLAKHAEQKKRHHKYNDTEYNLEPNVKGSPGGLRDIQTILWVARRQYGTLNLHALAGEGFLLGSENALLASSQEFLWKVRYALHMLAGRSEDRLLFDYQVRIAGLLGYEDSDAKLAIERFMQKYYRVVMSIAELS... | Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine ... | Q48F57 |
A3MSF2 | HIS3_PYRCJ | Phosphoribosyl-AMP cyclohydrolase | Pyrobaculum | MDAVPLATPEEAWRIAKSLNYRHIGGTVVAVVQDVETGEVLMVGHMDPVAVVLTLTTGLAHYYSTSRKRIWLKGETSGHYQIVKEFRTDCDGDAVVLKVVQIGAACHTGARSCFSSPASFKIRLNRDA | Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | A3MSF2 |
Q8VHL5 | CRGN_MOUSE | Gamma-N-crystallin | Mus | MAQRSGKITLYEGKHFTGRKLEVFGDCDNFQDQGFMNRVNSIRVESGAWVCFDHPDFRGQQFILEHGDYPEFFRWNGHNDHMGSCRPVGMHGEHFRIDIFEGCNFTGQCLEFVEDCPFLQSRGWAKSCVNAIKVYGDGAWVLYEEPNYRGRMYVLERGDYRCFSDWGAHSARVQSLRRVLNFF | Crystallins are the dominant structural components of the vertebrate eye lens (Probable). Also plays an important role for integrity and function of auditory nuclei . | Q8VHL5 |
A7IEC3 | BIOB_XANP2 | Biotin synthase | Xanthobacter | MTTSTGTTTGTGTARAAEGSLLRSDWTEAEARALYDLPFPELMFRAQSVHRRHFDPTTVETATLLSIKTGGCAEDCGYCSQSAHHETGLKATKLMGVEEVLSQAQKAKDGGATRFCMGAAWRSPKDRDLDAVCAMISGVKAMGLEACVTLGMLTPDQVTRLGAAGLDYYNHNIDTSPAFYPEIVTTRTMDDRLDTLASVRAGGIRLCTGGIVGMGESVDDRIAMLLVLATLDPHPESVPINMWNEIEGTPVMGKADKPDPIAFVRLIALARLLMPQSIVRLSAGRDAMSDEMQALCFLAGANSIFTGDVLLTTANPERDK... | Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism. | A7IEC3 |
P26905 | DPPD_BACSU | Dipeptide transport ATP-binding protein DppD | Bacillus | MEKVLSVQNLHVSFTTYGGTVQAVRGVSFDLYKGETFAIVGESGCGKSVTSQSIMGLLPPYSAKVTDGRILFKNKDLCRLSDKEMRGIRGADISMIFQDPMTALNPTLTVGDQLGEALLRHKKMSKKAARKEVLSMLSLVGIPDPGERLKQYPHQFSGGMRQRIVIAMALICEPDILIADEPTTALDVTIQAQILELFKEIQRKTDVSVILITHDLGVVAQVADRVAVMYAGKMAEIGTRKDIFYQPQHPYTKGLLGSVPRLDLNGAELTPIDGTPPDLFSPPPGCPFAARCPNRMVVCDRVYPGQTIRSDSHTVNCWLQ... | Probably part of the ABC transporter DppBCDE involved in dipeptide transport (Probable). Responsible for energy coupling to the transport system (Probable). | P26905 |
O35775 | SYCN_RAT | Proximal small intestine-specific protein 9 | Rattus | MSPLCLLLLALALVAVPGARGACPVPADLKKSDGTRTCARLYENSDPYYDNCCQGPELSVDPGTDLPYLPSDWSNSASSLVVAQRCELTVWSLPGKRGKTRKFSTGSYPRLEEYRKGIFGTWAKSISGLYCKCY | Functions in exocytosis in pancreatic acinar cells regulating the fusion of zymogen granules with each other. May have a pore-forming activity on membranes and regulate exocytosis in other exocrine tissues. | O35775 |
O29346 | SYG_ARCFU | Glycyl-tRNA synthetase | Archaeoglobus | MHMSEIMEMLIRRGFLWQSFEIYGGMAGFIDYAPLGNNLRRKIENIWRKYFVINERAAEIDTPTIGIEEVFIASGHATSFTDVAIECENCGRVYRADHYVKEKLGIEVDETVEAVKEVMEVYDLKCECGGRFKDPAPMNLMFSTTIGPGKGKKGYLRPETAQGMFVDFKRLANFFREKLPFGVAQIGRAYRNEISPRQGVIRLREFNQAELEFFVHPGEKKHPHFSLYAKDVVKLVDKFDSQHEITLEEAVEKGIIANQILAYFIGKTRRFLLEIGIKDEKLRFRQHKDVERAHYATDCWDAEVLTSYGWIEVVGIADRT... | Catalyzes the attachment of glycine to tRNA(Gly). | O29346 |
Q9KNK2 | HSLO_VIBCH | Heat shock protein 33 homolog | Vibrio | MANNMLHRYLFKDLSVRGELVQLDDTYQQMISSQEYPAAVQHLIGELLVATSLLTATLKFEGSITLQLQGNGPVSLVVINGDNNQQVRGVARWKGDIADDASLHDMLGKGHLVITIEPKQGERYQGVVGLEGDTLAQVLEGYFERSEQLKTRLWIRVGKHDGKACAAGMLLQIVPDGKGSAEDFEHLEQLTNTIKDEELFALPAEELLYRLYNQETVQLFTPQQISFRCGCSRERSAAAIVTVAREEINDILAQDGAVALHCDYCGTTYSFDSAQVAELYAPSSANGSTLH | Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress. | Q9KNK2 |
P28418 | RBL_GEUQU | Ribulose bisphosphate carboxylase large chain | Geum | VGFKAGVKEYKLTYYTPDYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVPGEESQFIAYVAYPLDLFEEGSVTNLFTSIVGNVFGFKALRALRLEDLRIPPAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEALFKAQAETGEIKGHYLNATAGTCEEMMKRAIFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRMSGGDHIHAGT... | RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site. | P28418 |
Q3KLB0 | ENO_CHLTA | 2-phosphoglycerate dehydratase | Chlamydia | MFDVVISDIEAREILDSRGYPTLCVKVITNTGTFGEACVPSGASTGIKEALELRDKDPKRYQGKGVLQAISNVEKVLMPALQGFSVFDQITADAIMIDADGTPNKEKLGANAILGVSLALAKAAANTLQRPLYRYLGGSFSHVLPCPMMNLINGGMHATNGLQFQEFMIRPISAPSLTEAVRMGAEVFNALKKILQNRQLATGVGDEGGFAPNLASNAEALDLLLTAIETAGFTPREDISLALDCAASSFYNTQDKTYDGKSYADQVGILAELCEHYPIDSIEDGLAEEDFEGWKLLSETLGDRVQLVGDDLFVTNSALI... | Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | Q3KLB0 |
B2HWM9 | OBG_ACIBC | GTP-binding protein Obg | Acinetobacter calcoaceticus/baumannii complex | MRFVDEAVITVEAGDGGNGVASFRREKFVPFGGPDGGDGGRGGSIYIQADDDTSTLVDYRYTRKFRAERGKNGAGANCTGRGGEDVVLKVPVGTTIVDTDSGDIIGDLVEDGQRVMVASGGEGGLGNTHFKSSTNRAPRKCTTGTKGEFREIRLELKVLADVGLLGMPNAGKSTFIRAVSAAKPKVADYPFTTMVPNLGVVDADRHRSFVMADIPGLIEGAAEGAGLGIRFLKHLARTRILLHIIDVQPIDGSDPAHNAKAIMNELAKFSPTLAKLPIVLVLNKLDQIAEESREEWCQHILDELQWTGPVFKTSGLLEEG... | An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. | B2HWM9 |
Q02QY1 | RNFD_PSEAB | Rnf electron transport complex subunit D | Pseudomonas | MALPRPTSPHARGSNRTPAIMRLVLGACVPGLLTLTWLYGPGTLLNLAWASLVALACEAAMLALRKRPPGVFLKDGSALVTALLLAVALPPYAPWWLTLVATFFALVFGKHLYGGLGQNPFNPAMLGYVVALVSFPLEMTRWPSPDSALGLPDSLREFLGLATRPDAWAHATALDVLKTDRSLTVDELFAGNPAFGHLGSAGSEWVNLAFLLGGLFLLWRRLFTWHAPLGMLAGLFAMSLLFWNGSGSDSHGSPLFHLFSGATMLGAFFIVTDPVSGATSNRGRLVFGLGVGVLTYVIRAWGGYPDGVAFAVLLMNLAAP... | Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. | Q02QY1 |
Q38YR8 | CH10_LATSS | Chaperonin-10 | Latilactobacillus | MLKPLEDRVVIAVKDEAEQTVGGIVIASNAKQKPQTGKVVAVGAGAMTSDGQRIPLDVKENDEVIYDKYAGSEVEYEGQQYLVLHAKDIIAIIE | Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of ... | Q38YR8 |
Q8CPM1 | COXX_STAES | Heme O synthase | Staphylococcus | MNKDQTLSHTTGRVSFKELQQIIKMGLVQGNLIPAFAGAWLAIVMTNHSFLSSIPQILLMLVGSTLIMGGACALNNYYDQDIDRIMPSKQGRPTVNDRISDRNLLMLSFGMMLIGEACLFLLNIPSGVLGLIGIVGYVSYYSIWSKRHTTWNTVVGSFPGAVPPLIGWVAIDGSLSLAAVALFLVVFCWQPIHFYALAIKRSDEYALANIPMLPSVKGFKRTRVSMFIWLVLLLPLPFLLSNLGVTFVVIATLLNLGWLALGFTTFRKESNQTKWATQMFVYSLNYLVVFFALVVVVSLIKMI | Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. | Q8CPM1 |
Q9UWW8 | VATB_SACS2 | V-ATPase subunit B | Saccharolobus | MLSVREFSNISMIKGPLVYVQGVTDASYNELVEIEMPNGERRRGLVIDSQMGIAIVQVFEGTTGVSPTGTKIRMLGRGLEVKISEEMLGRIFNPLGDSLDNGPPVIKGEKRDINGSPLNPAAREYPEEFIQTGISAIDGLNALLRGQKLPIFSGSGLPANMLAAQIAKQATVRGEESNFAVVFAAIGARYDDALFFRKFFEETGAINRVAMIVSLANEPPVMKTLTPKTALTLAEYLAFEQDMHVLAILIDMTNYCEALREISAAREEVPGRGGYPGYMYTDLATIYERAGKVIGKKGSITQMPILTMPNDDITHPIPDL... | Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit. | Q9UWW8 |
C1DFV8 | DEF_AZOVD | Polypeptide deformylase | Azotobacter | MAILTILEFPDPRLRTIAKPIETVDDGIRRLIDDMFETMYAAPGIGLAATQVNVHKRLVVMDLSEDKNEPRVFINPEFEALTEELEPYQEGCLSVPGFYENVDRPQKVRIRALDRDGQPFELVAEGLLAVCIQHECDHLNGKLFVDYLSTLKRDRIRKKLEKQHRQHG | Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | C1DFV8 |
A6W5U4 | RS3_KINRD | 30S ribosomal protein S3 | Kineococcus | MGQKVNPFGFRLGITTDHRSRWFADSTKTGQRYADYVKEDVAIRRLMSKGMERAGISKVEIERTRDRVRVDIHTARPGIVIGRRGAEADRIRTELEKLTGKQVQLNILEVKNPEVDAQLVAQGVAEQLASRVSFRRAMRKGMQTTMRSGAKGIRVQCAGRLGGAEMSRSEFYREGRVPLHTLRANIDYGFYEARTTFGRIGVKVWIYHGDITSRELAQSQAAAPRAPRRNERGDRPDRGARRTRPAQDTTAPVAEAVATGSAPTGTAATEPVIGKGSNGTEA | Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation. | A6W5U4 |
Q9ZDT4 | PSD_RICPR | Phosphatidylserine decarboxylase beta chain | typhus group | MKQYNDLFKIIHREGYIFIASFALVSFLLASFNEKLGCIGFIATIWCIYFFRNPDRFVPISDDLVISPADGIIQEIKEASPPPELGLGDLEMIRVSIFLNIFNIHVNRIPANGKILALHYNPGKFFNASLDKASLYNERQSVLMETDQGQKIVFVQIAGLIARRIVCDLEEDNEVKMGERYGIIRFGSRVDVYLPLKTALLVSKGQTAIGGETIIADFGRKKTEEFKFERK | Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). | Q9ZDT4 |
Q9XLE1 | CYB_REDFU | Ubiquinol-cytochrome-c reductase complex cytochrome b subunit | Redunca | MTNIRKTHPLMKIVNNAFIDLPAPSNISSWWNFGSLLGICLMLQILTGLFLAMHYTSDTATAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFMHVGRGLYYGSYMFLETWNIGVILLFATMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIIMALAMVHLLFLHETGSNNPTGISSDVDKIPFHPYYTIKDILGALLLILALMLLVLFTPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILVLMPLLHTSKQRSMMFRPI... | Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is... | Q9XLE1 |
B6HRA4 | SDHF2_PENRW | Succinate dehydrogenase assembly factor 2, mitochondrial | Penicillium chrysogenum species complex | MSAPRILHRVARPVPSSISTITRLNRQFGTTALRLKDGSDEASPEVKAHRANQANKAPNQFVPNTTSTMTKDFVNVGQKPAPPEMLNSANPNYRPSDPYPGRIEHFTGGRQDNGAQKPELGVGEMEGITFKVEPLKRVGEELATKRARLLYQSRKRGILESDLLLSTFADVYLGKMNYDQLVEYDSFLDENDWDIYYWATQDSPEEISPSTPKEDTITETWKESGAKSGEWAQTIGAFRAAYRPVPSRWQNSEVLALLREHVRDKSATGFEKAKNKKTGGGGGLGRMPDVQVFNSGHIVHRRHVLRMLYI | Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduct... | B6HRA4 |
P58793 | PURA_FUSNN | IMP--aspartate ligase | Fusobacterium | MAGYVVVGTQWGDEGKGKIIDVLSEKADYVVRFQGGNNAGHTVVVDGEKFILQLLPSGVLQAGTCVIGPGVVIDPKVFLDEIDRIEKRGAKTDHVIISDRAHVIMPYHIEMDKIRESVEDRIKIGTTKKGIGPCYADKISRDGIRMSDLLDLKQFEEKLRYNLKEKNEIFTKIYGLEPLDFDTIFEEYKGYAEKIKHRIVDTIPMVNKALDENKLVLFEGAQAMMLDINYGTYPYVTSSSPTLGGVTTGAGISPRKIDKGIGVMKAYTTRVGEGPFVTEIKGEFGDKIRGIGGEYGAVTGRPRRCGWLDLVVGRYATEIN... | Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. | P58793 |
B9DNH1 | YQGF_STACT | Putative pre-16S rRNA nuclease | Staphylococcus | MLTHKIIGLDVGSKTVGVAVSDLMGWTAQGLDTLRINEEENELGITKLAEIIKKEDADTVVIGLPKNMNNSIGFRGEASLKYKEELLKILPDINVVMWDERLSTMAAERSLLEADVSRSKRKKVIDKMAAVFILQGYLDSLQ | Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA. | B9DNH1 |
Q2V3I3 | EPFL4_ARATH | CHALLAH-LIKE2 | Arabidopsis | MGTFRRRRRFLLAALVTFALLHLFSASSIVSADGRWIGQRTGSDLPGGFIRSNKRFGGPGSSPPTCRSKCGKCQPCKPVHVPIQPGLSMPLEYYPEAWRCKCGNKLFMP | Acts primarily as positive regulator of inflorescence growth. Endodermal expression is sufficient for proper inflorescence architecture . Redundantly involved with EPFL6 in procambial development regulation. Controls stomatal patterning. Mediates stomatal development inhibition. TMM (AC Q9SSD1) functions to dampen or b... | Q2V3I3 |
A1SA65 | PURA_SHEAM | IMP--aspartate ligase | Shewanella | MGKNVVVLGTQWGDEGKGKIVDLLTEQAKYVVRYQGGHNAGHTLVIDGVKTVLHLIPSGILRDNVKCIIGNGVVLAPDALMKEISMLKERGVPVEDRLLISEACPLILPFHCAVDIAREKARGNKAIGTTGRGIGPAYEDKVSRRGLRVGDLFNAELFAEKLKEVMKYHNFMLTEYYGAEAVDYQTTLDDALAMADYLKSMCVDVTEMLDQARKAGENILFEGAQGTLLDIDHGTYPFVTSSNTTAGGVATGSGFGPCHLDYVLGIMKAYTTRVGAGPFPTELECEIGDHLGTKGHEFGATTGRKRRPGWLDAVAMKRAI... | Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. | A1SA65 |
Q2W548 | COXX2_MAGSA | Heme O synthase 2 | Magnetospirillum | MTANLKVLASVFKLRIGVFCALAAIAGALATPGAVPDFAPVMAVALAVLLSAAAAGAFNHYWERDIDPMMNRTRNRPFATGQFAAGPLWPLGLLALTVAAVALAAFAANAWAALHVFLGAFVYGIVYTVWLKRRTAWNIVIGGLSGSFAVLAGAAVAVPTLSPESLILALVLFLWTPPHFWSLATALKDDYAAAGIPMLPVVCSETETNRIILANTIALVASSLLPAFFGAGPLYLGAAILGGGWFLYKSVALVRRPGRKAAMGNFFASLIQLVLLLTAVMVEPLLAG | Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. | Q2W548 |
Q6CMK7 | SLD1_KLULA | Delta 8-(E)-sphingolipid desaturase | Kluyveromyces | MSRVLSRRDIADRIAKGQTIVIYEDSVLNLDKWIKFHPGGDKSIYHMIGRDATDEMNAYHDDQTITKFKIWKIGRIDYPWENMLPPIQGGRFSKIDERDDIGDYDINLTSKWRSVDESNQYTKIPKNDRLASEAEVKIYPKIPQGVVPSLDLKEAYEKKIVVDPAIVSENYDNERVYEDLTNFPSLDVKNQEWIASEYRKLHGEITAAGLYQCNYVRYLKEFLRIGTLFGISFYLLSLKWFAISAICLGFAWQQLVFIAHDAGHISITHNYQVDNIIGMTVASWIGGLSLGWWKRNHNVHHLVTNDPVHDPDIQHLPFFA... | Delta(8)-fatty-acid desaturase which introduces a double bond at the 8-position in the long-chain base (LCB) of ceramides. Required for the formation of the di-unsaturated sphingoid base (E,E)-sphinga-4,8-dienine during glucosylceramide (GluCer) biosynthesis. | Q6CMK7 |
B3H6D0 | HIP45_ARATH | Heavy metal-associated isoprenylated plant protein 45 | Arabidopsis | MFDWIHGNSRLPIALSIVELLVDMDCKGCEKKVRRAISKLDGVDTVEIDVDRQKVTVTGYVDREEVLKMVKRTGRTAEYWPFPYNGYYGDYYTYPSQHLEQSDQKIYQTISYSGKYDFYDVDDFQNTNNSTINGYYPSSSQKVQPNIDENALHLFSDDNAHACTIM | Heavy-metal-binding protein. | B3H6D0 |
A5D9W7 | MCA1_PICGU | Metacaspase-1 | Meyerozyma | MFPGSGRQTYQQQGYPPPQGAPQYNYGPPQGPPQGYYNGPPQGYNGPPQGPPPQNYNYGHYGPPQGQGQGYGQGGPAPQMYNNNRQSGAMNDVSTAPQRFGNTDMTYQLSNCSGRKKALLVGINYFGSSNELRGCVNDIKNMSNFLNRRFGYSYDDMVILTDDQNQRNKIPTKENIIRAMQWLVKDARPNDSLVFHYSGHGGITKDLDGDEDEGYDEVIYPVDFQQAGHIVDDDMHAIMVRPLPPGCKLTALFDSCHSGTALDLPFVYSTKGVVKEPNLWKDAGTDAFGAFMQYERGNIGGAISSIGGLLKKVTNSSSSN... | Involved in cell death (apoptosis). | A5D9W7 |
Q3Z2G2 | MNTP_SHISS | Probable manganese efflux pump MntP | Shigella | MNITATVLLAFGMSMDAFAASVGKGATLHKPKFSEALRTGLIFGAVETLTPLIGWGMGMLASRFVLEWNHWIAFVLLIFLGGRMIIEGFRGADDEDEEPRRRHGFWLLVTTAIATSLDAMAVGVGLAFLQVNIIATALAIGCATLIMSTLGMMVGRFIGSIIGKKAEILGGLVLIGIGVQILWTHFHG | Probably functions as a manganese efflux pump. | Q3Z2G2 |
Q2LWT5 | DUT_SYNAS | dUTP pyrophosphatase | Syntrophus | MTGIRISVQTLPHFEGLSLPRYMSEHAAGMDICAAVADEVVILPGERALIPTGIAIALPEGFEAQIRPRSGLALKHGVTLVNAPGTIDADYRGEIGVLLINHGNDPFVVARGSRVAQMVIAPVCRVAWSESGSLETTTRGDGGFGHTDES | This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | Q2LWT5 |
O48109 | CYB_PYTRG | Ubiquinol-cytochrome-c reductase complex cytochrome b subunit | Python | MPHHYILTLFGLLPVATNISTWWNFGSMLLTCLMLQVLTGFFLAVHYTANINLAFSSIIHITRDVPYGWLMQNLHAIGASMFFICIYIHIARGLYYGSHLNKETWMSGITLLITLIATAFFGYVLPGGQMSFRAATGITNLLTAVPYLGATMTTWLWGGFAINDPTLTRFFALHFILPFAIISLSSLHIILLHEEGSSNPLGTNPDIDKIPFHPYHSYKDLLLLTLMLLTLMITVSFFPDIFNDPDNFSKANPLVTPQHIKPEWYFLFAYGILRSIPNKLGGALALVMSIMILLTAPLTHTAHLRPMTFRPLSQLMFWTL... | Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is... | O48109 |
Q6X4A2 | CIPKV_ORYSJ | OsCIPK31 | Oryza sativa | MYRAKRAALSPKVKRRVGKYELGRTIGEGTFAKVRFAKNTENDEPVAIKILDKEKVQKHRLVEQIRREICTMKLVKHPNVVRLFEVMGSKARIFIVLEYVTGGELFEIIATNGRLKEEEARKYFQQLINAVDYCHSRGVYHRDLKLENLLLDASGNLKVSDFGLSALTEQVKADGLLHTTCGTPNYVAPEVIEDRGYDGAAADIWSCGVILYVLLAGFLPFEDDNIIALYKKISEAQFTCPSWFSTGAKKLITRILDPNPTTRITISQILEDPWFKKGYKPPVFDEKYETSFDDVDAAFGDSEDRHVKEETEDQPTSMNA... | Involved in cold stress tolerance. CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner. | Q6X4A2 |
Q0SXQ7 | UBIA_SHIF8 | 4-HB polyprenyltransferase | Shigella | MEWSLTQNKLLAFHRLMRTDKPIGALLLLWPTLWALWVATPGVPQLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTANRPLPSGAVTEKEARALFVVLVLISFLLVLTLNTMTILLSIAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAAVSESVPLSCWLMFLANILWAVAYDTQYAMVDRDDDVKIGIKSTAILFGQYDKLIIGILQIGVLALMAIIGELNGLGWGYYWSIVVAGALFVYQQKLIANREREACFKAFMNNNYVGLVLFLGLAMSYWHF | Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-... | Q0SXQ7 |
Q6MC72 | AMPA_PARUW | Leucyl aminopeptidase | Candidatus Protochlamydia | MEFALTLHIEKRKKADVLVLPFWKGTSQPEAAIALHPLKLSLDSVFNTGDFKGKEGETLFLYVEGLVEMRVALLGLGEKNKVSTEALRKSYGCLAKACLGKKLKTLNILMPEFNKTEEDAFIKAITEGLLLPNYVYDRLKSKQEEDDEVTLLQKINFISSNKHVLALAEEVAAICDGVYYTRDLINGNADEITPQYLAKCAQGLSQEYPQIKTTVFDKKRLEKEQMGLLLAVNRGSNLDPTLIIMEYKGNPKSKDHTVIIGKGVTYDTGGLNIKPTGGIETMKCDMSGGAACFGTMLAACHLDLKVNLTAIIPATENSVD... | Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. | Q6MC72 |
B1JT65 | RIMO_BURCC | Ribosome maturation factor RimO | Burkholderia cepacia complex | MSQSPKVGFVSLGCPKALVDSEQIITQLRAEGYEISGSYDGADLVVVNTCGFIDEAVQESLDAIGEALTENGKVIVTGCLGAKSSASGSNLIEEVHPKVLAVTGPHAVGEVMQAVHSHLPKPHDPFVDLVPAAGIKLTPRHYAYLKISEGCNHRCTFCIIPSMRGDLVSRPVAEVMLEAENLFKSGVKELLVISQDTSAYGVDVKYRTGFWNGKPIKTRMTDLVAALGELAAQYGAWVRLHYVYPYPSVDEVIPLMAEGPFKGHVLPYLDVPFQHAHPEVLKRMKRPANAEKVLERVQKWREICPDLTIRSTFIAGFPGE... | Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12. | B1JT65 |
Q8RGE1 | ATPG_FUSNN | F-ATPase gamma subunit | Fusobacterium | MPGMKEIKSRIKSVQSTRQITNAMEIVSTTKFKRYSKLVTESRPYEESMRKILGNIASGVKNEGHPLFDGRKEVKSIAIIVITSDRGLCGSFNSSTLKELEKLVEKNKNKNITIIPFGRKAIDFITKRNYEFSESFSKISPDEMNKIAGEISEEVVEKYNNHIYDEVYVIYNKFISALRYDLTCERIIPITRPEVELNSEYIFEPSTEYILSALLPRFINLQIYQAILNNTASEHSARKNSMSSATDNADEMIKTLNIKYNRNRQSAITQEITEIVGGASAL | Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. | Q8RGE1 |
Q9Y3Y2 | CHTOP_HUMAN | Small arginine- and glycine-rich protein | Homo | MAAQSAPKVVLKSTTKMSLNERFTNMLKNKQPTPVNIRASMQQQQQLASARNRRLAQQMENRPSVQAALKLKQSLKQRLGKSNIQARLGRPIGALARGAIGGRGLPIIQRGLPRGGLRGGRATRTLLRGGMSLRGQNLLRGGRAVAPRMGLRRGGVRGRGGPGRGGLGRGAMGRGGIGGRGRGMIGRGRGGFGGRGRGRGRGRGALARPVLTKEQLDNQLDAYMSKTKGHLDAELDAYMAQTDPETND | Required for effective mRNA nuclear export and is a component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, bind... | Q9Y3Y2 |
Q471H6 | HUTG_CUPPJ | Formiminoglutamate hydrolase | Cupriavidus | MRMAVTQNPWQGRVDSGEVGDTTRLFRIVNTLESSEAKTLGGSPVLLGFGCDAGVLRNQGRAGAAHGPDAIRQALANVPAHGLPALYDAGNIACEHGDLESAQLALAGSVHNILSRGGFPLVLGGGHEVAWGTWQGLRAHLDARNDDGRLLIINIDAHFDLRTSRPASSGTPFDQIANACAERGQPFDYVCLGVSRLSNTPALFSRAHALGVSYVEDVDMQERHLASRLAELAARIDATDHVYLTIDLDALPATVMPGVSAPAAYGVPLPVVEEIALLARRSGKLRAADLAEYNPQYDRDNLGARVAARLAWRLLG | Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide. | Q471H6 |
B8J823 | SYT_ANAD2 | Threonyl-tRNA synthetase | Anaeromyxobacter | MSDLVKVTLPDGSQKEAPRGTPVIDFVKGQIGPGLAKAAYFARLDGEPVDLSRAIERDARLEIVTTRNPEALEVARHDAAHVMASVVQKLYPGTQVTIGPAIEDGFYYDFARETPFTPEDLERIEKATNEAIKADLPFVRSEISMEAALALFEGMGERYKVEIVKDIAAKGAKTLTLYKHGDWVDFCLGPHGPSTGRIGVVKLLNVAGAYWRGDAKNAMLQRIYGTAFFDKKELDAHLAKLEEVKKRDHRRLGPQLGLFTFHEFAPGAPFWLPAGTVLYNVLEDAMRRLVLKNGYQEVKTPLLFNKRLWETSGHWGKYRE... | Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr). | B8J823 |
A6SX19 | EFP_JANMA | Elongation factor P | Janthinobacterium | MKPAKEIRVGNIIMVDSKPMIVLRSDVNGSSRTGFTYKWKMKNLLTNTPMENVFRGDDKFDVVVLDKKPVTYSYFADPLYVFMDEEYNQYEIEEENLGDALHYLKDGMECEAVFYDGKAISVELPITIARQVVYSEPAVKGNTSGNVLKEAKIENAVEAHRHTVQVPLFVSQDDVIEIDTRTNEYKRVVRN | Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | A6SX19 |
A9M0D4 | RUVC_NEIM0 | Holliday junction resolvase RuvC | Neisseria | MAASVRILGIDPGSRVTGFGVIDVRGRDHFYVASGCIKTPADAPLADRIAVIVRHIGEVVAVYKPQQAAVEQVFVNVNPASTLMLGQARGAALAALVSHKLPVSEYTALQVKQAVVGKGKAAKEQVQHMVVQMLGLSGTPQADAADGLAVALTHALRNHGLASRLNPSGMQVKRGRFQ | Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | A9M0D4 |
Q9QZL9 | DKKL1_MOUSE | Protein soggy-1 | Mus | MCRLRVLLLLLPLAFVSSSALPIHDVDSQQNTSGFLGLQRLLQSFSRLFLKNDLLRDLDNFFSSPMDFRDLPRNFHQEENQEHRMGNHTLSSHLQIDKVTDNQTGEVLISEKVEASIEPERNPEGDWKVPKVEAKEPPVPVQKVTDSLHPEPRQVAFWIMKMPRRRTQPDVQDGGRWLIEKRHRMQAIRDGLRGGAREDSLEDGVHIPQHAKLPVRKTHFLYILRPSQQL | Involved in fertilization by facilitating sperm penetration of the zona pellucida . May promote spermatocyte apoptosis, thereby limiting sperm production. In adults, may reduce testosterone synthesis in Leydig cells . Is not essential either for development or fertility . | Q9QZL9 |
Q7WI95 | IXTPA_BORBR | Nucleoside-triphosphate pyrophosphatase | Bordetella | MSAEILNPNLRRVVLASNNAGKLREFSALFAPLGIELVPQSELGVSEAEEPHATFVENALAKARHASRHTGLPALADDSGLCVVALGGAPGVHSARYAQQPGGARSDAANNALLVRELAAAGDRRAWYVALLALVRTENDPCPLIGEGLWHGEIVDAPAGEHGFGYDPHFYLPQQGCTAAQLAPEHKNRISHRAQALAQLLDKLRATGPVDRP | Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical p... | Q7WI95 |
Q1QDK7 | SYP_PSYCK | Prolyl-tRNA synthetase | Psychrobacter | MKASQFLFATLKETPSDADIASSQLMVRAGLIRKIASGLYIWLPMGLRVLQKVERIVREEMQNIGAQEVLMPMTQPAELWQLTGRFNDYGPELLRFKDRHDRDFVLGPTHEEVITNLAQGELRSYKQLPITFFQIQNKFRDEIRPRFGVMRAREFTMKDAYSFHVDQASLAKTYDEMYDAYTRIFTRLGLDFRAVQADTGSIGGFASHEFHVLADSGEDDIAFSDSSEYAANVELAESVSMAERQPATMARENIDTVNMPTCEAVAEHLNVPLATTVKTLIVQGHTPEGEPQLIAVVLRGDHTLNTIKAEKIEEANVPLM... | Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two addit... | Q1QDK7 |
P62590 | INT2_ECOLX | E2 protein | Escherichia | MKTATAPLPPLRSVKVLDQLRERIRYLHYSLRTEQAYVHWVRAFIRFHGVRHPATLGSSEVEAFLSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPWLQEIGRPRPSRRLPVVLTPDEVVRILGFLEGEHRLFAQLLYGTGMRISEGLQLRVKDLDFDHGTIIVREGKGSKDRALMLPESLAPSLREQLSRARAWWLKDQAEGRSGVALPDALERKYPRAGHSWPWFWVFAQHTHSTDPRSGVVRRHHMYDQTFQRAFKRAVEQAGITKPATPHTLRHSFATALLRSGYDIRTVQDLLGHSDVSTTMIYTHVLKVGG... | Putative integrase believed to be involved in the insertion of antibiotic resistance genes into plasmids and transposons. | P62590 |
E3PQQ8 | CCAP_CONVL | ConoCAP-c | Dauciconus | MVSLGHVLFVILLPVLLPVAADDPDDQMLSQISLPSSSRSEYDDNDVSKRVFCNGFTGCGGRHRDRSRRQERYGKRLIPVLAKRPFCNSFGCYNGKRSLSGAGPALSTPVDPSRNNKARTMARMLDAAASARHEQQQQLLQQREQRGLESRDPAASGDLSKRLFCNGYGGCRGGKRTLYSPWLERMNEVADDRSARNALCTRLGWRE | Synthetic conoCAP-c decreases the heart frequency of 12% in Drosophila larvae. | E3PQQ8 |
Q8LPS1 | LACS6_ARATH | Long chain acyl-CoA synthetase 6, peroxisomal | Arabidopsis | MDSSSSSSSAAARRRINAIHSHLVTSSRSSPLLRSNPTAGEFCLDNGYSVVLPEKLNTGSWNVYRSAKSPFKLVSRFPDHPDIATLHDNFEHAVHDFRDYKYLGTRVRVDGTVGDYKWMTYGEAGTARTALGSGLVHHGIPMGSSVGIYFINRPEWLIVDHACSSYSYVSVPLYDTLGPDAVKFIVNHATVQAIFCVAETLNSLLSCLSEMPSVRLVVVVGGLIESLPSLPSSSGVKVVSYSVLLNQGRSNPQRFFPPKPDDVATICYTSGTTGTPKGVVLTHANLIANVAGSSFSVKFFSSDVYISYLPLAHIYERANQ... | Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation (Probable). Preferentially uses palmitate, palmitoleate, oleate, linoleate and eicosenoate as substrates . Can use myristate and linolenate as substrates . May play a regulatory role both in fatty acid import ... | Q8LPS1 |
Q6MPX9 | MACB_BDEBA | Macrolide export ATP-binding/permease protein MacB | Bdellovibrio | MIDIKGIRKSYQMGDTKVDVLKGISLKIERGDFVAIMGPSGSGKSTLMHILGLLDVPSEGSYNLNGREVADLSEDELAIVRREEIGFIFQQFNLLPRMEAWQNVSLPLIYSEDGFSYDKAQALLDKVGLAERIHHKSNELSGGQQQRIAIARSLINNPRIIFADEPTGNLDSKSEKEIIQILHKLNDQGITVIVVTHEEEIGQQAKRLIRLRDGVIQSDERLQALPAAPTTAQEKRQEKTAKWPVREMIEHLHQGFQTLAANKVRSGLSMLGILIGVAAVVGMLALGTGARQSIEKQLSSLGSNLLVLRAGNVRVGGVMQ... | Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Q6MPX9 |
Q8WUH2 | TGFA1_HUMAN | Transforming growth factor-beta receptor-associated protein 1 | Homo | MMSIKAFTLVSAVERELLMGDKERVNIECVECCGRDLYVGTNDCFVYHFLLEERPVPAGPATFTATKQLQRHLGFKKPVNELRAASALNRLLVLCDNSISLVNMLNLEPVPSGARIKGAATFALNENPVSGDPFCVEVCIISVKRRTIQMFLVYEDRVQIVKEVSTAEQPLAVAVDGHFLCLALTTQYIIHNYSTGVSQDLFPYCSEERPPIVKRIGRQEFLLAGPGGLGMFATVAGISQRAPVHWSENVIGAAVSFPYVIALDDEFITVHSMLDQQQKQTLPFKEGHILQDFEGRVIVATSKGVYILVPLPLEKQIQDL... | Plays a role in vesicle-mediated protein trafficking of the endocytic membrane transport pathway. Believed to act as a component of the putative CORVET endosomal tethering complexes which is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE co... | Q8WUH2 |
A8ESU8 | RL22_ALIB4 | 50S ribosomal protein L22 | Aliarcobacter | MAKAILKFIRVSPIKARLIAREVQGMNAEYAIASLQFTPNKAAGIISKVIASAVANAGLDPVDAVITSARVDKGPVLKRFTPRARGSASPKHKPTAHIMIEVAAATKGDK | The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. | A8ESU8 |
Q2S919 | RL16_HAHCH | 50S ribosomal protein L16 | Hahella | MLQPKRTKFRKVHKGRNTGLAQRGNKVSFGEFGLKATGRGRITARQIEAARRTMTRRIKRGGKIWIRIFPDKPITKKPLEVRMGKGKGPVEYWVAEIEPGRMLYEMEGVSEELAREAFTLAAAKLPVATTFVTRTVM | Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs. | Q2S919 |
Q4AAV4 | OBG_MESHJ | GTP-binding protein Obg | Mesomycoplasma | MRFVDYVSIEVVAGKGGDGIISFRREAHVDKGGPDGGDGGWGGSIYFVGDSGMNTLLPFYQTKKIFGYNGENGRPKRQTGANGKDIFIKVPLGTQVFLKKSLICDIILEKKYLIAKGGRGGLGNFHFRNSKNKAPRISENGELGQNFYLDLQLKVMADIGLVGKPNAGKSTLLSLISNSKPKIANYEFTTLAPQLGVVKIYENSFVTADLPGLIQGASSGKGMGIIFLKHIERCRAIVHVIDFGSDNKNPIKDFIEIKSELEKFNKKLLDLNQIVIANKCDLPNFQFNLANFKRKFPKIKIIKSSLISAKQNEINIIKEK... | An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. | Q4AAV4 |
P49765 | VEGFB_HUMAN | VEGF-related factor | Homo | MSPLLRRLLLAALLQLAPAQAPVSQPDAPGHQRKVVSWIDVYTRATCQPREVVVPLTVELMGTVAKQLVPSCVTVQRCGGCCPDDGLECVPTGQHQVRMQILMIRYPSSQLGEMSLEEHSQCECRPKKKDSAVKPDRAATPHHRPQPRSVPGWDSAPGAPSPADITHPTPAPGPSAHAAPSTTSALTPGPAAAAADAAASSVAKGGA | Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis. | P49765 |
A7FLI9 | DPO4_YERP3 | DNA polymerase IV | Yersinia | MRKIIHVDMDCFFAAVEMRDDPRLRDIPLAIGGSKERRGVISTANYPARRYGVRSAMPTAMAFKLCPQLTLLPGRMAAYKEASQHIREIFARYTPLIEPLSLDEAYLDVSDSLACGGSATLIAQEIRQSIASELNLTASAGIAPIKFLAKIASELNKPNGQYVITPNQIQPFLQDLPLSKIPGVGAVTAKRLQALGLVTCGEIQKYPLAELLKHFGKFGRVLWERSHGIDEREISPDRLRKSVGVEKTLAEDIYDWESCEALIEELYLELETRLRKVKPDLHIARQGVKLKFHDFQQTTQEHTWPVLNKADLLQIAHAAW... | Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in... | A7FLI9 |
Q9AP06 | KATG_BURCE | Peroxidase/catalase | Burkholderia cepacia complex | MSNEGQCPFNHANGGGTTNRDWWPNELRLDLLSQHSSKTDPLDPGFNYAEAFNSLDLDALRKDLAALMTDSQDWWPADFGHYGPLFVRMAWHSAGTYRMGDGRGGAGRGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGQKISWADLLILTGDVALTTMGFKTFGYAGGREDTWEPDRDVYWGSETTWLGGDLRYDKGGACESQHGGNAGRNLENPLAAVQMDLIYNPEGGPDGNPDPVAAAYDIREVFGRMAMNDEETVALIAGGHAFGKTHGAGPADNVGLEPEAAGLEQQGLGWKNSFGTGKGADTITSGLEVTWS... | Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity. Required for maintaining the normal activity of the TCA cycle. | Q9AP06 |
Q07V79 | RBFA_RHOP5 | Ribosome-binding factor A | Rhodopseudomonas | MPRHHQKNSGREASQRQLRVGESVRHAIAEILAQGGVHDPVLEGHLVTVPEVRMSPDLKLATIYVMPLGGRDTELVLKALDHNKKFLRGEVSRRVNLKFAPELRFRADDRFDEAERIEKLLRTPAVQRDLQHDSDESE | One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal heli... | Q07V79 |
Q03614 | NTDO_CAEEL | Sodium-dependent dopamine transporter | Caenorhabditis | MQLVPTDDPDEKIGRTSNGMQNATLPIDGPVNTEPKDPAREQWSGKLDFLLSVVGFAVDLGNIWRFPYLCFKNGGGVFLIPYSIMVLLTGVPLFYMELCLGQYYRKGAITTWGRICPLFKGIGYCVILTAFYVDFFYNVILAWGLHYLYTSFSFNLPWASCNNSYNSPACYEPHWSEDGTAMCRSANQSVSAEKISAAEEYFYKGFLGLHEANAPNSHVIRSVTDLGNVRWDIALSLFVVYLICYFSMWKGIHTSGKVVWFTALFPYVVLGILFIRGVTLPGWQNGIEYYLRPNFEMLKRPSVWQDAATQVFFSLGPGFG... | Dopamine transporter . Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals. | Q03614 |
Q9WUH7 | SEM4G_MOUSE | Semaphorin-4G | Mus | MWGRLWPLLFSFLTVTAVPGPSLRRPSRELDATPRLTISYEELSQIRHFKGQTQNYSTLLLEEASERLLVGARGALFSLSARDIRDRTHKEIHWEASPEMQSKCHQKGKNNQTECFNHVRFLQRLNATHFYACGTHAFQPLCAAIDAETFILPTSFEEGKEKCPYDPARGFTGLIIDGGLYTATRYEFRSIPDIRRSRHPHSLRTEEAPMHWLNDAEFVFSVLVRESKTSAVGDDDKIYFFFMEREEGSSSFTQSRSSHRVARVARVCKGDLGGKKILQKKWTSFLKARLICHIPQYETLRGVCSLNADTSSHTHFYAVF... | Cell surface receptor for PLXNB2. May play a role in axon guidance. | Q9WUH7 |
P69929 | TX9A_ANTMC | Peptide toxins Am-1 | Antheopsis | MKRIFIVALLFATCLVNAKPSINDADIKREPEPNVAVPPCGDCYQQVGNTCVRVPSLCPSRKREPEPNVAVPPCGDCYQQVGNTCVRVPSLCPSRKREPEPNVAVPPCGDCYQQVGNTCVRVPSLCPSRKREPEPNVAVPPCGDCYQQVGNTCVRVPSLCPSRKREPEPNVAVPPCGDCYQQVGNTCVRVPSLCPSRKREPEPNVAVPPCGDCYQQVGNTCVRVPSLCPSRKR | May inhibit voltage-gated sodium channels (Nav). | P69929 |
B0C0B6 | RECO_ACAM1 | Recombination protein O | Acaryochloris | MSRTYKATGINLKSMPFGEADRLLTILTREQGLVRAVAPGCRKPKSKLGGRSALFVVNDLMLVQGRSLDKIAQAETLESYPGLSQNLAKLTTSQYLAELTLYQALSGQPQTELWDLFCQQLTQLQNATLAQVPCCLIHGTLKLLAGAGIAPQVHACCVTHQPLDPPTSNPTWRVGFSAGAGGTVTLTGPPRPRTAIQQAAEQAIAYPLGADYRVQGKLSAQELALLQDLNPAEIQPASPLPLPLIATYPLVIWQGVESALRHYAEAYFDRPIRSAALIDTCFTPLPDLTSVPS | Involved in DNA repair and RecF pathway recombination. | B0C0B6 |
B1YLP7 | EFP_EXIS2 | Elongation factor P | Exiguobacterium | MVSVNDLKTGLTIKTSDGMIWQVLEFQHVKPGKGAAFVRTKMRNIRNGNIQEMTFRGGERVERAHIERNKMQYLYPMGETYVFMDTESYEQLELTTAQVEAALPFLLENMEVQIAIYNGEVLGIELPNTIVMTIVEAEPGVKGDTASNVKKNATVETGHIIHVPLFIEAGEKVTVDTRTGDFTGRYNG | Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | B1YLP7 |
Q73X85 | MURI_MYCPA | Glutamate racemase | Mycobacterium avium complex (MAC) | MSSALAPVGIFDSGVGGLTVARAIIDQLPDEHIIYVGDTGHGPYGPLSIPEVRAHALAIGDDLVGRGVKALVIACNTASAACLRDARERYEVPVVEVILPAVRRAVATTRNGRIGVIGTQATINSHAYQDAFAAARDTEITAVACPRFVDFVERGVTSGRQVLGLAEGYLEPLQRAQVDTLVLGCTHYPLLSGLIQLAMGDNVTLVSSAEETAKEVLRVLAERDLLHPHPDDPRAAGPSRVFEATGDPEAFTRLAARFLGPAVSGVRPVHHVRID | Provides the (R)-glutamate required for cell wall biosynthesis. | Q73X85 |
Q0HKG4 | G1091_SHESM | Glycosyl hydrolase family 109 protein 1 | Shewanella | MHNIHRRHFLKAAGAVTAGLVTANIALNANASSVAPKPRVGKSVIGLIAPKMELVRVGFIGVGERGFSHVEQFCHLEGVELKAICDTHQAVIDRAVEHIVNQNRPKPAVYTGNDLSYRELLNRDDIDIVIISTPWEWHAPMAIDTMESGKHAFVEVPLALTVEECWQLVDTAERTQKNCMMMENVNYGREELMVLNMVRQGVFGELLHGEAAYIHELRWQMKEIDHKTGSWRTYWHTKRNGNLYPTHGLGPISQYMNINRGDRFDYLTSMSSPALGRTLYAKREFPADHERNQLKYINGDMSTSLIKTVKGRTIMVQHDT... | Glycosidase. | Q0HKG4 |
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