accession stringlengths 6 10 | name stringlengths 6 11 | Full Name stringlengths 1 147 ⌀ | taxon stringlengths 3 46 ⌀ | sequence stringlengths 16 2.75k | function stringlengths 6 5.51k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
Q08219 | RRT8_YEAST | Regulator of rDNA transcription protein 8 | Saccharomyces | MKAGIELISHSQASHATYANSMTLAEKGPQRLKRQFKEHSSSKESNVSRWLKIFIRQFDIWFPETIPTMKVRYELLRKNFIKEIFNSRAFIYPFLGFYEVLTNPVYWKHILLFAVCYALIFVTIAGLFYVTLVPLLVTWAILLLGPLGVILVHIQWILQTNVLTAFVCRTLVLTHITNQIFDISLVLQDQDEFLNEVKVLPKPQKPHRKIDEPDAVRNFNTIKGSRIFKIPRLLFRMFFKVSNFTSLTLLSLIPIVGPILANQLMAPKRTFTYLQRYFLLKGFSKKQAKDFQYEHYASFICFGMSAGLLELIPFFTIVTI... | Involved in spore wall assembly . May be involved in the modulation of rDNA transcription . | Q08219 |
Q5L5D3 | ISPH_CHLAB | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase | Chlamydia | MRRVILSNPRGFCAGVVRAIQVVESALEKWGAPIYVKHEIVHNRHVVDDLKRRGAIFIEDLKDVPCGEKVIYSAHGIPPEVREEAKARNLFDIDATCVLVTKIHSAVKLYASKGYQIILIGKKKHVEVIGIRGEAPESVTVVEKVEDVANLPFDIHVPLFFVTQTTLSLDDVAEVTQALKARYPHIITLPSSSVCYATQNRQEALRAVLPRVNFVYVIGDVQSSNSNRLREVAEKRNIPARLVNSPDHISDEILHYSGDIAVTAGASTPEHIIQSCISRLKELIPDLQVEEDIFTTEDVVFQPPKELRT | Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. | Q5L5D3 |
Q31NM6 | SYDND_SYNE7 | Non-discriminating aspartyl-tRNA synthetase | Synechococcus | MRTHYCGELRAEQVGTSVTLYGWVDRRRDHGGVIFVDLRDRTGTVQIVSDPERTPESYHQAEGLRNEYVVKITGRVSGRPAESLNPKLPTGEVEIYADRIEILNAVRRQLPFQVSSADEETVREDLRLRYRYLDLRRDRMNRNLQLRHQVVKAIRRFLEDEEQFIEIETPVLTKSTPEGARDYLVPSRVNPGEWFALPQSPQLFKQLLMVSGFDRYYQIARCFRDEDLRADRQPEFTQLDMEMSFLSQEEIIDLNERLIAHIFKTVKGIELPRPFPRLTYAEAMDRYGSDRPDTRFGLELVDVSDVVADMGFKVFSGAVK... | Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn). | Q31NM6 |
A3N1D8 | ORN_ACTP2 | Oligoribonuclease | Actinobacillus | MSKLDNQNLIWIDLEMTGLDPEKERIIEVATIVTDKDLNILAEGPVLTVHQSNDLLNKMSDWCIKTHTENGLIERVKQSKLTERAVELQTIDFLKQWVPKGASPICGNSVAQDKRFLYKYMPDLADYFHYRHLDVSTLKELARRWKPDMLNAFNKKNTHLALDDIRESIEELKFYRTHFINLEK | 3'-to-5' exoribonuclease specific for small oligoribonucleotides. | A3N1D8 |
Q5SD05 | ATPE_HUPLU | F-ATPase epsilon subunit | Huperzia | MTLNLRVMTPNRTVWNSEVQEMILSTNSGQIGVLPNHAPLLTALDIGITKIRLNGQWSTMALMGGFAMVDNNQVTILVNEAEEAAGIDPQEAKETFRIAQTNLARAEGKKQVIEANLAFKRAKARLEAIDATLSYASN | Produces ATP from ADP in the presence of a proton gradient across the membrane. | Q5SD05 |
P00919 | CAH2_RABIT | Carbonic anhydrase II | Oryctolagus | MSHHWGYGKHNGPEHWHKDFPIANGERQSPIDIDTNAAKHDPSLKPLRVCYEHPISRRIINNGHSFNVEFDDSHDKTVLKEGPLEGTYRLIQFHFHWGSSDGQGSEHTVNKKKYAAELHLVHWNTKYGDFGKAVKHPDGLAVLGIFLKIGSATPGLQKVVDTLSSIKTKGKSVDFTDFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPITVSSEQMLKFRNLNFNKEAEPEEPMVDNWRPTQPLKGRQVKASFV | Catalyzes the reversible hydration of carbon dioxide. Involved in the regulation of fluid secretion into the anterior chamber of the eye. Essential for bone resorption and osteoclast differentiation. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorp... | P00919 |
A0LU48 | DOP_ACIC1 | Depupylase | Acidothermus | MHRVMGIETEYGISVPHQPNANAMAASSQVVNAYAPIGAPAQRQARWDFEEENPLRDARGFEVAREAADPSQLTDEDLGLANVILTNGARLYVDHAHPEYSTPEVTNPRDAVLWDKAGERIMAEAARRAADLPMGWTIQLYKNNTDNKGASYGCHENYLMNRSTPFADIVRHLIPFFVTRQVFCGAGRVGIGADGRGEGFQLSQRADFFEVEVGLETTLKRPIINTRDEPHADPEKYRRLHVIIGDANMSEIATYLKLGTTALVLAMIEDGFLSQDFSVESPVGALRAVSHDPTLRYQLRLHDGRRLTAVQLQMEYLEQA... | Displays depupylase (DPUP) activity, removing conjugated Pup from target proteins; is thus involved in the recycling of Pup and may function similarly to deubiquitinases (DUBs) in eukaryotes to prevent or promote proteasomal degradation of certain proteins. Is also able to catalyze the deamidation of the C-terminal glu... | A0LU48 |
A0A2I6PIZ6 | NODD2_HYPPI | Nodulisporic acid biosynthesis cluster protein D2 | Hypoxylon | MDSTGRQPLSQDGQPWQALASGLGFPDEDQKYWWSVMAPLLGELMKWANYPVDKQYLVLAFCHEYILPFCGPRPTAEGGIFWPTLITKDGTPFEPSLNFYKNKATLRVGYAPACELSGSNDDPINQRAPIAALEHQKRVLPQQNLKWVDNFKKAWFIDNDDAVALKARVHNELFEQAAVQCLIGYVFSDYTQVKVAMSPLWKSVQTGQQISRVIWDTFRQLGDDASSYLDCLSVLEEYTESKQAKLAQVQPSFVNFDVNLKGDYQQSRLKVYYATPCTAFDTMVQVFTLGGRLKGPEVDHAIECLRVLWPSVLAVPENHP... | Indole diterpene prenyltransferase; part of the gene cluster that mediates the biosynthesis of the indole diterpenes nodulisporic acids (NA). Nodulisporic acid A (NAA) and its chemically modified derivatives are of particular significance because of their highly potent insecticidal activity against blood-feeding arthro... | A0A2I6PIZ6 |
Q9MZ13 | VDAC3_BOVIN | Outer mitochondrial membrane protein porin 3 | Bos | MCNTPTYCDLGKAAKDVFNKGYGFGMVKIDLRTKSCSGVEFSTSGHAYTDTGKASGNLETKYKICNYGLTFTQKWNTDNTLGTEISWENKLAEGLKLTLDTIFVPNTGKKSGKLKASYKRDCFSLGSNVDIDFSGPTIYGWAVLAFEGWLAGYQMSFDTAKSKLSQNNFALGYKAADFQLHTHVNDGTEFGGSIYQKVNEKIETSINLAWTAGSNNTRFGIAAKYKLDCRTSLSAKVNNASLIGLGYTQTLRPGVKLTLSALIDGKNFNAGGHKVGLGFELEA | Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. | Q9MZ13 |
Q12343 | MED4_YEAST | Mediator complex subunit 4 | Saccharomyces | MSVQDTKAVEFSMGHIRSSSVSLVAEATSNTNSEDKLSKVQLYEDLCRYEDTLSKLVESVDRFKPNLDIAKDLIRTDEALFENVKLLAEYDNIYRNLQKIDKDSEELDSKTRKILEILNECHDELKALPMLEQVEFEKNTILQQRSKINSTELLDYATKLSKFTKIPPTFDKGAVGPNNFIWPAEDALRRGMLAMASLHSKELTRIPGEEVEETEVPTVPPSQSEEQKGQMAKKEGTPKTDSFIFDGTAKEVGDEADNTKDKEKEENNDDALDLDLDLFDPDDF | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a com... | Q12343 |
A5F3F8 | RLMN_VIBC3 | tRNA m2A37 methyltransferase | Vibrio | MTTEKVNLLDFDRKGLRTFFAEELGEKAFRAEQVMKWIYHFGCDDFDQMNNINKQLREKLKAKCEIRAPYVSEAQHSADGTIKWAMRVGDQDVETVYIPEDDRATLCVSSQVGCALECKFCSTAQQGFNRNLRVSEIIGQVWRAAREIGLEKETGRRPITNVVMMGMGEPLLNMKNLIPALEIMLDDLGFGLSKRRVTVSTSGVVSGLEQMIGQIDVALAISLHAPNDKLRSEIMPINDRWNIEAFLEVVRRYIASSNANRGKVTVEYVLLDHVNDGTEHAHELAELLKRTPCKINLIPFNPYPGSPYKKPSNSRIDRFQ... | Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity. | A5F3F8 |
O76093 | FGF18_HUMAN | zFGF5 | Homo | MYSAPSACTCLCLHFLLLCFQVQVLVAEENVDFRIHVENQTRARDDVSRKQLRLYQLYSRTSGKHIQVLGRRISARGEDGDKYAQLLVETDTFGSQVRIKGKETEFYLCMNRKGKLVGKPDGTSKECVFIEKVLENNYTALMSAKYSGWYVGFTKKGRPRKGPKTRENQQDVHFMKRYPKGQPELQKPFKYTTVTKRSRRIRPTHPA | Plays an important role in the regulation of cell proliferation, cell differentiation and cell migration. Required for normal ossification and bone development. Stimulates hepatic and intestinal proliferation. | O76093 |
Q3SVD4 | MUTS_NITWN | DNA mismatch repair protein MutS | Nitrobacter | MMEQYLEIKAANPGLLLFYRMGDFYELFFEDAEIASRALGITLTKRGKHQGADIPMCGVPVERSDDYLHRLIAAGHRVAVCEQTEDPSAARKRGNKSVVRRDVVRLVTPGTLTEDTLLDARANNYLLALARARASSGVDRFALAWIDISTAEFMVTECGANELAATLARINPNEVIVSDTLHGDPDLGALLRELPSVTPLPRDTFDGATAERRLCDYFAVATMDGLSAMSRLEATAAAAAVTYIDRTQIGQRPPLSPPSREASGSTMAIDPATRANLELTRTLAGERRGSLLDAIDRTMTAAGSRLLAQRLAAPLTDTAA... | This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | Q3SVD4 |
C1D9H2 | CCME_LARHH | Heme chaperone CcmE | Laribacter | MHPKRKKRLLIVLAGLAVVAVASGLILNAFRSNLVFFHTPTEIAAGQVDTDRVIRVGGLVEAGSVEREPGGLRVRFVITDTARSVPVRYEGILPDLFREGHGTVVQGRIGTDGVLAATQVLAKHDENYMPPEAADAIQRAGETVVQ | Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. | C1D9H2 |
O32377 | RECA_ALLVI | Recombinase A | Allochromatium | MDENRKKALAAALTQIEKQFGKGSVMRMGDVGAVRNIEAISTGSLGLDLALGIGGVPKGRVIEIYGPESSGKTTLTLHIIAESQKLGGTAAFVDAEHALDPVYAEKLGVNMTDLLVSQPDTGEQALEITDMLVRSGAVDVVVVDSVAALTPKAEIEGEMGDSHVGLQARLMSQALRKLTGNIKRSNCCVIFINQIRMKIGVMFGSPETTTGGNALKFYASVRLDIRRTGAIKKGDEVIGNETKVKVVKNKVAPPFRQAEFDILYGQGISREGEIIDLGVAEGFIDKSGAWYSYDGNRIGQGKDNVRNFLCENPGIAQAIE... | Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage. | O32377 |
A4W787 | RISB_ENT38 | 6,7-dimethyl-8-ribityllumazine synthase | Enterobacter | MNIIEAAVATPDARVAITIARFNNFINDSLLDGAIDALKRIGQVKDENITVVWVPGAYELPLAAGALAKTGKYDAVIALGTVIRGGTAHFEYVAGGASNGLAHVAQEAEIPVAFGVLTTESIEQAIERAGTKAGNKGAEAALTALEMINVLKAIKA | Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | A4W787 |
A9LYF6 | NDHH_ACOAM | NADH-plastoquinone oxidoreductase subunit H | Acorus | MTVPATRQDLMIVNMGPHHPSMHGVLRLIVTLDGEDVIDCEPILGYLHRGMEKIAENRTIIQYLPYVTRWDYLATMFTEAITVNGPEQLGNIQIPKRASYIRVIMLELSRIASHLLWLGPFMADIGAQTPFFYIFRERELIYDLFEAATGMRMMHNYFRIGGVAADLPYGWIDKCLDFCDYFLTGIVEYEKLITQNPIFLERVERVGIISGEEAINWGLSGPMLRASGIEWDLRKVDNYECYNEFDWEVQWQKEGDSLARYLVRISEMKESIKIIQQALEGIPGGPYENLEVRRFDKVKDSEWNDFEYRFISKKPSPTFE... | NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translo... | A9LYF6 |
A5GQJ6 | YCF3_SYNR3 | Photosystem I assembly protein Ycf3 | unclassified Synechococcus | MPRSQRNDNFIDKSFTVMADLILKVLPTNQKAKEAFAYYRDGMSAQGDGEYAEALENYQEALRLEEDPNDRAFILYNMALVYASNGEHNRALEQYEQALALNAKMPQVLNNMAVIHHHLGSIAQEKGESDEADRRFDLAADFWSKAIRLAPNNYIEAQNWLKTTGRGSADVYL | Essential for the assembly of the photosystem I (PSI) complex. May act as a chaperone-like factor to guide the assembly of the PSI subunits. | A5GQJ6 |
A2YWA6 | ZHD2_ORYSI | Zinc-finger homeodomain protein 2 | Oryza sativa | MDFDDHDEGDGDEEMPPMPLSSGYDAPMQPGLGGGGGGVPKPGGGVGGGGGGGGGGGGGGARYRECLKNHAVGIGGHAVDGCGEFMASGEEGSIDALRCAACGCHRNFHRKESESPTGVGPAEPSAVSPAAISAYGASPHHQFSPYYRTPAGYLHHQQHQMAAAAAAAAAAAAGGYPQRPLALPSTSHSGRDEGDDMSGMVGPMVIGPMVGMSLGSAGPSGSGSGKKRFRTKFTQEQKDKMLAFAERLGWRIQKHDEAAVQQFCEEVCVKRHVLKVWMHNNKHTLGKKAP | Putative transcription factor. | A2YWA6 |
B0T192 | GATC_CAUSK | Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C | unclassified Caulobacter | MAIDAATVRKVARLARIATPEDRLEPLAQELNGIMTWIEQLAQVDTDGVEPLTSVVHAGLPLREDVVTMGGDADLITANAPKSTGGFFVVPKVVE | Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated ... | B0T192 |
Q9AKH1 | FER2_RICRI | Adrenodoxin-like protein | spotted fever group | MSGKIKVTFIINDGEEKTVEAPIGLSILEIAHSNDLDLEGACEGSLACATCHVILEEEFYNKLKKPTEAEEDMLDLAFGLTDTSRLGCQIILTEELDGIKVHLPAATRNIKL | Ferredoxin are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. | Q9AKH1 |
Q87LL6 | ARGP_VIBPA | HTH-type transcriptional regulator ArgP | Vibrio | MRGLDYKWIEALDAVVYQGSFERAAEHLFVSQSAISQRIKQLEKFLAQPVLIREQPPKPTPIGKKLLGLYRRVRLLEHEILPEIKNDTTTRPVQLSLATNADSLATWLLPALQDVMKTRQVELKLTIYGESRSIEKLKSGEVAGAISLESQAIPNCRADYLGRIDYVCVANPEFYQRYFSEGVNNQTLAKAPAVSYDQYDDLHKKFLTEHFNVRPDSVIHHNISSSEAFLKMALAGVAYCLIPRLQITDELEQGSLIDITPGFLMSYRIYWHHWQLETGVLQEISQAIVNYAQRHLPQ | Controls the transcription of genes involved in arginine and lysine metabolism. | Q87LL6 |
Q8DW14 | PURA_STRMU | IMP--aspartate ligase | Streptococcus | MTSVVVVGTQWGDEGKGKITDFLSADAEVIARYQGGDNAGHTIVIDGKKFKLHLIPSGIFFPEKVSVIGNGMVVNPKSLVEELDYLHQEGVATDNLRISDRAHIILPYHIKLDQLQEASKGDNKIGTTNKGIGPAYMDKAARVGIRIADLLDKDIFAERLKANLAEKNRLFEKMYESSPVAFDTIFDEYYAYGQKIKDYVTDTSVILNKALDKGRRVLFEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGPFPTELFDQTGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRV... | Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. | Q8DW14 |
A4YKF1 | PROA_BRASO | Glutamyl-gamma-semialdehyde dehydrogenase | unclassified Bradyrhizobium | MTAPLKAIDGSADLPQLMNDLAKRARAAARVLALAPAEQKNRALEAMERRIRARADVIIAANAEDVAEAKAVGVTPSFVDRLTLTPARVAAMADGIAVVRGVADPVGVVTESWQRPNGMTIERVRVPLGVIGVIFESRPNVAADAGVLCLKSGNAVILRGGSDSFRSCRAIHECLVEGLREAGLPDTAITLVPTRDRAAVGLLLSGLNGGVDVIVPRGGKSLVARVEAEARVPVFAHLEGVNHVYVDGAADLDMAKSIVLNAKMRRTGVCGAAETLLIDRASQDKIKPLVDMLIGAGCEVRGDEAVRAADARVTPANNED... | Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. | A4YKF1 |
Q8DM00 | PRMA_THEVB | Ribosomal protein L11 methyltransferase | Thermosynechococcus | MVQRWWEITVTCQAEAEELVYWRLQSFGCQGTATQLQQGRVLIQGYVPQQRVSLLDIAALGVWIEQDVVAQGYLSPKLHWQLVNEQDWAHSWQAYWHPIPVGDRLLICPAWEMPPLDNTRLVIKLDPGMAFGTGTHETTQLCLEALEMQLDQTFEPLPPTVIADIGCGSGILAIASLLLGAQKAYAVDTSDLAVTATQRNAELNGIRADQLIVHQGSWEQVLELVDGVVCNILAPVIIEILPHLPAIVKPKGWGIFSGILLDQADRVAEQLKRQGWSLGSVWRRNEWCCLNARFERLPD | Methylates ribosomal protein L11. | Q8DM00 |
O46629 | ECHB_BOVIN | Beta-ketothiolase | Bos | MISLLTYTLKNLPNTSKWALRFCMRPLSSSSQLQAAAASQTKSKKTLAKPNIRNIVVVDGVRTPFLLSGTSYKDLMPHDLARAALSGLLHRTSVPKDVVDYIIFGTVIQEVKTSNVAREAALGAGFSDKTPAHTVTMACISSNQAMTTAVGLIASGQCDVVVAGGVELMSDIPIRHSRKMRKMMLDLNKAKTLAQRLSIISKFRLNFLSPELPAVSEFSTSETMGHSADRLAAAFAISREEQDEYALRSHSLAKKAQDEGLLSDVVPFKVPGRDTVTQDNGIRPSSLDQMAKLKPAFIKPYGTVTAANSSFLTDGASAVL... | Mitochondrial trifunctional enzyme catalyzes the last three of the four reactions of the mitochondrial beta-oxidation pathway. The mitochondrial beta-oxidation pathway is the major energy-producing process in tissues and is performed through four consecutive reactions breaking down fatty acids into acetyl-CoA. Among th... | O46629 |
A7GJW3 | PTH_BACCN | Peptidyl-tRNA hydrolase | Bacillus cereus group | MKLIVGLGNPGREYELTRHNIGFMAIDELAKRWNISLNEQKFKGMFGAGFVNGEKVILLKPLTYMNLSGESIRPLMDYYKIDLEDFIIMYDDLDLPVGKLRLRMKGSAGGHNGVKSTIAHLGTQEFQRIRMGIDRPKNGMKVVDYVLGRFTAEEMVDVNHAIEKAANACEEWLNKSFLQVMNDFNN | The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. | A7GJW3 |
C3P786 | DEOC_BACAA | Phosphodeoxyriboaldolase | Bacillus cereus group | MNIAKLIDHTILKANTTKEDVMKVIEEAKEYKFASVCINPTWVKLAAEELAGHDVDVCTVIGFPLGASTTETKAFETKDAIAKGATEVDMVINVGALKDGDNELVEKDIYEVVQAAKGKALVKVIIETCLLTDEEKVRACELSVKAGADFVKTSTGFSTGGATAEDIALMRKTVGPNVGVKASGGVRTREDAEKMVAAGASRVGASASVAIVLNDAKGATDNY | Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate. | C3P786 |
A4X4N7 | IF2_SALTO | Translation initiation factor IF-2 | Salinispora | MAGKARVHELAKELGVESKTVLAKLKEMGEFVKSASSTVEAPVARRLRNAFVNNTGSPAPAAPPAATPPTPTPTPTPPRTPTPAPPPGGPRVTAKPMPPRRPGAPTPGPKPKGPVPGPPQSATPAAKPASAHDIEVAAAEARAAALKAEQEAAVKAAQAARQQQRDNVRREPPTEGGPRPGPRPGPGAMPPRPGSPAAGRSGGPTPGPGPRSGGRPPARGAGNNPFGIQGGQQRPPAAGAGGPRPSPASMPPRPSPASMPPRPSPASMPSQRPGRPGGPGSGRPGAGAGRPGGGGGGGGGYRGGGGGGGGGYRGGPGGGG... | One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. | A4X4N7 |
P17867 | CISA_BACSU | Stage IV sporulation protein CA | Bacillus | MIAIYVRVSTEEQAIKGSSIDSQIEACIKKAGTKDVLKYADEGFSGELLERPALNRLREDASKGLISQVICYDPDRLSRKLMNQLIIDDELRKRNIPLIFVNGEYANSPEGQLFFAMRGAISEFEKAKIKERTSSGRLQKMKKGMIIKDSKLYGYKFVKEKRTLEILEEEAKIIRMIFNYFTDHKSPFFGRVNGIALHLTQMGVKTKKGAKVWHRQVVRQILMNSSYKGEHRQYKYDTEGSYVSKQAGNKSIIKIRPEEEQITVTIPAIVPAEQWDYAQELLGQSKRKHLSISPHNYLLSGLVRCGKCGNTMTGKKRKSH... | Putative site-specific recombinase having a very important role in sporulation. It probably plays a role in the recombination of SpoIIIC and SpoIVCB to form sigma K factor. | P17867 |
A5W9A9 | SSRP_PSEP1 | Small protein B | Pseudomonas | MAKQKKHPTGTIAQNKKARHDYFIEHKFEAGLVLSGWEVKSLRAGKAHLTDSYVLLKDGEAWLFGSHITPLTTASTHVIADPTRTRKLLLNKRELERVEAAVAQKGYTCVALALYWSKHLIKCEIALGKGKKEFDKRDTMRERDSNRELQRAVRNKGKEE | Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemb... | A5W9A9 |
Q5U1X0 | TAF11_RAT | Transcription initiation factor TFIID 28 kDa subunit | Rattus | MDNLGESPTDKAGEPGESEETRATPGAPVSADTEGIPEETDQVGDADSKEAAAEESELKSQDVSDVTAAEREDPSLLTPAAKKLKLDTKDKKEKKQKVDEDEIQKMQILVSSFSEEQLNRYEMYRRSAFPKAAIKRLIQSITGTSVSQNVVIAMSGISKVFVGEVVEEALDVCEKWGEMPPLQPKHMREAVRRLKSKGQIPNSKHKKITFF | The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription. TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC). The TFIID c... | Q5U1X0 |
Q2YLI7 | PROA_BRUA2 | Glutamyl-gamma-semialdehyde dehydrogenase | Brucella | MTKDIAQVMAEVGRKAKAAAAPLSIATSEQKNKALNAAADAILEARADILEANRLDLANAEKNGMAASFVDRLTLNEARIDAIAEGIRAIATLPDPVGEVIAEWDRPNGLHIERVRTPLGVIGVIYESRPNVTADAGALCLKAGNAVILRGGSDSAHSSAAIHKALVKGLEAANLPADAIQIVPVTDRAAVGEMLKGLGGAIDVIVPRGGKSLVARVQSEARVPVFAHLEGICHLYIDKSADLDMARRIALDAKMRRTGICGAAETLLVDRAVASTHLAPILGDLAAGGCEIRGSAEVLALYPAAKPATEEDWSTEYLDA... | Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. | Q2YLI7 |
P69686 | PSBD_TOBAC | Photosystem Q(A) protein | Nicotiana | MTIALGKFTKDENDLFDIMDDWLRRDRFVFVGWSGLLLFPCAYFAVGGWFTGTTFVTSWYTHGLASSYLEGCNFLTAAVSTPANSLAHSLLLLWGPEAQGDFTRWCQLGGLWTFVALHGAFGLIGFMLRQFELARSVQLRPYNAIAFSGPIAVFVSVFLIYPLGQSGWFFAPSFGVAAIFRFILFFQGFHNWTLNPFHMMGVAGVLGAALLCAIHGATVENTLFEDGDGANTFRAFNPTQAEETYSMVTANRFWSQIFGVAFSNKRWLHFFMLFVPVTGLWMSALGVVGLALNLRAYDFVSQEIRAAEDPEFETFYTKNI... | Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photoni... | P69686 |
P33536 | RBL_OSMCI | Ribulose bisphosphate carboxylase large chain | Osmundastrum | GIGFKAGVKDYRLTHYTPDYETKDTDILAAFRMTPQPGVPAEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYDIEPVAGEENQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRSEDSRIPPAYSKTFIGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFVAEALFKAQAETGEIKGHYSNATAGTCEEMMKRAVFARESGAPIVMHDYSTGGFTANTSLAFYCRDNGLLLHIHRAMHAVIDRQRNHGIHFRVLAKALRMSGGDHIHSG... | RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site. | P33536 |
P15241 | K2M2_SHEEP | Keratin, type II microfibrillar, component 7C | Ovis | CGFSTVGSGFGSRAFSCVSACGPRPGRCCITAAPYRGISCYRGLTGGFGSRSVCGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKCLNNRFAAFIDKVRFLEQQNKLLETKLQFFQNRQCCESNLEPLFEGYIETLRREAECVEADSGRLSSELNHVQEVLEGYKKKYEQEVALRATAENEFVALKKDVDCAYVRKSDLEANSEALIQEIDFLRRLYQEEIRVLQANISDTSVIVKMDNSRDLNMDCIVAEIKAQYDDIASRSRAEAESWYRSKCEEIKATVIRHGETLRR... | Wool microfibrillar keratin. | P15241 |
A6TCG5 | GLYA_KLEP7 | Serine hydroxymethyltransferase | Klebsiella | MLKREMNIADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGGCEYVDVVEQLAIDRAKELFGADYANVQPHSGSQANFAVYTALLQPGDTVLGMNLAQGGHLTHGSPVNFSGKLYNIIPYGIDESGKIDYDDMAKQAQEHKPKMIIGGFSAYSGIVDWAKMREIADSIGAYLFVDMAHVAGLIAAGVYPNPVPHAHVVTTTTHKTLAGPRGGLILAKGGSEELYKKLNSAVFPSAQGGPLMHVIAAKAVALKEAMEPEFKVYQQQVAKNAKAMVEVFLNRGYKVVSGGTENHLFL... | Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent a... | A6TCG5 |
P28808 | LCRF_YERPE | Thermoregulatory protein LcrF | Yersinia | MASLEIIKLEWVTPIFKVVEHSQDGLYILLQGQISWQSSGQTYDLDEGNMLFLRRGSYAVRCGTKEPCQLLWIPLPGSFLSTFLHRFGSLLSEIGRDNSTPKPLLIFNISPILSQSIQNLCAILERSDFPSVLTQLRIEELLLLLAFSSQGTLFLSALRHLGNRPEERLQKFMEENYLQGWKLSKFAREFGMGLTTFKELFGTVYGISPRAWISERRILYAHQLLLNGKMSIVDIAMEAGFSSQSYFTQSYRRRFGCTPSQARLTKIATTG | Transcriptional activator of the thermally regulated virulent yopE gene. LcrF activity could be modulated by the interaction with an inducer molecule serving as a temperature messenger. The availability of the messenger would in turn be controlled by a temperature-responsive process serving as a cellular thermometer. | P28808 |
P0C0N1 | OTC_STAES | Ornithine carbamoyltransferase | Staphylococcus | MKNLRNRSFLTLLDFSRQEVEFLLTLSEDLKRAKYIGTEKPMLKNKNIALLFEKDSTRTRCAFEVAAHDQGAHVTYLGPTGSQMGKKETAKDTARVLGGMYDGIEYRGFSQRTVETLAQYSGVPVWNGLTDEDHPTQVLADFLTAKEVLKKEYADINFTYVGDGRNNVANALMQGAAIMGMNFHLVCPKELNPTEELLNRCERIATENGGNILITDDIDKGVKDSDVIYTDVWVSMGEPDEVWQERLKLLKPYQVNQALLEKTGNPNVIFEHCLPSFHNAETKIGQQIYEKYGISEMEVTDDVFESKASVVFQEAENRMH... | Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | P0C0N1 |
Q6LQC0 | HMUV_PHOPR | Hemin import ATP-binding protein HmuV | Photobacterium | MTFGPQPNSLTPLINNQICKKKVAIHAQGLNLILGGKTLLDNFDIDINAGEVTALLGPNGAGKSSLLKVLCGEIEATGSIEFFGQNRKQWSAKALAKHLGVLPQHSTLNFAFLAHEVVELGGLPLELSNIQTQQITQEKMALVDVCDLSHRLYPSLSGGEKQRVHFARILTQVSQAGDQCVLMLDEPTSALDLAHQHRTLQVAKELASNGAAVIIVLHDLNLAAQYADRLVIVNHGLIQADGTPWQALQPDIIERVYGWPVYISSHPTGDFPVILSH | Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system. | Q6LQC0 |
Q21C20 | ISPG_RHOPB | 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase | Rhodopseudomonas | MNKLENPLSHDVAGPAPRHKTTQVMVGDVAVGGGAPIVVQSMTNTDTADVAGTVEQVAALTRAGSELVRITVDREEAAAAVPHIRDALRKRGITTPLIGDFHYIGHKLLADYPACAEALDKYRINPGNVGFKNKRDSQFADIVEIAIKNNKAVRIGANWGSLDQELLTKLMDENAVSAKPRDVRAVTREAMVQSALLSAARAEEIGLAKNKMVLSAKVSAVQDLIAVYQDLASRSDYAIHLGLTEAGMGSKGIVASSAALGILLQQGIGDTIRISLTPEPGGDRSLEVQVAQELLQTMGFRTFVPLVAACPGCGRTTSTT... | Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. | Q21C20 |
Q6MBU9 | RIMO_PARUW | Ribosome maturation factor RimO | Candidatus Protochlamydia | MLPILKNQGVKKDQNHIALKNDSCESSSPCFDHEGNKINFISLGCPRNLVDSEVMLGILLKAGYEVAPTLEEADYLVINTCGFLEASRQESMDTVEEVLSQRKKTAKLIVTGCMVQTHSDALKTTFPSIDYLLGSGDVEGILKAVQSTQKGQIISSARSYLEAGEVPRRLSTPKHYAYLKIAEGCRKRCAYCVIPTIKGPLKSKGKEQILKEFNLLLSQGVKEVILIAQDLGDYGKDQGAKKLTALLNLLQSMLEIKQAFWLRLLYLYPDEITDELIALMKSDSRICPYLDMPIQHVNNQILKSMRRATSKEDIIEIITK... | Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12. | Q6MBU9 |
B5FG22 | RS14_ALIFM | 30S ribosomal protein S14 | Aliivibrio | MAKQSMKAREAKRAKLVAKFAEKRAALKVLISDVNASEEERWDAVLKLQALPRDSSASRQRNRCNQTGRPHGYLRKFGLSRIKVREACMKGEIPGLRKASW | Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site. | B5FG22 |
A4XL78 | RLMN_CALS8 | tRNA m2A37 methyltransferase | Caldicellulosiruptor | MKRLIKDFTFDELKKWVEETGEKPFRANQIFEWLYKKNATDVNSFTNIPTQLRKRIEEEFILNSLRVVKYESDGESIKFLLELVDGNAIESVFLPYKYGNAICISTQVGCRMKCAFCASTIGGMIRNLSAGEMVDQIVNIENITKKKISNVVLMGSGEPFDNIENVFKFIDIINSKEGKNIGARHITISTVGIVDGIYKLSEYPKQVNLAISLHAPNNNLRNKLVPMNRKYSIEDILKAVDYYISKTNRRVTFEYALIDGVNDSIECANELAKILSGKLVHVNLIPVNPVNGRNFKKPPKERVKEFYNVLILSGIQVTIR... | Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. | A4XL78 |
B8HX39 | ANMK_CYAP4 | AnhMurNAc kinase | unclassified Cyanothece | MHVIGLISGTSVDGIDAALVDLSGTSLDLQVELLAAHTYPYSEPVRSQIISLCKGEAIPLAELALLDEAIAQEFAQAALEIQQGQPAAELIGSHGQTVYHRPVIGNTPAYTLQLGRGAIIAQQTGLPTITNFRVADTNAGGEGAPLVSRIDICLFSHPQQRRCVQNIGGIANLTYLPPLSDVAQIGVGVQGWDTGPGNSLLDLAVQYLSGGRQAYDDKGNWAAQGTPCQALVEQWLSHPYFEQAPPKSTGRELFGWDYLQTCLRDAEPYHLSAEDFLATLTELTAASIVLNYRQFLPALPDQVLLCGGGVRNHYLKQRLA... | Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall ... | B8HX39 |
P58602 | CPI4_SOLTU | PCPI-23 | Solanum | PVLQVVRDIHGDILTPDSRYIL | Inhibitor of papain (cysteine protease). Does not inhibit trypsin, chymotrypsin nor elastase (serine proteases). May protect the plant by inhibiting proteases of invading organisms. | P58602 |
P0A3S9 | PAL_BRUAB | Outer membrane lipoprotein Omp16 | Brucella | MRRIQSIARSPIAIALFMSLAVAGCASKKNLPNNAGDLGLGAGAATPGSSQDFTVNVGDRIFFDLDSSLIRADAQQTLSKQAQWLQRYPQYSITIEGHADERGTREYNLALGQRRAAATRDFLASRGVPTNRMRTISYGNERPVAVCDADTCWSQNRRAVTVLNGAGR | Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | P0A3S9 |
Q9MAP5 | SBT33_ARATH | Subtilase subfamily 3 member 3 | Arabidopsis | MRSFRSSILLVLLSLITVLNATRARSETESKVHIVYLGEKKHHDPEFVTESHHQMLASLLGSKKDADDSMVYSYRHGFSGFAAKLTKSQAKKIADLPEVVHVIPDGFHELATTRTWEYLGLSSANPKNLLNDTNMGDQVIIGVIDTGVWPESESFNDNGVGPIPRKWKGGCESGENFRSTDCNRKLIGAKYFINGFLAENKGFNTTESRDYISARDFDGHGTHVASIAGGSFVPNVSYKGLAGGTLRGGAPRARIAMYKACWFHEELKGVTCSDSDIMKAIDEAIHDGVDVLSISLVGQIPLNSETDIRDEFATGLFHAV... | Serine protease that plays a role in the control of the establishment of immune priming and systemic induced resistance. | Q9MAP5 |
Q8FK20 | ENTS_ECOL6 | Enterobactin exporter EntS | Escherichia | MNKQSWLLNLSLLKTHPAFRAVFLARFISIVSLGLLGVAVPVQIQMMTHSTWQVGLSVTLTGGAMFVGLMVGGVLADRYERKKVILLARGTCGIGFIGLCLNALLPEPSLLAIYLLGLWDGFFASLGVTALLAATPALVGRENLMQAGAITMLTVRLGSVISPMIGGLLLATGGVAWNYGLAAAGTFITLLPLLSLPALPPPPQPREHPLKSLLAGFRFLLASPLVGGIALLGGLLTMASAVRVLYPALADNWQMSAAQIGFLYAAIPLGAAIGALTSGKLAHSVRPGLLMLLSTLGAFLAIGLFGLMPMWILGVVCLAL... | Component of an export pathway for enterobactin. | Q8FK20 |
C4LEG3 | AROA_TOLAT | 5-enolpyruvylshikimate-3-phosphate synthase | Tolumonas | MNTLTLEPIARVEGTVNLPGSKSVSNRALLLAALARGTTRLTNLLDSDDIRHMLNALKTLGVSYELSANKTECTVHGLGRAFSSSEPVNLFLGNAGTAMRPLCAALCLSNGEFTLTGEPRMEERPIAHLVDALRQAGAHVHYLKKDGYPPLTIEGKGLWGGEVVIDGSVSSQFLTAFLMAAPLASGDVRIRIRGELVSKPYIDITLHIMKQFGVTVEHDDYQVFYVRGNQTYVSPGTFLVEGDASSASYFLAAGAIKGKVRVTGIGKNSIQGDIRFADVLEKMGAKITWGDDFIEAENVGELQAVDLDMNQIPDAAMTIA... | Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | C4LEG3 |
A2CBN5 | MTND_PROM3 | Acireductone dioxygenase (Ni(2+)-requiring) | Prochlorococcus | MSRLSIHPEGNTNATSPAEPLLESDDPAVIKAELAKRGIEFQHWPAKVKLHQNSIESDILAAYAVEIARVQADGRYPTVDAIRITPDHPDREALRQKFLAEHTHAEDEVRFFVEGRGLFCLHIGAEVLQVLCEQNDCINVPAGTRHWFDMGSKPQFCAVRFFDNPEGWIASFTGDAIAERFAKLP | Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine... | A2CBN5 |
Q20EU1 | CEMA_OLTVI | Chloroplast envelope membrane protein | Oltmannsiellopsis | MDSESQLLEGAVEKIGLIPRSIIRTINRFQQQLFPDAVEYFIQEFRVSRSQVLVSLQCLLTLIIIPLFIHFFAKTVFLTPCIEYVWNTYKTDIFLNSYQQEQALTEMRNFEEILYFDLLVQSNEEPVTQEGLPFTFLQHSQGSVDEEKTTAPITAYAVSNMGNPETATIAPQHLHGSVGGKLESEFRFTNPSFVGKNNVTGATTITAAIPLQKKLVDLAQSANKQSIAALTNLFADLLTLFSLIILFIRLKSQIIILKSFLIETFYSLNDTTKSFMLIFSTDLLVGFHSPRGWEIFLDFILSRFGLPHDENIILLFVATF... | May be involved in proton extrusion. Indirectly promotes efficient inorganic carbon uptake into chloroplasts. | Q20EU1 |
Q0IQN6 | DRB8_ORYSJ | dsRNA-binding protein 8 | Oryza sativa | MDMPPTPLPPETANTSPAPNGATAGIRVENCYVFKSRLQEYAQKTGLQTPEYHTFKEGPSHEPVFKSTVVINNTSYDSLPGFFNRKAAEQSAAEVALMEIVKSIPANANIPAVQETGLCKNLLQEYAQKMNYAIPSYICTKSASGLAPFICTVEIGGIQYIGAAARTKKDAEIKAARTALLAIQGQSEGSANGATKYIVVPGKRVGKEVEKRPIETPKPLKVKKGGFKKKWNKRKFMKKDGQAVDVEKDEARVAGDAHDSDVLMQPTVITQEASCGTLFLQPCEEAKRVEAEPPRDIEMVQPDKENQHSDAALVQPDDEA... | Binds double-stranded RNA. | Q0IQN6 |
P85117 | TX1_GRARO | GrTx1 | Grammostola | YCQKWMWTCDSKRKCCEDMVCQLWCKKRL | Inhibits voltage-gated sodium channels Nav1.1/SCN1A (IC(50)=630 nM), Nav1.2/SCN2A (IC(50)=230 nM), Nav1.3/SCN3A (IC(50)=770 nM), Nav1.4/SCN4A (IC(50)=1290 nM), Nav1.6/SCN8A (IC(50)=630 nM), Nav1.7/SCN9A (IC(50)=15.3-1000 nM) and potassium channels Kv11.1/KCNH2 (IC(50)=4.2 uM). | P85117 |
P10901 | FUCO_DICDI | Alpha-L-fucoside fucohydrolase | Dictyostelium | MKMIIIFFILLILNLIKSQQYGPTWDQINSRPLPGWYDDVKFGIFIHFGIYSVPAFANGGYAEWYWWTLKNPSSDGGATQRYHEKEFGANFTYQDFVSRFDCRLFDANEWASIIEKSGAKYVVLTSKHHEGYTLWNSEQSWNWNSVETGPGIDIVGELTKSVKNMGLHMGLYHSLFEWFNPLYLADAETGKNPTTQVYVDEILMKQLKDIVTTYEPELIWADGDWMQLSNYWKSTEFLSWLYTNSSVKDTVIVNDRWGSECRDKNGGFYTGADHFNPYKLQSHKWENCATIGYSYGYDEYEQATDYQNATELIIDLVTTV... | Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. | P10901 |
B0SC03 | TRUA_LEPBA | tRNA-uridine isomerase I | Leptospira | MPNYALLVEYDGTHFNGWQKQKNLPTVQSSIESALGIILRRNPASRLSVAGRTDTGVHALGMVCNFKTEHPIPNFHKLLVSLNALTPTGVSVKNVVEVPSDFHARFSCTGREYIYKLYYSKYESSFVEGRAFWVKGHIDWERVKKQLQVLVGEKDFRSFTKAKSMAGKRAVREILAIQLENLSPEWYQIRIRANGFMHNMVRITVGTLLDIGKGRWESRSIDSILEEKNRTQAGVTLPPDGLYFVRAYYEDHPEIHELYKIPLP | Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | B0SC03 |
P0DL16 | CRVP_NAJMO | Cysteine-rich venom protein mossambin | Naja | NVDFNSESTRRKKKQNEIVDLHNSLRRTVN | Inhibits calcium-activated potassium channels (KCa), voltage-gated potassium channel (Kv), and the calcium release channel/ryanodine receptor (RyR). | P0DL16 |
B7JZP4 | ACCA_RIPO1 | Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha | Rippkaea orientalis | MSKNERRTFLLDFEKPLWELEARINQIRELAEENNVDVSEQIAQLERRAEELRQEIFSTLTPSQRLQLARHPRRPSTLDYIQAIADEWFELHGDRGGYDDPALVGGVARLGGRPVTILGEQKGRDTKDNVARNFGMASPGGYRKAMRLMERANQFNQPIITFIDTPGAWAGVEAEKLGQGEAIAYNLREMFRLDVPIICTVIGEGGSGGALGIGVGDRLLMLEHAVYMVATPEACAAILWKDAKKSPQAAMALKITSSDLKELGIIDEIVPEPSGAAHSKPLEAANLLKQTLIDTIDELSSLSPEQRRKLRYQKYRQIGV... | Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | B7JZP4 |
Q3ZXS0 | NUOB_DEHMC | NDH-1 subunit B | Dehalococcoides | MELNFEKPLSLLTLDEIDQQEGGVIQSFRTGHTSPYPDPADWLNGEEPPPGVFITSVEKVLNWSRHYSLWPVMFGLACCAIEMMCMAASRWDLARFGMDIFRASPRQADLMIVAGTLTWKMAPWLKRIYDQMPEPKWVLAMGACGTSGGLFRDSYSVVPGFNLVVPVDVYVPGCPPRPEALMRAIMDIHEKIDKTRILKR | NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are t... | Q3ZXS0 |
Q256C2 | CLPP1_CHLFF | Endopeptidase Clp 1 | Chlamydia | MTLVPYVVEDTGRGERAMDIYSRLLKDRIVMIGQEITEPLANTVIAQLLFLMSEDPQKDIKVFINSPGGYITAGLAIYDTIRFLGCDVNTYCIGQAASMGALLLSAGTKGKRYALPHSRMMIHQPSGGIIGTSADIQLQAAEILTLKKHLANILSECTGQPVEKIIEDSERDFFMGAEDAISYGLIDKVVSSAKDTKDKDTIS | Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. | Q256C2 |
Q5FA58 | RIMM_NEIG1 | Ribosome maturation factor RimM | Neisseria | MTDTQNRVAMGYIKGVFGIKGWLKIAANTEYSDSLLDYPEWHLAKDGKTVSVTLEAGKVVNGELQVKFEGIDDRDSAFSLRGYTIEIPREAFAPTEEDEYYWADLVGMTVVNKDDTVLGKVSNLMETGANDVLMIDGEHGQILIPFVSQYIETVDTGSKTITADWGLDY | An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosoma... | Q5FA58 |
B8DZY2 | RL25_DICTD | General stress protein CTC | Dictyoglomus | MEITEIKVKKRDKIGKQFAKKYRRSNLIPGVVYGAHLKENIHILVEKKDLWSLIKKGHAKEQHLLRLIIENGENTITENAILQDLQIDPIKDEFLHVDFHAITLEELVDVYVPILLVGEAKGIKQGGILQHGVEEILIRALPLDVPPHIEVDITDLEIGESITVGDLKFPENIKVLTPLDEVVVGIIPPKGYTEEVTTGEAQTESQT | This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. | B8DZY2 |
Q8BJ03 | COX15_MOUSE | Cytochrome c oxidase assembly protein COX15 homolog | Mus | MQRLLLPSLRALTGSRNVGLLVPRVASRTQCGSSCGSQRPLRPGQYSTITEVALQSGKGTVSLPSRAAERAVGRWLLVCSGTVAGAVILGGVTRLTESGLSMVDWHLIKEMKPPTSQEEWEAEFQKYQQFPEFKILNHDMTLAEFKFIWYMEYSHRMWGRAVGLAYILPAAYFWRKGWLNRGMKGRVLALCGLVCFQGLLGWYMVKSGLEEKPESYDIPRVSQYRLAAHLGSALVLYCASLWTSLSLLLPQHKLPETRQLLWLRRFAGGTAGLVFLTALSGAFVAGLDAGLVYNSFPKMGESWIPEDLLTFSPVLKNVFE... | May be involved in the biosynthesis of heme A. | Q8BJ03 |
C1KVD5 | NADD_LISMC | Nicotinate mononucleotide adenylyltransferase | Listeria | MKHKVGILGGTFDPPHLAHLRMAEEAKKQLGLEKILFLPNKIPPHKHISGMASSDERVEMLQLMIEGIDSFEIDTRELMRAGKSYTYDTMRDMISEQPDTDFYFIIGGDMVEYLPKWYHIDDLVKMVTFVGVNRPSYQTEVPYDIVKINMPETTISSTEIRNNIENASTFLPEKVWSYIKEHQLYGKK | Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | C1KVD5 |
Q92AH4 | PYRK_LISIN | Dihydroorotate oxidase B, electron transfer subunit | Listeria | MLQTEMKVIQQTEIADKVYELILSGECVADMSPGQFLMLKPSRSDLLMRRPISICSYDKTAKTCILLYRVEGDGTKDFSSLSKGDSIDVLGPLGKGFDLNTIPAPKTALLIGGGIGVPPMYQLGKELADKGVQVTFVNGFQSEKDSFYEKEMTEYGTVHIATVDGSYGTQGFVTDITKNFPEEPDVIYSCGPKAMLQAVKASFPETKTYLSLEERMACGIGACYACVCPKAGDTKKQFKVCEDGPVFRADEVSL | Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). | Q92AH4 |
P58182 | O12D2_HUMAN | Olfactory receptor OR6-28 | Homo | MLNTTSVTEFLLLGVTDIQELQPFLFVVFLTIYFISVTGNGAVLMIVISDPRLHSLMYFFLGNLSYLDICYSTVTLPKMLQNFLSTHKAISFLGCISQLHFFHSLGSTESMLFAVMAFDLSVAICKPLRYTVIMNPQLCTQMAITIWVIGFFHALLHSVMTSRLNFCGSNRIHHFLCDIKPLLKLACGNTELNQWLLSTVTGTIAMGPFFLTLLSYFYIITYLFFKTRSCSMLCKALSTCASHFMVVILFYAPVLFTYIHPALESFMDQDRIVAIMYTVVTPVLNPLIYTLRNKEVKGALGRVIRRL | Odorant receptor. | P58182 |
Q22RG7 | H34_TETTS | Minor histone H3 variant | Tetrahymena | MARTKQTARKSTSIKAPRKQLAAKAARKSAPISGGIKKPHKFRPGTVALREIRKYQKTTDLLIRKLPFQRLVRDIAMEMKSDIRFQSQAILALQEAAEAYLVGLFEDTNLCAIHARRVTIMTKDLHLARRIRGERF | Macronuclear replacement variant which replaces conventional H3 in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replicati... | Q22RG7 |
B2JFK6 | ACPS_PARP8 | 4'-phosphopantetheinyl transferase AcpS | Paraburkholderia | MAIYGIGTDIVQVSRVAAVMQRTNGRFAEKVLGPDELRVYHARHARSQARGLAFLATRFSVKEAFSKAIGLGMRWPMTWRALQTLNEPSGRPTCVASGELADWLAERGITSRVTLSDERDYAVSFVIAETPDTAD | Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. | B2JFK6 |
Q884C8 | SYE_PSESM | Glutamyl-tRNA synthetase | Pseudomonas | MTTVRTRIAPSPTGDPHVGTAYIALFNYCFAKQHGGEFILRIEDTDQLRSTRESEQQIFDALRWLGIEWSEGPDVGGPHGPYRQSERGDIYQKYAQQLVELGHAFPCFCTAEELDEMRAEQQAKGETPRYDGRALLLSKEEVQRRLDAGEPHVIRMKVPTEGVCVVPDMLRGEVEIPWDRMDMQVLMKTDGLPTYFLANVVDDHLMGITHVLRGEEWLPSAPKLILLYEYFGWDKPQLCYMPLLRNPDKSKLSKRKNPTSVTFYERMGFMPEAMLNYLGRMGWSMPDEREKFSLQEMVDHFDLSRVSLGGPIFDIEKLSW... | Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | Q884C8 |
C0QWN8 | ACKA_BRAHW | Acetokinase | Brachyspira | MNVLVINSGSSSIKYQLFAMPEAKVLAKGLLEKIGEEISALKHTAVEKGKEKKIEQKVADHKAGMSLIFSLLTDKEVGVIADMNEISAVGHRVVHGGEAFNKSILITDEAIKAIEACCDIAPLHNPAGLQGISACKEILKDVKMVGVFDTSFHQTIPDYAYMYAVPHEWYDKYKIRRYGFHGTSHKYVYGEFCKVTNKPNANVIVCHLGNGASVTAVKNGESIDTSMGLTPLEGLVMGTRSGDMDPAVPTFVMAKENLSAKEMDNILNKKSGLLGVSGVSNDMRNLEEAAKTNPKAELAITMFCYRVKKYIGAYMAALGH... | Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. | C0QWN8 |
Q32I48 | UVRB_SHIDS | Excinuclease ABC subunit B | Shigella | MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLHLTVGMIIDQRAILRRLAELQYARNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFDEEVERLSLFDPLTGQIVSTIPRFTIYPKTHYVTPRERIVQAMEEIKEELAARRKVLLENNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGE... | The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP bindi... | Q32I48 |
Q9V4I1 | CP9B2_DROME | CYPIXB2 | Sophophora | MALIEICLALVVIGYLIYKWSTATFKTFEERKLYFEKPYPFVGNMAAAALQKSSFQRQLTEFYERTRQHKLVGFFNMRTPMITLNDPELIKKVCVKDFDHFPNHQPFITSNDRLFNDMLSVMRDQRWKHMRNTLTPVFTAAKMRNMFTLMNESFAECLQHLDSSSKTLPGRKGFEVDMKVMCNKLSNDIIATTAFGLKVNSYDNPKNEFYEIGQSLVFSRGLQFFKFMLSTLVPKLFSLLKLTIFDSAKVDYFARLVVEAMQYREKHNITRPDMIQLLMEAKNESEDKWTDDEIVAQCFIFFFAAFENNSNLICTTTYEL... | May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides. | Q9V4I1 |
Q981J9 | CH605_RHILO | Chaperonin-60 5 | Mesorhizobium | MAAKDVKFSRDARERMLRGVNILADAVKVTLGPKGRNVVIDKSFGAPRITKDGVTVAKEIELEDKFENMGAQMVREVASKTNDIAGDGTTTATVLAQSIVQEGHKAVAAGMNPMDLKRGIDLAVADVVATLIKNAKKIKTSEEVAQVGTIAGNGDSSVGSMIAEAMQKVGNEGVITVEEAKTAETELEVVEGMQFDRGYLSPYFVTNADKMVADLEDAYILLHEKKLSNLQAMLPILEAVVQTSKPLVIISEDVEGEALATLVVNKLRGGLKIAAVKAPGFGDRRKAMLEDIAILTGGQVISEDLGIKLENVGLNMLGRA... | Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. | Q981J9 |
Q9MUS0 | PSBK_MESVI | Photosystem II reaction center protein K | Mesostigma | MNIGFDMILAKLPEAYAMFDPLVDVLPVIPLLFLLLAFVWQASVSFR | One of the components of the core complex of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, a... | Q9MUS0 |
P05630 | ATPD_BOVIN | F-ATPase delta subunit | Bos | MLPSALLRRPGLGRLVRQVRLYAEAAAAQAPAAGPGQMSFTFASPTQVFFNSANVRQVDVPTQTGAFGILAAHVPTLQVLRPGLVVVHAEDGTTSKYFVSSGSVTVNADSSVQLLAEEAVTLDMLDLGAAKANLEKAQSELLGAADEATRAEIQIRIEANEALVKALE | Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous ca... | P05630 |
Q165E3 | GLGC_ROSDO | ADP-glucose synthase | Roseobacter | MNREEQRLAQQTMAFVLAGGRGSRLYELTDRRAKPAMYFGGKSRIIDFPLSNAVNSGIRRIGVATQYKAHSLIRHLQRGWSFFRAERNESLDILPASQQMNDENWYKGTADAVAQNKDIIEGYGPKYIIILAGDHIYKQDYAEMIRHHVESGADVTVGCIEVPRMEASGFGVMKVDTEDRILDFIEKPGDPPAMPGHPDQALASMGIYVFETEYLFKIMEECAAVPGYSHDFGGDIIPTIVRGGKAVAHPFSRSCVRTVNEEAPYWRDVGTVDAFWQANLDLTDFKPALDLYDTEWPIWTYSELTAPAKFIHNEEGRRGS... | Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc. | Q165E3 |
B1Y222 | MNMC_LEPCP | FAD-dependent cmnm(5)s(2)U34 oxidoreductase | Leptothrix | MRRSNPITPARLGRSAEGLPFSEDFGAPYHPSAGALAQAEQVFLRGTDLPARWAGQARHVILETGFGLGHNFLATWAAWRRDPRRCERLVYLAIDKHPPAPADLADVHRDSPLADLAAQLIAAWPLATPDLHLLDFEGGRVQLMLALGDIHDVLPGLQAEAHSLYLDGFVPARNPAMWSADVFKRIARLAAPGAMAASGHADSAVRDGLVRQGFEVRATGADATVARYAPRFQPEPPRGWRWPHAAAREALVIGGGLAGCAVAQALALQGWRSTVIDRQAGPAQETSGNAGGLMHGIFNAPDSPHARWFRAAAMHTARNA... | Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s... | B1Y222 |
Q1D5J5 | NHAA1_MYXXD | Sodium/proton antiporter NhaA 1 | Myxococcus | MAQTPPTSEARPRPPVPTLFRVALAPIQAFFRLEAASGILLALCAVAAMVWANSPWAATYSAVFDARMTVGLAGVHAGFTIREFINDGLMTLFFFVVGMEIKRELSSGELRTFSRAVLPLIAAMGGMIVPAALYAAFNQGTPAQAGWAIPMATDIAFSIGCLTLVKTRVSHGLVVFLTALAIFDDIGGILVIALFYGSGLHVSWLVGALGVLAVLACLNHFQVRNGVAYALAGAALWYTMHHGGIHATLSGVVLGLFMPARPLRPGRHVLEELRLYVDRALQTAMDEATRGAQILYLEERLEELEPPLNRFVHLWHVPVA... | Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. | Q1D5J5 |
Q9FJ74 | WAXS3_ARATH | Wax synthase 3 | Arabidopsis | MEEELKNFIKLWISAIISISYCYYLSTGIKAGVFRLLSVLPVCALFLVFPLFFSYVHFSGCMAFFLSWLANFKLILFSFDQGPLSPLPRTLSRFICITCFPIKPQQNPNIQNYKIPIWLFAIKVVIFVVLLQMYEYKQYLSPALLLVFNSLHIFLELEIVFMLVKALVFITLGCDLEPQSNEPYLATSLQDFWGRRWNLMVPAILRPAVYLPARRMACRKVNSDQAMFLGVFAAFLVSGAVHEMLFFYLTREVPTGEVTWFFLLHGVCTVAEVAVKKSTFVRRWWRVSPTVSRLLTVGFVVVTSGWFFFPLIRSGIIERL... | Catalyzes the final step in the synthesis of long-chain linear esters (waxes). | Q9FJ74 |
P12018 | VPREB_HUMAN | V(pre)B protein | Homo | MSWAPVLLMLFVYCTGCGPQPVLHQPPAMSSALGTTIRLTCTLRNDHDIGVYSVYWYQQRPGHPPRFLLRYFSQSDKSQGPQVPPRFSGSKDVARNRGYLSISELQPEDEAMYYCAMGARSSEKEEREREWEEEMEPTAARTRVP | Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells. This complex presumably regulates Ig gene rearrangements in the early steps of B-cell differentiation. | P12018 |
A2SPS3 | COFD_METLZ | 2-phospho-L-lactate transferase | Methanocorpusculum | MITVFSGGTGTPKLIRGLRQILHDHEITVVVNTAEDLWMSGLYVSPDIDTVQYLFSGLLNTDSWWGIRGDSFETFHAMEKLGYTELLPLGDKDRATNIARAEFLRQGMTLTEATEKIAKGYGVSARILPMSDQNVASYVVCEDDSLMHYQEYWVGKRGNVNIKGVVRKTTDGLPLKTTPEVISAIEESDGVIIGPSNPVTSIGPILECAGVREALQNTFTAAVSPFIGNRPVSGPAAALMKAWGYESTSYGTWQVYKDVVDLFIQDVRDTAIEVPGAHRLDTMMTNEKKAESLAWDLLSYFPRK | Catalyzes the transfer of the 2-phospholactate moiety from (2S)-lactyl-2-diphospho-5'-guanosine to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of oxidized coenzyme F420-0 and GMP. | A2SPS3 |
Q4JBV4 | LIPA_SULAC | Sulfur insertion protein LipA | Sulfolobus | MKSEVVVRINENFKKLSRIVSEKGISTVCEEALCPNIMECWGSGTATFMIMGDICTRGCRFCYVKKGKPVLLDHEEPIKVAEAVREMGLDYVVITSVDRDDLADGGASHFSQVVKAVKEMNPDVIVEVLTPDFMGNKELVEKVIGSGVDVFAHNVETVRSLTPLVRDARASYEQSLRVLSYAKNVVKKSSILLGLGESLEEVVETMKDLRNVGVDILVLSQYMRPSIKQLEVKKRYNMEEYKELEKIAYSLGFSYVVALPHARTSYRAKEAYLRAMANVKNNNRWS | Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Q4JBV4 |
B1KZM3 | ERA_CLOBM | GTPase Era | Clostridium | MFKSGFVTIVGRPNVGKSTLLNAIMKEKLSIVSCRPQTTRNNIQTILTEDNYQLVFVDTPGIHKPKHKLGEYMVKSASDAMKDVDLVLFLINPDEKPGRGDLFIIEQLKEVKVPVFLVLNKIDENPQEKVAETLKTYSELMEFEEIIPISALKGKNIDLLKELMFKYIPEGPQYYPEDMIIDQNERFIVAEIVREKALRLLSEEVPHGIAVEILQMKRNEKGTYHIEGNILCEKNSHKPIIIGKGGSKLKKISQYARQDIEAFLQSKVYIRLWVKVKEEWRDNQSLLKELGYKNMK | An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | B1KZM3 |
Q08465 | YNG1_YEAST | ING1 homolog 1 | Saccharomyces | MEHLANENSDSDIRYSFLSTLDHLPCELIRSLRLMQTIDLFKNEEDEPGMERACRDLLLVATYINDLVDDQIHFLKQHKKELEIQKSVTKNFNSSLENIKSKLTLEEPGAYKEPKLLLKINLKKAKSRERKESITSPTIGINQGDVTEGNNNQEEVYCFCRNVSYGPMVACDNPACPFEWFHYGCVGLKQAPKGKWYCSKDCKEIANQRSKSKRQKRRK | Histone-binding component of the NuA3 histone acetyltransferase complex, that acetylates Lys-14 of histone H3. Recruitment of NuA3 to nucleosomes requires methylated histone H3. In conjunction with the FACT complex, NuA3 may be involved in transcriptional regulation. YNG1 is required for the HAT activity of NuA3 but no... | Q08465 |
C0R2E2 | PURA_BRAHW | IMP--aspartate ligase | Brachyspira | MASVIIVGTQWGDEGKGKIVDYLAENCEYVVRSQGGSNAGHTVVVDNIKYKLRLLPSGILHKDKVCVIGNGVVIEPKVFLSEIDSLIEKKVNISNLKISDRAHVLMPYHKILDELQEEDLGENKLGTTKNGIGPCYMDKSSRLGIRIVDLMNKETFAKKLKFNVELKNKLLKKLYNHDGVNYDELLKEYLGYAEKLRPFVADTTTILNKAIKEKKNILFEGAQATMLDLDHGTYPFVTSSYPAAGGACTGSGVGPRKIDNVIGVVKAYATRVGEGPFPSELFDDVGQFIRDKGGEYGTVTGRARRCGWLDACVVKYASYV... | Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. | C0R2E2 |
P54997 | DSZB_RHOSG | Dibenzothiophene desulfurization enzyme B | Rhodococcus | MTSRVDPANPGSELDSAIRDTLTYSNCPVPNALLTASESGFLDAAGIELDVLSGQQGTVHFTYDQPAYTRFGGEIPPLLSEGLRAPGRTRLLGITPLLGRQGFFVRDDSPITAAADLAGRRIGVSASAIRILRGQLGDYLELDPWRQTLVALGSWEARALLHTLEHGELGVDDVELVPISSPGVDVPAEQLEESATVKGADLFPDVARGQAAVLASGDVDALYSWLPWAGELQATGARPVVDLGLDERNAYASVWTVSSGLVRQRPGLVQRLVDAAVDAGLWARDHSDAVTSLHAANLGVSTGAVGQGFGADFQQRLVPR... | Catalyzes the third and final step of the '4S' desulfurization pathway that removes covalently bound sulfur from dibenzothiophene (DBT) without breaking carbon-carbon bonds. Oxidizes 2-(2'-hydroxyphenyl)benzene sulphinate (HBPS) to 2-hydroxybiphenyl (HBP) plus sulfite . The rate-limiting step of the '4S' desulfurizatio... | P54997 |
Q39255 | SKP1A_ARATH | UFO-binding protein 1 | Arabidopsis | MSAKKIVLKSSDGESFEVEEAVALESQTIAHMVEDDCVDNGVPLPNVTSKILAKVIEYCKRHVEAAASKAEAVEGAATSDDDLKAWDADFMKIDQATLFELILAANYLNIKNLLDLTCQTVADMIKGKTPEEIRTTFNIKNDFTPEEEEEVRRENQWAFE | Involved in ubiquitination and subsequent proteasomal degradation of target proteins. Together with CUL1, RBX1 and a F-box protein, it forms a SCF E3 ubiquitin ligase complex. The functional specificity of this complex depends on the type of F-box protein. In the SCF complex, it serves as an adapter that links the F-bo... | Q39255 |
Q10198 | NDC80_SCHPO | NMS complex subunit ndc80 | Schizosaccharomyces | MQDSSSYARRYSQAPSSSNLRTTTFGFNGLGTSRTSLAPQRTLVNARQSIDPDGLSSRVLTPTMRPSLAPNTRRSSVRVSNASFISQTPNITSIKDPRPLSDRRYQQECATQVVNYLLESGFSQPLGLNNRFMPSTREFAAIFKHLYNKLDPNFRFGARYEEDVTTCLKALNYPFLDSISRSRLVAIGSPHVWPAILGMLHWVVSLIQCTEKAVAMVYTVEQNSLDDHLVDKVLFDYLVRTYHLYLDESPEESEPEKELKATFNQQNQDLYNQTEALKSTNEELINQIKSAEELDSAIQVLEERYRTMQRDEVKFQSAMS... | Acts as a component of the NMS (Ndc80-MIND-Spc7) super complex which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cycle. Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activ... | Q10198 |
A0T0H9 | RK4_PHATC | 50S ribosomal protein L4, chloroplastic | Phaeodactylum | MTIQKFITYTPLDLNGKQLNFNHELKLNILETSGNYLVHKDLIRHFGSQRQATSSSKTRSEVRGGGRKPWRQKGTGKARAGSNRSPLWKGGGVIFGPKPKKISLKLNKKERQLALQTLIYNKKNNILIIENLETGMTEPKTKAFVKICQDCQINLEQKVLLVVTDKTSVLKLATQNLKNVELLAASSLNTLSILKARQIILTSAAINHIKESYCD | Probably binds the 23S rRNA. | A0T0H9 |
A5CX29 | RNH_VESOH | Ribonuclease H | Candidatus Vesicomyosocius | MMNRIVIYTDGGCRCNTGIGGWGVWLKYGDYDKKLKGNEKKTTNNRMELTATIKALEEIKSNQIGIDLFTDSKYVITGINEWMKNWKVKNWETSKKRPVKNVDLWQRLDVLNKQHDVIWYWVKSHSNNKGNDIADELANLAMDKISLS | Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | A5CX29 |
P65861 | CRTB_MYCBO | Phytoene synthase | Mycobacterium tuberculosis complex | MTEIEQAYRITESITRTAARNFYYGIRLLPREKRAALSAVYALGRRIDDVADGELAPETKITELDAIRKSLDNIDDSSDPVLVALADAARRFPVPIAMFAELIDGARMEIDWTGCRDFDELIVYCRRGAGTIGKLCLSIFGPVSTATSRYAEQLGIALQQTNILRDVREDFLNGRIYLPRDELDRLGVRLRLDDTGALDDPDGRLAALLRFSADRAADWYSLGLRLIPHLDRRSAACCAAMSGIYRRQLALIRASPAVVYDRRISLSGLKKAQVAAAALASSVTCGPAHGPLPADLGSHPSH | Involved in the biosynthesis of carotenoids. Catalyzes the condensation of two molecules of geranylgeranyl diphosphate (GGPP) to give prephytoene diphosphate (PPPP) and the subsequent rearrangement of the cyclopropylcarbinyl intermediate to yield phytoene (Probable). | P65861 |
A1S1K8 | AROE_SHEAM | Shikimate dehydrogenase (NADP(+)) | Shewanella | MTDRFAVFGNPISHSKSPQIHAMFAKETGQTLTYEAILAPLDGFAEAVTAFMAAGGCGANVTVPFKEQAFTLCDELSDDARIAGAVNTLIKLPDGRLRGDNTDGMGLVADLIRHGVELNNKRVLLVGAGGAARGALLPLVRAGAKLTISNRTLSKAEALAALCPKVNVEVISGSHIRSPFDVIINSTSASLSGDLPVIAANAIDNQTVCYDMMYGAKPTVFNEWARSLGAKICIDGLGMLVGQAAESFYLWRRVRPNAAPVLQTLRQSLISGV | Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | A1S1K8 |
Q31AD1 | TRHO_PROM9 | tRNA hydroxylation protein O | Prochlorococcus | MKGKNYKIVSLYSFFPFQENLIIDLKSKLLEIGYENDLSGLLIFASEGINGTICAEKNVIDIVINLLNKYADNRNLNIKVNFSKKKVFKKLKIKIKKEIVTMGVPEINPSENNGTYIDSANWNKLIKNQNTIVIDTRNHYEVSVGTFQNSINPNTRNFSEFPKWVDDQLDTHLENKESTNIAMFCTGGIRCEKATSLLKKKGYKNIYHLQGGILQYLDDIPKEKNLFEGECYVFDKRVALDQELEKGSYSICHACGMPVSIQDQERKEYRKGIQCHFCIDQFSDDDRKRFEERQKQIDRLKVGNHKIFKD | Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs. | Q31AD1 |
P04816 | LIVK_ECOLI | Leucine-specific-binding protein | Escherichia | MKRNAKTIIAGMIALAISHTAMADDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVAVANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGLDSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEKDFSALIARLKKENIDFVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVGNASLSNIAGDAAEGMLVTMPKRYDQDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATALERTGSD... | This protein is a component of the leucine-specific transport system, which is one of the two periplasmic binding protein-dependent transport systems of the high-affinity transport of the branched-chain amino acids in E.coli. | P04816 |
A9IW04 | RS5_BART1 | 30S ribosomal protein S5 | Bartonella | MAQKERGEREERDNEFVDRLVHINRVAKVVKGGRRFGFAALVVVGDQKGRVGFGHGKAREVPEAVRKATESAKRGMIYVPLRSGRTLHHDLEGRHGAGRVLLRSASAGTGIIAGGPMRAIFEALGMQDVVAKSLGSSNPYNMVRATFDALKHQMHPRDIAAQRGIKYSTLQARRRHLVDVEG | Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. | A9IW04 |
Q5YTM8 | RPOZ_NOCFA | Transcriptase subunit omega | Nocardia | MSDTKTAPAYDTPIGLTNPPIDELLERTSSKYALVIYAAKRARQINDYYNQLGDGILEYVGPLVEPGLQEKPLSVALREIHADLLEHSEGE | Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | Q5YTM8 |
Q52873 | TRA5_RHIME | Transposase for insertion sequence element ISRM5 | Sinorhizobium | MTKTEGKTASAAVKDILLSNPDGLREVIRTVMQEVLEAEMDEALGAAKGERTPERLGYRSGHYGRTLITRVGKLELRVPQDRSGHFSTELFERYQRSERALVATLAEMYVQGVSTRKVKAITEELCGHAFSASSISAINKRLDESLKAFAERSLEEPFAYLILDARYEKVREAGVVMSQAVLIAVGIDWDGRRQILSVEMAGRESRSAWKDFLVRLKGRGLKGVELVVSDDHAGLVAAIGEVIPEAAWQRCYVHFLRNALDHLPRKHGDDCLQELRWLYDRRDLDEAKADLAAWLGKWSVRYPRLTSWVEETIEQTLTFF... | Required for the transposition of the insertion element. | Q52873 |
Q0AXL3 | DEF_SYNWW | Polypeptide deformylase | Syntrophomonas | MSVYQVITVPNDILRGKALPVKEINAGVLRVLDNMRDTMYAADGVGLAAPQIGIPKRMIVVDIGENLLELINPEILKQEGNQLGSEGCLSVPGIVGRVNRAKKVLVKGLDRNGQELNFAAVDLLAKVLQHEIDHLEGILFIDKAIETRIEKL | Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | Q0AXL3 |
Q6TH22 | DDI2_DANRE | Protein DDI1 homolog 2 | Danio | MLLTVFCAPRDRSETTFALDVSPELELRDFLALCELESGIPAGEIQIIYAEQPLQDPTRALGNYGLKDGDVLVLRQAERLRAPPQPTVPGLPRIDFSSIAVPGTSSGQNRNRPQQAQRPSTTQPPPPQATTSPGSGVSPQGLDNPALLRDMLLANPHELSLLKERNPPLAEALLSGDLERFTKVLMEQQQDRARRDQERIKLLTADPFDLDAQAKIEEEIRQHNIEENMTIAMEEAPESFGQVVMLYINCKVNGHPVKAFVDSGAQMTIMSQACAERCNIMRLVDRRWAGIAKGVGTQKIIGRVHLAQVQIEGDFLPCSF... | Aspartic protease that mediates the cleavage of NFE2L1/NRF1 at 'Leu-104', thereby promoting release of NFE2L1/NRF1 from the endoplasmic reticulum membrane. Ubiquitination of NFE2L1/NRF1 is a prerequisite for cleavage, suggesting that DDI2 specifically recognizes and binds ubiquitinated NFE2L1/NRF1. Seems to act as a pr... | Q6TH22 |
P00553 | KKA4_NIACI | Neomycin-kanamycin phosphotransferase type IV | Niallia | MNESTRNWPEELLELLGQTELTVNKIGYSGDHVYHVKEYRGTPAFLKIAPSVWWRTLRPEIEALAWLDGKLPVPKILYTAEHGGMDYLLMEALGGKDGSHETIQAKRKLFVKLYAEGLRSVHGLDIRECPLSNGLEKKLRDAKRIVDESLVDPADIKEEYDCTPEELYGLLLESKPVTEDLVFAHGDYCAPNLIIDGEKLSGFIDLGRAGVADRYQDISLAIRSLRHDYGDDRYKALFLELYGLDGLDEDKVRYYIRLDEFF | Resistance to butirosin and structurally-related aminoglycosides, including kanamycin and amikacin. | P00553 |
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