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2.75k
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5.51k
AlphaFoldDB
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B0K8Q5
MOAC_THEP3
Molybdenum cofactor biosynthesis protein C
Thermoanaerobacter
MNLTHINEEGRARMVDVSEKAETKREAVAIGSIYMKNETLRRIHEGTIKKGDVLAVAQVAGIMAAKNTSHMIPMCHPIMITGCDISFNLDFENSKIDIKAVVKTVGQTGVEMEALTAVTVAALTIYDMCKAIDRDMVISEIMLVKKSGGKSGLYEREV
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
B0K8Q5
Q71E95
CYB_ICHAL
Ubiquinol-cytochrome-c reductase complex cytochrome b subunit
Ichneumia
MTNIRKSHPLIKIVNESFIDLPAPSNISAWWNFGSLLGVCLILQILTGLFLAMHYTSDTATAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFMHVGRGVYYGSYTFMETWNIGILLLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIISALAAVHLLFLHETGSNNPSGISSDSDKIPFHPYYTIKDILGLLVMLMLLMTLVLFSPDLLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSIMVLAIVPLLHTSNQRGMMFRPLGQCLFWLLVADLLTLTWIGGQPVGHPFITIGQLASILYFSIILILMPIFGTIENQLLKW
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Q71E95
A1W2R0
RL2_ACISJ
50S ribosomal protein L2
unclassified Acidovorax
MAVIKIKPTSPGQRGAVKISRDHLYKGEAFAGLLEPQFQKAGRNNNGHITTRHKGGGHKHHYRVVDFRRNKDAIPAKVERIEYDPNRTAHIALVCYADGERRYIIAPRNLEVGATIVSGSEAPIRVGNTLPIRNIPVGSTIHCIELKPGAGAQIARSAGTSATLLAREGVYAQVRMRSGEVRKIHIECRATIGEVANEEHSLRQLGKAGVKRWMGIRPTVRGVAMNPIDHPHGGGEGRTGEGRHAVDPWGNLTKGYRTRNNKRTQVMIVSRRKK
One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
A1W2R0
B4T4I0
LPLA_SALNS
Lipoate--protein ligase
Salmonella
MTTLRLLISDSYDPWFNLAVEECIFRQMPATQRVLFLWRNADTVVIGRAQNPWKECNTRRMEEDNVRLARRSSGGGAVFHDLGNTCFTFMAGKPEYDKTISTHIVLAALNSLGVMADASGRNDLVVKTPDGDRKVSGSAYRETKDRGFHHGTLLLNADLSRLAIYLNPDKKKLAAKGITSVRSRVANLTELLPGITHKQVCQAVTEAFFVHYGERVDAEVISPDKTPDLPNFAETFARQSSWEWNFGQAPAFSHLLDERFTWGGVELHFDVEKGVITRAQVFTDSLNPAPLEALAERLQGCLYRADKLQETCEALLVDFPEQEKELRELSAWIAEAVR
Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.
B4T4I0
Q0HWD3
ZIPA_SHESR
Cell division protein ZipA
Shewanella
MEDLQLVLFVLGAIAIVAVLVHGFWSIRRQQPKSLKDSPMGNFYKKQAERGEGAPKRVDADGFDADGIGAVRVRKANEAHTPEAPAFNPYLKQEAKTQPQPVEPVQVEPKPLFEQEPSMAQPDFSLQSPTAKEQHRGPKASRQEPVLQGHSANLAQAHVGQSHAAMVAQKVAEEQRAQVQMPTQTALFDDEEPYEEEQSQAVEQADDDLGEPRDVLVLHVVAKEGQQLNGAELLPCFLTLNFKYGDMNIFHRHVDNAGNGKVLFSIANMVKPGIFDPDNMEQFSTQGVVFFMTLPCYGDALMNFSIMLNSARQLADDIDAVVLDGQRQPWGEFTKQDYLHRIRANA
Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
Q0HWD3
A1U380
LIPA_MARN8
Sulfur insertion protein LipA
Marinobacter
MSESAKPRITSGSKFRNEHGFSAIKDGVKRSSSNTEGKSLERKPKWLRARMPGGERYDAVRRNVTEHRLSTVCQESHCPNIGECWTNGTATIMVMGSVCTRACKFCAVDTGNPKGWLDPEEPENTAKSVELMGLRYIVLTSVDRDDLPDGGAAHYAACVSAIKQRTPEVAVEALTPDFDAVMSDVEKVVDSGLDVFAQNVETVKRLTSRVRDPRAGYEKTLSVLAHAKKHRPDVLTKTSLMLGLGETEEEILETMDDLRAIGVDILTLGQYLRPTPNHLPVERYVTPEEFNRYRDIGLEKGFMEVPSGPMVRSSYRADRVFDKNNLGLSVPEVPVPDKAMQIPVKAVD
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
A1U380
Q8TKU7
CYAS_METAC
Cysteate synthase
Methanosarcina
MGRFILKCLKCGREYSQEYRLTCENDDSFLRAEYLEKKLELRKQPGIGRFHSWLPVQEELTTEAGPITYKSEALARELGLSNLYIGFSGYWPEKGAFIKTCSFKELEAHPTMQLLKESGGKAIVLASAGNTGRAFAHVSALTGTDVYIVVPDSGIPKLWLPEEPTDSIHLISMTPGNDYTDAINLAGRIAKLPGMVPEGGARNVARREGMGTVMLDAAVTIGKMPDHYFQAVGSGTGGISAWEASLRLREDGRFGSKLPKLQLTQNLPFVPMYNAWQEGRRDIIPEIDMKDAKKRIEETYATVLTNRAPPYSVTGGLYDALVDTDGIMYAVSKEEALDAKALFESLEGIDILPPSAVAAASLLKAVEAGNVGKDDTILLNIAGGGFKRLKEDFTLFQIEPEITVSNPDVPLEELKL
Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate. Does not display threonine synthase activity like the paralog protein ThrC.
Q8TKU7
Q34376
CYB_DASRO
Ubiquinol-cytochrome-c reductase complex cytochrome b subunit
Dasykaluta
MISLRKSHPLLKIINHAFIDLPAPSNISAWWNFGSLLGICLIIQILTGLFLAMHYTSDTLTAFSSVAHICRDVNYGWLLRNLHANGASMFFMCLFLHVGRGIYYGSYLYKETWNIGVILLLTVMATAFVGYVLPWGQMSFWGATVIMNLLSAIPYIGTTLAEWIWGGFAVDKATLTRFFAFHFILPFIIVAFAAVHLLFLHETGSNNPTGINPDSDKIPFHPYYTIKDALGLIFLILSLLLLGLFSPDLLGDPDNFSPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLASILILLIIPLLHTANQRSMMFRPIFQTLFWILTADLITLTWIGGQPVEQPFIIIGQLALMLYFLLILALMPLAGMFENYMLEPKW
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Q34376
A0B5R2
CETZ_METTP
Cell-structure-related euryarchaeota tubulin/FtsZ homolog
Methanothrix
MLNVLMLGVGQCGNRILDAVNRQAFGGSRLAKYYSKQRFPSRVETIAINTAINDLKELKFTAAKDRLHVPNLHGVGANRSKGKQGFWENQEMILEEIEKRGDFDLIFVMTSVSGGTGSSFSPLMIHELKKRYKNATIVPIAVLPFREEGTIYLQNAAFCLREMIEVEADGMILVDNQYLKRFSGDIASAYDRINTMVAQRLLFLIEALDSEMLSVTDLGDFKTVMNGGLRMGTLGYYQADKKSPSIRAAIKNSLREVGLLYPANVDAGEAGRAMIVIQGSREYLNVDEITKEIESLTETIGHVFKGIVIKKGEPRVLSVLSLERAPGLVELYEKAKWAIQEERERKDRARSELYEAFEQINDLEEIY
Involved in cell shape control.
A0B5R2
Q8H1Q7
GMPP3_ARATH
Probable mannose-1-phosphate guanylyltransferase 3
Arabidopsis
MPKPLVDFGNKPMILHQIEALKGAGVTEVVLAINHQQPEVMLNFVKEYEKKLEIKITFSQETEPLGTAGPLALARDKLVDESGQPFFVLNSDVICEYPLLEMIEFHKTNRAEASIMVTEVDDPSKYGVVVTEEGTARVESFVEKPKHFVGNKINAGIYLLSPSVLDRIELRRTSIEKEIFPKIASEKKLYAMVLPGFWMDIGQPKDYITGQRMYLNSLREKTPQELATGDNIIGNVLVHESAVIGEGCLIGPDVVIGPGCVIDSGVRLFGCTVMRGVWIKEHACISNSIVGWDSTVGRWARVFNITVLGKDVNVADAEVYNSGVVIEEQGL
Catalyzes a reaction of the Smirnoff-Wheeler pathway, the major route to ascorbate biosynthesis in plants.
Q8H1Q7
P0C523
CYB_ORYSI
Ubiquinol-cytochrome-c reductase complex cytochrome b subunit
Oryza sativa
MTIRNQRFSLLKQPIYSTLNQHLIDYPLPSILSYWWGFGSLAGICLVIQIVTGVFLAMNYTPHVDLAFNSVEHIMRDVEGGWLLRYMHANGASMFFIVVYLHIFRGLYYASYSSPREFVWCLGVVIFLLMIVTAFIGYVLPWGQMSFWGATVITSLASAIPVVGDTIVTWLWGGFSVDNATLNRFFSLHYLLPFILVGASLLHLAALHQYGSNNPLGVHSEMDKIAFYPYFYVKDLVGWVAFAIFFSIWIFFAPNVLGHPDNYIPANPMSTPPHIVPEWYFLPIYAILRSIPDKAGGVAAIALVFISLLALPFFKEMYVRSSSFRPIYQGIFWLLLADCLLLGWIGCQPVEAPFVTIGQISSFFFFLFFAITPILGRVGRGIPKYYTDETHRTGSFS
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
P0C523
H2L006
TSP14_CAEEL
Tetraspanin-14
Caenorhabditis
MPHRAPRRFMKTAPGACDWEQCLLMGSGEPTRARAVVSSSHKQRKPRQEISACLKWLVFLLNSIVFLVGVGILALGVYLFIKDFREVKLVDIILNPAILISIFGFSICVVSFFGFMGALRDNIFLLKCFAACVFLSYILVVAVTLVFFTLFYTDTTEGLSANWLLLYAVKNYHTNRNLAEIMDALQENLECCGVSSIAQGYRDWNMSYQFNCTNSNPQPEKCGVPFSCCRKSVISEAAGSSNPLLPAMRSLECWQNALTKRPGDLEHDIYTRGCLQPLRTLFESHAVHVGAFVALLIVPVCISVCLTNILAKQVDHQRYLLEREARRNDRRRKRDHNRRDQLNSLDLLEEGKFNNASANATRPRPPDIPPPLPPIEHVPRKKSRNASSSPTRKPKSAGVENAAARRKRTATTTRTPPAAAGPAPTPQATTTNRTHQWVLQQTDLVPQKSKS
Together with tsp-12, regulates cell fate specification in the postembryonic mesodermal M lineage, body size and male development, probably by positively modulating BMP-like Sma/Mab signaling . Together with tsp-12, probably acts by modulating the activation of glp-1, Notch-like receptor, to regulate germline maturation .
H2L006
A4XZ78
RL5_PSEMY
50S ribosomal protein L5
Pseudomonas
MARLKEIYRKEIAPKLKEELKLANVMEVPRITKITLNMGLGEAIGDKKVIENAVADLEKITGQKVVVTHARKSIAGFKVREGWPIGVKVTLRRERMYEFLDRLLSISLPRVRDFRGLNAKSFDGRGNYSMGVKEQIIFPEIDYDKIDALRGLDITLTTTARNDDEGRALLRAFNFPFRN
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
A4XZ78
Q5BJZ6
CARME_RAT
Anserine-producing methyltransferase
Rattus
MQRRRRAPPASQPAQDSGHSEEVEVQFSAGRLGSAAPAGPPVRGTAEDEERLEREHFWKVINAFRYYGTSMHERVNRTERQFRSLPDNQQKLLPQFPLHLDKIRKCVDHNQEILLTIVNDCIHMFENKEYGEDANGKIMPASTFDMDKLKSTLKQFVRDWSGTGKAERDACYKPIIKEIIKNFPKERWDPSKVNILVPGAGLGRLAWEIAMLGYACQGNEWSFFMLFSSNFVLNRCSEVDKYKLYPWIHQFSNNRRSADQIRPIFFPDVDPHSLPPGSNFSMTAGDFQEIYSECNTWDCIATCFFIDTAHNVIDYIDTIWRILKPGGIWINLGPLLYHFENLANELSIELSYEDIKNVVLQYGFQLEVEKESVLSTYTVNDLSMMKYYYECVLFVVRKPQ
N-methyltransferase that catalyzes the formation of anserine (beta-alanyl-N(Pi)-methyl-L-histidine) from carnosine. Anserine, a methylated derivative of carnosine (beta-alanyl-L-histidine), is an abundant constituent of vertebrate skeletal muscles. Also methylates other L-histidine-containing di- and tripeptides such as Gly-Gly-His, Gly-His and homocarnosine (GABA-His).
Q5BJZ6
Q55GG6
ERCC1_DICDI
DNA excision repair protein ERCC-1
Dictyostelium
MSSQQTDNNPIPTTTTNNNTNNDNDIASTNNNTNNDDDSTTTNTSTNKPRKRFVIPSASQALKKSDLSMVEINSKLKQAEENAKQAEDLQKSNAIILTPKSTTTMTTTTTPVQQRMPIPSILAKRNVNTTTTTSTSPLSTSPPISSPLQTPYYSPSFVKNPTSPAPINKPIGPSLPMRPSLPKKPAAYSTTLSTYSSSSSSYSSSTTTQNYQHIDKIYANSKQRGSLMMNSFSKNIIIEYSELQYPDFILNSNTLVFYLPSLKTHRDNPNLIQDRIKGLSTLMTNSDSFTLRILLVFADLSDSDNCEQFINELNLIAIKLQFTLIVCWSQIEAAKYLEAYKTFNNRAPDPIKARAQPIELGGKSKNEQVLTSIKSVNKTDATTLLKNFQTMQQIFTCQKTTLSKLPGFGPVKVQKFYNTINQPFKTKPSTKTTTTTTTTTTTTTSANISSNNNNNNINTNDGNNNNNTINNINFNNDENEVDQDPLNFSFDFGGNGNGDGDSDGDGESENQINT
Structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair.
Q55GG6
P95519
IHFB_MANHA
Integration host factor subunit beta
Mannheimia
MTKSELIESLASKNPSLPIKMVEHCVKELLEQLTATLEEGERIEVRGFGSFSLHYRQPRLGRNPKTGESVLLGAKYVPHFKAGKDLKERVDLL
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
P95519
Q24009
BICC_DROME
Protein bicaudal C
Sophophora
MLSCASFNKLMYPSAADVAKPPMVGLEVEAGSIGSLSSLHALPSTTSVGSGAPSETQSEISSVDSDWSDIRAIAMKLGVQNPDDLHTERFKVDRQKLEQLIKAESSIEGMNGAEYFFHDIMNTTDTYVSWPCRLKIGAKSKKDPHVRIVGKVDQVQRAKERILSSLDSRGTRVIMKMDVSYTDHSYIIGRGGNNIKRIMDDTHTHIHFPDSNRSNPTEKSNQVSLCGSLEGVERARALVRLSTPLLISFEMPVMGPNKPQPDHETPYIKMIETKFNVQVIFSTRPKLHTSLVLVKGSEKESAQVRDATQLLINFACESIASQILVNVQMEISPQHHEIVKGKNNVNLLSIMERTQTKIIFPDLSDMNVKPLKKSQVTISGRIDDVYLARQQLLGNLPVALIFDFPDNHNDASEIMSLNTKYGVYITLRQKQRQSTLAIVVKGVEKFIDKIYEARQEILRLATPFVKPEIPDYYFMPKDKDLNLAYRTQLTALLAGYVDSPKTPSLLPPSLAGQLTPYANNNHLLLNANGLATPTGVCAPTQKYMQLHNSFQQAQNRSMVAGGQSNNGNYLQVPGAVAPPLKPPTVSPRNSCSQNTSGYQSFSSSTTSLEQSYPPYAQLPGTVSSTSSSTAGSQNRAHYSPDSTYGSEGGGVGGGGGGGARLGRRLSDGVLLGLSNSNGGGGNSGGAHLLPGSAESYRSLHYDLGGNKHSGHRAFDFDMKRALGYKAMERTPVAGELRTPTTAWMGMGLSSTSPAPAPLENGENGAAGGGASSGWRLPPGLGSPYGLSATTGLLDATPVNRRMQLAKHKDIQTLLTSLGLEHYIKIFVLNEIDLEVFTTLTEENLMELGIAAFGARKKLLTAIHTLLANEAACSTMPSSSSSQNSSSPRFSGSAAPGAERRPSNQW
RNA-binding protein that is involved in oogenesis. Required for correct targeting of the migrating anterior follicle cells and the establishment of anterior-posterior polarity in the oocyte. May act as translational repressor of oskar during oogenesis. Function seems to be sensitive to small changes in expression.
Q24009
Q07YC7
GCST_SHEFN
Glycine cleavage system T protein
Shewanella
MASKTVLFNKHLESKAKMVDFHGWEMPINYGSQIEEHHAVRQDAGMFDVSHMTVVDVTGSDACAFLRKLLANDVAKLTVPGKALYGGMLDENAGIIDDLITYYLTDTHYRVVVNSATRDKDLAWINKQAAAFDVVVTERPELAMIAVQGPNAKAKAATVFSAEQNAAVEGMKPFFGVQSASLFIATTGYTGEAGYEIIVPETEAEALWQALLDAGVKPCGLGARDTLRLEAGMNLYGQDMDESINPLAANMGWTVAWEPSERDFIGRDALTAIKAAGTDKLVGLVMEEKGVLRHDMAVFFTDADGVEHQGVITSGSFSPTLGYSIAMARVPSGIGAIAEVEMRKKRVNVKVIAPSFVRNGKQAF
The glycine cleavage system catalyzes the degradation of glycine.
Q07YC7
Q9UY53
PCKG_PYRAB
Phosphoenolpyruvate carboxykinase [GTP]
Pyrococcus
MEKLKRFLPEDQYEKLAAINNPYLHEFLAEWIEWLKPSKVFVCTDSPEDEEYVRWKALYYGEEKMLEMPRHTVHYDNYYDQARDKANTKLLVPKGVTLPFLNTMDREEGLKEIREIMKGIMKGKELFICFFVLGPRNSIFTIPAVQLTDSAYVAHSEFLLYRKGYEEFKRLGPTKNFLKFVHSAGELDERKTSKNLDKRRIYIDLVDETVYSANTQYGGNTIGLKKLAFRLTIQRAVREGWLSEHMFLMRVNGPNGRKTYFTGAYPSMCGKTSTAMIPWENIVGDDLVFIKNVDGTARAVNVEIGVFGIIEGINEKDDPIIWQVLHSPVEIIFSNVLVKDGKPYWNGMGIEIPDEGENHSGKWWRGKRDKEGNEIPPSHKNARFTVRLEAFPNLDKEALENPCGVEVGGMIFGGRDPDTWPPVREAFDWEHGVITMGASLESETTAATLGKEGVRAFNPMSILDFLSVHLGDYIRNYLEFGRKLKKKPKIFAVNYFLRENGKWLNEKLDKAVWLKWMELRVHGDVEAIETPIGYIPKYEDLRELFKQVLNKEYKKEDYEKQFKIRVPELLAKIDRIWNIYEPIGNIPEELFKQLEEERERLLKAREKYGDYISPFSLL
Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
Q9UY53
Q6D1S8
RECA_PECAS
Recombinase A
Pectobacterium
MAIDENKQKALAAALGQIEKQFGKGSIMRLGEDRSMDVETISTGSLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLQVIAAAQREGKTCAFIDAEHALDPIYAKKLGVDIDNLLCSQPDTGEQALEICDALTRSGAVDVIIVDSVAALTPKAEIEGEIGDSHMGLAARMMSQAMRKLAGNLKQANTLLIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRTGAIKEGEEVVGSETRVKVVKNKVAAPFKQAEFQILYGEGINIHGELVDLGVKHKLIEKAGAWYSYNGDKIGQGKANACNFLKENPTISAELDKKLREMLLHKGNELKPAAAGNSHDEDELAGEGKEEF
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
Q6D1S8
C6EHJ8
RUTD_ECOBD
Aminohydrolase
Escherichia
MKLSLSPPPYADAPVVVLISGLGGSGSYWLPQLAVLEQEYQVVCYDQRGTGNNPDTLAEDYSIAQMAAELHQALVAAGIEHYAVVGHALGALVGMQLALDYPASVTVLISVNGWLRINAHTRRCFQVRERLLYSGGAQAWVEAQPLFLYPADWMAARAPRLEAEDALALAHFQGKNNLLRRLNALKRADFSHHADRIRCPVQIICASDDLLVPTACSSELHAALPDSQKMVMPYGGHACNVTDPETFNALLLNGLASLLHHREAAL
Involved in pyrimidine catabolism. May facilitate the hydrolysis of carbamate, a reaction that can also occur spontaneously.
C6EHJ8
Q5MJP4
SCX2_ANUPH
Phaiodotoxin-2
Anuroctonus
KFIRHKDESFYECGQLIGYQQYCVNACQAHGSKEKGYCKGMAPFGLPGGCYCPKLPSNRVKMCFGALESKCA
Sodium channel (Nav) specific neurotoxin.
Q5MJP4
Q6YRK2
RL9_ONYPE
50S ribosomal protein L9
Candidatus Phytoplasma asteris
MFSKNKHNTKFIVIACVIVVLILILFCLDFQNIQEIIETINQLTNNQNPSQNTASEMSGMRRKIIFFIFNFFGKIILASFVISFLLHIKKNAQIKRLKNKLSLWSKLSFHVSQIGEEVLNELPIGIVLIDISSQEIQWLNPYASFILKNPEINSPLAQINENMAQLISTSDAIPKTIITLENKKFECFYKKDLNVFYLFDATEKEQIKHLFLQKTLALAMITFDNLAESLIRYDLSEQSQIQGEYLSALSDYIEPYEGYLKQLIDDRFLLLLNRQNLDKMLENKFIILDTIRNISYKYQLKVTLSMGIACWNLSYEKLATYSQNAIELAQKRGGDQVVVNIENEKIKYFGAKIASLSKQSKVHARINAQNLVDILKKHPHCFIMGHTHTDLDALGSVIAFYKIATTIHPESNNYIILDEEKLDKSLIPVYNQLIKTEAKTSLNIITTQQASKMIKDNSLIAVLDTQTKDMVNSPELLSLTSNVVVVDHHRATEEIIPSIFSYVESSASSTVELLVEVMGFLEKEVHITAFEASIMYAGILIDTNAFIYRTSSRTFEVASKLKDLGADAIEVKSWLRKDFDKVLEINKLISEMEIFMDRFAIIQSSEIYENRSFLAQVAEGVLNIRNVDAAFMIAQIADNKIAISARSYNEINVQTIMEQMEGGGHLNSAATQLEGTNIKTVTDTLKHFLKLEYEKGEKNMEIILLTDIPNKGKKHEIIKVNNGYGNFLIQNKKALLADKTNLAAIKQSQMLEQEQKRNHELLMHKLKQEIDDKKITLDIQLGPKGKIYGKITLKQIAEEFLKVHNITLDRKKISLEGEIIAIGIYPVDVFLTDQIKATFFLNVTERKSK
Binds to the 23S rRNA.
Q6YRK2
Q6D4U2
TRPD_PECAS
Anthranilate phosphoribosyltransferase
Pectobacterium
MQLSSTQPSSKTQEPSTAQDVITMQHILEKLYGANSISRQESQALFGAIIRGELEASQLAAALISMKVRGEHPDEIAGAATALLADAQPFPRPDYLFADIVGTGGDGTNSINISTASAFVAASCGLKIAKHGNRSVSSRSGSSDLLSAFGIKLDMSAQDSRQALDDLGVCFLFAPQYHLGFRHAMPVRQQLKTRTVFNVLGPLVNPARPPLALIGVYSPELVRPIAETLKVLGYQRAAVVHGGGMDEVAIHAPTQVAELNHGEIETYELTHRDFGLDTHPLSALQGGTPEENRDILASLLQGKGERAHAAAVAANVALLLRLFGQEDLRQNAQQALEVIHSGQAYQRVIALSARG
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
Q6D4U2
C3TS06
STX74_ANEVI
Neurotoxin 7
Anemonia
MMNRLLVFLMLGAFMLVVSANDAYGDEPAFKDLNQGDESLGKRKSCCPCWLRGNCFWGQNCYPEGCSGPKV
Voltage-gated sodium channel (Nav) inhibitor. 1 uM completely inhibits insect voltage-gated sodium channel inactivation (DmNav1 from D.melanogaster).
C3TS06
P20487
FLIJ_BACSU
Chemotaxis CheF protein
Bacillus
MAYQFRFQKLLELKENEKDQSLSEYQQSVSEFENVAEKLYENMSKKELLEQNKEKKLKSGMSVQEMRHYQQFVSNLDNTIYHYQKLVIMKRNQMNQKQEILTEKNIEVKKFEKMREKQFKMFALEDKAAEMKEMDDISIKQFMIQGH
Flagellar protein that affects chemotactic events.
P20487
Q332S2
NU1C_LACSA
NADH-plastoquinone oxidoreductase subunit 1
Lactuca
MIIDTTEVQAINSFSILESLKEVYGIIWMLIPIFTLVLGITIGVLVIVWLEREISAGIQQRIGPEYAGPLGILQALADGTKLLFKENLLPSRGDTRLFSIGPSIAVISILLSYLVIPFSYHLVLADLSIGVFLWIAISSIAPVGLLMSGYGSNNKYSFLGGLRAAAQSISYEIPLTLCVLSISLLSNSSSTVDIVEAQSKYGFWGWNLWRQPIGFLVFLISSLAECERLPFDLPEAEEELVAGYQTEYSGIKFGLFYVASYLNLLVSSLFVTVLYLGGWNLSIPYIFVPEVFEITKRGRVFGTIIGIFITLAKTYLFLFIPIATRWTLPRLRMDQLLNLGWKFLLPISLGNLLLTTCSQLISL
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
Q332S2
A0L4Y9
RL19_MAGMM
50S ribosomal protein L19
Magnetococcus
MNQVQAFEQSMIPETAVPKFGAGDTLKVHVKVVEGTRERIQVFEGVCIGRMNAGLRSTFTVRKISFGEGVERTFPVYSPRVDKIEVIRHGDVRRAKLYYLRGRTGKASRIKEKRDW
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
A0L4Y9
Q9MUU5
RK5_MESVI
50S ribosomal protein L5, chloroplastic
Mesostigma
MVQRLKTLYLESAVLKLQETFGYKNPHQIPRIKKIVINCGLSEASQNSKSLESAMKELSIIAGQKGVITRAKKAIAGFKIREGLPIGICITLRGDSMYAFLDRLINLALPRIRDFQGVSSKSFDGHGNYNLGLKEQLMFPEIDYDQIDKIRGMDICIVTNAKTDSEGFYLLEVLGMPFKEKFAN
Binds 5S rRNA, forms part of the central protuberance of the 50S subunit.
Q9MUU5
A0A193PS46
STBB_STABI
Nonribosomal peptide synthase-like protein stbB
Stachybotrys
MGSLGSSQLKPFNKAPIDFVSTKRQPGAVCSLPELVDYNAQHNASHNFCIQGKPGGEFDTFTHADFKVAAANCAKWLKANLPLGASQAPNAITKNAPVALFMESDFGLVVHEFALLSLGIPPLVLSVRLPPNAIMHLLKSTGATSFIVSQKLSGPAKPALAALAANGIATAVGNPYTSFLEPGVDVASKGTFEVPENPDDITLLLHSSGTTGLPKPIPISHRMLMFAVSTAKFDTEDEAQGLNVSSLPLFHGFGLVAPGISMTVGKTTVYPASDGIPNIVSIIDLIKRTNARSLMTVPFLLDDVINNEEGLRVLAGLDFVGTGGAALGPGVGDKLAAAGIKLLNFYGTTESGPLSLVFVPKDNYNWKFFRLRTDMNFEIANLEPKDGVKRYRLTIRAFGEGEDQEIADQLIRNDEYPETDFAAVGRDDDVIVLATGEKASPQILENMLTEAPMVKAAIAFGENQFNLGVIVEPKEPLAEGGEAAFKELIWPIIVAAGQKMDAHSVIPSQEAVIVVPNGVRVPRTDKGSIARKEVYALFADAMKDVYEKLARAVGGADLKPLDLETLEEDIKALIIEHSGLKVPAEGLSAEESLFDFGLDSLQALKLRRVLAAAANKSEAMKDVNVDKVIPPEFVYLNPSVAQMAAAIKNPSAGSAAPTVDANAYKGVEKFAEQYALPGASAEEKAPSVRERAIVVVTGSSGSLGSHVVATLARDPKVMRVVVMVRQGSKPFDREPWTSRGINLKEDEFAKIVPLPVDPTAENLGVDPMMYGMLQNNLTHIVHAAWPMNYLTTLPSFQYQFEYLSGLLKLATSGNTANKRRFIFVSSIAAVARLSLSNSGAMISETPVEPVDAACGIGYADGKLVCEKILEKAAVSHAGQLEIAYVRCGQMTGSRATGAWNADEQIPMIFRTAKNLGVLPRIPGTLSWIPVDDAAQYIMDLSFFEGALPIASHLENPVRQSWADLMDGAGKFLGIQKSVSWPEWLELAGAAEDGPQDKYPVKKLFAFFKFSFGPMASGAVILGTDVARAHSATIKNMGALDASTIMKYFLHWQKINYL
Nonribosomal peptide synthase-like protein; part of the cluster that mediates the biosynthesis of LL-Z1272-beta, also known as ilicicolin B, a prenylated aryl-aldehyde produced by several fungi and that serves as a key pathway intermediate for many fungal meroterpenoids . The first step in the pathway is performed by the non-reducing polyketide synthase stbA that produces orsellinic acid by condensing acetyl-CoA with 3 malonyl-CoA units . The prenyltransferase stbC then prenylates orsenilic acid into grifolic acid . Finally, grifolic acid is reduced to ilicicolin B by the NRPS-like protein stbB .
A0A193PS46
Q6HLF2
LEU3_BACHK
Beta-IPM dehydrogenase
Bacillus cereus group
MEKRIVCLAGDGVGPEVMESAKGVLHMVERLYGHHFHLQDEHFGGVAIDLTGQPLPQRTLAACLASDAVLLGAVGGPRWDGAKERPEKGLLALRKGLGVFANVRPVTVESATAHLSPLKKADEIDFVVVRELTGGIYFSYPKKRTDEVATDTLTYHRHEIERIVSYAFQLASKRKKKVTSIDKANVLESSKLWRTVTEEVALRYPDVELEHILVDAAAMELIRNPGRFDVIVTENLFGDILSDEASVLAGSLGMLPSASHAEKGPSLYEPIHGSAPDIAGKNKANPIAMMRSVAMMLGQSFGLTREGCAIEEAISAVLKSGKCTADIGGAETTTSFTKAVMQEMEEQALVGRGR
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
Q6HLF2
A9KLM3
RIMM_LACP7
Ribosome maturation factor RimM
Lachnospiraceae
MEDLLRVGVISSTHGIKGEVKVFPTTDDMNRFKKLKMVTLDTGKEQKELEIENVKFFKQFVILKFKGIDNINDIEKYKGKDLLISRENAVDLAEGEFFIFDLIGLQAEEEDGNSLGELTEVLQTGANDVFVIKTKQGKEILIPYIDDCVKKIDLNEKKLVVHLIPGLVE
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
A9KLM3
Q2YIU9
ALR_BRUA2
Alanine racemase
Brucella
MSLPFSQDERDLAAGGILTIDLAALRHNYSAIATRIAPTRTAAVVKADAYGLGASRVAPAFYEAGCRDFFVAHLGEAVALKPFLKPDATLYVLNGLQPGTEAACAREGILPVLNSLEQVENWAALATRLGKKLPALLQFDTGMSRLGLSAKEFDRLLENVTLLSRIDIKFAISHLANGDEPGNAVNARQLAKMTALLARLPKLPAALANSGGTFLGKTYYFDLARPGIALYGIDPERQHDFSDKVAHENKKPKHSILPVLTLSARVIQVRDVDKGATVGYGGTYVANGPMRIATIAVGYADGLFRSLSNKGAAFFGDTRLPIIGRVSMDSITLDVTSLPEGTLKLGSLVELIGPHQRLEDVARDCDTIPYEILTALGNRYARVYVYVNGGGTSTTA
Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.
Q2YIU9
B4PIW8
UBP36_DROYA
Ubiquitin-specific-processing protease 36
Sophophora
MPVSMAVCETANVVNAALRESLGGNSSAAGSSIDQAKSGEDSNGSLQNHIVANAKRILMAKIEYEEVPNYHESVLENLKSKYIVIKPGNPGAINGFGGKNNTGKVVGANGHDNNGARKQAEHPNNQSHHNNHNNHPHPTSNPNELPKPKRVLYPRENIRIGWKQSERKWQVGTGMINVGNTCYLNSTLQALLHIPALANWLVSEQAHLENCNVAESGGGCIVCAMAKTLLATQSNQSAVRPFLIYSKLKQICKHMVVGRQEDAHEFLRFLVEAMERAYLMRFRNYKELDQLVKETTPLGQIFGGYLRSEVRCLSCNHVSITFQHFQDLLLDIRKADSLEDAFEGHFSRERLEDMGYKCEGCKKKVSATKQFSLERAPITLCIQLKRFSMIGNKLTKQISLKPRIDLSKYAARSPAAQAQPLTYRLVSMVTHLGVSQHCGHYTAIGSTDTGSYYNFDDSYVRPIAMQSVCNTNAYIMFYELDLSQAASPAANRPNGVRLTNGHSTTPVPAATVSSPSPTRFIGPQLPPGGVNGYSNGNAQKTAIQFKQHHQQSQQNGFQLGTGKFQDTAKPPLVGAHAKGDANPVPTANGNKSSSTSSNSSSNHKSINQQQYLPISSEDEDSEDEMTPRPTTAQLPSMPKMTDDHTEKPKSPVKIQVKTPVKTPLKSLVPYESASEEEEAPQPNPRKRRSEEDSSESDQESGQTNGHSKTNGSLTNGSASSSVHVNNSKQKTDAIDEIFKSLKKSADSDDDDDEEESSIQLTNGWHPQKQSQSQSKAPPSPKTPPSPAVIKSKTGIWKVTRNDEVDDIDDDDDEEDEAPAKIQTPSKTHRNPFSSTKPSTESPATPGAKRQKLLNGSAVKSHQQPRVGNGYQSEATSNGSTINELLKQSHRGYGSSVLSWNGKPAELEKEPFELVCAKRIAGHGSVDGSDIVESSVAVNASSGSDSNDVVVIALLVDAREQRQRDLDDDEENEMDRGRQRKVKSSGSAKANNASNSTPGYNPFQEYEGQKRWNKNGGGGGGFPRFYNQNFRQNFQQRNKFKFNRFGGPGSAKFQQQRALQRHLAAGGGFSRRQPSAQQQQQQS
Required for maintaining multiple types of adult stem cells, including male and female germline, epithelial follicle cell and intestinal stem cells. May function as a transcriptional repressor by continually deubiquiting histone H2B at the promoters of genes critical for cellular differentiation, thereby preventing histone H3 'Lys-4' trimethylation (H3K4). Controls selective autophagy activation by ubiquitinated proteins.
B4PIW8
A3N1E6
RECX_ACTP2
Regulatory protein RecX
Actinobacillus
MTNYTAINYLLYLLSKRDYSEQDLRRKLVQKEYSQEEIEQAIERAQANNWQSDERYCAGFIRYRSQQGIGPRRLKQELKLKGIKDWLINQELENAEIDWFILAEQVFEKKRPQVWDIKAKQKMWRFMLSRGFYNDHFSHLMDIDYNDTEYE
Modulates RecA activity.
A3N1E6
Q91554
ARGN2_XENLA
Arginase, non-hepatic 2
Xenopus
MSIRSNFVRLLKKQVSIIKLQKKCSHSVAVIGAPFSKGQKRRGVEHGPAAIRSAGLIERLSNLGCNVCDFGDLHFSKVPNDELYNSIVKHPRTVGLACKVLAEEVSKAVGAGHTCVTLGGDHSLAFGSITGHAQQCPDLCVIWVDAHADINTPLTTPSGNLHGQPVSFLLRELQDKVPPIPGFSWAKPCLSKSDIVYIGLRDLDPAEQFILKNYNISYYSMRHIDCMGIKKVMEKTFDQLLGRRDRPIHLSFDIDAFDPALAPATGTPVIGGLTYREGVYITEEIHNTGMLSAVDLVEVNPVLAATSEEVKATANLAVDVIASCFGQTREGAHTRADTIIDVLPTPSTSYESDNEEQVRI
As well as its role in the urea cycle, may be involved in tissue remodeling.
Q91554
C0HK45
LTX2A_ECTBR
Ponericin-Q42
Ectatomma
FWGAVWKILSKVLPHIPGTVKWLQEKV
Antimicrobial peptide forming an alpha-helix in watery and membraneous environments, enabling it to perforate membranes. Active against Gram-negative bacteria E.coli DH5alpha (MIC=5 uM), E.coli MH1 (MIC=0.6 uM) and P.aeruginosa PAO1 (MIC=10 uM) and against Gram-positive bacteria B.subtilis VKM B-501 (MIC=0.6 uM) and A.globiformis VKM Ac-1112 (MIC=0.2 uM). Has cytolytic and hemolytic activity.
C0HK45
Q16AH6
PCKA_ROSDO
Phosphoenolpyruvate carboxykinase (ATP)
Roseobacter
MTHGRVNPDFRLEDQGITGLGTVYYNLIEPDLIQYALARGEGSLGKGGSFLVTTGKFTGRSPKDKHVVKTDSVADTIWWENNREMSPEGFDQLYTDMLAHMEGRDYFVEDLTGGSDPKHAINVRMVTELAWHGLFIRHMLRRPDREDLDDFIADFTVINCPSFQADPAKHNCRSETVIAMNFDKKLILIGGTEYAGENKKSVFTLLNYLLPEKGVMPMHCSANHAVGNPVDTAVFFGLSGTGKTTLSADPARTLIGDDEHGWSDTGTFNFEGGCYAKTISLNPEAEPEIYATTEKFGTVIENMVYDAETKDLDFEDDSLTANMRCAYPLHYISNASQAARGGHPKNIIMLTCDAFGVLPPISRLTPAQAMYHFLSGFTSKVAGTERGVTEPEPTFSTCFGAPFMPRRPEVYGNLLREKIATHGATCWLVNTGWTGGAYGTGSRMPIKATRGLLTAALDGSLADAEFRKDPNFGFQVPVDVTGVPGILLDPRRTWDDAEAYDRQAAKLVKMFSDNFEQYLPFIDEDVRAAAIS
Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
Q16AH6
Q05638
CHIX_STROI
Exochitinase 1
Streptomyces
MDRFRPLAVLIAAALTLSGTTALSSAARAADADLARNGGFEAGLDGWTCTAGTTVNSPVRSGSSALKATPAGSDNARCAQTVTVQPNSQYTLSGHVQGSYVYLGASGTGTTDVSTWTQSAPDWRQLTTTFRTGPSTTRVTLYTHGWYGTGAYHADDISLVGPGGGTEQPPAPPTGLRTGSVTATSVALSWSPVTGATGYAVYRDGVKVATASGTSATVTGLTPDTAYAFQVAAVNGAGESAKSATVTATTAPGTGGGSADLPPHALVGYLHASFANGSGYTRLADVPDSWDVIDLAFGEPTSVTSGDIRFDRCPATECPNVESDAEFKAAIKAKQAAGKKVLISIGGQNGQVQLTTTAARDTFVSSVSKIIDEYGLDGLDIDFEGHSLSLNADDTDFKNPKTPVIVNLIQALKTLKAKYGDDFVLTMAPETFFVQLGYQYYGTGKWGGQDPRAGAYLPVIHALRDDLTLLHVQDYNSGPIMGLDNQYHSMGGADFHIAMTDMLLTGFPVAGDAANVFPPLRADQVAIGMPATTNAGNGHVAPAEAVKTLDCLTRKTNCGSYATHGTWPALRALMTWSINWDRFGGWEFQRTFDGYFG
Exochitinase that generates exclusively chitobiose from chitotetraose, chitohexaose, and colloidal high-molecular mass chitin.
Q05638
Q0TUE3
ACPS_CLOP1
4'-phosphopantetheinyl transferase AcpS
Clostridium
MIIGIGVDIIEIERVRQAIQNNKNFLSKLFTEREIDYFISRNMNSEVIAGNFAAKEAVSKALGTGIRGFSFKDIEILRNELGKPEVILHNGANLIGNKLVENNNSLRVHLSISHNNSSAIAYSVLEGEYYGNM
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
Q0TUE3
Q3II82
RL9_PSET1
50S ribosomal protein L9
Pseudoalteromonas
MQVILLDKIANLGGLGDQVVVKSGFARNFLFPQGKAVPATKANIETFDARRAELEAKIADQLVAAQARADKLEALAEVTLVSKAGDEGKLFGSIGTRDIADAISAVGVEVAKSEVRLPLGTIRETGEFDVSIAVHSEVTATIKVIVIAEA
Binds to the 23S rRNA.
Q3II82
Q28133
ALL2_BOVIN
Dermal allergen BDA20
Bos
MKAVFLTLLFGLVCTAQETPAEIDPSKIPGEWRIIYAAADNKDKIVEGGPLRNYYRRIECINDCESLSITFYLKDQGTCLLLTEVAKRQEGYVYVLEFYGTNTLEVIHVSENMLVTYVENYDGERITKMTEGLAKGTSFTPEELEKYQQLNSERGVPNENIENLIKTDNCPP
Probable pheromone carrier.
Q28133
Q7XJ39
NLT2A_ORYSJ
Non-specific lipid-transfer protein 2A
Oryza sativa
MARAQLVLVALVAAALLLAGPHTTMAAISCGQVNSAVSPCLSYARGGSGPSAACCSGVRSLNSAASTTADRRTACNCLKNVAGSISGLNAGNAASIPSKCGVSIPYTISPSIDCSSVN
Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.
Q7XJ39
A6R989
URM1_AJECN
Ubiquitin-related modifier 1
unclassified Histoplasma
MGSIASPSLSSSSQLLTITVEFTGGLESIFNNTRKHTLSIPATYPSPSTGEPEPTSVASLVHYLIENVMEDTRQELFVVDGAVRPGILVLINDADWELEGEEKYQIQQGDNILFVSTLHGG
Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as AHP1. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
A6R989
Q2GHF4
RS6_EHRCR
30S ribosomal protein S6
Ehrlichia
MPLYEFTFIAQQGLTQYELEGLVKGLSSLLTKNGAELLKYEYWGLLDFAYTIDKMNKGHYCMIYIKATPSSMDEFKRKVRLNEDILRFLCLKKDKLPKGDSLMIQASQV
Binds together with S18 to 16S ribosomal RNA.
Q2GHF4
Q5YTA2
DXS_NOCFA
1-deoxyxylulose-5-phosphate synthase
Nocardia
MGVLSRVDTPEDVRRLNVAELRELAEEIREFLVRKVAATGGHLGPNLGVVELTIALHRVFDSPADPLIFDTGHQAYVHKILTGRKDRFDDLRKQGGLSGYPSRAESPHDWVESSHASAALSYADGLAKAFALGGQDRHVVAVVGDGALTGGMCWEALNNIAAAPDRPVVVVVNDNGRSYAPTIGGLADRLTALRTQPAYEHALDAGKRLLKSIPRVGESAYSMVHAVKAGIKDAVSPQELFSDLGLKYVGPVDGHDVVAMESALRRAKDFGGPVVVHAVTQKGRGYEHAENHVADQMHACDPIDPLTGRPLGGAKARGWTSVFSEELIEHARRRSDIVAITAAMPGPTGLSAFGERFPDRMFDVGIAEQHAMASAAGLALGGMHPVVAIYSTFLNRAFDQLLMDVALLKQPVTVVLDRAGITGPDGASHNGMWDLSLLGIIPGIRVAAPRDAATLREELGEALAVTDGPTVLRFPKGSVAEDLTAVERIDGVDVLRAADPESAVRTQRGDVLIVAVGPFARIGLAAAELLAPEGVSVTVVDPRWVLPVSDTVVKLAENYRLVVTLEDSGLHGGIGSTVSARLRSVGLDVPTRDLGVPQQFLDHASRDQVLEQLGLTPTDVARRIAGWLDAR
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
Q5YTA2
Q58522
VAPB3_METJA
Putative antitoxin VapB3
Methanocaldococcus
MINMATITIDDDVYKELLKLKGRKSVSEFIKELLEERKRKNLDVFMIAFGSRSEEDVEKLKKELKEAEKWMQSLIQV
Possibly the antitoxin component of a type II toxin-antitoxin (TA) system. Its cognate toxin is VapC3 (Potential).
Q58522
Q93ZX1
RFC4_ARATH
Protein EMBRYO DEFECTIVE 1968
Arabidopsis
MAPVLQSSQPWVEKYRPKQVKDVAHQEEVVRVLTNTLQTADCPHMLFYGPPGTGKTTTALAIAHQLFGPELYKSRVLELNASDDRGINVVRTKIKDFAAVAVGSNHRQSGYPCPSFKIIILDEADSMTEDAQNALRRTMETYSKVTRFFFICNYISRIIEPLASRCAKFRFKPLSEEVMSNRILHICNEEGLSLDGEALSTLSSISQGDLRRAITYLQSATRLFGSTITSTDLLNVSGVVPLEVVNKLFTACKSGDFDIANKEVDNIVAEGYPASQIINQLFDIVAEADSDITDMQKAKICKCLAETDKRLVDGADEYLQLLDVASSTICALSEMAQDF
May be involved in DNA replication and thus regulate cell proliferation.
Q93ZX1
Q7NZ33
HSCA_CHRVO
Chaperone protein HscA homolog
Chromobacterium
MALLQIAEPGLSAAPHQHRLAVGIDLGTTNSLVATVRSGSAAVLPDETGRSLLPSVVRYGDQGVLAVGYDAQKEQNRDPHNTIVSVKRFMGRGVSDIKDAGSLPYRFVDAPGMVQLVTRAGVKSPVEVSSDILRALKERAEASLGGELTGAVITVPAYFDDAQRQATKDAARLAGLNVLRLLNEPTAAAIAYGLDNGSEGTYVVYDLGGGTLDVSILKLTRGVFEVLATSGDSALGGDDFDHRVFCWLLEQAGVTAPSAHDMRLLHTRAREAKEALTDHASTRVTAILSDGQSLDLELDQATLHAITKTLVDKTLTPVRKALRDAKIAPEDIQGVVMVGGATRMPHVQKAVADYFGRAPLTNLDPDKVVALGAAIQANVLAGNKQDDEWLLLDVLPLSLGIETMGGLTEKIIPRNSTIPVARAQDFTTFKDGQTAMSIHVLQGERELVSDCRSLAKFTLTGIPPMVAGAARIRITFQVDADGLLSVTAREQTSGVESSIEVKPSYGLSDDEISRMLSESLANVQEDIEARKLREAIVDAESLRDATLNALAQDGDLLDQAERAEVEAAVAAVASAIAEGVTRRVNEASAALNHATETFASRRMDRNIQRALKGHKITDL
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
Q7NZ33
Q55BD5
CSN7_DICDI
COP9 signalosome complex subunit 7
Dictyostelium
MTTQQETLTDGNALKQFVVLAKSSKGRAIVSIIEKALNHPSVFVFGELLDMPNVQQLKETEFKNYYDLLLIFAYGSFIDYKNKKDSLPQLTPQMITKLKQLTIVFLSSTSNVIPYSVLQEQIEITNVRELEDLIIDSIYQNIIKGKLDQKNKHLEIDFSIGRDVQPEQLDSMINCLNNWSSTSQKLLDDISGLITHSDKVHLQYRKEKEEFESKFEIAKLNTKNDSPAEQLYYDSMEYSDEVRMKKGPKIKGKDYNKRP
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of E3 ligase complexes, leading to modify the Ubl ligase activity.
Q55BD5
P16312
PEPT1_DERMI
Major mite fecal allergen Der m 1
Dermatophagoides
TQACRINSGNVPSELDLRSLRTVTPIRMQG
Thiol protease that hydrolyzes proteins, with a preference for Phe or basic residues.
P16312
A6LPQ0
RL11_CLOB8
50S ribosomal protein L11
Clostridium
MAKKVTGMIKLQLQAGKATPAPPVGPALGQHGVNIMGFCKEFNAKTANQAGYIIPVVITVYQDRSFSFILKTPPAAVLIKKEIGLESGSGVPNKTKVGKLTQDQLKKIAETKMPDLNAASLESAMRMIAGTARSMGVTIEE
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
A6LPQ0
Q0SNH3
RL13_BORAP
50S ribosomal protein L13
Borreliella
MNKITNNVTIWIKPKTVEKKWYVIDAADRVLGKVAVDVVRILRGKHKAYYTPHQDLGDNVIVINASKVRLTGKKYQQKLYYRHSRYPGGLYSDTFRTLSERKPCAPLEIAIKGMLPKGPLGRGLFRNLKVFSGSEHTLKAQNPVKLEANLER
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
Q0SNH3
B1IKX1
LDH_CLOBK
L-lactate dehydrogenase
Clostridium
MIKKRNTTKISVIGAGSVGATTAYALMLSGVATEIVLVDVNKAKTEGEAMDLSHGADFVKPVNILSGDYKDTEGSDIVVITAGAAQKVGETRLQLINKNINIFKSIIPEVVKYNKDAILLVVSNPVDVLSYVTYKLSGFPKERVIGSGTVLDTSRLKHEIGKRYKIDPRNVNTYIMGEHGDSEIATWSVTNIQNIKIDEYANKENLEYNDNFRKEVYENVKNAAYEVINRKGATFYAIALAVTRIVKAILGDEKTILPVSTLVENYYGIKDVYLGMPCIVGGSGIEKALSIDLNKTEASKLVKSAETLKNTLNNASGL
Catalyzes the conversion of lactate to pyruvate.
B1IKX1
Q6BIH5
FYV4_DEBHA
Protein FYV4, mitochondrial
Debaryomyces
MSFRLFARPLIQMPKLAAPRCINITPIRPISASAISLKTNTSTSTKENVHDLETFFKLIGRDCIEHLDAFESDLQKFLKTSSKDMKNMGIDVSTRRYMLRWIHKFQNDLEPLREHKRGKKKNGGERNAKTVLAKRTALKRLEEKERFESQELEAERKGEREF
Involved in telomere length regulation.
Q6BIH5
P72761
CCMK2_SYNY3
Carbon dioxide-concentrating mechanism protein CcmK2
unclassified Synechocystis
MSIAVGMIETRGFPAVVEAADSMVKAARVTLVGYEKIGSGRVTVIVRGDVSEVQASVSAGIEAANRVNGGEVLSTHIIARPHENLEYVLPIRYTEEVEQFRTY
One of the shell proteins of the carboxysome, a polyhedral inclusion where RuBisCO (ribulose bisphosphate carboxylase, rbcL-rbcS) is sequestered. The central pore probably regulates metabolite flux . Hexamers make sheets that form the facets of the polyhedral carboxysome (Probable) .
P72761
P82536
TLP20_SPIOL
Thylakoid lumenal 18 kDa protein
Spinacia
SAEETPLQSKVTNKVYFDISIGNPVGKVVIGLFGDDVPQTAENFR
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
P82536
Q5HRS7
RECR_STAEQ
Recombination protein RecR
Staphylococcus
MHYPEPISKLIDSFMKLPGIGPKTAQRLAFHTLDMKEDDVVKFAKALVDVKRELTYCSVCGHITENDPCYICEDKQRDRSVICVVEDDKDVIAMEKMREYKGLYHVLHGSISPMDGIGPEDINIPALVERLKNDEVKELILAMNPNLEGESTAMYISRLVKPIGIKVTRLAQGLSVGGDLEYADEVTLSKAIAGRTEM
May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
Q5HRS7
Q67NB6
DXS_SYMTH
1-deoxyxylulose-5-phosphate synthase
Symbiobacterium
MHLRDLTGPEQLKRLAPAELAQLAAEIRRVILETVATNGGHLAPNLGVVELTLALHIVFDSPRDKILWDVSHQSYVHKLLTGRLHQFHTLRQFGGIAGFTDPRESVHDHFHWGHASTSISAAVGMAKARDLAGDDYEVVAVIGDGALTGGMAYEALDHAGHDKTKVIVVLNDNSMSIAPNVGGISNYLARIRTGPSYQRVKHDVAEALRQIPLIGPQALELADRLKEGVKHLLVHNMFFEDLGFTYLGPVDGHNVSALVDVLRQARAYPGPTVVHVVTTKGKGVPYAEQLPDKFHGGGPFDVATGRTGPGSLTYSEVFGNVMCKLAAEDPRVCAITAAMPSGTGLSRFARQFPDRYFDVGIAEQHAVTFAAGLAKGGMRPVFAVYSTFLQRAYDQVIHDVALQNLPVTLAIDRGGLVEDGATHQGVFDVAYLRAIPNMVVMAPKDENELQHMLYTALCHDGPAALRYPRGKAQGVPLDETLQPLPIGRGEVMQEGADVALIGLGTMARVCQEAARLLAEKSISAMVINPRFVKPLDAELLLRAGREVGAVVTVEEACLAGGFGSAVLELYAAHGVNARVERMGIPDEFVDHGQPARYLERYGLTPEGVAQRAEALLLRMRSDLAAQPARRSRSVRRLSGAKAAGNGET
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
Q67NB6
Q81IS8
TSAD_BACCR
tRNA threonylcarbamoyladenosine biosynthesis protein TsaD
Bacillus cereus group
MGEYIMEKNTIILGIETSCDETAVAVVKNGTEIIANVVASQIESHKRFGGVVPEIASRHHVEEITVVLEEALKEANITFDDIDAIAVTEGPGLVGALLIGVNAAKAVAFAHDIPLVGVHHIAGHIYANRLVKEVQFPLLSLVVSGGHTELVYMKEHGSFEVIGETRDDAAGEAYDKVARTLSMPYPGGPHIDRLAHEGEPTIDLPRAWLEPDSYDFSFSGLKSAVINTVHNAKQRGIEIAPEDLAASFQESVIDVLVTKAARAAEAYNVKQLLLAGGVAANKGLRARLEEEFAQKENIELIIPPLSLCTDNAAMIAAAGTIAYEQGKRATLALNANPGLDIEA
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.
Q81IS8
B5BCP4
ARNT_SALPK
Undecaprenyl phosphate-alpha-L-Ara4N transferase
Salmonella
MMKSIRYYLAFTAFIALYYVIPVNSRLLWQPDETRYAEISREMLASGDWIVPHFLGLRYFEKPIAGYWINSLGQWLFGATNFGVRAGAILTTLLAAALVAWLTFRLWRDKRTALLASVIFLSLFAVYSIGTYAVLDPMIALWLTAGMCCFWQGMQATTRTGKIGMFLLLGATCGLGVLTKGFLALAVPVVSVLPWVIVQKRWKDFLLYGWLAVLSCFVVVLPWAIAIARREADFWHYFFWVEHIQRFAMSDAQHKAPFWYYLPVLLAGSLPWLGLLPGALKLGWRERNGAFYLLGWTIMPLLFFSIAKGKLPTYVLSCFAPIAILMARFVLHNVKEGVAALRVNGGINLVFGIIGIVAAFVVSSWGPLKSPVWTHIETYKVFCVWGVFTVWAFVGWYSLCHSPKYLLPAFCPLGLALLFGFSVPDRVMESKQPQFFVEMTQAPLASSRYILADSVGVAAGLAWSLKRDDIMLYGHAGELRYGLSYPDVQNKFVKADDFNAWLNQHRQEGIITLVLSIDKDEDISALSLPPADNVDYQGRLVLIQYRPK
Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
B5BCP4
A0A2A5K485
AZG2_PAELB
Nucleobase transporter PlAzg2
Paenibacillus
MYVSSLLFLYASESYESFIFHFQMCYNKAHNGFMPSIFQQLKGLGEGLQWKVGISLDHQEKQTSSHEKEMTSPNSATRLIPSDWRRELLAGTVSFFAAVYIIIVNSSILADAGIPQEAGIIATILASAIGCFIMGLWGNAPLVIVPGMGINAMFTYTLVQGMGLTWQQALAAVMMSGICFFAISMTSLVEKLRTAIPASLQEAISVGIGLMLVLIGLHKGGVIASDRSSVIAVQSFADPGVLVTLATLALTCILYIRKVPGNLLLAIIGGSALAYLFKAVPSKAATGVGGSSWSSYGDLFGQLSVKGASITTLVIAVFSLTLVIVFENVGLINAQLKMSGRTERFKRVTQATSLTVILSGIFGTSPTVSTVEAAAGISAGGRTGWASIATGTLFLLSFIAMPVITLVPDQAVAPILIFIGGLMMPAVRHISFERMEEGLPAFFIIAFIPLMHSIVDGIAIGFISYALFHIAVGKWREVKPLFYIISLLFVMHFVLQTM
Transports adenine, guanine, hypoxanthine, xanthine, cytosine and uracil. Transport is probably proton-dependent.
A0A2A5K485
A5ILC9
RPOZ_THEP1
Transcriptase subunit omega
Thermotoga
MEKMVKFNLRYDELLKKIPYKYAIPVVVAKRAEAIREYAKPFVITDDENPVSIAFMELSLNYIRIKNEEILKALIPKVK
Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
A5ILC9
A5E2R6
CIAO1_LODEL
Probable cytosolic iron-sulfur protein assembly protein 1
Lodderomyces
MKLLHSIKAHDDKVWSLSSHPTLPLLATASTDKCSNIYRLSCSNASSSSSSSSPPSPPSPPSSSSPRRNFPQIAHLEDTHRRSVRSVSFKPPMGGIDHQDSNILDLPALASGSFDSTISIWGIDEPDDDNTYEIEEIIANQKEFLASPGNEWNLMAVIEGHENEIKAVDWNFSGRYLASCSRDKTVWIWETDPETLEEFECVAVLTDHTQDVKHVTWHPTRNLLASSSYDDTIRVYKQEFDDDEWSCVGMIDGHEGTVWCSKFESPKSPKAKDGTTRLVSVSDDLSARVWASKDNTGFNGGSEQLQSQSQTHLPSSIRHNAEEMVWEQESTLPQIHTHAIYSVAWSSSSGKIATAGSDGRIVVYKETNAGWEVENIQESAHGVYEINCVIWAKLDLDQEVLISGGDDGNVNIWEV
Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins.
A5E2R6
O82616
SCRK5_ARATH
Probable fructokinase-5
Arabidopsis
MANTPLIVSFGEMLIDFVPDTSGVSLAESTGFLKAPGGAPANVACAITKLGGKSAFIGKFGDDEFGHMLVNILKKNGVNSEGVCFDTNARTALAFVTLKKDGEREFMFYRNPSADMLLKESELNKDLIKKAKIFHYGSISLISEPCRTAHMAAMKTAKDAGVLLSYDPNVRLPLWPSTEAAIEGIKSIWNEADIIKVSDDEVTFLTRGDAEKDDVVLSLMHDKLKLLIVTDGEKGCRYYTKKFKGRVPGYAVKAVDTTGAGDSFVGAFLVSLGKDGSILDDEGKLKEALAFANACGAVCTTQKGAIPALPTPADAQKLMKSKSK
May play an important role in maintaining the flux of carbon towards starch formation.
O82616
A8MJJ8
CH10_ALKOO
Chaperonin-10
Alkaliphilus
MNIKPLGDRVVIKRVEAEETTKSGIVLPGSAKEQPQLAEVMAVGPGGVIEGKEVVMEVKVGDKVIFSKYAGTEVKFDGVEYTILKQSDILAVVE
Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
A8MJJ8
Q9D513
MEIOB_MOUSE
Protein expressed in male leptotene and zygotene spermatocytes 675
Mus
MAKFFALKNFTALSDLHPNMANLKIIGIVIGKTDVKGFPDRKNIGSERYTFSFTIRDSPCHFVNVSSWGSEDYIRSLSESFRVAECVIIENPLIQRKDTEREEKFSPATPSNYKLLLSENHSMVKVCSPYEVDTKLLSLIHLPVKESRDYYSLADIVANGHSLDGRIINVLAAVRSVGEPKYFTTSDRRKGQRCEVKLFDETEPSFTMTCWDNESILLAQSWMARETVIFASDVRINFNKFQNCMAATVISKTIITVNPDTPEANILLNYIRENKETNVADEIDSYLKESVNLNTIVDVYTVEQLKVKALKSEGKADPFYGILYAYISTLNIDDETTKVVRNRCSSCGYIVNEASNTCTICNQDSSRLKSFFLSFDVLVDLTDHTGTLHSCSLSGSIAEETLGCTINEFLTMTSEQKTKLKWQLLLERSKIYLKLILSHRARGGLKVTILSCKLADPTEASRNLARQGHT
Single-stranded DNA-binding protein required for homologous recombination in meiosis I. Required for double strand breaks (DSBs) repair and crossover formation and promotion of faithful and complete synapsis. Not required for the initial loading of recombinases but required to maintain a proper number of RAD51 and DMC1 foci after the zygotene stage. May act by ensuring the stabilization of recombinases, which is required for successful homology search and meiotic recombination. Displays Single-stranded DNA 3'-5' exonuclease activity in vitro.
Q9D513
Q03PV7
RL3_LEVBA
50S ribosomal protein L3
Levilactobacillus
MTTKGILGKKVGMTQVFTDAGELIPVTVVEATPNVVLQVKTMENDGYNAIQLGYQDKREVLSNKPEQGHVAKANTTPKRFIREFTDVELGDYKVADEVKVDTFQAGDIVDVTGVTKGHGYQGNIHKDGQSRGPMAHGSRYHRRPGSLGAIINRVFPGMKLPGRMGNKQVTIQNLVIVKADVENNVLLIKGNVPGANKSLVTVKSAVRPPRPKQSEK
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
Q03PV7
Q6GUG4
P2Y13_RAT
P2Y purinoceptor 13
Rattus
MLGTVNTTGMQGFNKSERCPRDTRMTQLLFPVLYTVVFFTGVLLNTLALWVFIHIPSNSTFIIYLKNTLVADLIMTLMLPFKILSDSRLAPWQLRGFVCTFSSVVFYETMYVGIMMLGLIAFDRFLKIVVPFRKTFVKKTAFAKIVSISIWLLMFLISLPNMILNKEATASTVKKCASLKSPLGLLWHQVVSHTCQFIFWTVFILMLLFYTVIAKKVYDSYRKFKSRDSKHKRLEAKVFIVMAVFFVCFAPFHFVRVPYTHSQTTNKTDCRLENQLFLAKESTLFLATTNICMDPLIYIILCKKFTRKVPCMRWRTKTAASSDEHHSSQTDNITLS
Receptor for ADP. Coupled to G(i)-proteins. May play a role in hematopoiesis and the immune system.
Q6GUG4
A3QCH0
GUAA_SHELP
Glutamine amidotransferase
Shewanella
MSNIHDHKILILDFGSQYTQLIARRIREIGVYCELWAWDVSEEQIKAFAPNGIILAGGPESVTADNSPRAPEYVFNAGVPVLGICYGMQTMSEQLGGKVIQGVGEGEFGYAQVEVQAASELFKSIEDAVSDSGKALLDVWMSHGDKVSEIPEGFVTVAKTDTCPYAAMANEEKRFYGVQFHPEVTHTRQGKRMLEHFALDICQCEANWKPSSIIEDAVARIKEQVGDDEVILGLSGGVDSSVVAMLLHRAIGSKLTCVFVDNGLLRLNEADQVLEMFGDHFGLNIVHVDAESRFLDALAGEAEPEAKRKIIGKVFVDIFDEESRKCVNAKWLAQGTIYPDVIESAGSATGKAHVIKSHHNVGGLPDDMELGLVEPLRELFKDEVRKIGLELGLPYNMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELHKADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPYDFLGRVSNRIINEIDGISRVVYDISGKPPATIEWE
Catalyzes the synthesis of GMP from XMP.
A3QCH0
A1BBM5
4HYPE_PARDP
4-hydroxyproline 2-epimerase
Paracoccus
MTQYIFPCIDGHTCGNPVRLVAGGAPRLEGATMLEKRAHFLREFDWIRTGLMFEPRGHDMMSGAILYPPTRGDCDVAVLYIETSGCLPMCGHGTIGTITMGIENGLIVPRTPGRLSIETPAGKVDIEYRQEGRHVEEVRLTNVPGFLYAEGLTAEVEGLGEIVVDVAYGGNFYAIVEPQKNFRDMADHTAGELIGWSLTLRAALNQKYEFTHPEHPQINGLSHIQWTGAPTVPGAHARNAVFYGDKAIDRSPCGTGTSARMAQLAARGRLGVGDEFWHESIIGSIFKGRIEAAATVAGRDAIIPSIAGWARQTGLNTIFIDAERDPFAHGFVVK
Catalyzes the epimerization of trans-4-hydroxy-L-proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp). Is likely involved in a degradation pathway that converts t4LHyp to alpha-ketoglutarate, which would allow P.denitrificans to grow on t4LHyp as a sole carbon source . Also seems to be involved in an alternative catabolic pathway that degrades trans-4-hydroxy-L-proline betaine (tHyp-B) to alpha-ketoglutarate; this pathway would permit the utilization of tHyp-B as a sole carbon and nitrogen source .
A1BBM5
A0A172M490
RLR63_PLAVT
Secreted RxLR effector protein 63
Plasmopara
MQRFPYSLLLLLLSATNRSRRHHITRPGRSIHWCLVRPTRPNRMLRAIRTCGARYWRNWPLNWPRKAGLTRRSSARIGLSDALRPCPTLFGCFKRRYARQAMSCYCRTEWRVNWLKKKRRGSSRWRRESSVWRCWK
Effector that partially suppresses the tobacco programmed cell death induced by cell death-inducing proteins.
A0A172M490
Q8CXR2
MTAP_LEPIN
5'-methylthioadenosine phosphorylase
Leptospira
MSYNVRAAIIGGTGLYSLEGMELIEEIFPDTPWGKPSDKIKIGKYKGKLIAFLPRHGIGHFLSPPEVPNHANICALKQLGVEEIVAFSSVGSLREEIKPLDFVLPSQIIDRTRFRNSTYFGNGVVAHAPFAEPFSPNLSKRIAQTAKKIGLEIHLDKTLVCMEGPLFSTKAESHLYRSWGADIINMTVLPEAKLAREAEIAYQMICMSTDYDCWREGEESVTVEMVIANLTKNAETAKKLLSELIHVLGNGDDLSLKNSTRYSIITAPEKRNSETVKKLRVLFPEYF
Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
Q8CXR2
A9MF27
FTSB_SALAR
Cell division protein FtsB
Salmonella
MGKLTLLLLALLVWLQYSLWFGKNGIHDYSRVNDDVVAQQATNAKLKARNDQLFAEIDDLNGGQEAIEERARNELSMTKPGETFYRLVPDASKRAQTAGQNNR
Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
A9MF27
Q4JUI9
RF1_CORJK
Peptide chain release factor 1
Corynebacterium
MSQSPSVIDDILAEYQGLEMQLSDPELHNDPAAARKVGKRFSELQPIIQTHQKLEQAREDQEAASEMASEDKEFAEEAKRLEEEISELEEQLTDLLAPRDPHDGDDIVMEIKSGAGGEEAALFAGELARMYQRYAERHGFSTEILGLNETDLGGVKDMTLSIRSKQPSRDGAWSEFKFEGGVHRVQRIPVTESQGRIQTSAAGVLVYPEPDEVEDVHIDDKDIRVDVYRSSGKGGQGVNTTDSAVRITHLPTNIVVTCQKERSQIQNRARAMQVLAARLQQLKEEEAEAEAAEGRAAQIRTMDRSERIRTYNFPESRVSDHRIGYKANNLDSVLDGDLEALLAALKEADRARRLEAED
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
Q4JUI9
A0L2B4
MEND_SHESA
Menaquinone biosynthesis protein MenD
Shewanella
MRTENTATLNLMWGALILEELARLGVQHVCMAPGSRSTPLTLAAAQQTKLKRHLHFDERGLGFMALGLAKASCAPVAIITTSGTAVANLYPAIVEAWLTHVPLIVLSGDRPPELLGCGANQAIVQPAIFANYAQQVNLPTPDAHIAPQMLLTTLDEAVANQTRPVHINCMYREPLYPSEMSGTILDSESPYLRPLQTWLQHAKPYTQYGKSEQLSSPSDDAIMRFVHGKGVIIAGTLTPEQDPQQLIALSQKIGWPLLTDAQSQLRQHPAAIGNIDQLLQHPKARNLLQEADRVLVFGGRLLSKRLIAYLAEQNWHSYWQVLPQQDRLDPSHNAKHIWHANAAQFAQLNWYRSSSANWANTLVTYNDELHSLFVRNIDQGEFGEAQVIRAIANTRPLEQQLFIGNSLPVRLYDMYAPVSCCTATTYTNRGASGIDGLLATACGIAAHQGKPTSLIIGDLSQLHDLNSFAIARSLTSPLVIIILNNDGGNIFNLLPVPNEELRSDYYRLSHGLEFGYAAAMFNLPYNQVDNLADFQSCYHEALDYQGASVIEVSVSQHQASEQIAALNLWVKQS
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
A0L2B4
P56936
REPA1_BUCAI
Probable replication-associated protein repA1
Buchnera
MIIRKCYINNPNPFFTPPKNNKRRPSFICYAMKRASEIDVARCELNYILQIKNIKIGFPVKRFRRLNEHRACAMRAMVLAMLYHFNISSDLVQASVEQLSDECGLSTLSKAGNKSITRASRLITNFMEPMGFVTCKKTWDKILGNYMPKMITLTPLFFMLFGVSEKKLMDAKKQQLGWINKNLISKGFKPITMIDAKRRSKDTQIKNIFQYRISKHAFYKKKRNAQRLISLDEKEARQTILRALVAKYSITELTKLGPNGLKKQVNISYYYLRKIATNTYPDN
This protein is essential for plasmid replication; it is involved in copy control functions.
P56936
Q10MI9
NAS2_ORYSJ
S-adenosyl-L-methionine:S-adenosyl-L-methionine:S-adenosyl-methionine 3-amino-3-carboxypropyltransferase 2
Oryza sativa
MEAQNQEVAALVEKIAGLHAAISKLPSLSPSAEVDALFTDLVTACVPASPVDVAKLGPEAQAMREELIRLCSAAEGHLEAHYADMLAAFDNPLDHLARFPYYGNYVNLSKLEYDLLVRYVPGIAPTRVAFVGSGPLPFSSLVLAAHHLPDAVFDNYDRCGAANERARRLFRGADEGLGARMAFHTADVATLTGELGAYDVVFLAALVGMAAEEKAGVIAHLGAHMADGAALVVRSAHGARGFLYPIVDLEDIRRGGFDVLAVYHPDDEVINSVIVARKADPRRGGGLAGARGAVPVVSPPCKCCKMEAAAGAFQKAEEFAAKRLSV
Synthesizes nicotianamine, a polyamine that is the first intermediate in the synthesis of the phytosiderophores of the mugineic acid type found in gramineae which serve as a sensor for the physiological iron status within the plant, and/or might be involved in the transport of iron.
Q10MI9
Q0AUG8
RL1_SYNWW
50S ribosomal protein L1
Syntrophomonas
MKRGKNYQQAGEKFDRLTLYEPKEALELVKEIAKAKFDETVEVHIKLGVDPRHADQQVRGTVSLPNGTGKTRKVLVFAKGEKIKEAELAGADYVGGEDLAEKIQGGWFDFDVAVATPDMMAVVGKMGKILGPRGLMPNPKAGTVTFDIERTIKELKAGRIEYRVDKSAIVHAPIGRISFEVDKLQENLNAFAEALLKARPAAAKGQYMRSVTVCSTMSPGVKINPLVLMAANK
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
Q0AUG8
Q12D54
PPNP_POLSJ
Xanthosine phosphorylase
unclassified Polaromonas
MITEKIDNISVTTKANVYFDGKCVSHGITFTDGTKKSVGVILPATLTFNTGAPEIMECVAGACEYRLAGSDSWVKSAAGEKFSVPGNAKFDIRVAEGFEAYHYICHFG
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.
Q12D54
P01418
3S11_DENVI
Neurotoxin 4.11.3
Dendroaspis
RICYNHQSTTPATTKSCGENSCYKKTWSDHRGTIIERGCGCPKVKRGVHLHCCQSDKCNN
Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission.
P01418
C3KCS7
MRAY_PSEFS
UDP-MurNAc-pentapeptide phosphotransferase
Pseudomonas
MLLLLAEYLQQFHKGFAVFQYLTLRGILGVLTALCLSLFLGPWMIRTLQNLQIGQSVRNDGPQSHLSKSGTPTMGGALILSSIGISTLLWADLHNRYVWVVLLVTLLFGAIGWVDDYRKVIEKNSKGLPSRWKYFWQSVFGVGAAIFLYTTAPSAVETTLIIPMLKDASIPLGIGFVVLTYFVIVGSSNAVNLTDGLDGLAIMPTVMVGGALGIFCYLSGNVKFAEYLLIPYVPGAGELIVFCGALIGAGLGFLWFNTYPAQVFMGDVGALALGAALGTIAVIVRQEIVLFIMGGVFVMETLSVVIQVASFKLTGRRVFRMAPIHHHFELKGWPEPRVIVRFWIITVILVLVGLATLKLR
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
C3KCS7
B4U769
RS13_HYDS0
30S ribosomal protein S13
unclassified Hydrogenobaculum
MARIAGVDLPDHKKLEVALTYIYGIGWSKAREVCEQTGIPSIKKLGELTPEELNQLRRYIEQNIKVEGDLRREVQLNIKRLVDIGTYRGLRHVRGLPVRGQQTKTNARTRKGRRKGTVANKKKVSK
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
B4U769
P34477
UBC7_CAEEL
Ubiquitin-protein ligase 7
Caenorhabditis
MEQSSLLLKKQLADMRRVPVDGFSAGLVDDNDIYKWEVLVIGPPDTLYEGGFFKAILDFPRDYPQKPPKMKFISEIWHPNIDKEGNVCISILHDPGDDKWGYERPEERWLPVHTVETILLSVISMLTDPNFESPANVDAAKMQRENYAEFKKKVAQCVRRSQEE
Catalyzes the covalent attachment of ubiquitin to other proteins.
P34477
B4R8N3
RL18_PHEZH
50S ribosomal protein L18
Phenylobacterium
MALSPRDTTKRRAQRVRTRLRKVANGRPRLSVFRSAKNIYAQVIDDERGVTLAAASSLEGEKKDKGSDKDAAARVGALVAQRAIEKGVKDVVFDRGGYLYHGRVKALADAAREAGLNF
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
B4R8N3
Q54GQ1
MTMR_DICDI
Myotubularin-related protein DDB_G0290005
Dictyostelium
MFSNKNTDNVENDNNNALGSVIARINSQNIITKNKAPVISEDFETQDFDYPSFDDETPNYDRPQPTMVENFTLLPGEFVLMITKNVVNLSLTTTTHRIGTLYQTNYQMFFIDDSTRQLVSTIANGQLLQIKKLKGHVTVKYHDNTTPNNNNNNNNNNNNNNNNTNNNNNNNINKSNNSSTDQLNSFSLEKQPSQNENLNNNNNNNNNNNNGNNNINNNNLMNSLTQPSTSSRSRLLKSNSTPINLNESSTSTNSPTLSSTTTTTTTTSSTNGNCSTNTWYSNGVSEKALILEIRCKDFMITRYCLPFNEKGNEAFELMNKLICNNYQDSNQLFSMSYSPFKGVISPIDGWLFYDPIEEYTRQGLIGNSNGSDEWRLTKMNSKYELCSTYPQHFIIPFSISDYLLNKSSSHRNKNRFPVVTWRHKQTHATLSRSSQQTGKSRCEEDELLIQAIRKSKTILPNNNNQQQQPQQQQQTLYIIDIKSTSSSPTSSSSSHCEDISHYSQCQIESECLSNIHELRESQLKLFKVIRNWNEKKGWSEIQSTGWLDQLSKLLMVTKKILTHLHLEGFSCLIHCIDGWDRTCQLSSLVQLCADPYYRTIKGFIVLISKEWLSFGHKFMTRNGQSISSTSTTTTNSSSNGQLTSSSSNTSISSNATTTTTTTTSSKQTSPVFLQFIDVVWQLTKQFPTSFEFSDSFLSVILHHLNSNLFGTFLYDSEKERQQNNLPTETQSLWTLLLSAQKNSSLLNPLFNQQLSNETSSTTNLTATTSIPLTNSTTLDQQLQFKNNNDDGVLFPNPKGVQLWSDYFLKWRNPPKASRKSNTLIAHSLGVSYVNGDLIAFQKKKRSRRSKDGASGSSSGSSGSSSKHHHHHHHHHHHHHHRKSTDEKDSKEKSSKSSRSRTSSSSKRKSLSTSSNSITQPDIKINETITTTTTTPTNTTTLTNTSTTPRNTTTLTNASTTPTTTTTTTTTTTPTKDETINESVQVNNDKLKSPSGDDIKQEQDEMNQFTSQHPNNQMESSSEINQQNEQSQLEQQQEQQQQQEQQLQHEQQQIEQQQLQKQQQQQEQQEQQELEQQEQPNETITYSMESDSQSSISQNQNQLQQQQQQQTLLDPIDESSLLATTTTTTSSTAITSASKLEKELRKQEKEKRKLEKEKKQKERAERKLEKEKKRDQKEREQKEKELLEQQKPKADITVVLQSPSKKKAMSLTMPVRGTKSRISIFSSPLVPTLHPNLSDQNSQTNSSGDNSGNVNNSPNLTSTPISNLSNNNNNNNNSNENSNNNNNNNNNNNDNTSFSKRIFKTLRGTKTFNREPTPTVGTALN
Phosphatase that acts on lipids with a phosphoinositol headgroup.
Q54GQ1
Q6P632
NAA20_XENTR
NatB catalytic subunit
Silurana
MTSLRPFTCDDLFRFNNINLDPLTETYGIPFYLQYLAHWPEYFIVAEAPGGELMGYIMGKAEGSVAREEWHGHVTALSVAPEFRRLGLAAKLMELLEEISERKGGFFVDLFVRVSNQVAVNMYKQLGYSVYRTVIEYYSASNGEPDEDAYDMRKALSRDTEKKSIVPLPHPVRPEDIE
Catalytic subunit of the NatB complex which catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Asp, Met-Glu, Met-Asn and Met-Gln. Proteins with cell cycle functions are overrepresented in the pool of NatB substrates. Required for maintaining the structure and function of actomyosin fibers and for proper cellular migration.
Q6P632
Q975J3
RL5_SULTO
50S ribosomal protein L5
Sulfurisphaera
MAETQTVNPMRKLRLEKVTVNIGVGEAGERLQKAYQLLQELTGVKPVYTIAKRTIREFGVRKGAPIGVKVTLRGKKAEEFLNKVLAAVGHRIKASSFDEYGNVSFGIAEHVLIPGTRYDPEIGIFGMDVAITLVRPGFRVARRRRKKAHIPKRHRTVSKEEAMEFLKQNFNVTIVEG
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
Q975J3
A0JWY7
PSA_ARTS2
Proteasome core protein PrcA
Arthrobacter
MTQQFYVSPEQLMKDRADFARKGIARGRSVVVISCEEGIALVAENPSPSLHKIGEIYDKIAFAAVGKYNEFESLRQAGVRYADVRGYSYDREDVTARGLASVYAQSLGAVFTAEQKPFEVELAVAEVGGNQSDDHLYRLTFDGSIADEKRFIVMGGQADKVAETVEGGWQQELNFAGAIRLAMKGLVTDKEAGELPASALEVAVLDRASESTRGSRRAFRRLGDDEIAALLSKEN
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
A0JWY7
Q8X823
BIOF_ECO57
8-amino-7-ketopelargonate synthase
Escherichia
MSWQEKINAALDARRAADALRRRYPVAQGAGRWLVADDRQYLNFSSNDYLGLSHHPQIIRAWKQGAEQFGVGSGGSGHVSGYSVAHQALEEELAEWLGYSRALLFISGFAANQAVIAAMMAKEDRIVADRLSHASLLEAASLSPSQLRRFVHNDVTHLARLLASPCPGQQLVVTEGVFSMDGDSAPLAEIQQVTQQHNGWLMVDDAHGTGVIGEQGRGTCWLQKVKPELLVVTFGKGFGVSGAAVLCSSTVADYLLQFARHLIYSTSMPPAQAQALRASLAVIRSDEGDARREKLAALITRFRAGVQDLPFTLADSCSAIQPLIVGDNSRALQLAEKLRQQGCWVTAIRPPTVPSGTARLRLTLTAAHEMQDIDRLLEVLHGNG
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
Q8X823
B6IVF3
RIMP_RHOCS
Ribosome maturation factor RimP
Rhodospirillum
MEAVERIGRIIEPSVEAMGYELVRVQLSGGQRPTLQIMAERSDGAAMTVEDCADISRAVSALLDVEDPLPGAYTLEVSSPGIDRPLTRLKDFERFAGFEARLETKAPVDGRKRFRGFLAGIEDDAVRLALPVEKKARKGAKAAPTRDAADAGEAGDAEATLVVIPFGLVLKAKLELTDELLTAAAAEQGAAPGTEGGAMEVEEDARPARRPHQPKPKKAKKKGPGRFSKAGAGEDVDGADGGPAAGPGAQDE
Required for maturation of 30S ribosomal subunits.
B6IVF3
Q32HR2
CBPA_SHIDS
Curved DNA-binding protein
Shigella
MELKDYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKEPDAEAHFKEVAEAWEVLSDEQRRAEYDQMWQHRNDPQFNRQFHHSDGQSFNAEDFDDIFSSIFGQHARQSRQRPAARGHDIEIEVAVFLEETLTEHKRTISYNLPVYNAFGMIEQEIPKTLNVKIPAGVGNGQRIRLKGQGTPGENGGPNGDLWLVIHIAPHPLFDIVGQDLEIVVPVSPWEAALGAKVTVPTLKESILLTIPPGSQAGQRLRVKGKGLVSKKQTGDLYAVLKIVMPPKPDENTAALWQQLADAQSSFDPRKDWGKA
DNA-binding protein that preferentially recognizes a curved DNA sequence. It is probably a functional analog of DnaJ; displays overlapping activities with DnaJ, but functions under different conditions, probably acting as a molecular chaperone in an adaptive response to environmental stresses other than heat shock. Lacks autonomous chaperone activity; binds native substrates and targets them for recognition by DnaK. Its activity is inhibited by the binding of CbpM.
Q32HR2
B2FHZ1
ATPD_STRMK
F-type ATPase subunit delta
Stenotrophomonas maltophilia group
MSQALTLARPYARAAFATARDEGAFAPWSDALAFSAHVAVDPRVAALLANPELGRDDAVALLAPVSHGETYSRFLAILAESHRLPLLPEISGMFDALRAEAEHVVKATVTSAAELSAGELDAIKVALRKRFNREVDVTTAVDASLIGGAVIDAGDVVIDGSLKGKLARLQTALAN
This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
B2FHZ1
Q8U3D6
ACDA2_PYRFU
ADP-forming acetyl coenzyme A synthetase II subunit alpha
Pyrococcus
MLDYFFNPRGIAVIGASNDPKKLGYEVFKNLKEYQGGKVYPVNVREEEVQGVKAYKSVKEIPGEVDLAIIVVPKKFVKQTLIECGEKGVKGVVIITAGFGETGEEGKREEKELVEIAHKYGMRIIGPNCVGIMNTHANLNATFITVAKKGNVAFISQSGALGAGIVYKTIKEDIGFSKFISVGNMADLDFADLMEYLADTQEDKAIALYIEGIKDGRRFIEVAKKVTKKKPVIALKAGKSESGSRAAASHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQPLPKGNRVAIMTNAGGPGVLTADEIDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASARGEDYYRTAKLLLQDPNVDILIAICVVPTFAGMTPTEHAEGIIRAVKEVNNGKPVLALFMAGYVSEKAKELLEKNGIPTYERPEDVAAAAYALVQQAKNVGGGVNG
Catalyzes the reversible formation of acetate and ATP from acetyl-CoA by using ADP and phosphate. Can use other substrates such as phenylacetyl-CoA, indoleacetyl-CoA and isobutyryl-CoA, but not succinyl-CoA. Seems to be involved primarily in the degradation of aryl-CoA esters to the corresponding acids. Participates in the conversion of acetyl-CoA to acetate and in the degradation of branched-chain amino acids via branched-chain-acyl-CoA esters.
Q8U3D6
B7J4C0
ISPD_ACIF2
MEP cytidylyltransferase
Acidithiobacillus
MERVWVVIPAGGRGQRFGAAQAKQYVLLRDRPVIAHTLAAFLGEPRIAGIQLVLPGEDIATGAWRELLGPMPAPLLPPVVGGGLRADSVRLGLEALLRQGAVPSDWVLVHDAARPCLRREDLLRLLESLANAPQGALLAVPVADTLKRGEDGCSSGTVDREGLWRALTPQAFPLGALLAALEAARAGNRQITDEASAMEAQGWRPRLIPGHGDNIKVTLSDDLMLAAAILAARSEEG
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
B7J4C0
Q7VJV1
FLGI_HELHP
Basal body P-ring protein
Helicobacter
MRRKNNNKIWIWVATLILSISALYGQKINQIAQIVGIRDNSLVGYGLVIGLNGTGDKSGSKFTMQSIANMLESVNVKLSANDIKSKNVAAVMVTASLPPFARQGDKLDILVSSIGDAKSINGGTLVMTPLTGVDGNIYALAQGNITFGESGSTLSGTIIGGASVEREIAYNLYNQENATLSLKSSDLQNAIKIQQALNDVFRDAIAVAVDARTIKLKKPENLSMVEFLALVEEVEIDYSRKERIVIDEKSGTIVAGVGITIDPVVVTHGDITIKISDEMPDDPEAIKLEDGTMMSRAQGTISSTNGTKPTVSSVVKALQRMGATPRNVISILESMKKSGALNADIEVM
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
Q7VJV1
Q82S12
FPG_NITEU
DNA-(apurinic or apyrimidinic site) lyase MutM
Nitrosomonas
MPELPEVEITRRGIDTHLAGRVITQISIRNPVLRWPISAGLIALLPGQRINAIARRAKYLLFACSRGTLIMHLGMSGNLRVLPESTPPQLHDHFDLQVDNGMMLRFRDPRRFGAILWWDGDIRQHPLLQKLGPEPLSDDFDGQFLYTKTRGRNASIKEVLMNQHIVVGIGNIYANEALFQAGISPLAAAGSLNTMQCERLVDAVKATLLRAIKAGGSSLRDFTDCEGSPGYFQQQYWVYGRAGQSCRQCGELVSKTRQGQRSTFFCARCQH
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
Q82S12
Q9KU20
RLUD_VIBCH
rRNA-uridine isomerase D
Vibrio
MAHQIELTQTVKDSQLGQRLDQAVAELFTDFSRSRLKEWLLEGKIAVNGDVITKPRTKVMGGEVITVQAELEDEQRWEAQDLPLNIVYEDDDIIVINKPRDFVVHPGAGQADKTVLNALLFHYSPIAEVPRAGIVHRLDKDTTGLMVVAKTVPAQTRLVRALQKRDVTREYEAIVIGTMTAGGMIDKPIGRHSTKRTLMSVSPMGKHAVTHYRVAEHFREHTRLRLRLETGRTHQIRVHMAYLQHPLLGDTAYGGRARIPKGATEELTEMIRDFDRQALHAVMLKFEHPVTGEELEFHAPVPDDMVEMTLALREDAKLNRTEEY
Responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA.
Q9KU20
C5CUX0
RF2_VARPS
Peptide chain release factor 2
Variovorax
MDAEQINQIGATLADLSARTADLRRYLDYDAKAERLRTVNASLEDPNVWNDPKKAQELGREKKSLDDVVVTLDRLTSGLSDNTELYEMSKEDGDMDGLQSIADDAAALETDIKQLEFRRMFNNPADPLNAFVDIQAGAGGTEACDWASMLLRQYLKYAERKGFKTQIEDETPGDTAGIKGATIKVEGDYAFGLLRTETGVHRLVRKSPFDSSGGRHTSFASIFVYPEIDDSIEIEINPADVRTDTFRASGAGGQHINKTDSAVRLTHIPTGIVVQCQDGRSQHSNRDVAWKRLRSRLYDHEMRKRQEEQQKLEDSKTDVGWGHQIRSYVLDNSRIKDLRTNVEVSATQKVLDGDLDVFIEASLKQGV
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
C5CUX0
Q92A57
SCPA_LISIN
Segregation and condensation protein A
Listeria
MVEMNFKVEAFEGPLDLLLHLIGQLEVDIYDIPMAEITDQYMEFVHTMQEMELDVASEYLVMAATLLAIKSKMLLPKQELEIDYDTLEEEEDPRDALVEKLMEYKRFKEAAKELKEKEAERSFYFSKPPMDLAEYDEGTKVAELDVSLNDMLSAFNKMLRRKKLNKPLHTRITTQEISIDDRMNSVLGKLHQQTNHRLRFDELFEEQTKEQLVVTFLALLELMKRKLVEVEQSASFADLYVQGKGEELS
Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
Q92A57