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<|newrecord|> nctId: NCT06352112 id: 02.04.2024 - POP briefTitle: Effects of the Hypopressive Exercises in Women With Pelvic Organ Prolapse overallStatus: COMPLETED date: 2023-03-15 date: 2024-01-15 date: 2024-02-15 date: 2024-04-08 date: 2024-04-10 name: Hacettepe University class: OTHER name: Istanbul Training and Re... |
<|newrecord|> nctId: NCT06352099 id: 6315 briefTitle: Dietary Supplementation and Cognitive Functions in the Elderly acronym: ESPINS overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2024-11 date: 2025-04 date: 2024-04-08 date: 2024-04-08 name: Fondazione Policlinico Universitario Agostino Gemelli IRCCS class: OTHE... |
Age-related evolution is a gradual and continuous process involving a series of physical and cognitive changes, which, however, has no real 'onset' age. In fact, rather than chronological age, the concept of 'elderly' is based on the individual's degree of self-sufficiency and independence. From a biological point of v... |
An important factor in counteracting frailty is nutritional intake. Humans ingest approximately 500 g of chemical compounds daily through their diet, most of which are components of plants or vegetables in general. In addition to the well-known macronutrients (proteins, fats, and carbohydrates) and micronutrients (mine... |
Phytochemical compounds are an extremely diverse set of elements that, when taken at significant levels, have a protective effect on human health. These substances exert various biological functions, such as antioxidant activity, modulation of detoxifying enzymes, stimulation of the immune system, reduction of platelet... |
Among the phytochemical compounds, flavonoids represent a category of polyfunctional substances with high bioactivity, comprising more than 5000 compounds. They possess biochemical properties of functional interest in the nutritional and therapeutic fields; for example, rutin, diosmin, and hesperidin are present in som... |
However, few studies have evaluated the effect of hesperidin and proanthocyanidins on motor, cognitive, and functional aspects in the elderly. |
Altemor® is a food supplement based on micronized diosmin, hesperidin, and herbal extracts that has an important integrative supporting action in optimising blood microcirculation. |
The aim of the study is to evaluate the contribution of dietary supplementation with Altemor® on cognitive function, balance, fatigue, and some domains of quality of life in elderly subjects. conditions: Cognitive Impairment conditions: Old Age; Debility studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED inter... |
<|newrecord|> nctId: NCT06352086 id: STUDY00009227 briefTitle: Understanding Visual Processing After Occipital Stroke overallStatus: NOT_YET_RECRUITING date: 2024-09 date: 2028-09 date: 2029-09 date: 2024-04-08 date: 2024-04-08 name: University of Rochester class: OTHER briefSummary: The purpose of this study is to inv... |
<|newrecord|> nctId: NCT06352073 id: 23-2625 id: R668-EE-2380 type: OTHER domain: Regeneron briefTitle: Dupilumab for Eosinophilic Esophagitis With Severe Strictures acronym: DESTRICT overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2025-11 date: 2026-04 date: 2024-04-08 date: 2024-04-08 name: University of North ... |
Participants will have a screening visit where they will complete surveys and undergo an endoscopy (EGD). Blood and biopsies (small tissue samples) will also be collected. If eligible and enrolled into the study, participants will receive weekly subcutaneous (under the skin) injections of dupilumab for 52 weeks (one ye... |
Participants will return for study visits every at weeks 4, 8, 12, 18, 24, 30, 36, 44, and 52. During these visits, vital signs (temperature, heart rate, etc.) will be collected and participants will complete surveys. During visits at week 12, 24, and 52, blood will be collected and an endoscopy with biopsy will be per... |
At 64 weeks (12 weeks after the last dose of dupilumab), participants assigned male at birth (AMAB) will be contacted about their / their partner's pregnancy status and participants assigned female at birth (AFAB) may be asked to come for an in-person visit to complete a urine pregnancy test. conditions: Eosinophilic E... |
<|newrecord|> nctId: NCT06352060 id: KCHRRF_MONITOR AF_030 briefTitle: Dynamic Data-Driven Management of Atrial Fibrillation Using Implantable Cardiac Monitors: The MONITOR-AF Study overallStatus: RECRUITING date: 2024-04 date: 2024-06 date: 2024-09 date: 2024-04-08 date: 2024-04-08 name: Kansas City Heart Rhythm Resea... |
<|newrecord|> nctId: NCT06352047 id: Karadeniz Tech. University briefTitle: The Effects of Positioning After Extubation of Preterm Infants on the Respiratory Functions overallStatus: COMPLETED date: 2018-11-01 date: 2019-06-01 date: 2019-06-01 date: 2024-04-08 date: 2024-04-08 name: Karadeniz Technical University class... |
Hypothesis 0a (H0a): There is no difference between the oxygen saturation (SpO2) levels of preterm infants in supine and prone positions after extubation. |
Hypothesis 0b (H0b): There is no difference between the respiratory rate of preterm infants in supine and prone positions after extubation. |
Hypothesis 0c (H0c): There is no difference between the respiratory rhythms of preterm infants in supine and prone positions after extubation. |
Hypothesis 0d (H0d): There is no difference between respiratory distress in preterm infants in supine and prone positions after extubation. conditions: Premature Infants studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Simple randomization method was ... |
<|newrecord|> nctId: NCT06352034 id: Empathy Training for Students briefTitle: Empathy Training for Future Mental Health Practitioners in University Students overallStatus: NOT_YET_RECRUITING date: 2024-03-30 date: 2024-04-30 date: 2024-10-01 date: 2024-04-08 date: 2024-04-08 name: Peking University class: OTHER briefS... |
<|newrecord|> nctId: NCT06352021 id: KAHRİMAN İlknur briefTitle: The Effect of Distraction With a Kaleidoscope on the Level of Perceived Pain During Blood Sampling in Children overallStatus: COMPLETED date: 2019-05-30 date: 2019-06-30 date: 2019-06-30 date: 2024-04-08 date: 2024-04-08 name: İlknur KAHRİMAN class: OTHER... |
Hypothesis 0 (H0): There is no difference between the pain scores of the kaleidoscope group and the control group during blood sampling. |
Hypothesis 1 (H1): There is a difference between the pain scores of the kaleidoscope group and the control group during blood sampling. conditions: Pain studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: ... |
<|newrecord|> nctId: NCT06352008 id: Zhansheng Jiang briefTitle: To Evaluate the Efficacy and Safety of Anrotinib Hydrochloride Capsule in Postoperative Non-pCR Patients With Non-small Cell Lung Cancer overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2025-06-01 date: 2026-06-01 date: 2024-04-08 date: 2024-04-08... |
<|newrecord|> nctId: NCT06351995 id: KOR-19-22 briefTitle: Neostigmine and Glycopyrrolate by Iontophoresis overallStatus: ACTIVE_NOT_RECRUITING date: 2020-11-06 date: 2022-10-25 date: 2025-01-01 date: 2024-04-08 date: 2024-04-08 name: James J. Peters Veterans Affairs Medical Center class: FED briefSummary: To determine... |
<|newrecord|> nctId: NCT06351982 id: 211123PER3-3-2 briefTitle: Treatment Of Shallow Periodontal Pockets 4-6mm Using AIRFLOW Prophylaxis Master Device With Erythritol vs Manual Scalers overallStatus: RECRUITING date: 2024-03-01 date: 2025-06-01 date: 2026-01-01 date: 2024-04-08 date: 2024-04-08 name: Cairo University c... |
Both hand and ultrasonic instruments are characterized by being time-consuming and requiring technical skill, often causing patient discomfort and post-treatment pain, including hypersensitivity resulting from the loss of hard tissue when scaling the tooth surface. Ultrasonic instruments tend to leave a rougher surface... |
The aim of this study is to evaluate changes in probing depth clinically, Bleeding on probing, Clinical attachment level, Plaque index, Calculus index, Patient pain/discomfort, Patient satisfaction, Cost effectiveness, Treatment time and Number of pockets closed after using AIRFLOW® Prophylaxis Master device with eryth... |
<|newrecord|> nctId: NCT06351969 id: Ms 9-12-2023 briefTitle: Evaluating Placental Thickness and Thickness of Uterine Muscle at Placenta Attachment in Prediction of Postpartum Blood Loss overallStatus: RECRUITING date: 2023-12-21 date: 2024-12 date: 2024-12 date: 2024-04-08 date: 2024-04-08 name: Benha University class... |
<|newrecord|> nctId: NCT06351956 id: Arrhythmias in Septic Patients briefTitle: New Onset Cardiac Arrhythmias in Septic Patients in Critical Care Setting, Predictors and Outcomes. overallStatus: NOT_YET_RECRUITING date: 2024-04-20 date: 2026-04-20 date: 2026-12-30 date: 2024-04-08 date: 2024-04-08 name: Assiut Universi... |
<|newrecord|> nctId: NCT06351943 id: ImageDB pilot briefTitle: Proximal Femur Image Database Validation overallStatus: ACTIVE_NOT_RECRUITING date: 2021-05-01 date: 2024-10-01 date: 2025-06-30 date: 2024-04-08 date: 2024-04-08 name: AO Innovation Translation Center class: OTHER name: University of Turin, Italy briefSumm... |
The goal of this project is to determine the agreement between the Turin annotation of fracture status and the annotation from an external group of AO expert surgeons for a random subset of the Turin images. conditions: Proximal Femoral Fracture studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: CROSS_... |
<|newrecord|> nctId: NCT06351930 id: EA210473 briefTitle: CBT for Insomnia in Adolescents With ADHD overallStatus: RECRUITING date: 2023-01-01 date: 2025-12-31 date: 2025-12-31 date: 2024-04-08 date: 2024-04-08 name: The University of Hong Kong class: OTHER name: Kwai Chung Hospital, Hong Kong briefSummary: Insomnia an... |
<|newrecord|> nctId: NCT06351917 id: LEVEXE briefTitle: Effect of Topical PlexoZome® Levagen® Spray on Relief of Post Exercise Knee Joint Pain overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-04-01 date: 2025-05-01 date: 2024-04-08 date: 2024-04-10 name: RDC Clinical Pty Ltd class: INDUSTRY briefSummary: T... |
<|newrecord|> nctId: NCT06351904 id: RAG-01-01 briefTitle: A Study of RAG-01 in Patients With Non-muscle-invasive Bladder Cancer (NMIBC) Who Have Failed Bacillus Calmette Guérin (BCG) Therapy overallStatus: RECRUITING date: 2024-04-03 date: 2025-06-30 date: 2025-08-31 date: 2024-04-08 date: 2024-04-16 name: Ractigen Th... |
<|newrecord|> nctId: NCT06351891 id: SHARE2402 briefTitle: Efficacy and Safety of Bismuth Quadruple Therapy Containing Cefuroxime and Tetracycline as First-line Therapy for Eradicating Helicobacter Pylori in Patients Allergic to Penicillin overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2024-12 date: 2024-12 date... |
<|newrecord|> nctId: NCT06351878 id: Pro00113559 briefTitle: TipTraQ Home Sleep Test Validation Study overallStatus: RECRUITING date: 2024-02-28 date: 2024-08-23 date: 2024-08-23 date: 2024-04-08 date: 2024-04-08 name: PranaQ Pte. Ltd. class: INDUSTRY briefSummary: A validation study has been designed to assess the per... |
<|newrecord|> nctId: NCT06351865 id: PHU/2023/21 briefTitle: Feasibility Study to Evaluate the Use of Patient Reported Complications After Digital Consent acronym: PRC overallStatus: RECRUITING date: 2024-03-07 date: 2024-09-19 date: 2024-10-31 date: 2024-04-08 date: 2024-04-09 name: Portsmouth Hospitals NHS Trust clas... |
<|newrecord|> nctId: NCT06351852 id: 1678243 briefTitle: Transdermal Administration by a Novel Wireless Iontophoresis Device overallStatus: RECRUITING date: 2022-03-22 date: 2025-02-15 date: 2025-02-15 date: 2024-04-08 date: 2024-04-08 name: James J. Peters Veterans Affairs Medical Center class: FED briefSummary: Perso... |
The ability to move the bowel contents along to the rectum was severely impaired primary because of poor gut contractions on the left side of the colon, as shown by our team of investigators. To address this problem, a dual medication combination (neostigmine and glycopyrrolate) was developed that safely and predictabl... |
The proposed research project to determine the safety of positively charged compounds (e.g., vitamin B12, NEO, and GLY) administered transcutaneously by the prototype wireless ION device and to compare the pharmacokinetic profiles of transcutaneous administration of NEO and GLY by the wireless ION device to a commercia... |
<|newrecord|> nctId: NCT06351839 id: 2024/500457(REK) briefTitle: Sleep Well Despite Persistent Pain Symptoms acronym: Sleep-Well overallStatus: NOT_YET_RECRUITING date: 2024-10 date: 2026-12 date: 2027-12 date: 2024-04-08 date: 2024-04-08 name: University of Tromso class: OTHER name: University Hospital of North Norwa... |
Eligible patients: Investigators target adult patients referred to the University Hospital of North Norway (Tromsø) for a diagnostic evaluation of their pain condition. Patients eligible for the Sleep-Well study are those who satisfy diagnostic criteria for a non-malign pain disorder plus a comorbid insomnia sleep diso... |
Aims: This trial uses a randomized semi-crossover design to examine if the Sleep-Well group does better regarding insomnia and sleep quality than the control patients (TAU). The primary outcome measures are reductions in diagnostic criteria for insomnia, self-reported insomnia symptoms, quality of life, and actigraphy-... |
The intervention: The Sleep-Well program schedules group sessions that cover four topics (sleep literacy, behavioural and mental strategies, maintenance and relapse prevention). All sessions are led by two therapists. Those randomized to the active control group (TAU) cross over to the Sleep-Well intervention three mon... |
<|newrecord|> nctId: NCT06351826 id: 22070876 briefTitle: Effectiveness of ELLASI Intervention Towards Polytrauma Patients in the Emergency Department overallStatus: RECRUITING date: 2024-01-03 date: 2024-04 date: 2024-05 date: 2024-04-08 date: 2024-04-08 name: Indonesia University class: OTHER briefSummary: This clini... |
1. Is the response time of polytrauma patients who receive ELLASI in the intervention group faster than the control group? |
2. Is the deterioration score of polytrauma patients who receive ELLASI in the intervention group better than the control group? |
3. Is the metabolic status of polytrauma patients who receive ELLASI in the intervention group better than the control group? |
Polytrauma patients in the intervention group will receive ELLASI, a structured intervention consisting of the six following: |
1. Evaluation of airway and cervical control, remove the foreign body, fluid, etc., from the airway, |
2. Patient positioning and giving oxygen, head-up, |
3. Stabilisation, including IV insertion, applying pressure and bandage, place monitor, and haemodynamic monitoring |
4. Assessment: re-assessment of pain and other main complaints |
5. Make sure informed consents are documented |
6. Inform patient and family for further intervention |
Polytrauma patients in the control group will receive the usual/standard intervention. |
Response time, early warning score, and arterial blood gas of polytrauma patients from both groups will be obtained and documented before and after the intervention. conditions: Polytrauma studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE w... |
<|newrecord|> nctId: NCT06351813 id: B2024-029R briefTitle: Predicting Adverse Kidney Events of Cardiac Surgery-Associated Acute Kidney Injury Using Novel Biomarkers overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2026-12-31 date: 2027-12-31 date: 2024-04-08 date: 2024-04-08 name: Shanghai Zhongshan Hospital c... |
<|newrecord|> nctId: NCT06351800 id: PE-0280-2018 briefTitle: The PredictPlusPrevent Study overallStatus: NOT_YET_RECRUITING date: 2024-09-15 date: 2025-12-31 date: 2026-04-30 date: 2024-04-08 date: 2024-04-08 name: The Mediterranean Institute for the Advance of Biotechnology and Health Research class: OTHER briefSumma... |
Methods: A double-blind, parallel-group, randomized controlled trial with a twelve-month follow-up. The entire process of recruitment, random allocation, intervention, and follow-up will be conducted through the 'PredictPlusPrevent' platform and its associated apps. Following a media campaign, at least 9,000 Spanish pa... |
<|newrecord|> nctId: NCT06351787 id: 22-X-97 briefTitle: Project Soma: Cortical Activity of a Body Scan Meditation and Yoga Practice in Healthy Yogis overallStatus: COMPLETED date: 2022-10-31 date: 2023-06-28 date: 2023-06-28 date: 2024-04-08 date: 2024-04-08 name: Ohio University class: OTHER briefSummary: In this 2-a... |
Specifically, we will examine the correlates of interoceptive awareness and mindful awareness with cortical activity (Aim 1a) and pain tolerance (Aim 1b); determine cortical activity responsiveness of two brief awareness-focused meditations - a resting-based body scan practice and yoga practice (Aim 2a); characterize c... |
Our central hypotheses are that (Aim 1a) higher interoceptive awareness and mindful awareness will moderately correlate with higher cortical activity for both awareness-focused meditation practices; (Aim 1b) individuals sub-grouped into the 'acceptance in action cluster' based on 2 self-report measures will exhibit hig... |
<|newrecord|> nctId: NCT06351774 id: 21-F-45 briefTitle: Project AdaPT: An Adaptive Physiotherapy Intervention Augmented With a Healthy Mind Training Program for People With Chronic Low Back Pain acronym: AdaPT overallStatus: COMPLETED date: 2022-05-24 date: 2024-02-08 date: 2024-03-25 date: 2024-04-08 date: 2024-04-08... |
<|newrecord|> nctId: NCT06351761 id: SCT02-ECG briefTitle: WIBOFA - Validation of SCT02 With ECG-App for Detection of AF acronym: WIBOFA overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2025-01 date: 2025-03 date: 2024-04-08 date: 2024-04-08 name: Withings class: INDUSTRY briefSummary: The aim of the study is to e... |
<|newrecord|> nctId: NCT06351748 id: NN9535-7877 id: U1111-1296-3151 type: OTHER domain: World Health Organization (WHO) briefTitle: Real-world Study of CHina Ozempic cLinicAl pRactice in Patients With Type 2 Diabetes (SCHOLAR) acronym: SCHOLAR overallStatus: ENROLLING_BY_INVITATION date: 2024-04-05 date: 2024-06-30 da... |
<|newrecord|> nctId: NCT06351735 id: 2024-0336 briefTitle: Efficacy and Safety of Deep Cervical Lymph Node-vein Bypass Surgery in ALS Amyotrophic Lateral Sclerosis overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-05-01 date: 2027-05-01 date: 2024-04-08 date: 2024-04-08 name: Second Affiliated Hospital, Sch... |
<|newrecord|> nctId: NCT06351722 id: smokingnlrp3inflasome briefTitle: Non-surgical Periodontal Treatment in Smokers on SIRT-1, NLRP3 Inflammasome and LncRNAs overallStatus: NOT_YET_RECRUITING date: 2024-05-15 date: 2024-12-15 date: 2025-03-15 date: 2024-04-08 date: 2024-04-08 name: Necmettin Erbakan University class: ... |
The main questions it aims to answer are: |
question 1: Is there a relationship between the biomarkers mentioned above and periodontitis and smoking? question 2:How do the above-mentioned biomarkers change after NSPT in smokers and non-smokers? conditions: Periodontitis, Adult studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: PROSPECTIVE... |
<|newrecord|> nctId: NCT06351709 id: UmutPaksoy briefTitle: Acute Effects of Heat, Cold and Stretching on Knee Proprioception and Vertical Jump overallStatus: COMPLETED date: 2020-11-02 date: 2021-02-20 date: 2021-02-20 date: 2024-04-08 date: 2024-04-08 name: Istanbul Bilgi University class: OTHER briefSummary: The aim... |
<|newrecord|> nctId: NCT06351696 id: 43008563 briefTitle: The Effects of Bromelain Supplement in Patients With Ulcerative Colitis overallStatus: RECRUITING date: 2024-04-20 date: 2024-07-20 date: 2024-08-10 date: 2024-04-08 date: 2024-04-09 name: National Nutrition and Food Technology Institute class: OTHER briefSummar... |
IBDQ, SCCAIQ, CRP, TAC, TNF-a will be measured before and after the intervention. conditions: Ulcerative Colitis conditions: Primary Sclerosing Cholangitis studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: QUADRUPLE whoMasked: PARTICIPANT whoMaske... |
<|newrecord|> nctId: NCT06351683 id: 24-066-2 id: P30AG067988 type: NIH link: https://reporter.nih.gov/quickSearch/P30AG067988 briefTitle: Testing MitoQ on Lower Urinary Tract Symptoms in Older Women With Metabolic Syndrome acronym: Mito-LUTS overallStatus: RECRUITING date: 2024-04-03 date: 2025-12 date: 2025-12 date: ... |
* Is the study design feasible and acceptable to participants? |
* Do participants taking the study drug get any improvement to their bladder symptoms compared to participants taking a placebo (a look-alike substance that contains no drug)? |
Participants will take 2 capsules of the study drug every morning for 4 months, answer many questions about their health including questions about their bladder health, perform physical and cognitive testing, give blood and urine samples, collect urine over 24 hour periods 3 times over the 4 months of the study, comple... |
<|newrecord|> nctId: NCT06351670 id: 1109/2024 briefTitle: Personalised Monitoring of Early and Intermediate Age-related Macular Degeneration With Artificial Intelligence and Identification of Disease Progression acronym: SUDETES overallStatus: NOT_YET_RECRUITING date: 2024-07 date: 2027-07 date: 2027-07 date: 2024-04-... |
* Identify and quantify focal and global alterations in the retina in regard to disease progression. |
* Assess the individual risk of disease progression in intermediate AMD patients converting to advanced AMD based on imaging. |
* Specify the course of disease in regard to the sequence of events that lead to the conversion to advanced AMD |
* Enhance the ability to classify AMD using artificial intelligence in addition to traditional models. |
All patients will be followed for 24 months with 6 month intervals to assess clinical changes. Monitoring of disease progression will be performed using the following routine in-vivo imaging procedures: |
* Scanning Laser Fundus Photography |
* Color Fundus Photography (CFP) |
* Optical Coherence Tomography (OCT) |
* Optical Coherence Tomography Angiography (OCTA) Patients will be asked for their medical history. Standard ophthalmic examination, as well as a questionnaire on visual function will be carried out. |
No intervention will be performed during the study since no treatment is yet available within Europe. As soon as treatment is approved in the EU, patients in this cohort might receive treatment according to availability in their respective country and standard of care. If treatment will be performed, it will be as stan... |
<|newrecord|> nctId: NCT06351657 id: 1088/2024 briefTitle: Personalized Monitoring of Non-foveal, Non-vision Compromising Atrophic Age-related Macular Degeneration With Artificial Intelligence and Identification of Disease Progression acronym: APENNINES overallStatus: NOT_YET_RECRUITING date: 2024-07 date: 2027-07 date... |
* Assess the individual progression rate of a patient in non-foveal, non-vision compromising atrophic AMD and assess personalized risk of progression based on imaging. |
* Identify and quantify focal and global alterations in the retina in regard to disease progression. |
* Evaluate the monitoring of AMD progression using approved AI algorithms. |
All patients will be followed for 24 months with 6 month intervals to assess clinical changes. Monitoring of disease progression will be performed using the following routine in-vivo imaging procedures: |
* Scanning Laser Fundus Photography |
* Color Fundus Photography (CFP) |
* Optical Coherence Tomography (OCT) |
* Optical Coherence Tomography Angiography (OCTA) |
Patients will be asked for their medical history. Standard ophthalmic examination, as well as a questionnaire on visual function will be carried out. |
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